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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 14665

FusionGeneSummary for GIPR_RBM42

check button Fusion gene summary
Fusion gene informationFusion gene name: GIPR_RBM42
Fusion gene ID: 14665
HgeneTgene
Gene symbol

GIPR

RBM42

Gene ID

2696

79171

Gene namegastric inhibitory polypeptide receptorRNA binding motif protein 42
SynonymsPGQTL2-
Cytomap

19q13.32

19q13.12

Type of geneprotein-codingprotein-coding
Descriptiongastric inhibitory polypeptide receptorGIP-Rglucose-dependent insulinotropic polypeptide receptorRNA-binding protein 42
Modification date2018052320180523
UniProtAcc

P48546

Q9BTD8

Ensembl transtripts involved in fusion geneENST00000590918, ENST00000263281, 
ENST00000304207, ENST00000593127, 
ENST00000588161, ENST00000262633, 
ENST00000592202, ENST00000586618, 
ENST00000589559, ENST00000360475, 
ENST00000589871, 
Fusion gene scores* DoF score3 X 2 X 3=185 X 5 X 4=100
# samples 35
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GIPR [Title/Abstract] AND RBM42 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVESCATCGA-L5-A891-01AGIPRchr19

46173992

+RBM42chr19

36128060

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000590918ENST00000588161GIPRchr19

46173992

+RBM42chr19

36128060

+
In-frameENST00000590918ENST00000262633GIPRchr19

46173992

+RBM42chr19

36128060

+
In-frameENST00000590918ENST00000592202GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000590918ENST00000586618GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000590918ENST00000589559GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000590918ENST00000360475GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000590918ENST00000589871GIPRchr19

46173992

+RBM42chr19

36128060

+
In-frameENST00000263281ENST00000588161GIPRchr19

46173992

+RBM42chr19

36128060

+
In-frameENST00000263281ENST00000262633GIPRchr19

46173992

+RBM42chr19

36128060

+
In-frameENST00000263281ENST00000592202GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000263281ENST00000586618GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000263281ENST00000589559GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000263281ENST00000360475GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000263281ENST00000589871GIPRchr19

46173992

+RBM42chr19

36128060

+
In-frameENST00000304207ENST00000588161GIPRchr19

46173992

+RBM42chr19

36128060

+
In-frameENST00000304207ENST00000262633GIPRchr19

46173992

+RBM42chr19

36128060

+
In-frameENST00000304207ENST00000592202GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000304207ENST00000586618GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000304207ENST00000589559GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000304207ENST00000360475GIPRchr19

46173992

+RBM42chr19

36128060

+
5CDS-intronENST00000304207ENST00000589871GIPRchr19

46173992

+RBM42chr19

36128060

+
intron-3CDSENST00000593127ENST00000588161GIPRchr19

46173992

+RBM42chr19

36128060

+
intron-3CDSENST00000593127ENST00000262633GIPRchr19

46173992

+RBM42chr19

36128060

+
intron-3CDSENST00000593127ENST00000592202GIPRchr19

46173992

+RBM42chr19

36128060

+
intron-intronENST00000593127ENST00000586618GIPRchr19

46173992

+RBM42chr19

36128060

+
intron-intronENST00000593127ENST00000589559GIPRchr19

46173992

+RBM42chr19

36128060

+
intron-intronENST00000593127ENST00000360475GIPRchr19

46173992

+RBM42chr19

36128060

+
intron-intronENST00000593127ENST00000589871GIPRchr19

46173992

+RBM42chr19

36128060

+

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FusionProtFeatures for GIPR_RBM42


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
GIPR

P48546

RBM42

Q9BTD8

This is a receptor for GIP. The activity of thisreceptor is mediated by G proteins which activate adenylylcyclase. Binds (via the RRM domain) to the 3'-untranslated region(UTR) of CDKN1A mRNA. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRBM42chr19:46173992chr19:36128060ENST00000262633+710381_459378481DomainRRM
TgeneRBM42chr19:46173992chr19:36128060ENST00000360475+69381_459349452DomainRRM
TgeneRBM42chr19:46173992chr19:36128060ENST00000588161+69381_459348451DomainRRM

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314162_16957467Topological domainCytoplasmic
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314190_21757467Topological domainExtracellular
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+31422_13857467Topological domainExtracellular
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314243_25457467Topological domainCytoplasmic
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314279_29357467Topological domainExtracellular
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314320_34157467Topological domainCytoplasmic
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314363_37757467Topological domainExtracellular
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314399_46657467Topological domainCytoplasmic
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314139_16157467TransmembraneHelical%3B Name%3D1
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314170_18957467TransmembraneHelical%3B Name%3D2
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314218_24257467TransmembraneHelical%3B Name%3D3
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314255_27857467TransmembraneHelical%3B Name%3D4
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314294_31957467TransmembraneHelical%3B Name%3D5
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314342_36257467TransmembraneHelical%3B Name%3D6
HgeneGIPRchr19:46173992chr19:36128060ENST00000590918+314378_39857467TransmembraneHelical%3B Name%3D7
TgeneRBM42chr19:46173992chr19:36128060ENST00000262633+710180_343378481Compositional biasNote=Pro-rich
TgeneRBM42chr19:46173992chr19:36128060ENST00000360475+69180_343349452Compositional biasNote=Pro-rich
TgeneRBM42chr19:46173992chr19:36128060ENST00000588161+69180_343348451Compositional biasNote=Pro-rich


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FusionGeneSequence for GIPR_RBM42


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_GIPR_ENST00000590918_chr19_46173992_+_RBM42_ENST00000588161_chr19_36128060_+_160aa
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSDDFRIFCGDLGNEVNDDILARAFSRFPSFLKAK

>In-frame_GIPR_ENST00000590918_chr19_46173992_+_RBM42_ENST00000262633_chr19_36128060_+_160aa
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSDDFRIFCGDLGNEVNDDILARAFSRFPSFLKAK

>In-frame_GIPR_ENST00000590918_chr19_46173992_+_RBM42_ENST00000592202_chr19_36128060_+_160aa
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSDDFRIFCGDLGNEVNDDILARAFSRFPSFLKAK

>In-frame_GIPR_ENST00000263281_chr19_46173992_+_RBM42_ENST00000588161_chr19_36128060_+_160aa
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSDDFRIFCGDLGNEVNDDILARAFSRFPSFLKAK

>In-frame_GIPR_ENST00000263281_chr19_46173992_+_RBM42_ENST00000262633_chr19_36128060_+_160aa
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSDDFRIFCGDLGNEVNDDILARAFSRFPSFLKAK

>In-frame_GIPR_ENST00000263281_chr19_46173992_+_RBM42_ENST00000592202_chr19_36128060_+_160aa
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSDDFRIFCGDLGNEVNDDILARAFSRFPSFLKAK

>In-frame_GIPR_ENST00000304207_chr19_46173992_+_RBM42_ENST00000588161_chr19_36128060_+_160aa
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSDDFRIFCGDLGNEVNDDILARAFSRFPSFLKAK

>In-frame_GIPR_ENST00000304207_chr19_46173992_+_RBM42_ENST00000262633_chr19_36128060_+_160aa
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSDDFRIFCGDLGNEVNDDILARAFSRFPSFLKAK

>In-frame_GIPR_ENST00000304207_chr19_46173992_+_RBM42_ENST00000592202_chr19_36128060_+_160aa
MTTSPILQLLLRLSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSDDFRIFCGDLGNEVNDDILARAFSRFPSFLKAK


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_GIPR_ENST00000590918_chr19_46173992_+_RBM42_ENST00000588161_chr19_36128060_+_480nt
ATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAG
ACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTC
CGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAG
GTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAG
ATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAG

>In-frame_GIPR_ENST00000590918_chr19_46173992_+_RBM42_ENST00000262633_chr19_36128060_+_480nt
ATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAG
ACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTC
CGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAG
GTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAG
ATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAG

>In-frame_GIPR_ENST00000590918_chr19_46173992_+_RBM42_ENST00000592202_chr19_36128060_+_480nt
ATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAG
ACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTC
CGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAG
GTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAG
ATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAG

>In-frame_GIPR_ENST00000263281_chr19_46173992_+_RBM42_ENST00000588161_chr19_36128060_+_480nt
ATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAG
ACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTC
CGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAG
GTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAG
ATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAG

>In-frame_GIPR_ENST00000263281_chr19_46173992_+_RBM42_ENST00000262633_chr19_36128060_+_480nt
ATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAG
ACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTC
CGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAG
GTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAG
ATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAG

>In-frame_GIPR_ENST00000263281_chr19_46173992_+_RBM42_ENST00000592202_chr19_36128060_+_480nt
ATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAG
ACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTC
CGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAG
GTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAG
ATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAG

>In-frame_GIPR_ENST00000304207_chr19_46173992_+_RBM42_ENST00000588161_chr19_36128060_+_480nt
ATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAG
ACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTC
CGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAG
GTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAG
ATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAG

>In-frame_GIPR_ENST00000304207_chr19_46173992_+_RBM42_ENST00000262633_chr19_36128060_+_480nt
ATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAG
ACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTC
CGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAG
GTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAG
ATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAG

>In-frame_GIPR_ENST00000304207_chr19_46173992_+_RBM42_ENST00000592202_chr19_36128060_+_480nt
ATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAG
ACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTC
CGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAG
GTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAG
ATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAG


* Fusion transcript sequences (Full-length transcript).
>In-frame_GIPR_ENST00000590918_chr19_46173992_+_RBM42_ENST00000588161_chr19_36128060_+_711nt
GGCAGCGGTGGCAGGGGCTGCAGGAGCAAGTGACCAGGAGCAGGACTGGGGACAGGCCTGATCGCCCCTGCACGAACCAGACCCTTCGCC
GCCCTCACGATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCT
AAGGGGCAGACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCA
GATGACTTCCGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTT
AAGGCCAAGGTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCC
ATGCGTGAGATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGC
AAGAAGCAGAAGGAAAAGAAGAAGCTGGGCCTGAGATAGGGTCTGTGGCCAGGCACCCGCTCCCACCTGGCCGGGCGCTGGCTCCTCCCT

>In-frame_GIPR_ENST00000590918_chr19_46173992_+_RBM42_ENST00000262633_chr19_36128060_+_711nt
GGCAGCGGTGGCAGGGGCTGCAGGAGCAAGTGACCAGGAGCAGGACTGGGGACAGGCCTGATCGCCCCTGCACGAACCAGACCCTTCGCC
GCCCTCACGATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCT
AAGGGGCAGACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCA
GATGACTTCCGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTT
AAGGCCAAGGTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCC
ATGCGTGAGATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGC
AAGAAGCAGAAGGAAAAGAAGAAGCTGGGCCTGAGATAGGGTCTGTGGCCAGGCACCCGCTCCCACCTGGCCGGGCGCTGGCTCCTCCCT

>In-frame_GIPR_ENST00000590918_chr19_46173992_+_RBM42_ENST00000592202_chr19_36128060_+_680nt
GGCAGCGGTGGCAGGGGCTGCAGGAGCAAGTGACCAGGAGCAGGACTGGGGACAGGCCTGATCGCCCCTGCACGAACCAGACCCTTCGCC
GCCCTCACGATGACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCT
AAGGGGCAGACGGCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCA
GATGACTTCCGGATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTT
AAGGCCAAGGTGATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCC
ATGCGTGAGATGAATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGC
AAGAAGCAGAAGGAAAAGAAGAAGCTGGGCCTGAGATAGGGTCTGTGGCCAGGCACCCGCTCCCACCTGGCCGGGCGCTGGCTCCTCCCT

>In-frame_GIPR_ENST00000263281_chr19_46173992_+_RBM42_ENST00000588161_chr19_36128060_+_699nt
AGGGGCTGCAGGAGCAAGTGACCAGGAGCAGGACTGGGGACAGGCCTGATCGCCCCTGCACGAACCAGACCCTTCGCCGCCCTCACGATG
ACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAGACG
GCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTCCGG
ATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAGGTG
ATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAGATG
AATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAGAAG
GAAAAGAAGAAGCTGGGCCTGAGATAGGGTCTGTGGCCAGGCACCCGCTCCCACCTGGCCGGGCGCTGGCTCCTCCCTCAGTTCTCTTTG

>In-frame_GIPR_ENST00000263281_chr19_46173992_+_RBM42_ENST00000262633_chr19_36128060_+_699nt
AGGGGCTGCAGGAGCAAGTGACCAGGAGCAGGACTGGGGACAGGCCTGATCGCCCCTGCACGAACCAGACCCTTCGCCGCCCTCACGATG
ACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAGACG
GCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTCCGG
ATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAGGTG
ATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAGATG
AATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAGAAG
GAAAAGAAGAAGCTGGGCCTGAGATAGGGTCTGTGGCCAGGCACCCGCTCCCACCTGGCCGGGCGCTGGCTCCTCCCTCAGTTCTCTTTG

>In-frame_GIPR_ENST00000263281_chr19_46173992_+_RBM42_ENST00000592202_chr19_36128060_+_668nt
AGGGGCTGCAGGAGCAAGTGACCAGGAGCAGGACTGGGGACAGGCCTGATCGCCCCTGCACGAACCAGACCCTTCGCCGCCCTCACGATG
ACTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAGACG
GCGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTCCGG
ATCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAGGTG
ATCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAGATG
AATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAGAAG
GAAAAGAAGAAGCTGGGCCTGAGATAGGGTCTGTGGCCAGGCACCCGCTCCCACCTGGCCGGGCGCTGGCTCCTCCCTCAGTTCTCTTTG

>In-frame_GIPR_ENST00000304207_chr19_46173992_+_RBM42_ENST00000588161_chr19_36128060_+_698nt
GGGGCTGCAGGAGCAAGTGACCAGGAGCAGGACTGGGGACAGGCCTGATCGCCCCTGCACGAACCAGACCCTTCGCCGCCCTCACGATGA
CTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAGACGG
CGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTCCGGA
TCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAGGTGA
TCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAGATGA
ATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAGAAGG
AAAAGAAGAAGCTGGGCCTGAGATAGGGTCTGTGGCCAGGCACCCGCTCCCACCTGGCCGGGCGCTGGCTCCTCCCTCAGTTCTCTTTGG

>In-frame_GIPR_ENST00000304207_chr19_46173992_+_RBM42_ENST00000262633_chr19_36128060_+_698nt
GGGGCTGCAGGAGCAAGTGACCAGGAGCAGGACTGGGGACAGGCCTGATCGCCCCTGCACGAACCAGACCCTTCGCCGCCCTCACGATGA
CTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAGACGG
CGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTCCGGA
TCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAGGTGA
TCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAGATGA
ATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAGAAGG
AAAAGAAGAAGCTGGGCCTGAGATAGGGTCTGTGGCCAGGCACCCGCTCCCACCTGGCCGGGCGCTGGCTCCTCCCTCAGTTCTCTTTGG

>In-frame_GIPR_ENST00000304207_chr19_46173992_+_RBM42_ENST00000592202_chr19_36128060_+_667nt
GGGGCTGCAGGAGCAAGTGACCAGGAGCAGGACTGGGGACAGGCCTGATCGCCCCTGCACGAACCAGACCCTTCGCCGCCCTCACGATGA
CTACCTCTCCGATCCTGCAGCTGCTGCTGCGGCTCTCACTGTGCGGGCTGCTGCTCCAGAGGGCGGAGACAGGCTCTAAGGGGCAGACGG
CGGGGGAGCTGTACCAGCGCTGGGAACGGTACCGCAGGGAGTGCCAGGAGACCTTGGCAGCCGCGGAACCGCCTTCAGATGACTTCCGGA
TCTTCTGTGGGGATCTGGGCAATGAGGTGAACGATGACATCTTGGCACGCGCCTTCAGCCGCTTCCCATCCTTCCTTAAGGCCAAGGTGA
TCCGTGACAAGCGCACAGGCAAGACCAAGGGCTACGGCTTCGTCAGCTTCAAGGACCCCAGCGACTACGTGCGCGCCATGCGTGAGATGA
ATGGGAAGTATGTGGGCTCGCGCCCCATCAAGCTTCGCAAGAGCATGTGGAAGGACCGGAATCTGGACGTGGTCCGCAAGAAGCAGAAGG
AAAAGAAGAAGCTGGGCCTGAGATAGGGTCTGTGGCCAGGCACCCGCTCCCACCTGGCCGGGCGCTGGCTCCTCCCTCAGTTCTCTTTGG


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FusionGenePPI for GIPR_RBM42


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
GIPRLNX1RBM42HNRNPK, FHL3, PRPF4, COPS5, CAND1, PCBP1, APP, NUP88, NCL, NUCKS1, SF3B2, SNRPA, PPIL1, RBM4, RBFOX2, HECW2, PSMA3, SNRNP40, NTRK1, FAM103A1, METAP1, SMNDC1, CAMK2G, CAMK2B, CAMK2D, SNRNP27, RBM45, RAB11B, NGRN, PTCD1, TRUB2, QKI, RPUSD4, PRPF3, LSM5, SNRPE, MRPS9, RPUSD3, MTERF3, SART1, MRPS7, YARS2, SNRPG, MRPS5, SUPV3L1, RAP1GDS1, NADK, PTCD3, WBSCR16, MRPS2, MALSU1, ARIH1, SNRPN, FASTKD2, MRPS35, FAM120A, MRPS14, MRPS33, MRPS31, RPS14, MRPS26, CCDC60, SLC33A1, ZNF280A, MRPS21, PRPF6, MRPS24, CD2BP2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for GIPR_RBM42


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GIPR_RBM42


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneGIPRC0005910Body Weight1CTD_human
HgeneGIPRC0007131Non-Small Cell Lung Carcinoma1CTD_human