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Fusion gene ID: 14543 |
FusionGeneSummary for GDI2_IL2RA |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GDI2_IL2RA | Fusion gene ID: 14543 | Hgene | Tgene | Gene symbol | GDI2 | IL2RA | Gene ID | 2665 | 3559 |
| Gene name | GDP dissociation inhibitor 2 | interleukin 2 receptor subunit alpha | |
| Synonyms | HEL-S-46e|RABGDIB | CD25|IDDM10|IL2R|IMD41|TCGFR|p55 | |
| Cytomap | 10p15.1 | 10p15.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | rab GDP dissociation inhibitor betaGDI-2epididymis secretory sperm binding protein Li 46eguanosine diphosphate dissociation inhibitor 2rab GDI betarab GDP-dissociation inhibitor, beta | interleukin-2 receptor subunit alphaIL-2 receptor subunit alphaIL-2R subunit alphaTAC antigeninterleukin 2 receptor, alpha | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | P50395 | P01589 | |
| Ensembl transtripts involved in fusion gene | ENST00000380191, ENST00000479928, ENST00000380132, ENST00000380181, | ENST00000379959, ENST00000379954, ENST00000256876, | |
| Fusion gene scores | * DoF score | 6 X 6 X 4=144 | 3 X 3 X 3=27 |
| # samples | 6 | 3 | |
| ** MAII score | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: GDI2 [Title/Abstract] AND IL2RA [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | STAD | TCGA-BR-8373-01A | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000380191 | ENST00000379959 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| Frame-shift | ENST00000380191 | ENST00000379954 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| In-frame | ENST00000380191 | ENST00000256876 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| intron-3CDS | ENST00000479928 | ENST00000379959 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| intron-3CDS | ENST00000479928 | ENST00000379954 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| intron-3CDS | ENST00000479928 | ENST00000256876 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| Frame-shift | ENST00000380132 | ENST00000379959 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| Frame-shift | ENST00000380132 | ENST00000379954 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| In-frame | ENST00000380132 | ENST00000256876 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| Frame-shift | ENST00000380181 | ENST00000379959 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| Frame-shift | ENST00000380181 | ENST00000379954 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
| In-frame | ENST00000380181 | ENST00000256876 | GDI2 | chr10 | 5815805 | - | IL2RA | chr10 | 6054859 | - |
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FusionProtFeatures for GDI2_IL2RA |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GDI2 | IL2RA |
| Regulates the GDP/GTP exchange reaction of most Rabproteins by inhibiting the dissociation of GDP from them, and thesubsequent binding of GTP to them. | Receptor for interleukin-2. The receptor is involved inthe regulation of immune tolerance by controlling regulatory Tcells (TREGs) activity. TREGs suppress the activation andexpansion of autoreactive T-cells. {ECO:0000269|PubMed:23416241,ECO:0000269|PubMed:24116927}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for GDI2_IL2RA |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_GDI2_ENST00000380191_chr10_5815805_-_IL2RA_ENST00000256876_chr10_6054859_-_281aa MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKM LLYTEVTRYLDFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQD VIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKS >In-frame_GDI2_ENST00000380132_chr10_5815805_-_IL2RA_ENST00000256876_chr10_6054859_-_285aa MSLGKRKPSNFYLANFLGKECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQ LVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFD LGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVI >In-frame_GDI2_ENST00000380181_chr10_5815805_-_IL2RA_ENST00000256876_chr10_6054859_-_236aa MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGLMGLF EKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_GDI2_ENST00000380191_chr10_5815805_-_IL2RA_ENST00000256876_chr10_6054859_-_844nt ATGAATGAGGAGTACGACGTGATCGTGCTGGGCACCGGCCTGACGGAATGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTT CTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGA TCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTCAGCTGGTTAAGATG CTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAATCTACAAGGTTCCT TCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTC GATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGAC GTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAA CTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGG CTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCT >In-frame_GDI2_ENST00000380132_chr10_5815805_-_IL2RA_ENST00000256876_chr10_6054859_-_856nt ATGTCTCTAGGCAAGAGAAAACCTTCGAACTTTTATTTGGCTAATTTTTTAGGAAAGGAATGTATCCTGTCAGGTATAATGTCAGTGAAT GGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGATTT AAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTCAG CTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAATC TACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTAT GTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGAT TTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCATT AATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCAA GGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAATT >In-frame_GDI2_ENST00000380181_chr10_5815805_-_IL2RA_ENST00000256876_chr10_6054859_-_709nt ATGAATGAGGAGTACGACGTGATCGTGCTGGGCACCGGCCTGACGGAATGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTT CTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGA TCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGCCTAATGGGATTGTTT GAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAG ACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGAT GATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTT TATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_GDI2_ENST00000380191_chr10_5815805_-_IL2RA_ENST00000256876_chr10_6054859_-_1210nt AGAGTGCCGGGAGCGCCTGATTGGCGGCCCTCCCGGCGCCTGCAGGCCCCGCCCCGGCTGCGGAGGCTCAGTCACAGCCCTCCCCTCCTC GCTCCCTCCCCTCCTCTCCCCGCCCAGTTCTTCTCTTCCCGTCTGAGGTGGCGGTCGGTCTCGCCTTGTCGCCAGCTCCATTTTCCTCTC TTTCTCTTCCCCTTTCCTTCGCGCCCAAGAGCGCCTCCCAGCCTCGTAGGGTGGTCACGGAGCCCCTGCGCCTTTTCCTTGCTCGGGTCC TGCGTCCGCGCCTGCCCCGCCATGAATGAGGAGTACGACGTGATCGTGCTGGGCACCGGCCTGACGGAATGTATCCTGTCAGGTATAATG TCAGTGAATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATAC AAAAGATTTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCT AATGGTCAGCTGGTTAAGATGCTGCTTTATACAGAGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGT GGAAAAATCTACAAGGTTCCTTCCACTGAAGCAGAAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTC CTAGTGTATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAG AAATTTGATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTAT GAAACCATTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAA CTGCCCCAAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGA AAAGTAATTGGTGTAAAATCTGAAGGAGAAGAGGAAGAGTAGAAGAACAATCTAGAAAACCAAAAGAACAAGAATTTCTTGGTAAGAAGC >In-frame_GDI2_ENST00000380132_chr10_5815805_-_IL2RA_ENST00000256876_chr10_6054859_-_1176nt TTCTTCTCTTCCCGTCTGAGGTGGCGGTCGGTCTCGCCTTGTCGCCAGCTCCATTTTCCTCTCTTTCTCTTCCCCTTTCCTTCGCGCCCA AGAGCGCCTCCCAGCCTCGTAGGGTGGTCACGGAGCCCCTGCGCCTTTTCCTTGCTCGGGTCCTGCGTCCGCGCCTGCCCCGCCATGAAT GAGGAGTACGACGTGATCGTGCTGGGCACCGGCCTGACGGTAACATCCCAAAATAACACTTTTAGATGTCTCTAGGCAAGAGAAAACCTT CGAACTTTTATTTGGCTAATTTTTTAGGAAAGGAATGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTTCTTCATATGGATC GAAACCCTTACTACGGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGATCACCACCCGAGT CAATGGGGAGAGGAAGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGTCAGCTGGTTAAGATGCTGCTTTATACAG AGGTAACTCGCTATCTGGATTTTAAAGTGACTGAAGGGAGCTTTGTCTATAAGGGTGGAAAAATCTACAAGGTTCCTTCCACTGAAGCAG AAGCCCTGGCATCTAGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAGATC CAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATTTTA CTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTGAAT CTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTATTT ATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCTGAAGGAGAAGAGG AAGAGTAGAAGAACAATCTAGAAAACCAAAAGAACAAGAATTTCTTGGTAAGAAGCCGGGAACAGACAACAGAAGTCATGAAGCCCAAGT >In-frame_GDI2_ENST00000380181_chr10_5815805_-_IL2RA_ENST00000256876_chr10_6054859_-_937nt TGGCGGTCGGTCTCGCCTTGTCGCCAGCTCCATTTTCCTCTCTTTCTCTTCCCCTTTCCTTCGCGCCCAAGAGCGCCTCCCAGCCTCGTA GGGTGGTCACGGAGCCCCTGCGCCTTTTCCTTGCTCGGGTCCTGCGTCCGCGCCTGCCCCGCCATGAATGAGGAGTACGACGTGATCGTG CTGGGCACCGGCCTGACGGAATGTATCCTGTCAGGTATAATGTCAGTGAATGGCAAGAAAGTTCTTCATATGGATCGAAACCCTTACTAC GGAGGAGAGAGTGCATCTATAACACCATTGGAAGATTTATACAAAAGATTTAAAATACCAGGATCACCACCCGAGTCAATGGGGAGAGGA AGAGACTGGAATGTTGACTTGATTCCCAAGTTCCTTATGGCTAATGGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTA GTGTATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAA TTTGATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAA ACCATTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTG CCCCAAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAA GTAATTGGTGTAAAATCTGAAGGAGAAGAGGAAGAGTAGAAGAACAATCTAGAAAACCAAAAGAACAAGAATTTCTTGGTAAGAAGCCGG |
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FusionGenePPI for GDI2_IL2RA |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| GDI2 | RAB11A, RAB9A, RAB5A, RAB4A, RAB2A, RAB8A, RAB24, ELAVL1, SIRT7, ISG15, RAB11B, RAB1A, AIP, SMURF1, FN1, IQCB1, BAG3, GLRA2, DUT, HUWE1, RAB1B, RAB31, RASSF10, HSPB1, UNK, CLIC3, EZR, FH, ARHGDIG, RAB10, RAB8B, WDFY2, PLIN3, PREP, RAB7A, RDX, STIP1, STMN1, TAGLN3, TXNDC5, SKA3, MCM2, U2AF2, C10orf88, GDI1, RAB5C, H2AFY, RAB3A, RAB6B, TRIM25 | IL2RA | ICAM1, IL2RA, SNTA1, HGS |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for GDI2_IL2RA |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | IL2RA | P01589 | DB00041 | Aldesleukin | Interleukin-2 receptor subunit alpha | biotech | approved |
| Tgene | IL2RA | P01589 | DB00004 | Denileukin diftitox | Interleukin-2 receptor subunit alpha | biotech | approved|investigational |
| Tgene | IL2RA | P01589 | DB00074 | Basiliximab | Interleukin-2 receptor subunit alpha | biotech | approved|investigational |
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RelatedDiseases for GDI2_IL2RA |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | GDI2 | C0279626 | Squamous cell carcinoma of esophagus | 1 | CTD_human |
| Tgene | IL2RA | C0026769 | Multiple Sclerosis | 4 | CTD_human |
| Tgene | IL2RA | C0003873 | Rheumatoid Arthritis | 3 | CTD_human |
| Tgene | IL2RA | C0011854 | Diabetes Mellitus, Insulin-Dependent | 3 | CTD_human |
| Tgene | IL2RA | C1853392 | Interleukin 2 Receptor, Alpha, Deficiency of | 2 | CTD_human;ORPHANET;UNIPROT |
| Tgene | IL2RA | C0002171 | Alopecia Areata | 1 | CTD_human |
| Tgene | IL2RA | C0005138 | Berylliosis | 1 | CTD_human |
| Tgene | IL2RA | C0010346 | Crohn Disease | 1 | CTD_human |
| Tgene | IL2RA | C0017658 | Glomerulonephritis | 1 | CTD_human |
| Tgene | IL2RA | C0019693 | HIV Infections | 1 | CTD_human |
| Tgene | IL2RA | C0036341 | Schizophrenia | 1 | CTD_human |
| Tgene | IL2RA | C0041696 | Unipolar Depression | 1 | PSYGENET |
| Tgene | IL2RA | C0162820 | Dermatitis, Allergic Contact | 1 | CTD_human |
| Tgene | IL2RA | C0345967 | Malignant mesothelioma | 1 | CTD_human |
| Tgene | IL2RA | C1269683 | Major Depressive Disorder | 1 | PSYGENET |
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