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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionGeneSequence

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Fusion gene ID: 15367

FusionGeneSummary for GRB2_SS18L1

check button Fusion gene summary
Fusion gene informationFusion gene name: GRB2_SS18L1
Fusion gene ID: 15367
HgeneTgene
Gene symbol

GRB2

SS18L1

Gene ID

2885

26039

Gene namegrowth factor receptor bound protein 2SS18L1, nBAF chromatin remodeling complex subunit
SynonymsASH|EGFRBP-GRB2|Grb3-3|MST084|MSTP084|NCKAP2CREST|LP2261
Cytomap

17q25.1

20q13.33

Type of geneprotein-codingprotein-coding
Descriptiongrowth factor receptor-bound protein 2HT027SH2/SH3 adapter GRB2abundant SRC homologyepidermal growth factor receptor-binding protein GRB2growth factor receptor-bound protein 3protein Ashcalcium-responsive transactivatorSS18-like protein 1SYT homolog 1synovial sarcoma translocation gene on chromosome 18-like 1
Modification date2018052720180523
UniProtAcc

P62993

O75177

Ensembl transtripts involved in fusion geneENST00000392562, ENST00000316804, 
ENST00000316615, ENST00000392563, 
ENST00000392564, ENST00000578961, 
ENST00000462266, 
ENST00000421564, 
ENST00000331758, ENST00000370848, 
ENST00000491916, 
Fusion gene scores* DoF score11 X 4 X 9=3961 X 1 X 1=1
# samples 111
** MAII scorelog2(11/396*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(1/1*10)=3.32192809488736
Context

PubMed: GRB2 [Title/Abstract] AND SS18L1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDLUADTCGA-38-4630-01AGRB2chr17

73389632

-SS18L1chr20

60747738

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000392562ENST00000421564GRB2chr17

73389632

-SS18L1chr20

60747738

+
In-frameENST00000392562ENST00000331758GRB2chr17

73389632

-SS18L1chr20

60747738

+
In-frameENST00000392562ENST00000370848GRB2chr17

73389632

-SS18L1chr20

60747738

+
5CDS-intronENST00000392562ENST00000491916GRB2chr17

73389632

-SS18L1chr20

60747738

+
In-frameENST00000316804ENST00000421564GRB2chr17

73389632

-SS18L1chr20

60747738

+
In-frameENST00000316804ENST00000331758GRB2chr17

73389632

-SS18L1chr20

60747738

+
In-frameENST00000316804ENST00000370848GRB2chr17

73389632

-SS18L1chr20

60747738

+
5CDS-intronENST00000316804ENST00000491916GRB2chr17

73389632

-SS18L1chr20

60747738

+
In-frameENST00000316615ENST00000421564GRB2chr17

73389632

-SS18L1chr20

60747738

+
In-frameENST00000316615ENST00000331758GRB2chr17

73389632

-SS18L1chr20

60747738

+
In-frameENST00000316615ENST00000370848GRB2chr17

73389632

-SS18L1chr20

60747738

+
5CDS-intronENST00000316615ENST00000491916GRB2chr17

73389632

-SS18L1chr20

60747738

+
Frame-shitENST00000392563ENST00000421564GRB2chr17

73389632

-SS18L1chr20

60747738

+
Frame-shitENST00000392563ENST00000331758GRB2chr17

73389632

-SS18L1chr20

60747738

+
Frame-shitENST00000392563ENST00000370848GRB2chr17

73389632

-SS18L1chr20

60747738

+
5CDS-intronENST00000392563ENST00000491916GRB2chr17

73389632

-SS18L1chr20

60747738

+
Frame-shitENST00000392564ENST00000421564GRB2chr17

73389632

-SS18L1chr20

60747738

+
Frame-shitENST00000392564ENST00000331758GRB2chr17

73389632

-SS18L1chr20

60747738

+
Frame-shitENST00000392564ENST00000370848GRB2chr17

73389632

-SS18L1chr20

60747738

+
5CDS-intronENST00000392564ENST00000491916GRB2chr17

73389632

-SS18L1chr20

60747738

+
Frame-shitENST00000578961ENST00000421564GRB2chr17

73389632

-SS18L1chr20

60747738

+
Frame-shitENST00000578961ENST00000331758GRB2chr17

73389632

-SS18L1chr20

60747738

+
Frame-shitENST00000578961ENST00000370848GRB2chr17

73389632

-SS18L1chr20

60747738

+
5CDS-intronENST00000578961ENST00000491916GRB2chr17

73389632

-SS18L1chr20

60747738

+
intron-3CDSENST00000462266ENST00000421564GRB2chr17

73389632

-SS18L1chr20

60747738

+
intron-3CDSENST00000462266ENST00000331758GRB2chr17

73389632

-SS18L1chr20

60747738

+
intron-3CDSENST00000462266ENST00000370848GRB2chr17

73389632

-SS18L1chr20

60747738

+
intron-intronENST00000462266ENST00000491916GRB2chr17

73389632

-SS18L1chr20

60747738

+

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FusionProtFeatures for GRB2_SS18L1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GRB2

P62993

SS18L1

O75177

Adapter protein that provides a critical link betweencell surface growth factor receptors and the Ras signalingpathway. Isoform 2 does not bind to phosphorylated epidermalgrowth factor receptor (EGFR) but inhibits EGF-inducedtransactivation of a RAS-responsive element. Isoform 2 acts as adominant negative protein over GRB2 and by suppressingproliferative signals, may trigger active programmed cell death.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSS18L1chr17:73389632chr20:60747738ENST00000331758+711353_356305397MotifSH2-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000331758+711371_379305397MotifSH3-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000331758+711391_394305397MotifSH2-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000370848+611353_3563081118MotifSH2-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000370848+611371_3793081118MotifSH3-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000370848+611391_3943081118MotifSH2-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000421564+712353_3563051125MotifSH2-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000421564+712371_3793051125MotifSH3-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000421564+712391_3943051125MotifSH2-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000331758+711334_396305397RegionNecessary for nuclear localization
TgeneSS18L1chr17:73389632chr20:60747738ENST00000370848+611334_3963081118RegionNecessary for nuclear localization
TgeneSS18L1chr17:73389632chr20:60747738ENST00000421564+712334_3963051125RegionNecessary for nuclear localization

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGRB2chr17:73389632chr20:60747738ENST00000316615-25156_21526177DomainSH3 2
HgeneGRB2chr17:73389632chr20:60747738ENST00000316615-251_5826177DomainSH3 1
HgeneGRB2chr17:73389632chr20:60747738ENST00000316615-2560_15226177DomainSH2
HgeneGRB2chr17:73389632chr20:60747738ENST00000316804-26156_21526218DomainSH3 2
HgeneGRB2chr17:73389632chr20:60747738ENST00000316804-261_5826218DomainSH3 1
HgeneGRB2chr17:73389632chr20:60747738ENST00000316804-2660_15226218DomainSH2
HgeneGRB2chr17:73389632chr20:60747738ENST00000392562-26156_21526218DomainSH3 2
HgeneGRB2chr17:73389632chr20:60747738ENST00000392562-261_5826218DomainSH3 1
HgeneGRB2chr17:73389632chr20:60747738ENST00000392562-2660_15226218DomainSH2
HgeneGRB2chr17:73389632chr20:60747738ENST00000392563-14156_21526177DomainSH3 2
HgeneGRB2chr17:73389632chr20:60747738ENST00000392563-141_5826177DomainSH3 1
HgeneGRB2chr17:73389632chr20:60747738ENST00000392563-1460_15226177DomainSH2
HgeneGRB2chr17:73389632chr20:60747738ENST00000392564-15156_21526218DomainSH3 2
HgeneGRB2chr17:73389632chr20:60747738ENST00000392564-151_5826218DomainSH3 1
HgeneGRB2chr17:73389632chr20:60747738ENST00000392564-1560_15226218DomainSH2
TgeneSS18L1chr17:73389632chr20:60747738ENST00000331758+711190_396305397Compositional biasNote=Gln-rich
TgeneSS18L1chr17:73389632chr20:60747738ENST00000370848+611190_3963081118Compositional biasNote=Gln-rich
TgeneSS18L1chr17:73389632chr20:60747738ENST00000421564+712190_3963051125Compositional biasNote=Gln-rich
TgeneSS18L1chr17:73389632chr20:60747738ENST00000331758+71150_53305397MotifSH2-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000370848+61150_533081118MotifSH2-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000421564+71250_533051125MotifSH2-binding
TgeneSS18L1chr17:73389632chr20:60747738ENST00000331758+711149_232305397RegionMethionine-rich intra-molecular domain
TgeneSS18L1chr17:73389632chr20:60747738ENST00000331758+711246_317305397RegionMFD domain
TgeneSS18L1chr17:73389632chr20:60747738ENST00000370848+611149_2323081118RegionMethionine-rich intra-molecular domain
TgeneSS18L1chr17:73389632chr20:60747738ENST00000370848+611246_3173081118RegionMFD domain
TgeneSS18L1chr17:73389632chr20:60747738ENST00000421564+712149_2323051125RegionMethionine-rich intra-molecular domain
TgeneSS18L1chr17:73389632chr20:60747738ENST00000421564+712246_3173051125RegionMFD domain


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FusionGeneSequence for GRB2_SS18L1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_GRB2_ENST00000392562_chr17_73389632_-_SS18L1_ENST00000421564_chr20_60747738_+_117aa
MEAIAKTDFKATADDELSFKRGDILKETPSTASSRPGTSRVPRSSRRTPSSSTPASRATPGSSRATGLPREPRHSTPATSKAKASSTEAT

>In-frame_GRB2_ENST00000392562_chr17_73389632_-_SS18L1_ENST00000331758_chr20_60747738_+_117aa
MEAIAKTDFKATADDELSFKRGDILKETPSTASSRPGTSRVPRSSRRTPSSSTPASRATPGSSRATGLPREPRHSTPATSKAKASSTEAT

>In-frame_GRB2_ENST00000392562_chr17_73389632_-_SS18L1_ENST00000370848_chr20_60747738_+_117aa
MEAIAKTDFKATADDELSFKRGDILKETPSTASSRPGTSRVPRSSRRTPSSSTPASRATPGSSRATGLPREPRHSTPATSKAKASSTEAT

>In-frame_GRB2_ENST00000316804_chr17_73389632_-_SS18L1_ENST00000421564_chr20_60747738_+_117aa
MEAIAKTDFKATADDELSFKRGDILKETPSTASSRPGTSRVPRSSRRTPSSSTPASRATPGSSRATGLPREPRHSTPATSKAKASSTEAT

>In-frame_GRB2_ENST00000316804_chr17_73389632_-_SS18L1_ENST00000331758_chr20_60747738_+_117aa
MEAIAKTDFKATADDELSFKRGDILKETPSTASSRPGTSRVPRSSRRTPSSSTPASRATPGSSRATGLPREPRHSTPATSKAKASSTEAT

>In-frame_GRB2_ENST00000316804_chr17_73389632_-_SS18L1_ENST00000370848_chr20_60747738_+_117aa
MEAIAKTDFKATADDELSFKRGDILKETPSTASSRPGTSRVPRSSRRTPSSSTPASRATPGSSRATGLPREPRHSTPATSKAKASSTEAT

>In-frame_GRB2_ENST00000316615_chr17_73389632_-_SS18L1_ENST00000421564_chr20_60747738_+_117aa
MEAIAKTDFKATADDELSFKRGDILKETPSTASSRPGTSRVPRSSRRTPSSSTPASRATPGSSRATGLPREPRHSTPATSKAKASSTEAT

>In-frame_GRB2_ENST00000316615_chr17_73389632_-_SS18L1_ENST00000331758_chr20_60747738_+_117aa
MEAIAKTDFKATADDELSFKRGDILKETPSTASSRPGTSRVPRSSRRTPSSSTPASRATPGSSRATGLPREPRHSTPATSKAKASSTEAT

>In-frame_GRB2_ENST00000316615_chr17_73389632_-_SS18L1_ENST00000370848_chr20_60747738_+_117aa
MEAIAKTDFKATADDELSFKRGDILKETPSTASSRPGTSRVPRSSRRTPSSSTPASRATPGSSRATGLPREPRHSTPATSKAKASSTEAT


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_GRB2_ENST00000392562_chr17_73389632_-_SS18L1_ENST00000421564_chr20_60747738_+_353nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGT
ACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCG
GGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACC

>In-frame_GRB2_ENST00000392562_chr17_73389632_-_SS18L1_ENST00000331758_chr20_60747738_+_353nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGT
ACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCG
GGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACC

>In-frame_GRB2_ENST00000392562_chr17_73389632_-_SS18L1_ENST00000370848_chr20_60747738_+_353nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGT
ACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCG
GGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACC

>In-frame_GRB2_ENST00000316804_chr17_73389632_-_SS18L1_ENST00000421564_chr20_60747738_+_353nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGT
ACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCG
GGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACC

>In-frame_GRB2_ENST00000316804_chr17_73389632_-_SS18L1_ENST00000331758_chr20_60747738_+_353nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGT
ACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCG
GGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACC

>In-frame_GRB2_ENST00000316804_chr17_73389632_-_SS18L1_ENST00000370848_chr20_60747738_+_353nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGT
ACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCG
GGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACC

>In-frame_GRB2_ENST00000316615_chr17_73389632_-_SS18L1_ENST00000421564_chr20_60747738_+_353nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGT
ACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCG
GGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACC

>In-frame_GRB2_ENST00000316615_chr17_73389632_-_SS18L1_ENST00000331758_chr20_60747738_+_353nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGT
ACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCG
GGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACC

>In-frame_GRB2_ENST00000316615_chr17_73389632_-_SS18L1_ENST00000370848_chr20_60747738_+_353nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGT
ACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCG
GGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACC


* Fusion transcript sequences (Full-length transcript).
>In-frame_GRB2_ENST00000392562_chr17_73389632_-_SS18L1_ENST00000421564_chr20_60747738_+_3593nt
GAGTACGGGAGGCTGCGCTCGGCGCCTCTCTCGTGCCTTTTCCTCTTGGCTCTACAGCGGGAGTGGGCCCCGGGGGAACCGGGACCGGCC
CCGGGGTTCGCGTCGGGGCGGCGAGGCTTGGGACGTGGAGCGCAATCCCCGGGGCTCCGGACTCTACGTTTCCCCTTTTGGGGCGCTTCC
TTCCTGGGGACCGTCCTCCTCCGGCTCTTGGCTCTGGGCAGTCCGGGGGAAGAGGTCGGGGTTCTCTGGCGAGGTCCCCTGCCTTCATCG
GGAGGGTTTGCACGGAAGGGGCCCGGGAAGCCCAGGCGGGCCGAACGCCGACCGAGTCAGTCTACCCGAGCCTGGCGGCGGGGGACTGGT
GTGGGCTGCAGCTGTGGTGATTGATGTGCCTTCGACCTGCACGGCAACCACGTCACCATCTCCTGGCGTCTTTGGGCTTAATTTTGTGCG
GGAATCCACTTTGGGGTGGAACGTTTGCTGCTGGAGCCGGGGGAGATACCTTTATTCTGACACTTAAAAAAAAAAACTATTTGAAAAATA
TTTGTCAAGAAAAATTCAGCAGTAGCAGGTTGGACTGCACCGAGGAAGGATTGCGGCGAGAGCGGGCGCTGGTAATTTTCATTTGCAGCG
CGCCCTCTCTATGATTGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTT
GCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTC
AAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGTACAGCCAGCAGCAGGCCGGGTACCAGC
AGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCGGGCAGCAGCAGGGCTACGGGTCTGCCC
AGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACCGAGCACCGCAGACAGCGCCGTCTGCCC
AGCAGCAGCGGCCCTACGGCTATGAACAGGGCCAGTATGGAAATTACCAGCAGTAAGGGACACACATTCTGGCTGGAGCCCTTGTGGTAG
CGTGTTCATCCAGGGGCCGGATGGGCTGGCGGCAGCTCTGGTGAATTGTGACATGTTGGTTACCTGTTCGCCCAGTGCCACGTCTGCATG
TGAAGCGTGCTCATTTCATGCTGGGACCTACTTGCTCAGATCTCCAAGCAAGCATTTCTTTTCTTTTAGGGATGTCTGAAAGTCACATCC
AGTTACATTACTGTGTTCTTTCTAATGAAAAGTAAAGGTTTTATATAGAGAAACTTGAGTAATTTTTACATTTCTAAGACATTAAATCCC
ATTTAAATTCTGTGTGAACATTAAAGACAGCACACTTGCAAAAGTATGGTCAAAGGAAAAAAATCCCACATTTCAATTAACAAGTAGCAT
GGACATTTGATCAACCTTTAGTTGGAATAATAATATTCATATTTGCTATGAATCCTTTTAAAAAAATCTTTGGATAAATGCTGACAGATT
TCCAAGAACTACCAAGAAAATACAAGAGATATCCAATGCTTGATATATGAGGCCTAGTAATAACGATATTTCTCTTTAATTGATGTTTTG
TTTTAAAAGTTAAAAGTAATTCTTGGCGTGGTGGTTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAAGCGGGCGGATCACCTGAGGT
CGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCGTCCCTACTAAAAATACAAAATTAGCCAGGTATGGTGGTGCATACCTGTA
ATCCCAGCTACTCGGGAACCTGAGGCAGGAGAATGGCTTGAACCCAGGAGACAGAGGTTGTGGTGGGGCAAGATCGCACCATTGCACCCG
AGCCTAGGCAACAAGAGTGAAATTCCGTCTCAAAAAAATAAATAAATAAATAAATAAATAAGTTAAAATTAATTCTTTATCCAGAGTCGG
GTGCTTTAGAATTTATAAGTCACTTATGTGTTTTGCTTGAATTAATTCTGACAGCCCCTATGAGGAAATCTGGAGGCAGGTAACAGTTCC
CATTTTAGAGATGAAGAACTGAGGCACAGATTAAAGGACTTGCCTGTGTTGAATACCAGTCCTGTTCTAGGACATTCTCCCCTCTCCTAG
GAGACGGATGTCACGCACAAATGGGGAGAGAAGTGTTTATTTTGTAGGCACTAAGGGTTTCTAAAACCCTTAACACTGGTAAGGGCTCAA
AAATAAACGTATGTGTTCATATTCGATCACCGAAATGAGAGTTCTTAATTGCTAATTGACAAACGCGTTAGCAATTTCAGTTAGGGAGTC
ATCTCCCTTGATTGTGTTCTTTTCCTGTCAATTTTCATAGACCTAATTTGCAAACTCAATCGGGGACTAAAATTTCCCACTGAAAATGTT
AAACATTTTAGATAACTGTGAAGATAGTTTATTTTTATTCCTTGCCAATCTGGGAATATGCCTTTTTTGTGTGTTTGTGTGTTTTTTTAA
GTGCTGTATTAATAATACTTTCTGAAAGAAAAGGACACTTACCCCAAAACTTCAATCTGAAATGTCTTACATTAAGAATATCTTGAATGT
TGTGTATATATTTTAAAAAGCACTTTGCAAAATAGTTTGTACATTTATTTCCTAATTTATACATGATTTTTGGTGTTAATATATTTAATG
ATTAATAACAGAATGTTTATTTAATGTGCTGTCCATTTTTATGTAATATTATGGGGAAAGTGATGCCAGCAGTTCCTTTTCATTATTCTA
TCTTCTGTCATATGAATGTTGAGCAAAGCTTAGGCCAACATGAATTGTTTGTGAAGTGTGGTTGATGGTGCTTTGTTTTTTTCTGACTAC
TTCTATGGAAGGCCAGTGAAGAAGCAAAGGAAGACATGAAAATTGACGCTCATTCTTCTTCCTATTGTTCCCTGACATCCAGCAAATTGT
GAATTTGAAAAATGATGGCCAGTTTTCAGAAGTGCTGACAAATTCATATTGGTATGCAAAAGCTCATCACCCATTAAGGTTTGTTGTTGA
ATCAACAGTACTCAGCATATTAAAACAGTACATCAGAACTCATGCCAACAGTCTTTATGATGGGATTAAGGTGGACAAGATCTCCTAAGA
TCTGTGAATGGGATTAAGGTGGACAAGATCTCCTAAGATCTGAAAAGAAACCTTAATACGCTCATATGGTTGGAGTGTTAAGTGAACCTC
TGATTTTGTCAGGGTTTTTCTACGTGTAGGCGTGAATAGGGGGCACCCCTTCAAAACTGTACAAAGAAGACGACTGTTTTCCATTTCCAT
TTAAACATTTTTAGCCACTTCATTTCTATTTATTGAACAGGTCAAATTTGTCTTGTTATTTGTGAGTACAGTACATTTAAAAAACATCCT

>In-frame_GRB2_ENST00000392562_chr17_73389632_-_SS18L1_ENST00000331758_chr20_60747738_+_4412nt
GAGTACGGGAGGCTGCGCTCGGCGCCTCTCTCGTGCCTTTTCCTCTTGGCTCTACAGCGGGAGTGGGCCCCGGGGGAACCGGGACCGGCC
CCGGGGTTCGCGTCGGGGCGGCGAGGCTTGGGACGTGGAGCGCAATCCCCGGGGCTCCGGACTCTACGTTTCCCCTTTTGGGGCGCTTCC
TTCCTGGGGACCGTCCTCCTCCGGCTCTTGGCTCTGGGCAGTCCGGGGGAAGAGGTCGGGGTTCTCTGGCGAGGTCCCCTGCCTTCATCG
GGAGGGTTTGCACGGAAGGGGCCCGGGAAGCCCAGGCGGGCCGAACGCCGACCGAGTCAGTCTACCCGAGCCTGGCGGCGGGGGACTGGT
GTGGGCTGCAGCTGTGGTGATTGATGTGCCTTCGACCTGCACGGCAACCACGTCACCATCTCCTGGCGTCTTTGGGCTTAATTTTGTGCG
GGAATCCACTTTGGGGTGGAACGTTTGCTGCTGGAGCCGGGGGAGATACCTTTATTCTGACACTTAAAAAAAAAAACTATTTGAAAAATA
TTTGTCAAGAAAAATTCAGCAGTAGCAGGTTGGACTGCACCGAGGAAGGATTGCGGCGAGAGCGGGCGCTGGTAATTTTCATTTGCAGCG
CGCCCTCTCTATGATTGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTT
GCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTC
AAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGTACAGCCAGCAGCAGGCCGGGTACCAGC
AGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCGGGCAGCAGCAGGGCTACGGGTCTGCCC
AGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACCGAGCACCGCAGACAGCGCCGTCTGCCC
AGCAGCAGCGGCCCTACGGCTATGAACAGGGCCAGTATGGAAATTACCAGCAGTAAGGGACACACATTCTGGCTGGAGCCCTTGTGGTAG
CGTGTTCATCCAGGGGCCGGATGGGCTGGCGGCAGCTCTGGTGAATTGTGACATGTTGGTTACCTGTTCGCCCAGTGCCACGTCTGCATG
TGAAGCGTGCTCATTTCATGCTGGGTATGACGCCGAGCGCACACCACTGGCGTGAGACAGCGCTTGGTGGTGTGATACTTTTGGTGCTGT
GTATAGTATTGTATGTCGGTACACGGAGAGGTATCCTTTTTTTGTCCCCCGCCCCCTTCTCAATGTTTCTAGCTAGCTTTGGGGGTCATT
TTGTCATCAGAGCATTCTGTGCCCAGGGACAGGACAGATCTCGAGGACACCACAGTCCACCTGTTCCCGTCAACAGACGTTAGGTCTCAT
TTTCCTCCTCATGCAGTGTTGTAGTGTGGGTTGTCAACTTTTCTTTAACTGGCTACGCCACAGCTGGACACACATGCAGCCCCTGGAGGG
CAGCCTCTTCCTGTGCCTCGATGGGGTGGGTGGGAGGGCATCTTCTGTGCGTTGGGTCAGTTTCTGTTACGTAACGAAAAGGATAAACAT
CTCCCACGGGAGAGGCCACAGATGGCCACTTCCAGAGCTTGCCCATTGCCTGTCTCTCGCCAATTCCGTTTATCCAAAAAGGTACATGTT
TTTGTATTAAAAAGTAAACAGGGATCAGTGACTGTATTCCAAATAAATATGAATCCCTAAGGGCCGTGGACAAATTGCCTAACCCAGGGC
CAGCGGTATTGCTGAAGGAAAGGGGCAGCTCTCTGGGAAGTGGGCCCTCAGAGATTACTCTGGCTTTGACCCTTGTTTAGCTGATGGTCA
TTTCTGGGATTGGAATATTTAATAAGCCCAATTCTAAGTTGATAGGTAATTTTAAATATTCAAACCAAATCTTCCCAACAGTTGGCAAGT
TGTTTATTTTATATTATTTCTTCCAGGACCTACTTGCTCAGATCTCCAAGCAAGCATTTCTTTTCTTTTAGGGATGTCTGAAAGTCACAT
CCAGTTACATTACTGTGTTCTTTCTAATGAAAAGTAAAGGTTTTATATAGAGAAACTTGAGTAATTTTTACATTTCTAAGACATTAAATC
CCATTTAAATTCTGTGTGAACATTAAAGACAGCACACTTGCAAAAGTATGGTCAAAGGAAAAAAATCCCACATTTCAATTAACAAGTAGC
ATGGACATTTGATCAACCTTTAGTTGGAATAATAATATTCATATTTGCTATGAATCCTTTTAAAAAAATCTTTGGATAAATGCTGACAGA
TTTCCAAGAACTACCAAGAAAATACAAGAGATATCCAATGCTTGATATATGAGGCCTAGTAATAACGATATTTCTCTTTAATTGATGTTT
TGTTTTAAAAGTTAAAAGTAATTCTTGGCGTGGTGGTTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAAGCGGGCGGATCACCTGAG
GTCGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCGTCCCTACTAAAAATACAAAATTAGCCAGGTATGGTGGTGCATACCTG
TAATCCCAGCTACTCGGGAACCTGAGGCAGGAGAATGGCTTGAACCCAGGAGACAGAGGTTGTGGTGGGGCAAGATCGCACCATTGCACC
CGAGCCTAGGCAACAAGAGTGAAATTCCGTCTCAAAAAAATAAATAAATAAATAAATAAATAAGTTAAAATTAATTCTTTATCCAGAGTC
GGGTGCTTTAGAATTTATAAGTCACTTATGTGTTTTGCTTGAATTAATTCTGACAGCCCCTATGAGGAAATCTGGAGGCAGGTAACAGTT
CCCATTTTAGAGATGAAGAACTGAGGCACAGATTAAAGGACTTGCCTGTGTTGAATACCAGTCCTGTTCTAGGACATTCTCCCCTCTCCT
AGGAGACGGATGTCACGCACAAATGGGGAGAGAAGTGTTTATTTTGTAGGCACTAAGGGTTTCTAAAACCCTTAACACTGGTAAGGGCTC
AAAAATAAACGTATGTGTTCATATTCGATCACCGAAATGAGAGTTCTTAATTGCTAATTGACAAACGCGTTAGCAATTTCAGTTAGGGAG
TCATCTCCCTTGATTGTGTTCTTTTCCTGTCAATTTTCATAGACCTAATTTGCAAACTCAATCGGGGACTAAAATTTCCCACTGAAAATG
TTAAACATTTTAGATAACTGTGAAGATAGTTTATTTTTATTCCTTGCCAATCTGGGAATATGCCTTTTTTGTGTGTTTGTGTGTTTTTTT
AAGTGCTGTATTAATAATACTTTCTGAAAGAAAAGGACACTTACCCCAAAACTTCAATCTGAAATGTCTTACATTAAGAATATCTTGAAT
GTTGTGTATATATTTTAAAAAGCACTTTGCAAAATAGTTTGTACATTTATTTCCTAATTTATACATGATTTTTGGTGTTAATATATTTAA
TGATTAATAACAGAATGTTTATTTAATGTGCTGTCCATTTTTATGTAATATTATGGGGAAAGTGATGCCAGCAGTTCCTTTTCATTATTC
TATCTTCTGTCATATGAATGTTGAGCAAAGCTTAGGCCAACATGAATTGTTTGTGAAGTGTGGTTGATGGTGCTTTGTTTTTTTCTGACT
ACTTCTATGGAAGGCCAGTGAAGAAGCAAAGGAAGACATGAAAATTGACGCTCATTCTTCTTCCTATTGTTCCCTGACATCCAGCAAATT
GTGAATTTGAAAAATGATGGCCAGTTTTCAGAAGTGCTGACAAATTCATATTGGTATGCAAAAGCTCATCACCCATTAAGGTTTGTTGTT
GAATCAACAGTACTCAGCATATTAAAACAGTACATCAGAACTCATGCCAACAGTCTTTATGATGGGATTAAGGTGGACAAGATCTCCTAA
GATCTGTGAATGGGATTAAGGTGGACAAGATCTCCTAAGATCTGAAAAGAAACCTTAATACGCTCATATGGTTGGAGTGTTAAGTGAACC
TCTGATTTTGTCAGGGTTTTTCTACGTGTAGGCGTGAATAGGGGGCACCCCTTCAAAACTGTACAAAGAAGACGACTGTTTTCCATTTCC
ATTTAAACATTTTTAGCCACTTCATTTCTATTTATTGAACAGGTCAAATTTGTCTTGTTATTTGTGAGTACAGTACATTTAAAAAACATC
CTTATCGGTTATTTTTTTTTCAGTCGGAGTTTGACGTATAAATTGTTTATGCTTTTGGTGTAATCTCTTAATAAACTGGTTCTTCAAAAA

>In-frame_GRB2_ENST00000392562_chr17_73389632_-_SS18L1_ENST00000370848_chr20_60747738_+_3593nt
GAGTACGGGAGGCTGCGCTCGGCGCCTCTCTCGTGCCTTTTCCTCTTGGCTCTACAGCGGGAGTGGGCCCCGGGGGAACCGGGACCGGCC
CCGGGGTTCGCGTCGGGGCGGCGAGGCTTGGGACGTGGAGCGCAATCCCCGGGGCTCCGGACTCTACGTTTCCCCTTTTGGGGCGCTTCC
TTCCTGGGGACCGTCCTCCTCCGGCTCTTGGCTCTGGGCAGTCCGGGGGAAGAGGTCGGGGTTCTCTGGCGAGGTCCCCTGCCTTCATCG
GGAGGGTTTGCACGGAAGGGGCCCGGGAAGCCCAGGCGGGCCGAACGCCGACCGAGTCAGTCTACCCGAGCCTGGCGGCGGGGGACTGGT
GTGGGCTGCAGCTGTGGTGATTGATGTGCCTTCGACCTGCACGGCAACCACGTCACCATCTCCTGGCGTCTTTGGGCTTAATTTTGTGCG
GGAATCCACTTTGGGGTGGAACGTTTGCTGCTGGAGCCGGGGGAGATACCTTTATTCTGACACTTAAAAAAAAAAACTATTTGAAAAATA
TTTGTCAAGAAAAATTCAGCAGTAGCAGGTTGGACTGCACCGAGGAAGGATTGCGGCGAGAGCGGGCGCTGGTAATTTTCATTTGCAGCG
CGCCCTCTCTATGATTGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTT
GCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTC
AAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGTACAGCCAGCAGCAGGCCGGGTACCAGC
AGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCGGGCAGCAGCAGGGCTACGGGTCTGCCC
AGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACCGAGCACCGCAGACAGCGCCGTCTGCCC
AGCAGCAGCGGCCCTACGGCTATGAACAGGGCCAGTATGGAAATTACCAGCAGTAAGGGACACACATTCTGGCTGGAGCCCTTGTGGTAG
CGTGTTCATCCAGGGGCCGGATGGGCTGGCGGCAGCTCTGGTGAATTGTGACATGTTGGTTACCTGTTCGCCCAGTGCCACGTCTGCATG
TGAAGCGTGCTCATTTCATGCTGGGACCTACTTGCTCAGATCTCCAAGCAAGCATTTCTTTTCTTTTAGGGATGTCTGAAAGTCACATCC
AGTTACATTACTGTGTTCTTTCTAATGAAAAGTAAAGGTTTTATATAGAGAAACTTGAGTAATTTTTACATTTCTAAGACATTAAATCCC
ATTTAAATTCTGTGTGAACATTAAAGACAGCACACTTGCAAAAGTATGGTCAAAGGAAAAAAATCCCACATTTCAATTAACAAGTAGCAT
GGACATTTGATCAACCTTTAGTTGGAATAATAATATTCATATTTGCTATGAATCCTTTTAAAAAAATCTTTGGATAAATGCTGACAGATT
TCCAAGAACTACCAAGAAAATACAAGAGATATCCAATGCTTGATATATGAGGCCTAGTAATAACGATATTTCTCTTTAATTGATGTTTTG
TTTTAAAAGTTAAAAGTAATTCTTGGCGTGGTGGTTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAAGCGGGCGGATCACCTGAGGT
CGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCGTCCCTACTAAAAATACAAAATTAGCCAGGTATGGTGGTGCATACCTGTA
ATCCCAGCTACTCGGGAACCTGAGGCAGGAGAATGGCTTGAACCCAGGAGACAGAGGTTGTGGTGGGGCAAGATCGCACCATTGCACCCG
AGCCTAGGCAACAAGAGTGAAATTCCGTCTCAAAAAAATAAATAAATAAATAAATAAATAAGTTAAAATTAATTCTTTATCCAGAGTCGG
GTGCTTTAGAATTTATAAGTCACTTATGTGTTTTGCTTGAATTAATTCTGACAGCCCCTATGAGGAAATCTGGAGGCAGGTAACAGTTCC
CATTTTAGAGATGAAGAACTGAGGCACAGATTAAAGGACTTGCCTGTGTTGAATACCAGTCCTGTTCTAGGACATTCTCCCCTCTCCTAG
GAGACGGATGTCACGCACAAATGGGGAGAGAAGTGTTTATTTTGTAGGCACTAAGGGTTTCTAAAACCCTTAACACTGGTAAGGGCTCAA
AAATAAACGTATGTGTTCATATTCGATCACCGAAATGAGAGTTCTTAATTGCTAATTGACAAACGCGTTAGCAATTTCAGTTAGGGAGTC
ATCTCCCTTGATTGTGTTCTTTTCCTGTCAATTTTCATAGACCTAATTTGCAAACTCAATCGGGGACTAAAATTTCCCACTGAAAATGTT
AAACATTTTAGATAACTGTGAAGATAGTTTATTTTTATTCCTTGCCAATCTGGGAATATGCCTTTTTTGTGTGTTTGTGTGTTTTTTTAA
GTGCTGTATTAATAATACTTTCTGAAAGAAAAGGACACTTACCCCAAAACTTCAATCTGAAATGTCTTACATTAAGAATATCTTGAATGT
TGTGTATATATTTTAAAAAGCACTTTGCAAAATAGTTTGTACATTTATTTCCTAATTTATACATGATTTTTGGTGTTAATATATTTAATG
ATTAATAACAGAATGTTTATTTAATGTGCTGTCCATTTTTATGTAATATTATGGGGAAAGTGATGCCAGCAGTTCCTTTTCATTATTCTA
TCTTCTGTCATATGAATGTTGAGCAAAGCTTAGGCCAACATGAATTGTTTGTGAAGTGTGGTTGATGGTGCTTTGTTTTTTTCTGACTAC
TTCTATGGAAGGCCAGTGAAGAAGCAAAGGAAGACATGAAAATTGACGCTCATTCTTCTTCCTATTGTTCCCTGACATCCAGCAAATTGT
GAATTTGAAAAATGATGGCCAGTTTTCAGAAGTGCTGACAAATTCATATTGGTATGCAAAAGCTCATCACCCATTAAGGTTTGTTGTTGA
ATCAACAGTACTCAGCATATTAAAACAGTACATCAGAACTCATGCCAACAGTCTTTATGATGGGATTAAGGTGGACAAGATCTCCTAAGA
TCTGTGAATGGGATTAAGGTGGACAAGATCTCCTAAGATCTGAAAAGAAACCTTAATACGCTCATATGGTTGGAGTGTTAAGTGAACCTC
TGATTTTGTCAGGGTTTTTCTACGTGTAGGCGTGAATAGGGGGCACCCCTTCAAAACTGTACAAAGAAGACGACTGTTTTCCATTTCCAT
TTAAACATTTTTAGCCACTTCATTTCTATTTATTGAACAGGTCAAATTTGTCTTGTTATTTGTGAGTACAGTACATTTAAAAAACATCCT

>In-frame_GRB2_ENST00000316804_chr17_73389632_-_SS18L1_ENST00000421564_chr20_60747738_+_3112nt
GACCGGGCGGCGGCAGCGGCGGCGGCGGCTGTGGCAGAGTCTGTGCCTGTGGCGGTGACGGCGGCGGGAGCAAGCGCTGCCCTCGCAGAG
CAGCCTTGGGGTCGCCGGCCGCTCGCAGCGTTGTGGAGGGGCGGGCCGGACGCTGAGCGGAGCAGCTGCGCCACGGGTGGCATTGTGTGT
CCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGC
TTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCA
AAAGGGGGGACATCCTCAAGGAAACTCCCAGTACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCA
GCAGCAGTACCCCAGCCAGCAGAGCTACCCCGGGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCA
GCAAGGCCAAGGCCAGCAGTACGGAAGCTACCGAGCACCGCAGACAGCGCCGTCTGCCCAGCAGCAGCGGCCCTACGGCTATGAACAGGG
CCAGTATGGAAATTACCAGCAGTAAGGGACACACATTCTGGCTGGAGCCCTTGTGGTAGCGTGTTCATCCAGGGGCCGGATGGGCTGGCG
GCAGCTCTGGTGAATTGTGACATGTTGGTTACCTGTTCGCCCAGTGCCACGTCTGCATGTGAAGCGTGCTCATTTCATGCTGGGACCTAC
TTGCTCAGATCTCCAAGCAAGCATTTCTTTTCTTTTAGGGATGTCTGAAAGTCACATCCAGTTACATTACTGTGTTCTTTCTAATGAAAA
GTAAAGGTTTTATATAGAGAAACTTGAGTAATTTTTACATTTCTAAGACATTAAATCCCATTTAAATTCTGTGTGAACATTAAAGACAGC
ACACTTGCAAAAGTATGGTCAAAGGAAAAAAATCCCACATTTCAATTAACAAGTAGCATGGACATTTGATCAACCTTTAGTTGGAATAAT
AATATTCATATTTGCTATGAATCCTTTTAAAAAAATCTTTGGATAAATGCTGACAGATTTCCAAGAACTACCAAGAAAATACAAGAGATA
TCCAATGCTTGATATATGAGGCCTAGTAATAACGATATTTCTCTTTAATTGATGTTTTGTTTTAAAAGTTAAAAGTAATTCTTGGCGTGG
TGGTTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAAGCGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACATGG
AGAAACCCCGTCCCTACTAAAAATACAAAATTAGCCAGGTATGGTGGTGCATACCTGTAATCCCAGCTACTCGGGAACCTGAGGCAGGAG
AATGGCTTGAACCCAGGAGACAGAGGTTGTGGTGGGGCAAGATCGCACCATTGCACCCGAGCCTAGGCAACAAGAGTGAAATTCCGTCTC
AAAAAAATAAATAAATAAATAAATAAATAAGTTAAAATTAATTCTTTATCCAGAGTCGGGTGCTTTAGAATTTATAAGTCACTTATGTGT
TTTGCTTGAATTAATTCTGACAGCCCCTATGAGGAAATCTGGAGGCAGGTAACAGTTCCCATTTTAGAGATGAAGAACTGAGGCACAGAT
TAAAGGACTTGCCTGTGTTGAATACCAGTCCTGTTCTAGGACATTCTCCCCTCTCCTAGGAGACGGATGTCACGCACAAATGGGGAGAGA
AGTGTTTATTTTGTAGGCACTAAGGGTTTCTAAAACCCTTAACACTGGTAAGGGCTCAAAAATAAACGTATGTGTTCATATTCGATCACC
GAAATGAGAGTTCTTAATTGCTAATTGACAAACGCGTTAGCAATTTCAGTTAGGGAGTCATCTCCCTTGATTGTGTTCTTTTCCTGTCAA
TTTTCATAGACCTAATTTGCAAACTCAATCGGGGACTAAAATTTCCCACTGAAAATGTTAAACATTTTAGATAACTGTGAAGATAGTTTA
TTTTTATTCCTTGCCAATCTGGGAATATGCCTTTTTTGTGTGTTTGTGTGTTTTTTTAAGTGCTGTATTAATAATACTTTCTGAAAGAAA
AGGACACTTACCCCAAAACTTCAATCTGAAATGTCTTACATTAAGAATATCTTGAATGTTGTGTATATATTTTAAAAAGCACTTTGCAAA
ATAGTTTGTACATTTATTTCCTAATTTATACATGATTTTTGGTGTTAATATATTTAATGATTAATAACAGAATGTTTATTTAATGTGCTG
TCCATTTTTATGTAATATTATGGGGAAAGTGATGCCAGCAGTTCCTTTTCATTATTCTATCTTCTGTCATATGAATGTTGAGCAAAGCTT
AGGCCAACATGAATTGTTTGTGAAGTGTGGTTGATGGTGCTTTGTTTTTTTCTGACTACTTCTATGGAAGGCCAGTGAAGAAGCAAAGGA
AGACATGAAAATTGACGCTCATTCTTCTTCCTATTGTTCCCTGACATCCAGCAAATTGTGAATTTGAAAAATGATGGCCAGTTTTCAGAA
GTGCTGACAAATTCATATTGGTATGCAAAAGCTCATCACCCATTAAGGTTTGTTGTTGAATCAACAGTACTCAGCATATTAAAACAGTAC
ATCAGAACTCATGCCAACAGTCTTTATGATGGGATTAAGGTGGACAAGATCTCCTAAGATCTGTGAATGGGATTAAGGTGGACAAGATCT
CCTAAGATCTGAAAAGAAACCTTAATACGCTCATATGGTTGGAGTGTTAAGTGAACCTCTGATTTTGTCAGGGTTTTTCTACGTGTAGGC
GTGAATAGGGGGCACCCCTTCAAAACTGTACAAAGAAGACGACTGTTTTCCATTTCCATTTAAACATTTTTAGCCACTTCATTTCTATTT
ATTGAACAGGTCAAATTTGTCTTGTTATTTGTGAGTACAGTACATTTAAAAAACATCCTTATCGGTTATTTTTTTTTCAGTCGGAGTTTG

>In-frame_GRB2_ENST00000316804_chr17_73389632_-_SS18L1_ENST00000331758_chr20_60747738_+_3931nt
GACCGGGCGGCGGCAGCGGCGGCGGCGGCTGTGGCAGAGTCTGTGCCTGTGGCGGTGACGGCGGCGGGAGCAAGCGCTGCCCTCGCAGAG
CAGCCTTGGGGTCGCCGGCCGCTCGCAGCGTTGTGGAGGGGCGGGCCGGACGCTGAGCGGAGCAGCTGCGCCACGGGTGGCATTGTGTGT
CCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGC
TTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCA
AAAGGGGGGACATCCTCAAGGAAACTCCCAGTACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCA
GCAGCAGTACCCCAGCCAGCAGAGCTACCCCGGGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCA
GCAAGGCCAAGGCCAGCAGTACGGAAGCTACCGAGCACCGCAGACAGCGCCGTCTGCCCAGCAGCAGCGGCCCTACGGCTATGAACAGGG
CCAGTATGGAAATTACCAGCAGTAAGGGACACACATTCTGGCTGGAGCCCTTGTGGTAGCGTGTTCATCCAGGGGCCGGATGGGCTGGCG
GCAGCTCTGGTGAATTGTGACATGTTGGTTACCTGTTCGCCCAGTGCCACGTCTGCATGTGAAGCGTGCTCATTTCATGCTGGGTATGAC
GCCGAGCGCACACCACTGGCGTGAGACAGCGCTTGGTGGTGTGATACTTTTGGTGCTGTGTATAGTATTGTATGTCGGTACACGGAGAGG
TATCCTTTTTTTGTCCCCCGCCCCCTTCTCAATGTTTCTAGCTAGCTTTGGGGGTCATTTTGTCATCAGAGCATTCTGTGCCCAGGGACA
GGACAGATCTCGAGGACACCACAGTCCACCTGTTCCCGTCAACAGACGTTAGGTCTCATTTTCCTCCTCATGCAGTGTTGTAGTGTGGGT
TGTCAACTTTTCTTTAACTGGCTACGCCACAGCTGGACACACATGCAGCCCCTGGAGGGCAGCCTCTTCCTGTGCCTCGATGGGGTGGGT
GGGAGGGCATCTTCTGTGCGTTGGGTCAGTTTCTGTTACGTAACGAAAAGGATAAACATCTCCCACGGGAGAGGCCACAGATGGCCACTT
CCAGAGCTTGCCCATTGCCTGTCTCTCGCCAATTCCGTTTATCCAAAAAGGTACATGTTTTTGTATTAAAAAGTAAACAGGGATCAGTGA
CTGTATTCCAAATAAATATGAATCCCTAAGGGCCGTGGACAAATTGCCTAACCCAGGGCCAGCGGTATTGCTGAAGGAAAGGGGCAGCTC
TCTGGGAAGTGGGCCCTCAGAGATTACTCTGGCTTTGACCCTTGTTTAGCTGATGGTCATTTCTGGGATTGGAATATTTAATAAGCCCAA
TTCTAAGTTGATAGGTAATTTTAAATATTCAAACCAAATCTTCCCAACAGTTGGCAAGTTGTTTATTTTATATTATTTCTTCCAGGACCT
ACTTGCTCAGATCTCCAAGCAAGCATTTCTTTTCTTTTAGGGATGTCTGAAAGTCACATCCAGTTACATTACTGTGTTCTTTCTAATGAA
AAGTAAAGGTTTTATATAGAGAAACTTGAGTAATTTTTACATTTCTAAGACATTAAATCCCATTTAAATTCTGTGTGAACATTAAAGACA
GCACACTTGCAAAAGTATGGTCAAAGGAAAAAAATCCCACATTTCAATTAACAAGTAGCATGGACATTTGATCAACCTTTAGTTGGAATA
ATAATATTCATATTTGCTATGAATCCTTTTAAAAAAATCTTTGGATAAATGCTGACAGATTTCCAAGAACTACCAAGAAAATACAAGAGA
TATCCAATGCTTGATATATGAGGCCTAGTAATAACGATATTTCTCTTTAATTGATGTTTTGTTTTAAAAGTTAAAAGTAATTCTTGGCGT
GGTGGTTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAAGCGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACAT
GGAGAAACCCCGTCCCTACTAAAAATACAAAATTAGCCAGGTATGGTGGTGCATACCTGTAATCCCAGCTACTCGGGAACCTGAGGCAGG
AGAATGGCTTGAACCCAGGAGACAGAGGTTGTGGTGGGGCAAGATCGCACCATTGCACCCGAGCCTAGGCAACAAGAGTGAAATTCCGTC
TCAAAAAAATAAATAAATAAATAAATAAATAAGTTAAAATTAATTCTTTATCCAGAGTCGGGTGCTTTAGAATTTATAAGTCACTTATGT
GTTTTGCTTGAATTAATTCTGACAGCCCCTATGAGGAAATCTGGAGGCAGGTAACAGTTCCCATTTTAGAGATGAAGAACTGAGGCACAG
ATTAAAGGACTTGCCTGTGTTGAATACCAGTCCTGTTCTAGGACATTCTCCCCTCTCCTAGGAGACGGATGTCACGCACAAATGGGGAGA
GAAGTGTTTATTTTGTAGGCACTAAGGGTTTCTAAAACCCTTAACACTGGTAAGGGCTCAAAAATAAACGTATGTGTTCATATTCGATCA
CCGAAATGAGAGTTCTTAATTGCTAATTGACAAACGCGTTAGCAATTTCAGTTAGGGAGTCATCTCCCTTGATTGTGTTCTTTTCCTGTC
AATTTTCATAGACCTAATTTGCAAACTCAATCGGGGACTAAAATTTCCCACTGAAAATGTTAAACATTTTAGATAACTGTGAAGATAGTT
TATTTTTATTCCTTGCCAATCTGGGAATATGCCTTTTTTGTGTGTTTGTGTGTTTTTTTAAGTGCTGTATTAATAATACTTTCTGAAAGA
AAAGGACACTTACCCCAAAACTTCAATCTGAAATGTCTTACATTAAGAATATCTTGAATGTTGTGTATATATTTTAAAAAGCACTTTGCA
AAATAGTTTGTACATTTATTTCCTAATTTATACATGATTTTTGGTGTTAATATATTTAATGATTAATAACAGAATGTTTATTTAATGTGC
TGTCCATTTTTATGTAATATTATGGGGAAAGTGATGCCAGCAGTTCCTTTTCATTATTCTATCTTCTGTCATATGAATGTTGAGCAAAGC
TTAGGCCAACATGAATTGTTTGTGAAGTGTGGTTGATGGTGCTTTGTTTTTTTCTGACTACTTCTATGGAAGGCCAGTGAAGAAGCAAAG
GAAGACATGAAAATTGACGCTCATTCTTCTTCCTATTGTTCCCTGACATCCAGCAAATTGTGAATTTGAAAAATGATGGCCAGTTTTCAG
AAGTGCTGACAAATTCATATTGGTATGCAAAAGCTCATCACCCATTAAGGTTTGTTGTTGAATCAACAGTACTCAGCATATTAAAACAGT
ACATCAGAACTCATGCCAACAGTCTTTATGATGGGATTAAGGTGGACAAGATCTCCTAAGATCTGTGAATGGGATTAAGGTGGACAAGAT
CTCCTAAGATCTGAAAAGAAACCTTAATACGCTCATATGGTTGGAGTGTTAAGTGAACCTCTGATTTTGTCAGGGTTTTTCTACGTGTAG
GCGTGAATAGGGGGCACCCCTTCAAAACTGTACAAAGAAGACGACTGTTTTCCATTTCCATTTAAACATTTTTAGCCACTTCATTTCTAT
TTATTGAACAGGTCAAATTTGTCTTGTTATTTGTGAGTACAGTACATTTAAAAAACATCCTTATCGGTTATTTTTTTTTCAGTCGGAGTT

>In-frame_GRB2_ENST00000316804_chr17_73389632_-_SS18L1_ENST00000370848_chr20_60747738_+_3112nt
GACCGGGCGGCGGCAGCGGCGGCGGCGGCTGTGGCAGAGTCTGTGCCTGTGGCGGTGACGGCGGCGGGAGCAAGCGCTGCCCTCGCAGAG
CAGCCTTGGGGTCGCCGGCCGCTCGCAGCGTTGTGGAGGGGCGGGCCGGACGCTGAGCGGAGCAGCTGCGCCACGGGTGGCATTGTGTGT
CCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGC
TTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCA
AAAGGGGGGACATCCTCAAGGAAACTCCCAGTACAGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCA
GCAGCAGTACCCCAGCCAGCAGAGCTACCCCGGGCAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCA
GCAAGGCCAAGGCCAGCAGTACGGAAGCTACCGAGCACCGCAGACAGCGCCGTCTGCCCAGCAGCAGCGGCCCTACGGCTATGAACAGGG
CCAGTATGGAAATTACCAGCAGTAAGGGACACACATTCTGGCTGGAGCCCTTGTGGTAGCGTGTTCATCCAGGGGCCGGATGGGCTGGCG
GCAGCTCTGGTGAATTGTGACATGTTGGTTACCTGTTCGCCCAGTGCCACGTCTGCATGTGAAGCGTGCTCATTTCATGCTGGGACCTAC
TTGCTCAGATCTCCAAGCAAGCATTTCTTTTCTTTTAGGGATGTCTGAAAGTCACATCCAGTTACATTACTGTGTTCTTTCTAATGAAAA
GTAAAGGTTTTATATAGAGAAACTTGAGTAATTTTTACATTTCTAAGACATTAAATCCCATTTAAATTCTGTGTGAACATTAAAGACAGC
ACACTTGCAAAAGTATGGTCAAAGGAAAAAAATCCCACATTTCAATTAACAAGTAGCATGGACATTTGATCAACCTTTAGTTGGAATAAT
AATATTCATATTTGCTATGAATCCTTTTAAAAAAATCTTTGGATAAATGCTGACAGATTTCCAAGAACTACCAAGAAAATACAAGAGATA
TCCAATGCTTGATATATGAGGCCTAGTAATAACGATATTTCTCTTTAATTGATGTTTTGTTTTAAAAGTTAAAAGTAATTCTTGGCGTGG
TGGTTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAAGCGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACATGG
AGAAACCCCGTCCCTACTAAAAATACAAAATTAGCCAGGTATGGTGGTGCATACCTGTAATCCCAGCTACTCGGGAACCTGAGGCAGGAG
AATGGCTTGAACCCAGGAGACAGAGGTTGTGGTGGGGCAAGATCGCACCATTGCACCCGAGCCTAGGCAACAAGAGTGAAATTCCGTCTC
AAAAAAATAAATAAATAAATAAATAAATAAGTTAAAATTAATTCTTTATCCAGAGTCGGGTGCTTTAGAATTTATAAGTCACTTATGTGT
TTTGCTTGAATTAATTCTGACAGCCCCTATGAGGAAATCTGGAGGCAGGTAACAGTTCCCATTTTAGAGATGAAGAACTGAGGCACAGAT
TAAAGGACTTGCCTGTGTTGAATACCAGTCCTGTTCTAGGACATTCTCCCCTCTCCTAGGAGACGGATGTCACGCACAAATGGGGAGAGA
AGTGTTTATTTTGTAGGCACTAAGGGTTTCTAAAACCCTTAACACTGGTAAGGGCTCAAAAATAAACGTATGTGTTCATATTCGATCACC
GAAATGAGAGTTCTTAATTGCTAATTGACAAACGCGTTAGCAATTTCAGTTAGGGAGTCATCTCCCTTGATTGTGTTCTTTTCCTGTCAA
TTTTCATAGACCTAATTTGCAAACTCAATCGGGGACTAAAATTTCCCACTGAAAATGTTAAACATTTTAGATAACTGTGAAGATAGTTTA
TTTTTATTCCTTGCCAATCTGGGAATATGCCTTTTTTGTGTGTTTGTGTGTTTTTTTAAGTGCTGTATTAATAATACTTTCTGAAAGAAA
AGGACACTTACCCCAAAACTTCAATCTGAAATGTCTTACATTAAGAATATCTTGAATGTTGTGTATATATTTTAAAAAGCACTTTGCAAA
ATAGTTTGTACATTTATTTCCTAATTTATACATGATTTTTGGTGTTAATATATTTAATGATTAATAACAGAATGTTTATTTAATGTGCTG
TCCATTTTTATGTAATATTATGGGGAAAGTGATGCCAGCAGTTCCTTTTCATTATTCTATCTTCTGTCATATGAATGTTGAGCAAAGCTT
AGGCCAACATGAATTGTTTGTGAAGTGTGGTTGATGGTGCTTTGTTTTTTTCTGACTACTTCTATGGAAGGCCAGTGAAGAAGCAAAGGA
AGACATGAAAATTGACGCTCATTCTTCTTCCTATTGTTCCCTGACATCCAGCAAATTGTGAATTTGAAAAATGATGGCCAGTTTTCAGAA
GTGCTGACAAATTCATATTGGTATGCAAAAGCTCATCACCCATTAAGGTTTGTTGTTGAATCAACAGTACTCAGCATATTAAAACAGTAC
ATCAGAACTCATGCCAACAGTCTTTATGATGGGATTAAGGTGGACAAGATCTCCTAAGATCTGTGAATGGGATTAAGGTGGACAAGATCT
CCTAAGATCTGAAAAGAAACCTTAATACGCTCATATGGTTGGAGTGTTAAGTGAACCTCTGATTTTGTCAGGGTTTTTCTACGTGTAGGC
GTGAATAGGGGGCACCCCTTCAAAACTGTACAAAGAAGACGACTGTTTTCCATTTCCATTTAAACATTTTTAGCCACTTCATTTCTATTT
ATTGAACAGGTCAAATTTGTCTTGTTATTTGTGAGTACAGTACATTTAAAAAACATCCTTATCGGTTATTTTTTTTTCAGTCGGAGTTTG

>In-frame_GRB2_ENST00000316615_chr17_73389632_-_SS18L1_ENST00000421564_chr20_60747738_+_3168nt
AAGTTCTCGCGGGACACCGACGGGGAGCGGAAGCCAGGAGGTATTGCTGCTTCGGCGACCGGGCGGCGGCAGCGGCGGCGGCGGCTGTGG
CAGAGTCTGTGCCTGTGGCGGTGACGGCGGCGGGAGCAAGCGCTGCCCTCGCAGAGCAGCCTTGGGGTCGCCGGCCGCTCGCAGCGTTGT
GGAGGGGCGGGCCGGACGCTGAGCGGAGCAGCTGCGCCACGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGC
GAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAAT
GGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGTAC
AGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCGGG
CAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACCGA
GCACCGCAGACAGCGCCGTCTGCCCAGCAGCAGCGGCCCTACGGCTATGAACAGGGCCAGTATGGAAATTACCAGCAGTAAGGGACACAC
ATTCTGGCTGGAGCCCTTGTGGTAGCGTGTTCATCCAGGGGCCGGATGGGCTGGCGGCAGCTCTGGTGAATTGTGACATGTTGGTTACCT
GTTCGCCCAGTGCCACGTCTGCATGTGAAGCGTGCTCATTTCATGCTGGGACCTACTTGCTCAGATCTCCAAGCAAGCATTTCTTTTCTT
TTAGGGATGTCTGAAAGTCACATCCAGTTACATTACTGTGTTCTTTCTAATGAAAAGTAAAGGTTTTATATAGAGAAACTTGAGTAATTT
TTACATTTCTAAGACATTAAATCCCATTTAAATTCTGTGTGAACATTAAAGACAGCACACTTGCAAAAGTATGGTCAAAGGAAAAAAATC
CCACATTTCAATTAACAAGTAGCATGGACATTTGATCAACCTTTAGTTGGAATAATAATATTCATATTTGCTATGAATCCTTTTAAAAAA
ATCTTTGGATAAATGCTGACAGATTTCCAAGAACTACCAAGAAAATACAAGAGATATCCAATGCTTGATATATGAGGCCTAGTAATAACG
ATATTTCTCTTTAATTGATGTTTTGTTTTAAAAGTTAAAAGTAATTCTTGGCGTGGTGGTTCACGCCTGTAATCCCAGCACTTTGGGAGG
CCGAAGCGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCGTCCCTACTAAAAATACAAAATTAG
CCAGGTATGGTGGTGCATACCTGTAATCCCAGCTACTCGGGAACCTGAGGCAGGAGAATGGCTTGAACCCAGGAGACAGAGGTTGTGGTG
GGGCAAGATCGCACCATTGCACCCGAGCCTAGGCAACAAGAGTGAAATTCCGTCTCAAAAAAATAAATAAATAAATAAATAAATAAGTTA
AAATTAATTCTTTATCCAGAGTCGGGTGCTTTAGAATTTATAAGTCACTTATGTGTTTTGCTTGAATTAATTCTGACAGCCCCTATGAGG
AAATCTGGAGGCAGGTAACAGTTCCCATTTTAGAGATGAAGAACTGAGGCACAGATTAAAGGACTTGCCTGTGTTGAATACCAGTCCTGT
TCTAGGACATTCTCCCCTCTCCTAGGAGACGGATGTCACGCACAAATGGGGAGAGAAGTGTTTATTTTGTAGGCACTAAGGGTTTCTAAA
ACCCTTAACACTGGTAAGGGCTCAAAAATAAACGTATGTGTTCATATTCGATCACCGAAATGAGAGTTCTTAATTGCTAATTGACAAACG
CGTTAGCAATTTCAGTTAGGGAGTCATCTCCCTTGATTGTGTTCTTTTCCTGTCAATTTTCATAGACCTAATTTGCAAACTCAATCGGGG
ACTAAAATTTCCCACTGAAAATGTTAAACATTTTAGATAACTGTGAAGATAGTTTATTTTTATTCCTTGCCAATCTGGGAATATGCCTTT
TTTGTGTGTTTGTGTGTTTTTTTAAGTGCTGTATTAATAATACTTTCTGAAAGAAAAGGACACTTACCCCAAAACTTCAATCTGAAATGT
CTTACATTAAGAATATCTTGAATGTTGTGTATATATTTTAAAAAGCACTTTGCAAAATAGTTTGTACATTTATTTCCTAATTTATACATG
ATTTTTGGTGTTAATATATTTAATGATTAATAACAGAATGTTTATTTAATGTGCTGTCCATTTTTATGTAATATTATGGGGAAAGTGATG
CCAGCAGTTCCTTTTCATTATTCTATCTTCTGTCATATGAATGTTGAGCAAAGCTTAGGCCAACATGAATTGTTTGTGAAGTGTGGTTGA
TGGTGCTTTGTTTTTTTCTGACTACTTCTATGGAAGGCCAGTGAAGAAGCAAAGGAAGACATGAAAATTGACGCTCATTCTTCTTCCTAT
TGTTCCCTGACATCCAGCAAATTGTGAATTTGAAAAATGATGGCCAGTTTTCAGAAGTGCTGACAAATTCATATTGGTATGCAAAAGCTC
ATCACCCATTAAGGTTTGTTGTTGAATCAACAGTACTCAGCATATTAAAACAGTACATCAGAACTCATGCCAACAGTCTTTATGATGGGA
TTAAGGTGGACAAGATCTCCTAAGATCTGTGAATGGGATTAAGGTGGACAAGATCTCCTAAGATCTGAAAAGAAACCTTAATACGCTCAT
ATGGTTGGAGTGTTAAGTGAACCTCTGATTTTGTCAGGGTTTTTCTACGTGTAGGCGTGAATAGGGGGCACCCCTTCAAAACTGTACAAA
GAAGACGACTGTTTTCCATTTCCATTTAAACATTTTTAGCCACTTCATTTCTATTTATTGAACAGGTCAAATTTGTCTTGTTATTTGTGA
GTACAGTACATTTAAAAAACATCCTTATCGGTTATTTTTTTTTCAGTCGGAGTTTGACGTATAAATTGTTTATGCTTTTGGTGTAATCTC

>In-frame_GRB2_ENST00000316615_chr17_73389632_-_SS18L1_ENST00000331758_chr20_60747738_+_3987nt
AAGTTCTCGCGGGACACCGACGGGGAGCGGAAGCCAGGAGGTATTGCTGCTTCGGCGACCGGGCGGCGGCAGCGGCGGCGGCGGCTGTGG
CAGAGTCTGTGCCTGTGGCGGTGACGGCGGCGGGAGCAAGCGCTGCCCTCGCAGAGCAGCCTTGGGGTCGCCGGCCGCTCGCAGCGTTGT
GGAGGGGCGGGCCGGACGCTGAGCGGAGCAGCTGCGCCACGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGC
GAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAAT
GGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGTAC
AGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCGGG
CAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACCGA
GCACCGCAGACAGCGCCGTCTGCCCAGCAGCAGCGGCCCTACGGCTATGAACAGGGCCAGTATGGAAATTACCAGCAGTAAGGGACACAC
ATTCTGGCTGGAGCCCTTGTGGTAGCGTGTTCATCCAGGGGCCGGATGGGCTGGCGGCAGCTCTGGTGAATTGTGACATGTTGGTTACCT
GTTCGCCCAGTGCCACGTCTGCATGTGAAGCGTGCTCATTTCATGCTGGGTATGACGCCGAGCGCACACCACTGGCGTGAGACAGCGCTT
GGTGGTGTGATACTTTTGGTGCTGTGTATAGTATTGTATGTCGGTACACGGAGAGGTATCCTTTTTTTGTCCCCCGCCCCCTTCTCAATG
TTTCTAGCTAGCTTTGGGGGTCATTTTGTCATCAGAGCATTCTGTGCCCAGGGACAGGACAGATCTCGAGGACACCACAGTCCACCTGTT
CCCGTCAACAGACGTTAGGTCTCATTTTCCTCCTCATGCAGTGTTGTAGTGTGGGTTGTCAACTTTTCTTTAACTGGCTACGCCACAGCT
GGACACACATGCAGCCCCTGGAGGGCAGCCTCTTCCTGTGCCTCGATGGGGTGGGTGGGAGGGCATCTTCTGTGCGTTGGGTCAGTTTCT
GTTACGTAACGAAAAGGATAAACATCTCCCACGGGAGAGGCCACAGATGGCCACTTCCAGAGCTTGCCCATTGCCTGTCTCTCGCCAATT
CCGTTTATCCAAAAAGGTACATGTTTTTGTATTAAAAAGTAAACAGGGATCAGTGACTGTATTCCAAATAAATATGAATCCCTAAGGGCC
GTGGACAAATTGCCTAACCCAGGGCCAGCGGTATTGCTGAAGGAAAGGGGCAGCTCTCTGGGAAGTGGGCCCTCAGAGATTACTCTGGCT
TTGACCCTTGTTTAGCTGATGGTCATTTCTGGGATTGGAATATTTAATAAGCCCAATTCTAAGTTGATAGGTAATTTTAAATATTCAAAC
CAAATCTTCCCAACAGTTGGCAAGTTGTTTATTTTATATTATTTCTTCCAGGACCTACTTGCTCAGATCTCCAAGCAAGCATTTCTTTTC
TTTTAGGGATGTCTGAAAGTCACATCCAGTTACATTACTGTGTTCTTTCTAATGAAAAGTAAAGGTTTTATATAGAGAAACTTGAGTAAT
TTTTACATTTCTAAGACATTAAATCCCATTTAAATTCTGTGTGAACATTAAAGACAGCACACTTGCAAAAGTATGGTCAAAGGAAAAAAA
TCCCACATTTCAATTAACAAGTAGCATGGACATTTGATCAACCTTTAGTTGGAATAATAATATTCATATTTGCTATGAATCCTTTTAAAA
AAATCTTTGGATAAATGCTGACAGATTTCCAAGAACTACCAAGAAAATACAAGAGATATCCAATGCTTGATATATGAGGCCTAGTAATAA
CGATATTTCTCTTTAATTGATGTTTTGTTTTAAAAGTTAAAAGTAATTCTTGGCGTGGTGGTTCACGCCTGTAATCCCAGCACTTTGGGA
GGCCGAAGCGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCGTCCCTACTAAAAATACAAAATT
AGCCAGGTATGGTGGTGCATACCTGTAATCCCAGCTACTCGGGAACCTGAGGCAGGAGAATGGCTTGAACCCAGGAGACAGAGGTTGTGG
TGGGGCAAGATCGCACCATTGCACCCGAGCCTAGGCAACAAGAGTGAAATTCCGTCTCAAAAAAATAAATAAATAAATAAATAAATAAGT
TAAAATTAATTCTTTATCCAGAGTCGGGTGCTTTAGAATTTATAAGTCACTTATGTGTTTTGCTTGAATTAATTCTGACAGCCCCTATGA
GGAAATCTGGAGGCAGGTAACAGTTCCCATTTTAGAGATGAAGAACTGAGGCACAGATTAAAGGACTTGCCTGTGTTGAATACCAGTCCT
GTTCTAGGACATTCTCCCCTCTCCTAGGAGACGGATGTCACGCACAAATGGGGAGAGAAGTGTTTATTTTGTAGGCACTAAGGGTTTCTA
AAACCCTTAACACTGGTAAGGGCTCAAAAATAAACGTATGTGTTCATATTCGATCACCGAAATGAGAGTTCTTAATTGCTAATTGACAAA
CGCGTTAGCAATTTCAGTTAGGGAGTCATCTCCCTTGATTGTGTTCTTTTCCTGTCAATTTTCATAGACCTAATTTGCAAACTCAATCGG
GGACTAAAATTTCCCACTGAAAATGTTAAACATTTTAGATAACTGTGAAGATAGTTTATTTTTATTCCTTGCCAATCTGGGAATATGCCT
TTTTTGTGTGTTTGTGTGTTTTTTTAAGTGCTGTATTAATAATACTTTCTGAAAGAAAAGGACACTTACCCCAAAACTTCAATCTGAAAT
GTCTTACATTAAGAATATCTTGAATGTTGTGTATATATTTTAAAAAGCACTTTGCAAAATAGTTTGTACATTTATTTCCTAATTTATACA
TGATTTTTGGTGTTAATATATTTAATGATTAATAACAGAATGTTTATTTAATGTGCTGTCCATTTTTATGTAATATTATGGGGAAAGTGA
TGCCAGCAGTTCCTTTTCATTATTCTATCTTCTGTCATATGAATGTTGAGCAAAGCTTAGGCCAACATGAATTGTTTGTGAAGTGTGGTT
GATGGTGCTTTGTTTTTTTCTGACTACTTCTATGGAAGGCCAGTGAAGAAGCAAAGGAAGACATGAAAATTGACGCTCATTCTTCTTCCT
ATTGTTCCCTGACATCCAGCAAATTGTGAATTTGAAAAATGATGGCCAGTTTTCAGAAGTGCTGACAAATTCATATTGGTATGCAAAAGC
TCATCACCCATTAAGGTTTGTTGTTGAATCAACAGTACTCAGCATATTAAAACAGTACATCAGAACTCATGCCAACAGTCTTTATGATGG
GATTAAGGTGGACAAGATCTCCTAAGATCTGTGAATGGGATTAAGGTGGACAAGATCTCCTAAGATCTGAAAAGAAACCTTAATACGCTC
ATATGGTTGGAGTGTTAAGTGAACCTCTGATTTTGTCAGGGTTTTTCTACGTGTAGGCGTGAATAGGGGGCACCCCTTCAAAACTGTACA
AAGAAGACGACTGTTTTCCATTTCCATTTAAACATTTTTAGCCACTTCATTTCTATTTATTGAACAGGTCAAATTTGTCTTGTTATTTGT
GAGTACAGTACATTTAAAAAACATCCTTATCGGTTATTTTTTTTTCAGTCGGAGTTTGACGTATAAATTGTTTATGCTTTTGGTGTAATC

>In-frame_GRB2_ENST00000316615_chr17_73389632_-_SS18L1_ENST00000370848_chr20_60747738_+_3168nt
AAGTTCTCGCGGGACACCGACGGGGAGCGGAAGCCAGGAGGTATTGCTGCTTCGGCGACCGGGCGGCGGCAGCGGCGGCGGCGGCTGTGG
CAGAGTCTGTGCCTGTGGCGGTGACGGCGGCGGGAGCAAGCGCTGCCCTCGCAGAGCAGCCTTGGGGTCGCCGGCCGCTCGCAGCGTTGT
GGAGGGGCGGGCCGGACGCTGAGCGGAGCAGCTGCGCCACGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGC
GAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAAT
GGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGAAACTCCCAGTAC
AGCCAGCAGCAGGCCGGGTACCAGCAGGGTGCCGCGCAGCAGCAGACGTACTCCCAGCAGCAGTACCCCAGCCAGCAGAGCTACCCCGGG
CAGCAGCAGGGCTACGGGTCTGCCCAGGGAGCCCCGTCACAGTACCCCGGCTACCAGCAAGGCCAAGGCCAGCAGTACGGAAGCTACCGA
GCACCGCAGACAGCGCCGTCTGCCCAGCAGCAGCGGCCCTACGGCTATGAACAGGGCCAGTATGGAAATTACCAGCAGTAAGGGACACAC
ATTCTGGCTGGAGCCCTTGTGGTAGCGTGTTCATCCAGGGGCCGGATGGGCTGGCGGCAGCTCTGGTGAATTGTGACATGTTGGTTACCT
GTTCGCCCAGTGCCACGTCTGCATGTGAAGCGTGCTCATTTCATGCTGGGACCTACTTGCTCAGATCTCCAAGCAAGCATTTCTTTTCTT
TTAGGGATGTCTGAAAGTCACATCCAGTTACATTACTGTGTTCTTTCTAATGAAAAGTAAAGGTTTTATATAGAGAAACTTGAGTAATTT
TTACATTTCTAAGACATTAAATCCCATTTAAATTCTGTGTGAACATTAAAGACAGCACACTTGCAAAAGTATGGTCAAAGGAAAAAAATC
CCACATTTCAATTAACAAGTAGCATGGACATTTGATCAACCTTTAGTTGGAATAATAATATTCATATTTGCTATGAATCCTTTTAAAAAA
ATCTTTGGATAAATGCTGACAGATTTCCAAGAACTACCAAGAAAATACAAGAGATATCCAATGCTTGATATATGAGGCCTAGTAATAACG
ATATTTCTCTTTAATTGATGTTTTGTTTTAAAAGTTAAAAGTAATTCTTGGCGTGGTGGTTCACGCCTGTAATCCCAGCACTTTGGGAGG
CCGAAGCGGGCGGATCACCTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACCCCGTCCCTACTAAAAATACAAAATTAG
CCAGGTATGGTGGTGCATACCTGTAATCCCAGCTACTCGGGAACCTGAGGCAGGAGAATGGCTTGAACCCAGGAGACAGAGGTTGTGGTG
GGGCAAGATCGCACCATTGCACCCGAGCCTAGGCAACAAGAGTGAAATTCCGTCTCAAAAAAATAAATAAATAAATAAATAAATAAGTTA
AAATTAATTCTTTATCCAGAGTCGGGTGCTTTAGAATTTATAAGTCACTTATGTGTTTTGCTTGAATTAATTCTGACAGCCCCTATGAGG
AAATCTGGAGGCAGGTAACAGTTCCCATTTTAGAGATGAAGAACTGAGGCACAGATTAAAGGACTTGCCTGTGTTGAATACCAGTCCTGT
TCTAGGACATTCTCCCCTCTCCTAGGAGACGGATGTCACGCACAAATGGGGAGAGAAGTGTTTATTTTGTAGGCACTAAGGGTTTCTAAA
ACCCTTAACACTGGTAAGGGCTCAAAAATAAACGTATGTGTTCATATTCGATCACCGAAATGAGAGTTCTTAATTGCTAATTGACAAACG
CGTTAGCAATTTCAGTTAGGGAGTCATCTCCCTTGATTGTGTTCTTTTCCTGTCAATTTTCATAGACCTAATTTGCAAACTCAATCGGGG
ACTAAAATTTCCCACTGAAAATGTTAAACATTTTAGATAACTGTGAAGATAGTTTATTTTTATTCCTTGCCAATCTGGGAATATGCCTTT
TTTGTGTGTTTGTGTGTTTTTTTAAGTGCTGTATTAATAATACTTTCTGAAAGAAAAGGACACTTACCCCAAAACTTCAATCTGAAATGT
CTTACATTAAGAATATCTTGAATGTTGTGTATATATTTTAAAAAGCACTTTGCAAAATAGTTTGTACATTTATTTCCTAATTTATACATG
ATTTTTGGTGTTAATATATTTAATGATTAATAACAGAATGTTTATTTAATGTGCTGTCCATTTTTATGTAATATTATGGGGAAAGTGATG
CCAGCAGTTCCTTTTCATTATTCTATCTTCTGTCATATGAATGTTGAGCAAAGCTTAGGCCAACATGAATTGTTTGTGAAGTGTGGTTGA
TGGTGCTTTGTTTTTTTCTGACTACTTCTATGGAAGGCCAGTGAAGAAGCAAAGGAAGACATGAAAATTGACGCTCATTCTTCTTCCTAT
TGTTCCCTGACATCCAGCAAATTGTGAATTTGAAAAATGATGGCCAGTTTTCAGAAGTGCTGACAAATTCATATTGGTATGCAAAAGCTC
ATCACCCATTAAGGTTTGTTGTTGAATCAACAGTACTCAGCATATTAAAACAGTACATCAGAACTCATGCCAACAGTCTTTATGATGGGA
TTAAGGTGGACAAGATCTCCTAAGATCTGTGAATGGGATTAAGGTGGACAAGATCTCCTAAGATCTGAAAAGAAACCTTAATACGCTCAT
ATGGTTGGAGTGTTAAGTGAACCTCTGATTTTGTCAGGGTTTTTCTACGTGTAGGCGTGAATAGGGGGCACCCCTTCAAAACTGTACAAA
GAAGACGACTGTTTTCCATTTCCATTTAAACATTTTTAGCCACTTCATTTCTATTTATTGAACAGGTCAAATTTGTCTTGTTATTTGTGA
GTACAGTACATTTAAAAAACATCCTTATCGGTTATTTTTTTTTCAGTCGGAGTTTGACGTATAAATTGTTTATGCTTTTGGTGTAATCTC


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FusionGenePPI for GRB2_SS18L1


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check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
GRB2CSF1R, PRRC2A, EGFR, ERBB2, ERBB3, ERBB4, MED28, BCR, GAB2, CBL, ETV6, LY6G6F, NEU3, SRC, PDE6G, DOCK1, FASLG, SHC1, SOS1, VAV2, VAV3, RACGAP1, IQGAP1, KRT7, KRT8, KRT17, KRT18, PLEC, EPPK1, BCAR1, WAS, MAP4K1, BLNK, IL2RB, SYN1, PDGFRB, KHDRBS1, PTPN6, PTPN11, SYK, CD22, GAB1, IRS1, TNFRSF1A, PTK2, SH3BP2, CD28, TNK2, KIT, SOCS1, PTPRA, CBLB, EPHA2, AXL, DAG1, MAP2, PLCG1, MST1R, ITGA2B, NCKIPSD, NTRK1, PTPN1, JAK2, GRB2, USP8, CSF3R, HTT, MET, LCP2, SNTA1, ABL1, LAT, FLT4, PIK3R1, FRS2, GAB3, VAV1, SH2B2, SH2B1, PRKAR1A, DCTN1, RET, CRK, PTPN22, JAK1, ARHGAP17, SHB, REPS2, OCRL, PDGFRA, PXN, PAG1, TRAT1, INSR, RAPGEF1, KDR, SELL, ADRB2, EPOR, SYNCRIP, ZAP70, IRS4, MUC1, ITK, LAT2, SH2B3, ANXA2, ARHGAP35, RASA1, PTPN12, CRKL, ADAM15, ADAM10, WASL, EPS15, IL6ST, SH3KBP1, EPHB1, MAP3K1, FLT3, RALGPS1, USP6NL, SPRY2, PTPRE, DNM1, HNRNPC, MAPK9, DRD3, CDKN1B, ALOX5, PIK3C2B, GHR, HCLS1, DTX1, LAX1, SOS2, DRD4, PTK2B, SKAP1, TOM1L1, SHKBP1, FGFR3, INPP5D, MICAL1, PLXNB1, OTUD5, STAMBP, ALK, NPM1, BTK, CSN2, DAB2, EP300, HNRNPK, HSPA5, MAP1A, ATP8, ND4, MYH9, MYH11, NCL, NFYB, PIK3R2, RBBP6, SLC1A2, SPTBN1, SS18, UBA52, UBC, WIPF1, MAP4K3, ASAP2, SYNJ2, DLGAP1, ARHGAP32, HELZ, PDCD6IP, HIPK3, DCTN2, TCERG1, KIF3A, MAP4K5, KIAA1549L, ABI3BP, PTPN23, ASAP1, ERRFI1, WDR44, USP53, RIF1, SH2D4A, GAREM, RBM33, MSI2, WIPF2, SH3D19, NAP1L5, STK32C, MYO18A, A2M, AEBP1, AGT, AHSG, ALAS2, STRADB, AMBP, APCS, APOH, SNRNP200, B2M, GPANK1, BPGM, CLU, DNAJA3, DNAJB11, ESD, FABP1, FHOD1, FN1, GC, H1F0, HP, IK, PBXIP1, POLR2A, PRKAB1, RNF10, TF, TFG, TSC2, ENO1, ITIH4, AP4S1, CUTA, POMP, C21orf58, CD164, C21orf91, CFH, COX6A1, ECHS1, FH, NADK, FTL, PRAP1, GSTK1, TCEAL8, POLR1D, RBP4, SHBG, WDR1, IRF5, PPP3CA, GIT1, CDC42, CASP2, ELAVL1, SYNM, AP2A2, DNM2, NCK1, UBASH3B, CUL3, DCUN1D1, LRRK1, INPPL1, ARAP1, KRT85, HSPA8, HSPG2, KRT86, KRT1, KRT81, KRT35, CAD, KRT10, KRT2, HSPA9, KRT83, CCT8, KRT9, KRT33B, HSP90AA1, DNM3, DYNC1H1, TUBB, KRT34, RPS19, HSPA1B, HSP90AB1, SKAP2, CCT4, EEF1A1P5, KRT6A, KRT14, TUBB4B, TUBA1C, KRT16, TCP1, CCT2, ACTB, FAM175B, CCT3, KRT5, KRT15, CLPX, EEF1G, PSMD11, CALM3, HSPA1L, KRT32, DARS, HSPD1, EEF1D, CNOT1, UBR4, AHNAK, CLTC, KRT36, KRT82, MFAP4, PSTPIP2, PSMC2, PSME1, PSMD14, CD2AP, FUS, BRE, KRT19, CTTN, KRT4, VASP, CCT7, KRT73, HNRNPU, BABAM1, HNRNPD, DRG1, IMPDH2, SERBP1, PIK3CA, TUBA4B, BRCC3, DOK3, HIST4H4, GAPDH, RUVBL1, PSMD13, RPS20, ACTL6A, RARS, CCT5, HSD17B4, TSG101, IRS2, PDE4D, SPRY1, SPRY4, VCAM1, ELMO2, WDR6, WDR77, SNX18, NISCH, YWHAZ, STARD10, YWHAE, SH3PXD2B, DOCK4, PEAK1, PIK3CB, SLC25A5, YWHAB, YWHAQ, PPP2R2A, SIRPA, SYNJ1, FGD6, PIK3AP1, KIRREL, YWHAG, GAREML, AGER, WIPF3, PTPN18, SLC25A13, CYFIP2, ARHGEF7, PPP1CA, CSK, PTPRJ, YWHAH, CSRP1, SH3PXD2A, TTYH2, PIK3R3, FLNA, ARHGAP12, RADIL, SH2D5, FAU, NCKAP1, DIAPH1, HGS, CLASP2, TEC, SLC25A6, HUNK, MLLT4, C1orf27, PPP1CC, HDGFRP3, SLAIN2, EPS15L1, IGF2BP1, PPP5C, GJA9, TAB1, ITGA4, BAG3, CKS2, FTH1, COPB1, PHACTR4, SF3B4, VIM, UBA1, PHC2, KPNA2, CTAGE5, PON2, ARHGEF5, CASC3, MLXIPL, WBP11, YLPM1, SHANK3, NKD2, SLX1A, ACTG1, CBR1, AP2A1, AP2B1, AP2M1, AP2S1, HIST1H3A, SMU1, SNRPD2, CD59, ABL2, AES, EPS8, LMO2, REL, TRIM27, TP53BP2, DDX17, IKZF3, ZBTB7B, ABI3, NUTM2F, DPPA4, HOMEZ, NIF3L1, ARHGAP9, LZTS2, LNX1, C1orf94, PNMA5, PRR22, INCA1, DOK1, FKBP2, FABP5, ITCH, ROS1, HEXB, ACAP1, PLEKHS1, AUNIP, UQCC2, CRBN, LMX1A, MYOZ1, PACRGL, PARD6A, PCDHB5, PPARA, RB1, SOCS4, TMEM128, TSPAN2, VCP, WDFY3, DBN1, E2F2, ARL6IP4, OLIG1, WBSCR27, ZMAT1, CLNK, CEP170, FBF1, MCM2, USP12, GFAP, NEFH, HNRNPA2B1, RPS27A, LGALS3BP, MYL12A, MYL12B, S100A8, S100A9, ESRRB, LIME1, KRAS, LTK, SHC2, SHC4, DUSP13, DUSP8, CYLD, VPS37B, NKX2-5, SPATA2L, MVB12A, ZMYM6, VPS28, DOCK5, THEMIS, RAC1, TRIM25SS18L1SF3B4, RFX6, CREBBP, EP300, USP30, SMARCA4, ATF3, ELF5, HDAC2, SMAD1, SMAD3, STAT3, TCF7, HDAC4, NR1H3, BRD1, AATF, RLIM, TAF9B, GATAD1, PCGF6, MED30, ANKRD22, WHSC1L1, SKA3, CUL3, DGCR6, CSTF2, LGALS3, CTAGE5, SNRPB, SNRPC, FAM168A, SS18L1, MAPK1IP1L, BMI1, DPF3, DPF2, SMARCE1, SMARCD1, SMARCC1, SMARCC2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for GRB2_SS18L1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GRB2_SS18L1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneGRB2C0036341Schizophrenia2PSYGENET