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Fusion gene ID: 16195 |
FusionGeneSummary for HIP1_STYXL1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HIP1_STYXL1 | Fusion gene ID: 16195 | Hgene | Tgene | Gene symbol | HIP1 | STYXL1 | Gene ID | 3092 | 51657 |
| Gene name | huntingtin interacting protein 1 | serine/threonine/tyrosine interacting like 1 | |
| Synonyms | HIP-I|ILWEQ|SHON|SHONbeta|SHONgamma | DUSP24|MK-STYX|MKSTYX | |
| Cytomap | 7q11.23 | 7q11.23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | huntingtin-interacting protein 1huntingtin-interacting protein I | serine/threonine/tyrosine-interacting-like protein 1dual specificity phosphatase 24 (putative)dual specificity phosphatase inhibitor MK-STYXdual specificity protein phosphatase 24map kinase phosphatase-like protein MK-STYX | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | O00291 | Q9Y6J8 | |
| Ensembl transtripts involved in fusion gene | ENST00000336926, ENST00000434438, ENST00000479835, | ENST00000248600, ENST00000359697, ENST00000340062, ENST00000360591, ENST00000431581, ENST00000451157, ENST00000460184, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 6 X 4 X 5=120 |
| # samples | 2 | 5 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(5/120*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: HIP1 [Title/Abstract] AND STYXL1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | HIP1 | GO:0006915 | apoptotic process | 11788820 |
| Hgene | HIP1 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 11788820 |
| Hgene | HIP1 | GO:0042981 | regulation of apoptotic process | 11788820 |
| Hgene | HIP1 | GO:0048268 | clathrin coat assembly | 11577110|11889126 |
| Hgene | HIP1 | GO:0050821 | protein stabilization | 14732715 |
| Hgene | HIP1 | GO:0097190 | apoptotic signaling pathway | 11007801 |
| Tgene | STYXL1 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity | 24709986 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-24-1558-01A | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000336926 | ENST00000248600 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| In-frame | ENST00000336926 | ENST00000359697 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| In-frame | ENST00000336926 | ENST00000340062 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| In-frame | ENST00000336926 | ENST00000360591 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| In-frame | ENST00000336926 | ENST00000431581 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| In-frame | ENST00000336926 | ENST00000451157 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| 5CDS-intron | ENST00000336926 | ENST00000460184 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| In-frame | ENST00000434438 | ENST00000248600 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| In-frame | ENST00000434438 | ENST00000359697 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| In-frame | ENST00000434438 | ENST00000340062 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| In-frame | ENST00000434438 | ENST00000360591 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| In-frame | ENST00000434438 | ENST00000431581 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| In-frame | ENST00000434438 | ENST00000451157 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| 5CDS-intron | ENST00000434438 | ENST00000460184 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| 5UTR-3CDS | ENST00000479835 | ENST00000248600 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| 5UTR-3CDS | ENST00000479835 | ENST00000359697 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| 5UTR-3CDS | ENST00000479835 | ENST00000340062 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| 5UTR-3CDS | ENST00000479835 | ENST00000360591 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| 5UTR-3CDS | ENST00000479835 | ENST00000431581 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| 5UTR-3CDS | ENST00000479835 | ENST00000451157 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
| 5UTR-intron | ENST00000479835 | ENST00000460184 | HIP1 | chr7 | 75368119 | - | STYXL1 | chr7 | 75634722 | - |
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FusionProtFeatures for HIP1_STYXL1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HIP1 | STYXL1 |
| Plays a role in clathrin-mediated endocytosis andtrafficking (PubMed:11532990, PubMed:11577110, PubMed:11889126).Involved in regulating AMPA receptor trafficking in the centralnervous system in an NMDA-dependent manner (By similarity).Regulates presynaptic nerve terminal activity (By similarity).Enhances androgen receptor (AR)-mediated transcription(PubMed:16027218). May act as a proapoptotic protein that inducescell death by acting through the intrinsic apoptosis pathway(PubMed:11007801). Binds 3-phosphoinositides (via ENTH domain)(PubMed:14732715). May act through the ENTH domain to promote cellsurvival by stabilizing receptor tyrosine kinases followingligand-induced endocytosis (PubMed:14732715). May play afunctional role in the cell filament networks (PubMed:18790740).May be required for differentiation, proliferation, and/orsurvival of somatic and germline progenitors (PubMed:11007801,PubMed:12163454). {ECO:0000250|UniProtKB:Q8VD75,ECO:0000269|PubMed:11007801, ECO:0000269|PubMed:11532990,ECO:0000269|PubMed:11577110, ECO:0000269|PubMed:11889126,ECO:0000269|PubMed:12163454, ECO:0000269|PubMed:14732715,ECO:0000269|PubMed:16027218, ECO:0000269|PubMed:18790740,ECO:0000269|PubMed:9147654}. | Catalytically inactive phosphatase (PubMed:20180778,PubMed:23163895). By binding to G3BP1, inhibits the formation ofG3BP1-induced stress granules (PubMed:20180778, PubMed:23163895).Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149' (PubMed:23163895). Inhibits PTPMT1 phosphatase activity(PubMed:24709986). By inhibiting PTPMT1, positively regulatesintrinsic apoptosis (PubMed:21262771). May play a role in theformation of neurites during neuronal development(PubMed:29250526). {ECO:0000269|PubMed:20180778,ECO:0000269|PubMed:21262771, ECO:0000269|PubMed:23163895,ECO:0000269|PubMed:24709986, ECO:0000269|PubMed:29250526}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >STYXL1 | chr7:75368119 | chr7:75634722 | ENST00000248600 | - | 4 | 9 | 160_301 | 151 | 314 | Domain | Tyrosine-protein phosphatase |
| Tgene | >STYXL1 | chr7:75368119 | chr7:75634722 | ENST00000340062 | - | 2 | 7 | 160_301 | 55 | 218 | Domain | Tyrosine-protein phosphatase |
| Tgene | >STYXL1 | chr7:75368119 | chr7:75634722 | ENST00000359697 | - | 4 | 9 | 160_301 | 151 | 314 | Domain | Tyrosine-protein phosphatase |
| Tgene | >STYXL1 | chr7:75368119 | chr7:75634722 | ENST00000431581 | - | 4 | 9 | 160_301 | 151 | 314 | Domain | Tyrosine-protein phosphatase |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >HIP1 | chr7:75368119 | chr7:75634722 | ENST00000336926 | - | 1 | 31 | 368_644 | 40 | 1038 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >HIP1 | chr7:75368119 | chr7:75634722 | ENST00000434438 | - | 1 | 29 | 368_644 | 40 | 987 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >HIP1 | chr7:75368119 | chr7:75634722 | ENST00000336926 | - | 1 | 31 | 32_160 | 40 | 1038 | Domain | ENTH |
| Hgene | >HIP1 | chr7:75368119 | chr7:75634722 | ENST00000336926 | - | 1 | 31 | 771_1012 | 40 | 1038 | Domain | I/LWEQ |
| Hgene | >HIP1 | chr7:75368119 | chr7:75634722 | ENST00000434438 | - | 1 | 29 | 32_160 | 40 | 987 | Domain | ENTH |
| Hgene | >HIP1 | chr7:75368119 | chr7:75634722 | ENST00000434438 | - | 1 | 29 | 771_1012 | 40 | 987 | Domain | I/LWEQ |
| Hgene | >HIP1 | chr7:75368119 | chr7:75634722 | ENST00000336926 | - | 1 | 31 | 410_491 | 40 | 1038 | Region | Note=pDED |
| Hgene | >HIP1 | chr7:75368119 | chr7:75634722 | ENST00000336926 | - | 1 | 31 | 867_924 | 40 | 1038 | Region | Important for actin binding |
| Hgene | >HIP1 | chr7:75368119 | chr7:75634722 | ENST00000434438 | - | 1 | 29 | 410_491 | 40 | 987 | Region | Note=pDED |
| Hgene | >HIP1 | chr7:75368119 | chr7:75634722 | ENST00000434438 | - | 1 | 29 | 867_924 | 40 | 987 | Region | Important for actin binding |
| Tgene | STYXL1 | chr7:75368119 | chr7:75634722 | ENST00000248600 | - | 4 | 9 | 27_138 | 151 | 314 | Domain | Rhodanese |
| Tgene | STYXL1 | chr7:75368119 | chr7:75634722 | ENST00000340062 | - | 2 | 7 | 27_138 | 55 | 218 | Domain | Rhodanese |
| Tgene | STYXL1 | chr7:75368119 | chr7:75634722 | ENST00000359697 | - | 4 | 9 | 27_138 | 151 | 314 | Domain | Rhodanese |
| Tgene | STYXL1 | chr7:75368119 | chr7:75634722 | ENST00000431581 | - | 4 | 9 | 27_138 | 151 | 314 | Domain | Rhodanese |
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FusionGeneSequence for HIP1_STYXL1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000248600_chr7_75634722_-_203aa MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQELDAFQPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFF AGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVS >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000359697_chr7_75634722_-_203aa MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQELDAFQPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFF AGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVS >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000340062_chr7_75634722_-_203aa MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQELDAFQPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFF AGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVS >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000360591_chr7_75634722_-_50aa >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000431581_chr7_75634722_-_203aa MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQELDAFQPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFF AGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVS >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000451157_chr7_75634722_-_172aa MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQELDAFQPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFF >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000248600_chr7_75634722_-_203aa MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQELDAFQPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFF AGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVS >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000359697_chr7_75634722_-_203aa MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQELDAFQPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFF AGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVS >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000340062_chr7_75634722_-_203aa MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQELDAFQPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFF AGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVS >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000360591_chr7_75634722_-_50aa >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000431581_chr7_75634722_-_203aa MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQELDAFQPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFF AGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVS >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000451157_chr7_75634722_-_172aa MDRMASSMKQVPNPLPKVLSRRGVGAGLEAAERESFERTQELDAFQPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFF |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000248600_chr7_75634722_-_609nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG GCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTGCCAGGGAAGGTCTTCGTTGGC AATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCCATGGATACAGGGCCCTTTTTT GCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTCTTACGCCACATGTGTCACTTC ATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGTGCCGCCATCATAGCCTACCTC ATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGTCCAAATCGGGGATTGGTGAGC >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000359697_chr7_75634722_-_609nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG GCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTGCCAGGGAAGGTCTTCGTTGGC AATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCCATGGATACAGGGCCCTTTTTT GCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTCTTACGCCACATGTGTCACTTC ATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGTGCCGCCATCATAGCCTACCTC ATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGTCCAAATCGGGGATTGGTGAGC >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000340062_chr7_75634722_-_609nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG GCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTGCCAGGGAAGGTCTTCGTTGGC AATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCCATGGATACAGGGCCCTTTTTT GCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTCTTACGCCACATGTGTCACTTC ATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGTGCCGCCATCATAGCCTACCTC ATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGTCCAAATCGGGGATTGGTGAGC >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000360591_chr7_75634722_-_152nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000431581_chr7_75634722_-_609nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG GCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTGCCAGGGAAGGTCTTCGTTGGC AATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCCATGGATACAGGGCCCTTTTTT GCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTCTTACGCCACATGTGTCACTTC ATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGTGCCGCCATCATAGCCTACCTC ATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGTCCAAATCGGGGATTGGTGAGC >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000451157_chr7_75634722_-_516nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG GCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTGCCAGGGAAGGTCTTCGTTGGC AATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCCATGGATACAGGGCCCTTTTTT GCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTCTTACGCCACATGTGTCACTTC ATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGTGCCGCCATCATAGCCTACCTC >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000248600_chr7_75634722_-_609nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG GCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTGCCAGGGAAGGTCTTCGTTGGC AATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCCATGGATACAGGGCCCTTTTTT GCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTCTTACGCCACATGTGTCACTTC ATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGTGCCGCCATCATAGCCTACCTC ATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGTCCAAATCGGGGATTGGTGAGC >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000359697_chr7_75634722_-_609nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG GCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTGCCAGGGAAGGTCTTCGTTGGC AATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCCATGGATACAGGGCCCTTTTTT GCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTCTTACGCCACATGTGTCACTTC ATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGTGCCGCCATCATAGCCTACCTC ATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGTCCAAATCGGGGATTGGTGAGC >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000340062_chr7_75634722_-_609nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG GCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTGCCAGGGAAGGTCTTCGTTGGC AATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCCATGGATACAGGGCCCTTTTTT GCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTCTTACGCCACATGTGTCACTTC ATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGTGCCGCCATCATAGCCTACCTC ATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGTCCAAATCGGGGATTGGTGAGC >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000360591_chr7_75634722_-_152nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000431581_chr7_75634722_-_609nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG GCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTGCCAGGGAAGGTCTTCGTTGGC AATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCCATGGATACAGGGCCCTTTTTT GCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTCTTACGCCACATGTGTCACTTC ATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGTGCCGCCATCATAGCCTACCTC ATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGTCCAAATCGGGGATTGGTGAGC >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000451157_chr7_75634722_-_516nt ATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGGGTCGGCGCTGGGCTGGAGGCG GCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTGCCAGGGAAGGTCTTCGTTGGC AATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCCATGGATACAGGGCCCTTTTTT GCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTCTTACGCCACATGTGTCACTTC ATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGTGCCGCCATCATAGCCTACCTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000248600_chr7_75634722_-_766nt GCCCCTGACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGG CGCGGGGTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAA ATCGTGCCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAAT GTCTCCATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTT CCCTTCTTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGC AGTTGTGCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAAC ATGTGTCCAAATCGGGGATTGGTGAGCCAGCTGCTGGAATGGGAGAAGACTATCCTTGGAGATTCCATCACAAACATCATGGATCCGCTC TACTGATCTTCTCCGAGGCCCACCGAAGGGTACTGAAGAGCCTCACCTGGGGGCATTTTGTGGGTGGAGGGCCAGAGTGTGTATACCCAG >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000359697_chr7_75634722_-_762nt GCCCCTGACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGG CGCGGGGTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAA ATCGTGCCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAAT GTCTCCATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTT CCCTTCTTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGC AGTTGTGCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAAC ATGTGTCCAAATCGGGGATTGGTGAGCCAGCTGCTGGAATGGGAGAAGACTATCCTTGGAGATTCCATCACAAACATCATGGATCCGCTC TACTGATCTTCTCCGAGGCCCACCGAAGGGTACTGAAGAGCCTCACCTGGGGGCATTTTGTGGGTGGAGGGCCAGAGTGTGTATACCCAG >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000340062_chr7_75634722_-_762nt GCCCCTGACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGG CGCGGGGTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAA ATCGTGCCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAAT GTCTCCATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTT CCCTTCTTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGC AGTTGTGCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAAC ATGTGTCCAAATCGGGGATTGGTGAGCCAGCTGCTGGAATGGGAGAAGACTATCCTTGGAGATTCCATCACAAACATCATGGATCCGCTC TACTGATCTTCTCCGAGGCCCACCGAAGGGTACTGAAGAGCCTCACCTGGGGGCATTTTGTGGGTGGAGGGCCAGAGTGTGTATACCCAG >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000360591_chr7_75634722_-_761nt GCCCCTGACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGG CGCGGGGTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAA ATCGTGCCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAAT GTCTCCATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTT CCCTTCTTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGC AGTTGTGCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAAC ATGTGTCCAAATCGGGGATTGGTGAGCCAGCTGCTGGAATGGGAGAAGACTATCCTTGGAGATTCCATCACAAACATCATGGATCCGCTC TACTGATCTTCTCCGAGGCCCACCGAAGGGTACTGAAGAGCCTCACCTGGGGGCATTTTGTGGGTGGAGGGCCAGAGTGTGTATACCCAG >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000431581_chr7_75634722_-_695nt GCCCCTGACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGG CGCGGGGTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAA ATCGTGCCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAAT GTCTCCATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTT CCCTTCTTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGC AGTTGTGCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAAC ATGTGTCCAAATCGGGGATTGGTGAGCCAGCTGCTGGAATGGGAGAAGACTATCCTTGGAGATTCCATCACAAACATCATGGATCCGCTC >In-frame_HIP1_ENST00000336926_chr7_75368119_-_STYXL1_ENST00000451157_chr7_75634722_-_1094nt GCCCCTGACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGG CGCGGGGTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAA ATCGTGCCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAAT GTCTCCATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTT CCCTTCTTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGC AGTTGTGCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTACAG TAGCACAATCTCGACTCACTGCAAGCTCTGCCTCCCGGGCTCATGCCATTCTTCTGCCTCAGCCTCCCGAGTAACTGGGACTACAGGCAT CTGCCACCACTCAATTTCTTTAATATATGTAGGCCTATTCAGATTGTCTGTTTCTTCTTGTGTGAGTTTTGGCAGTCTGTGTCTTTCAAG GAATTGATCAATCACATTTGTGGATATGAATATTCTTCTATTATCCTTTTAATGTCTGTGGGATCTGTAGCAATGTCTTCTCTTTCACTT CTGTATTAGTAATTTGTGTCTTCTGTTTAAGTTAGCCTGGCTAGCGGTGTATCGATTTTATTGATCTTTTCAAAGAACCGGCTTTTGGTT TTTTTGATTTTCTCTATTGATTTCCTGTTTTCAATTTCATTCTTTGCATGGCGTATCTAGTTTTCCTAGCACCATTTGTTGAAATGACTG TCCTTTTCCCCCATCGAATGGTCTTGGCATACTATCAAAAATTCCTTGACAGGCCCGGTGCAGTGGCTCACACCTGTAATCCCAGCAGGT >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000248600_chr7_75634722_-_760nt GACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGG GTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTG CCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCC ATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTC TTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGT GCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGT CCAAATCGGGGATTGGTGAGCCAGCTGCTGGAATGGGAGAAGACTATCCTTGGAGATTCCATCACAAACATCATGGATCCGCTCTACTGA TCTTCTCCGAGGCCCACCGAAGGGTACTGAAGAGCCTCACCTGGGGGCATTTTGTGGGTGGAGGGCCAGAGTGTGTATACCCAGGCTTGT >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000359697_chr7_75634722_-_756nt GACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGG GTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTG CCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCC ATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTC TTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGT GCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGT CCAAATCGGGGATTGGTGAGCCAGCTGCTGGAATGGGAGAAGACTATCCTTGGAGATTCCATCACAAACATCATGGATCCGCTCTACTGA TCTTCTCCGAGGCCCACCGAAGGGTACTGAAGAGCCTCACCTGGGGGCATTTTGTGGGTGGAGGGCCAGAGTGTGTATACCCAGGCTTGT >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000340062_chr7_75634722_-_756nt GACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGG GTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTG CCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCC ATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTC TTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGT GCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGT CCAAATCGGGGATTGGTGAGCCAGCTGCTGGAATGGGAGAAGACTATCCTTGGAGATTCCATCACAAACATCATGGATCCGCTCTACTGA TCTTCTCCGAGGCCCACCGAAGGGTACTGAAGAGCCTCACCTGGGGGCATTTTGTGGGTGGAGGGCCAGAGTGTGTATACCCAGGCTTGT >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000360591_chr7_75634722_-_755nt GACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGG GTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTG CCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCC ATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTC TTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGT GCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGT CCAAATCGGGGATTGGTGAGCCAGCTGCTGGAATGGGAGAAGACTATCCTTGGAGATTCCATCACAAACATCATGGATCCGCTCTACTGA TCTTCTCCGAGGCCCACCGAAGGGTACTGAAGAGCCTCACCTGGGGGCATTTTGTGGGTGGAGGGCCAGAGTGTGTATACCCAGGCTTGT >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000431581_chr7_75634722_-_689nt GACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGG GTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTG CCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCC ATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTC TTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGT GCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGAGGTCCTGGGCCTATGTCAAGAAGTGCAAAAACAACATGTGT CCAAATCGGGGATTGGTGAGCCAGCTGCTGGAATGGGAGAAGACTATCCTTGGAGATTCCATCACAAACATCATGGATCCGCTCTACTGA >In-frame_HIP1_ENST00000434438_chr7_75368119_-_STYXL1_ENST00000451157_chr7_75634722_-_1088nt GACTCGGCTCCTCGCGGCGACATGGATCGGATGGCCAGCTCCATGAAGCAGGTGCCCAACCCACTGCCCAAGGTGCTGAGCCGGCGCGGG GTCGGCGCTGGGCTGGAGGCGGCGGAGCGCGAGAGCTTCGAGCGGACTCAGGAACTGGATGCATTTCAGCCATACCCCATTGAAATCGTG CCAGGGAAGGTCTTCGTTGGCAATTTCAGTCAAGCCTGTGACCCCAAGATTCAGAAGGACTTGAAAATCAAAGCCCATGTCAATGTCTCC ATGGATACAGGGCCCTTTTTTGCAGGCGATGCTGACAAGCTTCTGCACATCCGGATAGAAGATTCCCCGGAAGCCCAGATTCTTCCCTTC TTACGCCACATGTGTCACTTCATTGAAATTCACCATCACCTTGGCTCTGTCATTCTGATCTTTTCCACCCAAGGTATCAGCCGCAGTTGT GCCGCCATCATAGCCTACCTCATGCATAGTAACGAGCAGACCTTGCAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTACAGTAGCAC AATCTCGACTCACTGCAAGCTCTGCCTCCCGGGCTCATGCCATTCTTCTGCCTCAGCCTCCCGAGTAACTGGGACTACAGGCATCTGCCA CCACTCAATTTCTTTAATATATGTAGGCCTATTCAGATTGTCTGTTTCTTCTTGTGTGAGTTTTGGCAGTCTGTGTCTTTCAAGGAATTG ATCAATCACATTTGTGGATATGAATATTCTTCTATTATCCTTTTAATGTCTGTGGGATCTGTAGCAATGTCTTCTCTTTCACTTCTGTAT TAGTAATTTGTGTCTTCTGTTTAAGTTAGCCTGGCTAGCGGTGTATCGATTTTATTGATCTTTTCAAAGAACCGGCTTTTGGTTTTTTTG ATTTTCTCTATTGATTTCCTGTTTTCAATTTCATTCTTTGCATGGCGTATCTAGTTTTCCTAGCACCATTTGTTGAAATGACTGTCCTTT TCCCCCATCGAATGGTCTTGGCATACTATCAAAAATTCCTTGACAGGCCCGGTGCAGTGGCTCACACCTGTAATCCCAGCAGGTTGGGAG |
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FusionGenePPI for HIP1_STYXL1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| HIP1 | PFDN1, RPS10, EIF6, HTT, HIP1R, CLTC, IFT57, CASP8, MAPK6, ITSN1, BFAR, FBXO25, HIP1, REL, DAZAP2, MAP3K1, CCDC67, NTRK1, TMEM17, GAK, MYH9, GTSE1, SMURF1, EGFR, CPNE2, TRIM25 | STYXL1 | AES, SMC1A, RPS29, ATXN10, EHD4, PSPH, ACTA1, MYO1B, MYO1C, SPTAN1, SPTBN1, VIM |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for HIP1_STYXL1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for HIP1_STYXL1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | HIP1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
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