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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 13843

FusionGeneSummary for FOXP1_SH3RF2

check button Fusion gene summary
Fusion gene informationFusion gene name: FOXP1_SH3RF2
Fusion gene ID: 13843
HgeneTgene
Gene symbol

FOXP1

SH3RF2

Gene ID

27086

153769

Gene nameforkhead box P1SH3 domain containing ring finger 2
Synonyms12CC4|HSPC215|MFH|QRF1|hFKH1BHEPP1|POSHER|PPP1R39|RNF158
Cytomap

3p13

5q32

Type of geneprotein-codingprotein-coding
Descriptionforkhead box protein P1fork head-related protein like Bglutamine-rich factor 1mac-1-regulated forkheadputative E3 ubiquitin-protein ligase SH3RF2POSH-eliminating RING proteinRING finger protein 158RING-type E3 ubiquitin transferase SH3RF2SH3 domain-containing RING finger protein 2heart protein phosphatase 1-binding proteinphosphatase 1 binding prote
Modification date2018052220180523
UniProtAcc

Q9H334

Q8TEC5

Ensembl transtripts involved in fusion geneENST00000318789, ENST00000475937, 
ENST00000493089, ENST00000484350, 
ENST00000318779, ENST00000491238, 
ENST00000498215, ENST00000468577, 
ENST00000472382, 
ENST00000359120, 
ENST00000511217, ENST00000511705, 
Fusion gene scores* DoF score21 X 13 X 11=30031 X 1 X 1=1
# samples 261
** MAII scorelog2(26/3003*10)=-3.52982094652869
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(1/1*10)=3.32192809488736
Context

PubMed: FOXP1 [Title/Abstract] AND SH3RF2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
Tumor suppressor gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFOXP1

GO:0002903

negative regulation of B cell apoptotic process

25267198

HgeneFOXP1

GO:0030316

osteoclast differentiation

18799727

HgeneFOXP1

GO:0032496

response to lipopolysaccharide

18799727

HgeneFOXP1

GO:0032680

regulation of tumor necrosis factor production

18799727

HgeneFOXP1

GO:0035926

chemokine (C-C motif) ligand 2 secretion

18799727

HgeneFOXP1

GO:0036035

osteoclast development

18799727

HgeneFOXP1

GO:0042116

macrophage activation

18799727

HgeneFOXP1

GO:0042117

monocyte activation

18799727

HgeneFOXP1

GO:0045655

regulation of monocyte differentiation

15286807

HgeneFOXP1

GO:0045892

negative regulation of transcription, DNA-templated

20950788

HgeneFOXP1

GO:0050706

regulation of interleukin-1 beta secretion

18799727

HgeneFOXP1

GO:0050727

regulation of inflammatory response

18799727

HgeneFOXP1

GO:0060766

negative regulation of androgen receptor signaling pathway

18640093

HgeneFOXP1

GO:1900424

regulation of defense response to bacterium

18799727

HgeneFOXP1

GO:1901256

regulation of macrophage colony-stimulating factor production

18799727

HgeneFOXP1

GO:2001182

regulation of interleukin-12 secretion

18799727

TgeneSH3RF2

GO:0010923

negative regulation of phosphatase activity

19389623


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVCHOLTCGA-WD-A7RX-01AFOXP1chr3

71090479

-SH3RF2chr5

145379621

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000318789ENST00000359120FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
In-frameENST00000318789ENST00000511217FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
5CDS-intronENST00000318789ENST00000511705FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
Frame-shitENST00000475937ENST00000359120FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
Frame-shitENST00000475937ENST00000511217FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
5CDS-intronENST00000475937ENST00000511705FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
In-frameENST00000493089ENST00000359120FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
In-frameENST00000493089ENST00000511217FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
5CDS-intronENST00000493089ENST00000511705FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
Frame-shitENST00000484350ENST00000359120FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
Frame-shitENST00000484350ENST00000511217FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
5CDS-intronENST00000484350ENST00000511705FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
intron-3CDSENST00000318779ENST00000359120FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
intron-3CDSENST00000318779ENST00000511217FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
intron-intronENST00000318779ENST00000511705FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
Frame-shitENST00000491238ENST00000359120FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
Frame-shitENST00000491238ENST00000511217FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
5CDS-intronENST00000491238ENST00000511705FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
Frame-shitENST00000498215ENST00000359120FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
Frame-shitENST00000498215ENST00000511217FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
5CDS-intronENST00000498215ENST00000511705FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
Frame-shitENST00000468577ENST00000359120FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
Frame-shitENST00000468577ENST00000511217FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
5CDS-intronENST00000468577ENST00000511705FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
5UTR-3CDSENST00000472382ENST00000359120FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
5UTR-3CDSENST00000472382ENST00000511217FOXP1chr3

71090479

-SH3RF2chr5

145379621

+
5UTR-intronENST00000472382ENST00000511705FOXP1chr3

71090479

-SH3RF2chr5

145379621

+

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FusionProtFeatures for FOXP1_SH3RF2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FOXP1

Q9H334

SH3RF2

Q8TEC5

Has E3 ubiquitin-protein ligase activity(PubMed:24130170). Acts as an anti-apoptotic regulator of the JNKpathway by ubiquitinating and promoting the degradation of SH3RF1,a scaffold protein that is required for pro-apoptotic JNKactivation (PubMed:22128169). Facilitates TNF-alpha-mediatedrecruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A andregulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation (PubMed:24130170). InhibitsPPP1CA phosphatase activity (PubMed:19945436, PubMed:19389623).{ECO:0000269|PubMed:19389623, ECO:0000269|PubMed:19945436,ECO:0000269|PubMed:22128169, ECO:0000269|PubMed:24130170}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFOXP1chr3:71090479chr5:145379621ENST00000318789-112155_230289678Compositional biasNote=Gln-rich
HgeneFOXP1chr3:71090479chr5:145379621ENST00000475937-102055_230289678Compositional biasNote=Gln-rich
HgeneFOXP1chr3:71090479chr5:145379621ENST00000493089-112155_230289677Compositional biasNote=Gln-rich
HgeneFOXP1chr3:71090479chr5:145379621ENST00000498215-71755_230289678Compositional biasNote=Gln-rich
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000359120+110125_184126730DomainSH3 1
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000359120+110187_252126730DomainSH3 2
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000359120+110380_441126730DomainSH3 3
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000511217+010125_1841261697DomainSH3 1
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000511217+010187_2521261697DomainSH3 2
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000511217+010380_4411261697DomainSH3 3

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFOXP1chr3:71090479chr5:145379621ENST00000318779-1755_230-159115Compositional biasNote=Gln-rich
HgeneFOXP1chr3:71090479chr5:145379621ENST00000484350-61655_230213602Compositional biasNote=Gln-rich
HgeneFOXP1chr3:71090479chr5:145379621ENST00000318779-17465_555-159115DNA bindingFork-head
HgeneFOXP1chr3:71090479chr5:145379621ENST00000318789-1121465_555289678DNA bindingFork-head
HgeneFOXP1chr3:71090479chr5:145379621ENST00000475937-1020465_555289678DNA bindingFork-head
HgeneFOXP1chr3:71090479chr5:145379621ENST00000484350-616465_555213602DNA bindingFork-head
HgeneFOXP1chr3:71090479chr5:145379621ENST00000493089-1121465_555289677DNA bindingFork-head
HgeneFOXP1chr3:71090479chr5:145379621ENST00000498215-717465_555289678DNA bindingFork-head
HgeneFOXP1chr3:71090479chr5:145379621ENST00000318779-17348_369-159115RegionNote=Leucine-zipper
HgeneFOXP1chr3:71090479chr5:145379621ENST00000318779-17382_386-159115RegionCTBP1-binding
HgeneFOXP1chr3:71090479chr5:145379621ENST00000318789-1121348_369289678RegionNote=Leucine-zipper
HgeneFOXP1chr3:71090479chr5:145379621ENST00000318789-1121382_386289678RegionCTBP1-binding
HgeneFOXP1chr3:71090479chr5:145379621ENST00000475937-1020348_369289678RegionNote=Leucine-zipper
HgeneFOXP1chr3:71090479chr5:145379621ENST00000475937-1020382_386289678RegionCTBP1-binding
HgeneFOXP1chr3:71090479chr5:145379621ENST00000484350-616348_369213602RegionNote=Leucine-zipper
HgeneFOXP1chr3:71090479chr5:145379621ENST00000484350-616382_386213602RegionCTBP1-binding
HgeneFOXP1chr3:71090479chr5:145379621ENST00000493089-1121348_369289677RegionNote=Leucine-zipper
HgeneFOXP1chr3:71090479chr5:145379621ENST00000493089-1121382_386289677RegionCTBP1-binding
HgeneFOXP1chr3:71090479chr5:145379621ENST00000498215-717348_369289678RegionNote=Leucine-zipper
HgeneFOXP1chr3:71090479chr5:145379621ENST00000498215-717382_386289678RegionCTBP1-binding
HgeneFOXP1chr3:71090479chr5:145379621ENST00000318779-17306_331-159115Zinc fingerNote=C2H2-type
HgeneFOXP1chr3:71090479chr5:145379621ENST00000318789-1121306_331289678Zinc fingerNote=C2H2-type
HgeneFOXP1chr3:71090479chr5:145379621ENST00000475937-1020306_331289678Zinc fingerNote=C2H2-type
HgeneFOXP1chr3:71090479chr5:145379621ENST00000484350-616306_331213602Zinc fingerNote=C2H2-type
HgeneFOXP1chr3:71090479chr5:145379621ENST00000493089-1121306_331289677Zinc fingerNote=C2H2-type
HgeneFOXP1chr3:71090479chr5:145379621ENST00000498215-717306_331289678Zinc fingerNote=C2H2-type
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000359120+11012_53126730Zinc fingerRING-type
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000511217+01012_531261697Zinc fingerRING-type


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FusionGeneSequence for FOXP1_SH3RF2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_FOXP1_ENST00000318789_chr3_71090479_-_SH3RF2_ENST00000359120_chr5_145379621_+_893aa
MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQALQVARQLLLQQQQQQQVSGLKSPKRNDKQ
PALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFTKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLA
FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLI
MNPHASTNGQLSVHTPKRERCLEQRPTATTEGRIPVT_GLIREISSFSGDSLMRIGTRGKSMASAGTSQPAPWKSSSSCPSRPRSAGPST
TSTYEARTRVRTRIA_PSSRTISSL_SAEWMRTGQKAS_EIK_ASSLSCL_SQTSPQDTF_RRTKVASHPAQKTCPWCPRPPEATRLPSV
GAQGPGGRCLGSFPSQQP_TLSTGWSILLQGAIW_RSAPQCSSAPATPL_SPSPWRKQTFLPAVWDRSALITPHLSLQDIPQPWSVCLAP
SNTSQRTCL_PCTPTQPMDPMSWTCKREKASGSWGSARTAGSGASPWSPGESASSQTITSSPFSERPLVFQTPGALVSTPHGRTPPPLCP
PKAAFQKVIHGKAVPSNPSLCPLP_STP_EAQPALGL_DKGLFGKGGAA_ERMDPCRDPSSPGSPLSW_APSDAAPPWSFGLSSSNSTSH
RGSPPPPQPWWWRWGPSLPSRGSPPSRASAGAVRPGSTPRPAPSLWKTKKSPSRVSLCQNRPHLPHHPSW_NQKTQEMASKSKSKP_DFR

>In-frame_FOXP1_ENST00000318789_chr3_71090479_-_SH3RF2_ENST00000511217_chr5_145379621_+_893aa
MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQALQVARQLLLQQQQQQQVSGLKSPKRNDKQ
PALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFTKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLA
FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLI
MNPHASTNGQLSVHTPKRERCLEQRPTATTEGRIPVT_GLIREISSFSGDSLMRIGTRGKSMASAGTSQPAPWKSSSSCPSRPRSAGPST
TSTYEARTRVRTRIA_PSSRTISSL_SAEWMRTGQKAS_EIK_ASSLSCL_SQTSPQDTF_RRTKVASHPAQKTCPWCPRPPEATRLPSV
GAQGPGGRCLGSFPSQQP_TLSTGWSILLQGAIW_RSAPQCSSAPATPL_SPSPWRKQTFLPAVWDRSALITPHLSLQDIPQPWSVCLAP
SNTSQRTCL_PCTPTQPMDPMSWTCKREKASGSWGSARTAGSGASPWSPGESASSQTITSSPFSERPLVFQTPGALVSTPHGRTPPPLCP
PKAAFQKVIHGKAVPSNPSLCPLP_STP_EAQPALGL_DKGLFGKGGAA_ERMDPCRDPSSPGSPLSW_APSDAAPPWSFGLSSSNSTSH
RGSPPPPQPWWWRWGPSLPSRGSPPSRASAGAVRPGSTPRPAPSLWKTKKSPSRVSLCQNRPHLPHHPSW_NQKTQEMASKSKSKP_DFR

>In-frame_FOXP1_ENST00000493089_chr3_71090479_-_SH3RF2_ENST00000359120_chr5_145379621_+_893aa
MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQALQVARQLLLQQQQQQQVSGLKSPKRNDKQ
PALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFTKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLA
FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLI
MNPHASTNGQLSVHTPKRERCLEQRPTATTEGRIPVT_GLIREISSFSGDSLMRIGTRGKSMASAGTSQPAPWKSSSSCPSRPRSAGPST
TSTYEARTRVRTRIA_PSSRTISSL_SAEWMRTGQKAS_EIK_ASSLSCL_SQTSPQDTF_RRTKVASHPAQKTCPWCPRPPEATRLPSV
GAQGPGGRCLGSFPSQQP_TLSTGWSILLQGAIW_RSAPQCSSAPATPL_SPSPWRKQTFLPAVWDRSALITPHLSLQDIPQPWSVCLAP
SNTSQRTCL_PCTPTQPMDPMSWTCKREKASGSWGSARTAGSGASPWSPGESASSQTITSSPFSERPLVFQTPGALVSTPHGRTPPPLCP
PKAAFQKVIHGKAVPSNPSLCPLP_STP_EAQPALGL_DKGLFGKGGAA_ERMDPCRDPSSPGSPLSW_APSDAAPPWSFGLSSSNSTSH
RGSPPPPQPWWWRWGPSLPSRGSPPSRASAGAVRPGSTPRPAPSLWKTKKSPSRVSLCQNRPHLPHHPSW_NQKTQEMASKSKSKP_DFR

>In-frame_FOXP1_ENST00000493089_chr3_71090479_-_SH3RF2_ENST00000511217_chr5_145379621_+_893aa
MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQALQVARQLLLQQQQQQQVSGLKSPKRNDKQ
PALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFTKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLA
FQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLI
MNPHASTNGQLSVHTPKRERCLEQRPTATTEGRIPVT_GLIREISSFSGDSLMRIGTRGKSMASAGTSQPAPWKSSSSCPSRPRSAGPST
TSTYEARTRVRTRIA_PSSRTISSL_SAEWMRTGQKAS_EIK_ASSLSCL_SQTSPQDTF_RRTKVASHPAQKTCPWCPRPPEATRLPSV
GAQGPGGRCLGSFPSQQP_TLSTGWSILLQGAIW_RSAPQCSSAPATPL_SPSPWRKQTFLPAVWDRSALITPHLSLQDIPQPWSVCLAP
SNTSQRTCL_PCTPTQPMDPMSWTCKREKASGSWGSARTAGSGASPWSPGESASSQTITSSPFSERPLVFQTPGALVSTPHGRTPPPLCP
PKAAFQKVIHGKAVPSNPSLCPLP_STP_EAQPALGL_DKGLFGKGGAA_ERMDPCRDPSSPGSPLSW_APSDAAPPWSFGLSSSNSTSH
RGSPPPPQPWWWRWGPSLPSRGSPPSRASAGAVRPGSTPRPAPSLWKTKKSPSRVSLCQNRPHLPHHPSW_NQKTQEMASKSKSKP_DFR


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_FOXP1_ENST00000318789_chr3_71090479_-_SH3RF2_ENST00000359120_chr5_145379621_+_2681nt
ATGATGCAAGAATCTGGGACTGAGACAAAAAGTAACGGTTCAGCCATCCAGAATGGGTCGGGCGGCAGCAACCACTTACTAGAGTGCGGC
GGTCTTCGGGAGGGGCGGTCCAACGGAGAGACGCCGGCCGTGGACATCGGGGCAGCTGACCTCGCCCACGCCCAGCAGCAGCAGCAACAG
GCACTTCAGGTGGCAAGACAGCTCCTTCTTCAGCAGCAACAGCAGCAGCAAGTTAGTGGATTAAAATCTCCCAAGAGGAATGACAAACAA
CCAGCTCTTCAGGTTCCCGTGTCAGTGGCTATGATGACACCTCAAGTTATCACTCCCCAGCAAATGCAGCAGATCCTCCAGCAACAAGTG
CTGAGCCCTCAGCAGCTCCAGGTTCTCCTCCAGCAGCAGCAGGCCCTCATGCTTCAACAGCAGCAGCTTCAAGAGTTTTATAAAAAACAA
CAGGAACAGTTGCAGCTTCAACTTTTACAACAACAACATGCTGGAAAACAGCCTAAAGAGCAACAGCAGGTGGCTACCCAGCAGTTGGCT
TTTCAGCAGCAGCTTTTACAGATGCAGCAGTTACAGCAGCAGCACCTCCTGTCTTTGCAGCGCCAAGGCCTTCTGACAATTCAGCCCGGG
CAGCCTGCCCTTCCCCTTCAACCTCTTGCTCAAGGCATGATTCCAACAGAACTGCAGCAGCTCTGGAAAGAAGTGACAAGTGCTCATACT
GCAGAAGAAACCACAGGCAACAATCACAGCAGTTTGGATCTGACCACGACATGTGTCTCCTCCTCTGCACCTTCCAAGACCTCCTTAATA
ATGAACCCACATGCCTCTACCAATGGACAGCTCTCAGTCCACACTCCCAAAAGGGAAAGGTGCCTCGAGCAAAGGCCTTATGCAACTACA
GAGGGCAGAATCCCGGTGACCTAAGGTTTAATAAGGGAGATATCATCCTTCTCCGGAGACAGCTTGATGAGAATTGGTACCAGGGGGAAA
TCAATGGCATCAGCGGGAACTTCCCAGCCAGCTCCGTGGAAGTCATCAAGCAGCTGCCCCAGCCGCCCCCGCTCTGCAGGGCCCTCTACA
ACTTCGACCTACGAGGCAAGGACAAGAGTGAGAACCAGGATTGCCTGACCTTCCTCAAGGACGATATCATCACTGTGATCAGCCGAGTGG
ATGAGAACTGGGCAGAAGGCAAGTTAGGAGATAAAGTAGGCATCTTCCCTATCTTGTTTGTAGAGCCAAACCTCACCGCAAGACACCTTT
TAGAGAAGAACAAAGGTCGCCAGTCATCCCGCACAAAAAACCTGTCCCTGGTGTCCTCGTCCTCCAGAGGCAACACGTCTACCCTCCGTA
GGGGCCCAGGGTCCAGGAGGAAGGTGCCTGGGCAGTTTTCCATCACAACAGCCTTGAACACTCTCAACCGGATGGTCCATTCTCCTTCAG
GGCGCCATATGGTAGAGATCAGCACCCCAGTGCTCATCAGCTCCAGCAACCCCTCTGTGATCACCCAGCCCATGGAGAAAGCAGACGTTC
CTTCCAGCTGTGTGGGACAGGTCAGCACTTATCACCCCGCACCTGTCTCTCCAGGACATTCCACAGCCGTGGTCAGTCTGCCTGGCTCCC
AGCAACACCTCTCAGCGAACATGTTTGTAGCCCTGCACTCCTACTCAGCCCATGGACCCGATGAGCTGGACCTGCAAAAGGGAGAAGGCG
TCAGGGTCCTGGGGAAGTGCCAGGACGGCTGGCTCAGGGGCGTCTCCTTGGTCACCGGGCGAGTCGGCATCTTCCCAAACAATTACGTCA
TCCCCATTTTCAGAAAGACCTCTAGTTTTCCAGACTCCCGGAGCCCTGGTCTCTACACCACATGGACGTTATCCACCTCCTCTGTGTCCT
CCCAAGGCAGCATTTCAGAAGGTGATCCACGGCAAAGCCGTCCCTTCAAATCCGTCTTTGTGCCCACTGCCATAGTCAACCCCGTGAGAA
GCACAGCCGGCCCTGGGACTTTAGGACAAGGGTCTCTTCGGAAAGGGCGGAGCAGCATGAGAAAGAATGGATCCCTGCAGAGACCCCTCC
AGTCCGGGATCCCCACTCTCGTGGTAGGCTCCCTCAGACGCAGCCCCACCATGGTCCTTCGGCCTCAGCAGTTCCAATTCTACCAGCCAC
AGGGGATCCCCTCCTCCCCCTCAGCCGTGGTGGTGGAGATGGGGTCCAAGCCTGCCCTCACGGGGGAGCCCGCCCTCACGTGCATCAGCA
GGGGCAGTGAGGCCTGGATCCACTCCGCGGCCAGCTCCCTCATTATGGAAGACAAAGAAATCCCCATCAAGAGTGAGCCTCTGCCAAAAC
CGCCCGCATCTGCCCCACCATCCATCCTGGTGAAACCAGAAAACTCAAGAAATGGCATCGAAAAGCAAGTCAAAACCGTGAGATTTCAGA
ATTACAGCCCTCCTCCCACCAAACATTACACCTCCCATCCCACCTCCGGAAAGCCTGAACAGCCAGCCACCCTCAAGGCGTCCCAGCCTG
AAGCAGCGTCCTTGGGCCCAGAGATGACCGTCCTATTTGCCCACCGAAGTGGCTGCCACTCCGGACAGCAGACAGACCTCCGGAGAAAGT

>In-frame_FOXP1_ENST00000318789_chr3_71090479_-_SH3RF2_ENST00000511217_chr5_145379621_+_2681nt
ATGATGCAAGAATCTGGGACTGAGACAAAAAGTAACGGTTCAGCCATCCAGAATGGGTCGGGCGGCAGCAACCACTTACTAGAGTGCGGC
GGTCTTCGGGAGGGGCGGTCCAACGGAGAGACGCCGGCCGTGGACATCGGGGCAGCTGACCTCGCCCACGCCCAGCAGCAGCAGCAACAG
GCACTTCAGGTGGCAAGACAGCTCCTTCTTCAGCAGCAACAGCAGCAGCAAGTTAGTGGATTAAAATCTCCCAAGAGGAATGACAAACAA
CCAGCTCTTCAGGTTCCCGTGTCAGTGGCTATGATGACACCTCAAGTTATCACTCCCCAGCAAATGCAGCAGATCCTCCAGCAACAAGTG
CTGAGCCCTCAGCAGCTCCAGGTTCTCCTCCAGCAGCAGCAGGCCCTCATGCTTCAACAGCAGCAGCTTCAAGAGTTTTATAAAAAACAA
CAGGAACAGTTGCAGCTTCAACTTTTACAACAACAACATGCTGGAAAACAGCCTAAAGAGCAACAGCAGGTGGCTACCCAGCAGTTGGCT
TTTCAGCAGCAGCTTTTACAGATGCAGCAGTTACAGCAGCAGCACCTCCTGTCTTTGCAGCGCCAAGGCCTTCTGACAATTCAGCCCGGG
CAGCCTGCCCTTCCCCTTCAACCTCTTGCTCAAGGCATGATTCCAACAGAACTGCAGCAGCTCTGGAAAGAAGTGACAAGTGCTCATACT
GCAGAAGAAACCACAGGCAACAATCACAGCAGTTTGGATCTGACCACGACATGTGTCTCCTCCTCTGCACCTTCCAAGACCTCCTTAATA
ATGAACCCACATGCCTCTACCAATGGACAGCTCTCAGTCCACACTCCCAAAAGGGAAAGGTGCCTCGAGCAAAGGCCTTATGCAACTACA
GAGGGCAGAATCCCGGTGACCTAAGGTTTAATAAGGGAGATATCATCCTTCTCCGGAGACAGCTTGATGAGAATTGGTACCAGGGGGAAA
TCAATGGCATCAGCGGGAACTTCCCAGCCAGCTCCGTGGAAGTCATCAAGCAGCTGCCCCAGCCGCCCCCGCTCTGCAGGGCCCTCTACA
ACTTCGACCTACGAGGCAAGGACAAGAGTGAGAACCAGGATTGCCTGACCTTCCTCAAGGACGATATCATCACTGTGATCAGCCGAGTGG
ATGAGAACTGGGCAGAAGGCAAGTTAGGAGATAAAGTAGGCATCTTCCCTATCTTGTTTGTAGAGCCAAACCTCACCGCAAGACACCTTT
TAGAGAAGAACAAAGGTCGCCAGTCATCCCGCACAAAAAACCTGTCCCTGGTGTCCTCGTCCTCCAGAGGCAACACGTCTACCCTCCGTA
GGGGCCCAGGGTCCAGGAGGAAGGTGCCTGGGCAGTTTTCCATCACAACAGCCTTGAACACTCTCAACCGGATGGTCCATTCTCCTTCAG
GGCGCCATATGGTAGAGATCAGCACCCCAGTGCTCATCAGCTCCAGCAACCCCTCTGTGATCACCCAGCCCATGGAGAAAGCAGACGTTC
CTTCCAGCTGTGTGGGACAGGTCAGCACTTATCACCCCGCACCTGTCTCTCCAGGACATTCCACAGCCGTGGTCAGTCTGCCTGGCTCCC
AGCAACACCTCTCAGCGAACATGTTTGTAGCCCTGCACTCCTACTCAGCCCATGGACCCGATGAGCTGGACCTGCAAAAGGGAGAAGGCG
TCAGGGTCCTGGGGAAGTGCCAGGACGGCTGGCTCAGGGGCGTCTCCTTGGTCACCGGGCGAGTCGGCATCTTCCCAAACAATTACGTCA
TCCCCATTTTCAGAAAGACCTCTAGTTTTCCAGACTCCCGGAGCCCTGGTCTCTACACCACATGGACGTTATCCACCTCCTCTGTGTCCT
CCCAAGGCAGCATTTCAGAAGGTGATCCACGGCAAAGCCGTCCCTTCAAATCCGTCTTTGTGCCCACTGCCATAGTCAACCCCGTGAGAA
GCACAGCCGGCCCTGGGACTTTAGGACAAGGGTCTCTTCGGAAAGGGCGGAGCAGCATGAGAAAGAATGGATCCCTGCAGAGACCCCTCC
AGTCCGGGATCCCCACTCTCGTGGTAGGCTCCCTCAGACGCAGCCCCACCATGGTCCTTCGGCCTCAGCAGTTCCAATTCTACCAGCCAC
AGGGGATCCCCTCCTCCCCCTCAGCCGTGGTGGTGGAGATGGGGTCCAAGCCTGCCCTCACGGGGGAGCCCGCCCTCACGTGCATCAGCA
GGGGCAGTGAGGCCTGGATCCACTCCGCGGCCAGCTCCCTCATTATGGAAGACAAAGAAATCCCCATCAAGAGTGAGCCTCTGCCAAAAC
CGCCCGCATCTGCCCCACCATCCATCCTGGTGAAACCAGAAAACTCAAGAAATGGCATCGAAAAGCAAGTCAAAACCGTGAGATTTCAGA
ATTACAGCCCTCCTCCCACCAAACATTACACCTCCCATCCCACCTCCGGAAAGCCTGAACAGCCAGCCACCCTCAAGGCGTCCCAGCCTG
AAGCAGCGTCCTTGGGCCCAGAGATGACCGTCCTATTTGCCCACCGAAGTGGCTGCCACTCCGGACAGCAGACAGACCTCCGGAGAAAGT

>In-frame_FOXP1_ENST00000493089_chr3_71090479_-_SH3RF2_ENST00000359120_chr5_145379621_+_2681nt
ATGATGCAAGAATCTGGGACTGAGACAAAAAGTAACGGTTCAGCCATCCAGAATGGGTCGGGCGGCAGCAACCACTTACTAGAGTGCGGC
GGTCTTCGGGAGGGGCGGTCCAACGGAGAGACGCCGGCCGTGGACATCGGGGCAGCTGACCTCGCCCACGCCCAGCAGCAGCAGCAACAG
GCACTTCAGGTGGCAAGACAGCTCCTTCTTCAGCAGCAACAGCAGCAGCAAGTTAGTGGATTAAAATCTCCCAAGAGGAATGACAAACAA
CCAGCTCTTCAGGTTCCCGTGTCAGTGGCTATGATGACACCTCAAGTTATCACTCCCCAGCAAATGCAGCAGATCCTCCAGCAACAAGTG
CTGAGCCCTCAGCAGCTCCAGGTTCTCCTCCAGCAGCAGCAGGCCCTCATGCTTCAACAGCAGCAGCTTCAAGAGTTTTATAAAAAACAA
CAGGAACAGTTGCAGCTTCAACTTTTACAACAACAACATGCTGGAAAACAGCCTAAAGAGCAACAGCAGGTGGCTACCCAGCAGTTGGCT
TTTCAGCAGCAGCTTTTACAGATGCAGCAGTTACAGCAGCAGCACCTCCTGTCTTTGCAGCGCCAAGGCCTTCTGACAATTCAGCCCGGG
CAGCCTGCCCTTCCCCTTCAACCTCTTGCTCAAGGCATGATTCCAACAGAACTGCAGCAGCTCTGGAAAGAAGTGACAAGTGCTCATACT
GCAGAAGAAACCACAGGCAACAATCACAGCAGTTTGGATCTGACCACGACATGTGTCTCCTCCTCTGCACCTTCCAAGACCTCCTTAATA
ATGAACCCACATGCCTCTACCAATGGACAGCTCTCAGTCCACACTCCCAAAAGGGAAAGGTGCCTCGAGCAAAGGCCTTATGCAACTACA
GAGGGCAGAATCCCGGTGACCTAAGGTTTAATAAGGGAGATATCATCCTTCTCCGGAGACAGCTTGATGAGAATTGGTACCAGGGGGAAA
TCAATGGCATCAGCGGGAACTTCCCAGCCAGCTCCGTGGAAGTCATCAAGCAGCTGCCCCAGCCGCCCCCGCTCTGCAGGGCCCTCTACA
ACTTCGACCTACGAGGCAAGGACAAGAGTGAGAACCAGGATTGCCTGACCTTCCTCAAGGACGATATCATCACTGTGATCAGCCGAGTGG
ATGAGAACTGGGCAGAAGGCAAGTTAGGAGATAAAGTAGGCATCTTCCCTATCTTGTTTGTAGAGCCAAACCTCACCGCAAGACACCTTT
TAGAGAAGAACAAAGGTCGCCAGTCATCCCGCACAAAAAACCTGTCCCTGGTGTCCTCGTCCTCCAGAGGCAACACGTCTACCCTCCGTA
GGGGCCCAGGGTCCAGGAGGAAGGTGCCTGGGCAGTTTTCCATCACAACAGCCTTGAACACTCTCAACCGGATGGTCCATTCTCCTTCAG
GGCGCCATATGGTAGAGATCAGCACCCCAGTGCTCATCAGCTCCAGCAACCCCTCTGTGATCACCCAGCCCATGGAGAAAGCAGACGTTC
CTTCCAGCTGTGTGGGACAGGTCAGCACTTATCACCCCGCACCTGTCTCTCCAGGACATTCCACAGCCGTGGTCAGTCTGCCTGGCTCCC
AGCAACACCTCTCAGCGAACATGTTTGTAGCCCTGCACTCCTACTCAGCCCATGGACCCGATGAGCTGGACCTGCAAAAGGGAGAAGGCG
TCAGGGTCCTGGGGAAGTGCCAGGACGGCTGGCTCAGGGGCGTCTCCTTGGTCACCGGGCGAGTCGGCATCTTCCCAAACAATTACGTCA
TCCCCATTTTCAGAAAGACCTCTAGTTTTCCAGACTCCCGGAGCCCTGGTCTCTACACCACATGGACGTTATCCACCTCCTCTGTGTCCT
CCCAAGGCAGCATTTCAGAAGGTGATCCACGGCAAAGCCGTCCCTTCAAATCCGTCTTTGTGCCCACTGCCATAGTCAACCCCGTGAGAA
GCACAGCCGGCCCTGGGACTTTAGGACAAGGGTCTCTTCGGAAAGGGCGGAGCAGCATGAGAAAGAATGGATCCCTGCAGAGACCCCTCC
AGTCCGGGATCCCCACTCTCGTGGTAGGCTCCCTCAGACGCAGCCCCACCATGGTCCTTCGGCCTCAGCAGTTCCAATTCTACCAGCCAC
AGGGGATCCCCTCCTCCCCCTCAGCCGTGGTGGTGGAGATGGGGTCCAAGCCTGCCCTCACGGGGGAGCCCGCCCTCACGTGCATCAGCA
GGGGCAGTGAGGCCTGGATCCACTCCGCGGCCAGCTCCCTCATTATGGAAGACAAAGAAATCCCCATCAAGAGTGAGCCTCTGCCAAAAC
CGCCCGCATCTGCCCCACCATCCATCCTGGTGAAACCAGAAAACTCAAGAAATGGCATCGAAAAGCAAGTCAAAACCGTGAGATTTCAGA
ATTACAGCCCTCCTCCCACCAAACATTACACCTCCCATCCCACCTCCGGAAAGCCTGAACAGCCAGCCACCCTCAAGGCGTCCCAGCCTG
AAGCAGCGTCCTTGGGCCCAGAGATGACCGTCCTATTTGCCCACCGAAGTGGCTGCCACTCCGGACAGCAGACAGACCTCCGGAGAAAGT

>In-frame_FOXP1_ENST00000493089_chr3_71090479_-_SH3RF2_ENST00000511217_chr5_145379621_+_2681nt
ATGATGCAAGAATCTGGGACTGAGACAAAAAGTAACGGTTCAGCCATCCAGAATGGGTCGGGCGGCAGCAACCACTTACTAGAGTGCGGC
GGTCTTCGGGAGGGGCGGTCCAACGGAGAGACGCCGGCCGTGGACATCGGGGCAGCTGACCTCGCCCACGCCCAGCAGCAGCAGCAACAG
GCACTTCAGGTGGCAAGACAGCTCCTTCTTCAGCAGCAACAGCAGCAGCAAGTTAGTGGATTAAAATCTCCCAAGAGGAATGACAAACAA
CCAGCTCTTCAGGTTCCCGTGTCAGTGGCTATGATGACACCTCAAGTTATCACTCCCCAGCAAATGCAGCAGATCCTCCAGCAACAAGTG
CTGAGCCCTCAGCAGCTCCAGGTTCTCCTCCAGCAGCAGCAGGCCCTCATGCTTCAACAGCAGCAGCTTCAAGAGTTTTATAAAAAACAA
CAGGAACAGTTGCAGCTTCAACTTTTACAACAACAACATGCTGGAAAACAGCCTAAAGAGCAACAGCAGGTGGCTACCCAGCAGTTGGCT
TTTCAGCAGCAGCTTTTACAGATGCAGCAGTTACAGCAGCAGCACCTCCTGTCTTTGCAGCGCCAAGGCCTTCTGACAATTCAGCCCGGG
CAGCCTGCCCTTCCCCTTCAACCTCTTGCTCAAGGCATGATTCCAACAGAACTGCAGCAGCTCTGGAAAGAAGTGACAAGTGCTCATACT
GCAGAAGAAACCACAGGCAACAATCACAGCAGTTTGGATCTGACCACGACATGTGTCTCCTCCTCTGCACCTTCCAAGACCTCCTTAATA
ATGAACCCACATGCCTCTACCAATGGACAGCTCTCAGTCCACACTCCCAAAAGGGAAAGGTGCCTCGAGCAAAGGCCTTATGCAACTACA
GAGGGCAGAATCCCGGTGACCTAAGGTTTAATAAGGGAGATATCATCCTTCTCCGGAGACAGCTTGATGAGAATTGGTACCAGGGGGAAA
TCAATGGCATCAGCGGGAACTTCCCAGCCAGCTCCGTGGAAGTCATCAAGCAGCTGCCCCAGCCGCCCCCGCTCTGCAGGGCCCTCTACA
ACTTCGACCTACGAGGCAAGGACAAGAGTGAGAACCAGGATTGCCTGACCTTCCTCAAGGACGATATCATCACTGTGATCAGCCGAGTGG
ATGAGAACTGGGCAGAAGGCAAGTTAGGAGATAAAGTAGGCATCTTCCCTATCTTGTTTGTAGAGCCAAACCTCACCGCAAGACACCTTT
TAGAGAAGAACAAAGGTCGCCAGTCATCCCGCACAAAAAACCTGTCCCTGGTGTCCTCGTCCTCCAGAGGCAACACGTCTACCCTCCGTA
GGGGCCCAGGGTCCAGGAGGAAGGTGCCTGGGCAGTTTTCCATCACAACAGCCTTGAACACTCTCAACCGGATGGTCCATTCTCCTTCAG
GGCGCCATATGGTAGAGATCAGCACCCCAGTGCTCATCAGCTCCAGCAACCCCTCTGTGATCACCCAGCCCATGGAGAAAGCAGACGTTC
CTTCCAGCTGTGTGGGACAGGTCAGCACTTATCACCCCGCACCTGTCTCTCCAGGACATTCCACAGCCGTGGTCAGTCTGCCTGGCTCCC
AGCAACACCTCTCAGCGAACATGTTTGTAGCCCTGCACTCCTACTCAGCCCATGGACCCGATGAGCTGGACCTGCAAAAGGGAGAAGGCG
TCAGGGTCCTGGGGAAGTGCCAGGACGGCTGGCTCAGGGGCGTCTCCTTGGTCACCGGGCGAGTCGGCATCTTCCCAAACAATTACGTCA
TCCCCATTTTCAGAAAGACCTCTAGTTTTCCAGACTCCCGGAGCCCTGGTCTCTACACCACATGGACGTTATCCACCTCCTCTGTGTCCT
CCCAAGGCAGCATTTCAGAAGGTGATCCACGGCAAAGCCGTCCCTTCAAATCCGTCTTTGTGCCCACTGCCATAGTCAACCCCGTGAGAA
GCACAGCCGGCCCTGGGACTTTAGGACAAGGGTCTCTTCGGAAAGGGCGGAGCAGCATGAGAAAGAATGGATCCCTGCAGAGACCCCTCC
AGTCCGGGATCCCCACTCTCGTGGTAGGCTCCCTCAGACGCAGCCCCACCATGGTCCTTCGGCCTCAGCAGTTCCAATTCTACCAGCCAC
AGGGGATCCCCTCCTCCCCCTCAGCCGTGGTGGTGGAGATGGGGTCCAAGCCTGCCCTCACGGGGGAGCCCGCCCTCACGTGCATCAGCA
GGGGCAGTGAGGCCTGGATCCACTCCGCGGCCAGCTCCCTCATTATGGAAGACAAAGAAATCCCCATCAAGAGTGAGCCTCTGCCAAAAC
CGCCCGCATCTGCCCCACCATCCATCCTGGTGAAACCAGAAAACTCAAGAAATGGCATCGAAAAGCAAGTCAAAACCGTGAGATTTCAGA
ATTACAGCCCTCCTCCCACCAAACATTACACCTCCCATCCCACCTCCGGAAAGCCTGAACAGCCAGCCACCCTCAAGGCGTCCCAGCCTG
AAGCAGCGTCCTTGGGCCCAGAGATGACCGTCCTATTTGCCCACCGAAGTGGCTGCCACTCCGGACAGCAGACAGACCTCCGGAGAAAGT


* Fusion transcript sequences (Full-length transcript).
>In-frame_FOXP1_ENST00000318789_chr3_71090479_-_SH3RF2_ENST00000359120_chr5_145379621_+_3822nt
GGGGGGTGGGCGCCAGCGCCCCGGCGAACGGCAAAGAGGGAGCCGCTCCCGCTCGGGGGGCCGCTGGAGTGCCCAGCGGGAACCCGAAAG
TTTGTAAGAGGAAGAGAGCGCGCGGCGAGCGAGCGAGCGGGCCGGGGGCAGCGGCAGCGGCGCCGGGGACCATGGTGCTGCCGGCGCCTC
CTCCGCGGGCGTGAAGGCGGCGCTCCTACTCCCTCCCCGGACTCCGCGGTGTCCCAGAAGCTTTTGTTGACAATTCCAGTTTCCGAACAA
AACATTTCGGCAATGGTGAGGGCTTCGATCCCTTCTCTGATTTGCTGTCAGCCATGAACGGATGGATGTGATGCCTGCTAGCCAAAAGGC
TTCCCTCTGTGTGTTGCAGTCCTGTGGCATTATGCATGCCCCCTCCCAGTGACCCCAGGCTTTTTATGGCTGTGAGACACGTTAAAATTT
CAGGGGTAAGACGTGACCTTTTGAGGTGACTATAACTGAAGATTGCTTTACAGAAGCCAAAAAAGGTTTTTGAGTCATGATGCAAGAATC
TGGGACTGAGACAAAAAGTAACGGTTCAGCCATCCAGAATGGGTCGGGCGGCAGCAACCACTTACTAGAGTGCGGCGGTCTTCGGGAGGG
GCGGTCCAACGGAGAGACGCCGGCCGTGGACATCGGGGCAGCTGACCTCGCCCACGCCCAGCAGCAGCAGCAACAGGCACTTCAGGTGGC
AAGACAGCTCCTTCTTCAGCAGCAACAGCAGCAGCAAGTTAGTGGATTAAAATCTCCCAAGAGGAATGACAAACAACCAGCTCTTCAGGT
TCCCGTGTCAGTGGCTATGATGACACCTCAAGTTATCACTCCCCAGCAAATGCAGCAGATCCTCCAGCAACAAGTGCTGAGCCCTCAGCA
GCTCCAGGTTCTCCTCCAGCAGCAGCAGGCCCTCATGCTTCAACAGCAGCAGCTTCAAGAGTTTTATAAAAAACAACAGGAACAGTTGCA
GCTTCAACTTTTACAACAACAACATGCTGGAAAACAGCCTAAAGAGCAACAGCAGGTGGCTACCCAGCAGTTGGCTTTTCAGCAGCAGCT
TTTACAGATGCAGCAGTTACAGCAGCAGCACCTCCTGTCTTTGCAGCGCCAAGGCCTTCTGACAATTCAGCCCGGGCAGCCTGCCCTTCC
CCTTCAACCTCTTGCTCAAGGCATGATTCCAACAGAACTGCAGCAGCTCTGGAAAGAAGTGACAAGTGCTCATACTGCAGAAGAAACCAC
AGGCAACAATCACAGCAGTTTGGATCTGACCACGACATGTGTCTCCTCCTCTGCACCTTCCAAGACCTCCTTAATAATGAACCCACATGC
CTCTACCAATGGACAGCTCTCAGTCCACACTCCCAAAAGGGAAAGGTGCCTCGAGCAAAGGCCTTATGCAACTACAGAGGGCAGAATCCC
GGTGACCTAAGGTTTAATAAGGGAGATATCATCCTTCTCCGGAGACAGCTTGATGAGAATTGGTACCAGGGGGAAATCAATGGCATCAGC
GGGAACTTCCCAGCCAGCTCCGTGGAAGTCATCAAGCAGCTGCCCCAGCCGCCCCCGCTCTGCAGGGCCCTCTACAACTTCGACCTACGA
GGCAAGGACAAGAGTGAGAACCAGGATTGCCTGACCTTCCTCAAGGACGATATCATCACTGTGATCAGCCGAGTGGATGAGAACTGGGCA
GAAGGCAAGTTAGGAGATAAAGTAGGCATCTTCCCTATCTTGTTTGTAGAGCCAAACCTCACCGCAAGACACCTTTTAGAGAAGAACAAA
GGTCGCCAGTCATCCCGCACAAAAAACCTGTCCCTGGTGTCCTCGTCCTCCAGAGGCAACACGTCTACCCTCCGTAGGGGCCCAGGGTCC
AGGAGGAAGGTGCCTGGGCAGTTTTCCATCACAACAGCCTTGAACACTCTCAACCGGATGGTCCATTCTCCTTCAGGGCGCCATATGGTA
GAGATCAGCACCCCAGTGCTCATCAGCTCCAGCAACCCCTCTGTGATCACCCAGCCCATGGAGAAAGCAGACGTTCCTTCCAGCTGTGTG
GGACAGGTCAGCACTTATCACCCCGCACCTGTCTCTCCAGGACATTCCACAGCCGTGGTCAGTCTGCCTGGCTCCCAGCAACACCTCTCA
GCGAACATGTTTGTAGCCCTGCACTCCTACTCAGCCCATGGACCCGATGAGCTGGACCTGCAAAAGGGAGAAGGCGTCAGGGTCCTGGGG
AAGTGCCAGGACGGCTGGCTCAGGGGCGTCTCCTTGGTCACCGGGCGAGTCGGCATCTTCCCAAACAATTACGTCATCCCCATTTTCAGA
AAGACCTCTAGTTTTCCAGACTCCCGGAGCCCTGGTCTCTACACCACATGGACGTTATCCACCTCCTCTGTGTCCTCCCAAGGCAGCATT
TCAGAAGGTGATCCACGGCAAAGCCGTCCCTTCAAATCCGTCTTTGTGCCCACTGCCATAGTCAACCCCGTGAGAAGCACAGCCGGCCCT
GGGACTTTAGGACAAGGGTCTCTTCGGAAAGGGCGGAGCAGCATGAGAAAGAATGGATCCCTGCAGAGACCCCTCCAGTCCGGGATCCCC
ACTCTCGTGGTAGGCTCCCTCAGACGCAGCCCCACCATGGTCCTTCGGCCTCAGCAGTTCCAATTCTACCAGCCACAGGGGATCCCCTCC
TCCCCCTCAGCCGTGGTGGTGGAGATGGGGTCCAAGCCTGCCCTCACGGGGGAGCCCGCCCTCACGTGCATCAGCAGGGGCAGTGAGGCC
TGGATCCACTCCGCGGCCAGCTCCCTCATTATGGAAGACAAAGAAATCCCCATCAAGAGTGAGCCTCTGCCAAAACCGCCCGCATCTGCC
CCACCATCCATCCTGGTGAAACCAGAAAACTCAAGAAATGGCATCGAAAAGCAAGTCAAAACCGTGAGATTTCAGAATTACAGCCCTCCT
CCCACCAAACATTACACCTCCCATCCCACCTCCGGAAAGCCTGAACAGCCAGCCACCCTCAAGGCGTCCCAGCCTGAAGCAGCGTCCTTG
GGCCCAGAGATGACCGTCCTATTTGCCCACCGAAGTGGCTGCCACTCCGGACAGCAGACAGACCTCCGGAGAAAGTCAGCTCTTGGCAAG
GCCACAACCCTGGTGTCCACTGCCTCAGGCACGCAGACCGTGTTTCCCAGCAAATGAACCTACGGGTGGCTTTTCCTAGACCCCAAAGAG
GTGAATTGCATTTAAATACAGTCTGCCTCCACTGAGGGCATCCTGCCATTCTTTGGGGACTTGAGCATGGGTCCTTGTTCTTCCTATTTC
ACCTCCAGGAAAGCAAAAGTGGGAGCAGAAATTCCTGCCCTGGGTGGGAGGATAGATGGCGTGGCCTTCCAAACATACAAACATAATGAT
TTGATGCCACAAAGCTCGCTTACTCAGACCAAGGAGTGAAAAATTGTCGTGCCCACTTTATGCCCCAGCATGGAGTATGTGGCCTCTTGT
CATCCCCGTGTTACTGTGTAGAATTTCTATGGTGTCCTAAAGGGGGCTGCAGCAGGGGTGTGACAACGGTGGGATTGTTGGCGTTGCTTC
TTTGACCTTACAATATCCTCAACAAGCATTAGAACAACTTCTGCCATCTTCTGGGGCCTGTACACTGGCCACTAGTAGCTGCCATATCTT
TTTCCCTCTGTAAAGTCATAATCCTGGCTGCAAAGGGAGGATTTCTGCGCGGGGTGTGAGGTGGATACTTTGAACATTCTGAGAACCCAA

>In-frame_FOXP1_ENST00000318789_chr3_71090479_-_SH3RF2_ENST00000511217_chr5_145379621_+_6572nt
GGGGGGTGGGCGCCAGCGCCCCGGCGAACGGCAAAGAGGGAGCCGCTCCCGCTCGGGGGGCCGCTGGAGTGCCCAGCGGGAACCCGAAAG
TTTGTAAGAGGAAGAGAGCGCGCGGCGAGCGAGCGAGCGGGCCGGGGGCAGCGGCAGCGGCGCCGGGGACCATGGTGCTGCCGGCGCCTC
CTCCGCGGGCGTGAAGGCGGCGCTCCTACTCCCTCCCCGGACTCCGCGGTGTCCCAGAAGCTTTTGTTGACAATTCCAGTTTCCGAACAA
AACATTTCGGCAATGGTGAGGGCTTCGATCCCTTCTCTGATTTGCTGTCAGCCATGAACGGATGGATGTGATGCCTGCTAGCCAAAAGGC
TTCCCTCTGTGTGTTGCAGTCCTGTGGCATTATGCATGCCCCCTCCCAGTGACCCCAGGCTTTTTATGGCTGTGAGACACGTTAAAATTT
CAGGGGTAAGACGTGACCTTTTGAGGTGACTATAACTGAAGATTGCTTTACAGAAGCCAAAAAAGGTTTTTGAGTCATGATGCAAGAATC
TGGGACTGAGACAAAAAGTAACGGTTCAGCCATCCAGAATGGGTCGGGCGGCAGCAACCACTTACTAGAGTGCGGCGGTCTTCGGGAGGG
GCGGTCCAACGGAGAGACGCCGGCCGTGGACATCGGGGCAGCTGACCTCGCCCACGCCCAGCAGCAGCAGCAACAGGCACTTCAGGTGGC
AAGACAGCTCCTTCTTCAGCAGCAACAGCAGCAGCAAGTTAGTGGATTAAAATCTCCCAAGAGGAATGACAAACAACCAGCTCTTCAGGT
TCCCGTGTCAGTGGCTATGATGACACCTCAAGTTATCACTCCCCAGCAAATGCAGCAGATCCTCCAGCAACAAGTGCTGAGCCCTCAGCA
GCTCCAGGTTCTCCTCCAGCAGCAGCAGGCCCTCATGCTTCAACAGCAGCAGCTTCAAGAGTTTTATAAAAAACAACAGGAACAGTTGCA
GCTTCAACTTTTACAACAACAACATGCTGGAAAACAGCCTAAAGAGCAACAGCAGGTGGCTACCCAGCAGTTGGCTTTTCAGCAGCAGCT
TTTACAGATGCAGCAGTTACAGCAGCAGCACCTCCTGTCTTTGCAGCGCCAAGGCCTTCTGACAATTCAGCCCGGGCAGCCTGCCCTTCC
CCTTCAACCTCTTGCTCAAGGCATGATTCCAACAGAACTGCAGCAGCTCTGGAAAGAAGTGACAAGTGCTCATACTGCAGAAGAAACCAC
AGGCAACAATCACAGCAGTTTGGATCTGACCACGACATGTGTCTCCTCCTCTGCACCTTCCAAGACCTCCTTAATAATGAACCCACATGC
CTCTACCAATGGACAGCTCTCAGTCCACACTCCCAAAAGGGAAAGGTGCCTCGAGCAAAGGCCTTATGCAACTACAGAGGGCAGAATCCC
GGTGACCTAAGGTTTAATAAGGGAGATATCATCCTTCTCCGGAGACAGCTTGATGAGAATTGGTACCAGGGGGAAATCAATGGCATCAGC
GGGAACTTCCCAGCCAGCTCCGTGGAAGTCATCAAGCAGCTGCCCCAGCCGCCCCCGCTCTGCAGGGCCCTCTACAACTTCGACCTACGA
GGCAAGGACAAGAGTGAGAACCAGGATTGCCTGACCTTCCTCAAGGACGATATCATCACTGTGATCAGCCGAGTGGATGAGAACTGGGCA
GAAGGCAAGTTAGGAGATAAAGTAGGCATCTTCCCTATCTTGTTTGTAGAGCCAAACCTCACCGCAAGACACCTTTTAGAGAAGAACAAA
GGTCGCCAGTCATCCCGCACAAAAAACCTGTCCCTGGTGTCCTCGTCCTCCAGAGGCAACACGTCTACCCTCCGTAGGGGCCCAGGGTCC
AGGAGGAAGGTGCCTGGGCAGTTTTCCATCACAACAGCCTTGAACACTCTCAACCGGATGGTCCATTCTCCTTCAGGGCGCCATATGGTA
GAGATCAGCACCCCAGTGCTCATCAGCTCCAGCAACCCCTCTGTGATCACCCAGCCCATGGAGAAAGCAGACGTTCCTTCCAGCTGTGTG
GGACAGGTCAGCACTTATCACCCCGCACCTGTCTCTCCAGGACATTCCACAGCCGTGGTCAGTCTGCCTGGCTCCCAGCAACACCTCTCA
GCGAACATGTTTGTAGCCCTGCACTCCTACTCAGCCCATGGACCCGATGAGCTGGACCTGCAAAAGGGAGAAGGCGTCAGGGTCCTGGGG
AAGTGCCAGGACGGCTGGCTCAGGGGCGTCTCCTTGGTCACCGGGCGAGTCGGCATCTTCCCAAACAATTACGTCATCCCCATTTTCAGA
AAGACCTCTAGTTTTCCAGACTCCCGGAGCCCTGGTCTCTACACCACATGGACGTTATCCACCTCCTCTGTGTCCTCCCAAGGCAGCATT
TCAGAAGGTGATCCACGGCAAAGCCGTCCCTTCAAATCCGTCTTTGTGCCCACTGCCATAGTCAACCCCGTGAGAAGCACAGCCGGCCCT
GGGACTTTAGGACAAGGGTCTCTTCGGAAAGGGCGGAGCAGCATGAGAAAGAATGGATCCCTGCAGAGACCCCTCCAGTCCGGGATCCCC
ACTCTCGTGGTAGGCTCCCTCAGACGCAGCCCCACCATGGTCCTTCGGCCTCAGCAGTTCCAATTCTACCAGCCACAGGGGATCCCCTCC
TCCCCCTCAGCCGTGGTGGTGGAGATGGGGTCCAAGCCTGCCCTCACGGGGGAGCCCGCCCTCACGTGCATCAGCAGGGGCAGTGAGGCC
TGGATCCACTCCGCGGCCAGCTCCCTCATTATGGAAGACAAAGAAATCCCCATCAAGAGTGAGCCTCTGCCAAAACCGCCCGCATCTGCC
CCACCATCCATCCTGGTGAAACCAGAAAACTCAAGAAATGGCATCGAAAAGCAAGTCAAAACCGTGAGATTTCAGAATTACAGCCCTCCT
CCCACCAAACATTACACCTCCCATCCCACCTCCGGAAAGCCTGAACAGCCAGCCACCCTCAAGGCGTCCCAGCCTGAAGCAGCGTCCTTG
GGCCCAGAGATGACCGTCCTATTTGCCCACCGAAGTGGCTGCCACTCCGGACAGCAGACAGACCTCCGGAGAAAGTCAGCTCTTGGCAAG
GCCACAACCCTGGTGTCCACTGCCTCAGGCACGCAGACCGTGTTTCCCAGCAAATGAACCTACGGGTGGCTTTTCCTAGACCCCAAAGAG
AGCCTGCCTTGGTCATCTTCCCAGGAGGAATTCATGACAACTGGGATGCAGAAGAGAGCAAATGATCTGCTGGGATGGAAACTGCTCAAT
GGAGAGTTTGTGGACTGCATGATATTCCTTGAACATCAGGGATGGTACAGGGATACCAATAGTCTGGCCTCCAAGACAGGAGAGTAATAG
GAGGAAGAGCAAATCTGTCTTCACCTGCAGTATTAATGGGTGGTGGGCCAGAATGGAGGAAAGCAAGTGAGTCATGTGCTGCTACAGGTT
ACACCAAACTCCCATCCCTCTGTTACTCACTGCTGTTGTCAAAGCCAAACTTTATCTTGCTAATTTCTCACAGCTTGGCACCTAACAAAT
GACAAGGCAGGACATCCAATGCCTTCGAGCTCTGTGGTCTGGCCTGTCTCTCCAGATCAGATTTAGAGTGAGGTAGCAGATGACATAATA
TTCTCTTTGGTGTTCAATCCGAAGAGGCCAATGCTTCAGCACAATGTCCCCTAGCCATCACCCCCAGCCCGACTCCCCACCAAGCATCCT
GCATCCCTCTGCCACATCTTCATTCTTTTCCATTCTGTCTTTTCCCCGATACCTTCTGACCCCAGGGATTTCTAATAGAGCATAATGATC
AAGAAAATAAAGACCTGGTACATAAAGAGTCTCAGAAAAAAAATCCATGATGTTATATGAAAGATACCAAACTGCAATGCTTACAAAGAG
GCTATTTCAAGTAGAAAGATATAAATATCACTTATAACCATGCATCCTTTATGTTCATAAATAAGTCATCATAAAGAACAAGCCATTAGA
AGACATTCTAATCCTTGTTTTTAAAAAAAAGACTATAATCTAAGATACAATTCTAAAATTACTGTGCTAACCTGCAAGAGACATTGCTCA
CATAAATGAAATTCATATATACCGTGATGTTATTTGAACCATATATTTTCATCTTCTCCTCCTCTCTTAAGACATCAATAAGAATTTGAT
TTTTAAAGGCACATGCTGCTCTGATTATCAAAGACAATAACACAAATGCAGCATCACTGGGATATGTCGGTTGTTTTAAAGTTCAGATCC
TAATTTTACTGAGGAAGCATCCTCAGTTTTTCATCCAGCCCTGCTTGTAAACAGGATCCAGCATCAGCCAGACCATGAGCAGAGTAAGGA
TTGCATCTGGAGGTTACAGAAATGTTTTCTTCTATGTGAAGCTATCACATGCAGGGGTTAAACAGGCAGCCATCTTTTAATGCGATGAAT
AATTTGGACTTCTTAGCCACACCCTTGTCTCGGTTAACCACAGGAGGAGGTGACAATACACCACAAGAAGCCCCAGAGTTCTGGCTTTAT
CTGCCAAGTGGTAGGTGAGAAGGGAAGAGGTGGGATTGAGCACACTGGCTATTTATACCTTGTCTTCAAAGCCCTCTTAGTCACATTTCC
ATCTTCATGCATTGGCTTCTGCCTTACAATTGAGCAATAGGAAACCACCACTCCTAATTTTTGCACGTGCTGCTTTTTAAGTCTCTGGGA
ACTTTCCATGAGGTATAGTGGAGGGTTTCATAAGGATTTAGCTCTTCCTTCGAACCTGCTTGGCCGATAAACCAGATATTTTTTTAAAAC
ACAGCATACAGATTCCAAATGATCAAGGATCAAAAAGTGTTGGGGATGTCAGGAAGGATGCAAGGATGGGCTTGAATGATCACAATGAGT
CAACCCAGAAATGTGCAGTAGAATAGTTTGCTAATGGTGACATCTGAGTTGCATCTCCCGGAAATATTGTTTCTTATTATTACACTTTGG
GTCGGGGGAAGGGGTGTTAAGGGTAAAAAGAGGAAGGAGCAAATAGATAAAGAGAAAAATTCATGCCTCCAGGAAACATAAGCAGAAAAA
CTATAGACTTGTGTCTCTGCTTATTTTTTTAAGTACAGTGTTTTTAATAGACCAAAGAGAATCTCTATGAGTTAATATGTATGTGAATAA
TGTTTATAAAAGGGGTATAATGTGTTAGTCATTATGGAATATTGTATAAATAAACCTTCCATATATAAAACATATAAAAAATGATTGCTT
AGGGCAGTGGACACTTAAGGACTTCCAAACCTTTCATATCTTCATCCCAAAAAATAGAGCGTTCCAGGGCTGGCAACTTATTTCCTTAGT
ATATTCCACTGTAAAGCCAAGAGGTGTGGGGGCTTGTTTTCTGGTTTTGTAATTTGTAATAATCCGTATGGATTACTGTAAAATGTCTGT
TGCATGTGTGTTGGTGTTGGTGTTGGTGTTGTTTACCCACATGGAGTCATCAGAGATTTGTTCCACACTTTGTATCCTGGAAAACCAAAA
GGAATTTTCTTTTCTTCGAGACAGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGCCATCTTGGCTCACTGCAACCTCCGCCTC
CCGAATTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGCGTGCCACCTTGCCCTGCTAATTTTTTGTATTTTT
AGTAGAGACGGGGTCTCACCGTGTTAGCCAGGATTGTCTCGATCTCCTGACCTTGTGATCTGCCCGCCTCGGCCTCCCAAAGTGCTGGGA
TTACAGACGTGAGCCACCATGCCCGGCCTGGAATTTTCTAGTAAGAAGAAAAACATACAGAATATGTCTTCACTGTTGGGTAACTCTCAA
ATTTGTAGCAATCCAGATTTTTTGTAAAACTGTGCTAATGGGATATTTAATGTCAGAGTTATTGTCTCTCACTTCAATATCTAGTACTGG
ATAATGTTTCTCCTGGGAGCACGTATTTTTTTTTCAAGTCCTCTTTTCCTGGACTTAACATGTTCTTCTAGAAGACACCAGAAGTCATGA
CCCTAAGCCCCCTCCCTTCAGGACCACTTTCTACCATCGGTTTTCAAAAAACTATCCACATGTTAATTCTGTTTTATGTTCTGTGATTCT
GTGGTAGACTCAGTGCTTTCAGAGTCCAGAGCTTGACTTGGGTTAGTGGCCTTAATGAAGTGCTAAATTTGCTCTTTACCGCGAGACTGA
TCAGAAGAAGCAAAAGGGGAAAGGGGGCTAGAGGTCCACTCGCACCTTTTACATCAGACAAGAGGAGGACTGTGCCAGAAATCTGTGCAT
GAAACACCATCTGCTCTTCATGCAGGGAGGGGTCAACCGTGTGAACGTGCAGAGATTACTCGAGCCTTCTTTGCCAAAAATATGCATTCT
TCCCAGCTGTAAGCGTGTGAAGCCAAATATGTCTTTTAGCATGAAACAATAAAAACATGTTTATTTTCACTTAATAGGTTATTCCCCAGG

>In-frame_FOXP1_ENST00000493089_chr3_71090479_-_SH3RF2_ENST00000359120_chr5_145379621_+_3925nt
ATTTATTGTGTGGCGGTTGCACGCTGTACTCGCGGCGGCCCGGCCCTCGCCCGGGAGTGCGTGTGTGCGCGCGTGTGTGCGCGAGTGAGT
GTGTGCGCGGGGTGCGCGCGCGGGCGGGAGTGGGCGCGCGCGGGGAAAGGCCCGAAAACACCTTAGTTTGCACCGAGAGACCATTTGCAG
CGGAACCCGAAAGTTTGTAAGAGGAAGAGAGCGCGCGGCGAGCGAGCGAGCGGGCCGGGGGCAGCGGCAGCGGCGCCGGGGACCATGGTG
CTGCCGGCGCCTCCTCCGCGGGCGTGAAGGCGGCGCTCCTACTCCCTCCCCGGACTCCGCGGTGTCCCAGAAGCTTTTGTTGACAATTCC
AGTTTCCGAACAAAACATTTCGGCAATGGTGAGGGCTTCGATCCCTTCTCTGATTTGCTGTCAGCCATGAACGGATGGATGTGATGCCTG
CTAGCCAAAAGGCTTCCCTCTGTGTGTTGCAGTCCTGTGGCATTATGCATGCCCCCTCCCAGTGACCCCAGGCTTTTTATGGCTGTGAGA
CACGTTAAAATTTCAGGGGTAAGACGTGACCTTTTGAGGTGACTATAACTGAAGATTGCTTTACAGAAGCCAAAAAAGGTTTTTGAGTCA
TGATGCAAGAATCTGGGACTGAGACAAAAAGTAACGGTTCAGCCATCCAGAATGGGTCGGGCGGCAGCAACCACTTACTAGAGTGCGGCG
GTCTTCGGGAGGGGCGGTCCAACGGAGAGACGCCGGCCGTGGACATCGGGGCAGCTGACCTCGCCCACGCCCAGCAGCAGCAGCAACAGG
CACTTCAGGTGGCAAGACAGCTCCTTCTTCAGCAGCAACAGCAGCAGCAAGTTAGTGGATTAAAATCTCCCAAGAGGAATGACAAACAAC
CAGCTCTTCAGGTTCCCGTGTCAGTGGCTATGATGACACCTCAAGTTATCACTCCCCAGCAAATGCAGCAGATCCTCCAGCAACAAGTGC
TGAGCCCTCAGCAGCTCCAGGTTCTCCTCCAGCAGCAGCAGGCCCTCATGCTTCAACAGCAGCAGCTTCAAGAGTTTTATAAAAAACAAC
AGGAACAGTTGCAGCTTCAACTTTTACAACAACAACATGCTGGAAAACAGCCTAAAGAGCAACAGCAGGTGGCTACCCAGCAGTTGGCTT
TTCAGCAGCAGCTTTTACAGATGCAGCAGTTACAGCAGCAGCACCTCCTGTCTTTGCAGCGCCAAGGCCTTCTGACAATTCAGCCCGGGC
AGCCTGCCCTTCCCCTTCAACCTCTTGCTCAAGGCATGATTCCAACAGAACTGCAGCAGCTCTGGAAAGAAGTGACAAGTGCTCATACTG
CAGAAGAAACCACAGGCAACAATCACAGCAGTTTGGATCTGACCACGACATGTGTCTCCTCCTCTGCACCTTCCAAGACCTCCTTAATAA
TGAACCCACATGCCTCTACCAATGGACAGCTCTCAGTCCACACTCCCAAAAGGGAAAGGTGCCTCGAGCAAAGGCCTTATGCAACTACAG
AGGGCAGAATCCCGGTGACCTAAGGTTTAATAAGGGAGATATCATCCTTCTCCGGAGACAGCTTGATGAGAATTGGTACCAGGGGGAAAT
CAATGGCATCAGCGGGAACTTCCCAGCCAGCTCCGTGGAAGTCATCAAGCAGCTGCCCCAGCCGCCCCCGCTCTGCAGGGCCCTCTACAA
CTTCGACCTACGAGGCAAGGACAAGAGTGAGAACCAGGATTGCCTGACCTTCCTCAAGGACGATATCATCACTGTGATCAGCCGAGTGGA
TGAGAACTGGGCAGAAGGCAAGTTAGGAGATAAAGTAGGCATCTTCCCTATCTTGTTTGTAGAGCCAAACCTCACCGCAAGACACCTTTT
AGAGAAGAACAAAGGTCGCCAGTCATCCCGCACAAAAAACCTGTCCCTGGTGTCCTCGTCCTCCAGAGGCAACACGTCTACCCTCCGTAG
GGGCCCAGGGTCCAGGAGGAAGGTGCCTGGGCAGTTTTCCATCACAACAGCCTTGAACACTCTCAACCGGATGGTCCATTCTCCTTCAGG
GCGCCATATGGTAGAGATCAGCACCCCAGTGCTCATCAGCTCCAGCAACCCCTCTGTGATCACCCAGCCCATGGAGAAAGCAGACGTTCC
TTCCAGCTGTGTGGGACAGGTCAGCACTTATCACCCCGCACCTGTCTCTCCAGGACATTCCACAGCCGTGGTCAGTCTGCCTGGCTCCCA
GCAACACCTCTCAGCGAACATGTTTGTAGCCCTGCACTCCTACTCAGCCCATGGACCCGATGAGCTGGACCTGCAAAAGGGAGAAGGCGT
CAGGGTCCTGGGGAAGTGCCAGGACGGCTGGCTCAGGGGCGTCTCCTTGGTCACCGGGCGAGTCGGCATCTTCCCAAACAATTACGTCAT
CCCCATTTTCAGAAAGACCTCTAGTTTTCCAGACTCCCGGAGCCCTGGTCTCTACACCACATGGACGTTATCCACCTCCTCTGTGTCCTC
CCAAGGCAGCATTTCAGAAGGTGATCCACGGCAAAGCCGTCCCTTCAAATCCGTCTTTGTGCCCACTGCCATAGTCAACCCCGTGAGAAG
CACAGCCGGCCCTGGGACTTTAGGACAAGGGTCTCTTCGGAAAGGGCGGAGCAGCATGAGAAAGAATGGATCCCTGCAGAGACCCCTCCA
GTCCGGGATCCCCACTCTCGTGGTAGGCTCCCTCAGACGCAGCCCCACCATGGTCCTTCGGCCTCAGCAGTTCCAATTCTACCAGCCACA
GGGGATCCCCTCCTCCCCCTCAGCCGTGGTGGTGGAGATGGGGTCCAAGCCTGCCCTCACGGGGGAGCCCGCCCTCACGTGCATCAGCAG
GGGCAGTGAGGCCTGGATCCACTCCGCGGCCAGCTCCCTCATTATGGAAGACAAAGAAATCCCCATCAAGAGTGAGCCTCTGCCAAAACC
GCCCGCATCTGCCCCACCATCCATCCTGGTGAAACCAGAAAACTCAAGAAATGGCATCGAAAAGCAAGTCAAAACCGTGAGATTTCAGAA
TTACAGCCCTCCTCCCACCAAACATTACACCTCCCATCCCACCTCCGGAAAGCCTGAACAGCCAGCCACCCTCAAGGCGTCCCAGCCTGA
AGCAGCGTCCTTGGGCCCAGAGATGACCGTCCTATTTGCCCACCGAAGTGGCTGCCACTCCGGACAGCAGACAGACCTCCGGAGAAAGTC
AGCTCTTGGCAAGGCCACAACCCTGGTGTCCACTGCCTCAGGCACGCAGACCGTGTTTCCCAGCAAATGAACCTACGGGTGGCTTTTCCT
AGACCCCAAAGAGGTGAATTGCATTTAAATACAGTCTGCCTCCACTGAGGGCATCCTGCCATTCTTTGGGGACTTGAGCATGGGTCCTTG
TTCTTCCTATTTCACCTCCAGGAAAGCAAAAGTGGGAGCAGAAATTCCTGCCCTGGGTGGGAGGATAGATGGCGTGGCCTTCCAAACATA
CAAACATAATGATTTGATGCCACAAAGCTCGCTTACTCAGACCAAGGAGTGAAAAATTGTCGTGCCCACTTTATGCCCCAGCATGGAGTA
TGTGGCCTCTTGTCATCCCCGTGTTACTGTGTAGAATTTCTATGGTGTCCTAAAGGGGGCTGCAGCAGGGGTGTGACAACGGTGGGATTG
TTGGCGTTGCTTCTTTGACCTTACAATATCCTCAACAAGCATTAGAACAACTTCTGCCATCTTCTGGGGCCTGTACACTGGCCACTAGTA
GCTGCCATATCTTTTTCCCTCTGTAAAGTCATAATCCTGGCTGCAAAGGGAGGATTTCTGCGCGGGGTGTGAGGTGGATACTTTGAACAT

>In-frame_FOXP1_ENST00000493089_chr3_71090479_-_SH3RF2_ENST00000511217_chr5_145379621_+_6675nt
ATTTATTGTGTGGCGGTTGCACGCTGTACTCGCGGCGGCCCGGCCCTCGCCCGGGAGTGCGTGTGTGCGCGCGTGTGTGCGCGAGTGAGT
GTGTGCGCGGGGTGCGCGCGCGGGCGGGAGTGGGCGCGCGCGGGGAAAGGCCCGAAAACACCTTAGTTTGCACCGAGAGACCATTTGCAG
CGGAACCCGAAAGTTTGTAAGAGGAAGAGAGCGCGCGGCGAGCGAGCGAGCGGGCCGGGGGCAGCGGCAGCGGCGCCGGGGACCATGGTG
CTGCCGGCGCCTCCTCCGCGGGCGTGAAGGCGGCGCTCCTACTCCCTCCCCGGACTCCGCGGTGTCCCAGAAGCTTTTGTTGACAATTCC
AGTTTCCGAACAAAACATTTCGGCAATGGTGAGGGCTTCGATCCCTTCTCTGATTTGCTGTCAGCCATGAACGGATGGATGTGATGCCTG
CTAGCCAAAAGGCTTCCCTCTGTGTGTTGCAGTCCTGTGGCATTATGCATGCCCCCTCCCAGTGACCCCAGGCTTTTTATGGCTGTGAGA
CACGTTAAAATTTCAGGGGTAAGACGTGACCTTTTGAGGTGACTATAACTGAAGATTGCTTTACAGAAGCCAAAAAAGGTTTTTGAGTCA
TGATGCAAGAATCTGGGACTGAGACAAAAAGTAACGGTTCAGCCATCCAGAATGGGTCGGGCGGCAGCAACCACTTACTAGAGTGCGGCG
GTCTTCGGGAGGGGCGGTCCAACGGAGAGACGCCGGCCGTGGACATCGGGGCAGCTGACCTCGCCCACGCCCAGCAGCAGCAGCAACAGG
CACTTCAGGTGGCAAGACAGCTCCTTCTTCAGCAGCAACAGCAGCAGCAAGTTAGTGGATTAAAATCTCCCAAGAGGAATGACAAACAAC
CAGCTCTTCAGGTTCCCGTGTCAGTGGCTATGATGACACCTCAAGTTATCACTCCCCAGCAAATGCAGCAGATCCTCCAGCAACAAGTGC
TGAGCCCTCAGCAGCTCCAGGTTCTCCTCCAGCAGCAGCAGGCCCTCATGCTTCAACAGCAGCAGCTTCAAGAGTTTTATAAAAAACAAC
AGGAACAGTTGCAGCTTCAACTTTTACAACAACAACATGCTGGAAAACAGCCTAAAGAGCAACAGCAGGTGGCTACCCAGCAGTTGGCTT
TTCAGCAGCAGCTTTTACAGATGCAGCAGTTACAGCAGCAGCACCTCCTGTCTTTGCAGCGCCAAGGCCTTCTGACAATTCAGCCCGGGC
AGCCTGCCCTTCCCCTTCAACCTCTTGCTCAAGGCATGATTCCAACAGAACTGCAGCAGCTCTGGAAAGAAGTGACAAGTGCTCATACTG
CAGAAGAAACCACAGGCAACAATCACAGCAGTTTGGATCTGACCACGACATGTGTCTCCTCCTCTGCACCTTCCAAGACCTCCTTAATAA
TGAACCCACATGCCTCTACCAATGGACAGCTCTCAGTCCACACTCCCAAAAGGGAAAGGTGCCTCGAGCAAAGGCCTTATGCAACTACAG
AGGGCAGAATCCCGGTGACCTAAGGTTTAATAAGGGAGATATCATCCTTCTCCGGAGACAGCTTGATGAGAATTGGTACCAGGGGGAAAT
CAATGGCATCAGCGGGAACTTCCCAGCCAGCTCCGTGGAAGTCATCAAGCAGCTGCCCCAGCCGCCCCCGCTCTGCAGGGCCCTCTACAA
CTTCGACCTACGAGGCAAGGACAAGAGTGAGAACCAGGATTGCCTGACCTTCCTCAAGGACGATATCATCACTGTGATCAGCCGAGTGGA
TGAGAACTGGGCAGAAGGCAAGTTAGGAGATAAAGTAGGCATCTTCCCTATCTTGTTTGTAGAGCCAAACCTCACCGCAAGACACCTTTT
AGAGAAGAACAAAGGTCGCCAGTCATCCCGCACAAAAAACCTGTCCCTGGTGTCCTCGTCCTCCAGAGGCAACACGTCTACCCTCCGTAG
GGGCCCAGGGTCCAGGAGGAAGGTGCCTGGGCAGTTTTCCATCACAACAGCCTTGAACACTCTCAACCGGATGGTCCATTCTCCTTCAGG
GCGCCATATGGTAGAGATCAGCACCCCAGTGCTCATCAGCTCCAGCAACCCCTCTGTGATCACCCAGCCCATGGAGAAAGCAGACGTTCC
TTCCAGCTGTGTGGGACAGGTCAGCACTTATCACCCCGCACCTGTCTCTCCAGGACATTCCACAGCCGTGGTCAGTCTGCCTGGCTCCCA
GCAACACCTCTCAGCGAACATGTTTGTAGCCCTGCACTCCTACTCAGCCCATGGACCCGATGAGCTGGACCTGCAAAAGGGAGAAGGCGT
CAGGGTCCTGGGGAAGTGCCAGGACGGCTGGCTCAGGGGCGTCTCCTTGGTCACCGGGCGAGTCGGCATCTTCCCAAACAATTACGTCAT
CCCCATTTTCAGAAAGACCTCTAGTTTTCCAGACTCCCGGAGCCCTGGTCTCTACACCACATGGACGTTATCCACCTCCTCTGTGTCCTC
CCAAGGCAGCATTTCAGAAGGTGATCCACGGCAAAGCCGTCCCTTCAAATCCGTCTTTGTGCCCACTGCCATAGTCAACCCCGTGAGAAG
CACAGCCGGCCCTGGGACTTTAGGACAAGGGTCTCTTCGGAAAGGGCGGAGCAGCATGAGAAAGAATGGATCCCTGCAGAGACCCCTCCA
GTCCGGGATCCCCACTCTCGTGGTAGGCTCCCTCAGACGCAGCCCCACCATGGTCCTTCGGCCTCAGCAGTTCCAATTCTACCAGCCACA
GGGGATCCCCTCCTCCCCCTCAGCCGTGGTGGTGGAGATGGGGTCCAAGCCTGCCCTCACGGGGGAGCCCGCCCTCACGTGCATCAGCAG
GGGCAGTGAGGCCTGGATCCACTCCGCGGCCAGCTCCCTCATTATGGAAGACAAAGAAATCCCCATCAAGAGTGAGCCTCTGCCAAAACC
GCCCGCATCTGCCCCACCATCCATCCTGGTGAAACCAGAAAACTCAAGAAATGGCATCGAAAAGCAAGTCAAAACCGTGAGATTTCAGAA
TTACAGCCCTCCTCCCACCAAACATTACACCTCCCATCCCACCTCCGGAAAGCCTGAACAGCCAGCCACCCTCAAGGCGTCCCAGCCTGA
AGCAGCGTCCTTGGGCCCAGAGATGACCGTCCTATTTGCCCACCGAAGTGGCTGCCACTCCGGACAGCAGACAGACCTCCGGAGAAAGTC
AGCTCTTGGCAAGGCCACAACCCTGGTGTCCACTGCCTCAGGCACGCAGACCGTGTTTCCCAGCAAATGAACCTACGGGTGGCTTTTCCT
AGACCCCAAAGAGAGCCTGCCTTGGTCATCTTCCCAGGAGGAATTCATGACAACTGGGATGCAGAAGAGAGCAAATGATCTGCTGGGATG
GAAACTGCTCAATGGAGAGTTTGTGGACTGCATGATATTCCTTGAACATCAGGGATGGTACAGGGATACCAATAGTCTGGCCTCCAAGAC
AGGAGAGTAATAGGAGGAAGAGCAAATCTGTCTTCACCTGCAGTATTAATGGGTGGTGGGCCAGAATGGAGGAAAGCAAGTGAGTCATGT
GCTGCTACAGGTTACACCAAACTCCCATCCCTCTGTTACTCACTGCTGTTGTCAAAGCCAAACTTTATCTTGCTAATTTCTCACAGCTTG
GCACCTAACAAATGACAAGGCAGGACATCCAATGCCTTCGAGCTCTGTGGTCTGGCCTGTCTCTCCAGATCAGATTTAGAGTGAGGTAGC
AGATGACATAATATTCTCTTTGGTGTTCAATCCGAAGAGGCCAATGCTTCAGCACAATGTCCCCTAGCCATCACCCCCAGCCCGACTCCC
CACCAAGCATCCTGCATCCCTCTGCCACATCTTCATTCTTTTCCATTCTGTCTTTTCCCCGATACCTTCTGACCCCAGGGATTTCTAATA
GAGCATAATGATCAAGAAAATAAAGACCTGGTACATAAAGAGTCTCAGAAAAAAAATCCATGATGTTATATGAAAGATACCAAACTGCAA
TGCTTACAAAGAGGCTATTTCAAGTAGAAAGATATAAATATCACTTATAACCATGCATCCTTTATGTTCATAAATAAGTCATCATAAAGA
ACAAGCCATTAGAAGACATTCTAATCCTTGTTTTTAAAAAAAAGACTATAATCTAAGATACAATTCTAAAATTACTGTGCTAACCTGCAA
GAGACATTGCTCACATAAATGAAATTCATATATACCGTGATGTTATTTGAACCATATATTTTCATCTTCTCCTCCTCTCTTAAGACATCA
ATAAGAATTTGATTTTTAAAGGCACATGCTGCTCTGATTATCAAAGACAATAACACAAATGCAGCATCACTGGGATATGTCGGTTGTTTT
AAAGTTCAGATCCTAATTTTACTGAGGAAGCATCCTCAGTTTTTCATCCAGCCCTGCTTGTAAACAGGATCCAGCATCAGCCAGACCATG
AGCAGAGTAAGGATTGCATCTGGAGGTTACAGAAATGTTTTCTTCTATGTGAAGCTATCACATGCAGGGGTTAAACAGGCAGCCATCTTT
TAATGCGATGAATAATTTGGACTTCTTAGCCACACCCTTGTCTCGGTTAACCACAGGAGGAGGTGACAATACACCACAAGAAGCCCCAGA
GTTCTGGCTTTATCTGCCAAGTGGTAGGTGAGAAGGGAAGAGGTGGGATTGAGCACACTGGCTATTTATACCTTGTCTTCAAAGCCCTCT
TAGTCACATTTCCATCTTCATGCATTGGCTTCTGCCTTACAATTGAGCAATAGGAAACCACCACTCCTAATTTTTGCACGTGCTGCTTTT
TAAGTCTCTGGGAACTTTCCATGAGGTATAGTGGAGGGTTTCATAAGGATTTAGCTCTTCCTTCGAACCTGCTTGGCCGATAAACCAGAT
ATTTTTTTAAAACACAGCATACAGATTCCAAATGATCAAGGATCAAAAAGTGTTGGGGATGTCAGGAAGGATGCAAGGATGGGCTTGAAT
GATCACAATGAGTCAACCCAGAAATGTGCAGTAGAATAGTTTGCTAATGGTGACATCTGAGTTGCATCTCCCGGAAATATTGTTTCTTAT
TATTACACTTTGGGTCGGGGGAAGGGGTGTTAAGGGTAAAAAGAGGAAGGAGCAAATAGATAAAGAGAAAAATTCATGCCTCCAGGAAAC
ATAAGCAGAAAAACTATAGACTTGTGTCTCTGCTTATTTTTTTAAGTACAGTGTTTTTAATAGACCAAAGAGAATCTCTATGAGTTAATA
TGTATGTGAATAATGTTTATAAAAGGGGTATAATGTGTTAGTCATTATGGAATATTGTATAAATAAACCTTCCATATATAAAACATATAA
AAAATGATTGCTTAGGGCAGTGGACACTTAAGGACTTCCAAACCTTTCATATCTTCATCCCAAAAAATAGAGCGTTCCAGGGCTGGCAAC
TTATTTCCTTAGTATATTCCACTGTAAAGCCAAGAGGTGTGGGGGCTTGTTTTCTGGTTTTGTAATTTGTAATAATCCGTATGGATTACT
GTAAAATGTCTGTTGCATGTGTGTTGGTGTTGGTGTTGGTGTTGTTTACCCACATGGAGTCATCAGAGATTTGTTCCACACTTTGTATCC
TGGAAAACCAAAAGGAATTTTCTTTTCTTCGAGACAGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGCCATCTTGGCTCACTG
CAACCTCCGCCTCCCGAATTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGCGTGCCACCTTGCCCTGCTAAT
TTTTTGTATTTTTAGTAGAGACGGGGTCTCACCGTGTTAGCCAGGATTGTCTCGATCTCCTGACCTTGTGATCTGCCCGCCTCGGCCTCC
CAAAGTGCTGGGATTACAGACGTGAGCCACCATGCCCGGCCTGGAATTTTCTAGTAAGAAGAAAAACATACAGAATATGTCTTCACTGTT
GGGTAACTCTCAAATTTGTAGCAATCCAGATTTTTTGTAAAACTGTGCTAATGGGATATTTAATGTCAGAGTTATTGTCTCTCACTTCAA
TATCTAGTACTGGATAATGTTTCTCCTGGGAGCACGTATTTTTTTTTCAAGTCCTCTTTTCCTGGACTTAACATGTTCTTCTAGAAGACA
CCAGAAGTCATGACCCTAAGCCCCCTCCCTTCAGGACCACTTTCTACCATCGGTTTTCAAAAAACTATCCACATGTTAATTCTGTTTTAT
GTTCTGTGATTCTGTGGTAGACTCAGTGCTTTCAGAGTCCAGAGCTTGACTTGGGTTAGTGGCCTTAATGAAGTGCTAAATTTGCTCTTT
ACCGCGAGACTGATCAGAAGAAGCAAAAGGGGAAAGGGGGCTAGAGGTCCACTCGCACCTTTTACATCAGACAAGAGGAGGACTGTGCCA
GAAATCTGTGCATGAAACACCATCTGCTCTTCATGCAGGGAGGGGTCAACCGTGTGAACGTGCAGAGATTACTCGAGCCTTCTTTGCCAA
AAATATGCATTCTTCCCAGCTGTAAGCGTGTGAAGCCAAATATGTCTTTTAGCATGAAACAATAAAAACATGTTTATTTTCACTTAATAG


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FusionGenePPI for FOXP1_SH3RF2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
FOXP1CTBP1, FOXP1, FOXP2, FOXP4, GATAD2B, MTA1, NCOR2, ELAVL1, MYC, IL3RA, CCDC183, UNK, RCC1, HOXD13, QSER1, SATB1, SATB2, CTBP2, MYH10, LIG3, C10orf2, CUX1, VRK3, XRCC1, CHD1L, RPA2, BLM, MRE11A, MYL12B, TBP, TP53, TTF2, ZBTB10, MYL9, RPA3, TFCP2, TOP2A, UBP1, FOXP3, AURKA, SNRNP70SH3RF2UBE2N, PPP1CA, RAC1, SH3RF1, CUL4A, FASLG, APP, PPP1CC, HSP90AA1, CCDC50, DDX1, DDX6, DNTTIP1, EIF4A1, G3BP1, KARS, LSM12, NSMAF, NUFIP2, PAK4, PCMT1, RAD23A, U2AF2, GOLGA2, RBPMS, MTUS2, AMOTL2, BANP, HOMEZ, LZTS2, SPERT, CENPJ, LMNA


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000359120+110370_459126730PAK4
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000511217+010370_4591261697PAK4
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000359120+110641_646126730PPP1CA
TgeneSH3RF2chr3:71090479chr5:145379621ENST00000511217+010641_6461261697PPP1CA


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for FOXP1_SH3RF2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for FOXP1_SH3RF2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneFOXP1C0024232Lymphatic Metastasis1CTD_human
HgeneFOXP1C0027626Neoplasm Invasiveness1CTD_human
HgeneFOXP1C0030297Pancreatic Neoplasm1CTD_human
HgeneFOXP1C0042900Vitiligo1CTD_human
HgeneFOXP1C0279628Adenocarcinoma Of Esophagus1CTD_human
HgeneFOXP1C1510586Autism Spectrum Disorders1CTD_human
HgeneFOXP1C3495559Juvenile arthritis1CTD_human
HgeneFOXP1C4013764MENTAL RETARDATION WITH LANGUAGE IMPAIRMENT AND WITH OR WITHOUT AUTISTIC FEATURES1CTD_human;ORPHANET;UNIPROT