|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 14795 |
FusionGeneSummary for GMDS_METTL24 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GMDS_METTL24 | Fusion gene ID: 14795 | Hgene | Tgene | Gene symbol | GMDS | METTL24 | Gene ID | 2762 | 728464 |
| Gene name | GDP-mannose 4,6-dehydratase | methyltransferase like 24 | |
| Synonyms | GMD|SDR3E1 | C6orf186 | |
| Cytomap | 6p25.3 | 6q21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | GDP-mannose 4,6 dehydrataseGDP-D-mannose dehydrataseshort chain dehydrogenase/reductase family 3E, member 1 | methyltransferase-like protein 24UPF0624 protein C6orf186 | |
| Modification date | 20180523 | 20180329 | |
| UniProtAcc | O60547 | Q5JXM2 | |
| Ensembl transtripts involved in fusion gene | ENST00000530927, ENST00000380815, ENST00000467288, | ENST00000338882, ENST00000490043, | |
| Fusion gene scores | * DoF score | 17 X 9 X 11=1683 | 4 X 4 X 4=64 |
| # samples | 17 | 4 | |
| ** MAII score | log2(17/1683*10)=-3.30742852519225 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: GMDS [Title/Abstract] AND METTL24 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | GMDS | GO:0019673 | GDP-mannose metabolic process | 9525924 |
| Hgene | GMDS | GO:0042351 | 'de novo' GDP-L-fucose biosynthetic process | 9525924 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-B6-A0I1-01A | GMDS | chr6 | 1930337 | - | METTL24 | chr6 | 110644075 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000530927 | ENST00000338882 | GMDS | chr6 | 1930337 | - | METTL24 | chr6 | 110644075 | - |
| 5CDS-5UTR | ENST00000530927 | ENST00000490043 | GMDS | chr6 | 1930337 | - | METTL24 | chr6 | 110644075 | - |
| In-frame | ENST00000380815 | ENST00000338882 | GMDS | chr6 | 1930337 | - | METTL24 | chr6 | 110644075 | - |
| 5CDS-5UTR | ENST00000380815 | ENST00000490043 | GMDS | chr6 | 1930337 | - | METTL24 | chr6 | 110644075 | - |
| intron-3CDS | ENST00000467288 | ENST00000338882 | GMDS | chr6 | 1930337 | - | METTL24 | chr6 | 110644075 | - |
| intron-5UTR | ENST00000467288 | ENST00000490043 | GMDS | chr6 | 1930337 | - | METTL24 | chr6 | 110644075 | - |
Top |
FusionProtFeatures for GMDS_METTL24 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GMDS | METTL24 |
| Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | GMDS | chr6:1930337 | chr6:110644075 | ENST00000380815 | - | 7 | 11 | 108_112 | 257 | 373 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1930337 | chr6:110644075 | ENST00000380815 | - | 7 | 11 | 30_35 | 257 | 373 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1930337 | chr6:110644075 | ENST00000380815 | - | 7 | 11 | 55_58 | 257 | 373 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1930337 | chr6:110644075 | ENST00000380815 | - | 7 | 11 | 86_87 | 257 | 373 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1930337 | chr6:110644075 | ENST00000530927 | - | 7 | 11 | 108_112 | 227 | 343 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1930337 | chr6:110644075 | ENST00000530927 | - | 7 | 11 | 30_35 | 227 | 343 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1930337 | chr6:110644075 | ENST00000530927 | - | 7 | 11 | 55_58 | 227 | 343 | Nucleotide binding | NADP |
| Hgene | GMDS | chr6:1930337 | chr6:110644075 | ENST00000530927 | - | 7 | 11 | 86_87 | 227 | 343 | Nucleotide binding | NADP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for GMDS_METTL24 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GMDS_ENST00000530927_chr6_1930337_-_METTL24_ENST00000338882_chr6_110644075_-_488aa MCKMDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDL AEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYGAAKLYAYWIVVNFREAYNLFAVNGILFNHE SPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEGPRWHIDLQPWAGSAQSLDEEAWRFLRYISTTQIACNHMNTDS LATDSSPTHKPWSVCLDDRFNLAHQIRNKQCRLYSLGLGSDDTHFEVSMANNGCEVHRFDPSVKSAHILESQHLWYHRLSIDWRDPHPAV AAQKPHSNTRKLGSILNEFGHHKIDVLKADLESAEWKVLENLILEDVLEQIGQLIFEIHLHWPGFEVSGSDSSVVRFWYSLLKELEQKDF >In-frame_GMDS_ENST00000380815_chr6_1930337_-_METTL24_ENST00000338882_chr6_110644075_-_518aa MAHAPARCPSARGSGDGEMGKPRNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDS TCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTSELYGKVQEIPQKETTPFYPRSPYG AAKLYAYWIVVNFREAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAKRDWGHAKDYVEGPRWHIDLQPWAG SAQSLDEEAWRFLRYISTTQIACNHMNTDSLATDSSPTHKPWSVCLDDRFNLAHQIRNKQCRLYSLGLGSDDTHFEVSMANNGCEVHRFD PSVKSAHILESQHLWYHRLSIDWRDPHPAVAAQKPHSNTRKLGSILNEFGHHKIDVLKADLESAEWKVLENLILEDVLEQIGQLIFEIHL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GMDS_ENST00000530927_chr6_1930337_-_METTL24_ENST00000338882_chr6_110644075_-_1464nt ATGTGTAAAATGGATGGTTCCTACCTGGCTGAGTTCCTGCTGGAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTT AATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCTCACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGT ACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAGATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTC GCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGACTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTC TACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAAATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGG GCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGTGAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAG AGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGCCGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTG GGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGACTATGTGGAGGGTCCCCGGTGGCATATAGATCTCCAGCCTTGGGCAGGC TCTGCTCAGTCCCTGGATGAAGAAGCCTGGAGGTTCCTGAGATATATCAGCACCACCCAGATTGCATGCAATCACATGAATACAGACAGC CTGGCTACTGACTCTAGTCCTACACACAAGCCCTGGTCAGTGTGTCTTGACGACAGGTTCAATTTAGCTCATCAAATCCGCAACAAGCAG TGCCGCCTCTACTCCTTAGGGCTAGGAAGTGATGATACCCATTTTGAGGTTAGCATGGCCAACAACGGATGTGAAGTGCATCGTTTTGAT CCTAGTGTCAAGTCAGCTCACATTCTGGAGAGTCAGCACCTTTGGTATCACCGCTTGTCCATTGACTGGCGGGATCCCCATCCAGCTGTT GCTGCCCAAAAACCACATAGCAACACCAGAAAACTGGGAAGCATTTTGAATGAATTTGGACATCACAAGATTGACGTTCTCAAGGCAGAT CTGGAAAGTGCAGAATGGAAAGTTTTGGAAAATCTTATTCTGGAAGATGTTCTTGAGCAGATTGGACAGCTCATCTTTGAGATCCATCTC CACTGGCCTGGGTTTGAGGTCAGTGGCAGTGACAGCAGCGTTGTGCGGTTCTGGTACAGCCTTCTCAAAGAGTTAGAACAAAAGGATTTC AGGCTTTTTCACAGTTACAAAGACTTATCTAAACCTCAGCTATTCTTGAAGAAAGACATTTTCAATGCAAGTAGCTGTTATACTCTGAGT >In-frame_GMDS_ENST00000380815_chr6_1930337_-_METTL24_ENST00000338882_chr6_110644075_-_1554nt ATGGCACACGCACCGGCACGCTGCCCCAGCGCCCGGGGCTCCGGGGACGGCGAGATGGGCAAGCCCAGGAACGTGGCGCTCATCACCGGT ATCACAGGCCAGGATGGTTCCTACCTGGCTGAGTTCCTGCTGGAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTT AATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCTCACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGT ACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAGATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTC GCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGACTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTC TACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAAATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGG GCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGTGAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAG AGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGCCGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTG GGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGACTATGTGGAGGGTCCCCGGTGGCATATAGATCTCCAGCCTTGGGCAGGC TCTGCTCAGTCCCTGGATGAAGAAGCCTGGAGGTTCCTGAGATATATCAGCACCACCCAGATTGCATGCAATCACATGAATACAGACAGC CTGGCTACTGACTCTAGTCCTACACACAAGCCCTGGTCAGTGTGTCTTGACGACAGGTTCAATTTAGCTCATCAAATCCGCAACAAGCAG TGCCGCCTCTACTCCTTAGGGCTAGGAAGTGATGATACCCATTTTGAGGTTAGCATGGCCAACAACGGATGTGAAGTGCATCGTTTTGAT CCTAGTGTCAAGTCAGCTCACATTCTGGAGAGTCAGCACCTTTGGTATCACCGCTTGTCCATTGACTGGCGGGATCCCCATCCAGCTGTT GCTGCCCAAAAACCACATAGCAACACCAGAAAACTGGGAAGCATTTTGAATGAATTTGGACATCACAAGATTGACGTTCTCAAGGCAGAT CTGGAAAGTGCAGAATGGAAAGTTTTGGAAAATCTTATTCTGGAAGATGTTCTTGAGCAGATTGGACAGCTCATCTTTGAGATCCATCTC CACTGGCCTGGGTTTGAGGTCAGTGGCAGTGACAGCAGCGTTGTGCGGTTCTGGTACAGCCTTCTCAAAGAGTTAGAACAAAAGGATTTC AGGCTTTTTCACAGTTACAAAGACTTATCTAAACCTCAGCTATTCTTGAAGAAAGACATTTTCAATGCAAGTAGCTGTTATACTCTGAGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GMDS_ENST00000530927_chr6_1930337_-_METTL24_ENST00000338882_chr6_110644075_-_1530nt TGTACACAGGCAGTTTGTTGGGAGCGTTACCATTGCCTCTGGTTCCTCATGTGTAAAATGGATGGTTCCTACCTGGCTGAGTTCCTGCTG GAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTTAATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCT CACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGTACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAG ATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTCGCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGA CTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTCTACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAA ATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGGGCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGT GAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAGAGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGC CGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTGGGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGAC TATGTGGAGGGTCCCCGGTGGCATATAGATCTCCAGCCTTGGGCAGGCTCTGCTCAGTCCCTGGATGAAGAAGCCTGGAGGTTCCTGAGA TATATCAGCACCACCCAGATTGCATGCAATCACATGAATACAGACAGCCTGGCTACTGACTCTAGTCCTACACACAAGCCCTGGTCAGTG TGTCTTGACGACAGGTTCAATTTAGCTCATCAAATCCGCAACAAGCAGTGCCGCCTCTACTCCTTAGGGCTAGGAAGTGATGATACCCAT TTTGAGGTTAGCATGGCCAACAACGGATGTGAAGTGCATCGTTTTGATCCTAGTGTCAAGTCAGCTCACATTCTGGAGAGTCAGCACCTT TGGTATCACCGCTTGTCCATTGACTGGCGGGATCCCCATCCAGCTGTTGCTGCCCAAAAACCACATAGCAACACCAGAAAACTGGGAAGC ATTTTGAATGAATTTGGACATCACAAGATTGACGTTCTCAAGGCAGATCTGGAAAGTGCAGAATGGAAAGTTTTGGAAAATCTTATTCTG GAAGATGTTCTTGAGCAGATTGGACAGCTCATCTTTGAGATCCATCTCCACTGGCCTGGGTTTGAGGTCAGTGGCAGTGACAGCAGCGTT GTGCGGTTCTGGTACAGCCTTCTCAAAGAGTTAGAACAAAAGGATTTCAGGCTTTTTCACAGTTACAAAGACTTATCTAAACCTCAGCTA TTCTTGAAGAAAGACATTTTCAATGCAAGTAGCTGTTATACTCTGAGTTGGGTGAATACAAGATGGAAATAGGATGCAGGATGTCATCAA >In-frame_GMDS_ENST00000380815_chr6_1930337_-_METTL24_ENST00000338882_chr6_110644075_-_1842nt GACGCGAATGACGCTGCGCCAGTCAGGCCGCAGCCCCGCTGCTTGGCCCGTCGGGCCCGCCTTGGCCGGCTCGGCCCGCCCCCGGCCCTC CCTGCACGGCCTCCCGTGCGCCCCTGTCAGACTGTGGCGGCCGGTCGCGCGGTGCGCTCTCCCTCCCTGCCCGCAGCCTGGAGAGGCGCT TCGTGCTGCACACCCCCGCGTTCCTGCCGGCACCGCGCCTGCCCTCTGCCGCGCTCCGCCCTGCCGCCGACCGCACGCCCGCCGCGGGAC ATGGCACACGCACCGGCACGCTGCCCCAGCGCCCGGGGCTCCGGGGACGGCGAGATGGGCAAGCCCAGGAACGTGGCGCTCATCACCGGT ATCACAGGCCAGGATGGTTCCTACCTGGCTGAGTTCCTGCTGGAGAAAGGCTATGAGGTCCATGGAATTGTACGGCGGTCCAGTTCATTT AATACGGGTCGAATTGAGCATCTGTATAAGAATCCCCAGGCTCACATTGAAGGAAACATGAAGTTGCACTATGGCGATCTCACTGACAGT ACCTGCCTTGTGAAGATCATTAATGAAGTAAAGCCCACAGAGATCTACAACCTTGGAGCCCAGAGCCACGTCAAAATTTCCTTTGACCTC GCTGAGTACACTGCGGACGTTGACGGAGTTGGCACTCTACGACTTCTAGATGCAGTTAAGACTTGTGGCCTTATCAACTCTGTGAAGTTC TACCAAGCCTCAACAAGTGAACTTTATGGGAAAGTGCAGGAAATACCCCAGAAGGAGACCACCCCTTTCTATCCCCGGTCACCCTATGGG GCAGCAAAACTCTATGCCTATTGGATTGTGGTGAACTTCCGTGAGGCGTATAATCTCTTTGCAGTGAACGGCATTCTCTTCAATCATGAG AGTCCCAGAAGAGGAGCTAATTTCGTTACTCGAAAAATTAGCCGGTCAGTAGCTAAGATTTACCTTGGACAACTGGAATGTTTCAGTTTG GGAAATCTGGATGCCAAACGAGATTGGGGCCATGCCAAGGACTATGTGGAGGGTCCCCGGTGGCATATAGATCTCCAGCCTTGGGCAGGC TCTGCTCAGTCCCTGGATGAAGAAGCCTGGAGGTTCCTGAGATATATCAGCACCACCCAGATTGCATGCAATCACATGAATACAGACAGC CTGGCTACTGACTCTAGTCCTACACACAAGCCCTGGTCAGTGTGTCTTGACGACAGGTTCAATTTAGCTCATCAAATCCGCAACAAGCAG TGCCGCCTCTACTCCTTAGGGCTAGGAAGTGATGATACCCATTTTGAGGTTAGCATGGCCAACAACGGATGTGAAGTGCATCGTTTTGAT CCTAGTGTCAAGTCAGCTCACATTCTGGAGAGTCAGCACCTTTGGTATCACCGCTTGTCCATTGACTGGCGGGATCCCCATCCAGCTGTT GCTGCCCAAAAACCACATAGCAACACCAGAAAACTGGGAAGCATTTTGAATGAATTTGGACATCACAAGATTGACGTTCTCAAGGCAGAT CTGGAAAGTGCAGAATGGAAAGTTTTGGAAAATCTTATTCTGGAAGATGTTCTTGAGCAGATTGGACAGCTCATCTTTGAGATCCATCTC CACTGGCCTGGGTTTGAGGTCAGTGGCAGTGACAGCAGCGTTGTGCGGTTCTGGTACAGCCTTCTCAAAGAGTTAGAACAAAAGGATTTC AGGCTTTTTCACAGTTACAAAGACTTATCTAAACCTCAGCTATTCTTGAAGAAAGACATTTTCAATGCAAGTAGCTGTTATACTCTGAGT |
Top |
FusionGenePPI for GMDS_METTL24 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GMDS | GMDS, TNKS, BLVRB, BAG3, ATIC, CAPN2, CTH, NSFL1C, PTMA, RAP1GDS1, TATDN1, WDYHV1, RNF166, MAT2B, RAB2A, TTC5, NDUFA9, PSMG4, CCDC22, SKA1, NF2, FBXW7, TNKS2, HIF1AN, NPHP3 | METTL24 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for GMDS_METTL24 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for GMDS_METTL24 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|