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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 16789

FusionGeneSummary for HS6ST2_NPFFR2

check button Fusion gene summary
Fusion gene informationFusion gene name: HS6ST2_NPFFR2
Fusion gene ID: 16789
HgeneTgene
Gene symbol

HS6ST2

NPFFR2

Gene ID

90161

10886

Gene nameheparan sulfate 6-O-sulfotransferase 2neuropeptide FF receptor 2
Synonyms-GPR74|HLWAR77|NPFF2|NPGPR
Cytomap

Xq26.2

4q13.3

Type of geneprotein-codingprotein-coding
Descriptionheparan-sulfate 6-O-sulfotransferase 2HS6ST-2neuropeptide FF receptor 2G-protein coupled receptor 74G-protein coupled receptor HLWAR77neuropeptide FF 2neuropeptide G-protein coupled receptor
Modification date2018052320180523
UniProtAcc

Q96MM7

Q9Y5X5

Ensembl transtripts involved in fusion geneENST00000370836, ENST00000521489, 
ENST00000370833, ENST00000406696, 
ENST00000602570, 		ENST00000308744, 
ENST00000344413, ENST00000395999, 
ENST00000358749, ENST00000506359, 
Fusion gene scores* DoF score2 X 2 X 2=82 X 1 X 2=4
# samples 22
** MAII scorelog2(2/8*10)=1.32192809488736log2(2/4*10)=2.32192809488736
Context

PubMed: HS6ST2 [Title/Abstract] AND NPFFR2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVBLCATCGA-BT-A2LD-01AHS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000370836ENST00000308744HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
Frame-shiftENST00000370836ENST00000344413HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
In-frameENST00000370836ENST00000395999HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
In-frameENST00000370836ENST00000358749HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
5CDS-intronENST00000370836ENST00000506359HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
In-frameENST00000521489ENST00000308744HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
Frame-shiftENST00000521489ENST00000344413HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
In-frameENST00000521489ENST00000395999HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
In-frameENST00000521489ENST00000358749HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
5CDS-intronENST00000521489ENST00000506359HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
Frame-shiftENST00000370833ENST00000308744HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
In-frameENST00000370833ENST00000344413HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
Frame-shiftENST00000370833ENST00000395999HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
Frame-shiftENST00000370833ENST00000358749HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
5CDS-intronENST00000370833ENST00000506359HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
intron-3CDSENST00000406696ENST00000308744HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
intron-3CDSENST00000406696ENST00000344413HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
intron-3CDSENST00000406696ENST00000395999HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
intron-3CDSENST00000406696ENST00000358749HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
intron-intronENST00000406696ENST00000506359HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
intron-3CDSENST00000602570ENST00000308744HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
intron-3CDSENST00000602570ENST00000344413HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
intron-3CDSENST00000602570ENST00000395999HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
intron-3CDSENST00000602570ENST00000358749HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+
intron-intronENST00000602570ENST00000506359HS6ST2chrX

132090836

-NPFFR2chr4

73003757

+

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FusionProtFeatures for HS6ST2_NPFFR2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
HS6ST2

Q96MM7

NPFFR2

Q9Y5X5

Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide)neuropeptides, also known as morphine-modulating peptides. Canalso be activated by a variety of naturally occurring or syntheticFMRF-amide like ligands. This receptor mediates its action byassociation with G proteins that activate a phosphatidylinositol-calcium second messenger system.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000370836-34233_241315606RegionPAPS binding
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000370836-34263_264315606RegionSubstrate binding
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000521489-36233_241315646RegionPAPS binding
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000521489-36263_264315646RegionSubstrate binding
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000370836-341_4315606Topological domainCytoplasmic
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000521489-361_4315646Topological domainCytoplasmic
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000370836-345_27315606TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000521489-365_27315646TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14243_262211523Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14284_319211523Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14341_377211523Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14399_413211523Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14435_522211523Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03169_18499311Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03206_22199311Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03243_26299311Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03284_31999311Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03341_37799311Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03399_41399311Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03435_52299311Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14169_184109421Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14206_221109421Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14243_262109421Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14284_319109421Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14341_377109421Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14399_413109421Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14435_522109421Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25169_184112424Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25206_221112424Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25243_262112424Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25284_319112424Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25341_377112424Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25399_413112424Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25435_522112424Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14222_242211523TransmembraneHelical%3B Name%3D3
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14263_283211523TransmembraneHelical%3B Name%3D4
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14320_340211523TransmembraneHelical%3B Name%3D5
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14378_398211523TransmembraneHelical%3B Name%3D6
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14414_434211523TransmembraneHelical%3B Name%3D7
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03148_16899311TransmembraneHelical%3B Name%3D1
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03185_20599311TransmembraneHelical%3B Name%3D2
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03222_24299311TransmembraneHelical%3B Name%3D3
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03263_28399311TransmembraneHelical%3B Name%3D4
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03320_34099311TransmembraneHelical%3B Name%3D5
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03378_39899311TransmembraneHelical%3B Name%3D6
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+03414_43499311TransmembraneHelical%3B Name%3D7
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14148_168109421TransmembraneHelical%3B Name%3D1
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14185_205109421TransmembraneHelical%3B Name%3D2
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14222_242109421TransmembraneHelical%3B Name%3D3
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14263_283109421TransmembraneHelical%3B Name%3D4
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14320_340109421TransmembraneHelical%3B Name%3D5
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14378_398109421TransmembraneHelical%3B Name%3D6
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+14414_434109421TransmembraneHelical%3B Name%3D7
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25148_168112424TransmembraneHelical%3B Name%3D1
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25185_205112424TransmembraneHelical%3B Name%3D2
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25222_242112424TransmembraneHelical%3B Name%3D3
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25263_283112424TransmembraneHelical%3B Name%3D4
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25320_340112424TransmembraneHelical%3B Name%3D5
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25378_398112424TransmembraneHelical%3B Name%3D6
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+25414_434112424TransmembraneHelical%3B Name%3D7

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000370836-34457_459315606RegionPAPS binding
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000370836-34463_464315606RegionPAPS binding
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000521489-36457_459315646RegionPAPS binding
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000521489-36463_464315646RegionPAPS binding
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000370836-3428_605315606Topological domainLumenal
HgeneHS6ST2chrX:132090836chr4:73003757ENST00000521489-3628_605315646Topological domainLumenal
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14169_184211523Topological domainCytoplasmic
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+141_147211523Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14206_221211523Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000344413+031_14799311Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000358749+141_147109421Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000395999+251_147112424Topological domainExtracellular
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14148_168211523TransmembraneHelical%3B Name%3D1
TgeneNPFFR2chrX:132090836chr4:73003757ENST00000308744+14185_205211523TransmembraneHelical%3B Name%3D2


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FusionGeneSequence for HS6ST2_NPFFR2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_HS6ST2_ENST00000370836_chrX_132090836_-_NPFFR2_ENST00000308744_chr4_73003757_+_311aa
DGHLETRCARSVDWSREYLSQLQSLRXLQLLXIGSSVWSTLLNQSSLSRQRLSLLXSSGSXPSPLCLHLQXCYMCKKKNITEXDSTPRIK
PVQSTGAGKTGQIRKXGRSTPLCCLPTSTWLPSPSLSSCMEGLEFHSSGLQFLTQAGRTRSSGTWCPGRSRRSLRCSXLWPCFLFSHGCP
CGLXXCSQTTLTFLQMNCRSSTSTSTLLHTGWHSATAVSIPSFMVSSTRISAVVSKKLSSSSSAKKEQSLWKLMPXKLKAMCSXTHLISL

>In-frame_HS6ST2_ENST00000370836_chrX_132090836_-_NPFFR2_ENST00000395999_chr4_73003757_+_311aa
DGHLETRCARSVDWSREYLSQLQSLRXLQLLXIGSSVWSTLLNQSSLSRQRLSLLXSSGSXPSPLCLHLQXCYMCKKKNITEXDSTPRIK
PVQSTGAGKTGQIRKXGRSTPLCCLPTSTWLPSPSLSSCMEGLEFHSSGLQFLTQAGRTRSSGTWCPGRSRRSLRCSXLWPCFLFSHGCP
CGLXXCSQTTLTFLQMNCRSSTSTSTLLHTGWHSATAVSIPSFMVSSTRISAVVSKKLSSSSSAKKEQSLWKLMPXKLKAMCSXTHLISL

>In-frame_HS6ST2_ENST00000370836_chrX_132090836_-_NPFFR2_ENST00000358749_chr4_73003757_+_311aa
DGHLETRCARSVDWSREYLSQLQSLRXLQLLXIGSSVWSTLLNQSSLSRQRLSLLXSSGSXPSPLCLHLQXCYMCKKKNITEXDSTPRIK
PVQSTGAGKTGQIRKXGRSTPLCCLPTSTWLPSPSLSSCMEGLEFHSSGLQFLTQAGRTRSSGTWCPGRSRRSLRCSXLWPCFLFSHGCP
CGLXXCSQTTLTFLQMNCRSSTSTSTLLHTGWHSATAVSIPSFMVSSTRISAVVSKKLSSSSSAKKEQSLWKLMPXKLKAMCSXTHLISL

>In-frame_HS6ST2_ENST00000521489_chrX_132090836_-_NPFFR2_ENST00000308744_chr4_73003757_+_627aa
MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSHGFHTRPLLDKPRKASSSLAGAACAPLFALL
SRGRRRRMHVLRRRWDLGSLCRALLTRGLAALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQL
LRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRP
GKRETWLFSRFSTGWSCGLHADWTELTSCVPSVVDGKRDARLRPSRMAIWKHDVQDQWIGPGNICRSFSLYVSCNCCRXVPVCGLPFXTK
AHYQDSVCHYYDHLGPSHHHYVSICSNVTCARRKILPSETQLPEXNQSSLLVPGRLAKSGNEEDLHHCAVCQHLPGSPLPHCHHVWKDWN
FTLQGCSSSHRQEEPGAVARGVQEEAEDHXDAPDCGPAFYSLMAAPVDSNDALRLRXPFSKXTADHQHLHLPFCTLAGIRQQQCQSHHLW

>In-frame_HS6ST2_ENST00000521489_chrX_132090836_-_NPFFR2_ENST00000395999_chr4_73003757_+_627aa
MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSHGFHTRPLLDKPRKASSSLAGAACAPLFALL
SRGRRRRMHVLRRRWDLGSLCRALLTRGLAALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQL
LRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRP
GKRETWLFSRFSTGWSCGLHADWTELTSCVPSVVDGKRDARLRPSRMAIWKHDVQDQWIGPGNICRSFSLYVSCNCCRXVPVCGLPFXTK
AHYQDSVCHYYDHLGPSHHHYVSICSNVTCARRKILPSETQLPEXNQSSLLVPGRLAKSGNEEDLHHCAVCQHLPGSPLPHCHHVWKDWN
FTLQGCSSSHRQEEPGAVARGVQEEAEDHXDAPDCGPAFYSLMAAPVDSNDALRLRXPFSKXTADHQHLHLPFCTLAGIRQQQCQSHHLW

>In-frame_HS6ST2_ENST00000521489_chrX_132090836_-_NPFFR2_ENST00000358749_chr4_73003757_+_627aa
MALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSHGFHTRPLLDKPRKASSSLAGAACAPLFALL
SRGRRRRMHVLRRRWDLGSLCRALLTRGLAALGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQL
LRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRP
GKRETWLFSRFSTGWSCGLHADWTELTSCVPSVVDGKRDARLRPSRMAIWKHDVQDQWIGPGNICRSFSLYVSCNCCRXVPVCGLPFXTK
AHYQDSVCHYYDHLGPSHHHYVSICSNVTCARRKILPSETQLPEXNQSSLLVPGRLAKSGNEEDLHHCAVCQHLPGSPLPHCHHVWKDWN
FTLQGCSSSHRQEEPGAVARGVQEEAEDHXDAPDCGPAFYSLMAAPVDSNDALRLRXPFSKXTADHQHLHLPFCTLAGIRQQQCQSHHLW

>In-frame_HS6ST2_ENST00000370833_chrX_132090836_-_NPFFR2_ENST00000344413_chr4_73003757_+_203aa
MDEKSNKLLLALVMLFLFAVIVLQYVCPGTECQLLRLQAFSSPVPDPYRSEDESSARFVPRYNFTRGDLLRKVDFDIKGDDLIVFLHIQK
TGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGWSCGLHADWTELTSCVPSVVDGKRDARLRPSRMAIWKHDVQD


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_HS6ST2_ENST00000370836_chrX_132090836_-_NPFFR2_ENST00000308744_chr4_73003757_+_935nt
GATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGTCCAGGGAATATCTGTCGCAGCTTCAGTCTTTACGTTAGTTGCAATTG
CTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAAGCTCACTATCAAGACAGCGTTTGTCATTATTATGATCATCTGGGTCC
TAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGTGCAAGAAGAAAAATATTACCGAGTGAGACTCAACTCCCAGAATAAAA
CCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGAAATGAGGAAGATCTACACCACTGTGCTGTTTGCCAACATCTACCTGG
CTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAATTTCACTCTTCAGGGCTGCAGTTCCTCACACAGGCAGGAAGAACCAGG
AGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAAGATGCTCCTGATTGTGGCCCTGCTTTTTATTCTCTCATGGCTGCCCC
TGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCCAAATGAACTGCAGATCATCAACATCTACATCTACCCTTTTGCACACT
GGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGGTTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAAGAAGCTTTCCAGC
TCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGCCCTAAAAGCTAAAAGCCATGTGCTCATAAACACATCTAATCAGCTTG
TCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCTTTATAGGAAAAGTGCTGAAAAACCCCAACAGGAATTAGTGATGGAAG

>In-frame_HS6ST2_ENST00000370836_chrX_132090836_-_NPFFR2_ENST00000395999_chr4_73003757_+_935nt
GATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGTCCAGGGAATATCTGTCGCAGCTTCAGTCTTTACGTTAGTTGCAATTG
CTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAAGCTCACTATCAAGACAGCGTTTGTCATTATTATGATCATCTGGGTCC
TAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGTGCAAGAAGAAAAATATTACCGAGTGAGACTCAACTCCCAGAATAAAA
CCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGAAATGAGGAAGATCTACACCACTGTGCTGTTTGCCAACATCTACCTGG
CTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAATTTCACTCTTCAGGGCTGCAGTTCCTCACACAGGCAGGAAGAACCAGG
AGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAAGATGCTCCTGATTGTGGCCCTGCTTTTTATTCTCTCATGGCTGCCCC
TGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCCAAATGAACTGCAGATCATCAACATCTACATCTACCCTTTTGCACACT
GGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGGTTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAAGAAGCTTTCCAGC
TCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGCCCTAAAAGCTAAAAGCCATGTGCTCATAAACACATCTAATCAGCTTG
TCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCTTTATAGGAAAAGTGCTGAAAAACCCCAACAGGAATTAGTGATGGAAG

>In-frame_HS6ST2_ENST00000370836_chrX_132090836_-_NPFFR2_ENST00000358749_chr4_73003757_+_935nt
GATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGTCCAGGGAATATCTGTCGCAGCTTCAGTCTTTACGTTAGTTGCAATTG
CTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAAGCTCACTATCAAGACAGCGTTTGTCATTATTATGATCATCTGGGTCC
TAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGTGCAAGAAGAAAAATATTACCGAGTGAGACTCAACTCCCAGAATAAAA
CCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGAAATGAGGAAGATCTACACCACTGTGCTGTTTGCCAACATCTACCTGG
CTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAATTTCACTCTTCAGGGCTGCAGTTCCTCACACAGGCAGGAAGAACCAGG
AGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAAGATGCTCCTGATTGTGGCCCTGCTTTTTATTCTCTCATGGCTGCCCC
TGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCCAAATGAACTGCAGATCATCAACATCTACATCTACCCTTTTGCACACT
GGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGGTTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAAGAAGCTTTCCAGC
TCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGCCCTAAAAGCTAAAAGCCATGTGCTCATAAACACATCTAATCAGCTTG
TCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCTTTATAGGAAAAGTGCTGAAAAACCCCAACAGGAATTAGTGATGGAAG

>In-frame_HS6ST2_ENST00000521489_chrX_132090836_-_NPFFR2_ENST00000308744_chr4_73003757_+_1882nt
ATGGCACTGCCTGCGTGTGCAGTCCGGGAGTTCGAGCCGCCGCGGCAACCGGAGCGAGGAGCGCCCGTCCGCACCACCTGTCCCCGCCGG
CATTCCAGAGTAGAGGCCGAATTGGCAGCGAGCCGGCCCGGGTCGGTCGCCGCCTCAGTTCGCGCGGGCCCTCCTAGGGGTGTGTCTCAC
GGATTCCACACCCGGCCGCTCCTGGACAAGCCCCGAAAGGCGTCTTCTTCCCTGGCGGGAGCCGCGTGCGCCCCGCTTTTCGCGCTGCTG
TCCCGGGGCCGCCGCAGGCGGATGCACGTCCTCAGGCGACGCTGGGACCTGGGCTCCCTCTGCCGGGCCCTGCTCACTCGGGGCCTGGCC
GCCCTGGGCCACTCGCTGAAGCACGTGCTCGGTGCGATCTTCTCCAAGATTTTCGGCCCCATGGCCAGCGTCGGGAACATGGATGAGAAA
TCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCTTCCTATTTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACAGAATGCCAGCTC
CTCCGCCTGCAGGCGTTCAGCTCCCCGGTGCCGGACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCCCGCTACAATTTC
ACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCGACATCAAGGGCGATGACCTGATCGTGTTCCTGCACATCCAGAAGACCGGGGGCACC
ACTTTCGGCCGCCACTTGGTGCGTAACATCCAGCTGGAGCAGCCGTGCGAGTGCCGCGTGGGTCAGAAGAAATGCACTTGCCACCGGCCG
GGTAAGCGGGAAACCTGGCTCTTCTCCAGGTTCTCCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTCACCAGCTGTGTG
CCCTCCGTGGTGGACGGCAAGCGCGACGCCAGGCTGAGACCGTCCAGGATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGT
CCAGGGAATATCTGTCGCAGCTTCAGTCTTTACGTTAGTTGCAATTGCTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAA
GCTCACTATCAAGACAGCGTTTGTCATTATTATGATCATCTGGGTCCTAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGT
GCAAGAAGAAAAATATTACCGAGTGAGACTCAACTCCCAGAATAAAACCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGA
AATGAGGAAGATCTACACCACTGTGCTGTTTGCCAACATCTACCTGGCTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAAT
TTCACTCTTCAGGGCTGCAGTTCCTCACACAGGCAGGAAGAACCAGGAGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAA
GATGCTCCTGATTGTGGCCCTGCTTTTTATTCTCTCATGGCTGCCCCTGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCC
AAATGAACTGCAGATCATCAACATCTACATCTACCCTTTTGCACACTGGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGG
TTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAAGAAGCTTTCCAGCTCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGC
CCTAAAAGCTAAAAGCCATGTGCTCATAAACACATCTAATCAGCTTGTCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCT

>In-frame_HS6ST2_ENST00000521489_chrX_132090836_-_NPFFR2_ENST00000395999_chr4_73003757_+_1882nt
ATGGCACTGCCTGCGTGTGCAGTCCGGGAGTTCGAGCCGCCGCGGCAACCGGAGCGAGGAGCGCCCGTCCGCACCACCTGTCCCCGCCGG
CATTCCAGAGTAGAGGCCGAATTGGCAGCGAGCCGGCCCGGGTCGGTCGCCGCCTCAGTTCGCGCGGGCCCTCCTAGGGGTGTGTCTCAC
GGATTCCACACCCGGCCGCTCCTGGACAAGCCCCGAAAGGCGTCTTCTTCCCTGGCGGGAGCCGCGTGCGCCCCGCTTTTCGCGCTGCTG
TCCCGGGGCCGCCGCAGGCGGATGCACGTCCTCAGGCGACGCTGGGACCTGGGCTCCCTCTGCCGGGCCCTGCTCACTCGGGGCCTGGCC
GCCCTGGGCCACTCGCTGAAGCACGTGCTCGGTGCGATCTTCTCCAAGATTTTCGGCCCCATGGCCAGCGTCGGGAACATGGATGAGAAA
TCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCTTCCTATTTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACAGAATGCCAGCTC
CTCCGCCTGCAGGCGTTCAGCTCCCCGGTGCCGGACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCCCGCTACAATTTC
ACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCGACATCAAGGGCGATGACCTGATCGTGTTCCTGCACATCCAGAAGACCGGGGGCACC
ACTTTCGGCCGCCACTTGGTGCGTAACATCCAGCTGGAGCAGCCGTGCGAGTGCCGCGTGGGTCAGAAGAAATGCACTTGCCACCGGCCG
GGTAAGCGGGAAACCTGGCTCTTCTCCAGGTTCTCCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTCACCAGCTGTGTG
CCCTCCGTGGTGGACGGCAAGCGCGACGCCAGGCTGAGACCGTCCAGGATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGT
CCAGGGAATATCTGTCGCAGCTTCAGTCTTTACGTTAGTTGCAATTGCTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAA
GCTCACTATCAAGACAGCGTTTGTCATTATTATGATCATCTGGGTCCTAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGT
GCAAGAAGAAAAATATTACCGAGTGAGACTCAACTCCCAGAATAAAACCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGA
AATGAGGAAGATCTACACCACTGTGCTGTTTGCCAACATCTACCTGGCTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAAT
TTCACTCTTCAGGGCTGCAGTTCCTCACACAGGCAGGAAGAACCAGGAGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAA
GATGCTCCTGATTGTGGCCCTGCTTTTTATTCTCTCATGGCTGCCCCTGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCC
AAATGAACTGCAGATCATCAACATCTACATCTACCCTTTTGCACACTGGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGG
TTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAAGAAGCTTTCCAGCTCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGC
CCTAAAAGCTAAAAGCCATGTGCTCATAAACACATCTAATCAGCTTGTCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCT

>In-frame_HS6ST2_ENST00000521489_chrX_132090836_-_NPFFR2_ENST00000358749_chr4_73003757_+_1882nt
ATGGCACTGCCTGCGTGTGCAGTCCGGGAGTTCGAGCCGCCGCGGCAACCGGAGCGAGGAGCGCCCGTCCGCACCACCTGTCCCCGCCGG
CATTCCAGAGTAGAGGCCGAATTGGCAGCGAGCCGGCCCGGGTCGGTCGCCGCCTCAGTTCGCGCGGGCCCTCCTAGGGGTGTGTCTCAC
GGATTCCACACCCGGCCGCTCCTGGACAAGCCCCGAAAGGCGTCTTCTTCCCTGGCGGGAGCCGCGTGCGCCCCGCTTTTCGCGCTGCTG
TCCCGGGGCCGCCGCAGGCGGATGCACGTCCTCAGGCGACGCTGGGACCTGGGCTCCCTCTGCCGGGCCCTGCTCACTCGGGGCCTGGCC
GCCCTGGGCCACTCGCTGAAGCACGTGCTCGGTGCGATCTTCTCCAAGATTTTCGGCCCCATGGCCAGCGTCGGGAACATGGATGAGAAA
TCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCTTCCTATTTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACAGAATGCCAGCTC
CTCCGCCTGCAGGCGTTCAGCTCCCCGGTGCCGGACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCCCGCTACAATTTC
ACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCGACATCAAGGGCGATGACCTGATCGTGTTCCTGCACATCCAGAAGACCGGGGGCACC
ACTTTCGGCCGCCACTTGGTGCGTAACATCCAGCTGGAGCAGCCGTGCGAGTGCCGCGTGGGTCAGAAGAAATGCACTTGCCACCGGCCG
GGTAAGCGGGAAACCTGGCTCTTCTCCAGGTTCTCCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTCACCAGCTGTGTG
CCCTCCGTGGTGGACGGCAAGCGCGACGCCAGGCTGAGACCGTCCAGGATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGT
CCAGGGAATATCTGTCGCAGCTTCAGTCTTTACGTTAGTTGCAATTGCTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAA
GCTCACTATCAAGACAGCGTTTGTCATTATTATGATCATCTGGGTCCTAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGT
GCAAGAAGAAAAATATTACCGAGTGAGACTCAACTCCCAGAATAAAACCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGA
AATGAGGAAGATCTACACCACTGTGCTGTTTGCCAACATCTACCTGGCTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAAT
TTCACTCTTCAGGGCTGCAGTTCCTCACACAGGCAGGAAGAACCAGGAGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAA
GATGCTCCTGATTGTGGCCCTGCTTTTTATTCTCTCATGGCTGCCCCTGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCC
AAATGAACTGCAGATCATCAACATCTACATCTACCCTTTTGCACACTGGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGG
TTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAAGAAGCTTTCCAGCTCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGC
CCTAAAAGCTAAAAGCCATGTGCTCATAAACACATCTAATCAGCTTGTCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCT

>In-frame_HS6ST2_ENST00000370833_chrX_132090836_-_NPFFR2_ENST00000344413_chr4_73003757_+_609nt
ATGGATGAGAAATCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCTTCCTATTTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACA
GAATGCCAGCTCCTCCGCCTGCAGGCGTTCAGCTCCCCGGTGCCGGACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCC
CGCTACAATTTCACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCGACATCAAGGGCGATGACCTGATCGTGTTCCTGCACATCCAGAAG
ACCGGGGGCACCACTTTCGGCCGCCACTTGGTGCGTAACATCCAGCTGGAGCAGCCGTGCGAGTGCCGCGTGGGTCAGAAGAAATGCACT
TGCCACCGGCCGGGTAAGCGGGAAACCTGGCTCTTCTCCAGGTTCTCCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTC
ACCAGCTGTGTGCCCTCCGTGGTGGACGGCAAGCGCGACGCCAGGCTGAGACCGTCCAGGATGGCCATTTGGAAACACGATGTGCAAGAT


* Fusion transcript sequences (Full-length transcript).
>In-frame_HS6ST2_ENST00000370836_chrX_132090836_-_NPFFR2_ENST00000308744_chr4_73003757_+_2553nt
AAGCCAGGCTGACCTTTATGCTCCCAGAATCATCAGCCTTTTCATTGGAAACCATGGAAGGACGGTTCTGGGAAAATAATGAAAATCATA
CCACACCATAGAGACAACCAGAAGCCCTGCTCAGATGACAGAGTTCTCCTCGCCTTCCAGAAAATGCCCCCGCTTCCGCTGGAGAATGGA
AATTGGCAAAGAGAGACGGAAAAGCTCCAATTTGCGCCTTTGCTATTTTAGGAGAGGTTGAAATTACGAGCCAAAGTGGAGTGATGCGCT
AAGCGGAGTGACCTCCGTACTCCAAGAAAAGAGAAAACCCAGGTTCTCTGCTTGTGAAGTGGCTCGAGCTCTTAGGCGTGAGGCATTATT
ATATAAATTCAAGCTCGCTCGTGATCCTTAGTACCCTGAGTTGCCTGAAGGGGGGAATGGCACTGCCTGCGTGTGCAGTCCGGGAGTTCG
AGCCGCCGCGGCAACCGGAGCGAGGAGCGCCCGTCCGCACCACCTGTCCCCGCCGGCATTCCAGAGTAGAGGCCGAATTGGCAGCGAGCC
GGCCCGGGTCGGTCGCCGCCTCAGTTCGCGCGGGCCCTCCTAGGGGTGTGTCTCACGGATTCCACACCCGGCCGCTCCTGGACAAGCCCC
GAAAGGCGTCTTCTTCCCTGGCGGGAGCCGCGTGCGCCCCGCTTTTCGCGCTGCTGTCCCGGGGCCGCCGCAGGCGGATGCACGTCCTCA
GGCGACGCTGGGACCTGGGCTCCCTCTGCCGGGCCCTGCTCACTCGGGGCCTGGCCGCCCTGGGCCACTCGCTGAAGCACGTGCTCGGTG
CGATCTTCTCCAAGATTTTCGGCCCCATGGCCAGCGTCGGGAACATGGATGAGAAATCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCT
TCCTATTTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACAGAATGCCAGCTCCTCCGCCTGCAGGCGTTCAGCTCCCCGGTGCCGG
ACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCCCGCTACAATTTCACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCG
ACATCAAGGGCGATGACCTGATCGTGTTCCTGCACATCCAGAAGACCGGGGGCACCACTTTCGGCCGCCACTTGGTGCGTAACATCCAGC
TGGAGCAGCCGTGCGAGTGCCGCGTGGGTCAGAAGAAATGCACTTGCCACCGGCCGGGTAAGCGGGAAACCTGGCTCTTCTCCAGGTTCT
CCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTCACCAGCTGTGTGCCCTCCGTGGTGGACGGCAAGCGCGACGCCAGGC
TGAGACCGTCCAGGATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGTCCAGGGAATATCTGTCGCAGCTTCAGTCTTTACG
TTAGTTGCAATTGCTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAAGCTCACTATCAAGACAGCGTTTGTCATTATTATG
ATCATCTGGGTCCTAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGTGCAAGAAGAAAAATATTACCGAGTGAGACTCAAC
TCCCAGAATAAAACCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGAAATGAGGAAGATCTACACCACTGTGCTGTTTGCC
AACATCTACCTGGCTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAATTTCACTCTTCAGGGCTGCAGTTCCTCACACAGGC
AGGAAGAACCAGGAGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAAGATGCTCCTGATTGTGGCCCTGCTTTTTATTCTC
TCATGGCTGCCCCTGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCCAAATGAACTGCAGATCATCAACATCTACATCTAC
CCTTTTGCACACTGGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGGTTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAA
GAAGCTTTCCAGCTCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGCCCTAAAAGCTAAAAGCCATGTGCTCATAAACACA
TCTAATCAGCTTGTCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCTTTATAGGAAAAGTGCTGAAAAACCCCAACAGGAA
TTAGTGATGGAAGAATTAAAAGAAACTACTAACAGCAGTGAGATTTAAAAAGAGCTAGTGTGATAATCCTAACTCTACTACGCATTATAT
ATTTAAATCCATTGCTTTTTGTGGCTTTGCACTTCAAATTTTTCAAAGAATGTTCTAAATAAAACATTTACTGAAAGCCCTCTCTGGCAA
AAAAATTAAAAATAAACAAAAATGGTCATAAGATCATAAACAATCTTATGTTGTATAAAAATACGTAGAGTGACTTAGACATGTTTGCAT

>In-frame_HS6ST2_ENST00000370836_chrX_132090836_-_NPFFR2_ENST00000395999_chr4_73003757_+_2547nt
AAGCCAGGCTGACCTTTATGCTCCCAGAATCATCAGCCTTTTCATTGGAAACCATGGAAGGACGGTTCTGGGAAAATAATGAAAATCATA
CCACACCATAGAGACAACCAGAAGCCCTGCTCAGATGACAGAGTTCTCCTCGCCTTCCAGAAAATGCCCCCGCTTCCGCTGGAGAATGGA
AATTGGCAAAGAGAGACGGAAAAGCTCCAATTTGCGCCTTTGCTATTTTAGGAGAGGTTGAAATTACGAGCCAAAGTGGAGTGATGCGCT
AAGCGGAGTGACCTCCGTACTCCAAGAAAAGAGAAAACCCAGGTTCTCTGCTTGTGAAGTGGCTCGAGCTCTTAGGCGTGAGGCATTATT
ATATAAATTCAAGCTCGCTCGTGATCCTTAGTACCCTGAGTTGCCTGAAGGGGGGAATGGCACTGCCTGCGTGTGCAGTCCGGGAGTTCG
AGCCGCCGCGGCAACCGGAGCGAGGAGCGCCCGTCCGCACCACCTGTCCCCGCCGGCATTCCAGAGTAGAGGCCGAATTGGCAGCGAGCC
GGCCCGGGTCGGTCGCCGCCTCAGTTCGCGCGGGCCCTCCTAGGGGTGTGTCTCACGGATTCCACACCCGGCCGCTCCTGGACAAGCCCC
GAAAGGCGTCTTCTTCCCTGGCGGGAGCCGCGTGCGCCCCGCTTTTCGCGCTGCTGTCCCGGGGCCGCCGCAGGCGGATGCACGTCCTCA
GGCGACGCTGGGACCTGGGCTCCCTCTGCCGGGCCCTGCTCACTCGGGGCCTGGCCGCCCTGGGCCACTCGCTGAAGCACGTGCTCGGTG
CGATCTTCTCCAAGATTTTCGGCCCCATGGCCAGCGTCGGGAACATGGATGAGAAATCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCT
TCCTATTTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACAGAATGCCAGCTCCTCCGCCTGCAGGCGTTCAGCTCCCCGGTGCCGG
ACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCCCGCTACAATTTCACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCG
ACATCAAGGGCGATGACCTGATCGTGTTCCTGCACATCCAGAAGACCGGGGGCACCACTTTCGGCCGCCACTTGGTGCGTAACATCCAGC
TGGAGCAGCCGTGCGAGTGCCGCGTGGGTCAGAAGAAATGCACTTGCCACCGGCCGGGTAAGCGGGAAACCTGGCTCTTCTCCAGGTTCT
CCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTCACCAGCTGTGTGCCCTCCGTGGTGGACGGCAAGCGCGACGCCAGGC
TGAGACCGTCCAGGATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGTCCAGGGAATATCTGTCGCAGCTTCAGTCTTTACG
TTAGTTGCAATTGCTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAAGCTCACTATCAAGACAGCGTTTGTCATTATTATG
ATCATCTGGGTCCTAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGTGCAAGAAGAAAAATATTACCGAGTGAGACTCAAC
TCCCAGAATAAAACCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGAAATGAGGAAGATCTACACCACTGTGCTGTTTGCC
AACATCTACCTGGCTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAATTTCACTCTTCAGGGCTGCAGTTCCTCACACAGGC
AGGAAGAACCAGGAGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAAGATGCTCCTGATTGTGGCCCTGCTTTTTATTCTC
TCATGGCTGCCCCTGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCCAAATGAACTGCAGATCATCAACATCTACATCTAC
CCTTTTGCACACTGGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGGTTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAA
GAAGCTTTCCAGCTCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGCCCTAAAAGCTAAAAGCCATGTGCTCATAAACACA
TCTAATCAGCTTGTCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCTTTATAGGAAAAGTGCTGAAAAACCCCAACAGGAA
TTAGTGATGGAAGAATTAAAAGAAACTACTAACAGCAGTGAGATTTAAAAAGAGCTAGTGTGATAATCCTAACTCTACTACGCATTATAT
ATTTAAATCCATTGCTTTTTGTGGCTTTGCACTTCAAATTTTTCAAAGAATGTTCTAAATAAAACATTTACTGAAAGCCCTCTCTGGCAA
AAAAATTAAAAATAAACAAAAATGGTCATAAGATCATAAACAATCTTATGTTGTATAAAAATACGTAGAGTGACTTAGACATGTTTGCAT

>In-frame_HS6ST2_ENST00000370836_chrX_132090836_-_NPFFR2_ENST00000358749_chr4_73003757_+_2547nt
AAGCCAGGCTGACCTTTATGCTCCCAGAATCATCAGCCTTTTCATTGGAAACCATGGAAGGACGGTTCTGGGAAAATAATGAAAATCATA
CCACACCATAGAGACAACCAGAAGCCCTGCTCAGATGACAGAGTTCTCCTCGCCTTCCAGAAAATGCCCCCGCTTCCGCTGGAGAATGGA
AATTGGCAAAGAGAGACGGAAAAGCTCCAATTTGCGCCTTTGCTATTTTAGGAGAGGTTGAAATTACGAGCCAAAGTGGAGTGATGCGCT
AAGCGGAGTGACCTCCGTACTCCAAGAAAAGAGAAAACCCAGGTTCTCTGCTTGTGAAGTGGCTCGAGCTCTTAGGCGTGAGGCATTATT
ATATAAATTCAAGCTCGCTCGTGATCCTTAGTACCCTGAGTTGCCTGAAGGGGGGAATGGCACTGCCTGCGTGTGCAGTCCGGGAGTTCG
AGCCGCCGCGGCAACCGGAGCGAGGAGCGCCCGTCCGCACCACCTGTCCCCGCCGGCATTCCAGAGTAGAGGCCGAATTGGCAGCGAGCC
GGCCCGGGTCGGTCGCCGCCTCAGTTCGCGCGGGCCCTCCTAGGGGTGTGTCTCACGGATTCCACACCCGGCCGCTCCTGGACAAGCCCC
GAAAGGCGTCTTCTTCCCTGGCGGGAGCCGCGTGCGCCCCGCTTTTCGCGCTGCTGTCCCGGGGCCGCCGCAGGCGGATGCACGTCCTCA
GGCGACGCTGGGACCTGGGCTCCCTCTGCCGGGCCCTGCTCACTCGGGGCCTGGCCGCCCTGGGCCACTCGCTGAAGCACGTGCTCGGTG
CGATCTTCTCCAAGATTTTCGGCCCCATGGCCAGCGTCGGGAACATGGATGAGAAATCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCT
TCCTATTTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACAGAATGCCAGCTCCTCCGCCTGCAGGCGTTCAGCTCCCCGGTGCCGG
ACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCCCGCTACAATTTCACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCG
ACATCAAGGGCGATGACCTGATCGTGTTCCTGCACATCCAGAAGACCGGGGGCACCACTTTCGGCCGCCACTTGGTGCGTAACATCCAGC
TGGAGCAGCCGTGCGAGTGCCGCGTGGGTCAGAAGAAATGCACTTGCCACCGGCCGGGTAAGCGGGAAACCTGGCTCTTCTCCAGGTTCT
CCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTCACCAGCTGTGTGCCCTCCGTGGTGGACGGCAAGCGCGACGCCAGGC
TGAGACCGTCCAGGATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGTCCAGGGAATATCTGTCGCAGCTTCAGTCTTTACG
TTAGTTGCAATTGCTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAAGCTCACTATCAAGACAGCGTTTGTCATTATTATG
ATCATCTGGGTCCTAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGTGCAAGAAGAAAAATATTACCGAGTGAGACTCAAC
TCCCAGAATAAAACCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGAAATGAGGAAGATCTACACCACTGTGCTGTTTGCC
AACATCTACCTGGCTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAATTTCACTCTTCAGGGCTGCAGTTCCTCACACAGGC
AGGAAGAACCAGGAGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAAGATGCTCCTGATTGTGGCCCTGCTTTTTATTCTC
TCATGGCTGCCCCTGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCCAAATGAACTGCAGATCATCAACATCTACATCTAC
CCTTTTGCACACTGGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGGTTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAA
GAAGCTTTCCAGCTCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGCCCTAAAAGCTAAAAGCCATGTGCTCATAAACACA
TCTAATCAGCTTGTCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCTTTATAGGAAAAGTGCTGAAAAACCCCAACAGGAA
TTAGTGATGGAAGAATTAAAAGAAACTACTAACAGCAGTGAGATTTAAAAAGAGCTAGTGTGATAATCCTAACTCTACTACGCATTATAT
ATTTAAATCCATTGCTTTTTGTGGCTTTGCACTTCAAATTTTTCAAAGAATGTTCTAAATAAAACATTTACTGAAAGCCCTCTCTGGCAA
AAAAATTAAAAATAAACAAAAATGGTCATAAGATCATAAACAATCTTATGTTGTATAAAAATACGTAGAGTGACTTAGACATGTTTGCAT

>In-frame_HS6ST2_ENST00000521489_chrX_132090836_-_NPFFR2_ENST00000308744_chr4_73003757_+_2553nt
AAGCCAGGCTGACCTTTATGCTCCCAGAATCATCAGCCTTTTCATTGGAAACCATGGAAGGACGGTTCTGGGAAAATAATGAAAATCATA
CCACACCATAGAGACAACCAGAAGCCCTGCTCAGATGACAGAGTTCTCCTCGCCTTCCAGAAAATGCCCCCGCTTCCGCTGGAGAATGGA
AATTGGCAAAGAGAGACGGAAAAGCTCCAATTTGCGCCTTTGCTATTTTAGGAGAGGTTGAAATTACGAGCCAAAGTGGAGTGATGCGCT
AAGCGGAGTGACCTCCGTACTCCAAGAAAAGAGAAAACCCAGGTTCTCTGCTTGTGAAGTGGCTCGAGCTCTTAGGCGTGAGGCATTATT
ATATAAATTCAAGCTCGCTCGTGATCCTTAGTACCCTGAGTTGCCTGAAGGGGGGAATGGCACTGCCTGCGTGTGCAGTCCGGGAGTTCG
AGCCGCCGCGGCAACCGGAGCGAGGAGCGCCCGTCCGCACCACCTGTCCCCGCCGGCATTCCAGAGTAGAGGCCGAATTGGCAGCGAGCC
GGCCCGGGTCGGTCGCCGCCTCAGTTCGCGCGGGCCCTCCTAGGGGTGTGTCTCACGGATTCCACACCCGGCCGCTCCTGGACAAGCCCC
GAAAGGCGTCTTCTTCCCTGGCGGGAGCCGCGTGCGCCCCGCTTTTCGCGCTGCTGTCCCGGGGCCGCCGCAGGCGGATGCACGTCCTCA
GGCGACGCTGGGACCTGGGCTCCCTCTGCCGGGCCCTGCTCACTCGGGGCCTGGCCGCCCTGGGCCACTCGCTGAAGCACGTGCTCGGTG
CGATCTTCTCCAAGATTTTCGGCCCCATGGCCAGCGTCGGGAACATGGATGAGAAATCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCT
TCCTATTTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACAGAATGCCAGCTCCTCCGCCTGCAGGCGTTCAGCTCCCCGGTGCCGG
ACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCCCGCTACAATTTCACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCG
ACATCAAGGGCGATGACCTGATCGTGTTCCTGCACATCCAGAAGACCGGGGGCACCACTTTCGGCCGCCACTTGGTGCGTAACATCCAGC
TGGAGCAGCCGTGCGAGTGCCGCGTGGGTCAGAAGAAATGCACTTGCCACCGGCCGGGTAAGCGGGAAACCTGGCTCTTCTCCAGGTTCT
CCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTCACCAGCTGTGTGCCCTCCGTGGTGGACGGCAAGCGCGACGCCAGGC
TGAGACCGTCCAGGATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGTCCAGGGAATATCTGTCGCAGCTTCAGTCTTTACG
TTAGTTGCAATTGCTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAAGCTCACTATCAAGACAGCGTTTGTCATTATTATG
ATCATCTGGGTCCTAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGTGCAAGAAGAAAAATATTACCGAGTGAGACTCAAC
TCCCAGAATAAAACCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGAAATGAGGAAGATCTACACCACTGTGCTGTTTGCC
AACATCTACCTGGCTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAATTTCACTCTTCAGGGCTGCAGTTCCTCACACAGGC
AGGAAGAACCAGGAGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAAGATGCTCCTGATTGTGGCCCTGCTTTTTATTCTC
TCATGGCTGCCCCTGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCCAAATGAACTGCAGATCATCAACATCTACATCTAC
CCTTTTGCACACTGGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGGTTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAA
GAAGCTTTCCAGCTCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGCCCTAAAAGCTAAAAGCCATGTGCTCATAAACACA
TCTAATCAGCTTGTCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCTTTATAGGAAAAGTGCTGAAAAACCCCAACAGGAA
TTAGTGATGGAAGAATTAAAAGAAACTACTAACAGCAGTGAGATTTAAAAAGAGCTAGTGTGATAATCCTAACTCTACTACGCATTATAT
ATTTAAATCCATTGCTTTTTGTGGCTTTGCACTTCAAATTTTTCAAAGAATGTTCTAAATAAAACATTTACTGAAAGCCCTCTCTGGCAA
AAAAATTAAAAATAAACAAAAATGGTCATAAGATCATAAACAATCTTATGTTGTATAAAAATACGTAGAGTGACTTAGACATGTTTGCAT

>In-frame_HS6ST2_ENST00000521489_chrX_132090836_-_NPFFR2_ENST00000395999_chr4_73003757_+_2547nt
AAGCCAGGCTGACCTTTATGCTCCCAGAATCATCAGCCTTTTCATTGGAAACCATGGAAGGACGGTTCTGGGAAAATAATGAAAATCATA
CCACACCATAGAGACAACCAGAAGCCCTGCTCAGATGACAGAGTTCTCCTCGCCTTCCAGAAAATGCCCCCGCTTCCGCTGGAGAATGGA
AATTGGCAAAGAGAGACGGAAAAGCTCCAATTTGCGCCTTTGCTATTTTAGGAGAGGTTGAAATTACGAGCCAAAGTGGAGTGATGCGCT
AAGCGGAGTGACCTCCGTACTCCAAGAAAAGAGAAAACCCAGGTTCTCTGCTTGTGAAGTGGCTCGAGCTCTTAGGCGTGAGGCATTATT
ATATAAATTCAAGCTCGCTCGTGATCCTTAGTACCCTGAGTTGCCTGAAGGGGGGAATGGCACTGCCTGCGTGTGCAGTCCGGGAGTTCG
AGCCGCCGCGGCAACCGGAGCGAGGAGCGCCCGTCCGCACCACCTGTCCCCGCCGGCATTCCAGAGTAGAGGCCGAATTGGCAGCGAGCC
GGCCCGGGTCGGTCGCCGCCTCAGTTCGCGCGGGCCCTCCTAGGGGTGTGTCTCACGGATTCCACACCCGGCCGCTCCTGGACAAGCCCC
GAAAGGCGTCTTCTTCCCTGGCGGGAGCCGCGTGCGCCCCGCTTTTCGCGCTGCTGTCCCGGGGCCGCCGCAGGCGGATGCACGTCCTCA
GGCGACGCTGGGACCTGGGCTCCCTCTGCCGGGCCCTGCTCACTCGGGGCCTGGCCGCCCTGGGCCACTCGCTGAAGCACGTGCTCGGTG
CGATCTTCTCCAAGATTTTCGGCCCCATGGCCAGCGTCGGGAACATGGATGAGAAATCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCT
TCCTATTTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACAGAATGCCAGCTCCTCCGCCTGCAGGCGTTCAGCTCCCCGGTGCCGG
ACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCCCGCTACAATTTCACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCG
ACATCAAGGGCGATGACCTGATCGTGTTCCTGCACATCCAGAAGACCGGGGGCACCACTTTCGGCCGCCACTTGGTGCGTAACATCCAGC
TGGAGCAGCCGTGCGAGTGCCGCGTGGGTCAGAAGAAATGCACTTGCCACCGGCCGGGTAAGCGGGAAACCTGGCTCTTCTCCAGGTTCT
CCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTCACCAGCTGTGTGCCCTCCGTGGTGGACGGCAAGCGCGACGCCAGGC
TGAGACCGTCCAGGATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGTCCAGGGAATATCTGTCGCAGCTTCAGTCTTTACG
TTAGTTGCAATTGCTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAAGCTCACTATCAAGACAGCGTTTGTCATTATTATG
ATCATCTGGGTCCTAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGTGCAAGAAGAAAAATATTACCGAGTGAGACTCAAC
TCCCAGAATAAAACCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGAAATGAGGAAGATCTACACCACTGTGCTGTTTGCC
AACATCTACCTGGCTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAATTTCACTCTTCAGGGCTGCAGTTCCTCACACAGGC
AGGAAGAACCAGGAGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAAGATGCTCCTGATTGTGGCCCTGCTTTTTATTCTC
TCATGGCTGCCCCTGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCCAAATGAACTGCAGATCATCAACATCTACATCTAC
CCTTTTGCACACTGGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGGTTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAA
GAAGCTTTCCAGCTCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGCCCTAAAAGCTAAAAGCCATGTGCTCATAAACACA
TCTAATCAGCTTGTCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCTTTATAGGAAAAGTGCTGAAAAACCCCAACAGGAA
TTAGTGATGGAAGAATTAAAAGAAACTACTAACAGCAGTGAGATTTAAAAAGAGCTAGTGTGATAATCCTAACTCTACTACGCATTATAT
ATTTAAATCCATTGCTTTTTGTGGCTTTGCACTTCAAATTTTTCAAAGAATGTTCTAAATAAAACATTTACTGAAAGCCCTCTCTGGCAA
AAAAATTAAAAATAAACAAAAATGGTCATAAGATCATAAACAATCTTATGTTGTATAAAAATACGTAGAGTGACTTAGACATGTTTGCAT

>In-frame_HS6ST2_ENST00000521489_chrX_132090836_-_NPFFR2_ENST00000358749_chr4_73003757_+_2547nt
AAGCCAGGCTGACCTTTATGCTCCCAGAATCATCAGCCTTTTCATTGGAAACCATGGAAGGACGGTTCTGGGAAAATAATGAAAATCATA
CCACACCATAGAGACAACCAGAAGCCCTGCTCAGATGACAGAGTTCTCCTCGCCTTCCAGAAAATGCCCCCGCTTCCGCTGGAGAATGGA
AATTGGCAAAGAGAGACGGAAAAGCTCCAATTTGCGCCTTTGCTATTTTAGGAGAGGTTGAAATTACGAGCCAAAGTGGAGTGATGCGCT
AAGCGGAGTGACCTCCGTACTCCAAGAAAAGAGAAAACCCAGGTTCTCTGCTTGTGAAGTGGCTCGAGCTCTTAGGCGTGAGGCATTATT
ATATAAATTCAAGCTCGCTCGTGATCCTTAGTACCCTGAGTTGCCTGAAGGGGGGAATGGCACTGCCTGCGTGTGCAGTCCGGGAGTTCG
AGCCGCCGCGGCAACCGGAGCGAGGAGCGCCCGTCCGCACCACCTGTCCCCGCCGGCATTCCAGAGTAGAGGCCGAATTGGCAGCGAGCC
GGCCCGGGTCGGTCGCCGCCTCAGTTCGCGCGGGCCCTCCTAGGGGTGTGTCTCACGGATTCCACACCCGGCCGCTCCTGGACAAGCCCC
GAAAGGCGTCTTCTTCCCTGGCGGGAGCCGCGTGCGCCCCGCTTTTCGCGCTGCTGTCCCGGGGCCGCCGCAGGCGGATGCACGTCCTCA
GGCGACGCTGGGACCTGGGCTCCCTCTGCCGGGCCCTGCTCACTCGGGGCCTGGCCGCCCTGGGCCACTCGCTGAAGCACGTGCTCGGTG
CGATCTTCTCCAAGATTTTCGGCCCCATGGCCAGCGTCGGGAACATGGATGAGAAATCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCT
TCCTATTTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACAGAATGCCAGCTCCTCCGCCTGCAGGCGTTCAGCTCCCCGGTGCCGG
ACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCCCGCTACAATTTCACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCG
ACATCAAGGGCGATGACCTGATCGTGTTCCTGCACATCCAGAAGACCGGGGGCACCACTTTCGGCCGCCACTTGGTGCGTAACATCCAGC
TGGAGCAGCCGTGCGAGTGCCGCGTGGGTCAGAAGAAATGCACTTGCCACCGGCCGGGTAAGCGGGAAACCTGGCTCTTCTCCAGGTTCT
CCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTCACCAGCTGTGTGCCCTCCGTGGTGGACGGCAAGCGCGACGCCAGGC
TGAGACCGTCCAGGATGGCCATTTGGAAACACGATGTGCAAGATCAGTGGATTGGTCCAGGGAATATCTGTCGCAGCTTCAGTCTTTACG
TTAGTTGCAATTGCTGTAGATAGGTTCCAGTGTGTGGTCTACCCTTTTAAACCAAAGCTCACTATCAAGACAGCGTTTGTCATTATTATG
ATCATCTGGGTCCTAGCCATCACCATTATGTCTCCATCTGCAGTAATGTTACATGTGCAAGAAGAAAAATATTACCGAGTGAGACTCAAC
TCCCAGAATAAAACCAGTCCAGTCTACTGGTGCCGGGAAGACTGGCCAAATCAGGAAATGAGGAAGATCTACACCACTGTGCTGTTTGCC
AACATCTACCTGGCTCCCCTCTCCCTCATTGTCATCATGTATGGAAGGATTGGAATTTCACTCTTCAGGGCTGCAGTTCCTCACACAGGC
AGGAAGAACCAGGAGCAGTGGCACGTGGTGTCCAGGAAGAAGCAGAAGATCATTAAGATGCTCCTGATTGTGGCCCTGCTTTTTATTCTC
TCATGGCTGCCCCTGTGGACTCTAATGATGCTCTCAGACTACGCTGACCTTTCTCCAAATGAACTGCAGATCATCAACATCTACATCTAC
CCTTTTGCACACTGGCTGGCATTCGGCAACAGCAGTGTCAATCCCATCATTTATGGTTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAA
GAAGCTTTCCAGCTCCAGCTCTGCCAAAAAAGAGCAAAGCCTATGGAAGCTTATGCCCTAAAAGCTAAAAGCCATGTGCTCATAAACACA
TCTAATCAGCTTGTCCAGGAATCTACATTTCAAAACCCTCATGGGGAAACCTTGCTTTATAGGAAAAGTGCTGAAAAACCCCAACAGGAA
TTAGTGATGGAAGAATTAAAAGAAACTACTAACAGCAGTGAGATTTAAAAAGAGCTAGTGTGATAATCCTAACTCTACTACGCATTATAT
ATTTAAATCCATTGCTTTTTGTGGCTTTGCACTTCAAATTTTTCAAAGAATGTTCTAAATAAAACATTTACTGAAAGCCCTCTCTGGCAA
AAAAATTAAAAATAAACAAAAATGGTCATAAGATCATAAACAATCTTATGTTGTATAAAAATACGTAGAGTGACTTAGACATGTTTGCAT

>In-frame_HS6ST2_ENST00000370833_chrX_132090836_-_NPFFR2_ENST00000344413_chr4_73003757_+_1444nt
ATGGATGAGAAATCCAACAAGCTGCTGCTAGCTTTGGTGATGCTCTTCCTATTTGCCGTGATCGTCCTCCAATACGTGTGCCCCGGCACA
GAATGCCAGCTCCTCCGCCTGCAGGCGTTCAGCTCCCCGGTGCCGGACCCGTACCGCTCGGAGGATGAGAGCTCCGCCAGGTTCGTGCCC
CGCTACAATTTCACCCGCGGCGACCTCCTGCGCAAGGTAGACTTCGACATCAAGGGCGATGACCTGATCGTGTTCCTGCACATCCAGAAG
ACCGGGGGCACCACTTTCGGCCGCCACTTGGTGCGTAACATCCAGCTGGAGCAGCCGTGCGAGTGCCGCGTGGGTCAGAAGAAATGCACT
TGCCACCGGCCGGGTAAGCGGGAAACCTGGCTCTTCTCCAGGTTCTCCACGGGCTGGAGCTGCGGGTTGCACGCCGACTGGACCGAGCTC
ACCAGCTGTGTGCCCTCCGTGGTGGACGGCAAGCGCGACGCCAGGCTGAGACCGTCCAGGATGGCCATTTGGAAACACGATGTGCAAGAT
CAGTGGATTGGTCCAGGGAATATCTGTCGCAGCTTCAGTCTTTACGTTAGTTGCAATTGCTGTAGATAGGTTCCAGTGTGTGGTCTACCC
TTTTAAACCAAAGCTCACTATCAAGACAGCGTTTGTCATTATTATGATCATCTGGGTCCTAGCCATCACCATTATGTCTCCATCTGCAGT
AATGTTACATGTGCAAGAAGAAAAATATTACCGAGTGAGACTCAACTCCCAGAATAAAACCAGTCCAGTCTACTGGTGCCGGGAAGACTG
GCCAAATCAGGAAATGAGGAAGATCTACACCACTGTGCTGTTTGCCAACATCTACCTGGCTCCCCTCTCCCTCATTGTCATCATGTATGG
AAGGATTGGAATTTCACTCTTCAGGGCTGCAGTTCCTCACACAGGCAGGAAGAACCAGGAGCAGTGGCACGTGGTGTCCAGGAAGAAGCA
GAAGATCATTAAGATGCTCCTGATTGTGGCCCTGCTTTTTATTCTCTCATGGCTGCCCCTGTGGACTCTAATGATGCTCTCAGACTACGC
TGACCTTTCTCCAAATGAACTGCAGATCATCAACATCTACATCTACCCTTTTGCACACTGGCTGGCATTCGGCAACAGCAGTGTCAATCC
CATCATTTATGGTTTCTTCAACGAGAATTTCCGCCGTGGTTTCCAAGAAGCTTTCCAGCTCCAGCTCTGCCAAAAAAGAGCAAAGCCTAT
GGAAGCTTATGCCCTAAAAGCTAAAAGCCATGTGCTCATAAACACATCTAATCAGCTTGTCCAGGAATCTACATTTCAAAACCCTCATGG
GGAAACCTTGCTTTATAGGAAAAGTGCTGAAAAACCCCAACAGGAATTAGTGATGGAAGAATTAAAAGAAACTACTAACAGCAGTGAGAT


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FusionGenePPI for HS6ST2_NPFFR2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
HS6ST2GINM1, CHST10, PTCH1, TNF, YWHAZ, KIF20A, NETO2NPFFR2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for HS6ST2_NPFFR2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for HS6ST2_NPFFR2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource