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Fusion gene ID: 13962 |
FusionGeneSummary for FRS2_PIP4K2C |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FRS2_PIP4K2C | Fusion gene ID: 13962 | Hgene | Tgene | Gene symbol | FRS2 | PIP4K2C | Gene ID | 10818 | 79837 |
| Gene name | fibroblast growth factor receptor substrate 2 | phosphatidylinositol-5-phosphate 4-kinase type 2 gamma | |
| Synonyms | FRS1A|FRS2A|FRS2alpha|SNT|SNT-1|SNT1 | PIP5K2C | |
| Cytomap | 12q15 | 12q13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | fibroblast growth factor receptor substrate 2FGFR signalling adaptorFGFR substrate 2FGFR-signaling adaptor SNTsuc1-associated neurotrophic factor target 1 | phosphatidylinositol 5-phosphate 4-kinase type-2 gammaPI(5)P 4-kinase type II gammaPIP4KII-gammaphosphatidylinositol 4-phosphate 5-kinasephosphatidylinositol 5-phosphate 4-kinase type II gammaphosphatidylinositol-4-phosphate 5-kinase, type II, gamma | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | Q8WU20 | Q8TBX8 | |
| Ensembl transtripts involved in fusion gene | ENST00000299293, ENST00000549921, ENST00000550389, ENST00000397997, | ENST00000422156, ENST00000540759, ENST00000550465, ENST00000354947, | |
| Fusion gene scores | * DoF score | 56 X 9 X 12=6048 | 9 X 6 X 5=270 |
| # samples | 47 | 9 | |
| ** MAII score | log2(47/6048*10)=-3.68572547765607 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/270*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FRS2 [Title/Abstract] AND PIP4K2C [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-55-7907-01A | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000299293 | ENST00000422156 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000299293 | ENST00000540759 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000299293 | ENST00000550465 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000299293 | ENST00000354947 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000549921 | ENST00000422156 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000549921 | ENST00000540759 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000549921 | ENST00000550465 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000549921 | ENST00000354947 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000550389 | ENST00000422156 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000550389 | ENST00000540759 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000550389 | ENST00000550465 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000550389 | ENST00000354947 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000397997 | ENST00000422156 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000397997 | ENST00000540759 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000397997 | ENST00000550465 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
| In-frame | ENST00000397997 | ENST00000354947 | FRS2 | chr12 | 69962876 | + | PIP4K2C | chr12 | 57994107 | + |
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FusionProtFeatures for FRS2_PIP4K2C |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FRS2 | PIP4K2C |
| Adapter protein that links activated FGR and NGFreceptors to downstream signaling pathways. Plays an importantrole in the activation of MAP kinases and in the phosphorylationof PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1.Modulates signaling via SHC1 by competing for a common bindingsite on NTRK1. {ECO:0000269|PubMed:12974390,ECO:0000269|PubMed:21765395}. | May play an important role in the production ofPhosphatidylinositol bisphosphate (PIP2), in the endoplasmicreticulum. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >FRS2 | chr12:69962876 | chr12:57994107 | ENST00000299293 | + | 6 | 10 | 13_115 | 22 | 509 | Domain | IRS-type PTB |
| Hgene | >FRS2 | chr12:69962876 | chr12:57994107 | ENST00000397997 | + | 4 | 8 | 13_115 | 22 | 509 | Domain | IRS-type PTB |
| Hgene | >FRS2 | chr12:69962876 | chr12:57994107 | ENST00000549921 | + | 5 | 9 | 13_115 | 22 | 509 | Domain | IRS-type PTB |
| Hgene | >FRS2 | chr12:69962876 | chr12:57994107 | ENST00000550389 | + | 3 | 7 | 13_115 | 22 | 509 | Domain | IRS-type PTB |
| Tgene | PIP4K2C | chr12:69962876 | chr12:57994107 | ENST00000354947 | + | 5 | 10 | 43_420 | 233 | 422 | Domain | PIPK |
| Tgene | PIP4K2C | chr12:69962876 | chr12:57994107 | ENST00000422156 | + | 4 | 9 | 43_420 | 185 | 374 | Domain | PIPK |
| Tgene | PIP4K2C | chr12:69962876 | chr12:57994107 | ENST00000540759 | + | 5 | 11 | 43_420 | 233 | 831 | Domain | PIPK |
| Tgene | PIP4K2C | chr12:69962876 | chr12:57994107 | ENST00000550465 | + | 5 | 10 | 43_420 | 215 | 404 | Domain | PIPK |
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FusionGeneSequence for FRS2_PIP4K2C |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_211aa MGSCCSCPDKDTVPDNHRNKFKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAP VREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_633nt ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAG GATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAG TTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCC GTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGT ATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGA GCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACT GTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_1463nt AAAACCCTTCCCTCCCCCGCTCCCCCGGAAGTGCTTTTCCAAGATTCGGGCCGGAGAGAGGCCTTGTAGGCACAGCGGCTGAGACTCGAT CTGCTCCAAGTAGGGGCTCCAGCGCGGGTCGGAGTCTGGGGGTTCGCGCCCGCCGACCCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGA CGAAATGACCATTAAGAAGTAGATGCCCAGATGCAAAAGTGATGAAACAGTCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAA CCAGCTTGGAACAAAATTGTATCTGTTTTTCTCAGAAGAGAATTCCACAAGGAGATTTTCTTCTTTCTACCATCATCAAGATCAAGCAGG CAAGTTTACTTGCTGTCATCTTCTGCAAGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGC AGCAGAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAA GACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAA GTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTAC AGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGG GACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCC CTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGC CTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCT ACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTC AAGGTGGTGGGGTTCTGAGACACTTGGGGGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGCTGCAGG CTCCTTCCATCCAGATAACTCCATCCTGTCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCATTTTTC TTCCCTCTCTTCCTCCCCATGAGAAGTCTGCTTGTAGTATTAGAATGTTATTGTTGACTCTCTCCCAAGTGCCTTGATCTTTGTAATATC >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_2663nt AAAACCCTTCCCTCCCCCGCTCCCCCGGAAGTGCTTTTCCAAGATTCGGGCCGGAGAGAGGCCTTGTAGGCACAGCGGCTGAGACTCGAT CTGCTCCAAGTAGGGGCTCCAGCGCGGGTCGGAGTCTGGGGGTTCGCGCCCGCCGACCCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGA CGAAATGACCATTAAGAAGTAGATGCCCAGATGCAAAAGTGATGAAACAGTCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAA CCAGCTTGGAACAAAATTGTATCTGTTTTTCTCAGAAGAGAATTCCACAAGGAGATTTTCTTCTTTCTACCATCATCAAGATCAAGCAGG CAAGTTTACTTGCTGTCATCTTCTGCAAGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGC AGCAGAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAA GACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAA GTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTAC AGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGG GACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCC CTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGC CTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCT ACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTC AAGGAGCTAGGGGAAGGGGGTTGTTTGCCTTCTTCAGGACCTGACTGGACAGATGGACCTGGCTCAAGCAACTACTCTGGATGCACTTTG CTGTGTGGGATGAACTAAAAGTGTCTGAATTTTGCTGATAACTTTATAAAACTCACTATGGCATGCTTCCCTCCTGGTGGGCCCTAGGAT GGATGACACTCAAGATACTACAGATGTGGGTGCAGGCATGCACACACACGATGGAATATGGCCATTCCTACACAGGTGGGGTAGAGAGTG GGTCAGCAGCCTGGCACCTCACAGAGGTGGGACCTAAGAGGACTCATGATTATGCAGAGAATTGGATTGGGTCTCTGTCATAGATTGAGT AATCTCTTCCCTTACCTCAATTCCATCTCCACCCATCTCTACATCTGGGCACAGCAACCCAGAGATGGCCAAAAGCATTCAAGCCTGGGG GAAGATGTTTGACTATTGCTGCTCTTCACCAGAACCTCACACCTCTCCTGGGACTGGAACCCTTCAGTGGGTGTGTGGCCAGTTTTGGAG GCTGGAATGATGGGCCAGGGTGTAGGATTCATTCTCCATGTAAAGTTTCCTTTCATCCTGCCTAGCCATCCCCAAGGTTTATTTCCAGAA GAAAGGAATATCTCTACTTGGATCAATTCTGGTCATTTCAAGAGGATGGAGGCCTCAAGTGTGGGAACTTCCCCTACTCCCTGGATGTGT GTACCTAGCACACTTCCTTCTCCCACCCCTTTTTCCAGTTGGATTTGTTTTTCTGTTCTCTTCTGTCCTGTCTTATACTGCAACTGTGTC TCCTAGGGGACAGATGGCCTTCTTTGTCATCTTCACTCTCCACCCCCAGAGAGGAGTCAGAGCCATAACTCAATCACTCAGCCCCTCCAA AGATAGTTGATGTGTGATAATCTCATAATGTTGAGAACCCTGATGAGATACATTGTCTTCCTCTCCCTACAATGCCTCTGGGGCCAAGGC ACCCATTCTTCTTGCTATCCTCCATCCCCCTTGAGGCTTCCACTTTTTTTTTTTTTAGACATAAAGCTGGGCATCAGCAACTGGCCTGTG GTGATGCAAAGCTGCTTTGCTCTGTATCTGGCTGGACTGATCTGTCTCACAAGAAGCCATGAGGCCATAGGGAGAAGCTCCCTCTCCCCT TCATCTTCTGCTCCAAAGGTGGTAGCAAGAGGAGTACCCAGTTAGGGGTTGGAGCCCCCATATAACATCTTCCTGTCAGAAGACTGATGG ATCTTTTTCATTCCAACCATCTCCCTTTCCCCCGATGAATGCAATAAAACTCTGTGACACCAGCAACCATTGCTCTTTAGAAATGGGTTT TCTGATCATATGGCTGATGTGTTATGGGCAGTATGGATGTCTTCATTTGTTGCTTCTGTTTTTCATCTTTTTTGTTTTATTAATAAAAAT >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_1416nt AAAACCCTTCCCTCCCCCGCTCCCCCGGAAGTGCTTTTCCAAGATTCGGGCCGGAGAGAGGCCTTGTAGGCACAGCGGCTGAGACTCGAT CTGCTCCAAGTAGGGGCTCCAGCGCGGGTCGGAGTCTGGGGGTTCGCGCCCGCCGACCCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGA CGAAATGACCATTAAGAAGTAGATGCCCAGATGCAAAAGTGATGAAACAGTCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAA CCAGCTTGGAACAAAATTGTATCTGTTTTTCTCAGAAGAGAATTCCACAAGGAGATTTTCTTCTTTCTACCATCATCAAGATCAAGCAGG CAAGTTTACTTGCTGTCATCTTCTGCAAGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGC AGCAGAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAA GACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAA GTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTAC AGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGG GACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCC CTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGC CTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCT ACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTC AAGGTGGTGGGGTTCTGAGACACTTGGGGGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGCTGCAGG CTCCTTCCATCCAGATAACTCCATCCTGTCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCATTTTTC >In-frame_FRS2_ENST00000299293_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_2785nt AAAACCCTTCCCTCCCCCGCTCCCCCGGAAGTGCTTTTCCAAGATTCGGGCCGGAGAGAGGCCTTGTAGGCACAGCGGCTGAGACTCGAT CTGCTCCAAGTAGGGGCTCCAGCGCGGGTCGGAGTCTGGGGGTTCGCGCCCGCCGACCCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGA CGAAATGACCATTAAGAAGTAGATGCCCAGATGCAAAAGTGATGAAACAGTCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAA CCAGCTTGGAACAAAATTGTATCTGTTTTTCTCAGAAGAGAATTCCACAAGGAGATTTTCTTCTTTCTACCATCATCAAGATCAAGCAGG CAAGTTTACTTGCTGTCATCTTCTGCAAGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGC AGCAGAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAA GACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAA GTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTAC AGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGG GACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCC CTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGC CTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCT ACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTC AAGGTGGTGGGGTTCTGAGACACTTGGGGGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGCTGCAGG CTCCTTCCATCCAGATAACTCCATCCTGTCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCATTTTTC TTCCCTCTCTTCCTCCCCATGAGAAGTCTGCTTGTAGTATTAGAATGTTATTGTTGACTCTCTCCCAAGTGCCTTGATCTTTGTAATATC TCCTGTTGTTTCTATGATATAGGAGCTAGGGGAAGGGGGTTGTTTGCCTTCTTCAGGACCTGACTGGACAGATGGACCTGGCTCAAGCAA CTACTCTGGATGCACTTTGCTGTGTGGGATGAACTAAAAGTGTCTGAATTTTGCTGATAACTTTATAAAACTCACTATGGCATGCTTCCC TCCTGGTGGGCCCTAGGATGGATGACACTCAAGATACTACAGATGTGGGTGCAGGCATGCACACACACGATGGAATATGGCCATTCCTAC ACAGGTGGGGTAGAGAGTGGGTCAGCAGCCTGGCACCTCACAGAGGTGGGACCTAAGAGGACTCATGATTATGCAGAGAATTGGATTGGG TCTCTGTCATAGATTGAGTAATCTCTTCCCTTACCTCAATTCCATCTCCACCCATCTCTACATCTGGGCACAGCAACCCAGAGATGGCCA AAAGCATTCAAGCCTGGGGGAAGATGTTTGACTATTGCTGCTCTTCACCAGAACCTCACACCTCTCCTGGGACTGGAACCCTTCAGTGGG TGTGTGGCCAGTTTTGGAGGCTGGAATGATGGGCCAGGGTGTAGGATTCATTCTCCATGTAAAGTTTCCTTTCATCCTGCCTAGCCATCC CCAAGGTTTATTTCCAGAAGAAAGGAATATCTCTACTTGGATCAATTCTGGTCATTTCAAGAGGATGGAGGCCTCAAGTGTGGGAACTTC CCCTACTCCCTGGATGTGTGTACCTAGCACACTTCCTTCTCCCACCCCTTTTTCCAGTTGGATTTGTTTTTCTGTTCTCTTCTGTCCTGT CTTATACTGCAACTGTGTCTCCTAGGGGACAGATGGCCTTCTTTGTCATCTTCACTCTCCACCCCCAGAGAGGAGTCAGAGCCATAACTC AATCACTCAGCCCCTCCAAAGATAGTTGATGTGTGATAATCTCATAATGTTGAGAACCCTGATGAGATACATTGTCTTCCTCTCCCTACA ATGCCTCTGGGGCCAAGGCACCCATTCTTCTTGCTATCCTCCATCCCCCTTGAGGCTTCCACTTTTTTTTTTTTTAGACATAAAGCTGGG CATCAGCAACTGGCCTGTGGTGATGCAAAGCTGCTTTGCTCTGTATCTGGCTGGACTGATCTGTCTCACAAGAAGCCATGAGGCCATAGG GAGAAGCTCCCTCTCCCCTTCATCTTCTGCTCCAAAGGTGGTAGCAAGAGGAGTACCCAGTTAGGGGTTGGAGCCCCCATATAACATCTT >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_1369nt GGAAGTGCTTTTCCAAGATTCGGGCCGGAGAGAGGCCTTGTAGGCACAGCGGCTGAGACTCGATCTGCTCCAAGTAGGGGCTCCAGCGCG GGTCGGAGTCTGGGGGTTCGCGCCCGCCGACCCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGACGAAATGACCATTAAGAAGTAGATGC CCAGATGCAAAAGTGATGAAACAGTCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAACCAGCTTGGAACAAAATTGTATCTGT TTTTCTCAGAAGAGAATTCCACAAGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGCAGCA GAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACA CTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAAGTAT ATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTACAGCC TTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGGGACT GCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCCCTGG GCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCA TTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCTACTG TCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTCAAGG TGGTGGGGTTCTGAGACACTTGGGGGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGCTGCAGGCTCC TTCCATCCAGATAACTCCATCCTGTCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCATTTTTCTTCC CTCTCTTCCTCCCCATGAGAAGTCTGCTTGTAGTATTAGAATGTTATTGTTGACTCTCTCCCAAGTGCCTTGATCTTTGTAATATCTCCT >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_2569nt GGAAGTGCTTTTCCAAGATTCGGGCCGGAGAGAGGCCTTGTAGGCACAGCGGCTGAGACTCGATCTGCTCCAAGTAGGGGCTCCAGCGCG GGTCGGAGTCTGGGGGTTCGCGCCCGCCGACCCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGACGAAATGACCATTAAGAAGTAGATGC CCAGATGCAAAAGTGATGAAACAGTCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAACCAGCTTGGAACAAAATTGTATCTGT TTTTCTCAGAAGAGAATTCCACAAGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGCAGCA GAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACA CTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAAGTAT ATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTACAGCC TTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGGGACT GCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCCCTGG GCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCA TTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCTACTG TCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTCAAGG AGCTAGGGGAAGGGGGTTGTTTGCCTTCTTCAGGACCTGACTGGACAGATGGACCTGGCTCAAGCAACTACTCTGGATGCACTTTGCTGT GTGGGATGAACTAAAAGTGTCTGAATTTTGCTGATAACTTTATAAAACTCACTATGGCATGCTTCCCTCCTGGTGGGCCCTAGGATGGAT GACACTCAAGATACTACAGATGTGGGTGCAGGCATGCACACACACGATGGAATATGGCCATTCCTACACAGGTGGGGTAGAGAGTGGGTC AGCAGCCTGGCACCTCACAGAGGTGGGACCTAAGAGGACTCATGATTATGCAGAGAATTGGATTGGGTCTCTGTCATAGATTGAGTAATC TCTTCCCTTACCTCAATTCCATCTCCACCCATCTCTACATCTGGGCACAGCAACCCAGAGATGGCCAAAAGCATTCAAGCCTGGGGGAAG ATGTTTGACTATTGCTGCTCTTCACCAGAACCTCACACCTCTCCTGGGACTGGAACCCTTCAGTGGGTGTGTGGCCAGTTTTGGAGGCTG GAATGATGGGCCAGGGTGTAGGATTCATTCTCCATGTAAAGTTTCCTTTCATCCTGCCTAGCCATCCCCAAGGTTTATTTCCAGAAGAAA GGAATATCTCTACTTGGATCAATTCTGGTCATTTCAAGAGGATGGAGGCCTCAAGTGTGGGAACTTCCCCTACTCCCTGGATGTGTGTAC CTAGCACACTTCCTTCTCCCACCCCTTTTTCCAGTTGGATTTGTTTTTCTGTTCTCTTCTGTCCTGTCTTATACTGCAACTGTGTCTCCT AGGGGACAGATGGCCTTCTTTGTCATCTTCACTCTCCACCCCCAGAGAGGAGTCAGAGCCATAACTCAATCACTCAGCCCCTCCAAAGAT AGTTGATGTGTGATAATCTCATAATGTTGAGAACCCTGATGAGATACATTGTCTTCCTCTCCCTACAATGCCTCTGGGGCCAAGGCACCC ATTCTTCTTGCTATCCTCCATCCCCCTTGAGGCTTCCACTTTTTTTTTTTTTAGACATAAAGCTGGGCATCAGCAACTGGCCTGTGGTGA TGCAAAGCTGCTTTGCTCTGTATCTGGCTGGACTGATCTGTCTCACAAGAAGCCATGAGGCCATAGGGAGAAGCTCCCTCTCCCCTTCAT CTTCTGCTCCAAAGGTGGTAGCAAGAGGAGTACCCAGTTAGGGGTTGGAGCCCCCATATAACATCTTCCTGTCAGAAGACTGATGGATCT TTTTCATTCCAACCATCTCCCTTTCCCCCGATGAATGCAATAAAACTCTGTGACACCAGCAACCATTGCTCTTTAGAAATGGGTTTTCTG ATCATATGGCTGATGTGTTATGGGCAGTATGGATGTCTTCATTTGTTGCTTCTGTTTTTCATCTTTTTTGTTTTATTAATAAAAATTTAT >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_1322nt GGAAGTGCTTTTCCAAGATTCGGGCCGGAGAGAGGCCTTGTAGGCACAGCGGCTGAGACTCGATCTGCTCCAAGTAGGGGCTCCAGCGCG GGTCGGAGTCTGGGGGTTCGCGCCCGCCGACCCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGACGAAATGACCATTAAGAAGTAGATGC CCAGATGCAAAAGTGATGAAACAGTCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAACCAGCTTGGAACAAAATTGTATCTGT TTTTCTCAGAAGAGAATTCCACAAGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGCAGCA GAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACA CTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAAGTAT ATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTACAGCC TTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGGGACT GCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCCCTGG GCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCA TTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCTACTG TCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTCAAGG TGGTGGGGTTCTGAGACACTTGGGGGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGCTGCAGGCTCC TTCCATCCAGATAACTCCATCCTGTCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCATTTTTCTTCC >In-frame_FRS2_ENST00000549921_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_2691nt GGAAGTGCTTTTCCAAGATTCGGGCCGGAGAGAGGCCTTGTAGGCACAGCGGCTGAGACTCGATCTGCTCCAAGTAGGGGCTCCAGCGCG GGTCGGAGTCTGGGGGTTCGCGCCCGCCGACCCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGACGAAATGACCATTAAGAAGTAGATGC CCAGATGCAAAAGTGATGAAACAGTCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAACCAGCTTGGAACAAAATTGTATCTGT TTTTCTCAGAAGAGAATTCCACAAGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGCAGCA GAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACA CTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAAGTAT ATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTACAGCC TTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGGGACT GCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCCCTGG GCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCA TTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCTACTG TCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTCAAGG TGGTGGGGTTCTGAGACACTTGGGGGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGCTGCAGGCTCC TTCCATCCAGATAACTCCATCCTGTCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCATTTTTCTTCC CTCTCTTCCTCCCCATGAGAAGTCTGCTTGTAGTATTAGAATGTTATTGTTGACTCTCTCCCAAGTGCCTTGATCTTTGTAATATCTCCT GTTGTTTCTATGATATAGGAGCTAGGGGAAGGGGGTTGTTTGCCTTCTTCAGGACCTGACTGGACAGATGGACCTGGCTCAAGCAACTAC TCTGGATGCACTTTGCTGTGTGGGATGAACTAAAAGTGTCTGAATTTTGCTGATAACTTTATAAAACTCACTATGGCATGCTTCCCTCCT GGTGGGCCCTAGGATGGATGACACTCAAGATACTACAGATGTGGGTGCAGGCATGCACACACACGATGGAATATGGCCATTCCTACACAG GTGGGGTAGAGAGTGGGTCAGCAGCCTGGCACCTCACAGAGGTGGGACCTAAGAGGACTCATGATTATGCAGAGAATTGGATTGGGTCTC TGTCATAGATTGAGTAATCTCTTCCCTTACCTCAATTCCATCTCCACCCATCTCTACATCTGGGCACAGCAACCCAGAGATGGCCAAAAG CATTCAAGCCTGGGGGAAGATGTTTGACTATTGCTGCTCTTCACCAGAACCTCACACCTCTCCTGGGACTGGAACCCTTCAGTGGGTGTG TGGCCAGTTTTGGAGGCTGGAATGATGGGCCAGGGTGTAGGATTCATTCTCCATGTAAAGTTTCCTTTCATCCTGCCTAGCCATCCCCAA GGTTTATTTCCAGAAGAAAGGAATATCTCTACTTGGATCAATTCTGGTCATTTCAAGAGGATGGAGGCCTCAAGTGTGGGAACTTCCCCT ACTCCCTGGATGTGTGTACCTAGCACACTTCCTTCTCCCACCCCTTTTTCCAGTTGGATTTGTTTTTCTGTTCTCTTCTGTCCTGTCTTA TACTGCAACTGTGTCTCCTAGGGGACAGATGGCCTTCTTTGTCATCTTCACTCTCCACCCCCAGAGAGGAGTCAGAGCCATAACTCAATC ACTCAGCCCCTCCAAAGATAGTTGATGTGTGATAATCTCATAATGTTGAGAACCCTGATGAGATACATTGTCTTCCTCTCCCTACAATGC CTCTGGGGCCAAGGCACCCATTCTTCTTGCTATCCTCCATCCCCCTTGAGGCTTCCACTTTTTTTTTTTTTAGACATAAAGCTGGGCATC AGCAACTGGCCTGTGGTGATGCAAAGCTGCTTTGCTCTGTATCTGGCTGGACTGATCTGTCTCACAAGAAGCCATGAGGCCATAGGGAGA AGCTCCCTCTCCCCTTCATCTTCTGCTCCAAAGGTGGTAGCAAGAGGAGTACCCAGTTAGGGGTTGGAGCCCCCATATAACATCTTCCTG >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_1199nt GAGGCCTTGTAGGCACAGCGGCTGAGACTCGATCTGCTCCAAGTAGGGGCTCCAGCGCGGGTCGGAGTCTGGGGGTTCGCGCCCGCCGAC CCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGACGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGA TGCTGCAGCAGAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCA GATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAAC CAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATG GACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTG GATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCAT CGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTC ATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAG ATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTG ATGTTCAAGGTGGTGGGGTTCTGAGACACTTGGGGGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGC TGCAGGCTCCTTCCATCCAGATAACTCCATCCTGTCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCA TTTTTCTTCCCTCTCTTCCTCCCCATGAGAAGTCTGCTTGTAGTATTAGAATGTTATTGTTGACTCTCTCCCAAGTGCCTTGATCTTTGT >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_2399nt GAGGCCTTGTAGGCACAGCGGCTGAGACTCGATCTGCTCCAAGTAGGGGCTCCAGCGCGGGTCGGAGTCTGGGGGTTCGCGCCCGCCGAC CCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGACGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGA TGCTGCAGCAGAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCA GATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAAC CAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATG GACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTG GATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCAT CGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTC ATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAG ATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTG ATGTTCAAGGAGCTAGGGGAAGGGGGTTGTTTGCCTTCTTCAGGACCTGACTGGACAGATGGACCTGGCTCAAGCAACTACTCTGGATGC ACTTTGCTGTGTGGGATGAACTAAAAGTGTCTGAATTTTGCTGATAACTTTATAAAACTCACTATGGCATGCTTCCCTCCTGGTGGGCCC TAGGATGGATGACACTCAAGATACTACAGATGTGGGTGCAGGCATGCACACACACGATGGAATATGGCCATTCCTACACAGGTGGGGTAG AGAGTGGGTCAGCAGCCTGGCACCTCACAGAGGTGGGACCTAAGAGGACTCATGATTATGCAGAGAATTGGATTGGGTCTCTGTCATAGA TTGAGTAATCTCTTCCCTTACCTCAATTCCATCTCCACCCATCTCTACATCTGGGCACAGCAACCCAGAGATGGCCAAAAGCATTCAAGC CTGGGGGAAGATGTTTGACTATTGCTGCTCTTCACCAGAACCTCACACCTCTCCTGGGACTGGAACCCTTCAGTGGGTGTGTGGCCAGTT TTGGAGGCTGGAATGATGGGCCAGGGTGTAGGATTCATTCTCCATGTAAAGTTTCCTTTCATCCTGCCTAGCCATCCCCAAGGTTTATTT CCAGAAGAAAGGAATATCTCTACTTGGATCAATTCTGGTCATTTCAAGAGGATGGAGGCCTCAAGTGTGGGAACTTCCCCTACTCCCTGG ATGTGTGTACCTAGCACACTTCCTTCTCCCACCCCTTTTTCCAGTTGGATTTGTTTTTCTGTTCTCTTCTGTCCTGTCTTATACTGCAAC TGTGTCTCCTAGGGGACAGATGGCCTTCTTTGTCATCTTCACTCTCCACCCCCAGAGAGGAGTCAGAGCCATAACTCAATCACTCAGCCC CTCCAAAGATAGTTGATGTGTGATAATCTCATAATGTTGAGAACCCTGATGAGATACATTGTCTTCCTCTCCCTACAATGCCTCTGGGGC CAAGGCACCCATTCTTCTTGCTATCCTCCATCCCCCTTGAGGCTTCCACTTTTTTTTTTTTTAGACATAAAGCTGGGCATCAGCAACTGG CCTGTGGTGATGCAAAGCTGCTTTGCTCTGTATCTGGCTGGACTGATCTGTCTCACAAGAAGCCATGAGGCCATAGGGAGAAGCTCCCTC TCCCCTTCATCTTCTGCTCCAAAGGTGGTAGCAAGAGGAGTACCCAGTTAGGGGTTGGAGCCCCCATATAACATCTTCCTGTCAGAAGAC TGATGGATCTTTTTCATTCCAACCATCTCCCTTTCCCCCGATGAATGCAATAAAACTCTGTGACACCAGCAACCATTGCTCTTTAGAAAT GGGTTTTCTGATCATATGGCTGATGTGTTATGGGCAGTATGGATGTCTTCATTTGTTGCTTCTGTTTTTCATCTTTTTTGTTTTATTAAT >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_1152nt GAGGCCTTGTAGGCACAGCGGCTGAGACTCGATCTGCTCCAAGTAGGGGCTCCAGCGCGGGTCGGAGTCTGGGGGTTCGCGCCCGCCGAC CCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGACGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGA TGCTGCAGCAGAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCA GATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAAC CAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATG GACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTG GATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCAT CGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTC ATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAG ATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTG ATGTTCAAGGTGGTGGGGTTCTGAGACACTTGGGGGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGC TGCAGGCTCCTTCCATCCAGATAACTCCATCCTGTCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCA >In-frame_FRS2_ENST00000550389_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_2521nt GAGGCCTTGTAGGCACAGCGGCTGAGACTCGATCTGCTCCAAGTAGGGGCTCCAGCGCGGGTCGGAGTCTGGGGGTTCGCGCCCGCCGAC CCGCGCCCTGCTCCCTCTCAGCACCTGGGCGGACGGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGA TGCTGCAGCAGAGGCTAAGAATATTAATGGCCAGATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCA GATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAAC CAGAAAGTATATATTGGTGAAGAGGAGAAGAAAATATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATG GACTACAGCCTTCTGCTAGGCATCCACGACATCATTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTG GATGGGGACTGCAGCCTGACTGGACCTCCTGCTCTTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCAT CGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCATTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTC ATGGGCCTCATTGATATCCTTACACAGTATGATGCTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAG ATCTCTACTGTCCATCCGGAGCAGTATGCTAAGCGATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTG ATGTTCAAGGTGGTGGGGTTCTGAGACACTTGGGGGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGC TGCAGGCTCCTTCCATCCAGATAACTCCATCCTGTCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCA TTTTTCTTCCCTCTCTTCCTCCCCATGAGAAGTCTGCTTGTAGTATTAGAATGTTATTGTTGACTCTCTCCCAAGTGCCTTGATCTTTGT AATATCTCCTGTTGTTTCTATGATATAGGAGCTAGGGGAAGGGGGTTGTTTGCCTTCTTCAGGACCTGACTGGACAGATGGACCTGGCTC AAGCAACTACTCTGGATGCACTTTGCTGTGTGGGATGAACTAAAAGTGTCTGAATTTTGCTGATAACTTTATAAAACTCACTATGGCATG CTTCCCTCCTGGTGGGCCCTAGGATGGATGACACTCAAGATACTACAGATGTGGGTGCAGGCATGCACACACACGATGGAATATGGCCAT TCCTACACAGGTGGGGTAGAGAGTGGGTCAGCAGCCTGGCACCTCACAGAGGTGGGACCTAAGAGGACTCATGATTATGCAGAGAATTGG ATTGGGTCTCTGTCATAGATTGAGTAATCTCTTCCCTTACCTCAATTCCATCTCCACCCATCTCTACATCTGGGCACAGCAACCCAGAGA TGGCCAAAAGCATTCAAGCCTGGGGGAAGATGTTTGACTATTGCTGCTCTTCACCAGAACCTCACACCTCTCCTGGGACTGGAACCCTTC AGTGGGTGTGTGGCCAGTTTTGGAGGCTGGAATGATGGGCCAGGGTGTAGGATTCATTCTCCATGTAAAGTTTCCTTTCATCCTGCCTAG CCATCCCCAAGGTTTATTTCCAGAAGAAAGGAATATCTCTACTTGGATCAATTCTGGTCATTTCAAGAGGATGGAGGCCTCAAGTGTGGG AACTTCCCCTACTCCCTGGATGTGTGTACCTAGCACACTTCCTTCTCCCACCCCTTTTTCCAGTTGGATTTGTTTTTCTGTTCTCTTCTG TCCTGTCTTATACTGCAACTGTGTCTCCTAGGGGACAGATGGCCTTCTTTGTCATCTTCACTCTCCACCCCCAGAGAGGAGTCAGAGCCA TAACTCAATCACTCAGCCCCTCCAAAGATAGTTGATGTGTGATAATCTCATAATGTTGAGAACCCTGATGAGATACATTGTCTTCCTCTC CCTACAATGCCTCTGGGGCCAAGGCACCCATTCTTCTTGCTATCCTCCATCCCCCTTGAGGCTTCCACTTTTTTTTTTTTTAGACATAAA GCTGGGCATCAGCAACTGGCCTGTGGTGATGCAAAGCTGCTTTGCTCTGTATCTGGCTGGACTGATCTGTCTCACAAGAAGCCATGAGGC CATAGGGAGAAGCTCCCTCTCCCCTTCATCTTCTGCTCCAAAGGTGGTAGCAAGAGGAGTACCCAGTTAGGGGTTGGAGCCCCCATATAA CATCTTCCTGTCAGAAGACTGATGGATCTTTTTCATTCCAACCATCTCCCTTTCCCCCGATGAATGCAATAAAACTCTGTGACACCAGCA >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000422156_chr12_57994107_+_1255nt TATTCAAGAGTAACATTCTTAATAACTTAACCTATATTTCAGAAATGACCATTAAGAAGTAGATGCCCAGATGCAAAAGTGATGAAACAG TCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAACCAGCTTGGAACAAAATTGTATCTGTTTTTCTCAGAAGAGAATTCCACAA GGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGCAGCAGAGGCTAAGAATATTAATGGCCAG ATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACA AGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAA TATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCA TTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTC TTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCA TTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATG CTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGC GATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTCAAGGTGGTGGGGTTCTGAGACACTTGGG GGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGCTGCAGGCTCCTTCCATCCAGATAACTCCATCCTG TCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCATTTTTCTTCCCTCTCTTCCTCCCCATGAGAAGTC >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000540759_chr12_57994107_+_2455nt TATTCAAGAGTAACATTCTTAATAACTTAACCTATATTTCAGAAATGACCATTAAGAAGTAGATGCCCAGATGCAAAAGTGATGAAACAG TCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAACCAGCTTGGAACAAAATTGTATCTGTTTTTCTCAGAAGAGAATTCCACAA GGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGCAGCAGAGGCTAAGAATATTAATGGCCAG ATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACA AGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAA TATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCA TTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTC TTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCA TTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATG CTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGC GATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTCAAGGAGCTAGGGGAAGGGGGTTGTTTGC CTTCTTCAGGACCTGACTGGACAGATGGACCTGGCTCAAGCAACTACTCTGGATGCACTTTGCTGTGTGGGATGAACTAAAAGTGTCTGA ATTTTGCTGATAACTTTATAAAACTCACTATGGCATGCTTCCCTCCTGGTGGGCCCTAGGATGGATGACACTCAAGATACTACAGATGTG GGTGCAGGCATGCACACACACGATGGAATATGGCCATTCCTACACAGGTGGGGTAGAGAGTGGGTCAGCAGCCTGGCACCTCACAGAGGT GGGACCTAAGAGGACTCATGATTATGCAGAGAATTGGATTGGGTCTCTGTCATAGATTGAGTAATCTCTTCCCTTACCTCAATTCCATCT CCACCCATCTCTACATCTGGGCACAGCAACCCAGAGATGGCCAAAAGCATTCAAGCCTGGGGGAAGATGTTTGACTATTGCTGCTCTTCA CCAGAACCTCACACCTCTCCTGGGACTGGAACCCTTCAGTGGGTGTGTGGCCAGTTTTGGAGGCTGGAATGATGGGCCAGGGTGTAGGAT TCATTCTCCATGTAAAGTTTCCTTTCATCCTGCCTAGCCATCCCCAAGGTTTATTTCCAGAAGAAAGGAATATCTCTACTTGGATCAATT CTGGTCATTTCAAGAGGATGGAGGCCTCAAGTGTGGGAACTTCCCCTACTCCCTGGATGTGTGTACCTAGCACACTTCCTTCTCCCACCC CTTTTTCCAGTTGGATTTGTTTTTCTGTTCTCTTCTGTCCTGTCTTATACTGCAACTGTGTCTCCTAGGGGACAGATGGCCTTCTTTGTC ATCTTCACTCTCCACCCCCAGAGAGGAGTCAGAGCCATAACTCAATCACTCAGCCCCTCCAAAGATAGTTGATGTGTGATAATCTCATAA TGTTGAGAACCCTGATGAGATACATTGTCTTCCTCTCCCTACAATGCCTCTGGGGCCAAGGCACCCATTCTTCTTGCTATCCTCCATCCC CCTTGAGGCTTCCACTTTTTTTTTTTTTAGACATAAAGCTGGGCATCAGCAACTGGCCTGTGGTGATGCAAAGCTGCTTTGCTCTGTATC TGGCTGGACTGATCTGTCTCACAAGAAGCCATGAGGCCATAGGGAGAAGCTCCCTCTCCCCTTCATCTTCTGCTCCAAAGGTGGTAGCAA GAGGAGTACCCAGTTAGGGGTTGGAGCCCCCATATAACATCTTCCTGTCAGAAGACTGATGGATCTTTTTCATTCCAACCATCTCCCTTT CCCCCGATGAATGCAATAAAACTCTGTGACACCAGCAACCATTGCTCTTTAGAAATGGGTTTTCTGATCATATGGCTGATGTGTTATGGG CAGTATGGATGTCTTCATTTGTTGCTTCTGTTTTTCATCTTTTTTGTTTTATTAATAAAAATTTATGTATTTGCTCCTGTTACTATAATA >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000550465_chr12_57994107_+_1208nt TATTCAAGAGTAACATTCTTAATAACTTAACCTATATTTCAGAAATGACCATTAAGAAGTAGATGCCCAGATGCAAAAGTGATGAAACAG TCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAACCAGCTTGGAACAAAATTGTATCTGTTTTTCTCAGAAGAGAATTCCACAA GGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGCAGCAGAGGCTAAGAATATTAATGGCCAG ATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACA AGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAA TATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCA TTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTC TTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCA TTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATG CTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGC GATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTCAAGGTGGTGGGGTTCTGAGACACTTGGG GGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGCTGCAGGCTCCTTCCATCCAGATAACTCCATCCTG TCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCATTTTTCTTCCCTCTCTTCCTCCCCATGAGAAGTC >In-frame_FRS2_ENST00000397997_chr12_69962876_+_PIP4K2C_ENST00000354947_chr12_57994107_+_2577nt TATTCAAGAGTAACATTCTTAATAACTTAACCTATATTTCAGAAATGACCATTAAGAAGTAGATGCCCAGATGCAAAAGTGATGAAACAG TCCATTTGTCATAAAGTAAGATGCAGCTGTGGCATGTCAACCAGCTTGGAACAAAATTGTATCTGTTTTTCTCAGAAGAGAATTCCACAA GGTTAAATCAGCAAACAAAGAAAACATGGTATTTTGAAATATGATTAAACTCCTGATGCTGCAGCAGAGGCTAAGAATATTAATGGCCAG ATCTAGTGCACACATGGTCTTCTGAAGAAGCCATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACA AGTTTAAGGTTAAAGAATTGCCCACCCTTAAGGATATGGACTTTCTCAACAAGAACCAGAAAGTATATATTGGTGAAGAGGAGAAGAAAA TATTTCTGGAGAAGCTGAAGAGAGATGTGGAGTTTCTAGTGCAGCTGAAGATCATGGACTACAGCCTTCTGCTAGGCATCCACGACATCA TTCGGGGCTCTGAACCAGAGGAGGAAGCGCCCGTGCGGGAGGATGAGTCAGAGGTGGATGGGGACTGCAGCCTGACTGGACCTCCTGCTC TTGTGGGCTCCTATGGCACCTCCCCAGAGGGTATCGGAGGCTACATCCATTCCCATCGGCCCCTGGGCCCAGGAGAGTTTGAGTCCTTCA TTGATGTCTATGCCATCCGGAGTGCTGAAGGAGCCCCCCAGAAGGAGGTCTACTTCATGGGCCTCATTGATATCCTTACACAGTATGATG CTAAGAAGAAAGCAGCTCATGCAGCCAAAACTGTCAAGCATGGGGCTGGGGCAGAGATCTCTACTGTCCATCCGGAGCAGTATGCTAAGC GATTCCTGGATTTTATTACCAACATCTTTGCCTAAGAGACTGCCTGGTTCTCTCTGATGTTCAAGGTGGTGGGGTTCTGAGACACTTGGG GGAATTGTGGGGATATTCTAGCCACCAGTTCTCTTCTTCCTTTGCTAAATTCAGGCTGCAGGCTCCTTCCATCCAGATAACTCCATCCTG TCGAGTAGGCTCTTTCTGACCCTCAGAAATACATTGTCCTTTTTCCTCTTTGCCCATTTTTCTTCCCTCTCTTCCTCCCCATGAGAAGTC TGCTTGTAGTATTAGAATGTTATTGTTGACTCTCTCCCAAGTGCCTTGATCTTTGTAATATCTCCTGTTGTTTCTATGATATAGGAGCTA GGGGAAGGGGGTTGTTTGCCTTCTTCAGGACCTGACTGGACAGATGGACCTGGCTCAAGCAACTACTCTGGATGCACTTTGCTGTGTGGG ATGAACTAAAAGTGTCTGAATTTTGCTGATAACTTTATAAAACTCACTATGGCATGCTTCCCTCCTGGTGGGCCCTAGGATGGATGACAC TCAAGATACTACAGATGTGGGTGCAGGCATGCACACACACGATGGAATATGGCCATTCCTACACAGGTGGGGTAGAGAGTGGGTCAGCAG CCTGGCACCTCACAGAGGTGGGACCTAAGAGGACTCATGATTATGCAGAGAATTGGATTGGGTCTCTGTCATAGATTGAGTAATCTCTTC CCTTACCTCAATTCCATCTCCACCCATCTCTACATCTGGGCACAGCAACCCAGAGATGGCCAAAAGCATTCAAGCCTGGGGGAAGATGTT TGACTATTGCTGCTCTTCACCAGAACCTCACACCTCTCCTGGGACTGGAACCCTTCAGTGGGTGTGTGGCCAGTTTTGGAGGCTGGAATG ATGGGCCAGGGTGTAGGATTCATTCTCCATGTAAAGTTTCCTTTCATCCTGCCTAGCCATCCCCAAGGTTTATTTCCAGAAGAAAGGAAT ATCTCTACTTGGATCAATTCTGGTCATTTCAAGAGGATGGAGGCCTCAAGTGTGGGAACTTCCCCTACTCCCTGGATGTGTGTACCTAGC ACACTTCCTTCTCCCACCCCTTTTTCCAGTTGGATTTGTTTTTCTGTTCTCTTCTGTCCTGTCTTATACTGCAACTGTGTCTCCTAGGGG ACAGATGGCCTTCTTTGTCATCTTCACTCTCCACCCCCAGAGAGGAGTCAGAGCCATAACTCAATCACTCAGCCCCTCCAAAGATAGTTG ATGTGTGATAATCTCATAATGTTGAGAACCCTGATGAGATACATTGTCTTCCTCTCCCTACAATGCCTCTGGGGCCAAGGCACCCATTCT TCTTGCTATCCTCCATCCCCCTTGAGGCTTCCACTTTTTTTTTTTTTAGACATAAAGCTGGGCATCAGCAACTGGCCTGTGGTGATGCAA AGCTGCTTTGCTCTGTATCTGGCTGGACTGATCTGTCTCACAAGAAGCCATGAGGCCATAGGGAGAAGCTCCCTCTCCCCTTCATCTTCT GCTCCAAAGGTGGTAGCAAGAGGAGTACCCAGTTAGGGGTTGGAGCCCCCATATAACATCTTCCTGTCAGAAGACTGATGGATCTTTTTC |
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FusionGenePPI for FRS2_PIP4K2C |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FRS2 | PTPN11, INSR, SOS1, GRB2, CBL, FGFR1, CRK, NTRK1, NTRK2, NTRK3, RET, PRKCI, FGFR2, FLOT1, SORBS1, SPRY2, LYN, BECN1, RPS6, TMEM17, GAB1, GAB2, CDH1, TRIM25 | PIP4K2C | ELAVL1, APP, PIP4K2C, FBXO25, CSNK2A2, ARL6IP4, EAF1, LZTS2, ZRANB2, EPB41L3, CSNK2A1, CSNK2B, DDX23, MTPN, MYL9, NCAPD3, PRPF8, SKP1, MED4, NF2, PIP4K2A, ARHGAP22, AHCYL2, GPBP1L1, PRICKLE3, HIF1AN, TULP3, ZNF428, CAMKV, POC1B, SUN2, TNFRSF19, C16orf71, GSPT2, APBA3, TNFRSF1A, HSD17B10 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FRS2_PIP4K2C |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FRS2_PIP4K2C |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PIP4K2C | C0036341 | Schizophrenia | 2 | PSYGENET |
| Tgene | PIP4K2C | C0005586 | Bipolar Disorder | 1 | PSYGENET |
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