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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 15366

FusionGeneSummary for GRB2_SLC25A19

check button Fusion gene summary
Fusion gene informationFusion gene name: GRB2_SLC25A19
Fusion gene ID: 15366
HgeneTgene
Gene symbol

GRB2

SLC25A19

Gene ID

2885

60386

Gene namegrowth factor receptor bound protein 2solute carrier family 25 member 19
SynonymsASH|EGFRBP-GRB2|Grb3-3|MST084|MSTP084|NCKAP2DNC|MCPHA|MUP1|THMD3|THMD4|TPC
Cytomap

17q25.1

17q25.1

Type of geneprotein-codingprotein-coding
Descriptiongrowth factor receptor-bound protein 2HT027SH2/SH3 adapter GRB2abundant SRC homologyepidermal growth factor receptor-binding protein GRB2growth factor receptor-bound protein 3protein Ashmitochondrial thiamine pyrophosphate carriermitochondrial uncoupling protein 1solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
Modification date2018052720180523
UniProtAcc

P62993

Q9HC21

Ensembl transtripts involved in fusion geneENST00000392562, ENST00000316804, 
ENST00000316615, ENST00000392563, 
ENST00000392564, ENST00000578961, 
ENST00000462266, 
ENST00000416858, 
ENST00000402418, ENST00000442286, 
ENST00000320362, ENST00000580994, 
ENST00000375261, 
Fusion gene scores* DoF score11 X 4 X 9=3961 X 1 X 1=1
# samples 111
** MAII scorelog2(11/396*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(1/1*10)=3.32192809488736
Context

PubMed: GRB2 [Title/Abstract] AND SLC25A19 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDLUADTCGA-86-6851-01AGRB2chr17

73389632

-SLC25A19chr17

73279674

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shitENST00000392562ENST00000416858GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000392562ENST00000402418GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000392562ENST00000442286GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000392562ENST00000320362GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000392562ENST00000580994GRB2chr17

73389632

-SLC25A19chr17

73279674

-
5CDS-intronENST00000392562ENST00000375261GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000316804ENST00000416858GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000316804ENST00000402418GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000316804ENST00000442286GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000316804ENST00000320362GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000316804ENST00000580994GRB2chr17

73389632

-SLC25A19chr17

73279674

-
5CDS-intronENST00000316804ENST00000375261GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000316615ENST00000416858GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000316615ENST00000402418GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000316615ENST00000442286GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000316615ENST00000320362GRB2chr17

73389632

-SLC25A19chr17

73279674

-
Frame-shitENST00000316615ENST00000580994GRB2chr17

73389632

-SLC25A19chr17

73279674

-
5CDS-intronENST00000316615ENST00000375261GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000392563ENST00000416858GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000392563ENST00000402418GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000392563ENST00000442286GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000392563ENST00000320362GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000392563ENST00000580994GRB2chr17

73389632

-SLC25A19chr17

73279674

-
5CDS-intronENST00000392563ENST00000375261GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000392564ENST00000416858GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000392564ENST00000402418GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000392564ENST00000442286GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000392564ENST00000320362GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000392564ENST00000580994GRB2chr17

73389632

-SLC25A19chr17

73279674

-
5CDS-intronENST00000392564ENST00000375261GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000578961ENST00000416858GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000578961ENST00000402418GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000578961ENST00000442286GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000578961ENST00000320362GRB2chr17

73389632

-SLC25A19chr17

73279674

-
In-frameENST00000578961ENST00000580994GRB2chr17

73389632

-SLC25A19chr17

73279674

-
5CDS-intronENST00000578961ENST00000375261GRB2chr17

73389632

-SLC25A19chr17

73279674

-
intron-3CDSENST00000462266ENST00000416858GRB2chr17

73389632

-SLC25A19chr17

73279674

-
intron-3CDSENST00000462266ENST00000402418GRB2chr17

73389632

-SLC25A19chr17

73279674

-
intron-3CDSENST00000462266ENST00000442286GRB2chr17

73389632

-SLC25A19chr17

73279674

-
intron-3CDSENST00000462266ENST00000320362GRB2chr17

73389632

-SLC25A19chr17

73279674

-
intron-3CDSENST00000462266ENST00000580994GRB2chr17

73389632

-SLC25A19chr17

73279674

-
intron-intronENST00000462266ENST00000375261GRB2chr17

73389632

-SLC25A19chr17

73279674

-

Top

FusionProtFeatures for GRB2_SLC25A19


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GRB2

P62993

SLC25A19

Q9HC21

Adapter protein that provides a critical link betweencell surface growth factor receptors and the Ras signalingpathway. Isoform 2 does not bind to phosphorylated epidermalgrowth factor receptor (EGFR) but inhibits EGF-inducedtransactivation of a RAS-responsive element. Isoform 2 acts as adominant negative protein over GRB2 and by suppressingproliferative signals, may trigger active programmed cell death. Mitochondrial transporter mediating uptake of thiaminepyrophosphate (ThPP) into mitochondria.{ECO:0000269|PubMed:18280798}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for GRB2_SLC25A19


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000416858_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000402418_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000442286_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000320362_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000580994_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000416858_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000402418_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000442286_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000320362_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000580994_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000416858_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000402418_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000442286_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000320362_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000580994_chr17_73279674_-_251aa
MEAIAKTDFKATADDELSFKRGDILKFLSFEMLTELVHRGSVTDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVTNTLRH
AVGTMTRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTTPLDLFKKRLQVGGFE


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000416858_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000402418_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000442286_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000320362_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000580994_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000416858_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000402418_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000442286_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000320362_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000580994_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000416858_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000402418_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000442286_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000320362_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000580994_chr17_73279674_-_753nt
ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTT
GAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGT
ATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCAC
GCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGG
CTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTG
CTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAG
CATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGC
TTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTC


* Fusion transcript sequences (Full-length transcript).
>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000416858_chr17_73279674_-_1240nt
GGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAG
GGGGGACATCCTCAAGTTCTTGTCATTTGAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCA
CTTTGTATGTGGTGGCCTGGCTGCCTGTATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGA
GCCCAAGGTCTATAATACGCTGCGCCACGCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCAC
CTTGATCGCCATCTTCCCCTACGCCGGGCTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGG
AAAGAAAAATGAGAACCTCCAAAACCTGCTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAA
GAAGCGGCTACAGGTTGGAGGGTTTGAGCATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCA
GGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTT
CTCGTATGAATTCTTCTGTAATGTCTTCCACTGCATGAACAGGACAGCCAGCCAGCGCTGAGTGCAGGAAGGACCCCAGGTCTTCCCTGG
AGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCTCCACTGAGAGGTGCCGTCTGGCCCTTCCCTGCAGGCCAGCTGCCCCAAGCGGGGTAG
CAGCCTTGAACCCACCCAGCTGGGACACCACCAGAAGGTCCAGGGCTCTCCCCATGAGAGAATCAGAGGGAATGCAGGACGTGGTCTATG
GTGAGCCAACGACACAGTGAGAAGGAGCAGGAAGTTGCTGTTTCTCCTCTGACCAGCCCACACTCCAAAGGAAACAGACGCCATCCTACA
CCTATCAGCCCTGCCTGCCAGGAGAACAGAACACACTCCTGGTCTGGATGGGGCTGCTGCTTGAGTGCAGAGGGCTGCGGTAGGCCCTTT

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000402418_chr17_73279674_-_1239nt
GGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAG
GGGGGACATCCTCAAGTTCTTGTCATTTGAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCA
CTTTGTATGTGGTGGCCTGGCTGCCTGTATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGA
GCCCAAGGTCTATAATACGCTGCGCCACGCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCAC
CTTGATCGCCATCTTCCCCTACGCCGGGCTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGG
AAAGAAAAATGAGAACCTCCAAAACCTGCTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAA
GAAGCGGCTACAGGTTGGAGGGTTTGAGCATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCA
GGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTT
CTCGTATGAATTCTTCTGTAATGTCTTCCACTGCATGAACAGGACAGCCAGCCAGCGCTGAGTGCAGGAAGGACCCCAGGTCTTCCCTGG
AGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCTCCACTGAGAGGTGCCGTCTGGCCCTTCCCTGCAGGCCAGCTGCCCCAAGCGGGGTAG
CAGCCTTGAACCCACCCAGCTGGGACACCACCAGAAGGTCCAGGGCTCTCCCCATGAGAGAATCAGAGGGAATGCAGGACGTGGTCTATG
GTGAGCCAACGACACAGTGAGAAGGAGCAGGAAGTTGCTGTTTCTCCTCTGACCAGCCCACACTCCAAAGGAAACAGACGCCATCCTACA
CCTATCAGCCCTGCCTGCCAGGAGAACAGAACACACTCCTGGTCTGGATGGGGCTGCTGCTTGAGTGCAGAGGGCTGCGGTAGGCCCTTT

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000442286_chr17_73279674_-_1239nt
GGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAG
GGGGGACATCCTCAAGTTCTTGTCATTTGAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCA
CTTTGTATGTGGTGGCCTGGCTGCCTGTATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGA
GCCCAAGGTCTATAATACGCTGCGCCACGCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCAC
CTTGATCGCCATCTTCCCCTACGCCGGGCTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGG
AAAGAAAAATGAGAACCTCCAAAACCTGCTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAA
GAAGCGGCTACAGGTTGGAGGGTTTGAGCATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCA
GGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTT
CTCGTATGAATTCTTCTGTAATGTCTTCCACTGCATGAACAGGACAGCCAGCCAGCGCTGAGTGCAGGAAGGACCCCAGGTCTTCCCTGG
AGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCTCCACTGAGAGGTGCCGTCTGGCCCTTCCCTGCAGGCCAGCTGCCCCAAGCGGGGTAG
CAGCCTTGAACCCACCCAGCTGGGACACCACCAGAAGGTCCAGGGCTCTCCCCATGAGAGAATCAGAGGGAATGCAGGACGTGGTCTATG
GTGAGCCAACGACACAGTGAGAAGGAGCAGGAAGTTGCTGTTTCTCCTCTGACCAGCCCACACTCCAAAGGAAACAGACGCCATCCTACA
CCTATCAGCCCTGCCTGCCAGGAGAACAGAACACACTCCTGGTCTGGATGGGGCTGCTGCTTGAGTGCAGAGGGCTGCGGTAGGCCCTTT

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000320362_chr17_73279674_-_1239nt
GGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAG
GGGGGACATCCTCAAGTTCTTGTCATTTGAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCA
CTTTGTATGTGGTGGCCTGGCTGCCTGTATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGA
GCCCAAGGTCTATAATACGCTGCGCCACGCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCAC
CTTGATCGCCATCTTCCCCTACGCCGGGCTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGG
AAAGAAAAATGAGAACCTCCAAAACCTGCTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAA
GAAGCGGCTACAGGTTGGAGGGTTTGAGCATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCA
GGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTT
CTCGTATGAATTCTTCTGTAATGTCTTCCACTGCATGAACAGGACAGCCAGCCAGCGCTGAGTGCAGGAAGGACCCCAGGTCTTCCCTGG
AGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCTCCACTGAGAGGTGCCGTCTGGCCCTTCCCTGCAGGCCAGCTGCCCCAAGCGGGGTAG
CAGCCTTGAACCCACCCAGCTGGGACACCACCAGAAGGTCCAGGGCTCTCCCCATGAGAGAATCAGAGGGAATGCAGGACGTGGTCTATG
GTGAGCCAACGACACAGTGAGAAGGAGCAGGAAGTTGCTGTTTCTCCTCTGACCAGCCCACACTCCAAAGGAAACAGACGCCATCCTACA
CCTATCAGCCCTGCCTGCCAGGAGAACAGAACACACTCCTGGTCTGGATGGGGCTGCTGCTTGAGTGCAGAGGGCTGCGGTAGGCCCTTT

>In-frame_GRB2_ENST00000392563_chr17_73389632_-_SLC25A19_ENST00000580994_chr17_73279674_-_1202nt
GGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAG
GGGGGACATCCTCAAGTTCTTGTCATTTGAAATGCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCA
CTTTGTATGTGGTGGCCTGGCTGCCTGTATGGCCACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGA
GCCCAAGGTCTATAATACGCTGCGCCACGCCGTGGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCAC
CTTGATCGCCATCTTCCCCTACGCCGGGCTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGG
AAAGAAAAATGAGAACCTCCAAAACCTGCTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAA
GAAGCGGCTACAGGTTGGAGGGTTTGAGCATGCCAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCA
GGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTT
CTCGTATGAATTCTTCTGTAATGTCTTCCACTGCATGAACAGGACAGCCAGCCAGCGCTGAGTGCAGGAAGGACCCCAGGTCTTCCCTGG
AGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCTCCACTGAGAGGTGCCGTCTGGCCCTTCCCTGCAGGCCAGCTGCCCCAAGCGGGGTAG
CAGCCTTGAACCCACCCAGCTGGGACACCACCAGAAGGTCCAGGGCTCTCCCCATGAGAGAATCAGAGGGAATGCAGGACGTGGTCTATG
GTGAGCCAACGACACAGTGAGAAGGAGCAGGAAGTTGCTGTTTCTCCTCTGACCAGCCCACACTCCAAAGGAAACAGACGCCATCCTACA
CCTATCAGCCCTGCCTGCCAGGAGAACAGAACACACTCCTGGTCTGGATGGGGCTGCTGCTTGAGTGCAGAGGGCTGCGGTAGGCCCTTT

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000416858_chr17_73279674_-_1448nt
GAGCCAGGGGGCGTGGGGGCTGGGACAGCAGGCCGATTGGCAGGGCGGGGTTGCCTTCAATCCTGGCCACTGCTCTTAATCGTCCCTCTC
CTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAG
CAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTA
CTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTTGAAATGCTGACGGAGCTGGTCCACAGAGGCAGCG
TGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGTATGGCCACCCTCACTGTGCACCCCGTGGATGTTC
TGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCACGCCGTGGGGACCATGTATAGGAGCGAAGGCCCCC
AGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGGCTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACC
TGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTGCTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGA
CCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAGCATGCCAGAGCTGCCTTTGGCCAGGTACGGAGAT
ACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGG
CTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTCCACTGCATGAACAGGACAGCCAGCCAGCGCTGAG
TGCAGGAAGGACCCCAGGTCTTCCCTGGAGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCTCCACTGAGAGGTGCCGTCTGGCCCTTCCC
TGCAGGCCAGCTGCCCCAAGCGGGGTAGCAGCCTTGAACCCACCCAGCTGGGACACCACCAGAAGGTCCAGGGCTCTCCCCATGAGAGAA
TCAGAGGGAATGCAGGACGTGGTCTATGGTGAGCCAACGACACAGTGAGAAGGAGCAGGAAGTTGCTGTTTCTCCTCTGACCAGCCCACA
CTCCAAAGGAAACAGACGCCATCCTACACCTATCAGCCCTGCCTGCCAGGAGAACAGAACACACTCCTGGTCTGGATGGGGCTGCTGCTT
GAGTGCAGAGGGCTGCGGTAGGCCCTTTGCAGGAGTCAGGTCCCTACACTTGGCCTGTTTTTCCAACCTATTTAATAGACATTAAAGCTA

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000402418_chr17_73279674_-_1447nt
GAGCCAGGGGGCGTGGGGGCTGGGACAGCAGGCCGATTGGCAGGGCGGGGTTGCCTTCAATCCTGGCCACTGCTCTTAATCGTCCCTCTC
CTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAG
CAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTA
CTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTTGAAATGCTGACGGAGCTGGTCCACAGAGGCAGCG
TGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGTATGGCCACCCTCACTGTGCACCCCGTGGATGTTC
TGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCACGCCGTGGGGACCATGTATAGGAGCGAAGGCCCCC
AGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGGCTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACC
TGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTGCTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGA
CCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAGCATGCCAGAGCTGCCTTTGGCCAGGTACGGAGAT
ACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGG
CTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTCCACTGCATGAACAGGACAGCCAGCCAGCGCTGAG
TGCAGGAAGGACCCCAGGTCTTCCCTGGAGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCTCCACTGAGAGGTGCCGTCTGGCCCTTCCC
TGCAGGCCAGCTGCCCCAAGCGGGGTAGCAGCCTTGAACCCACCCAGCTGGGACACCACCAGAAGGTCCAGGGCTCTCCCCATGAGAGAA
TCAGAGGGAATGCAGGACGTGGTCTATGGTGAGCCAACGACACAGTGAGAAGGAGCAGGAAGTTGCTGTTTCTCCTCTGACCAGCCCACA
CTCCAAAGGAAACAGACGCCATCCTACACCTATCAGCCCTGCCTGCCAGGAGAACAGAACACACTCCTGGTCTGGATGGGGCTGCTGCTT
GAGTGCAGAGGGCTGCGGTAGGCCCTTTGCAGGAGTCAGGTCCCTACACTTGGCCTGTTTTTCCAACCTATTTAATAGACATTAAAGCTA

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000442286_chr17_73279674_-_1447nt
GAGCCAGGGGGCGTGGGGGCTGGGACAGCAGGCCGATTGGCAGGGCGGGGTTGCCTTCAATCCTGGCCACTGCTCTTAATCGTCCCTCTC
CTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAG
CAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTA
CTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTTGAAATGCTGACGGAGCTGGTCCACAGAGGCAGCG
TGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGTATGGCCACCCTCACTGTGCACCCCGTGGATGTTC
TGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCACGCCGTGGGGACCATGTATAGGAGCGAAGGCCCCC
AGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGGCTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACC
TGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTGCTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGA
CCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAGCATGCCAGAGCTGCCTTTGGCCAGGTACGGAGAT
ACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGG
CTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTCCACTGCATGAACAGGACAGCCAGCCAGCGCTGAG
TGCAGGAAGGACCCCAGGTCTTCCCTGGAGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCTCCACTGAGAGGTGCCGTCTGGCCCTTCCC
TGCAGGCCAGCTGCCCCAAGCGGGGTAGCAGCCTTGAACCCACCCAGCTGGGACACCACCAGAAGGTCCAGGGCTCTCCCCATGAGAGAA
TCAGAGGGAATGCAGGACGTGGTCTATGGTGAGCCAACGACACAGTGAGAAGGAGCAGGAAGTTGCTGTTTCTCCTCTGACCAGCCCACA
CTCCAAAGGAAACAGACGCCATCCTACACCTATCAGCCCTGCCTGCCAGGAGAACAGAACACACTCCTGGTCTGGATGGGGCTGCTGCTT
GAGTGCAGAGGGCTGCGGTAGGCCCTTTGCAGGAGTCAGGTCCCTACACTTGGCCTGTTTTTCCAACCTATTTAATAGACATTAAAGCTA

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000320362_chr17_73279674_-_1447nt
GAGCCAGGGGGCGTGGGGGCTGGGACAGCAGGCCGATTGGCAGGGCGGGGTTGCCTTCAATCCTGGCCACTGCTCTTAATCGTCCCTCTC
CTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAG
CAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTA
CTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTTGAAATGCTGACGGAGCTGGTCCACAGAGGCAGCG
TGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGTATGGCCACCCTCACTGTGCACCCCGTGGATGTTC
TGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCACGCCGTGGGGACCATGTATAGGAGCGAAGGCCCCC
AGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGGCTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACC
TGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTGCTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGA
CCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAGCATGCCAGAGCTGCCTTTGGCCAGGTACGGAGAT
ACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGG
CTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTCCACTGCATGAACAGGACAGCCAGCCAGCGCTGAG
TGCAGGAAGGACCCCAGGTCTTCCCTGGAGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCTCCACTGAGAGGTGCCGTCTGGCCCTTCCC
TGCAGGCCAGCTGCCCCAAGCGGGGTAGCAGCCTTGAACCCACCCAGCTGGGACACCACCAGAAGGTCCAGGGCTCTCCCCATGAGAGAA
TCAGAGGGAATGCAGGACGTGGTCTATGGTGAGCCAACGACACAGTGAGAAGGAGCAGGAAGTTGCTGTTTCTCCTCTGACCAGCCCACA
CTCCAAAGGAAACAGACGCCATCCTACACCTATCAGCCCTGCCTGCCAGGAGAACAGAACACACTCCTGGTCTGGATGGGGCTGCTGCTT
GAGTGCAGAGGGCTGCGGTAGGCCCTTTGCAGGAGTCAGGTCCCTACACTTGGCCTGTTTTTCCAACCTATTTAATAGACATTAAAGCTA

>In-frame_GRB2_ENST00000392564_chr17_73389632_-_SLC25A19_ENST00000580994_chr17_73279674_-_1410nt
GAGCCAGGGGGCGTGGGGGCTGGGACAGCAGGCCGATTGGCAGGGCGGGGTTGCCTTCAATCCTGGCCACTGCTCTTAATCGTCCCTCTC
CTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAG
CAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTA
CTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTTGAAATGCTGACGGAGCTGGTCCACAGAGGCAGCG
TGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGTATGGCCACCCTCACTGTGCACCCCGTGGATGTTC
TGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCACGCCGTGGGGACCATGTATAGGAGCGAAGGCCCCC
AGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGGCTGCAGTTCTCTTGCTACAGCTCCTTGAAGCACC
TGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTGCTTTGTGGCAGTGGAGCTGGTGTCATCAGCAAGA
CCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAGCATGCCAGAGCTGCCTTTGGCCAGGTACGGAGAT
ACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTTCAAGGGCCTGTCCCCCAGCTTGCTGAAGG
CTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTCCACTGCATGAACAGGACAGCCAGCCAGCGCTGAG
TGCAGGAAGGACCCCAGGTCTTCCCTGGAGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCTCCACTGAGAGGTGCCGTCTGGCCCTTCCC
TGCAGGCCAGCTGCCCCAAGCGGGGTAGCAGCCTTGAACCCACCCAGCTGGGACACCACCAGAAGGTCCAGGGCTCTCCCCATGAGAGAA
TCAGAGGGAATGCAGGACGTGGTCTATGGTGAGCCAACGACACAGTGAGAAGGAGCAGGAAGTTGCTGTTTCTCCTCTGACCAGCCCACA
CTCCAAAGGAAACAGACGCCATCCTACACCTATCAGCCCTGCCTGCCAGGAGAACAGAACACACTCCTGGTCTGGATGGGGCTGCTGCTT

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000416858_chr17_73279674_-_1387nt
CCTGGCCACTGCTCTTAATCGTCCCTCTCCTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAG
GCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGA
AGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTTGAAAT
GCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGTATGGC
CACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCACGCCGT
GGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGGCTGCA
GTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTGCTTTG
TGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAGCATGC
CAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTT
CAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTCCACTG
CATGAACAGGACAGCCAGCCAGCGCTGAGTGCAGGAAGGACCCCAGGTCTTCCCTGGAGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCT
CCACTGAGAGGTGCCGTCTGGCCCTTCCCTGCAGGCCAGCTGCCCCAAGCGGGGTAGCAGCCTTGAACCCACCCAGCTGGGACACCACCA
GAAGGTCCAGGGCTCTCCCCATGAGAGAATCAGAGGGAATGCAGGACGTGGTCTATGGTGAGCCAACGACACAGTGAGAAGGAGCAGGAA
GTTGCTGTTTCTCCTCTGACCAGCCCACACTCCAAAGGAAACAGACGCCATCCTACACCTATCAGCCCTGCCTGCCAGGAGAACAGAACA
CACTCCTGGTCTGGATGGGGCTGCTGCTTGAGTGCAGAGGGCTGCGGTAGGCCCTTTGCAGGAGTCAGGTCCCTACACTTGGCCTGTTTT

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000402418_chr17_73279674_-_1386nt
CCTGGCCACTGCTCTTAATCGTCCCTCTCCTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAG
GCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGA
AGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTTGAAAT
GCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGTATGGC
CACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCACGCCGT
GGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGGCTGCA
GTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTGCTTTG
TGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAGCATGC
CAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTT
CAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTCCACTG
CATGAACAGGACAGCCAGCCAGCGCTGAGTGCAGGAAGGACCCCAGGTCTTCCCTGGAGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCT
CCACTGAGAGGTGCCGTCTGGCCCTTCCCTGCAGGCCAGCTGCCCCAAGCGGGGTAGCAGCCTTGAACCCACCCAGCTGGGACACCACCA
GAAGGTCCAGGGCTCTCCCCATGAGAGAATCAGAGGGAATGCAGGACGTGGTCTATGGTGAGCCAACGACACAGTGAGAAGGAGCAGGAA
GTTGCTGTTTCTCCTCTGACCAGCCCACACTCCAAAGGAAACAGACGCCATCCTACACCTATCAGCCCTGCCTGCCAGGAGAACAGAACA
CACTCCTGGTCTGGATGGGGCTGCTGCTTGAGTGCAGAGGGCTGCGGTAGGCCCTTTGCAGGAGTCAGGTCCCTACACTTGGCCTGTTTT

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000442286_chr17_73279674_-_1386nt
CCTGGCCACTGCTCTTAATCGTCCCTCTCCTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAG
GCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGA
AGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTTGAAAT
GCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGTATGGC
CACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCACGCCGT
GGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGGCTGCA
GTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTGCTTTG
TGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAGCATGC
CAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTT
CAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTCCACTG
CATGAACAGGACAGCCAGCCAGCGCTGAGTGCAGGAAGGACCCCAGGTCTTCCCTGGAGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCT
CCACTGAGAGGTGCCGTCTGGCCCTTCCCTGCAGGCCAGCTGCCCCAAGCGGGGTAGCAGCCTTGAACCCACCCAGCTGGGACACCACCA
GAAGGTCCAGGGCTCTCCCCATGAGAGAATCAGAGGGAATGCAGGACGTGGTCTATGGTGAGCCAACGACACAGTGAGAAGGAGCAGGAA
GTTGCTGTTTCTCCTCTGACCAGCCCACACTCCAAAGGAAACAGACGCCATCCTACACCTATCAGCCCTGCCTGCCAGGAGAACAGAACA
CACTCCTGGTCTGGATGGGGCTGCTGCTTGAGTGCAGAGGGCTGCGGTAGGCCCTTTGCAGGAGTCAGGTCCCTACACTTGGCCTGTTTT

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000320362_chr17_73279674_-_1386nt
CCTGGCCACTGCTCTTAATCGTCCCTCTCCTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAG
GCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGA
AGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTTGAAAT
GCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGTATGGC
CACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCACGCCGT
GGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGGCTGCA
GTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTGCTTTG
TGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAGCATGC
CAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTT
CAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTCCACTG
CATGAACAGGACAGCCAGCCAGCGCTGAGTGCAGGAAGGACCCCAGGTCTTCCCTGGAGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCT
CCACTGAGAGGTGCCGTCTGGCCCTTCCCTGCAGGCCAGCTGCCCCAAGCGGGGTAGCAGCCTTGAACCCACCCAGCTGGGACACCACCA
GAAGGTCCAGGGCTCTCCCCATGAGAGAATCAGAGGGAATGCAGGACGTGGTCTATGGTGAGCCAACGACACAGTGAGAAGGAGCAGGAA
GTTGCTGTTTCTCCTCTGACCAGCCCACACTCCAAAGGAAACAGACGCCATCCTACACCTATCAGCCCTGCCTGCCAGGAGAACAGAACA
CACTCCTGGTCTGGATGGGGCTGCTGCTTGAGTGCAGAGGGCTGCGGTAGGCCCTTTGCAGGAGTCAGGTCCCTACACTTGGCCTGTTTT

>In-frame_GRB2_ENST00000578961_chr17_73389632_-_SLC25A19_ENST00000580994_chr17_73279674_-_1349nt
CCTGGCCACTGCTCTTAATCGTCCCTCTCCTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAG
GCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGA
AGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGTTCTTGTCATTTGAAAT
GCTGACGGAGCTGGTCCACAGAGGCAGCGTGTATGACGCCCGGGAATTCTCAGTGCACTTTGTATGTGGTGGCCTGGCTGCCTGTATGGC
CACCCTCACTGTGCACCCCGTGGATGTTCTGCGCACCCGCTTTGCAGCTCAGGGTGAGCCCAAGGTCTATAATACGCTGCGCCACGCCGT
GGGGACCATGTATAGGAGCGAAGGCCCCCAGGTTTTCTACAAAGGCTTGGCTCCCACCTTGATCGCCATCTTCCCCTACGCCGGGCTGCA
GTTCTCTTGCTACAGCTCCTTGAAGCACCTGTACAAGTGGGCCATACCAGCCGAAGGAAAGAAAAATGAGAACCTCCAAAACCTGCTTTG
TGGCAGTGGAGCTGGTGTCATCAGCAAGACCCTGACATATCCGCTGGACCTCTTCAAGAAGCGGCTACAGGTTGGAGGGTTTGAGCATGC
CAGAGCTGCCTTTGGCCAGGTACGGAGATACAAGGGCCTCATGGACTGTGCCAAGCAGGTGCTGCAAAAGGAAGGCGCCCTGGGCTTCTT
CAAGGGCCTGTCCCCCAGCTTGCTGAAGGCTGCCCTCTCCACAGGCTTCATGTTCTTCTCGTATGAATTCTTCTGTAATGTCTTCCACTG
CATGAACAGGACAGCCAGCCAGCGCTGAGTGCAGGAAGGACCCCAGGTCTTCCCTGGAGGCAGCCTCCTGAAGGAAGGAAGATTCAGTCT
CCACTGAGAGGTGCCGTCTGGCCCTTCCCTGCAGGCCAGCTGCCCCAAGCGGGGTAGCAGCCTTGAACCCACCCAGCTGGGACACCACCA
GAAGGTCCAGGGCTCTCCCCATGAGAGAATCAGAGGGAATGCAGGACGTGGTCTATGGTGAGCCAACGACACAGTGAGAAGGAGCAGGAA
GTTGCTGTTTCTCCTCTGACCAGCCCACACTCCAAAGGAAACAGACGCCATCCTACACCTATCAGCCCTGCCTGCCAGGAGAACAGAACA


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FusionGenePPI for GRB2_SLC25A19


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
GRB2CSF1R, PRRC2A, EGFR, ERBB2, ERBB3, ERBB4, MED28, BCR, GAB2, CBL, ETV6, LY6G6F, NEU3, SRC, PDE6G, DOCK1, FASLG, SHC1, SOS1, VAV2, VAV3, RACGAP1, IQGAP1, KRT7, KRT8, KRT17, KRT18, PLEC, EPPK1, BCAR1, WAS, MAP4K1, BLNK, IL2RB, SYN1, PDGFRB, KHDRBS1, PTPN6, PTPN11, SYK, CD22, GAB1, IRS1, TNFRSF1A, PTK2, SH3BP2, CD28, TNK2, KIT, SOCS1, PTPRA, CBLB, EPHA2, AXL, DAG1, MAP2, PLCG1, MST1R, ITGA2B, NCKIPSD, NTRK1, PTPN1, JAK2, GRB2, USP8, CSF3R, HTT, MET, LCP2, SNTA1, ABL1, LAT, FLT4, PIK3R1, FRS2, GAB3, VAV1, SH2B2, SH2B1, PRKAR1A, DCTN1, RET, CRK, PTPN22, JAK1, ARHGAP17, SHB, REPS2, OCRL, PDGFRA, PXN, PAG1, TRAT1, INSR, RAPGEF1, KDR, SELL, ADRB2, EPOR, SYNCRIP, ZAP70, IRS4, MUC1, ITK, LAT2, SH2B3, ANXA2, ARHGAP35, RASA1, PTPN12, CRKL, ADAM15, ADAM10, WASL, EPS15, IL6ST, SH3KBP1, EPHB1, MAP3K1, FLT3, RALGPS1, USP6NL, SPRY2, PTPRE, DNM1, HNRNPC, MAPK9, DRD3, CDKN1B, ALOX5, PIK3C2B, GHR, HCLS1, DTX1, LAX1, SOS2, DRD4, PTK2B, SKAP1, TOM1L1, SHKBP1, FGFR3, INPP5D, MICAL1, PLXNB1, OTUD5, STAMBP, ALK, NPM1, BTK, CSN2, DAB2, EP300, HNRNPK, HSPA5, MAP1A, ATP8, ND4, MYH9, MYH11, NCL, NFYB, PIK3R2, RBBP6, SLC1A2, SPTBN1, SS18, UBA52, UBC, WIPF1, MAP4K3, ASAP2, SYNJ2, DLGAP1, ARHGAP32, HELZ, PDCD6IP, HIPK3, DCTN2, TCERG1, KIF3A, MAP4K5, KIAA1549L, ABI3BP, PTPN23, ASAP1, ERRFI1, WDR44, USP53, RIF1, SH2D4A, GAREM, RBM33, MSI2, WIPF2, SH3D19, NAP1L5, STK32C, MYO18A, A2M, AEBP1, AGT, AHSG, ALAS2, STRADB, AMBP, APCS, APOH, SNRNP200, B2M, GPANK1, BPGM, CLU, DNAJA3, DNAJB11, ESD, FABP1, FHOD1, FN1, GC, H1F0, HP, IK, PBXIP1, POLR2A, PRKAB1, RNF10, TF, TFG, TSC2, ENO1, ITIH4, AP4S1, CUTA, POMP, C21orf58, CD164, C21orf91, CFH, COX6A1, ECHS1, FH, NADK, FTL, PRAP1, GSTK1, TCEAL8, POLR1D, RBP4, SHBG, WDR1, IRF5, PPP3CA, GIT1, CDC42, CASP2, ELAVL1, SYNM, AP2A2, DNM2, NCK1, UBASH3B, CUL3, DCUN1D1, LRRK1, INPPL1, ARAP1, KRT85, HSPA8, HSPG2, KRT86, KRT1, KRT81, KRT35, CAD, KRT10, KRT2, HSPA9, KRT83, CCT8, KRT9, KRT33B, HSP90AA1, DNM3, DYNC1H1, TUBB, KRT34, RPS19, HSPA1B, HSP90AB1, SKAP2, CCT4, EEF1A1P5, KRT6A, KRT14, TUBB4B, TUBA1C, KRT16, TCP1, CCT2, ACTB, FAM175B, CCT3, KRT5, KRT15, CLPX, EEF1G, PSMD11, CALM3, HSPA1L, KRT32, DARS, HSPD1, EEF1D, CNOT1, UBR4, AHNAK, CLTC, KRT36, KRT82, MFAP4, PSTPIP2, PSMC2, PSME1, PSMD14, CD2AP, FUS, BRE, KRT19, CTTN, KRT4, VASP, CCT7, KRT73, HNRNPU, BABAM1, HNRNPD, DRG1, IMPDH2, SERBP1, PIK3CA, TUBA4B, BRCC3, DOK3, HIST4H4, GAPDH, RUVBL1, PSMD13, RPS20, ACTL6A, RARS, CCT5, HSD17B4, TSG101, IRS2, PDE4D, SPRY1, SPRY4, VCAM1, ELMO2, WDR6, WDR77, SNX18, NISCH, YWHAZ, STARD10, YWHAE, SH3PXD2B, DOCK4, PEAK1, PIK3CB, SLC25A5, YWHAB, YWHAQ, PPP2R2A, SIRPA, SYNJ1, FGD6, PIK3AP1, KIRREL, YWHAG, GAREML, AGER, WIPF3, PTPN18, SLC25A13, CYFIP2, ARHGEF7, PPP1CA, CSK, PTPRJ, YWHAH, CSRP1, SH3PXD2A, TTYH2, PIK3R3, FLNA, ARHGAP12, RADIL, SH2D5, FAU, NCKAP1, DIAPH1, HGS, CLASP2, TEC, SLC25A6, HUNK, MLLT4, C1orf27, PPP1CC, HDGFRP3, SLAIN2, EPS15L1, IGF2BP1, PPP5C, GJA9, TAB1, ITGA4, BAG3, CKS2, FTH1, COPB1, PHACTR4, SF3B4, VIM, UBA1, PHC2, KPNA2, CTAGE5, PON2, ARHGEF5, CASC3, MLXIPL, WBP11, YLPM1, SHANK3, NKD2, SLX1A, ACTG1, CBR1, AP2A1, AP2B1, AP2M1, AP2S1, HIST1H3A, SMU1, SNRPD2, CD59, ABL2, AES, EPS8, LMO2, REL, TRIM27, TP53BP2, DDX17, IKZF3, ZBTB7B, ABI3, NUTM2F, DPPA4, HOMEZ, NIF3L1, ARHGAP9, LZTS2, LNX1, C1orf94, PNMA5, PRR22, INCA1, DOK1, FKBP2, FABP5, ITCH, ROS1, HEXB, ACAP1, PLEKHS1, AUNIP, UQCC2, CRBN, LMX1A, MYOZ1, PACRGL, PARD6A, PCDHB5, PPARA, RB1, SOCS4, TMEM128, TSPAN2, VCP, WDFY3, DBN1, E2F2, ARL6IP4, OLIG1, WBSCR27, ZMAT1, CLNK, CEP170, FBF1, MCM2, USP12, GFAP, NEFH, HNRNPA2B1, RPS27A, LGALS3BP, MYL12A, MYL12B, S100A8, S100A9, ESRRB, LIME1, KRAS, LTK, SHC2, SHC4, DUSP13, DUSP8, CYLD, VPS37B, NKX2-5, SPATA2L, MVB12A, ZMYM6, VPS28, DOCK5, THEMIS, RAC1, TRIM25SLC25A19MOV10, NXF1, CLTB, HUWE1, ZWINT, CHST15, POLR3E, PCDHB15, FAM134A, GEMIN7, C2orf47, DUSP6, PTPN22


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for GRB2_SLC25A19


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GRB2_SLC25A19


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneGRB2C0036341Schizophrenia2PSYGENET
TgeneSLC25A19C1846648MICROCEPHALY, AMISH TYPE (disorder)1CTD_human;ORPHANET;UNIPROT
TgeneSLC25A19C3150973THIAMINE METABOLISM DYSFUNCTION SYNDROME 4 (BILATERAL STRIATAL DEGENERATION AND PROGRESSIVE POLYNEUROPATHY TYPE)1ORPHANET;UNIPROT