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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 1660

FusionGeneSummary for ANAPC7_PDE11A

check button Fusion gene summary
Fusion gene informationFusion gene name: ANAPC7_PDE11A
Fusion gene ID: 1660
HgeneTgene
Gene symbol

ANAPC7

PDE11A

Gene ID

51434

50940

Gene nameanaphase promoting complex subunit 7phosphodiesterase 11A
SynonymsAPC7PPNAD2
Cytomap

12q24.11

2q31.2

Type of geneprotein-codingprotein-coding
Descriptionanaphase-promoting complex subunit 7cyclosome subunit 7dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AcAMP and cGMP cyclic nucleotide phosphodiesterase 11A
Modification date2018052220180329
UniProtAcc

Q9UJX3

Q9HCR9

Ensembl transtripts involved in fusion geneENST00000455511, ENST00000481473, 
ENST00000450008, 
ENST00000286063, 
ENST00000358450, ENST00000450799, 
ENST00000409504, ENST00000389683, 
ENST00000449286, ENST00000497003, 
Fusion gene scores* DoF score3 X 2 X 3=188 X 4 X 6=192
# samples 38
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(8/192*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANAPC7 [Title/Abstract] AND PDE11A [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneANAPC7

GO:0070979

protein K11-linked ubiquitination

18485873


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDOVTCGA-31-1951-01AANAPC7chr12

110832906

-PDE11Achr2

178592900

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000455511ENST00000286063ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
In-frameENST00000455511ENST00000358450ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
5CDS-intronENST00000455511ENST00000450799ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
5CDS-intronENST00000455511ENST00000409504ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
5CDS-intronENST00000455511ENST00000389683ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
5CDS-intronENST00000455511ENST00000449286ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
5CDS-5UTRENST00000455511ENST00000497003ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
intron-3CDSENST00000481473ENST00000286063ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
intron-3CDSENST00000481473ENST00000358450ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
intron-intronENST00000481473ENST00000450799ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
intron-intronENST00000481473ENST00000409504ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
intron-intronENST00000481473ENST00000389683ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
intron-intronENST00000481473ENST00000449286ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
intron-5UTRENST00000481473ENST00000497003ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
In-frameENST00000450008ENST00000286063ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
In-frameENST00000450008ENST00000358450ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
5CDS-intronENST00000450008ENST00000450799ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
5CDS-intronENST00000450008ENST00000409504ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
5CDS-intronENST00000450008ENST00000389683ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
5CDS-intronENST00000450008ENST00000449286ANAPC7chr12

110832906

-PDE11Achr2

178592900

-
5CDS-5UTRENST00000450008ENST00000497003ANAPC7chr12

110832906

-PDE11Achr2

178592900

-

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FusionProtFeatures for ANAPC7_PDE11A


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ANAPC7

Q9UJX3

PDE11A

Q9HCR9

Component of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated E3 ubiquitin ligase that controlsprogression through mitosis and the G1 phase of the cell cycle.The APC/C complex acts by mediating ubiquitination and subsequentdegradation of target proteins: it mainly mediates the formationof 'Lys-11'-linked polyubiquitin chains and, to a lower extent,the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitinchains. {ECO:0000269|PubMed:18485873}. Plays a role in signal transduction by regulating theintracellular concentration of cyclic nucleotides cAMP and cGMP.Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively. {ECO:0000269|PubMed:10725373,ECO:0000269|PubMed:10906126, ECO:0000269|PubMed:11050148}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANAPC7chr12:110832906chr2:178592900ENST00000450008-310135_168170538RepeatNote=TPR 1
HgeneANAPC7chr12:110832906chr2:178592900ENST00000455511-311135_168170600RepeatNote=TPR 1
TgenePDE11Achr12:110832906chr2:178592900ENST00000358450-1021402_558346684DomainNote=GAF 2
TgenePDE11Achr12:110832906chr2:178592900ENST00000358450-1021588_912346684DomainPDEase
TgenePDE11Achr12:110832906chr2:178592900ENST00000389683-617217_370152490DomainNote=GAF 1
TgenePDE11Achr12:110832906chr2:178592900ENST00000389683-617402_558152490DomainNote=GAF 2
TgenePDE11Achr12:110832906chr2:178592900ENST00000389683-617588_912152490DomainPDEase
TgenePDE11Achr12:110832906chr2:178592900ENST00000409504-820402_558238663DomainNote=GAF 2
TgenePDE11Achr12:110832906chr2:178592900ENST00000409504-820588_912238663DomainPDEase
TgenePDE11Achr12:110832906chr2:178592900ENST00000449286-819402_558238576DomainNote=GAF 2
TgenePDE11Achr12:110832906chr2:178592900ENST00000449286-819588_912238576DomainPDEase

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANAPC7chr12:110832906chr2:178592900ENST00000450008-310203_236170538RepeatNote=TPR 2
HgeneANAPC7chr12:110832906chr2:178592900ENST00000450008-310237_270170538RepeatNote=TPR 3
HgeneANAPC7chr12:110832906chr2:178592900ENST00000450008-310271_304170538RepeatNote=TPR 4
HgeneANAPC7chr12:110832906chr2:178592900ENST00000450008-310373_406170538RepeatNote=TPR 5
HgeneANAPC7chr12:110832906chr2:178592900ENST00000450008-310407_440170538RepeatNote=TPR 6
HgeneANAPC7chr12:110832906chr2:178592900ENST00000450008-310441_475170538RepeatNote=TPR 7
HgeneANAPC7chr12:110832906chr2:178592900ENST00000450008-310476_508170538RepeatNote=TPR 8
HgeneANAPC7chr12:110832906chr2:178592900ENST00000450008-310509_542170538RepeatNote=TPR 9
HgeneANAPC7chr12:110832906chr2:178592900ENST00000450008-310543_565170538RepeatNote=TPR 10
HgeneANAPC7chr12:110832906chr2:178592900ENST00000455511-311203_236170600RepeatNote=TPR 2
HgeneANAPC7chr12:110832906chr2:178592900ENST00000455511-311237_270170600RepeatNote=TPR 3
HgeneANAPC7chr12:110832906chr2:178592900ENST00000455511-311271_304170600RepeatNote=TPR 4
HgeneANAPC7chr12:110832906chr2:178592900ENST00000455511-311373_406170600RepeatNote=TPR 5
HgeneANAPC7chr12:110832906chr2:178592900ENST00000455511-311407_440170600RepeatNote=TPR 6
HgeneANAPC7chr12:110832906chr2:178592900ENST00000455511-311441_475170600RepeatNote=TPR 7
HgeneANAPC7chr12:110832906chr2:178592900ENST00000455511-311476_508170600RepeatNote=TPR 8
HgeneANAPC7chr12:110832906chr2:178592900ENST00000455511-311509_542170600RepeatNote=TPR 9
HgeneANAPC7chr12:110832906chr2:178592900ENST00000455511-311543_565170600RepeatNote=TPR 10
TgenePDE11Achr12:110832906chr2:178592900ENST00000286063-920217_370596934DomainNote=GAF 1
TgenePDE11Achr12:110832906chr2:178592900ENST00000286063-920402_558596934DomainNote=GAF 2
TgenePDE11Achr12:110832906chr2:178592900ENST00000286063-920588_912596934DomainPDEase
TgenePDE11Achr12:110832906chr2:178592900ENST00000358450-1021217_370346684DomainNote=GAF 1
TgenePDE11Achr12:110832906chr2:178592900ENST00000409504-820217_370238663DomainNote=GAF 1
TgenePDE11Achr12:110832906chr2:178592900ENST00000449286-819217_370238576DomainNote=GAF 1


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FusionGeneSequence for ANAPC7_PDE11A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ANAPC7_ENST00000455511_chr12_110832906_-_PDE11A_ENST00000286063_chr2_178592900_-_508aa
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVTHADSLFHD
KETRNAVSKTTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECTTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDTETLCRWLLTVRKNTRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLTGTSATLEHHHFNHAVMILQSEGHNIFANLSSKETSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI

>In-frame_ANAPC7_ENST00000455511_chr12_110832906_-_PDE11A_ENST00000358450_chr2_178592900_-_508aa
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVTHADSLFHD
KETRNAVSKTTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECTTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDTETLCRWLLTVRKNTRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLTGTSATLEHHHFNHAVMILQSEGHNIFANLSSKETSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI

>In-frame_ANAPC7_ENST00000450008_chr12_110832906_-_PDE11A_ENST00000286063_chr2_178592900_-_508aa
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVTHADSLFHD
KETRNAVSKTTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECTTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDTETLCRWLLTVRKNTRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLTGTSATLEHHHFNHAVMILQSEGHNIFANLSSKETSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI

>In-frame_ANAPC7_ENST00000450008_chr12_110832906_-_PDE11A_ENST00000358450_chr2_178592900_-_508aa
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVTHADSLFHD
KETRNAVSKTTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECTTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDTETLCRWLLTVRKNTRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLTGTSATLEHHHFNHAVMILQSEGHNIFANLSSKETSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ANAPC7_ENST00000455511_chr12_110832906_-_PDE11A_ENST00000286063_chr2_178592900_-_1524nt
ATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGCT
TTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTTA
CTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGAT
AAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAACT
GGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAAA
CAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACTT
GCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGATG
GTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTGG
AGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGCG
GTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACTC
TATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCTG
TCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGAA
TTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGAC
CTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAGA
TTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCATC
TGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGAA

>In-frame_ANAPC7_ENST00000455511_chr12_110832906_-_PDE11A_ENST00000358450_chr2_178592900_-_1524nt
ATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGCT
TTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTTA
CTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGAT
AAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAACT
GGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAAA
CAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACTT
GCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGATG
GTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTGG
AGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGCG
GTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACTC
TATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCTG
TCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGAA
TTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGAC
CTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAGA
TTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCATC
TGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGAA

>In-frame_ANAPC7_ENST00000450008_chr12_110832906_-_PDE11A_ENST00000286063_chr2_178592900_-_1524nt
ATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGCT
TTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTTA
CTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGAT
AAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAACT
GGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAAA
CAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACTT
GCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGATG
GTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTGG
AGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGCG
GTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACTC
TATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCTG
TCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGAA
TTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGAC
CTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAGA
TTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCATC
TGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGAA

>In-frame_ANAPC7_ENST00000450008_chr12_110832906_-_PDE11A_ENST00000358450_chr2_178592900_-_1524nt
ATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGCT
TTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTTA
CTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGAT
AAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAACT
GGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAAA
CAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACTT
GCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGATG
GTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTGG
AGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGCG
GTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACTC
TATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCTG
TCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGAA
TTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGAC
CTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAGA
TTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCATC
TGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGAA


* Fusion transcript sequences (Full-length transcript).
>In-frame_ANAPC7_ENST00000455511_chr12_110832906_-_PDE11A_ENST00000286063_chr2_178592900_-_7680nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA
ACATGTTTTAACCTTACAACTCTTTGTTCAAATAAATCTTTCAATGAATCCCCAACATATAAAACGTCAAAAAGCTGAATTCCTATGTGA
ATTATAAGCAGGGTTTGGACATCCAGAGCACCTACAAACCTTCATCTCTTTGATTACGTACATGGGGGTCCACAGGGACTCTGAAGAGTT
TGAAAATCCCTGGCCTAGATTAAACCTGAGAGCCATTCTAGCTCTTAAAAAAATCTGAAATTTACAAACCATTTTTCTTGTTATTGTTTT
TGTTTCTTTGTTTGTTTGTTTTTTGAGACTGAGTTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTTACTGCAAC
CTCTGCTTCCTGGGTTCAAGCAATTCTCCAGCCTCAACCTCCTGAGAAGCTGGGATTACAGGTGCCTGCCACCACGCCTGGCTAATTTTT
GTACTTTTAGTAGACACAGGGTTTCACCATGTTTGCCAGGCTGATCTCAAACTCCTGACCTCAGGTGAGCCACCCACCTCTGCCTCCGAA
AGTGCTGGGATTACAGGCGTGAGCCACCGTACCCGGCCCTTGTTATTGTTATTAATCATTATCAATCATTAACTTTACAGATATTAAAGA
AATAGGGGCCATGTTCTACATGCGACATTGTTTTCCTGGCACACAGTAGACAATTCAGGAAATGTCTGAAGAAGGAATGGGTAAAATTAA
GATACCAAAATGGAATTGAGGGGAGAGCAGGTAATTGTAGAGAAAAAGACTCTTTATGGCAAGAAACAAAGTAAAAGAAATGTATAGACC
GGGCGCGGTGGCTCACGCCTGTAATCCCAGCAATTTGGAAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCGTCCTGGCTA
ACACGGTGAAACCCTGTCTCTACTAAAAAACACAAAACAAATTAGCCAGGCGCGGTGGCAGGCGTCTGTAGTCCCAGCTACTGGGGAGGC
TGAGGCAAGAGAATGGCGGGAACCCGCGAGGCGGAGCTTGCAGTGAGTCGAGATCACGTCACTGCCCTCCAGCCTGGGCGACCAGCGAGA
CTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGTATAAACCAGACTAAGAGGGGAATAAAAGCAAGAAGAAAAAGAAA
CGTAAGAACACCAGTAAAGGAAAGACAGGGACCGAGACAGGTGGTTAAGGGAAATGAAAAAAAAAAAAAAAAGGTGAAAGTCAATCCAAA
CAAAGAAAAATGGCACTTCCAACCAAAAAAAATGAAGGTGTAGAACCCTGTCATCAATTGCTCAGAAAAGAGAGACACTTGAGCAGGGAG
GGGTTTGAGAAAGGGGAGAAGGAAGGAGTGAGAGCCCTAAAAAATAATGTTCCTAGCTACCCTTTACAGCTGTCTCTGCAGGGAAGACTG
GAGAAAGTAGAGGGGGAAATGAATGCAGGAAGAAACTGCCTCTGCAGAGCAGGTAAGAGGAGGTTGTTCAGATTTATGGATTTTATTAAG
CCAGTTTTCTGTATCACTCTGCTATAAAGGAAAATAGCTTCTGCAGGGCTGTCTCTCCTCCTTCAGGTGGGGAACAAAGGGTGGGTGGAG
TCAGGGACAGAGTCTGGTCTGCGAGATCGTGACGTGTCTGCAGCTCCGAAGCACTGCAGGTGTTTCTGGGTAATGTGCCACATCATGTTT
ATATCACGAACGGGAATTGAAAATCAGTCTGTGTGAGGCAGAGATGAGCCCACATCTGTTATCCTCCCCAACAATAAATAAATAAATAGC
CCAGACAAATGGATGCCAGTCCATCTACAGCAACATTTTAAAGCATGTGCTTTATGACAAAACTGGACCCAGGGTCTGACAGAGACTGCA
GGCTGCCGTGAGCACTGTAGCTATCCTGAACATTGATGCTACATATTGCTAAGGGGAACATAATTTATAGCATAAACCCTACAAGCTTCC
ACTAAGGTTGAGTTTTCCTCTCATTTTCTTGCCGTTTTATTGGCTTCACTGCATGGTTGCCAATAGCAACATCCACTGGTAGCAAGGGGA
GTTCAACACCATTGCAATCTGCCATACAGTGGAGCCCTGACAATGTCAACCATCAATCTAGTAGCTGTTTGTAATTGCCTCCATCTATTT
CTCCTGTCTTGAGGTATCTTTCCTATTGTGGGTCAAGATTTAGAAACTGCTGACTAATGCCATGGGTCTGTGTCTCCATGACTATGAAGC
AGTGGACAGGAAGGTAGCAGCTTCCTGGTGCCAACAACCCCAGAGGTTAGAGGTTGAACTCTTGCGGGTTTCAGGCGTTTTTAATCCCTT
TTCTAAACAATTTATAATTTTGCAAGAATGTGAGGCATATGCAGTTATCCATATAATCTGCTTTTCCAAAAAAGAGAAAGGAAGTTTCCC
AGTCCTTATTATTAATGTTTATTTCCTATTGGAGAAAGACATTTGAAATATGAGCCTTCTTGTAAAAACTCAAACTGACCAGATTATGTT
TGCTTCCTCAGGTCTCTTGGCATTAATTGTTGAAATAACTTCATCCTACTTTTTCGATGAGATGTATTTTTTTCAGACATATTTATTCTT
ACTAGTCACTATGTAGCTATTATGTGCACAATCTACAATGTAGTGGCAATCCTGGTGGGTAGGGACAGCTTCACATACTGCAAAGGGTGC
CATTCAGTGCATAGCAGACTGGAACTCCCTCCTAGCTTGGCCACCAGCTGAACCTGTAATCTTAGGACTCTCCAAGTCTTAGAATCTCCA
TCTATTACATAAAAGCACTGACTTTTATTCAGTCCCCACACCAAAGGACCAAGACGTGTTTAGCTTTAAAGAAATTTTCCAGATAATTTT
CTTTTTTATTCTTCTCAAATAAAATAGCAACAAACCTAAAGCAGTCATCTTCTTAATAAAGACATAATAAAACTTACATATATGGGGTAG
ATGTAAGCACAATCATACTACAGATGTATCTTGAGCCTGTCTCTAATTATGATGAAAGATGTAGTCATCAATACAATTTAAAAAAAGATA
TGTCCTTTTTTTGAGACAGGGTCTTGCTCTGTCACCCAGGCTGGAGGGCAGTGGCACAATCACAGCCACTGCAGCCTTGACCTCTCCAAC
TTAAGTGATCTTTCCTGCCTCAGCCTCATGAGTAGCTGGGACCACAGGTGTGCACCACCACACCCAGCTAAATTTTGTATTGTTTGTAAA
GACGAGGCCTCACTATGCTGACCACACTGGTCTCGAACTCCTGGGCTCAAGCAATCCTCCTGCCTTGGCCTCCCAAAGTGTTAGGGTTAG
AGATATGAACCACCACACCCACCTTATATGTCCTTTTATTTCATAAAAAACAATTTTAGATTATCTGATATCACACATATCCCATAAATG
GTAGTCATTAATTTAGAAGTGAATTTATAAAGTTAAGAGAAGTTAAAATTGCACATGCATTTTGTTTCTAAAATCTGAGATGTCTATGCA
TTTCCAGGTATTGTATATTTGCAAATACATTGGGTTAGAAATCATCTTTAACATTTTGTGTTAGTGTAATAACAATATTATCTAATATTA
ATGCTGCCAGAATCCAGTTGCTTTTTCTGTGTATCAAAATTTATCATAACTTTTTCCACTTAACACTAGGTAATTAAACAGAATCTGCCC
AATTTATTCTGCAGTAAAATTATTTTAAAATCTATTTTTCCTGCTGACTCTTAGAAATTGCAGAAAGACAAAAACCAGTTTCATCTCCAG
TAATAGTGTGAAACAATTTCCTTCCAGTGGGACAGAAACCTAGACATACTAGGGAAAGATTTAAATATAAAGAAAAATGCCTTGGCTGAA
AAAAAAAAAAACCACCAAAACACAAAAAGGATTCATTAAAGCAACAGAACAAAACCTAATTTGGGACCCTAAAAACTCTGGCAATGCCAC
TGTAATGAAGTTTCATTATCTGCTTCAGAGTAACAGTCTCTGAAATTGTTATTCTGCTACATGCTGTAAAGAACTCCCAAAACTCAAATG
TATCAGGAAATGTAAAGGTTAAGTCTGACTACAAGAAGGCCAAAATTGCACCAGCTTCCTAAGTGAAGAATAATAGAATAAAACATATAG
AGGGCAGAAATAAAATGAGGTGTATCTGGAGAATTTCATGATGAGCATTTAGATTTAGCAATGCCCAATGTCATGCTGACACTGTTTGTC
ATGACCTTGTCTTCAGCTAGTAATTTGGGGTTGTACTTTTTTAAATTTAATTTTGAATGTTCTTGCATGTTTGGTACCTCTCTCCTCACT
GCTAAAGATAAATTGTTTATCTGTATAACATAACTACACCAATGTCATTTTTGTATACGCTAGTACACAAATGTGTTTTTTTATTAAGTA
ATGAAGTATTTGCTGTGAAAAATGTATTATTTGTGCCACCGTTTATATCTGTGTTCATTTTCTGTGTGTATATGCGTGTGTATTCGAATC
TCAATTTTTCTTTTACTCTAGTTTAGATTAAGACATATTTAGATGAAATTTTAAAAATAACATTGGAAATAGGAGGCTAAGTTTTGTTGA
GTCTCATTCCCTTGGGGGGAAATTGCTTTTGCCATTTTATTTTCATGTACAATAACCTAAAAAGGATCTCCTACTGACTTCCTTCCTAAT
TATTATTGTTTTACACGAAAGAAAGGAAATACGTTTTCAATTGAGTTGTTTGAAATCATTCACTTTGTGTAGATTTCCCAGACTGATGTT
TCATTGTAAGAATATTACATTATAGACAGGTTGGCCATTTCACAAGCAACTAATCCATAGTTTTGGAAGCCCGCTTTAAGAGACCTGAAT

>In-frame_ANAPC7_ENST00000455511_chr12_110832906_-_PDE11A_ENST00000358450_chr2_178592900_-_2863nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA

>In-frame_ANAPC7_ENST00000450008_chr12_110832906_-_PDE11A_ENST00000286063_chr2_178592900_-_7680nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA
ACATGTTTTAACCTTACAACTCTTTGTTCAAATAAATCTTTCAATGAATCCCCAACATATAAAACGTCAAAAAGCTGAATTCCTATGTGA
ATTATAAGCAGGGTTTGGACATCCAGAGCACCTACAAACCTTCATCTCTTTGATTACGTACATGGGGGTCCACAGGGACTCTGAAGAGTT
TGAAAATCCCTGGCCTAGATTAAACCTGAGAGCCATTCTAGCTCTTAAAAAAATCTGAAATTTACAAACCATTTTTCTTGTTATTGTTTT
TGTTTCTTTGTTTGTTTGTTTTTTGAGACTGAGTTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTTACTGCAAC
CTCTGCTTCCTGGGTTCAAGCAATTCTCCAGCCTCAACCTCCTGAGAAGCTGGGATTACAGGTGCCTGCCACCACGCCTGGCTAATTTTT
GTACTTTTAGTAGACACAGGGTTTCACCATGTTTGCCAGGCTGATCTCAAACTCCTGACCTCAGGTGAGCCACCCACCTCTGCCTCCGAA
AGTGCTGGGATTACAGGCGTGAGCCACCGTACCCGGCCCTTGTTATTGTTATTAATCATTATCAATCATTAACTTTACAGATATTAAAGA
AATAGGGGCCATGTTCTACATGCGACATTGTTTTCCTGGCACACAGTAGACAATTCAGGAAATGTCTGAAGAAGGAATGGGTAAAATTAA
GATACCAAAATGGAATTGAGGGGAGAGCAGGTAATTGTAGAGAAAAAGACTCTTTATGGCAAGAAACAAAGTAAAAGAAATGTATAGACC
GGGCGCGGTGGCTCACGCCTGTAATCCCAGCAATTTGGAAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCGTCCTGGCTA
ACACGGTGAAACCCTGTCTCTACTAAAAAACACAAAACAAATTAGCCAGGCGCGGTGGCAGGCGTCTGTAGTCCCAGCTACTGGGGAGGC
TGAGGCAAGAGAATGGCGGGAACCCGCGAGGCGGAGCTTGCAGTGAGTCGAGATCACGTCACTGCCCTCCAGCCTGGGCGACCAGCGAGA
CTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGTATAAACCAGACTAAGAGGGGAATAAAAGCAAGAAGAAAAAGAAA
CGTAAGAACACCAGTAAAGGAAAGACAGGGACCGAGACAGGTGGTTAAGGGAAATGAAAAAAAAAAAAAAAAGGTGAAAGTCAATCCAAA
CAAAGAAAAATGGCACTTCCAACCAAAAAAAATGAAGGTGTAGAACCCTGTCATCAATTGCTCAGAAAAGAGAGACACTTGAGCAGGGAG
GGGTTTGAGAAAGGGGAGAAGGAAGGAGTGAGAGCCCTAAAAAATAATGTTCCTAGCTACCCTTTACAGCTGTCTCTGCAGGGAAGACTG
GAGAAAGTAGAGGGGGAAATGAATGCAGGAAGAAACTGCCTCTGCAGAGCAGGTAAGAGGAGGTTGTTCAGATTTATGGATTTTATTAAG
CCAGTTTTCTGTATCACTCTGCTATAAAGGAAAATAGCTTCTGCAGGGCTGTCTCTCCTCCTTCAGGTGGGGAACAAAGGGTGGGTGGAG
TCAGGGACAGAGTCTGGTCTGCGAGATCGTGACGTGTCTGCAGCTCCGAAGCACTGCAGGTGTTTCTGGGTAATGTGCCACATCATGTTT
ATATCACGAACGGGAATTGAAAATCAGTCTGTGTGAGGCAGAGATGAGCCCACATCTGTTATCCTCCCCAACAATAAATAAATAAATAGC
CCAGACAAATGGATGCCAGTCCATCTACAGCAACATTTTAAAGCATGTGCTTTATGACAAAACTGGACCCAGGGTCTGACAGAGACTGCA
GGCTGCCGTGAGCACTGTAGCTATCCTGAACATTGATGCTACATATTGCTAAGGGGAACATAATTTATAGCATAAACCCTACAAGCTTCC
ACTAAGGTTGAGTTTTCCTCTCATTTTCTTGCCGTTTTATTGGCTTCACTGCATGGTTGCCAATAGCAACATCCACTGGTAGCAAGGGGA
GTTCAACACCATTGCAATCTGCCATACAGTGGAGCCCTGACAATGTCAACCATCAATCTAGTAGCTGTTTGTAATTGCCTCCATCTATTT
CTCCTGTCTTGAGGTATCTTTCCTATTGTGGGTCAAGATTTAGAAACTGCTGACTAATGCCATGGGTCTGTGTCTCCATGACTATGAAGC
AGTGGACAGGAAGGTAGCAGCTTCCTGGTGCCAACAACCCCAGAGGTTAGAGGTTGAACTCTTGCGGGTTTCAGGCGTTTTTAATCCCTT
TTCTAAACAATTTATAATTTTGCAAGAATGTGAGGCATATGCAGTTATCCATATAATCTGCTTTTCCAAAAAAGAGAAAGGAAGTTTCCC
AGTCCTTATTATTAATGTTTATTTCCTATTGGAGAAAGACATTTGAAATATGAGCCTTCTTGTAAAAACTCAAACTGACCAGATTATGTT
TGCTTCCTCAGGTCTCTTGGCATTAATTGTTGAAATAACTTCATCCTACTTTTTCGATGAGATGTATTTTTTTCAGACATATTTATTCTT
ACTAGTCACTATGTAGCTATTATGTGCACAATCTACAATGTAGTGGCAATCCTGGTGGGTAGGGACAGCTTCACATACTGCAAAGGGTGC
CATTCAGTGCATAGCAGACTGGAACTCCCTCCTAGCTTGGCCACCAGCTGAACCTGTAATCTTAGGACTCTCCAAGTCTTAGAATCTCCA
TCTATTACATAAAAGCACTGACTTTTATTCAGTCCCCACACCAAAGGACCAAGACGTGTTTAGCTTTAAAGAAATTTTCCAGATAATTTT
CTTTTTTATTCTTCTCAAATAAAATAGCAACAAACCTAAAGCAGTCATCTTCTTAATAAAGACATAATAAAACTTACATATATGGGGTAG
ATGTAAGCACAATCATACTACAGATGTATCTTGAGCCTGTCTCTAATTATGATGAAAGATGTAGTCATCAATACAATTTAAAAAAAGATA
TGTCCTTTTTTTGAGACAGGGTCTTGCTCTGTCACCCAGGCTGGAGGGCAGTGGCACAATCACAGCCACTGCAGCCTTGACCTCTCCAAC
TTAAGTGATCTTTCCTGCCTCAGCCTCATGAGTAGCTGGGACCACAGGTGTGCACCACCACACCCAGCTAAATTTTGTATTGTTTGTAAA
GACGAGGCCTCACTATGCTGACCACACTGGTCTCGAACTCCTGGGCTCAAGCAATCCTCCTGCCTTGGCCTCCCAAAGTGTTAGGGTTAG
AGATATGAACCACCACACCCACCTTATATGTCCTTTTATTTCATAAAAAACAATTTTAGATTATCTGATATCACACATATCCCATAAATG
GTAGTCATTAATTTAGAAGTGAATTTATAAAGTTAAGAGAAGTTAAAATTGCACATGCATTTTGTTTCTAAAATCTGAGATGTCTATGCA
TTTCCAGGTATTGTATATTTGCAAATACATTGGGTTAGAAATCATCTTTAACATTTTGTGTTAGTGTAATAACAATATTATCTAATATTA
ATGCTGCCAGAATCCAGTTGCTTTTTCTGTGTATCAAAATTTATCATAACTTTTTCCACTTAACACTAGGTAATTAAACAGAATCTGCCC
AATTTATTCTGCAGTAAAATTATTTTAAAATCTATTTTTCCTGCTGACTCTTAGAAATTGCAGAAAGACAAAAACCAGTTTCATCTCCAG
TAATAGTGTGAAACAATTTCCTTCCAGTGGGACAGAAACCTAGACATACTAGGGAAAGATTTAAATATAAAGAAAAATGCCTTGGCTGAA
AAAAAAAAAAACCACCAAAACACAAAAAGGATTCATTAAAGCAACAGAACAAAACCTAATTTGGGACCCTAAAAACTCTGGCAATGCCAC
TGTAATGAAGTTTCATTATCTGCTTCAGAGTAACAGTCTCTGAAATTGTTATTCTGCTACATGCTGTAAAGAACTCCCAAAACTCAAATG
TATCAGGAAATGTAAAGGTTAAGTCTGACTACAAGAAGGCCAAAATTGCACCAGCTTCCTAAGTGAAGAATAATAGAATAAAACATATAG
AGGGCAGAAATAAAATGAGGTGTATCTGGAGAATTTCATGATGAGCATTTAGATTTAGCAATGCCCAATGTCATGCTGACACTGTTTGTC
ATGACCTTGTCTTCAGCTAGTAATTTGGGGTTGTACTTTTTTAAATTTAATTTTGAATGTTCTTGCATGTTTGGTACCTCTCTCCTCACT
GCTAAAGATAAATTGTTTATCTGTATAACATAACTACACCAATGTCATTTTTGTATACGCTAGTACACAAATGTGTTTTTTTATTAAGTA
ATGAAGTATTTGCTGTGAAAAATGTATTATTTGTGCCACCGTTTATATCTGTGTTCATTTTCTGTGTGTATATGCGTGTGTATTCGAATC
TCAATTTTTCTTTTACTCTAGTTTAGATTAAGACATATTTAGATGAAATTTTAAAAATAACATTGGAAATAGGAGGCTAAGTTTTGTTGA
GTCTCATTCCCTTGGGGGGAAATTGCTTTTGCCATTTTATTTTCATGTACAATAACCTAAAAAGGATCTCCTACTGACTTCCTTCCTAAT
TATTATTGTTTTACACGAAAGAAAGGAAATACGTTTTCAATTGAGTTGTTTGAAATCATTCACTTTGTGTAGATTTCCCAGACTGATGTT
TCATTGTAAGAATATTACATTATAGACAGGTTGGCCATTTCACAAGCAACTAATCCATAGTTTTGGAAGCCCGCTTTAAGAGACCTGAAT

>In-frame_ANAPC7_ENST00000450008_chr12_110832906_-_PDE11A_ENST00000358450_chr2_178592900_-_2863nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA


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FusionGenePPI for ANAPC7_PDE11A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ANAPC7CDC27, ANAPC1, BUB1B, CDC20, CDT1, BAP1, EP300, CREBBP, UBC, ANAPC4, CDC16, SMARCAD1, SH3KBP1, ANAPC7, MDC1, USP37, COPS5, FBXO5, ANAPC5, ANAPC2, ANAPC10, ANAPC13, PAXIP1, TP53BP1, NOTCH1, ANAPC15, TRIM33, VCP, PTEN, SOX2, PHF8, UBE2S, E2F1, CCDC8, FZR1, SIRT6, GRAP2, CACNG4, MAGIX, PRKCSH, PLEKHO2, HSPB1, ANAPC16, CDC23, CDC26, NCL, SUPT6H, TAF4, NAP1L4, XPO1, CFAP97, CRY2, FOXQ1, FOXS1, CDC5L, MAD2L1, C16orf87, LAMP1, TRIM25PDE11A


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ANAPC7_PDE11A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgenePDE11AQ9HCR9DB00820TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Asmall moleculeapproved|investigational

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RelatedDiseases for ANAPC7_PDE11A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgenePDE11AC0041696Unipolar Depression1PSYGENET
TgenePDE11AC1269683Major Depressive Disorder1PSYGENET