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Fusion gene ID: 15343 |
FusionGeneSummary for GRAP2_ADSL |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GRAP2_ADSL | Fusion gene ID: 15343 | Hgene | Tgene | Gene symbol | GRAP2 | ADSL | Gene ID | 9402 | 158 |
| Gene name | GRB2 related adaptor protein 2 | adenylosuccinate lyase | |
| Synonyms | GADS|GRAP-2|GRB2L|GRBLG|GRID|GRPL|GrbX|Grf40|Mona|P38 | AMPS|ASASE|ASL | |
| Cytomap | 22q13.1 | 22q13.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | GRB2-related adapter protein 2GRB-2-like proteinGRB2-related protein with insert domainSH3-SH2-SH3 adapter MonaSH3-SH2-SH3 adaptor moleculeadapter protein GRIDgrf-40grf40 adapter proteingrowth factor receptor-binding proteingrowth factor receptor | adenylosuccinate lyaseadenylosuccinase | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | O75791 | P30566 | |
| Ensembl transtripts involved in fusion gene | ENST00000543252, ENST00000344138, ENST00000540310, ENST00000478445, ENST00000544756, ENST00000399090, ENST00000407075, | ENST00000216194, ENST00000454266, ENST00000342312, ENST00000480775, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 2 X 2 X 1=4 |
| # samples | 3 | 2 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: GRAP2 [Title/Abstract] AND ADSL [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ADSL | GO:0006167 | AMP biosynthetic process | 11428554 |
| Tgene | ADSL | GO:0051262 | protein tetramerization | 16973378 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SKCM | TCGA-Z2-A8RT-06A | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000543252 | ENST00000216194 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000543252 | ENST00000454266 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000543252 | ENST00000342312 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| 5CDS-intron | ENST00000543252 | ENST00000480775 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000344138 | ENST00000216194 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000344138 | ENST00000454266 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000344138 | ENST00000342312 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| 5CDS-intron | ENST00000344138 | ENST00000480775 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000540310 | ENST00000216194 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000540310 | ENST00000454266 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000540310 | ENST00000342312 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| 5CDS-intron | ENST00000540310 | ENST00000480775 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| 3UTR-3CDS | ENST00000478445 | ENST00000216194 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| 3UTR-3CDS | ENST00000478445 | ENST00000454266 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| 3UTR-3CDS | ENST00000478445 | ENST00000342312 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| 3UTR-intron | ENST00000478445 | ENST00000480775 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000544756 | ENST00000216194 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000544756 | ENST00000454266 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000544756 | ENST00000342312 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| 5CDS-intron | ENST00000544756 | ENST00000480775 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| intron-3CDS | ENST00000399090 | ENST00000216194 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| intron-3CDS | ENST00000399090 | ENST00000454266 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| intron-3CDS | ENST00000399090 | ENST00000342312 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| intron-intron | ENST00000399090 | ENST00000480775 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000407075 | ENST00000216194 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000407075 | ENST00000454266 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| In-frame | ENST00000407075 | ENST00000342312 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
| 5CDS-intron | ENST00000407075 | ENST00000480775 | GRAP2 | chr22 | 40362040 | + | ADSL | chr22 | 40745836 | + |
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FusionProtFeatures for GRAP2_ADSL |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GRAP2 | ADSL |
| Interacts with SLP-76 to regulate NF-AT activation.Binds to tyrosine-phosphorylated shc. | Catalyzes two non-sequential steps in de novo AMPsynthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarateplus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, andthereby also contributes to de novo IMP synthesis, and convertssuccinyladenosine monophosphate (SAMP) to AMP and fumarate.{ECO:0000269|PubMed:10888601}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >ADSL | chr22:40362040 | chr22:40745836 | ENST00000216194 | + | 0 | 13 | 111_112 | 51 | 485 | Region | Note=Substrate binding |
| Tgene | >ADSL | chr22:40362040 | chr22:40745836 | ENST00000216194 | + | 0 | 13 | 85_87 | 51 | 485 | Region | Note=Substrate binding |
| Tgene | >ADSL | chr22:40362040 | chr22:40745836 | ENST00000342312 | + | 0 | 12 | 111_112 | 51 | 426 | Region | Note=Substrate binding |
| Tgene | >ADSL | chr22:40362040 | chr22:40745836 | ENST00000342312 | + | 0 | 12 | 85_87 | 51 | 426 | Region | Note=Substrate binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >GRAP2 | chr22:40362040 | chr22:40745836 | ENST00000344138 | + | 1 | 8 | 1_56 | -88 | 331 | Domain | SH3 1 |
| Hgene | >GRAP2 | chr22:40362040 | chr22:40745836 | ENST00000344138 | + | 1 | 8 | 271_330 | -88 | 331 | Domain | SH3 2 |
| Hgene | >GRAP2 | chr22:40362040 | chr22:40745836 | ENST00000344138 | + | 1 | 8 | 58_149 | -88 | 331 | Domain | SH2 |
| Hgene | >GRAP2 | chr22:40362040 | chr22:40745836 | ENST00000407075 | + | 1 | 7 | 1_56 | -97 | 331 | Domain | SH3 1 |
| Hgene | >GRAP2 | chr22:40362040 | chr22:40745836 | ENST00000407075 | + | 1 | 7 | 271_330 | -97 | 331 | Domain | SH3 2 |
| Hgene | >GRAP2 | chr22:40362040 | chr22:40745836 | ENST00000407075 | + | 1 | 7 | 58_149 | -97 | 331 | Domain | SH2 |
| Tgene | ADSL | chr22:40362040 | chr22:40745836 | ENST00000216194 | + | 0 | 13 | 20_21 | 51 | 485 | Region | Note=Substrate binding%3B shared with neighboring subunit |
| Tgene | ADSL | chr22:40362040 | chr22:40745836 | ENST00000342312 | + | 0 | 12 | 20_21 | 51 | 426 | Region | Note=Substrate binding%3B shared with neighboring subunit |
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FusionGeneSequence for GRAP2_ADSL |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GRAP2_ENST00000543252_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_547aa MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVD YYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDN TDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASF LQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNP MRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMA MVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKV >In-frame_GRAP2_ENST00000543252_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_561aa MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVD YYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDN TSLILSRGVIKAYCNLRLPGSDSSPVSVSQLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLR FRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEK QQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIR QELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEE >In-frame_GRAP2_ENST00000543252_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_488aa MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVD YYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDN TDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASF LQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNP MRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMA >In-frame_GRAP2_ENST00000344138_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_587aa MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPG DFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAA EEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTV GKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASL GASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTA DTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHS >In-frame_GRAP2_ENST00000344138_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_601aa MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPG DFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAA EEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTSLILSRGVIKAYCNLRLPGSDSSPVSVSQLARVISRLADFAKERASLPT LGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYT RKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDS ANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLI >In-frame_GRAP2_ENST00000344138_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_528aa MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPG DFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAA EEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTV GKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASL GASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTA >In-frame_GRAP2_ENST00000540310_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_521aa MLEFVSLLARKDSNNSVSKPRHKLNPFSSKRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLG LPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLAD FAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKR AFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASV QWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVV >In-frame_GRAP2_ENST00000540310_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_535aa MLEFVSLLARKDSNNSVSKPRHKLNPFSSKRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLG LPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTSLILSRGVIKAYCNLRLPGSDSSPV SVSQLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVE QLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARH LMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCH >In-frame_GRAP2_ENST00000540310_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_462aa MLEFVSLLARKDSNNSVSKPRHKLNPFSSKRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLG LPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLAD FAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKR AFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASV QWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYE >In-frame_GRAP2_ENST00000544756_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_515aa MGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDE QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERA SLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERT LDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGD >In-frame_GRAP2_ENST00000544756_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_529aa MGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDE QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTSLILSRGVIKAYCNLRLPGSDSSPVSVSQLA RVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMV TEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVM DPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVL >In-frame_GRAP2_ENST00000544756_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_456aa MGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDE QIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERA SLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITG QTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERT LDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQVQRFLEEEVYPLLKPYESVMKVK >In-frame_GRAP2_ENST00000407075_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_587aa MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPG DFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAA EEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTV GKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASL GASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTA DTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHS >In-frame_GRAP2_ENST00000407075_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_601aa MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPG DFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAA EEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTSLILSRGVIKAYCNLRLPGSDSSPVSVSQLARVISRLADFAKERASLPT LGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYT RKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDS ANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLI >In-frame_GRAP2_ENST00000407075_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_528aa MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPG DFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQTLGLPITDEQIQEMKSNLENIDFKMAA EEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTV GKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASL GASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GRAP2_ENST00000543252_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_1641nt ATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAAC CAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAGCATGAGGAT GACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGAC TACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACA GATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTG ATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAAT ACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAA CGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGAT CTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTC CTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATC ACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGAC ATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCC ATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAA CGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATT TCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCC ATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGG GGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCT TTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTG >In-frame_GRAP2_ENST00000543252_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_1683nt ATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAAC CAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAGCATGAGGAT GACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGAC TACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACA GATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTG ATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAAT ACTAGTCTCATTCTGTCAAGGGGCGTGATCAAGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTCTCAGTCTCCCAA CTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAG CTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGC TTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAG ATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTG CTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAA CAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTT GTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCA TTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGG CAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGA GTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGT CCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAG >In-frame_GRAP2_ENST00000543252_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_1464nt ATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAAC CAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAGCATGAGGAT GACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGAC TACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACA GATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTG ATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAAT ACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAA CGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGAT CTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTC CTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATC ACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGAC ATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCC ATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAA CGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATT TCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCC ATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAG >In-frame_GRAP2_ENST00000344138_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_1761nt ATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAAC CAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCAC GAAGGCCTCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGG GACTTCTCCATCTCTGTCAGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAG AAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGA GAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCT GAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTT GGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTG ATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTT GGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTA AAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAA AAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTG GGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGC TCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCG CTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCA GATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCT TTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAG CAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCC CAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTG >In-frame_GRAP2_ENST00000344138_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_1803nt ATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAAC CAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCAC GAAGGCCTCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGG GACTTCTCCATCTCTGTCAGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAG AAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGA GAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCT GAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTT GGTGCTACTTCTTGCTATGTTGGAGACAATACTAGTCTCATTCTGTCAAGGGGCGTGATCAAGGCTTATTGCAACCTCCGCCTCCCAGGC TCAGACAGCTCTCCTGTCTCAGTCTCCCAACTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACA TTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAG AACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGA GATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACA CGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAAC CTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGC TGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGT GCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTG TACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGT AGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATA GAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCC CAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTG >In-frame_GRAP2_ENST00000344138_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_1584nt ATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAAC CAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCAC GAAGGCCTCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGG GACTTCTCCATCTCTGTCAGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAG AAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGA GAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCT GAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTT GGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTG ATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTT GGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTA AAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAA AAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTG GGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGC TCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCG CTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCA GATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCT TTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCC >In-frame_GRAP2_ENST00000540310_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_1563nt ATGCTTGAATTTGTCTCCCTTCTTGCCAGAAAGGATTCTAATAACTCGGTGTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAA AGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAAT AAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGT TTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTA CGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTAT GTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGAC TTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTT TGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACT CAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGA GCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAG ATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATAT AAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTC CAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACG CTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAAC ATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTT AAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTG GATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGC >In-frame_GRAP2_ENST00000540310_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_1605nt ATGCTTGAATTTGTCTCCCTTCTTGCCAGAAAGGATTCTAATAACTCGGTGTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAA AGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAAT AAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGT TTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTA CGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTAT GTTGGAGACAATACTAGTCTCATTCTGTCAAGGGGCGTGATCAAGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTC TCAGTCTCCCAACTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTC CAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGA GATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAG CAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAA GTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAA CCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCAC CTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGT TTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAA CGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCAT GAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGAT GCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTC >In-frame_GRAP2_ENST00000540310_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_1386nt ATGCTTGAATTTGTCTCCCTTCTTGCCAGAAAGGATTCTAATAACTCGGTGTCAAAGCCAAGACATAAACTCAACCCCTTCTCTTCCAAA AGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAAT AAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGT TTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTA CGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTAT GTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGAC TTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTT TGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACT CAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGA GCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAG ATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATAT AAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTC CAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACG CTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAAC ATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAA >In-frame_GRAP2_ENST00000544756_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_1545nt ATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAGGATGACGTT CAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTAC AGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAA CAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCT CACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGAC TTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCC AGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGC ATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAG CTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGG CAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGC CTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGT TCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACA CTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAA GGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTC AAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGAC AATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACT GGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCA >In-frame_GRAP2_ENST00000544756_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_1587nt ATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAGGATGACGTT CAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTAC AGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAA CAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCT CACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTAGT CTCATTCTGTCAAGGGGCGTGATCAAGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTCTCAGTCTCCCAACTTGCC AGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACC ACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGG GGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTG ACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCT AGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAG ATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATG GACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTT ACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAG CTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTT TCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATT CACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTAT >In-frame_GRAP2_ENST00000544756_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_1368nt ATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAGGATGACGTT CAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTAC AGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAA CAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCT CACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGAC TTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCC AGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGC ATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAG CTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGG CAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGC CTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGT TCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACA CTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAA GGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTC AAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAA >In-frame_GRAP2_ENST00000407075_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_1761nt ATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAAC CAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCAC GAAGGCCTCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGG GACTTCTCCATCTCTGTCAGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAG AAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGA GAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCT GAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTT GGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTG ATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTT GGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTA AAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAA AAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTG GGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGC TCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCG CTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCA GATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCT TTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAG CAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCC CAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTG >In-frame_GRAP2_ENST00000407075_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_1803nt ATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAAC CAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCAC GAAGGCCTCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGG GACTTCTCCATCTCTGTCAGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAG AAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGA GAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCT GAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTT GGTGCTACTTCTTGCTATGTTGGAGACAATACTAGTCTCATTCTGTCAAGGGGCGTGATCAAGGCTTATTGCAACCTCCGCCTCCCAGGC TCAGACAGCTCTCCTGTCTCAGTCTCCCAACTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACA TTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAG AACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGA GATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACA CGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAAC CTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGC TGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGT GCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTG TACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGT AGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATA GAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCC CAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTG >In-frame_GRAP2_ENST00000407075_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_1584nt ATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAAC CAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCAC GAAGGCCTCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGG GACTTCTCCATCTCTGTCAGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAG AAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGA GAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCT GAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTT GGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTG ATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTT GGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTA AAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAA AAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTG GGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGC TCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCG CTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCA GATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCT TTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GRAP2_ENST00000543252_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_2366nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTC ACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTT GGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGA GACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGA CAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCA AACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCAC TGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCA CTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTC ACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAG CGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCAT AAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTG GATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAG ATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTT GCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGA CGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAA GTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAG GATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATC CAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTG CAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGG AAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTT AAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAG TTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTT TCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGG ACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAGTAAATACT >In-frame_GRAP2_ENST00000543252_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_2018nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTC ACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTT GGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGA GACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGA CAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCA AACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCAC TGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTAGTCTCATTCTGTCAAGGGGCGTG ATCAAGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTCTCAGTCTCCCAACTTGCCAGAGTGATCTCTCGGCTTGCC GACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGT CTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGC ACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAG AGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCAC AAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCA TATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCT GTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAAT ACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAG AACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTG GTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTA CTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAA AGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTG >In-frame_GRAP2_ENST00000543252_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_2181nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTC ACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTT GGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGA GACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGA CAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCA AACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCAC TGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCA CTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTC ACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAG CGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCAT AAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTG GATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAG ATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTT GCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGA CGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAA GTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAG GTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGT TGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTAC CTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTG AAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCC TTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACC TGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAGTAAAT >In-frame_GRAP2_ENST00000344138_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_2486nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTC ACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTT GGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAG AACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAG GATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTA GACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATC ACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGAT GTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGAC AATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAG GAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAG GATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGT TTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATC ATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACC GACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAAT CCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTT GAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAAC ATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATG GCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAA GGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCT TCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAG GTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAAT GCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTC TCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCAT ATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGA ATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAA >In-frame_GRAP2_ENST00000344138_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_2138nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTC ACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTT GGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAG AACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAG GATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTA GACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATC ACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGAT GTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGAC AATACTAGTCTCATTCTGTCAAGGGGCGTGATCAAGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTCTCAGTCTCC CAACTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCA CAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTG CGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGAC AAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCT GTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAA AAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACC CTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAG GCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATT CGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATC AGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTC AGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAG GAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAA >In-frame_GRAP2_ENST00000344138_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_2301nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTC ACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTT GGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAG AACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAG GATGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTA GACTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATC ACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGAT GTGATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGAC AATACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAG GAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAG GATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGT TTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATC ATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACC GACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAAT CCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTT GAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAAC ATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATG GCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATG AAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTAT AATGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACAT TTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGG CATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAG TGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTA >In-frame_GRAP2_ENST00000540310_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_2182nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACA ACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGA AGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACC TGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCT GTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCACTTG ACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACAC ATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTG TCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGG TAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATA TTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGG AGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCC GCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGA TCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAA TTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATT GCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGG TTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGA GATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGA GAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTAAAT TAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGA CTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCAC GTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGACTC AGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAGTAAATACTTAAA >In-frame_GRAP2_ENST00000540310_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_1834nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACA ACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGA AGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACC TGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCT GTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTAGTCTCATTCTGTCAAGGGGCGTGATCA AGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTCTCAGTCTCCCAACTTGCCAGAGTGATCTCTCGGCTTGCCGACT TTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTT GGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTC AGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAG CTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGA TTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATA AGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCC AGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGC TGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACA TCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTA AGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGG ATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCG TGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTT >In-frame_GRAP2_ENST00000540310_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_1997nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGGCATGAGGATGACGTTCAACACTTCAAGGTCATGCGAGACA ACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGACTACTACAGGACAAATTCCATCTCCAGACAGA AGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACC TGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGTGATGGCTCACGTGCACACATTTGGCCACTGCT GTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAATACTGACTTGATTATTCTTAGAAATGCACTTG ACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACAC ATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTG TCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGG TAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATA TTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGG AGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCC GCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGA TCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAA TTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGTGC AGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGA AGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGCCTTATTTTACCTCGAGAATTGTTACCTTA AATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTCAACAAGGCAAAAACAAAGAGCGTTGAAGT TGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATATTTTCCAGCTGCCTCAAGTTTAGTCCTTTT CACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAATTTGATCTAGGTCTAGCAAAATAACCTGGA CTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGTGATGAAGTTTGGAACTACAGTAAATACTT >In-frame_GRAP2_ENST00000544756_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_2394nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTC ACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAGAA CTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAGGA TGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGA CTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCAC AGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGT GATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAA TACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGA ACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGA TCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTT CCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCAT CACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGA CATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCC CATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGA ACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACAT TTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGC CATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGG GGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTC TTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGT GAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGC CTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTC AACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATAT TTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAAT TTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGT >In-frame_GRAP2_ENST00000544756_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_2046nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTC ACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAGAA CTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAGGA TGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGA CTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCAC AGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGT GATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAA TACTAGTCTCATTCTGTCAAGGGGCGTGATCAAGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTCTCAGTCTCCCA ACTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACA GCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCG CTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAA GATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGT GCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAA ACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCT TGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGC ATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCG GCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAG AGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAG TCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGA GGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATC >In-frame_GRAP2_ENST00000544756_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_2209nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGCTTCACGTTACAGCATGGAAGCTGTTGCCAAGTTTGATTTC ACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAGAA CTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAGGA TGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGA CTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCAC AGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGT GATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAA TACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGA ACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGA TCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTT CCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCAT CACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGA CATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCC CATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGA ACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACAT TTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGC CATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAA GGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAA TGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTT CTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCA TATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTG AATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATA >In-frame_GRAP2_ENST00000407075_chr22_40362040_+_ADSL_ENST00000216194_chr22_40745836_+_2394nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTTGG GAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAGAA CTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAGGA TGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGA CTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCAC AGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGT GATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAA TACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGA ACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGA TCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTT CCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCAT CACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGA CATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCC CATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGA ACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACAT TTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGC CATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAGAGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGG GGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAGTCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTC TTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGT GAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAATGC CTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTTCTC AACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCATAT TTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTGAAT TTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATAAGT >In-frame_GRAP2_ENST00000407075_chr22_40362040_+_ADSL_ENST00000454266_chr22_40745836_+_2046nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTTGG GAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAGAA CTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAGGA TGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGA CTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCAC AGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGT GATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAA TACTAGTCTCATTCTGTCAAGGGGCGTGATCAAGGCTTATTGCAACCTCCGCCTCCCAGGCTCAGACAGCTCTCCTGTCTCAGTCTCCCA ACTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGAACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACA GCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGATCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCG CTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTTCCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAA GATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCATCACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGT GCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGACATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAA ACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCCCATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCT TGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGAACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGC ATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACATTTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCG GCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTCAAAGCTGGAGGTAGCCGCCAGGATTGCCATGAGAAAATCAG AGTGCTTTCTCAGCAGGCAGCTTCTGTGGTTAAGCAGGAAGGGGGTGACAATGACCTCATAGAGCGTATCCAGGTTGATGCCTACTTCAG TCCCATTCACTCCCAGTTGGATCATTTACTGGATCCTTCTTCTTTCACTGGTCGTGCCTCCCAGCAGGTGCAGAGATTCTTAGAAGAGGA GGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAAGGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATC >In-frame_GRAP2_ENST00000407075_chr22_40362040_+_ADSL_ENST00000342312_chr22_40745836_+_2209nt GGGCAAAAAGCCACTGGGGGAGGCCAGTCCCGATCAGTCCTTTCTGGCTCCAGCTCCAGATCCCGTGCGGAGCAACAGCTGCGGTCGCAG TCTCCACCACCGCCTCCACCTCCATCGCCGTCGGGGGAGGGGCCGGCCGGACCCCGGGGTCACTGCCGAGGAATGAAGAGAGGCGGCCGG GCCCCGCGCTCCGCCCCGGCCTAGGGCCTTGCCCCGGGAGCCCGCGAGGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTTGG GAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAGAA CTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGCCAGAGCTCCCCAGGGGACTTCTCCATCTCTGTCAGGCATGAGGA TGACGTTCAACACTTCAAGGTCATGCGAGACAACAAGGGTAATTACTTTCTGTGGACTGAGAAGTTTCCATCCCTAAATAAGCTGGTAGA CTACTACAGGACAAATTCCATCTCCAGACAGAAGCAGATCTTCCTTAGAGACAGAACCCGAGAAGACCAGACATTGGGTTTGCCTATCAC AGATGAACAAATCCAGGAGATGAAATCAAACCTGGAGAACATCGACTTCAAGATGGCAGCTGAGGAAGAGAAACGTTTACGACATGATGT GATGGCTCACGTGCACACATTTGGCCACTGCTGTCCAAAAGCTGCAGGCATTATTCACCTTGGTGCTACTTCTTGCTATGTTGGAGACAA TACTGACTTGATTATTCTTAGAAATGCACTTGACCTGCTTTTGCCAAAGCTTGCCAGAGTGATCTCTCGGCTTGCCGACTTTGCTAAGGA ACGAGCCAGTCTACCCACATTAGGTTTCACACATTTCCAGCCTGCACAGCTGACCACAGTTGGGAAACGTTGCTGTCTTTGGATTCAGGA TCTTTGCATGGATCTCCAGAACTTGAAGCGTGTCCGAGATGACCTGCGCTTCCGGGGAGTAAAGGGTACCACTGGCACTCAGGCCAGTTT CCTGCAGCTCTTTGAGGGAGATGACCATAAGGTAGAGCAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTTAAGAGAGCTTTCATCAT CACAGGGCAGACATATACACGAAAAGTGGATATTGAAGTACTGTCTGTGCTGGCTAGCTTGGGGGCATCAGTGCACAAGATTTGCACCGA CATACGCCTCCTGGCAAACCTCAAGGAGATGGAGGAACCCTTTGAAAAACAGCAGATTGGCTCAAGTGCGATGCCATATAAGCGGAATCC CATGCGTTCAGAACGTTGCTGCAGTCTTGCCCGCCACCTGATGACCCTTGTCATGGACCCGCTACAGACAGCATCTGTCCAGTGGTTTGA ACGCACACTGGATGATAGTGCCAACCGACGGATCTGTTTGGCCGAGGCATTTCTTACCGCAGATACTATATTGAATACGCTGCAGAACAT TTCTGAAGGATTGGTCGTGTACCCCAAAGTAATTGAACGGCGCATTCGGCAAGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGC CATGGTCAAAGCTGGAGGTAGCCGCCAGGTGCAGAGATTCTTAGAAGAGGAGGTGTATCCCCTGTTAAAACCATATGAAAGCGTGATGAA GGTGAAAGCAGAATTATGTCTGTAGAGTTGGAAGAGAATTAAACGAAAATCATTGTTAATTGCTGAGGCATGAAAATTGTGTTACTATAA TGCCTTATTTTACCTCGAGAATTGTTACCTTAAATTAGTACAGCACTTTCTTCTTCCCATGGTGCTTTCCTGTTTCTCAGTCTCACATTT CTCAACAAGGCAAAAACAAAGAGCGTTGAAGTTGACTCTGCTCTTGCATAGTAAATGTAGTTCATACTTGATCTCTGTTCTTTCAAGGCA TATTTTCCAGCTGCCTCAAGTTTAGTCCTTTTCACGTGTTCATTTGCTTGTAAAGTAGCAAGAAATTTCTGGTCCTGTCTTCTAAAAGTG AATTTGATCTAGGTCTAGCAAAATAACCTGGACTCAGTGATTGAGTCAATGGTCAGATACCTTTTATTTCGGTTATTTTTGGCTAGTATA |
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FusionGenePPI for GRAP2_ADSL |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GRAP2 | GAB1, CCNDBP1, ZBTB7B, BEND5, HNRNPK, RBPMS, YWHAE, GFAP, KRTAP4-12, STAMBP, LCP2, CD28, SOS2, GNB2L1, KHDRBS1, MAP4K1, CSF1R, FASLG, LAX1, LAT, SYK, USP8, GAB2, BLNK, CBL, ALB, ERBB2, SPRY2, EGFR, CDC27, TNIP1, ZSCAN21, ANAPC5, PTPN23, ITCH, GAREM, TRIM68, SNX18, ANAPC1, ANAPC16, NAGK, CDC23, ANAPC7, ANAPC2, IFNAR2, KRAS, CBLB, RIN3, ABL1 | ADSL | USP15, USP4, DDA1, UBC, TYMS, NOV, CTSC, DNAJB1, DRG2, EHD4, EIF1AX, GTF2I, NPLOC4, PDE12, PLIN3, RAD23B, SAE1, UBQLN2, XPNPEP1, API5, BTF3L4, NT5C2, OXSR1, PAIP1, TWF1, WARS, WDR4, CALCOCO2, REL, NXF1, KLHL20, COMTD1, TEKT4, TEKT2, ABAT, CRIP1, G3BP1, G3BP2, GART, GPT2, LDHB, PFAS, RPE, SOD1, ALDH8A1, ATIC, PAICS, TPI1, NTRK1, MED4, SSX2IP, OFD1, CEP104, CEP152, CNTROB, FGFR1OP, CEP128, CEP135, CEP89, FBF1, RPGRIP1, CENPJ, MCM2, OTUB1, MTMR7, SNRNP27, FGB, ALOX5, USP47, GTF2E2, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GRAP2_ADSL |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for GRAP2_ADSL |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ADSL | C0268126 | Adenylosuccinate lyase deficiency (disorder) | 8 | CTD_human;ORPHANET;UNIPROT |
| Tgene | ADSL | C0004352 | Autistic Disorder | 1 | CTD_human;HPO |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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