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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 15291

FusionGeneSummary for GPR89B_DNM3

check button Fusion gene summary
Fusion gene informationFusion gene name: GPR89B_DNM3
Fusion gene ID: 15291
HgeneTgene
Gene symbol

GPR89B

DNM3

Gene ID

653519

26052

Gene nameG protein-coupled receptor 89Adynamin 3
SynonymsGPHR|GPR89|GPR89B|SH120|UNQ192Dyna III
Cytomap

1q21.1

1q24.3

Type of geneprotein-codingprotein-coding
DescriptionGolgi pH regulator Aprotein GPR89putative MAPK-activating protein PM01putative NF-kappa-B-activating protein 90dynamin-3T-dynamindynamin family memberdynamin, testicular
Modification date2018052320180523
UniProtAcc

P0CG08

Q9UQ16

Ensembl transtripts involved in fusion geneENST00000314163, ENST00000488603, 
ENST00000358155, ENST00000367733, 
ENST00000355305, ENST00000367731, 
ENST00000520906, 
Fusion gene scores* DoF score3 X 2 X 2=1216 X 12 X 5=960
# samples 315
** MAII scorelog2(3/12*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(15/960*10)=-2.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GPR89B [Title/Abstract] AND DNM3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneGPR89B

GO:0051452

intracellular pH reduction

18794847


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDSARCTCGA-DX-A1KY-01AGPR89Bchr1

147400691

+DNM3chr1

172222713

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000314163ENST00000358155GPR89Bchr1

147400691

+DNM3chr1

172222713

+
5CDS-intronENST00000314163ENST00000367733GPR89Bchr1

147400691

+DNM3chr1

172222713

+
5CDS-intronENST00000314163ENST00000355305GPR89Bchr1

147400691

+DNM3chr1

172222713

+
5CDS-intronENST00000314163ENST00000367731GPR89Bchr1

147400691

+DNM3chr1

172222713

+
5CDS-intronENST00000314163ENST00000520906GPR89Bchr1

147400691

+DNM3chr1

172222713

+
intron-3CDSENST00000488603ENST00000358155GPR89Bchr1

147400691

+DNM3chr1

172222713

+
intron-intronENST00000488603ENST00000367733GPR89Bchr1

147400691

+DNM3chr1

172222713

+
intron-intronENST00000488603ENST00000355305GPR89Bchr1

147400691

+DNM3chr1

172222713

+
intron-intronENST00000488603ENST00000367731GPR89Bchr1

147400691

+DNM3chr1

172222713

+
intron-intronENST00000488603ENST00000520906GPR89Bchr1

147400691

+DNM3chr1

172222713

+

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FusionProtFeatures for GPR89B_DNM3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GPR89B

P0CG08

DNM3

Q9UQ16


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDNM3chr1:147400691chr1:172222713ENST00000355305+1421659_750563870DomainGED
TgeneDNM3chr1:147400691chr1:172222713ENST00000358155+1321659_750553864DomainGED
TgeneDNM3chr1:147400691chr1:172222713ENST00000367731+1320659_750553860DomainGED

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGPR89Bchr1:147400691chr1:172222713ENST00000314163+114114_13414456TransmembraneHelical
HgeneGPR89Bchr1:147400691chr1:172222713ENST00000314163+114150_17014456TransmembraneHelical
HgeneGPR89Bchr1:147400691chr1:172222713ENST00000314163+114290_31014456TransmembraneHelical
HgeneGPR89Bchr1:147400691chr1:172222713ENST00000314163+114343_36314456TransmembraneHelical
HgeneGPR89Bchr1:147400691chr1:172222713ENST00000314163+114378_39814456TransmembraneHelical
HgeneGPR89Bchr1:147400691chr1:172222713ENST00000314163+114425_44514456TransmembraneHelical
HgeneGPR89Bchr1:147400691chr1:172222713ENST00000314163+11446_6614456TransmembraneHelical
HgeneGPR89Bchr1:147400691chr1:172222713ENST00000314163+1145_2514456TransmembraneHelical
HgeneGPR89Bchr1:147400691chr1:172222713ENST00000314163+11479_9914456TransmembraneHelical
TgeneDNM3chr1:147400691chr1:172222713ENST00000355305+142128_294563870DomainDynamin-type G
TgeneDNM3chr1:147400691chr1:172222713ENST00000355305+1421515_621563870DomainPH
TgeneDNM3chr1:147400691chr1:172222713ENST00000358155+132128_294553864DomainDynamin-type G
TgeneDNM3chr1:147400691chr1:172222713ENST00000358155+1321515_621553864DomainPH
TgeneDNM3chr1:147400691chr1:172222713ENST00000367731+132028_294553860DomainDynamin-type G
TgeneDNM3chr1:147400691chr1:172222713ENST00000367731+1320515_621553860DomainPH
TgeneDNM3chr1:147400691chr1:172222713ENST00000355305+1421205_211563870Nucleotide bindingGTP
TgeneDNM3chr1:147400691chr1:172222713ENST00000355305+1421236_239563870Nucleotide bindingGTP
TgeneDNM3chr1:147400691chr1:172222713ENST00000355305+142138_46563870Nucleotide bindingGTP
TgeneDNM3chr1:147400691chr1:172222713ENST00000358155+1321205_211553864Nucleotide bindingGTP
TgeneDNM3chr1:147400691chr1:172222713ENST00000358155+1321236_239553864Nucleotide bindingGTP
TgeneDNM3chr1:147400691chr1:172222713ENST00000358155+132138_46553864Nucleotide bindingGTP
TgeneDNM3chr1:147400691chr1:172222713ENST00000367731+1320205_211553860Nucleotide bindingGTP
TgeneDNM3chr1:147400691chr1:172222713ENST00000367731+1320236_239553860Nucleotide bindingGTP
TgeneDNM3chr1:147400691chr1:172222713ENST00000367731+132038_46553860Nucleotide bindingGTP
TgeneDNM3chr1:147400691chr1:172222713ENST00000355305+1421136_139563870RegionG3 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000355305+1421205_208563870RegionG4 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000355305+1421235_238563870RegionG5 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000355305+142138_45563870RegionG1 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000355305+142164_66563870RegionG2 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000358155+1321136_139553864RegionG3 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000358155+1321205_208553864RegionG4 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000358155+1321235_238553864RegionG5 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000358155+132138_45553864RegionG1 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000358155+132164_66553864RegionG2 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000367731+1320136_139553860RegionG3 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000367731+1320205_208553860RegionG4 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000367731+1320235_238553860RegionG5 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000367731+132038_45553860RegionG1 motif
TgeneDNM3chr1:147400691chr1:172222713ENST00000367731+132064_66553860RegionG2 motif


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FusionGeneSequence for GPR89B_DNM3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_GPR89B_ENST00000314163_chr1_147400691_+_DNM3_ENST00000358155_chr1_172222713_+_325aa
MSFLIDSSIMITSQEKEKKYMLPLDNLKVRDVEKSFMSSKHIFALFNTEQRNVYKDYRFLELACDSQEDVDSWKASLLRAGVYPDKSVGN
NKAENDENGQAENFSMDPQLERQVETIRNLVDSYMSIINKCIRDLIPKTIMHLMINNVKDFINSELLAQLYSSEDQNTLMEESAEQAQRR
DEMLRMYQALKEALGIIGDISTATVSTPAPPPVDDSWIQHSRRSPPPSPTTQRRPTLSAPLARPTSGRGPAPAIPSPGPHSGAPPVPFRP


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_GPR89B_ENST00000314163_chr1_147400691_+_DNM3_ENST00000358155_chr1_172222713_+_975nt
ATGAGTTTCCTGATCGACTCCAGCATCATGATTACCTCCCAGGAAAAAGAAAAGAAGTACATGCTTCCCTTGGACAACCTGAAAGTTCGG
GATGTGGAAAAGAGCTTTATGTCTAGCAAGCACATCTTTGCACTCTTTAATACAGAGCAAAGGAATGTATACAAAGACTATCGCTTCCTT
GAGCTGGCATGTGATTCCCAGGAGGATGTCGACAGCTGGAAGGCATCTCTACTAAGAGCTGGGGTCTATCCTGACAAATCTGTAGGGAAC
AACAAAGCTGAAAATGATGAGAATGGACAAGCAGAAAACTTTTCCATGGACCCACAATTGGAGAGGCAAGTGGAGACCATTCGCAACCTC
GTAGACTCCTACATGTCCATTATCAACAAATGTATCCGAGATCTAATTCCAAAAACAATAATGCACCTTATGATCAATAACGTTAAAGAT
TTCATAAATTCCGAGCTCCTAGCACAGTTGTATTCTTCAGAGGACCAAAATACCCTGATGGAGGAATCTGCTGAGCAGGCTCAGCGCCGG
GATGAGATGCTTCGAATGTATCAAGCACTGAAAGAAGCCCTTGGGATAATTGGGGACATCAGCACAGCCACCGTGTCCACTCCGGCACCC
CCTCCAGTGGATGACTCCTGGATACAGCACTCTCGCAGGTCACCTCCTCCAAGCCCCACAACCCAAAGGAGGCCAACACTAAGTGCTCCC
CTCGCAAGGCCCACATCCGGCCGAGGACCAGCTCCTGCCATTCCCTCTCCTGGCCCCCACTCTGGGGCTCCTCCAGTCCCATTCCGTCCA
GGCCCATTACCTCCTTTCCCCAGCAGCAGTGACTCCTTCGGAGCCCCTCCACAAGTTCCATCTAGGCCTACGAGGGCCCCGCCCAGTGTC


* Fusion transcript sequences (Full-length transcript).
>In-frame_GPR89B_ENST00000314163_chr1_147400691_+_DNM3_ENST00000358155_chr1_172222713_+_5994nt
AGCTTGACGGCGTCGGGCTGGAGAGCCGCAGTCCCGGCTGCAGCACCTGGGAGAAGGCAGACCGTGTGAGGGGGCCTGTGGCCCCAGCGT
GCTGTGGCCTCCGGGAGTGGGAAGTGGAGGCAGGAGCCTTCCTTACACTTCGCCATGAGTTTCCTGATCGACTCCAGCATCATGATTACC
TCCCAGGAAAAAGAAAAGAAGTACATGCTTCCCTTGGACAACCTGAAAGTTCGGGATGTGGAAAAGAGCTTTATGTCTAGCAAGCACATC
TTTGCACTCTTTAATACAGAGCAAAGGAATGTATACAAAGACTATCGCTTCCTTGAGCTGGCATGTGATTCCCAGGAGGATGTCGACAGC
TGGAAGGCATCTCTACTAAGAGCTGGGGTCTATCCTGACAAATCTGTAGGGAACAACAAAGCTGAAAATGATGAGAATGGACAAGCAGAA
AACTTTTCCATGGACCCACAATTGGAGAGGCAAGTGGAGACCATTCGCAACCTCGTAGACTCCTACATGTCCATTATCAACAAATGTATC
CGAGATCTAATTCCAAAAACAATAATGCACCTTATGATCAATAACGTTAAAGATTTCATAAATTCCGAGCTCCTAGCACAGTTGTATTCT
TCAGAGGACCAAAATACCCTGATGGAGGAATCTGCTGAGCAGGCTCAGCGCCGGGATGAGATGCTTCGAATGTATCAAGCACTGAAAGAA
GCCCTTGGGATAATTGGGGACATCAGCACAGCCACCGTGTCCACTCCGGCACCCCCTCCAGTGGATGACTCCTGGATACAGCACTCTCGC
AGGTCACCTCCTCCAAGCCCCACAACCCAAAGGAGGCCAACACTAAGTGCTCCCCTCGCAAGGCCCACATCCGGCCGAGGACCAGCTCCT
GCCATTCCCTCTCCTGGCCCCCACTCTGGGGCTCCTCCAGTCCCATTCCGTCCAGGCCCATTACCTCCTTTCCCCAGCAGCAGTGACTCC
TTCGGAGCCCCTCCACAAGTTCCATCTAGGCCTACGAGGGCCCCGCCCAGTGTCCCAAGCCGGAGACCACCCCCATCACCAACTCGTCCC
ACTATAATCCGCCCACTAGAATCCTCCCTGTTAGACTAAACGAAGTGTCTGGCATGGCAATTAATCACTAATGAATTATGCGAAAGCAAC
ATATTTGATAACCGTTGCAGTAAATCATGAGTAGTCGCATGTGTGGACATCAGTAGGCAAGTAACCAGTTTTACTAATGCATTCATCGCT
CATCTTCATTGCTCATGGTATGTCAAACCTTTGGGGTTTGACTCAGAAACTGCTAACCTTTTAGAGGCTTTATATGTTGTACTGACCAAG
GTAGGTTTGTATAGCAGCCCTATACTTTGGGGATCATTTGCCTACCATGGCATATATTTGAAATTGCTTTGGACAAGTTTTCTAGGCTAT
CTACCAGGTAGCTCATTAAACGTAATTCTTCAGATATGAGATAGTGGGCTTAGACCTAAGCCATACATATTTCTTTTCCCACATTCTGTT
TAGGATGACAGTAATTCTGTTGTCTACCATTAATGCTACTACCTACTCCATAATTGCCTATTTAGCTCCTCTTTTCTTCCTTTTTATTTC
ATAAGACTGCTAGGAAGTGATTTTTTAAAATTAGGACTCCTTAAGAATAAACTTTTCCAGAAGCACGAGGTAGTTTGCAAAGGAAAAGTC
TGCACTGTTTGCTCTAAAGAGCTTCTCCTCATTCCAATGTGTTTTGCTTCATGCTAGAAGCATATGCAACAGTGAATAAAAGCTTCTTTT
TTTGTTAATCAGTCAATAAATTTGGCTAATTAGTTTCAGAGTTCAAGGAAGAAGCAAAATATCACATCTCTAGAAGTGTTGGGAAAAATA
TAATTTCTTTCTTTACTTATATTCACCTCATGGTAGGTTATATTGAAGGCTGACATGGAGAATGTTTACTTTTCTATTTGGCATAGCTAA
CTACACTTTGATACTAACTCCAGTTTTACTATTATTATTTTGGTTGGAAAAAAAATTCACTCTTTACGTGCTAATTTGTAATCTTGTTTT
GTAAGAATTTATCCTACCCTTGAAACAGGCTCAGTGTAACTGTATATCCATTCTAGGCTTTCTTAATAAATCTTGAGGCTATGGGATAAT
CACATTTAAAGAATGGTTCCTGAAATGAAGTCAGTAGAAATGGCATGGGATAAGAGCAGAGCTCACACTTTTACAGTTGCAGTATTTCAA
AGTCCCTATCCAGGTCACTCCAGAAAAGGGTATTGAAACGTTGAAATCTAAAGCAAATTTGCAATTTCTTAAGATTTCTAAAATTTACCA
GAACAGTTTAGCCTGGGGGTTAATAGTTAAGTCTTGAGGCTAAGTTTTGGACTACCAAGGACCAGATGATTCACATGTAGGAAACAGCCA
GAAGCCAACTGGAATTTTGTGTGCTAACTGTTCCCAGACAGCAGAGCAAGTATTCACTGAGTAGGGGTGTCCCATGACACTATTTCATAT
TCTACAGAAGTAAATCAGGTTTCACCAACTGAAATGTCTCCCTTTGAAAGTAGCAAACATGATTTGTATGTTAACTTAACTTTAATTTCC
TGTGTAGTTTACACCCAGAGCAGATACTCATAAAGTATAAAGTAAAAACTTTTAACCATTATTAAACAGAGAACTTGCCATGTTGAGTGC
CATTGTATTGAACTTATTCTAAAGGCTTATGCTAACCCATTTATAATTGGTAAAAATCAGAAAATACAAGATTTACATAAAGGTCATTTC
AACTTTTAAGGTTACCAGTGATTGTATAAAAACATCACAATCCTAAATCCTCTCGTATCTCACCCCAAACCCCAAACTGGGGGAAAAAAA
GTTAACTCTTTGTGAATGGAACCAATGTGCAAGATACATACTGCATTTTTAAAATAGTGTCTCAGCTAAATGGAAAACTGTTAAGCAAAC
ATCCATAGTAAAACAAATAATCTTCAGTGAGATCTTTTTATAAAACTTCTTGTTTTTAGGATTCCCTTTGCTTCTTCCTTTGAATTCTCT
AAAATAGGCAGCTAACGGATTATATACTTCAGGGTTTGGCTTTGTGCTAAATGTGGTTTTGTGTTTTGCTGTATTTCAAAATTTTCCTTC
TGTTAAAGGAAAATATTGTGAATAACCACTGGTGTGTTCTTAGATCAGCACAAACCATGTCAAAAAAAATTGGAGATTTTTTTCCAATTT
TCCTTCCACTGATCTTAGGCAGTAATAAACAATGGCATTTGTCATCTTTGGCACTTGCTTTTAGATTATAGTCCCACAGTTGCACTGCCC
CAATTGTCTACCTTTGTGGGTACATTTTTGTTCTTTACTCCTAAGTTATTTCTCATAGAACCCAGCCTACTCTAGAATTTCAGCAGTGAC
ATTGGAGAATATTTTTAATTTGCTGCAGTACTATGTCATATTATTAGTATGAATCTCATTTCCCAAAGGGTTTGTATTCTGCTAAAAGGA
GATGCCAATGTTGAATGAAGTCTGAAACTCTAGTATGTGCATAGTTTGACGTGCAGCATGCACACCAGGCCTTAAGATGGGAATGTAGCT
TAATGATTTTCTGTTTCCCATACCATTTCTAATCTTTTGTGTAATTTTCTCTTAACTGATTGCTCTGATATTGTAAACACAATAGATGTA
GCTCTATCATGTCTAGCATAATTTAAAAAATCAGTGTTTTTAGGATTTGGGAAAATAAACTGTAAATGTTTATTTGATAGGTAAATATAG
TTTTATTGTCACATGCTAAATATTGCATGCATATTGACTAATTGGAATAACCATTTACTCAATTATGGACAGCTTATTGAAATAGTATTG
ATTTAGAAAAAGTATATTGCATTTCTAAAAAACATCTACCAAGGTTACTCGTCTGAATATTGCTTTTAGCCGTGTTTTATAACATAGACG
AGCAGTAGGGTCTGTTTATTAGCAAATTTCCTATTTGTTCCAATACAAACTCACTTTATTCTAAAGTATATTAATGAAACCAGTTCCTGT
GATGTAACTGTAAGCCTTCTCGACTTAGACTTAAAAAGTGGTCACATAGATTAATTTTGTGACTTTTTAGTATAGACTGTAGCCATAATT
CTCAAATATGAAATGGGACCTAATACCAGTATGTGATAAATGTTGATGTTTTCTGTGTACAAACACATTTTCTATGCATGTGTCTCTGTG
TATATGGCATATACCTAGTAAGTATGTTTCTGTAAGTATGTGTATTTTATGTCCATTTGAGTAGGTAGGTAGGTTTTAAAAATACTAGTT
AAAATGCCACAAGCATGAGTGTGATTGTATGTGCACTGTGTGTATATATATAAATATATGTATATGTATGGTTGTAAATATCTATGTATA
CATGTACTTAGTATGTGTGGTATCAGGATATTTTTTAAACTGTGATAATACAACAGATAGCTTTGAATGATCTGCCATAACATGTGGTAA
CAATAGTTCATTTCTCATAACATATATGAGGTATACAAAATTTTCTAACTCCAGATTGTAGTCATTTTGAGAGGTACAAAGCTCATAATT
ACCATGACAACATGGTAATGTCCATAGACATTTGTATCTGAATCCACAAGAAGATCTGAATCTAAGAAGGAATTACCTTTGACAATATTT
TTCGGTAAGAAGTAAAACCTCTGGAGACCTATCTTTAAGATCTCTAATTGGAATTATAAATTATTTTTGGATTGCTGAGCTGAATCTTAA
AAAGCCAAGTTGATATACATAGTCATTTTTCCTCTATGGTAGAAGTAAAAAAAAAAAAAAAGGACATAGCAACATTAAAGTAGTGGATTT
TTCTGAGTAAATTTGCTGAAAATATAAGAGAGAAGCTATCTAATACCTTGGAGGTAGGTCATCCACTTTTTCAGGTAAACATTTTTCATT
TGGCAAATGGCATAATTATTTGAAAGTGACAGGAATCTCCTCAGAATGAAGAATAAAGCCTACTAGGTCTCTAACTGTTGAACTCATGAA
AGAAGATAGTGTATGAGACTTAAGCCATGAGTTTTGTATCATTTCAATTAGAAGACTACTAGCTGTGAGCTCAGAGTTTAATGTAAATGA
ATCTAGATGATTTTGAAGAAATGATTATTCGTTCACCAGATCACTCATTGTACATTCTAAAAAGCTCAAATGAGTCTTCTAGATACTCTT
ACTCATCCTGTCTGGTTGCTATGTTTAAAATTATGTGGTGCTGTGTAGGTGAAACTTTAAGAATATTTTTGAAGCATATGTAATATATGC
ACTGCTATTTGTGTGTGTGTGTGTGTCTTTGTATATATGTAAGAATGTGTGTATGTGTGAGAGCAAGAGAGAGGAAACTCAAAGAGGAGT
GTTTGTCTTAAGACCTGTTCATACTGGTATATTGGTGAGACTTCTCACTTCTGGTTGGAGGTTTCACATATGGCTCAACTCAAGTCATTA
ATCTCTTTTTAATTTTTACTCTTGAATTCCTTAAACTTCGCTCATTATGAAATGTTTTAAAATTATGACAAAAATTACTCTGTCTAACCA
CTTGCCTTGTCTGCTACCAGTTTGTTAAAAATTATTCCCCCCAACCAGTAATTCCACCAGTACTACTTGATTTGTGTTATATTTCCTATG
TACATGTACAGCCTTTGTTTTGCTTGCTTGTCTATTTTTACTTTCCCTTTTTTGGGTCAAATTTTTCTTTTGCTTTGTTTGAAGAAGGAA
TATACAGAAGTAAAATCTTGTCTTCTCTGCTGATTCTTTAATTAATATGAGCCGGATACTTTCCACTGTCTTCTTGGCACTTTCAGGATT
TCTTAATGCTGATATATGGACTCTTAGAATGGAATTTTTGAAGAAAAATCTCAAAGCCTGTATCGTTCTTGAAGGTCACATGTACCTATT


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FusionGenePPI for GPR89B_DNM3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
GPR89BTXNDC15, GABRE, LPAR6, B4GALT3, SERINC2, FNDC4, CCRL2, FAM134C, TMEM63A, GDPD5, P2RY1, ST3GAL1, SERINC1, APLNR, SLC4A8, MAS1, PIGSDNM3FER, SH3GL2, SH3GL3, GRB2, VCP, EFNB2, BSG, NUFIP1, DNAAF2, SPACA1, DNM1, DNM2, ALMS1, SNX5, COL1A1, KIF2C, SNX6, HECTD1, KIF11, SNX1, SNX2, HAUS8, HERC1, TP73, RAPH1, DNMBP, IGSF8, LYPD3, SCN2B, THBS3, LYPD6, GBE1, RPE, KRAS, SNX9, TMEM9B, ZBBX, GYPB, IL1R2, LAMP1, SLC2A12, GYPA, THRB, CDKAL1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for GPR89B_DNM3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GPR89B_DNM3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource