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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 14827

FusionGeneSummary for GNA13_CCDC171

check button Fusion gene summary
Fusion gene informationFusion gene name: GNA13_CCDC171
Fusion gene ID: 14827
HgeneTgene
Gene symbol

GNA13

CCDC171

Gene ID

10672

203238

Gene nameG protein subunit alpha 13coiled-coil domain containing 171
SynonymsG13C9orf93|bA536D16.1|bA778P13.1
Cytomap

17q24.1

9p22.3

Type of geneprotein-codingprotein-coding
Descriptionguanine nucleotide-binding protein subunit alpha-13g alpha-13guanine nucleotide binding protein (G protein), alpha 13coiled-coil domain-containing protein 171myosin tail domain containing protein
Modification date2018052320180519
UniProtAcc

Q14344

Q6TFL3

Ensembl transtripts involved in fusion geneENST00000439174, ENST00000541118, 
ENST00000297641, ENST00000380701, 
ENST00000535968, ENST00000486641, 
Fusion gene scores* DoF score9 X 3 X 8=2163 X 3 X 2=18
# samples 113
** MAII scorelog2(11/216*10)=-0.973527788638809
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: GNA13 [Title/Abstract] AND CCDC171 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDLUSCTCGA-60-2722-01AGNA13chr17

63049620

-CCDC171chr9

15846700

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000439174ENST00000297641GNA13chr17

63049620

-CCDC171chr9

15846700

+
In-frameENST00000439174ENST00000380701GNA13chr17

63049620

-CCDC171chr9

15846700

+
5CDS-intronENST00000439174ENST00000535968GNA13chr17

63049620

-CCDC171chr9

15846700

+
5CDS-intronENST00000439174ENST00000486641GNA13chr17

63049620

-CCDC171chr9

15846700

+
Frame-shiftENST00000541118ENST00000297641GNA13chr17

63049620

-CCDC171chr9

15846700

+
Frame-shiftENST00000541118ENST00000380701GNA13chr17

63049620

-CCDC171chr9

15846700

+
5CDS-intronENST00000541118ENST00000535968GNA13chr17

63049620

-CCDC171chr9

15846700

+
5CDS-intronENST00000541118ENST00000486641GNA13chr17

63049620

-CCDC171chr9

15846700

+

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FusionProtFeatures for GNA13_CCDC171


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GNA13

Q14344

CCDC171

Q6TFL3

Guanine nucleotide-binding proteins (G proteins) areinvolved as modulators or transducers in various transmembranesignaling systems (PubMed:15240885, PubMed:16787920,PubMed:16705036, PubMed:27084452). Activates effector moleculeRhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF,ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885,PubMed:12515866). GNA13-dependent Rho signaling subsequentlyregulates transcription factor AP-1 (activating protein-1) (Bysimilarity). Promotes tumor cell invasion and metastasis byactivating RhoA/ROCK signaling pathway (PubMed:16787920,PubMed:16705036, PubMed:27084452). Inhibits CDH1-mediated celladhesion in process independent from Rho activation(PubMed:11976333). {ECO:0000250|UniProtKB:P27601,ECO:0000269|PubMed:11976333, ECO:0000269|PubMed:12515866,ECO:0000269|PubMed:15240885, ECO:0000269|PubMed:16705036,ECO:0000269|PubMed:16787920, ECO:0000269|PubMed:27084452}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGNA13chr17:63049620chr9:15846700ENST00000439174-2458_63170378Nucleotide bindingGTP
TgeneCCDC171chr17:63049620chr9:15846700ENST00000297641+20251217_124110891230Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000380701+20261217_124110891327Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGNA13chr17:63049620chr9:15846700ENST00000439174-24197_200170378Nucleotide bindingGTP
HgeneGNA13chr17:63049620chr9:15846700ENST00000439174-24291_294170378Nucleotide bindingGTP
TgeneCCDC171chr17:63049620chr9:15846700ENST00000297641+2025323_39110891230Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000297641+2025450_56110891230Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000297641+202553_29410891230Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000297641+2025597_63010891230Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000297641+2025660_70710891230Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000297641+2025765_79210891230Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000297641+2025979_114310891230Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000380701+2026323_39110891327Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000380701+2026450_56110891327Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000380701+202653_29410891327Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000380701+2026597_63010891327Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000380701+2026660_70710891327Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000380701+2026765_79210891327Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000380701+2026979_114310891327Coiled coilOntology_term=ECO:0000255
TgeneCCDC171chr17:63049620chr9:15846700ENST00000297641+2025103_37710891230Compositional biasNote=Glu-rich
TgeneCCDC171chr17:63049620chr9:15846700ENST00000380701+2026103_37710891327Compositional biasNote=Glu-rich


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FusionGeneSequence for GNA13_CCDC171


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_GNA13_ENST00000439174_chr17_63049620_-_CCDC171_ENST00000297641_chr9_15846700_+_311aa
MADFLPSRSVLSVCFPGCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYS
NVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLSLSEAKMELR
RKDQSLRQLNRHLTQLEQDKRRLEENIHDAESALRMAAKDKECVANHMRAVENTLHKVRDQISLSWSAASRNDFTLQLPKLHLETFAMEG

>In-frame_GNA13_ENST00000439174_chr17_63049620_-_CCDC171_ENST00000380701_chr9_15846700_+_408aa
MADFLPSRSVLSVCFPGCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYS
NVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLSLSEAKMELR
RKDQSLRQLNRHLTQLEQDKRRLEENIHDAESALRMAAKDKECVANHMRAVENTLHKVRDQISLSWSAASRNDFTLQLPKLHLETFAMEG
LKGGPEVVACQAMIKSFMDVYQLASTRIMTLEKEMTSHRSHIAALKSELHTACLRENASLQSIGSRDHSNLSIPSRAPLPADTTGIGDFL


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_GNA13_ENST00000439174_chr17_63049620_-_CCDC171_ENST00000297641_chr9_15846700_+_933nt
ATGGCGGACTTCCTGCCGTCGCGGTCCGTGCTGTCCGTGTGCTTCCCCGGCTGCCTGCTGACGAGTGGCGAGGCCGAGCAGCAACGCAAG
TCCAAGGAGATCGACAAATGCCTGTCTCGGGAAAAGACCTATGTGAAGCGGCTGGTGAAGATCCTGCTGCTGGGCGCGGGCGAGAGCGGC
AAGTCCACCTTCCTGAAGCAGATGCGGATCATCCACGGGCAGGACTTCGACCAGCGCGCGCGCGAGGAGTTCCGCCCCACCATCTACAGC
AACGTGATCAAAGGTATGAGGGTGCTGGTTGATGCTCGAGAGAAGCTTCATATTCCCTGGGGAGACAACTCAAACCAACAACATGGAGAT
AAGATGATGTCGTTTGATACCCGGGCCCCCATGGCAGCCCAAGGAATGGTGGAAACAAGGGTTTTCTTACAATATCTTCCTGCTATAAGA
GCATTATGGGCAGACAGCGGCATACAGAATGCCTATGACCGGCGTCGAGAATTTCAACTGAGTCTCTCCGAGGCAAAGATGGAGCTGAGA
AGAAAAGATCAATCTCTGCGTCAGCTCAATAGACATCTTACCCAGCTGGAGCAGGACAAGCGTCGACTGGAGGAGAACATCCATGATGCA
GAGAGTGCCCTCCGCATGGCAGCCAAAGACAAAGAATGTGTTGCTAATCACATGAGAGCAGTAGAAAATACGCTTCACAAGGTCAGAGAT
CAGATCTCGCTGTCATGGTCTGCGGCAAGTAGGAATGACTTCACCCTACAGCTACCCAAACTGCACCTGGAGACCTTTGCAATGGAGGGG
CTCAAGGGCGGGCCAGAGGTGGTAGCATGCCAGGTTAGAGTGCAGTGGTGTGATCATAGCTCACTGCAGTCTCAAATGCCAGGGCTCAAG

>In-frame_GNA13_ENST00000439174_chr17_63049620_-_CCDC171_ENST00000380701_chr9_15846700_+_1224nt
ATGGCGGACTTCCTGCCGTCGCGGTCCGTGCTGTCCGTGTGCTTCCCCGGCTGCCTGCTGACGAGTGGCGAGGCCGAGCAGCAACGCAAG
TCCAAGGAGATCGACAAATGCCTGTCTCGGGAAAAGACCTATGTGAAGCGGCTGGTGAAGATCCTGCTGCTGGGCGCGGGCGAGAGCGGC
AAGTCCACCTTCCTGAAGCAGATGCGGATCATCCACGGGCAGGACTTCGACCAGCGCGCGCGCGAGGAGTTCCGCCCCACCATCTACAGC
AACGTGATCAAAGGTATGAGGGTGCTGGTTGATGCTCGAGAGAAGCTTCATATTCCCTGGGGAGACAACTCAAACCAACAACATGGAGAT
AAGATGATGTCGTTTGATACCCGGGCCCCCATGGCAGCCCAAGGAATGGTGGAAACAAGGGTTTTCTTACAATATCTTCCTGCTATAAGA
GCATTATGGGCAGACAGCGGCATACAGAATGCCTATGACCGGCGTCGAGAATTTCAACTGAGTCTCTCCGAGGCAAAGATGGAGCTGAGA
AGAAAAGATCAATCTCTGCGTCAGCTCAATAGACATCTTACCCAGCTGGAGCAGGACAAGCGTCGACTGGAGGAGAACATCCATGATGCA
GAGAGTGCCCTCCGCATGGCAGCCAAAGACAAAGAATGTGTTGCTAATCACATGAGAGCAGTAGAAAATACGCTTCACAAGGTCAGAGAT
CAGATCTCGCTGTCATGGTCTGCGGCAAGTAGGAATGACTTCACCCTACAGCTACCCAAACTGCACCTGGAGACCTTTGCAATGGAGGGG
CTCAAGGGCGGGCCAGAGGTGGTAGCATGCCAGGCTATGATTAAAAGTTTCATGGATGTCTACCAGCTTGCAAGCACTAGAATCATGACA
TTAGAGAAGGAAATGACATCTCATCGAAGTCACATTGCAGCCTTGAAATCAGAACTTCACACAGCTTGTTTACGTGAAAATGCAAGTTTA
CAATCAATAGGATCACGAGACCATTCAAATCTCTCCATTCCTTCAAGAGCTCCTCTTCCTGCTGACACAACTGGTATTGGGGATTTCTTA
CCATTGAAAGCTGAACTTGATACTACTTACACTTTCTTAAAGGAGACATTTATAAATACTGTGCCCCATGCTCTGACATCATCTCACTCC


* Fusion transcript sequences (Full-length transcript).
>In-frame_GNA13_ENST00000439174_chr17_63049620_-_CCDC171_ENST00000297641_chr9_15846700_+_1179nt
GCTCCGGGGCCACCGCCCCTCCGGGGCCGGGCCCGCCCTCCTTCCCTCCCTCCCTCCCCCGCTGTCCTGGCCCGCCCTGCCCGGCCCGCC
CTGCGAGTCAGTTCGCTGGTTCCCTCCCTCCCTGGGCGCGCTCGGGCCGCCGCCGCGCTCCCCGCCCTCGAGCCTCGGTGCCGGAGCCGC
CCGCCGCCGGAGGAGGAGGTGGAGGGAGCCGGAGGGGCCCGCCGAGGCGGCGGCGGCGGCGGCAAGATGGCGGACTTCCTGCCGTCGCGG
TCCGTGCTGTCCGTGTGCTTCCCCGGCTGCCTGCTGACGAGTGGCGAGGCCGAGCAGCAACGCAAGTCCAAGGAGATCGACAAATGCCTG
TCTCGGGAAAAGACCTATGTGAAGCGGCTGGTGAAGATCCTGCTGCTGGGCGCGGGCGAGAGCGGCAAGTCCACCTTCCTGAAGCAGATG
CGGATCATCCACGGGCAGGACTTCGACCAGCGCGCGCGCGAGGAGTTCCGCCCCACCATCTACAGCAACGTGATCAAAGGTATGAGGGTG
CTGGTTGATGCTCGAGAGAAGCTTCATATTCCCTGGGGAGACAACTCAAACCAACAACATGGAGATAAGATGATGTCGTTTGATACCCGG
GCCCCCATGGCAGCCCAAGGAATGGTGGAAACAAGGGTTTTCTTACAATATCTTCCTGCTATAAGAGCATTATGGGCAGACAGCGGCATA
CAGAATGCCTATGACCGGCGTCGAGAATTTCAACTGAGTCTCTCCGAGGCAAAGATGGAGCTGAGAAGAAAAGATCAATCTCTGCGTCAG
CTCAATAGACATCTTACCCAGCTGGAGCAGGACAAGCGTCGACTGGAGGAGAACATCCATGATGCAGAGAGTGCCCTCCGCATGGCAGCC
AAAGACAAAGAATGTGTTGCTAATCACATGAGAGCAGTAGAAAATACGCTTCACAAGGTCAGAGATCAGATCTCGCTGTCATGGTCTGCG
GCAAGTAGGAATGACTTCACCCTACAGCTACCCAAACTGCACCTGGAGACCTTTGCAATGGAGGGGCTCAAGGGCGGGCCAGAGGTGGTA
GCATGCCAGGTTAGAGTGCAGTGGTGTGATCATAGCTCACTGCAGTCTCAAATGCCAGGGCTCAAGCAATCTTCCTGCCTCAGCCTGCTG

>In-frame_GNA13_ENST00000439174_chr17_63049620_-_CCDC171_ENST00000380701_chr9_15846700_+_3673nt
GCTCCGGGGCCACCGCCCCTCCGGGGCCGGGCCCGCCCTCCTTCCCTCCCTCCCTCCCCCGCTGTCCTGGCCCGCCCTGCCCGGCCCGCC
CTGCGAGTCAGTTCGCTGGTTCCCTCCCTCCCTGGGCGCGCTCGGGCCGCCGCCGCGCTCCCCGCCCTCGAGCCTCGGTGCCGGAGCCGC
CCGCCGCCGGAGGAGGAGGTGGAGGGAGCCGGAGGGGCCCGCCGAGGCGGCGGCGGCGGCGGCAAGATGGCGGACTTCCTGCCGTCGCGG
TCCGTGCTGTCCGTGTGCTTCCCCGGCTGCCTGCTGACGAGTGGCGAGGCCGAGCAGCAACGCAAGTCCAAGGAGATCGACAAATGCCTG
TCTCGGGAAAAGACCTATGTGAAGCGGCTGGTGAAGATCCTGCTGCTGGGCGCGGGCGAGAGCGGCAAGTCCACCTTCCTGAAGCAGATG
CGGATCATCCACGGGCAGGACTTCGACCAGCGCGCGCGCGAGGAGTTCCGCCCCACCATCTACAGCAACGTGATCAAAGGTATGAGGGTG
CTGGTTGATGCTCGAGAGAAGCTTCATATTCCCTGGGGAGACAACTCAAACCAACAACATGGAGATAAGATGATGTCGTTTGATACCCGG
GCCCCCATGGCAGCCCAAGGAATGGTGGAAACAAGGGTTTTCTTACAATATCTTCCTGCTATAAGAGCATTATGGGCAGACAGCGGCATA
CAGAATGCCTATGACCGGCGTCGAGAATTTCAACTGAGTCTCTCCGAGGCAAAGATGGAGCTGAGAAGAAAAGATCAATCTCTGCGTCAG
CTCAATAGACATCTTACCCAGCTGGAGCAGGACAAGCGTCGACTGGAGGAGAACATCCATGATGCAGAGAGTGCCCTCCGCATGGCAGCC
AAAGACAAAGAATGTGTTGCTAATCACATGAGAGCAGTAGAAAATACGCTTCACAAGGTCAGAGATCAGATCTCGCTGTCATGGTCTGCG
GCAAGTAGGAATGACTTCACCCTACAGCTACCCAAACTGCACCTGGAGACCTTTGCAATGGAGGGGCTCAAGGGCGGGCCAGAGGTGGTA
GCATGCCAGGCTATGATTAAAAGTTTCATGGATGTCTACCAGCTTGCAAGCACTAGAATCATGACATTAGAGAAGGAAATGACATCTCAT
CGAAGTCACATTGCAGCCTTGAAATCAGAACTTCACACAGCTTGTTTACGTGAAAATGCAAGTTTACAATCAATAGGATCACGAGACCAT
TCAAATCTCTCCATTCCTTCAAGAGCTCCTCTTCCTGCTGACACAACTGGTATTGGGGATTTCTTACCATTGAAAGCTGAACTTGATACT
ACTTACACTTTCTTAAAGGAGACATTTATAAATACTGTGCCCCATGCTCTGACATCATCTCACTCCTCTCCAGTGACTATGTCTGCTAAT
GCCAACAGACCAACTCAGATTGGATTATGACTTCATGAAATTAAAAAATGGAGGAAGAGTTAACAGTACAATTAAAATTGTTTTGAATGG
GAATTTTCTTATCAGTTGACTTTTGTTTCAGCAGAAGTGGCAGTGGATTTAAAAAATTTGTGCGCTATCTTGATGTATTCTGGTAGCTCT
GTCTCCTTGAATAAGGAAATAGCCAACTTTTTTCTCTCCAAGTTTTATTTGTTATCACAGTTGCTCATTTTTATGTAACATATTTTTAAA
TGTTAAGGAATGACACATTTTGGGTAATTTCCCTCAGACTTAAAAAAATCAATAAGCCATTTTAGTCTCTATCTATCAAAGTTGTTTCAT
ACTTGTCTATTTTAAAGCAGGACTGCAATGCTTTAATAGGATTGAGAGAGCTATTTGAAATGTATGCCAATGATTCCTGTCATTTCATGG
CAGCCCGGCCATGGTTCACTGAGCCCCCTCTTCTCTCTTGTCAGCTCAACTGAAGACAAGCATTTAGTTGCAAACTTTAAGCAGGTTGTG
CAAAACAGAAATGATGTGACTGCTTCTCCTCCTGCACAATAATGTCACTCCTGGTCAATGTGAGAAGGTCAGGTTGCTCCTTGTAAAGCT
ACATGATACCACTTGCCCATTTGAACAAGTTAAGTTAACTGCTGAATCTGGTCCCTGAAGGCACTGAAAACTCATTCTTTTAGCAAGTCT
GCATTTGATAAGAAAGTAGAGCAATTGTGCTGGAGGATTTCTGTGGTATGTTTAGGCACTTCATAAGGACAGTTCCCACACTAGGATAGC
AGGTAATATATTTAGTATAAGCTGAAAAACTTCAAGGTAATGGCTGTTTTGACCTTCAAAATAGACTCCTTTTTTGTTTTTGTTGTTGGT
AGGACCCAAGAGTGACACCCATCTTTGATGCTGACAGAATTTAAAACAAGGCCATTGCCCTGCATTTTCTGCCTTGTAGCACACAAAAGT
AAAATTGTATGTCAGGCCGAGATGTCGGGGAGCTGACAAGATGCCCCAGTGACATTTCAGCTAGAAAGAGCAAGTGTCTTGCAACCAAGT
GGTCAAATATCAAATAATAGGTCAAGCAGGAAGGAGCTGAGTTCTAACCACAAAGAGGTTTCTGGTAACTTACTTGACAAGCTTTTGGGT
GCTTTGTGGCTTGACAAAGTGATGTTCTGTTGGGTATCGCTAGACAGACTGTTCTTTATCGCCTTCAGAAGATCAGACATTGACATTGAT
TAAACTCTTTAACCCTTAAAGGTTAAATCCTTGCAGTTTGCATCATGGTAAGTGAAGAACAAAAGAATATTTGTAGTAAGAATTTGTTTT
TGTATTAATCATTTAACTCCCTAGTGCTATTAACTTCTGATGTGAACTATAGCTTTTGACAAAGAGTCTTGATACATAATCTATTTTTTA
TATTATTTTTCATTATGGAATCTTTCATTATGGATACATTAGAGTATAACAGTATGTATTACAGAAGTTTTTTTGTCTTATCTTTACAGT
GACATTTGATTCAAATTACCCAACTGCTGAGAATTTTTTTATTGGCCTTGGTAAATAAGATTTTATACTAACTATTTATTAGTAGCCAAA
TTAGCCAAGTGATTTATGCCATCTGAGGGAACACAGCAGTATTACTGTCGTACTGTGTAACACATCCTATTCTTGTAATACTGAACCACT
ATAATTAGCTTTATATAAAACTTTAGAAAGCTTATATGGAGTAAAATTATATCTTTAACCAAATTTCTCTTAATTCTTTCCTTGGAATTA
TTTTTAATATGACCTGTGTAACATGACCTGTATGAAATTCAACTTGCAAATTTATTATAACATGGAAGTGCTATTTATTGTTTTTATACA
GATCATATAATTTCTGCACATTTCAGAACACCTTTCTCTGCTGTTCCAAACAATGATTAGGATATTGTTCATACAGAAATTGATAGACAA
TTTTTTAGTTCATGTGATATCACTGAGCTTACAATTCTCACTAGAGAAGAACAAGGTTACTATATGTAACCTCTATGTCTAAGTGTTTGT
GTGTGTGTATGCTTGTGTTGAATCTGTTTTCAGATCCTACTGATTTTAGAGGAACAAGCAGCTTTGTAAAATGTGCCTTGGAAAGGCCTT


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FusionGenePPI for GNA13_CCDC171


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
GNA13AKAP3, CDH1, CDH2, RGS16, ARHGEF1, DRD5, PPP5C, PRKCB, PRKCE, PRKCD, RDX, PTK2B, PRKAR2A, ARHGEF12, TEC, F2R, TBXA2R, MCF2, RIC8A, ARHGEF11, MAP3K5, ARHGEF28, USP3, AIP, ELAVL1, LRRK2, PRKACA, GNG2, AHR, CXCR5, CXCR4, CUL7, CCDC8, PHF19, SLC25A41, HOXB5, TAS2R7, FYTTD1, GNAI1, CCR1, TMEM185A, FAM63B, RD3, NTRK1, HERC2, GLI1, CDC73, GNG3, CYP2S1, PVR, FANCE, DUSP22, S1PR1, GNG4, TMEM206, TRIM25CCDC171KRAS


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for GNA13_CCDC171


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GNA13_CCDC171


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneGNA13C0006413Burkitt Lymphoma1CTD_human