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Fusion gene ID: 16159 |
FusionGeneSummary for HIAT1_PALMD |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HIAT1_PALMD | Fusion gene ID: 16159 | Hgene | Tgene | Gene symbol | HIAT1 | PALMD | Gene ID | 64645 | 54873 |
| Gene name | major facilitator superfamily domain containing 14A | palmdelphin | |
| Synonyms | HIAT1 | C1orf11|PALML | |
| Cytomap | 1p21.2 | 1p21.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | hippocampus abundant transcript 1 proteinhippocampus abundant gene transcript 1putative tetracycline transporter-like proteintetracycline transporter-like protein | palmdelphinparalemmin-like proteinparalemnin-like protein | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9NP74 | ||
| Ensembl transtripts involved in fusion gene | ENST00000370152, | ENST00000263174, ENST00000605497, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 6 X 5 X 5=150 |
| # samples | 1 | 7 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(7/150*10)=-1.09953567355091 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: HIAT1 [Title/Abstract] AND PALMD [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUSC | TCGA-77-7139-01A | HIAT1 | chr1 | 100535241 | + | PALMD | chr1 | 100127875 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000370152 | ENST00000263174 | HIAT1 | chr1 | 100535241 | + | PALMD | chr1 | 100127875 | + |
| In-frame | ENST00000370152 | ENST00000605497 | HIAT1 | chr1 | 100535241 | + | PALMD | chr1 | 100127875 | + |
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FusionProtFeatures for HIAT1_PALMD |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HIAT1 | PALMD |
| Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 5_8 | 297 | 491 | Compositional bias | Note=Poly-Lys |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 125_126 | 297 | 491 | Topological domain | Cytoplasmic |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 148_160 | 297 | 491 | Topological domain | Extracellular |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 182_188 | 297 | 491 | Topological domain | Cytoplasmic |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 1_40 | 297 | 491 | Topological domain | Extracellular |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 210_243 | 297 | 491 | Topological domain | Extracellular |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 265_284 | 297 | 491 | Topological domain | Cytoplasmic |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 62_74 | 297 | 491 | Topological domain | Cytoplasmic |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 96_103 | 297 | 491 | Topological domain | Extracellular |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 104_124 | 297 | 491 | Transmembrane | Helical%3B Name%3D3 |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 127_147 | 297 | 491 | Transmembrane | Helical%3B Name%3D4 |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 161_181 | 297 | 491 | Transmembrane | Helical%3B Name%3D5 |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 189_209 | 297 | 491 | Transmembrane | Helical%3B Name%3D6 |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 244_264 | 297 | 491 | Transmembrane | Helical%3B Name%3D7 |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 41_61 | 297 | 491 | Transmembrane | Helical%3B Name%3D1 |
| Hgene | HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 75_95 | 297 | 491 | Transmembrane | Helical%3B Name%3D2 |
| Tgene | >PALMD | chr1:100535241 | chr1:100127875 | ENST00000263174 | + | 0 | 8 | 12_106 | 15 | 552 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >PALMD | chr1:100535241 | chr1:100127875 | ENST00000263174 | + | 0 | 8 | 450_459 | 15 | 552 | Compositional bias | Note=Poly-Glu |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 306_313 | 297 | 491 | Topological domain | Extracellular |
| Hgene | >HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 335_337 | 297 | 491 | Topological domain | Cytoplasmic |
| Hgene | >HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 359_379 | 297 | 491 | Topological domain | Extracellular |
| Hgene | >HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 401_427 | 297 | 491 | Topological domain | Cytoplasmic |
| Hgene | >HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 449_490 | 297 | 491 | Topological domain | Extracellular |
| Hgene | >HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 285_305 | 297 | 491 | Transmembrane | Helical%3B Name%3D8 |
| Hgene | >HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 314_334 | 297 | 491 | Transmembrane | Helical%3B Name%3D9 |
| Hgene | >HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 338_358 | 297 | 491 | Transmembrane | Helical%3B Name%3D10 |
| Hgene | >HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 380_400 | 297 | 491 | Transmembrane | Helical%3B Name%3D11 |
| Hgene | >HIAT1 | chr1:100535241 | chr1:100127875 | ENST00000370152 | + | 8 | 12 | 428_448 | 297 | 491 | Transmembrane | Helical%3B Name%3D12 |
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FusionGeneSequence for HIAT1_PALMD |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_HIAT1_ENST00000370152_chr1_100535241_+_PALMD_ENST00000263174_chr1_100127875_+_834aa MTQGKKKKRAANRSIMLAKKIIIKDGGTPQGIGSPSVYHAVIVIFLEFFAWGLLTAPTLVVLHETFPKHTFLMNGLIQGVKGLLSFLSAP LIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAY LGRVYGDSLVVVLATAIALLDICFILVAVPESLPEKMRPASWGAPISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLY LRQIMKFSPESVAAFIAVLGILSIIAQDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQVL EQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQ NRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYH EPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGVNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLM TPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDG IIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAKPTPLPRKRSEASPHENTNHKSPHKNSISLKEQEESLGSPVHHSPFDAQTTG >In-frame_HIAT1_ENST00000370152_chr1_100535241_+_PALMD_ENST00000605497_chr1_100127875_+_834aa MTQGKKKKRAANRSIMLAKKIIIKDGGTPQGIGSPSVYHAVIVIFLEFFAWGLLTAPTLVVLHETFPKHTFLMNGLIQGVKGLLSFLSAP LIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAY LGRVYGDSLVVVLATAIALLDICFILVAVPESLPEKMRPASWGAPISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLY LRQIMKFSPESVAAFIAVLGILSIIAQDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQVL EQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQ NRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYH EPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGVNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLM TPWEESNVMQDKDAPSPKPRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDG IIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAKPTPLPRKRSEASPHENTNHKSPHKNSISLKEQEESLGSPVHHSPFDAQTTG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_HIAT1_ENST00000370152_chr1_100535241_+_PALMD_ENST00000263174_chr1_100127875_+_2502nt ATGACCCAGGGGAAGAAGAAGAAACGGGCCGCGAACCGCAGTATCATGCTGGCCAAGAAGATCATCATTAAGGACGGAGGCACGCCTCAA GGAATAGGTTCTCCTAGTGTCTATCATGCAGTTATCGTCATCTTTTTGGAGTTTTTTGCTTGGGGACTATTGACAGCACCCACCTTGGTG GTATTACATGAAACCTTTCCTAAACATACATTTCTGATGAACGGCTTAATTCAAGGAGTAAAGGGTTTGTTGTCATTCCTTAGTGCCCCG CTTATTGGTGCTCTTTCTGATGTTTGGGGCCGAAAATCCTTCTTGCTGCTAACGGTGTTTTTCACATGTGCCCCAATTCCTTTAATGAAG ATCAGCCCATGGTGGTACTTTGCTGTTATCTCTGTTTCTGGGGTTTTTGCAGTGACTTTTTCTGTGGTATTTGCATACGTAGCAGATATA ACCCAAGAGCATGAAAGAAGTATGGCTTATGGACTGGTTTCAGCAACATTTGCTGCAAGTTTAGTCACCAGTCCTGCAATTGGAGCTTAT CTTGGACGAGTATATGGGGACAGCTTGGTGGTGGTCTTAGCTACAGCAATAGCTTTGCTAGATATTTGTTTTATCCTTGTTGCTGTGCCA GAGTCGTTGCCTGAGAAAATGCGGCCAGCATCCTGGGGAGCACCCATTTCCTGGGAACAAGCTGACCCTTTTGCGTCCTTAAAAAAAGTC GGCCAAGATTCCATAGTGCTGCTGATCTGCATTACAGTGTTTCTCTCCTACCTACCGGAGGCAGGCCAATATTCCAGCTTTTTTTTATAC CTCAGACAGATAATGAAATTTTCACCAGAAAGTGTTGCAGCGTTTATAGCAGTCCTTGGCATTCTTTCCATTATTGCACAGGATAAAAGA AAAATACAGGAAGAAATCTCACAGAAGCGTCTGAAAATAGAGGAAGACAAACTAAAGCACCAGCATTTGAAGAAAAAGGCCTTGAGGGAG AAATGGCTTCTAGATGGAATCAGCAGCGGAAAAGAACAGGAAGAGATGAAGAAGCAAAATCAACAAGACCAGCACCAGATCCAGGTTCTA GAACAAAGTATCCTCAGGCTTGAGAAAGAGATCCAAGATCTTGAAAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGGCCATTTTAAAG AAACTAAAGTCAATTGAGCGGACAACAGAAGACATTATAAGATCTGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGTCAATTGAGGAC ATCTATGCTAATATCCCTGACCTTCCAAAGTCCTACATACCTTCTAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAGATGATGAACAA AATAGGAAAGCTTTATATGCCATGGAAATTAAAGTTGAAAAAGACTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAATACCTCTGCCA TCAGATGACTTTAAAGGTACAGGAATAAAAGTTTATGATGATGGGCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACAGTGCAGCATAC AATGGCACCGATGGCCTGGCACCAGTTGAAGTAGAGGAACTTCTAAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAACAGAGTATCAT GAGCCTGTATATGCCAATCCCTTTTACAGGCCTACAACCCCACAGAGAGAAACGGTGACCCCTGGACCAAACTTTCAAGAAAGGATAAAG ATTAAAACTAATGGACTGGGTATTGGTGTAAATGAATCCATACACAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAAACAACTTCAAT CACATCAGTCCCATTCCGCCAGTGCCTCATCCCCGATCAGTGATTCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAAAAAGGCTAATG ACTCCTTGGGAAGAATCGAATGTCATGCAGGACAAAGATGCACCCTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAATATTTGGGAAA TCTGAACACCAGAATTCTTCACCCACTTGTCAGGAGGACGAGGAAGATGTCAGATATAATATCGTTCATTCCCTGCCTCCAGACATAAAT GATACAGAACCGGTGACAATGATTTTCATGGGGTATCAGCAGGCAGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAGGATATGATGGG ATCATCCATGCTGAGCTGGTTGTGATTGATGATGAGGAGGAGGAGGATGAAGGAGAAGCAGAGAAACCGTCCTACCACCCCATAGCTCCC CATAGTCAGGTGTACCAGCCAGCCAAACCAACACCACTTCCTAGAAAAAGATCAGAAGCTAGTCCTCATGAAAACACAAATCATAAATCC CCCCACAAAAATTCCATATCTCTGAAAGAGCAAGAAGAAAGCTTAGGCAGCCCTGTCCACCATTCCCCATTTGATGCTCAGACAACTGGA >In-frame_HIAT1_ENST00000370152_chr1_100535241_+_PALMD_ENST00000605497_chr1_100127875_+_2502nt ATGACCCAGGGGAAGAAGAAGAAACGGGCCGCGAACCGCAGTATCATGCTGGCCAAGAAGATCATCATTAAGGACGGAGGCACGCCTCAA GGAATAGGTTCTCCTAGTGTCTATCATGCAGTTATCGTCATCTTTTTGGAGTTTTTTGCTTGGGGACTATTGACAGCACCCACCTTGGTG GTATTACATGAAACCTTTCCTAAACATACATTTCTGATGAACGGCTTAATTCAAGGAGTAAAGGGTTTGTTGTCATTCCTTAGTGCCCCG CTTATTGGTGCTCTTTCTGATGTTTGGGGCCGAAAATCCTTCTTGCTGCTAACGGTGTTTTTCACATGTGCCCCAATTCCTTTAATGAAG ATCAGCCCATGGTGGTACTTTGCTGTTATCTCTGTTTCTGGGGTTTTTGCAGTGACTTTTTCTGTGGTATTTGCATACGTAGCAGATATA ACCCAAGAGCATGAAAGAAGTATGGCTTATGGACTGGTTTCAGCAACATTTGCTGCAAGTTTAGTCACCAGTCCTGCAATTGGAGCTTAT CTTGGACGAGTATATGGGGACAGCTTGGTGGTGGTCTTAGCTACAGCAATAGCTTTGCTAGATATTTGTTTTATCCTTGTTGCTGTGCCA GAGTCGTTGCCTGAGAAAATGCGGCCAGCATCCTGGGGAGCACCCATTTCCTGGGAACAAGCTGACCCTTTTGCGTCCTTAAAAAAAGTC GGCCAAGATTCCATAGTGCTGCTGATCTGCATTACAGTGTTTCTCTCCTACCTACCGGAGGCAGGCCAATATTCCAGCTTTTTTTTATAC CTCAGACAGATAATGAAATTTTCACCAGAAAGTGTTGCAGCGTTTATAGCAGTCCTTGGCATTCTTTCCATTATTGCACAGGATAAAAGA AAAATACAGGAAGAAATCTCACAGAAGCGTCTGAAAATAGAGGAAGACAAACTAAAGCACCAGCATTTGAAGAAAAAGGCCTTGAGGGAG AAATGGCTTCTAGATGGAATCAGCAGCGGAAAAGAACAGGAAGAGATGAAGAAGCAAAATCAACAAGACCAGCACCAGATCCAGGTTCTA GAACAAAGTATCCTCAGGCTTGAGAAAGAGATCCAAGATCTTGAAAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGGCCATTTTAAAG AAACTAAAGTCAATTGAGCGGACAACAGAAGACATTATAAGATCTGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGTCAATTGAGGAC ATCTATGCTAATATCCCTGACCTTCCAAAGTCCTACATACCTTCTAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAGATGATGAACAA AATAGGAAAGCTTTATATGCCATGGAAATTAAAGTTGAAAAAGACTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAATACCTCTGCCA TCAGATGACTTTAAAGGTACAGGAATAAAAGTTTATGATGATGGGCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACAGTGCAGCATAC AATGGCACCGATGGCCTGGCACCAGTTGAAGTAGAGGAACTTCTAAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAACAGAGTATCAT GAGCCTGTATATGCCAATCCCTTTTACAGGCCTACAACCCCACAGAGAGAAACGGTGACCCCTGGACCAAACTTTCAAGAAAGGATAAAG ATTAAAACTAATGGACTGGGTATTGGTGTAAATGAATCCATACACAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAAACAACTTCAAT CACATCAGTCCCATTCCGCCAGTGCCTCATCCCCGATCAGTGATTCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAAAAAGGCTAATG ACTCCTTGGGAAGAATCGAATGTCATGCAGGACAAAGATGCACCCTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAATATTTGGGAAA TCTGAACACCAGAATTCTTCACCCACTTGTCAGGAGGACGAGGAAGATGTCAGATATAATATCGTTCATTCCCTGCCTCCAGACATAAAT GATACAGAACCGGTGACAATGATTTTCATGGGGTATCAGCAGGCAGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAGGATATGATGGG ATCATCCATGCTGAGCTGGTTGTGATTGATGATGAGGAGGAGGAGGATGAAGGAGAAGCAGAGAAACCGTCCTACCACCCCATAGCTCCC CATAGTCAGGTGTACCAGCCAGCCAAACCAACACCACTTCCTAGAAAAAGATCAGAAGCTAGTCCTCATGAAAACACAAATCATAAATCC CCCCACAAAAATTCCATATCTCTGAAAGAGCAAGAAGAAAGCTTAGGCAGCCCTGTCCACCATTCCCCATTTGATGCTCAGACAACTGGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_HIAT1_ENST00000370152_chr1_100535241_+_PALMD_ENST00000263174_chr1_100127875_+_3117nt AGGCAGGCCGGGCCCTCAAGATGGCGGCGGGCGCCCAGAGCGGCTCGGCCCGGCAGTAGTGGTGGGACGGCACTAGCTGCTGGGGCCTGC CGCCCCGGGAGTGGCTGCAGCAGCGCCAGGAATCGAGGATGGTAAAATGACCCAGGGGAAGAAGAAGAAACGGGCCGCGAACCGCAGTAT CATGCTGGCCAAGAAGATCATCATTAAGGACGGAGGCACGCCTCAAGGAATAGGTTCTCCTAGTGTCTATCATGCAGTTATCGTCATCTT TTTGGAGTTTTTTGCTTGGGGACTATTGACAGCACCCACCTTGGTGGTATTACATGAAACCTTTCCTAAACATACATTTCTGATGAACGG CTTAATTCAAGGAGTAAAGGGTTTGTTGTCATTCCTTAGTGCCCCGCTTATTGGTGCTCTTTCTGATGTTTGGGGCCGAAAATCCTTCTT GCTGCTAACGGTGTTTTTCACATGTGCCCCAATTCCTTTAATGAAGATCAGCCCATGGTGGTACTTTGCTGTTATCTCTGTTTCTGGGGT TTTTGCAGTGACTTTTTCTGTGGTATTTGCATACGTAGCAGATATAACCCAAGAGCATGAAAGAAGTATGGCTTATGGACTGGTTTCAGC AACATTTGCTGCAAGTTTAGTCACCAGTCCTGCAATTGGAGCTTATCTTGGACGAGTATATGGGGACAGCTTGGTGGTGGTCTTAGCTAC AGCAATAGCTTTGCTAGATATTTGTTTTATCCTTGTTGCTGTGCCAGAGTCGTTGCCTGAGAAAATGCGGCCAGCATCCTGGGGAGCACC CATTTCCTGGGAACAAGCTGACCCTTTTGCGTCCTTAAAAAAAGTCGGCCAAGATTCCATAGTGCTGCTGATCTGCATTACAGTGTTTCT CTCCTACCTACCGGAGGCAGGCCAATATTCCAGCTTTTTTTTATACCTCAGACAGATAATGAAATTTTCACCAGAAAGTGTTGCAGCGTT TATAGCAGTCCTTGGCATTCTTTCCATTATTGCACAGGATAAAAGAAAAATACAGGAAGAAATCTCACAGAAGCGTCTGAAAATAGAGGA AGACAAACTAAAGCACCAGCATTTGAAGAAAAAGGCCTTGAGGGAGAAATGGCTTCTAGATGGAATCAGCAGCGGAAAAGAACAGGAAGA GATGAAGAAGCAAAATCAACAAGACCAGCACCAGATCCAGGTTCTAGAACAAAGTATCCTCAGGCTTGAGAAAGAGATCCAAGATCTTGA AAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGGCCATTTTAAAGAAACTAAAGTCAATTGAGCGGACAACAGAAGACATTATAAGATC TGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGTCAATTGAGGACATCTATGCTAATATCCCTGACCTTCCAAAGTCCTACATACCTTC TAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAGATGATGAACAAAATAGGAAAGCTTTATATGCCATGGAAATTAAAGTTGAAAAAGA CTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAATACCTCTGCCATCAGATGACTTTAAAGGTACAGGAATAAAAGTTTATGATGATGG GCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACAGTGCAGCATACAATGGCACCGATGGCCTGGCACCAGTTGAAGTAGAGGAACTTCT AAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAACAGAGTATCATGAGCCTGTATATGCCAATCCCTTTTACAGGCCTACAACCCCACA GAGAGAAACGGTGACCCCTGGACCAAACTTTCAAGAAAGGATAAAGATTAAAACTAATGGACTGGGTATTGGTGTAAATGAATCCATACA CAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAAACAACTTCAATCACATCAGTCCCATTCCGCCAGTGCCTCATCCCCGATCAGTGAT TCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAAAAAGGCTAATGACTCCTTGGGAAGAATCGAATGTCATGCAGGACAAAGATGCACC CTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAATATTTGGGAAATCTGAACACCAGAATTCTTCACCCACTTGTCAGGAGGACGAGGA AGATGTCAGATATAATATCGTTCATTCCCTGCCTCCAGACATAAATGATACAGAACCGGTGACAATGATTTTCATGGGGTATCAGCAGGC AGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAGGATATGATGGGATCATCCATGCTGAGCTGGTTGTGATTGATGATGAGGAGGAGGA GGATGAAGGAGAAGCAGAGAAACCGTCCTACCACCCCATAGCTCCCCATAGTCAGGTGTACCAGCCAGCCAAACCAACACCACTTCCTAG AAAAAGATCAGAAGCTAGTCCTCATGAAAACACAAATCATAAATCCCCCCACAAAAATTCCATATCTCTGAAAGAGCAAGAAGAAAGCTT AGGCAGCCCTGTCCACCATTCCCCATTTGATGCTCAGACAACTGGAGATGGGACTGAGGATCCATCCTTAACAGCTTTAAGGATGAGAAT GGCAAAGCTGGGAAAAAAGGTGATCTAAGAGTTGTACCACCTATATAAACATCCTTTGAAGAAGAAACTAAGAAGCATTTGCAAATTTCT CTTCTGGATATTTTGTTTATTTTTTCTGAAGTCCAAAAAATTATCATTACAGTGTACCATATTAAGCCATGTGAATAAGTAGTAGTCATT ATTTGTGAAAAATTCCCAAAAAGCTGGGGAAAACAAATGTGTAACTTTTCCAGTTACTTGACACGATTCAGTGGGGGAAAACCAGCATTT TTTATTCTATTGATACCAAAGCATTTCTAATAAGAGCTTGTTAAATTTAAGAATAAAGTTATTTAAAATATTCTGAGTATAGTATATTAA CTGGCATTGTAATTTTGATGATACAAAGATTGAAAGATCATAGGAAAGCATTGCCCTTCATCACAGAAGTATTCAACTCTGACAAATAAA >In-frame_HIAT1_ENST00000370152_chr1_100535241_+_PALMD_ENST00000605497_chr1_100127875_+_2799nt AGGCAGGCCGGGCCCTCAAGATGGCGGCGGGCGCCCAGAGCGGCTCGGCCCGGCAGTAGTGGTGGGACGGCACTAGCTGCTGGGGCCTGC CGCCCCGGGAGTGGCTGCAGCAGCGCCAGGAATCGAGGATGGTAAAATGACCCAGGGGAAGAAGAAGAAACGGGCCGCGAACCGCAGTAT CATGCTGGCCAAGAAGATCATCATTAAGGACGGAGGCACGCCTCAAGGAATAGGTTCTCCTAGTGTCTATCATGCAGTTATCGTCATCTT TTTGGAGTTTTTTGCTTGGGGACTATTGACAGCACCCACCTTGGTGGTATTACATGAAACCTTTCCTAAACATACATTTCTGATGAACGG CTTAATTCAAGGAGTAAAGGGTTTGTTGTCATTCCTTAGTGCCCCGCTTATTGGTGCTCTTTCTGATGTTTGGGGCCGAAAATCCTTCTT GCTGCTAACGGTGTTTTTCACATGTGCCCCAATTCCTTTAATGAAGATCAGCCCATGGTGGTACTTTGCTGTTATCTCTGTTTCTGGGGT TTTTGCAGTGACTTTTTCTGTGGTATTTGCATACGTAGCAGATATAACCCAAGAGCATGAAAGAAGTATGGCTTATGGACTGGTTTCAGC AACATTTGCTGCAAGTTTAGTCACCAGTCCTGCAATTGGAGCTTATCTTGGACGAGTATATGGGGACAGCTTGGTGGTGGTCTTAGCTAC AGCAATAGCTTTGCTAGATATTTGTTTTATCCTTGTTGCTGTGCCAGAGTCGTTGCCTGAGAAAATGCGGCCAGCATCCTGGGGAGCACC CATTTCCTGGGAACAAGCTGACCCTTTTGCGTCCTTAAAAAAAGTCGGCCAAGATTCCATAGTGCTGCTGATCTGCATTACAGTGTTTCT CTCCTACCTACCGGAGGCAGGCCAATATTCCAGCTTTTTTTTATACCTCAGACAGATAATGAAATTTTCACCAGAAAGTGTTGCAGCGTT TATAGCAGTCCTTGGCATTCTTTCCATTATTGCACAGGATAAAAGAAAAATACAGGAAGAAATCTCACAGAAGCGTCTGAAAATAGAGGA AGACAAACTAAAGCACCAGCATTTGAAGAAAAAGGCCTTGAGGGAGAAATGGCTTCTAGATGGAATCAGCAGCGGAAAAGAACAGGAAGA GATGAAGAAGCAAAATCAACAAGACCAGCACCAGATCCAGGTTCTAGAACAAAGTATCCTCAGGCTTGAGAAAGAGATCCAAGATCTTGA AAAAGCTGAACTGCAAATCTCAACGAAGGAAGAGGCCATTTTAAAGAAACTAAAGTCAATTGAGCGGACAACAGAAGACATTATAAGATC TGTGAAAGTGGAAAGAGAAGAAAGAGCAGAAGAGTCAATTGAGGACATCTATGCTAATATCCCTGACCTTCCAAAGTCCTACATACCTTC TAGGTTAAGGAAGGAGATAAATGAAGAAAAAGAAGATGATGAACAAAATAGGAAAGCTTTATATGCCATGGAAATTAAAGTTGAAAAAGA CTTGAAGACTGGAGAAAGTACAGTTCTGTCTTCAATACCTCTGCCATCAGATGACTTTAAAGGTACAGGAATAAAAGTTTATGATGATGG GCAAAAGTCAGTGTATGCAGTAAGTTCTAATCACAGTGCAGCATACAATGGCACCGATGGCCTGGCACCAGTTGAAGTAGAGGAACTTCT AAGACAAGCCTCAGAGAGAAACTCTAAATCCCCAACAGAGTATCATGAGCCTGTATATGCCAATCCCTTTTACAGGCCTACAACCCCACA GAGAGAAACGGTGACCCCTGGACCAAACTTTCAAGAAAGGATAAAGATTAAAACTAATGGACTGGGTATTGGTGTAAATGAATCCATACA CAATATGGGCAATGGTCTTTCAGAGGAAAGGGGAAACAACTTCAATCACATCAGTCCCATTCCGCCAGTGCCTCATCCCCGATCAGTGAT TCAACAAGCAGAAGAGAAGCTTCACACCCCGCAAAAAAGGCTAATGACTCCTTGGGAAGAATCGAATGTCATGCAGGACAAAGATGCACC CTCTCCAAAGCCAAGGCTGAGCCCCAGAGAGACAATATTTGGGAAATCTGAACACCAGAATTCTTCACCCACTTGTCAGGAGGACGAGGA AGATGTCAGATATAATATCGTTCATTCCCTGCCTCCAGACATAAATGATACAGAACCGGTGACAATGATTTTCATGGGGTATCAGCAGGC AGAAGACAGTGAAGAAGATAAGAAGTTTCTGACAGGATATGATGGGATCATCCATGCTGAGCTGGTTGTGATTGATGATGAGGAGGAGGA GGATGAAGGAGAAGCAGAGAAACCGTCCTACCACCCCATAGCTCCCCATAGTCAGGTGTACCAGCCAGCCAAACCAACACCACTTCCTAG AAAAAGATCAGAAGCTAGTCCTCATGAAAACACAAATCATAAATCCCCCCACAAAAATTCCATATCTCTGAAAGAGCAAGAAGAAAGCTT AGGCAGCCCTGTCCACCATTCCCCATTTGATGCTCAGACAACTGGAGATGGGACTGAGGATCCATCCTTAACAGGTAATAAAAATGACAA GGCATGCCACTGCTGTTCAGTCATGTGACCAGCTTCTCTTGTGCTAATGCAGTCTTGCTTTCAGGCTTCTCTGACCACCTCATAAACTAA TACGCACTGAGATTTTTTTATTAATGCTGATAGAGATTATTATCACCACAGTAAAGTGATTAAGTCACTTCAAAAGATAAAGAAAGTAAA |
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FusionGenePPI for HIAT1_PALMD |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| HIAT1 | ELAVL1 | PALMD | SH3KBP1, SHMT2, NXF1, XPO1, DBN1, SORT1, TIMM13, BAG6 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for HIAT1_PALMD |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for HIAT1_PALMD |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PALMD | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
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