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Fusion gene ID: 15704 |
FusionGeneSummary for GUK1_TARBP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GUK1_TARBP1 | Fusion gene ID: 15704 | Hgene | Tgene | Gene symbol | GUK1 | TARBP1 | Gene ID | 2987 | 6894 |
| Gene name | guanylate kinase 1 | TAR (HIV-1) RNA binding protein 1 | |
| Synonyms | GMK | TRM3|TRMT3|TRP-185|TRP185 | |
| Cytomap | 1q42.13 | 1q42.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | guanylate kinaseATP:GMP phosphotransferaseGMP kinase | probable methyltransferase TARBP1TAR (HIV) RNA-binding protein 1TAR RNA loop binding proteinTAR RNA-binding protein 1TAR RNA-binding protein of 185 kDatRNA methyltransferase 3 homolog | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q16774 | Q13395 | |
| Ensembl transtripts involved in fusion gene | ENST00000366730, ENST00000391865, ENST00000366726, ENST00000312726, ENST00000366728, ENST00000366723, ENST00000366722, ENST00000366721, ENST00000366718, ENST00000470040, ENST00000366716, | ENST00000040877, ENST00000483404, | |
| Fusion gene scores | * DoF score | 11 X 12 X 2=264 | 2 X 2 X 2=8 |
| # samples | 13 | 2 | |
| ** MAII score | log2(13/264*10)=-1.02202630633 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: GUK1 [Title/Abstract] AND TARBP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | GUK1 | GO:0006163 | purine nucleotide metabolic process | 8663313 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-GM-A3XL-01A | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000366730 | ENST00000040877 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| intron-intron | ENST00000366730 | ENST00000483404 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| In-frame | ENST00000391865 | ENST00000040877 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| 5CDS-intron | ENST00000391865 | ENST00000483404 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| 5UTR-3CDS | ENST00000366726 | ENST00000040877 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| 5UTR-intron | ENST00000366726 | ENST00000483404 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| 5UTR-3CDS | ENST00000312726 | ENST00000040877 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| 5UTR-intron | ENST00000312726 | ENST00000483404 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| In-frame | ENST00000366728 | ENST00000040877 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| 5CDS-intron | ENST00000366728 | ENST00000483404 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| In-frame | ENST00000366723 | ENST00000040877 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| 5CDS-intron | ENST00000366723 | ENST00000483404 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| 5UTR-3CDS | ENST00000366722 | ENST00000040877 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| 5UTR-intron | ENST00000366722 | ENST00000483404 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| 5UTR-3CDS | ENST00000366721 | ENST00000040877 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| 5UTR-intron | ENST00000366721 | ENST00000483404 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| intron-3CDS | ENST00000366718 | ENST00000040877 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| intron-intron | ENST00000366718 | ENST00000483404 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| intron-3CDS | ENST00000470040 | ENST00000040877 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| intron-intron | ENST00000470040 | ENST00000483404 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| intron-3CDS | ENST00000366716 | ENST00000040877 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
| intron-intron | ENST00000366716 | ENST00000483404 | GUK1 | chr1 | 228328064 | + | TARBP1 | chr1 | 234603396 | - |
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FusionProtFeatures for GUK1_TARBP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GUK1 | TARBP1 |
| Essential for recycling GMP and indirectly, cGMP. | Probable S-adenosyl-L-methionine-dependentmethyltransferase which methylates RNA molecules such as tRNAs. Incase of infection by HIV-1, it binds to the loop region of TARRNA, a region also bound by RNA polymerase II. Binding of TARBP1and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive,suggesting that TARBP1 may function alone or in conjunction withHIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. Mayact by methylating HIV-1 TAR RNA. {ECO:0000269|PubMed:7638159,ECO:0000269|PubMed:8626763, ECO:0000269|PubMed:8846792}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for GUK1_TARBP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GUK1_ENST00000391865_chr1_228328064_+_TARBP1_ENST00000040877_chr1_234603396_-_1276aa MLRRPLAGLAAAALGRAPPDGCWLFHPSWHMCIYKRMFESENKILSKEGVIHFLELYETKILPFSPEFSEFIIGPLMDALSESSLYSRSP GQPIGSCSPLGLKLQKFLVTYISLLPEEIKSSFLLKFIRKMTSRHWCAVPILFLSKALANVPRHKALGIDGLLALRDVIHCTMITHQILL RGAAQCYLLQTAMNLLDVEKVSLSDVSTFLMSLRQEESLGRGTSLWTELCDWLRVNESYFKPSPTCSSIGLHKTSLNAYVKSIVQEYVKS SAWETGENCFMPDWFEAKLVSLMVLLAVDVEGMKTQYSGKQRTENVLRIFLDPLLDVLMKFSTNAYMPLLKTDRCLQLLLKLLNTCRLKG SSAQDDEVSTVLQNFFMSTTESISEFILRRLTMNELNSVSDLDRCHLYLMVLTELINLHLKVGWKRGNPIWRVISLLKNASIQHLQEMDS GQEPTVGSQIQRVVSMAALAMVCEAIDQKPELQLDSLHAGPLESFLSSLQLNQTLQKPHAEEQSSYAHPLECSSVLEESSSSQGWGKIVA QYIHDQWVCLSFLLKKYHTLIPTTGSEILEPFLPAVQMPIRTLQSALEALTVLSSDQVLPVFHCLKVLVPKLLTSSESLCIESFDMAWKI ISSLSNTQLIFWANLKAFVQFVFDNKVLTIAAKIKGQAYFKIKEIMYKIIEMSAIKTGVFNTLISYCCQSWIVSASNVSQGSLSSAKNYS ELILEACIFGTVFRRDQRLVQDVQTFIENLGHDCAANIVMENTKREDHYVRICAVKFLCLLDGSNMSHKLFIEDLAIKLLDKDELVSKSK KRYYVNSLQHRVKNRVWQTLLVLFPRLDQNFLNGIIDRIFQAGFTNNQASIKYFIEWIIILILHKFPQFLPKFWDCFSYGEENLKTSICT FLAVLSHLDIITQNIPEKKLILKQALIVVLQWCFNHNFSVRLYALVALKKLWTVCKVLSVEEFDALTPVIESSLHQVESMHGAGNAKKNW QRIQEHFFFATFHPLKDYCLETIFYILPRLSGLIEDEWITIDKFTRFTDVPLAAGFQWYLSQTQLSKLKPGDWSQQDIGTNLVEADNQAE WTDVQKKIIPWNSRVSDLDLELLFQDRAARLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWL PLVEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQYCFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIW >In-frame_GUK1_ENST00000366728_chr1_228328064_+_TARBP1_ENST00000040877_chr1_234603396_-_1276aa MLRRPLAGLAAAALGRAPPDGCWLFHPSWHMCIYKRMFESENKILSKEGVIHFLELYETKILPFSPEFSEFIIGPLMDALSESSLYSRSP GQPIGSCSPLGLKLQKFLVTYISLLPEEIKSSFLLKFIRKMTSRHWCAVPILFLSKALANVPRHKALGIDGLLALRDVIHCTMITHQILL RGAAQCYLLQTAMNLLDVEKVSLSDVSTFLMSLRQEESLGRGTSLWTELCDWLRVNESYFKPSPTCSSIGLHKTSLNAYVKSIVQEYVKS SAWETGENCFMPDWFEAKLVSLMVLLAVDVEGMKTQYSGKQRTENVLRIFLDPLLDVLMKFSTNAYMPLLKTDRCLQLLLKLLNTCRLKG SSAQDDEVSTVLQNFFMSTTESISEFILRRLTMNELNSVSDLDRCHLYLMVLTELINLHLKVGWKRGNPIWRVISLLKNASIQHLQEMDS GQEPTVGSQIQRVVSMAALAMVCEAIDQKPELQLDSLHAGPLESFLSSLQLNQTLQKPHAEEQSSYAHPLECSSVLEESSSSQGWGKIVA QYIHDQWVCLSFLLKKYHTLIPTTGSEILEPFLPAVQMPIRTLQSALEALTVLSSDQVLPVFHCLKVLVPKLLTSSESLCIESFDMAWKI ISSLSNTQLIFWANLKAFVQFVFDNKVLTIAAKIKGQAYFKIKEIMYKIIEMSAIKTGVFNTLISYCCQSWIVSASNVSQGSLSSAKNYS ELILEACIFGTVFRRDQRLVQDVQTFIENLGHDCAANIVMENTKREDHYVRICAVKFLCLLDGSNMSHKLFIEDLAIKLLDKDELVSKSK KRYYVNSLQHRVKNRVWQTLLVLFPRLDQNFLNGIIDRIFQAGFTNNQASIKYFIEWIIILILHKFPQFLPKFWDCFSYGEENLKTSICT FLAVLSHLDIITQNIPEKKLILKQALIVVLQWCFNHNFSVRLYALVALKKLWTVCKVLSVEEFDALTPVIESSLHQVESMHGAGNAKKNW QRIQEHFFFATFHPLKDYCLETIFYILPRLSGLIEDEWITIDKFTRFTDVPLAAGFQWYLSQTQLSKLKPGDWSQQDIGTNLVEADNQAE WTDVQKKIIPWNSRVSDLDLELLFQDRAARLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWL PLVEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQYCFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIW >In-frame_GUK1_ENST00000366723_chr1_228328064_+_TARBP1_ENST00000040877_chr1_234603396_-_1276aa MLRRPLAGLAAAALGRAPPDGCWLFHPSWHMCIYKRMFESENKILSKEGVIHFLELYETKILPFSPEFSEFIIGPLMDALSESSLYSRSP GQPIGSCSPLGLKLQKFLVTYISLLPEEIKSSFLLKFIRKMTSRHWCAVPILFLSKALANVPRHKALGIDGLLALRDVIHCTMITHQILL RGAAQCYLLQTAMNLLDVEKVSLSDVSTFLMSLRQEESLGRGTSLWTELCDWLRVNESYFKPSPTCSSIGLHKTSLNAYVKSIVQEYVKS SAWETGENCFMPDWFEAKLVSLMVLLAVDVEGMKTQYSGKQRTENVLRIFLDPLLDVLMKFSTNAYMPLLKTDRCLQLLLKLLNTCRLKG SSAQDDEVSTVLQNFFMSTTESISEFILRRLTMNELNSVSDLDRCHLYLMVLTELINLHLKVGWKRGNPIWRVISLLKNASIQHLQEMDS GQEPTVGSQIQRVVSMAALAMVCEAIDQKPELQLDSLHAGPLESFLSSLQLNQTLQKPHAEEQSSYAHPLECSSVLEESSSSQGWGKIVA QYIHDQWVCLSFLLKKYHTLIPTTGSEILEPFLPAVQMPIRTLQSALEALTVLSSDQVLPVFHCLKVLVPKLLTSSESLCIESFDMAWKI ISSLSNTQLIFWANLKAFVQFVFDNKVLTIAAKIKGQAYFKIKEIMYKIIEMSAIKTGVFNTLISYCCQSWIVSASNVSQGSLSSAKNYS ELILEACIFGTVFRRDQRLVQDVQTFIENLGHDCAANIVMENTKREDHYVRICAVKFLCLLDGSNMSHKLFIEDLAIKLLDKDELVSKSK KRYYVNSLQHRVKNRVWQTLLVLFPRLDQNFLNGIIDRIFQAGFTNNQASIKYFIEWIIILILHKFPQFLPKFWDCFSYGEENLKTSICT FLAVLSHLDIITQNIPEKKLILKQALIVVLQWCFNHNFSVRLYALVALKKLWTVCKVLSVEEFDALTPVIESSLHQVESMHGAGNAKKNW QRIQEHFFFATFHPLKDYCLETIFYILPRLSGLIEDEWITIDKFTRFTDVPLAAGFQWYLSQTQLSKLKPGDWSQQDIGTNLVEADNQAE WTDVQKKIIPWNSRVSDLDLELLFQDRAARLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGASVLVVGSLQCISDKQFQHLSVSAEQWL PLVEVKPPQLIDYLQQKKTEGYTIIGVEQTAKSLDLTQYCFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIW |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GUK1_ENST00000391865_chr1_228328064_+_TARBP1_ENST00000040877_chr1_234603396_-_3828nt ATGCTGCGGCGCCCGCTGGCCGGGCTGGCTGCGGCCGCCCTGGGCCGGGCCCCACCGGACGGATGTTGGCTCTTTCACCCATCCTGGCAT ATGTGTATTTATAAAAGAATGTTTGAAAGTGAAAACAAAATCCTGTCCAAAGAAGGTGTTATCCATTTTTTGGAGCTGTATGAAACAAAG ATTCTTCCATTTTCACCAGAATTTTCTGAGTTTATTATTGGACCATTAATGGATGCGCTTTCAGAGAGCTCTCTGTATAGCAGGTCCCCA GGCCAGCCAATAGGAAGCTGTTCTCCATTGGGACTGAAATTACAGAAGTTTTTAGTCACTTATATTTCTCTTCTTCCAGAAGAAATAAAG AGTAGCTTCCTATTGAAGTTTATTCGGAAGATGACAAGTAGGCATTGGTGTGCTGTTCCCATTTTGTTTCTATCTAAGGCTTTGGCAAAT GTCCCAAGACATAAGGCCCTGGGTATAGATGGGCTTCTTGCTCTCAGGGATGTTATTCATTGCACTATGATCACACATCAGATTCTCCTG AGAGGGGCAGCCCAATGCTACCTTCTTCAAACAGCTATGAATTTGCTAGATGTGGAGAAAGTGTCACTTTCTGATGTCTCAACTTTTCTC ATGTCTCTGAGACAAGAGGAATCCTTAGGACGAGGAACTTCATTGTGGACAGAGCTGTGTGACTGGCTACGTGTTAATGAAAGCTATTTT AAGCCATCCCCTACGTGTAGCTCCATTGGACTTCACAAGACATCTTTAAATGCTTATGTAAAGAGCATTGTTCAAGAGTATGTTAAGTCA TCTGCTTGGGAAACAGGAGAAAACTGCTTTATGCCTGATTGGTTTGAAGCCAAGCTTGTTTCTCTGATGGTCTTGCTGGCTGTGGATGTG GAAGGAATGAAGACTCAGTATAGCGGAAAGCAGAGAACAGAGAATGTATTGCGGATATTCTTAGACCCTCTTCTGGATGTGCTTATGAAG TTTAGTACCAATGCCTACATGCCCTTGCTGAAGACTGACAGATGCCTCCAGCTGCTGTTGAAGCTGTTGAACACATGCAGGTTGAAAGGT TCCAGTGCCCAAGATGATGAGGTGTCTACTGTTCTTCAGAACTTTTTCATGTCTACTACAGAGAGCATTTCTGAATTTATTCTCAGAAGA CTTACTATGAATGAGCTAAATAGTGTTTCAGATCTGGATCGTTGCCATTTATACCTGATGGTGTTAACTGAGCTTATAAATCTGCATTTG AAGGTTGGGTGGAAAAGGGGTAACCCTATCTGGAGAGTTATTTCTCTTTTGAAAAATGCATCCATTCAGCATCTTCAAGAGATGGACAGT GGACAGGAGCCAACAGTTGGAAGTCAGATTCAGAGAGTAGTGAGCATGGCTGCCTTGGCCATGGTGTGTGAGGCCATAGACCAGAAGCCT GAGCTGCAGCTGGACTCTCTCCATGCTGGGCCCCTGGAAAGCTTCCTTTCCTCTCTTCAGCTCAATCAGACGCTGCAGAAGCCCCACGCA GAGGAGCAGAGCAGTTATGCTCACCCCTTGGAGTGCAGCAGTGTTTTGGAAGAATCGTCATCTTCCCAAGGATGGGGAAAAATAGTTGCA CAATATATTCATGATCAATGGGTGTGCCTCTCTTTCCTGTTGAAAAAATATCACACCCTTATACCAACCACAGGGAGTGAAATTCTGGAA CCGTTTCTACCTGCCGTTCAGATGCCAATAAGGACTTTGCAGTCTGCACTAGAAGCCCTCACAGTTCTTTCTTCTGATCAAGTTTTACCA GTGTTCCATTGCTTGAAAGTGTTGGTTCCCAAGCTTCTGACTTCCTCTGAATCACTCTGCATAGAGTCTTTTGACATGGCGTGGAAAATT ATATCTTCTTTAAGCAACACTCAGCTGATATTCTGGGCTAATTTAAAAGCTTTTGTTCAGTTTGTTTTTGATAACAAAGTTCTTACCATT GCTGCCAAAATCAAGGGCCAGGCATATTTCAAAATAAAAGAGATTATGTACAAGATAATTGAAATGTCTGCTATAAAGACTGGAGTCTTC AATACACTGATAAGTTACTGCTGTCAGTCTTGGATAGTGTCTGCTTCAAATGTGTCCCAAGGATCTTTATCAAGTGCTAAAAATTATAGC GAACTTATCCTTGAGGCTTGTATATTTGGAACTGTGTTTAGGCGTGATCAAAGACTTGTTCAGGATGTACAGACCTTCATAGAAAACCTT GGACATGACTGTGCGGCAAATATTGTTATGGAAAATACTAAGAGAGAAGACCATTATGTGAGAATTTGTGCTGTCAAATTCCTGTGTTTA TTAGATGGCTCCAATATGTCCCACAAGTTGTTTATTGAGGATCTTGCAATCAAGCTATTAGATAAAGATGAATTAGTGTCCAAGTCCAAA AAACGCTACTATGTGAATTCTCTACAGCACAGAGTGAAAAACCGAGTGTGGCAGACTCTGCTGGTACTTTTCCCTAGACTTGACCAGAAT TTCTTGAATGGAATTATTGACAGGATTTTCCAGGCTGGTTTCACCAACAATCAAGCATCCATAAAATATTTTATAGAATGGATTATTATA TTGATTCTTCATAAATTCCCTCAATTTCTTCCAAAGTTCTGGGATTGTTTTTCTTATGGTGAAGAAAATCTTAAAACAAGCATTTGTACG TTTTTAGCAGTTTTATCACATTTAGACATTATTACTCAAAATATTCCAGAAAAGAAACTAATTCTGAAGCAAGCCCTTATAGTTGTGCTG CAGTGGTGTTTCAATCACAATTTTAGTGTTCGACTGTATGCTTTAGTTGCTCTTAAGAAACTCTGGACTGTGTGTAAAGTGTTAAGTGTT GAAGAATTTGATGCCCTGACTCCTGTGATTGAATCCAGCCTCCATCAAGTGGAAAGCATGCACGGAGCAGGGAATGCCAAGAAGAATTGG CAACGCATTCAGGAGCATTTCTTTTTTGCAACATTTCACCCACTCAAGGATTATTGTCTAGAGACCATATTTTACATCCTTCCACGCCTT TCAGGCCTTATTGAAGATGAATGGATCACCATTGATAAATTTACCAGATTCACTGATGTTCCTTTAGCTGCGGGATTTCAGTGGTACCTT TCTCAAACTCAACTTAGTAAACTAAAACCAGGTGACTGGTCTCAGCAAGACATAGGTACTAATTTGGTCGAAGCAGATAACCAAGCGGAG TGGACCGACGTTCAGAAGAAGATTATCCCGTGGAACAGTCGTGTTTCCGACTTAGACCTGGAGCTCCTGTTTCAGGATCGTGCTGCCAGA CTTGGAAAGTCAATTAGTAGACTCATCGTTGTGGCCTCGCTCATCGACAAACCGACCAATTTAGGAGGACTGTGCAGGACCTGTGAGGTA TTTGGGGCTTCAGTGCTCGTTGTTGGCAGCCTTCAGTGTATCAGCGACAAACAGTTTCAGCACCTCAGTGTCTCTGCAGAACAGTGGCTT CCTCTAGTGGAGGTAAAACCACCTCAGCTAATTGATTATCTGCAGCAGAAGAAAACAGAAGGTTATACCATCATTGGAGTGGAACAAACT GCCAAAAGTTTAGACCTAACCCAATATTGCTTTCCTGAGAAATCTCTGCTCTTGTTGGGAAATGAACGTGAGGGAATTCCAGCAAATCTG ATCCAACAGTTGGACGTTTGTGTGGAAATTCCTCAACAGGGCATTATCCGCTCCCTGAATGTCCATGTGAGTGGAGCCCTGCTGATCTGG >In-frame_GUK1_ENST00000366728_chr1_228328064_+_TARBP1_ENST00000040877_chr1_234603396_-_3828nt ATGCTGCGGCGCCCGCTGGCCGGGCTGGCTGCGGCCGCCCTGGGCCGGGCCCCACCGGACGGATGTTGGCTCTTTCACCCATCCTGGCAT ATGTGTATTTATAAAAGAATGTTTGAAAGTGAAAACAAAATCCTGTCCAAAGAAGGTGTTATCCATTTTTTGGAGCTGTATGAAACAAAG ATTCTTCCATTTTCACCAGAATTTTCTGAGTTTATTATTGGACCATTAATGGATGCGCTTTCAGAGAGCTCTCTGTATAGCAGGTCCCCA GGCCAGCCAATAGGAAGCTGTTCTCCATTGGGACTGAAATTACAGAAGTTTTTAGTCACTTATATTTCTCTTCTTCCAGAAGAAATAAAG AGTAGCTTCCTATTGAAGTTTATTCGGAAGATGACAAGTAGGCATTGGTGTGCTGTTCCCATTTTGTTTCTATCTAAGGCTTTGGCAAAT GTCCCAAGACATAAGGCCCTGGGTATAGATGGGCTTCTTGCTCTCAGGGATGTTATTCATTGCACTATGATCACACATCAGATTCTCCTG AGAGGGGCAGCCCAATGCTACCTTCTTCAAACAGCTATGAATTTGCTAGATGTGGAGAAAGTGTCACTTTCTGATGTCTCAACTTTTCTC ATGTCTCTGAGACAAGAGGAATCCTTAGGACGAGGAACTTCATTGTGGACAGAGCTGTGTGACTGGCTACGTGTTAATGAAAGCTATTTT AAGCCATCCCCTACGTGTAGCTCCATTGGACTTCACAAGACATCTTTAAATGCTTATGTAAAGAGCATTGTTCAAGAGTATGTTAAGTCA TCTGCTTGGGAAACAGGAGAAAACTGCTTTATGCCTGATTGGTTTGAAGCCAAGCTTGTTTCTCTGATGGTCTTGCTGGCTGTGGATGTG GAAGGAATGAAGACTCAGTATAGCGGAAAGCAGAGAACAGAGAATGTATTGCGGATATTCTTAGACCCTCTTCTGGATGTGCTTATGAAG TTTAGTACCAATGCCTACATGCCCTTGCTGAAGACTGACAGATGCCTCCAGCTGCTGTTGAAGCTGTTGAACACATGCAGGTTGAAAGGT TCCAGTGCCCAAGATGATGAGGTGTCTACTGTTCTTCAGAACTTTTTCATGTCTACTACAGAGAGCATTTCTGAATTTATTCTCAGAAGA CTTACTATGAATGAGCTAAATAGTGTTTCAGATCTGGATCGTTGCCATTTATACCTGATGGTGTTAACTGAGCTTATAAATCTGCATTTG AAGGTTGGGTGGAAAAGGGGTAACCCTATCTGGAGAGTTATTTCTCTTTTGAAAAATGCATCCATTCAGCATCTTCAAGAGATGGACAGT GGACAGGAGCCAACAGTTGGAAGTCAGATTCAGAGAGTAGTGAGCATGGCTGCCTTGGCCATGGTGTGTGAGGCCATAGACCAGAAGCCT GAGCTGCAGCTGGACTCTCTCCATGCTGGGCCCCTGGAAAGCTTCCTTTCCTCTCTTCAGCTCAATCAGACGCTGCAGAAGCCCCACGCA GAGGAGCAGAGCAGTTATGCTCACCCCTTGGAGTGCAGCAGTGTTTTGGAAGAATCGTCATCTTCCCAAGGATGGGGAAAAATAGTTGCA CAATATATTCATGATCAATGGGTGTGCCTCTCTTTCCTGTTGAAAAAATATCACACCCTTATACCAACCACAGGGAGTGAAATTCTGGAA CCGTTTCTACCTGCCGTTCAGATGCCAATAAGGACTTTGCAGTCTGCACTAGAAGCCCTCACAGTTCTTTCTTCTGATCAAGTTTTACCA GTGTTCCATTGCTTGAAAGTGTTGGTTCCCAAGCTTCTGACTTCCTCTGAATCACTCTGCATAGAGTCTTTTGACATGGCGTGGAAAATT ATATCTTCTTTAAGCAACACTCAGCTGATATTCTGGGCTAATTTAAAAGCTTTTGTTCAGTTTGTTTTTGATAACAAAGTTCTTACCATT GCTGCCAAAATCAAGGGCCAGGCATATTTCAAAATAAAAGAGATTATGTACAAGATAATTGAAATGTCTGCTATAAAGACTGGAGTCTTC AATACACTGATAAGTTACTGCTGTCAGTCTTGGATAGTGTCTGCTTCAAATGTGTCCCAAGGATCTTTATCAAGTGCTAAAAATTATAGC GAACTTATCCTTGAGGCTTGTATATTTGGAACTGTGTTTAGGCGTGATCAAAGACTTGTTCAGGATGTACAGACCTTCATAGAAAACCTT GGACATGACTGTGCGGCAAATATTGTTATGGAAAATACTAAGAGAGAAGACCATTATGTGAGAATTTGTGCTGTCAAATTCCTGTGTTTA TTAGATGGCTCCAATATGTCCCACAAGTTGTTTATTGAGGATCTTGCAATCAAGCTATTAGATAAAGATGAATTAGTGTCCAAGTCCAAA AAACGCTACTATGTGAATTCTCTACAGCACAGAGTGAAAAACCGAGTGTGGCAGACTCTGCTGGTACTTTTCCCTAGACTTGACCAGAAT TTCTTGAATGGAATTATTGACAGGATTTTCCAGGCTGGTTTCACCAACAATCAAGCATCCATAAAATATTTTATAGAATGGATTATTATA TTGATTCTTCATAAATTCCCTCAATTTCTTCCAAAGTTCTGGGATTGTTTTTCTTATGGTGAAGAAAATCTTAAAACAAGCATTTGTACG TTTTTAGCAGTTTTATCACATTTAGACATTATTACTCAAAATATTCCAGAAAAGAAACTAATTCTGAAGCAAGCCCTTATAGTTGTGCTG CAGTGGTGTTTCAATCACAATTTTAGTGTTCGACTGTATGCTTTAGTTGCTCTTAAGAAACTCTGGACTGTGTGTAAAGTGTTAAGTGTT GAAGAATTTGATGCCCTGACTCCTGTGATTGAATCCAGCCTCCATCAAGTGGAAAGCATGCACGGAGCAGGGAATGCCAAGAAGAATTGG CAACGCATTCAGGAGCATTTCTTTTTTGCAACATTTCACCCACTCAAGGATTATTGTCTAGAGACCATATTTTACATCCTTCCACGCCTT TCAGGCCTTATTGAAGATGAATGGATCACCATTGATAAATTTACCAGATTCACTGATGTTCCTTTAGCTGCGGGATTTCAGTGGTACCTT TCTCAAACTCAACTTAGTAAACTAAAACCAGGTGACTGGTCTCAGCAAGACATAGGTACTAATTTGGTCGAAGCAGATAACCAAGCGGAG TGGACCGACGTTCAGAAGAAGATTATCCCGTGGAACAGTCGTGTTTCCGACTTAGACCTGGAGCTCCTGTTTCAGGATCGTGCTGCCAGA CTTGGAAAGTCAATTAGTAGACTCATCGTTGTGGCCTCGCTCATCGACAAACCGACCAATTTAGGAGGACTGTGCAGGACCTGTGAGGTA TTTGGGGCTTCAGTGCTCGTTGTTGGCAGCCTTCAGTGTATCAGCGACAAACAGTTTCAGCACCTCAGTGTCTCTGCAGAACAGTGGCTT CCTCTAGTGGAGGTAAAACCACCTCAGCTAATTGATTATCTGCAGCAGAAGAAAACAGAAGGTTATACCATCATTGGAGTGGAACAAACT GCCAAAAGTTTAGACCTAACCCAATATTGCTTTCCTGAGAAATCTCTGCTCTTGTTGGGAAATGAACGTGAGGGAATTCCAGCAAATCTG ATCCAACAGTTGGACGTTTGTGTGGAAATTCCTCAACAGGGCATTATCCGCTCCCTGAATGTCCATGTGAGTGGAGCCCTGCTGATCTGG >In-frame_GUK1_ENST00000366723_chr1_228328064_+_TARBP1_ENST00000040877_chr1_234603396_-_3828nt ATGCTGCGGCGCCCGCTGGCCGGGCTGGCTGCGGCCGCCCTGGGCCGGGCCCCACCGGACGGATGTTGGCTCTTTCACCCATCCTGGCAT ATGTGTATTTATAAAAGAATGTTTGAAAGTGAAAACAAAATCCTGTCCAAAGAAGGTGTTATCCATTTTTTGGAGCTGTATGAAACAAAG ATTCTTCCATTTTCACCAGAATTTTCTGAGTTTATTATTGGACCATTAATGGATGCGCTTTCAGAGAGCTCTCTGTATAGCAGGTCCCCA GGCCAGCCAATAGGAAGCTGTTCTCCATTGGGACTGAAATTACAGAAGTTTTTAGTCACTTATATTTCTCTTCTTCCAGAAGAAATAAAG AGTAGCTTCCTATTGAAGTTTATTCGGAAGATGACAAGTAGGCATTGGTGTGCTGTTCCCATTTTGTTTCTATCTAAGGCTTTGGCAAAT GTCCCAAGACATAAGGCCCTGGGTATAGATGGGCTTCTTGCTCTCAGGGATGTTATTCATTGCACTATGATCACACATCAGATTCTCCTG AGAGGGGCAGCCCAATGCTACCTTCTTCAAACAGCTATGAATTTGCTAGATGTGGAGAAAGTGTCACTTTCTGATGTCTCAACTTTTCTC ATGTCTCTGAGACAAGAGGAATCCTTAGGACGAGGAACTTCATTGTGGACAGAGCTGTGTGACTGGCTACGTGTTAATGAAAGCTATTTT AAGCCATCCCCTACGTGTAGCTCCATTGGACTTCACAAGACATCTTTAAATGCTTATGTAAAGAGCATTGTTCAAGAGTATGTTAAGTCA TCTGCTTGGGAAACAGGAGAAAACTGCTTTATGCCTGATTGGTTTGAAGCCAAGCTTGTTTCTCTGATGGTCTTGCTGGCTGTGGATGTG GAAGGAATGAAGACTCAGTATAGCGGAAAGCAGAGAACAGAGAATGTATTGCGGATATTCTTAGACCCTCTTCTGGATGTGCTTATGAAG TTTAGTACCAATGCCTACATGCCCTTGCTGAAGACTGACAGATGCCTCCAGCTGCTGTTGAAGCTGTTGAACACATGCAGGTTGAAAGGT TCCAGTGCCCAAGATGATGAGGTGTCTACTGTTCTTCAGAACTTTTTCATGTCTACTACAGAGAGCATTTCTGAATTTATTCTCAGAAGA CTTACTATGAATGAGCTAAATAGTGTTTCAGATCTGGATCGTTGCCATTTATACCTGATGGTGTTAACTGAGCTTATAAATCTGCATTTG AAGGTTGGGTGGAAAAGGGGTAACCCTATCTGGAGAGTTATTTCTCTTTTGAAAAATGCATCCATTCAGCATCTTCAAGAGATGGACAGT GGACAGGAGCCAACAGTTGGAAGTCAGATTCAGAGAGTAGTGAGCATGGCTGCCTTGGCCATGGTGTGTGAGGCCATAGACCAGAAGCCT GAGCTGCAGCTGGACTCTCTCCATGCTGGGCCCCTGGAAAGCTTCCTTTCCTCTCTTCAGCTCAATCAGACGCTGCAGAAGCCCCACGCA GAGGAGCAGAGCAGTTATGCTCACCCCTTGGAGTGCAGCAGTGTTTTGGAAGAATCGTCATCTTCCCAAGGATGGGGAAAAATAGTTGCA CAATATATTCATGATCAATGGGTGTGCCTCTCTTTCCTGTTGAAAAAATATCACACCCTTATACCAACCACAGGGAGTGAAATTCTGGAA CCGTTTCTACCTGCCGTTCAGATGCCAATAAGGACTTTGCAGTCTGCACTAGAAGCCCTCACAGTTCTTTCTTCTGATCAAGTTTTACCA GTGTTCCATTGCTTGAAAGTGTTGGTTCCCAAGCTTCTGACTTCCTCTGAATCACTCTGCATAGAGTCTTTTGACATGGCGTGGAAAATT ATATCTTCTTTAAGCAACACTCAGCTGATATTCTGGGCTAATTTAAAAGCTTTTGTTCAGTTTGTTTTTGATAACAAAGTTCTTACCATT GCTGCCAAAATCAAGGGCCAGGCATATTTCAAAATAAAAGAGATTATGTACAAGATAATTGAAATGTCTGCTATAAAGACTGGAGTCTTC AATACACTGATAAGTTACTGCTGTCAGTCTTGGATAGTGTCTGCTTCAAATGTGTCCCAAGGATCTTTATCAAGTGCTAAAAATTATAGC GAACTTATCCTTGAGGCTTGTATATTTGGAACTGTGTTTAGGCGTGATCAAAGACTTGTTCAGGATGTACAGACCTTCATAGAAAACCTT GGACATGACTGTGCGGCAAATATTGTTATGGAAAATACTAAGAGAGAAGACCATTATGTGAGAATTTGTGCTGTCAAATTCCTGTGTTTA TTAGATGGCTCCAATATGTCCCACAAGTTGTTTATTGAGGATCTTGCAATCAAGCTATTAGATAAAGATGAATTAGTGTCCAAGTCCAAA AAACGCTACTATGTGAATTCTCTACAGCACAGAGTGAAAAACCGAGTGTGGCAGACTCTGCTGGTACTTTTCCCTAGACTTGACCAGAAT TTCTTGAATGGAATTATTGACAGGATTTTCCAGGCTGGTTTCACCAACAATCAAGCATCCATAAAATATTTTATAGAATGGATTATTATA TTGATTCTTCATAAATTCCCTCAATTTCTTCCAAAGTTCTGGGATTGTTTTTCTTATGGTGAAGAAAATCTTAAAACAAGCATTTGTACG TTTTTAGCAGTTTTATCACATTTAGACATTATTACTCAAAATATTCCAGAAAAGAAACTAATTCTGAAGCAAGCCCTTATAGTTGTGCTG CAGTGGTGTTTCAATCACAATTTTAGTGTTCGACTGTATGCTTTAGTTGCTCTTAAGAAACTCTGGACTGTGTGTAAAGTGTTAAGTGTT GAAGAATTTGATGCCCTGACTCCTGTGATTGAATCCAGCCTCCATCAAGTGGAAAGCATGCACGGAGCAGGGAATGCCAAGAAGAATTGG CAACGCATTCAGGAGCATTTCTTTTTTGCAACATTTCACCCACTCAAGGATTATTGTCTAGAGACCATATTTTACATCCTTCCACGCCTT TCAGGCCTTATTGAAGATGAATGGATCACCATTGATAAATTTACCAGATTCACTGATGTTCCTTTAGCTGCGGGATTTCAGTGGTACCTT TCTCAAACTCAACTTAGTAAACTAAAACCAGGTGACTGGTCTCAGCAAGACATAGGTACTAATTTGGTCGAAGCAGATAACCAAGCGGAG TGGACCGACGTTCAGAAGAAGATTATCCCGTGGAACAGTCGTGTTTCCGACTTAGACCTGGAGCTCCTGTTTCAGGATCGTGCTGCCAGA CTTGGAAAGTCAATTAGTAGACTCATCGTTGTGGCCTCGCTCATCGACAAACCGACCAATTTAGGAGGACTGTGCAGGACCTGTGAGGTA TTTGGGGCTTCAGTGCTCGTTGTTGGCAGCCTTCAGTGTATCAGCGACAAACAGTTTCAGCACCTCAGTGTCTCTGCAGAACAGTGGCTT CCTCTAGTGGAGGTAAAACCACCTCAGCTAATTGATTATCTGCAGCAGAAGAAAACAGAAGGTTATACCATCATTGGAGTGGAACAAACT GCCAAAAGTTTAGACCTAACCCAATATTGCTTTCCTGAGAAATCTCTGCTCTTGTTGGGAAATGAACGTGAGGGAATTCCAGCAAATCTG ATCCAACAGTTGGACGTTTGTGTGGAAATTCCTCAACAGGGCATTATCCGCTCCCTGAATGTCCATGTGAGTGGAGCCCTGCTGATCTGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GUK1_ENST00000391865_chr1_228328064_+_TARBP1_ENST00000040877_chr1_234603396_-_4167nt AGTCTCGCGCGCGGGCGGAGGTGGGCCGGTGCGGCGCTGTCACGTAGGTTCAGTGGGCGGAAGAGGTGGCCCCGGATGCTGCGGCGCCCG CTGGCCGGGCTGGCTGCGGCCGCCCTGGGCCGGGCCCCACCGGACGGATGTTGGCTCTTTCACCCATCCTGGCATATGTGTATTTATAAA AGAATGTTTGAAAGTGAAAACAAAATCCTGTCCAAAGAAGGTGTTATCCATTTTTTGGAGCTGTATGAAACAAAGATTCTTCCATTTTCA CCAGAATTTTCTGAGTTTATTATTGGACCATTAATGGATGCGCTTTCAGAGAGCTCTCTGTATAGCAGGTCCCCAGGCCAGCCAATAGGA AGCTGTTCTCCATTGGGACTGAAATTACAGAAGTTTTTAGTCACTTATATTTCTCTTCTTCCAGAAGAAATAAAGAGTAGCTTCCTATTG AAGTTTATTCGGAAGATGACAAGTAGGCATTGGTGTGCTGTTCCCATTTTGTTTCTATCTAAGGCTTTGGCAAATGTCCCAAGACATAAG GCCCTGGGTATAGATGGGCTTCTTGCTCTCAGGGATGTTATTCATTGCACTATGATCACACATCAGATTCTCCTGAGAGGGGCAGCCCAA TGCTACCTTCTTCAAACAGCTATGAATTTGCTAGATGTGGAGAAAGTGTCACTTTCTGATGTCTCAACTTTTCTCATGTCTCTGAGACAA GAGGAATCCTTAGGACGAGGAACTTCATTGTGGACAGAGCTGTGTGACTGGCTACGTGTTAATGAAAGCTATTTTAAGCCATCCCCTACG TGTAGCTCCATTGGACTTCACAAGACATCTTTAAATGCTTATGTAAAGAGCATTGTTCAAGAGTATGTTAAGTCATCTGCTTGGGAAACA GGAGAAAACTGCTTTATGCCTGATTGGTTTGAAGCCAAGCTTGTTTCTCTGATGGTCTTGCTGGCTGTGGATGTGGAAGGAATGAAGACT CAGTATAGCGGAAAGCAGAGAACAGAGAATGTATTGCGGATATTCTTAGACCCTCTTCTGGATGTGCTTATGAAGTTTAGTACCAATGCC TACATGCCCTTGCTGAAGACTGACAGATGCCTCCAGCTGCTGTTGAAGCTGTTGAACACATGCAGGTTGAAAGGTTCCAGTGCCCAAGAT GATGAGGTGTCTACTGTTCTTCAGAACTTTTTCATGTCTACTACAGAGAGCATTTCTGAATTTATTCTCAGAAGACTTACTATGAATGAG CTAAATAGTGTTTCAGATCTGGATCGTTGCCATTTATACCTGATGGTGTTAACTGAGCTTATAAATCTGCATTTGAAGGTTGGGTGGAAA AGGGGTAACCCTATCTGGAGAGTTATTTCTCTTTTGAAAAATGCATCCATTCAGCATCTTCAAGAGATGGACAGTGGACAGGAGCCAACA GTTGGAAGTCAGATTCAGAGAGTAGTGAGCATGGCTGCCTTGGCCATGGTGTGTGAGGCCATAGACCAGAAGCCTGAGCTGCAGCTGGAC TCTCTCCATGCTGGGCCCCTGGAAAGCTTCCTTTCCTCTCTTCAGCTCAATCAGACGCTGCAGAAGCCCCACGCAGAGGAGCAGAGCAGT TATGCTCACCCCTTGGAGTGCAGCAGTGTTTTGGAAGAATCGTCATCTTCCCAAGGATGGGGAAAAATAGTTGCACAATATATTCATGAT CAATGGGTGTGCCTCTCTTTCCTGTTGAAAAAATATCACACCCTTATACCAACCACAGGGAGTGAAATTCTGGAACCGTTTCTACCTGCC GTTCAGATGCCAATAAGGACTTTGCAGTCTGCACTAGAAGCCCTCACAGTTCTTTCTTCTGATCAAGTTTTACCAGTGTTCCATTGCTTG AAAGTGTTGGTTCCCAAGCTTCTGACTTCCTCTGAATCACTCTGCATAGAGTCTTTTGACATGGCGTGGAAAATTATATCTTCTTTAAGC AACACTCAGCTGATATTCTGGGCTAATTTAAAAGCTTTTGTTCAGTTTGTTTTTGATAACAAAGTTCTTACCATTGCTGCCAAAATCAAG GGCCAGGCATATTTCAAAATAAAAGAGATTATGTACAAGATAATTGAAATGTCTGCTATAAAGACTGGAGTCTTCAATACACTGATAAGT TACTGCTGTCAGTCTTGGATAGTGTCTGCTTCAAATGTGTCCCAAGGATCTTTATCAAGTGCTAAAAATTATAGCGAACTTATCCTTGAG GCTTGTATATTTGGAACTGTGTTTAGGCGTGATCAAAGACTTGTTCAGGATGTACAGACCTTCATAGAAAACCTTGGACATGACTGTGCG GCAAATATTGTTATGGAAAATACTAAGAGAGAAGACCATTATGTGAGAATTTGTGCTGTCAAATTCCTGTGTTTATTAGATGGCTCCAAT ATGTCCCACAAGTTGTTTATTGAGGATCTTGCAATCAAGCTATTAGATAAAGATGAATTAGTGTCCAAGTCCAAAAAACGCTACTATGTG AATTCTCTACAGCACAGAGTGAAAAACCGAGTGTGGCAGACTCTGCTGGTACTTTTCCCTAGACTTGACCAGAATTTCTTGAATGGAATT ATTGACAGGATTTTCCAGGCTGGTTTCACCAACAATCAAGCATCCATAAAATATTTTATAGAATGGATTATTATATTGATTCTTCATAAA TTCCCTCAATTTCTTCCAAAGTTCTGGGATTGTTTTTCTTATGGTGAAGAAAATCTTAAAACAAGCATTTGTACGTTTTTAGCAGTTTTA TCACATTTAGACATTATTACTCAAAATATTCCAGAAAAGAAACTAATTCTGAAGCAAGCCCTTATAGTTGTGCTGCAGTGGTGTTTCAAT CACAATTTTAGTGTTCGACTGTATGCTTTAGTTGCTCTTAAGAAACTCTGGACTGTGTGTAAAGTGTTAAGTGTTGAAGAATTTGATGCC CTGACTCCTGTGATTGAATCCAGCCTCCATCAAGTGGAAAGCATGCACGGAGCAGGGAATGCCAAGAAGAATTGGCAACGCATTCAGGAG CATTTCTTTTTTGCAACATTTCACCCACTCAAGGATTATTGTCTAGAGACCATATTTTACATCCTTCCACGCCTTTCAGGCCTTATTGAA GATGAATGGATCACCATTGATAAATTTACCAGATTCACTGATGTTCCTTTAGCTGCGGGATTTCAGTGGTACCTTTCTCAAACTCAACTT AGTAAACTAAAACCAGGTGACTGGTCTCAGCAAGACATAGGTACTAATTTGGTCGAAGCAGATAACCAAGCGGAGTGGACCGACGTTCAG AAGAAGATTATCCCGTGGAACAGTCGTGTTTCCGACTTAGACCTGGAGCTCCTGTTTCAGGATCGTGCTGCCAGACTTGGAAAGTCAATT AGTAGACTCATCGTTGTGGCCTCGCTCATCGACAAACCGACCAATTTAGGAGGACTGTGCAGGACCTGTGAGGTATTTGGGGCTTCAGTG CTCGTTGTTGGCAGCCTTCAGTGTATCAGCGACAAACAGTTTCAGCACCTCAGTGTCTCTGCAGAACAGTGGCTTCCTCTAGTGGAGGTA AAACCACCTCAGCTAATTGATTATCTGCAGCAGAAGAAAACAGAAGGTTATACCATCATTGGAGTGGAACAAACTGCCAAAAGTTTAGAC CTAACCCAATATTGCTTTCCTGAGAAATCTCTGCTCTTGTTGGGAAATGAACGTGAGGGAATTCCAGCAAATCTGATCCAACAGTTGGAC GTTTGTGTGGAAATTCCTCAACAGGGCATTATCCGCTCCCTGAATGTCCATGTGAGTGGAGCCCTGCTGATCTGGGAGTACACCAGGCAG CAGCTGCTCTCGCACGGAGATACCAAGCCATGATGTGCCTTCCTTAGTGAACTGCTGCTGCTGTTCAGACTTTTTTAAAAAAAACTATTT GGACTAAAGAAACAGATTCTGAAATTTATTGTGATAATTTGTATTTCTTTTTTCTTGCAATTTAATGCCAAAAGTTTGCCATGTGCCTTA AACATATTACTATATATTTTCCCCTTTAATAAACACTTTTTGTTAAATTGTATTCTTCCTTTAATAAAATATTTTAAGCAATTGTGGAAA >In-frame_GUK1_ENST00000366728_chr1_228328064_+_TARBP1_ENST00000040877_chr1_234603396_-_4105nt GAGGTGGCCCCGGATGCTGCGGCGCCCGCTGGCCGGGCTGGCTGCGGCCGCCCTGGGCCGGGCCCCACCGGACGGATGTTGGCTCTTTCA CCCATCCTGGCATATGTGTATTTATAAAAGAATGTTTGAAAGTGAAAACAAAATCCTGTCCAAAGAAGGTGTTATCCATTTTTTGGAGCT GTATGAAACAAAGATTCTTCCATTTTCACCAGAATTTTCTGAGTTTATTATTGGACCATTAATGGATGCGCTTTCAGAGAGCTCTCTGTA TAGCAGGTCCCCAGGCCAGCCAATAGGAAGCTGTTCTCCATTGGGACTGAAATTACAGAAGTTTTTAGTCACTTATATTTCTCTTCTTCC AGAAGAAATAAAGAGTAGCTTCCTATTGAAGTTTATTCGGAAGATGACAAGTAGGCATTGGTGTGCTGTTCCCATTTTGTTTCTATCTAA GGCTTTGGCAAATGTCCCAAGACATAAGGCCCTGGGTATAGATGGGCTTCTTGCTCTCAGGGATGTTATTCATTGCACTATGATCACACA TCAGATTCTCCTGAGAGGGGCAGCCCAATGCTACCTTCTTCAAACAGCTATGAATTTGCTAGATGTGGAGAAAGTGTCACTTTCTGATGT CTCAACTTTTCTCATGTCTCTGAGACAAGAGGAATCCTTAGGACGAGGAACTTCATTGTGGACAGAGCTGTGTGACTGGCTACGTGTTAA TGAAAGCTATTTTAAGCCATCCCCTACGTGTAGCTCCATTGGACTTCACAAGACATCTTTAAATGCTTATGTAAAGAGCATTGTTCAAGA GTATGTTAAGTCATCTGCTTGGGAAACAGGAGAAAACTGCTTTATGCCTGATTGGTTTGAAGCCAAGCTTGTTTCTCTGATGGTCTTGCT GGCTGTGGATGTGGAAGGAATGAAGACTCAGTATAGCGGAAAGCAGAGAACAGAGAATGTATTGCGGATATTCTTAGACCCTCTTCTGGA TGTGCTTATGAAGTTTAGTACCAATGCCTACATGCCCTTGCTGAAGACTGACAGATGCCTCCAGCTGCTGTTGAAGCTGTTGAACACATG CAGGTTGAAAGGTTCCAGTGCCCAAGATGATGAGGTGTCTACTGTTCTTCAGAACTTTTTCATGTCTACTACAGAGAGCATTTCTGAATT TATTCTCAGAAGACTTACTATGAATGAGCTAAATAGTGTTTCAGATCTGGATCGTTGCCATTTATACCTGATGGTGTTAACTGAGCTTAT AAATCTGCATTTGAAGGTTGGGTGGAAAAGGGGTAACCCTATCTGGAGAGTTATTTCTCTTTTGAAAAATGCATCCATTCAGCATCTTCA AGAGATGGACAGTGGACAGGAGCCAACAGTTGGAAGTCAGATTCAGAGAGTAGTGAGCATGGCTGCCTTGGCCATGGTGTGTGAGGCCAT AGACCAGAAGCCTGAGCTGCAGCTGGACTCTCTCCATGCTGGGCCCCTGGAAAGCTTCCTTTCCTCTCTTCAGCTCAATCAGACGCTGCA GAAGCCCCACGCAGAGGAGCAGAGCAGTTATGCTCACCCCTTGGAGTGCAGCAGTGTTTTGGAAGAATCGTCATCTTCCCAAGGATGGGG AAAAATAGTTGCACAATATATTCATGATCAATGGGTGTGCCTCTCTTTCCTGTTGAAAAAATATCACACCCTTATACCAACCACAGGGAG TGAAATTCTGGAACCGTTTCTACCTGCCGTTCAGATGCCAATAAGGACTTTGCAGTCTGCACTAGAAGCCCTCACAGTTCTTTCTTCTGA TCAAGTTTTACCAGTGTTCCATTGCTTGAAAGTGTTGGTTCCCAAGCTTCTGACTTCCTCTGAATCACTCTGCATAGAGTCTTTTGACAT GGCGTGGAAAATTATATCTTCTTTAAGCAACACTCAGCTGATATTCTGGGCTAATTTAAAAGCTTTTGTTCAGTTTGTTTTTGATAACAA AGTTCTTACCATTGCTGCCAAAATCAAGGGCCAGGCATATTTCAAAATAAAAGAGATTATGTACAAGATAATTGAAATGTCTGCTATAAA GACTGGAGTCTTCAATACACTGATAAGTTACTGCTGTCAGTCTTGGATAGTGTCTGCTTCAAATGTGTCCCAAGGATCTTTATCAAGTGC TAAAAATTATAGCGAACTTATCCTTGAGGCTTGTATATTTGGAACTGTGTTTAGGCGTGATCAAAGACTTGTTCAGGATGTACAGACCTT CATAGAAAACCTTGGACATGACTGTGCGGCAAATATTGTTATGGAAAATACTAAGAGAGAAGACCATTATGTGAGAATTTGTGCTGTCAA ATTCCTGTGTTTATTAGATGGCTCCAATATGTCCCACAAGTTGTTTATTGAGGATCTTGCAATCAAGCTATTAGATAAAGATGAATTAGT GTCCAAGTCCAAAAAACGCTACTATGTGAATTCTCTACAGCACAGAGTGAAAAACCGAGTGTGGCAGACTCTGCTGGTACTTTTCCCTAG ACTTGACCAGAATTTCTTGAATGGAATTATTGACAGGATTTTCCAGGCTGGTTTCACCAACAATCAAGCATCCATAAAATATTTTATAGA ATGGATTATTATATTGATTCTTCATAAATTCCCTCAATTTCTTCCAAAGTTCTGGGATTGTTTTTCTTATGGTGAAGAAAATCTTAAAAC AAGCATTTGTACGTTTTTAGCAGTTTTATCACATTTAGACATTATTACTCAAAATATTCCAGAAAAGAAACTAATTCTGAAGCAAGCCCT TATAGTTGTGCTGCAGTGGTGTTTCAATCACAATTTTAGTGTTCGACTGTATGCTTTAGTTGCTCTTAAGAAACTCTGGACTGTGTGTAA AGTGTTAAGTGTTGAAGAATTTGATGCCCTGACTCCTGTGATTGAATCCAGCCTCCATCAAGTGGAAAGCATGCACGGAGCAGGGAATGC CAAGAAGAATTGGCAACGCATTCAGGAGCATTTCTTTTTTGCAACATTTCACCCACTCAAGGATTATTGTCTAGAGACCATATTTTACAT CCTTCCACGCCTTTCAGGCCTTATTGAAGATGAATGGATCACCATTGATAAATTTACCAGATTCACTGATGTTCCTTTAGCTGCGGGATT TCAGTGGTACCTTTCTCAAACTCAACTTAGTAAACTAAAACCAGGTGACTGGTCTCAGCAAGACATAGGTACTAATTTGGTCGAAGCAGA TAACCAAGCGGAGTGGACCGACGTTCAGAAGAAGATTATCCCGTGGAACAGTCGTGTTTCCGACTTAGACCTGGAGCTCCTGTTTCAGGA TCGTGCTGCCAGACTTGGAAAGTCAATTAGTAGACTCATCGTTGTGGCCTCGCTCATCGACAAACCGACCAATTTAGGAGGACTGTGCAG GACCTGTGAGGTATTTGGGGCTTCAGTGCTCGTTGTTGGCAGCCTTCAGTGTATCAGCGACAAACAGTTTCAGCACCTCAGTGTCTCTGC AGAACAGTGGCTTCCTCTAGTGGAGGTAAAACCACCTCAGCTAATTGATTATCTGCAGCAGAAGAAAACAGAAGGTTATACCATCATTGG AGTGGAACAAACTGCCAAAAGTTTAGACCTAACCCAATATTGCTTTCCTGAGAAATCTCTGCTCTTGTTGGGAAATGAACGTGAGGGAAT TCCAGCAAATCTGATCCAACAGTTGGACGTTTGTGTGGAAATTCCTCAACAGGGCATTATCCGCTCCCTGAATGTCCATGTGAGTGGAGC CCTGCTGATCTGGGAGTACACCAGGCAGCAGCTGCTCTCGCACGGAGATACCAAGCCATGATGTGCCTTCCTTAGTGAACTGCTGCTGCT GTTCAGACTTTTTTAAAAAAAACTATTTGGACTAAAGAAACAGATTCTGAAATTTATTGTGATAATTTGTATTTCTTTTTTCTTGCAATT TAATGCCAAAAGTTTGCCATGTGCCTTAAACATATTACTATATATTTTCCCCTTTAATAAACACTTTTTGTTAAATTGTATTCTTCCTTT >In-frame_GUK1_ENST00000366723_chr1_228328064_+_TARBP1_ENST00000040877_chr1_234603396_-_4093nt GATGCTGCGGCGCCCGCTGGCCGGGCTGGCTGCGGCCGCCCTGGGCCGGGCCCCACCGGACGGATGTTGGCTCTTTCACCCATCCTGGCA TATGTGTATTTATAAAAGAATGTTTGAAAGTGAAAACAAAATCCTGTCCAAAGAAGGTGTTATCCATTTTTTGGAGCTGTATGAAACAAA GATTCTTCCATTTTCACCAGAATTTTCTGAGTTTATTATTGGACCATTAATGGATGCGCTTTCAGAGAGCTCTCTGTATAGCAGGTCCCC AGGCCAGCCAATAGGAAGCTGTTCTCCATTGGGACTGAAATTACAGAAGTTTTTAGTCACTTATATTTCTCTTCTTCCAGAAGAAATAAA GAGTAGCTTCCTATTGAAGTTTATTCGGAAGATGACAAGTAGGCATTGGTGTGCTGTTCCCATTTTGTTTCTATCTAAGGCTTTGGCAAA TGTCCCAAGACATAAGGCCCTGGGTATAGATGGGCTTCTTGCTCTCAGGGATGTTATTCATTGCACTATGATCACACATCAGATTCTCCT GAGAGGGGCAGCCCAATGCTACCTTCTTCAAACAGCTATGAATTTGCTAGATGTGGAGAAAGTGTCACTTTCTGATGTCTCAACTTTTCT CATGTCTCTGAGACAAGAGGAATCCTTAGGACGAGGAACTTCATTGTGGACAGAGCTGTGTGACTGGCTACGTGTTAATGAAAGCTATTT TAAGCCATCCCCTACGTGTAGCTCCATTGGACTTCACAAGACATCTTTAAATGCTTATGTAAAGAGCATTGTTCAAGAGTATGTTAAGTC ATCTGCTTGGGAAACAGGAGAAAACTGCTTTATGCCTGATTGGTTTGAAGCCAAGCTTGTTTCTCTGATGGTCTTGCTGGCTGTGGATGT GGAAGGAATGAAGACTCAGTATAGCGGAAAGCAGAGAACAGAGAATGTATTGCGGATATTCTTAGACCCTCTTCTGGATGTGCTTATGAA GTTTAGTACCAATGCCTACATGCCCTTGCTGAAGACTGACAGATGCCTCCAGCTGCTGTTGAAGCTGTTGAACACATGCAGGTTGAAAGG TTCCAGTGCCCAAGATGATGAGGTGTCTACTGTTCTTCAGAACTTTTTCATGTCTACTACAGAGAGCATTTCTGAATTTATTCTCAGAAG ACTTACTATGAATGAGCTAAATAGTGTTTCAGATCTGGATCGTTGCCATTTATACCTGATGGTGTTAACTGAGCTTATAAATCTGCATTT GAAGGTTGGGTGGAAAAGGGGTAACCCTATCTGGAGAGTTATTTCTCTTTTGAAAAATGCATCCATTCAGCATCTTCAAGAGATGGACAG TGGACAGGAGCCAACAGTTGGAAGTCAGATTCAGAGAGTAGTGAGCATGGCTGCCTTGGCCATGGTGTGTGAGGCCATAGACCAGAAGCC TGAGCTGCAGCTGGACTCTCTCCATGCTGGGCCCCTGGAAAGCTTCCTTTCCTCTCTTCAGCTCAATCAGACGCTGCAGAAGCCCCACGC AGAGGAGCAGAGCAGTTATGCTCACCCCTTGGAGTGCAGCAGTGTTTTGGAAGAATCGTCATCTTCCCAAGGATGGGGAAAAATAGTTGC ACAATATATTCATGATCAATGGGTGTGCCTCTCTTTCCTGTTGAAAAAATATCACACCCTTATACCAACCACAGGGAGTGAAATTCTGGA ACCGTTTCTACCTGCCGTTCAGATGCCAATAAGGACTTTGCAGTCTGCACTAGAAGCCCTCACAGTTCTTTCTTCTGATCAAGTTTTACC AGTGTTCCATTGCTTGAAAGTGTTGGTTCCCAAGCTTCTGACTTCCTCTGAATCACTCTGCATAGAGTCTTTTGACATGGCGTGGAAAAT TATATCTTCTTTAAGCAACACTCAGCTGATATTCTGGGCTAATTTAAAAGCTTTTGTTCAGTTTGTTTTTGATAACAAAGTTCTTACCAT TGCTGCCAAAATCAAGGGCCAGGCATATTTCAAAATAAAAGAGATTATGTACAAGATAATTGAAATGTCTGCTATAAAGACTGGAGTCTT CAATACACTGATAAGTTACTGCTGTCAGTCTTGGATAGTGTCTGCTTCAAATGTGTCCCAAGGATCTTTATCAAGTGCTAAAAATTATAG CGAACTTATCCTTGAGGCTTGTATATTTGGAACTGTGTTTAGGCGTGATCAAAGACTTGTTCAGGATGTACAGACCTTCATAGAAAACCT TGGACATGACTGTGCGGCAAATATTGTTATGGAAAATACTAAGAGAGAAGACCATTATGTGAGAATTTGTGCTGTCAAATTCCTGTGTTT ATTAGATGGCTCCAATATGTCCCACAAGTTGTTTATTGAGGATCTTGCAATCAAGCTATTAGATAAAGATGAATTAGTGTCCAAGTCCAA AAAACGCTACTATGTGAATTCTCTACAGCACAGAGTGAAAAACCGAGTGTGGCAGACTCTGCTGGTACTTTTCCCTAGACTTGACCAGAA TTTCTTGAATGGAATTATTGACAGGATTTTCCAGGCTGGTTTCACCAACAATCAAGCATCCATAAAATATTTTATAGAATGGATTATTAT ATTGATTCTTCATAAATTCCCTCAATTTCTTCCAAAGTTCTGGGATTGTTTTTCTTATGGTGAAGAAAATCTTAAAACAAGCATTTGTAC GTTTTTAGCAGTTTTATCACATTTAGACATTATTACTCAAAATATTCCAGAAAAGAAACTAATTCTGAAGCAAGCCCTTATAGTTGTGCT GCAGTGGTGTTTCAATCACAATTTTAGTGTTCGACTGTATGCTTTAGTTGCTCTTAAGAAACTCTGGACTGTGTGTAAAGTGTTAAGTGT TGAAGAATTTGATGCCCTGACTCCTGTGATTGAATCCAGCCTCCATCAAGTGGAAAGCATGCACGGAGCAGGGAATGCCAAGAAGAATTG GCAACGCATTCAGGAGCATTTCTTTTTTGCAACATTTCACCCACTCAAGGATTATTGTCTAGAGACCATATTTTACATCCTTCCACGCCT TTCAGGCCTTATTGAAGATGAATGGATCACCATTGATAAATTTACCAGATTCACTGATGTTCCTTTAGCTGCGGGATTTCAGTGGTACCT TTCTCAAACTCAACTTAGTAAACTAAAACCAGGTGACTGGTCTCAGCAAGACATAGGTACTAATTTGGTCGAAGCAGATAACCAAGCGGA GTGGACCGACGTTCAGAAGAAGATTATCCCGTGGAACAGTCGTGTTTCCGACTTAGACCTGGAGCTCCTGTTTCAGGATCGTGCTGCCAG ACTTGGAAAGTCAATTAGTAGACTCATCGTTGTGGCCTCGCTCATCGACAAACCGACCAATTTAGGAGGACTGTGCAGGACCTGTGAGGT ATTTGGGGCTTCAGTGCTCGTTGTTGGCAGCCTTCAGTGTATCAGCGACAAACAGTTTCAGCACCTCAGTGTCTCTGCAGAACAGTGGCT TCCTCTAGTGGAGGTAAAACCACCTCAGCTAATTGATTATCTGCAGCAGAAGAAAACAGAAGGTTATACCATCATTGGAGTGGAACAAAC TGCCAAAAGTTTAGACCTAACCCAATATTGCTTTCCTGAGAAATCTCTGCTCTTGTTGGGAAATGAACGTGAGGGAATTCCAGCAAATCT GATCCAACAGTTGGACGTTTGTGTGGAAATTCCTCAACAGGGCATTATCCGCTCCCTGAATGTCCATGTGAGTGGAGCCCTGCTGATCTG GGAGTACACCAGGCAGCAGCTGCTCTCGCACGGAGATACCAAGCCATGATGTGCCTTCCTTAGTGAACTGCTGCTGCTGTTCAGACTTTT TTAAAAAAAACTATTTGGACTAAAGAAACAGATTCTGAAATTTATTGTGATAATTTGTATTTCTTTTTTCTTGCAATTTAATGCCAAAAG TTTGCCATGTGCCTTAAACATATTACTATATATTTTCCCCTTTAATAAACACTTTTTGTTAAATTGTATTCTTCCTTTAATAAAATATTT |
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FusionGenePPI for GUK1_TARBP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GUK1 | IQCB1, HNRNPD, MOV10, NXF1, DPY19L2, TTC19, TMEM97, NDUFA4, NLGN3 | TARBP1 | WDR48, SREK1, HSF4, BSG, LYPD3, RP2, SCN2B, FAF2, ASNA1, FASN, TARS, SASS6, HNRNPD, SYNCRIP, CHMP4B, BAG6, SCN3B, TNFRSF17, DLK2, RAB6B, SCGB2A2, NEFH, GMNN, RASL10B, C19orf45, PLA2G10, FAM19A3, VSIG1, SLC2A12, RGS20, CD79B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GUK1_TARBP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GUK1_TARBP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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