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Fusion gene ID: 16684 |
FusionGeneSummary for HOOK3_TGS1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HOOK3_TGS1 | Fusion gene ID: 16684 | Hgene | Tgene | Gene symbol | HOOK3 | TGS1 | Gene ID | 84376 | 286826 |
| Gene name | hook microtubule tethering protein 3 | lin-9 DREAM MuvB core complex component | |
| Synonyms | HK3 | BARA|BARPsv|Lin-9|TGS|TGS1|TGS2 | |
| Cytomap | 8p11.21 | 1q42.12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein Hook homolog 3h-hook3hHK3hook homolog 3 | protein lin-9 homologTUDOR gene similar proteinbeta subunit-associated regulator of apoptosislin-9 homologpRB-associated proteinrb related pathway actortype I interferon receptor beta chain-associated protein | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q86VS8 | Q96RS0 | |
| Ensembl transtripts involved in fusion gene | ENST00000307602, ENST00000524839, | ENST00000260129, | |
| Fusion gene scores | * DoF score | 11 X 10 X 6=660 | 3 X 4 X 3=36 |
| # samples | 15 | 3 | |
| ** MAII score | log2(15/660*10)=-2.13750352374993 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/36*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: HOOK3 [Title/Abstract] AND TGS1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-CA-6715-01A | HOOK3 | chr8 | 42761401 | + | TGS1 | chr8 | 56695307 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000307602 | ENST00000260129 | HOOK3 | chr8 | 42761401 | + | TGS1 | chr8 | 56695307 | + |
| intron-3CDS | ENST00000524839 | ENST00000260129 | HOOK3 | chr8 | 42761401 | + | TGS1 | chr8 | 56695307 | + |
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FusionProtFeatures for HOOK3_TGS1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HOOK3 | TGS1 |
| Probably serves as a target for the spiC protein fromSalmonella typhimurium, which inactivates it, leading to a strongalteration in cellular trafficking (By similarity). Component ofthe FTS/Hook/FHIP complex (FHF complex). The FHF complex mayfunction to promote vesicle trafficking and/or fusion via thehomotypic vesicular protein sorting complex (the HOPS complex).May regulate clearance of endocytosed receptors such as MSR1.Participates in defining the architecture and localization of theGolgi complex. Acts as an adapter protein linking the dynein motorcomplex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence ofdynactin. Facilitates the interaction between dynein and dynactinand activates dynein processivity (the ability to move along amicrotubule for a long distance without falling off the track)(PubMed:25035494). {ECO:0000250|UniProtKB:Q8BUK6,ECO:0000269|PubMed:11238449, ECO:0000269|PubMed:17237231,ECO:0000269|PubMed:18799622, ECO:0000269|PubMed:25035494}. | Catalyzes the 2 serial methylation steps for theconversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs andsnoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure.The enzyme is specific for guanine, and N7 methylation mustprecede N2 methylation. Hypermethylation of the m7G cap of UsnRNAs leads to their concentration in nuclear foci, theircolocalization with coilin and the formation of canonical Cajalbodies (CBs). Plays a role in transcriptional regulation.{ECO:0000269|PubMed:11517327, ECO:0000269|PubMed:11912212,ECO:0000269|PubMed:16687569, ECO:0000269|PubMed:18775984}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >TGS1 | chr8:42761401 | chr8:56695307 | ENST00000260129 | + | 0 | 13 | 611_624 | 33 | 854 | Compositional bias | Note=Lys-rich |
| Tgene | >TGS1 | chr8:42761401 | chr8:56695307 | ENST00000260129 | + | 0 | 13 | 631_846 | 33 | 854 | Region | Note=Sufficient for catalytic activity |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >HOOK3 | chr8:42761401 | chr8:56695307 | ENST00000307602 | + | 2 | 22 | 167_433 | 47 | 719 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >HOOK3 | chr8:42761401 | chr8:56695307 | ENST00000307602 | + | 2 | 22 | 462_667 | 47 | 719 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >HOOK3 | chr8:42761401 | chr8:56695307 | ENST00000307602 | + | 2 | 22 | 10_126 | 47 | 719 | Domain | Calponin-homology (CH) |
| Hgene | >HOOK3 | chr8:42761401 | chr8:56695307 | ENST00000307602 | + | 2 | 22 | 553_718 | 47 | 719 | Region | Note=Required for association with Golgi |
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FusionGeneSequence for HOOK3_TGS1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_HOOK3_ENST00000307602_chr8_42761401_+_TGS1_ENST00000260129_chr8_56695307_+_868aa MFSVESLERAELCESLLTWIQTFNVDAPCQTVEDLTNGVVMAQVLQKMDRKLYNLGLKGYYIRDSGNNSGDQATEEEEGGYSCGTAESHD SKGIGLDESELDSEAELMRSMGLPLQFGRITAHKDFEVSMNTRNKVKIKKKKHQKKYLDEIVQESWRKEYEEDDILASDDPSSIEQYENT RTYELQSKKDTETENPPVENTLSPKLEITEKWEKYWNEYGGGLLWQSWQEKHPGQALSSEPWNFPDTKEEWEQHYSQLYWYYLEQFQYWE AQGWTFDASQSCDTDTYTSKTEADDKNDEKCMKVDLVSFPSSPIMVDNDSSGTSDKDHSEILDGISNIKLNSEEVTQSQLDSCTSHDGHQ QLSEVSSKRECPASGQSEPRNGGTNEESNSSGNTNTDPPAEDSQKSSGANTSKDRPHASGTDGDESEEDPPEHKPSKLKRSHELDIDENP ASDFDDSGSLLGFKYGSGQKYGGIPNFSHRQVRYLEKNVKLKSKYLDMRRQIKMKNKHIFFTKESEKPFFKKSKILSKVEKFLTWVNKPM DEEASQESSSHDNVHDASTSSDSEEQDMSVKKGDDLLETNNPEPEKCQSVSSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAETE AEVKKKKNKKKNKKVNGLPPEIAAVPELAKYWAQRYRLFSRFDDGIKLDREGWFSVTPEKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTI QFALTGMRVIAIDIDPVKIALARNNAEVYGIADKIEFICGDFLLLASFLKADVVFLSPPWGGPDYATAETFDIRTMMSPDGFEIFRLSKK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_HOOK3_ENST00000307602_chr8_42761401_+_TGS1_ENST00000260129_chr8_56695307_+_2604nt ATGTTCAGCGTAGAGTCGCTGGAGCGGGCGGAGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTAATGTGGATGCACCATGCCAG ACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATGGATCGAAAATTGTACAATTTGGGATTAAAAGGCTAT TACATCAGAGACAGTGGCAACAATTCAGGAGACCAGGCGACAGAAGAAGAGGAAGGTGGTTATTCCTGTGGTACTGCAGAATCACATGAC AGCAAAGGCATAGGCCTGGATGAAAGTGAACTTGATTCTGAGGCTGAACTCATGAGAAGTATGGGATTGCCACTTCAATTTGGTAGGATA ACTGCACATAAGGATTTTGAGGTATCTATGAATACTAGAAATAAAGTTAAAATAAAAAAGAAAAAACATCAAAAGAAATACTTAGATGAA ATTGTGCAAGAATCTTGGAGAAAAGAATATGAAGAAGACGACATTTTGGCTTCAGATGATCCATCTTCAATTGAACAGTATGAGAACACC AGAACATATGAACTTCAAAGCAAAAAAGATACTGAGACAGAAAATCCTCCAGTTGAAAACACATTATCTCCAAAGCTAGAAATTACAGAG AAATGGGAAAAGTATTGGAATGAATATGGAGGAGGACTATTGTGGCAAAGTTGGCAAGAAAAACATCCGGGTCAAGCACTATCTTCTGAA CCTTGGAACTTTCCTGATACAAAGGAAGAATGGGAGCAACATTATAGTCAACTTTATTGGTATTATTTGGAACAATTTCAGTATTGGGAA GCTCAGGGTTGGACTTTTGATGCCTCGCAAAGCTGTGATACAGATACTTACACATCTAAAACAGAAGCTGATGACAAGAACGATGAAAAA TGCATGAAAGTTGACTTAGTATCTTTTCCATCTTCACCTATTATGGTTGATAATGATAGCTCTGGTACAAGTGATAAGGATCATAGTGAA ATACTTGATGGAATTAGTAACATAAAACTGAATTCAGAGGAAGTAACACAGAGCCAATTAGATTCCTGTACAAGTCATGATGGTCATCAA CAGCTAAGTGAAGTTAGTAGCAAAAGAGAGTGCCCTGCTTCCGGCCAAAGTGAACCACGTAATGGAGGAACCAATGAGGAAAGCAACTCA TCGGGGAATACAAACACAGACCCACCAGCTGAGGATTCACAGAAGTCTTCAGGAGCAAACACAAGCAAAGACAGACCACATGCCAGTGGT ACTGATGGAGATGAAAGTGAGGAAGACCCACCTGAGCATAAGCCAAGCAAACTGAAGAGGAGCCATGAACTGGACATTGATGAAAACCCA GCTTCAGACTTTGATGACAGTGGTTCCCTTCTAGGATTCAAGTATGGCTCAGGACAAAAATATGGTGGAATCCCAAATTTCAGTCATCGG CAGGTCAGGTATTTAGAGAAGAATGTGAAGCTTAAGTCTAAGTACCTAGACATGCGCAGACAAATAAAGATGAAAAACAAACACATCTTC TTTACCAAAGAGTCAGAAAAACCATTTTTCAAGAAAAGCAAAATTCTGAGTAAGGTAGAAAAATTCCTCACATGGGTTAATAAACCAATG GATGAAGAAGCATCACAGGAATCATCTTCTCATGACAATGTGCACGACGCTTCCACAAGTAGTGATTCAGAGGAACAAGACATGTCTGTT AAAAAAGGTGATGACCTACTGGAGACTAATAATCCAGAACCTGAAAAGTGTCAGAGCGTATCTTCAGCTGGTGAACTTGAAACAGAAAAC TATGAAAGAGACAGCTTGCTAGCAACTGTTCCAGATGAGCAGGATTGTGTTACTCAAGAAGTGCCAGACTCCCGCCAGGCAGAAACTGAA GCTGAAGTGAAAAAGAAGAAGAACAAGAAGAAGAACAAAAAGGTGAATGGTCTGCCTCCTGAAATAGCTGCTGTTCCTGAGCTGGCAAAA TACTGGGCCCAGAGGTACAGGCTCTTCTCCCGTTTTGATGATGGGATTAAGTTGGACAGAGAGGGCTGGTTTTCAGTTACACCCGAGAAG ATTGCTGAACACATTGCTGGCCGTGTTAGTCAGTCCTTCAAGTGTGACGTTGTAGTAGACGCATTCTGTGGAGTTGGAGGAAATACCATT CAGTTTGCCTTAACAGGAATGAGAGTGATTGCCATTGATATCGATCCTGTTAAGATTGCCCTTGCTCGCAATAATGCAGAAGTTTATGGG ATAGCAGATAAGATAGAGTTCATCTGTGGAGATTTCTTGCTGCTGGCTTCTTTTTTAAAGGCTGATGTTGTGTTCCTCAGCCCACCTTGG GGAGGGCCAGACTATGCCACTGCAGAGACCTTTGACATTAGAACAATGATGTCTCCTGATGGCTTTGAAATTTTCAGACTTTCTAAGAAG ATCACTAATAATATTGTTTATTTTCTTCCAAGAAATGCTGATATTGACCAGGTGGCATCCTTAGCTGGGCCTGGAGGGCAAGTGGAAATA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_HOOK3_ENST00000307602_chr8_42761401_+_TGS1_ENST00000260129_chr8_56695307_+_3547nt CGGTCCCGAGTGAAAGGAGAAGGAGGGGCGCTGGGGGTGACGGTGCGGAGCCGCTGCCAGCGCTGGGCGAGAGTCGGCGGCCGGATCCGA GGAGCAGGCGGGCCTGAGGCCGAGTCAGCTGCGCGGGCCCCCGGATCCCCCGACAGAGCGGCGGCGGTGTCTGGCCAGGCGGTAGGCGCT GCCTGGCCGCGGCGGGGAAGATGTTCAGCGTAGAGTCGCTGGAGCGGGCGGAGCTGTGCGAGAGCCTCCTCACTTGGATCCAGACATTTA ATGTGGATGCACCATGCCAGACCGTGGAAGATTTAACGAATGGGGTTGTGATGGCCCAGGTTCTTCAAAAGATGGATCGAAAATTGTACA ATTTGGGATTAAAAGGCTATTACATCAGAGACAGTGGCAACAATTCAGGAGACCAGGCGACAGAAGAAGAGGAAGGTGGTTATTCCTGTG GTACTGCAGAATCACATGACAGCAAAGGCATAGGCCTGGATGAAAGTGAACTTGATTCTGAGGCTGAACTCATGAGAAGTATGGGATTGC CACTTCAATTTGGTAGGATAACTGCACATAAGGATTTTGAGGTATCTATGAATACTAGAAATAAAGTTAAAATAAAAAAGAAAAAACATC AAAAGAAATACTTAGATGAAATTGTGCAAGAATCTTGGAGAAAAGAATATGAAGAAGACGACATTTTGGCTTCAGATGATCCATCTTCAA TTGAACAGTATGAGAACACCAGAACATATGAACTTCAAAGCAAAAAAGATACTGAGACAGAAAATCCTCCAGTTGAAAACACATTATCTC CAAAGCTAGAAATTACAGAGAAATGGGAAAAGTATTGGAATGAATATGGAGGAGGACTATTGTGGCAAAGTTGGCAAGAAAAACATCCGG GTCAAGCACTATCTTCTGAACCTTGGAACTTTCCTGATACAAAGGAAGAATGGGAGCAACATTATAGTCAACTTTATTGGTATTATTTGG AACAATTTCAGTATTGGGAAGCTCAGGGTTGGACTTTTGATGCCTCGCAAAGCTGTGATACAGATACTTACACATCTAAAACAGAAGCTG ATGACAAGAACGATGAAAAATGCATGAAAGTTGACTTAGTATCTTTTCCATCTTCACCTATTATGGTTGATAATGATAGCTCTGGTACAA GTGATAAGGATCATAGTGAAATACTTGATGGAATTAGTAACATAAAACTGAATTCAGAGGAAGTAACACAGAGCCAATTAGATTCCTGTA CAAGTCATGATGGTCATCAACAGCTAAGTGAAGTTAGTAGCAAAAGAGAGTGCCCTGCTTCCGGCCAAAGTGAACCACGTAATGGAGGAA CCAATGAGGAAAGCAACTCATCGGGGAATACAAACACAGACCCACCAGCTGAGGATTCACAGAAGTCTTCAGGAGCAAACACAAGCAAAG ACAGACCACATGCCAGTGGTACTGATGGAGATGAAAGTGAGGAAGACCCACCTGAGCATAAGCCAAGCAAACTGAAGAGGAGCCATGAAC TGGACATTGATGAAAACCCAGCTTCAGACTTTGATGACAGTGGTTCCCTTCTAGGATTCAAGTATGGCTCAGGACAAAAATATGGTGGAA TCCCAAATTTCAGTCATCGGCAGGTCAGGTATTTAGAGAAGAATGTGAAGCTTAAGTCTAAGTACCTAGACATGCGCAGACAAATAAAGA TGAAAAACAAACACATCTTCTTTACCAAAGAGTCAGAAAAACCATTTTTCAAGAAAAGCAAAATTCTGAGTAAGGTAGAAAAATTCCTCA CATGGGTTAATAAACCAATGGATGAAGAAGCATCACAGGAATCATCTTCTCATGACAATGTGCACGACGCTTCCACAAGTAGTGATTCAG AGGAACAAGACATGTCTGTTAAAAAAGGTGATGACCTACTGGAGACTAATAATCCAGAACCTGAAAAGTGTCAGAGCGTATCTTCAGCTG GTGAACTTGAAACAGAAAACTATGAAAGAGACAGCTTGCTAGCAACTGTTCCAGATGAGCAGGATTGTGTTACTCAAGAAGTGCCAGACT CCCGCCAGGCAGAAACTGAAGCTGAAGTGAAAAAGAAGAAGAACAAGAAGAAGAACAAAAAGGTGAATGGTCTGCCTCCTGAAATAGCTG CTGTTCCTGAGCTGGCAAAATACTGGGCCCAGAGGTACAGGCTCTTCTCCCGTTTTGATGATGGGATTAAGTTGGACAGAGAGGGCTGGT TTTCAGTTACACCCGAGAAGATTGCTGAACACATTGCTGGCCGTGTTAGTCAGTCCTTCAAGTGTGACGTTGTAGTAGACGCATTCTGTG GAGTTGGAGGAAATACCATTCAGTTTGCCTTAACAGGAATGAGAGTGATTGCCATTGATATCGATCCTGTTAAGATTGCCCTTGCTCGCA ATAATGCAGAAGTTTATGGGATAGCAGATAAGATAGAGTTCATCTGTGGAGATTTCTTGCTGCTGGCTTCTTTTTTAAAGGCTGATGTTG TGTTCCTCAGCCCACCTTGGGGAGGGCCAGACTATGCCACTGCAGAGACCTTTGACATTAGAACAATGATGTCTCCTGATGGCTTTGAAA TTTTCAGACTTTCTAAGAAGATCACTAATAATATTGTTTATTTTCTTCCAAGAAATGCTGATATTGACCAGGTGGCATCCTTAGCTGGGC CTGGAGGGCAAGTGGAAATAGAACAGAACTTCCTTAACAACAAATTGAAGACAATCACTGCATATTTTGGTGACCTAATTCGAAGACCAG CCTCTGAAACCTAACTATGCAGCAGTGCGAGGACAAAAGATCATGGAGTGGTCAAAATATTCAGATGAGACATTTGGCATGTCTTCCTTT ATTCACTGATATTTTCTACCCATGGTCTTATATCACCGTATGAAATGGAAACTTACAGGACTTAAATATCAGTGAAATATTTTGAGATCT TTGAATAATTCCTTTAGAGGAATTATACAAAATTAATATATATGAGTCCTTTGTAATTTATTTTTTTTTGAGACAGGATCTCACTTTTAC CGCCCAGGCTGGAGTGCAGTGCCATGATCACAGCTCACTGCAGGTTCAGCCTTCTGAGTTCAAGCAATCCTTCTGTCTCAGTCTCCTCAG TAGCTGGGGCTTTAGGTGGGCACTGCCACACCGTACTAATTTTTGTATTTTTTGTAGAGACGAGGTCCCACCATGTTGCCCAGGCTGGTG TCAAACTCCTGGGCTCAGTCAGTCCCCCCATCTCACCCTCCCCAAGTGCTGGAATTACAGGCGTGAGCTACTGTGCCCAGCCTTACGGAC ATCCTTTTGAATTATCTTTTTCACTCATAGAATATGAATACATTTATTTAGACTTTTTCTAGAACTTTCCTGTTTTCATGTCTTTGCTTC ATCTGGAATTGGCTTAACACCCTTTTATAAAGTTTGTGTTTGTAAAATTTCCATTGTGACATCAATACGCAATATATTTTGTAATATAGG |
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FusionGenePPI for HOOK3_TGS1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| HOOK3 | CUL3, AKTIP, HOOK1, HOOK2, HOOK3, FAM160A2, VPS16, VPS41, SCFD1, CCDC8, ZC4H2, COMTD1, TNFSF13B, IFT57, FNTB, MRE11A, NTRK1, SSX2IP, CEP63, DUSP3, FAM160A1, MTMR4, SYCE3, RALBP1, CDC16, NCAPH2, KLHL10, KLHL20 | TGS1 | EED, CREBBP, EP300, NCOA6, MED1, HNF4A, COIL, LIN28A, SNRPA1, FBL, FAM177A1, XPO1, SEPT7, CRY1, ERCC5, MYBPH, SEPT2, SORBS1, MAGED2, AFG3L2, DNAJB4, ZZEF1, SCRIB, RSRC1, ZMYM1, LSM10, SNCA, SSX2IP, LSM11, SEPT10, SNRPN, SNRPF, SNRPE, SNRPG, SNRNP70, TGS1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for HOOK3_TGS1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for HOOK3_TGS1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | HOOK3 | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human |
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