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Fusion gene ID: 13812 |
FusionGeneSummary for FOXN3_SLC25A21 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FOXN3_SLC25A21 | Fusion gene ID: 13812 | Hgene | Tgene | Gene symbol | FOXN3 | SLC25A21 | Gene ID | 1112 | 89874 |
| Gene name | forkhead box N3 | solute carrier family 25 member 21 | |
| Synonyms | C14orf116|CHES1|PRO1635 | ODC|ODC1 | |
| Cytomap | 14q31.3-q32.11 | 14q13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | forkhead box protein N3checkpoint suppressor 1 | mitochondrial 2-oxodicarboxylate carrieroxodicarboxylate carriersolute carrier family 25 (mitochondrial oxoadipate carrier), member 21solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | O00409 | Q9BQT8 | |
| Ensembl transtripts involved in fusion gene | ENST00000345097, ENST00000261302, ENST00000557258, ENST00000555353, ENST00000555658, | ENST00000555449, ENST00000331299, ENST00000557611, | |
| Fusion gene scores | * DoF score | 7 X 7 X 4=196 | 8 X 4 X 6=192 |
| # samples | 7 | 9 | |
| ** MAII score | log2(7/196*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/192*10)=-1.09310940439148 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FOXN3 [Title/Abstract] AND SLC25A21 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | FOXN3 | GO:0045892 | negative regulation of transcription, DNA-templated | 16102918 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-44-7669-01A | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000345097 | ENST00000555449 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| Frame-shift | ENST00000345097 | ENST00000331299 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| 5CDS-5UTR | ENST00000345097 | ENST00000557611 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| In-frame | ENST00000261302 | ENST00000555449 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| In-frame | ENST00000261302 | ENST00000331299 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| 5CDS-5UTR | ENST00000261302 | ENST00000557611 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| intron-3CDS | ENST00000557258 | ENST00000555449 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| intron-3CDS | ENST00000557258 | ENST00000331299 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| intron-5UTR | ENST00000557258 | ENST00000557611 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| intron-3CDS | ENST00000555353 | ENST00000555449 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| intron-3CDS | ENST00000555353 | ENST00000331299 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| intron-5UTR | ENST00000555353 | ENST00000557611 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| intron-3CDS | ENST00000555658 | ENST00000555449 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| intron-3CDS | ENST00000555658 | ENST00000331299 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
| intron-5UTR | ENST00000555658 | ENST00000557611 | FOXN3 | chr14 | 89656728 | - | SLC25A21 | chr14 | 37344209 | - |
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FusionProtFeatures for FOXN3_SLC25A21 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FOXN3 | SLC25A21 |
| Acts as a transcriptional repressor. May be involved inDNA damage-inducible cell cycle arrests (checkpoints).{ECO:0000269|PubMed:16102918}. | Transports C5-C7 oxodicarboxylates across the innermembranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent,pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, andcitrate. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for FOXN3_SLC25A21 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FOXN3_ENST00000261302_chr14_89656728_-_SLC25A21_ENST00000555449_chr14_37344209_-_546aa MGPVMPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDL DDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERS QSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIWPGSTFFKRNGALLQDPDIDAASAMMLLNTPPEIQAG CLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALTFA IAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDP ILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYS >In-frame_FOXN3_ENST00000261302_chr14_89656728_-_SLC25A21_ENST00000331299_chr14_37344209_-_547aa MGPVMPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDL DDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERS QSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIWPGSTFFKRNGALLQDPDIDAASAMMLLNTPPEIQAG CLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALTFA IAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDP ILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FOXN3_ENST00000261302_chr14_89656728_-_SLC25A21_ENST00000555449_chr14_37344209_-_1638nt ATGGGTCCAGTCATGCCTCCCAGTAAGAAGCCAGAAAGCTCAGGAATTAGTGTCTCCAGTGGACTGAGTCAGTGTTACGGGGGCAGCGGT TTCTCCAAGGCCCTTCAGGAAGACGATGACCTCGACTTTTCTCTGCCTGACATCCGATTAGAAGAGGGGGCCATGGAAGATGAAGAGCTG ACCAACCTGAACTGGCTGCACGAGAGCAAGAACTTGCTGAAGAGCTTTGGGGAGTCGGTCCTCAGGAGTGTCAGCCCCGTCCAGGACCTG GACGATGACACCCCCCCATCCCCTGCCCACTCTGACATGCCCTACGATGCCAGGCAGAACCCCAACTGCAAACCCCCCTACTCCTTCAGC TGCCTCATATTTATGGCCATCGAGGACTCTCCAACCAAGCGCCTGCCAGTGAAGGATATCTACAACTGGATCTTGGAACATTTTCCGTAT TTTGCAAATGCACCTACTGGGTGGAAAAACTCAGTGAGACACAATTTATCATTGAATAAGTGTTTTAAGAAAGTGGACAAAGAGAGGAGT CAGAGTATTGGGAAAGGGTCGTTGTGGTGCATAGACCCAGAGTATAGACAAAATCTAATTCAGGCTTTGAAAAAGACACCTTATCACCCA CACCCACACGTGTTCAATACACCTCCCACCTGTCCTCAGGCATATCAAAGCACATCAGGTCCACCCATCTGGCCGGGCAGTACCTTCTTC AAGAGAAATGGAGCCCTTCTCCAAGATCCTGACATTGATGCTGCCAGTGCCATGATGCTTTTGAATACTCCCCCTGAGATACAAGCAGGT TGTCTTGTAGAAATTTGCCTGATGCACCCCCTAGATGTGGTGAAAACCAGGTTTCAGATTCAGAGATGTGCAACCGATCCAAACAGTTAT AAAAGCTTGGTAGACAGCTTTCGAATGATTTTCCAAATGGAAGGGTTATTTGGTTTTTACAAGGGAATTCTGCCACCTATCTTGGCTGAA ACCCCAAAAAGAGCAGTGAAGTTTTTCACCTTTGAGCAGTACAAGAAATTGCTGGGATATGTGTCACTGTCACCAGCATTGACATTCGCC ATTGCTGGATTGGGATCTGGACTAACAGAAGCCATTGTAGTTAACCCTTTTGAGGTAGTAAAAGTTGGCTTGCAAGCAAATCGGAACACA TTTGCAGAGCAACCATCCACTGTGGGTTATGCAAGACAAATCATTAAGAAGGAAGGCTGGGGACTCCAGGGCCTCAACAAAGGATTAACT GCAACTTTGGGACGACATGGAGTTTTCAACATGGTTTATTTTGGCTTCTACTACAATGTCAAAAACATGATTCCTGTCAATAAGGATCCA ATCTTGGAGTTTTGGAGAAAATTTGGGATTGGTCTTCTCTCGGGGACAATAGCCTCAGTCATTAACATCCCTTTTGATGTTGCCAAAAGT AGGATTCAAGGGCCTCAACCAGTTCCTGGAGAGATCAAGTACAGAACCTGTTTTAAAACAATGGCAACAGTCTATCAGGAAGAAGGGATT TTAGCTTTGTACAAAGGCCTGCTTCCCAAGATTATGAGACTTGGACCAGGTGGTGCAGTGATGCTGCTGGTTTATGAATACACCTATTCA >In-frame_FOXN3_ENST00000261302_chr14_89656728_-_SLC25A21_ENST00000331299_chr14_37344209_-_1641nt ATGGGTCCAGTCATGCCTCCCAGTAAGAAGCCAGAAAGCTCAGGAATTAGTGTCTCCAGTGGACTGAGTCAGTGTTACGGGGGCAGCGGT TTCTCCAAGGCCCTTCAGGAAGACGATGACCTCGACTTTTCTCTGCCTGACATCCGATTAGAAGAGGGGGCCATGGAAGATGAAGAGCTG ACCAACCTGAACTGGCTGCACGAGAGCAAGAACTTGCTGAAGAGCTTTGGGGAGTCGGTCCTCAGGAGTGTCAGCCCCGTCCAGGACCTG GACGATGACACCCCCCCATCCCCTGCCCACTCTGACATGCCCTACGATGCCAGGCAGAACCCCAACTGCAAACCCCCCTACTCCTTCAGC TGCCTCATATTTATGGCCATCGAGGACTCTCCAACCAAGCGCCTGCCAGTGAAGGATATCTACAACTGGATCTTGGAACATTTTCCGTAT TTTGCAAATGCACCTACTGGGTGGAAAAACTCAGTGAGACACAATTTATCATTGAATAAGTGTTTTAAGAAAGTGGACAAAGAGAGGAGT CAGAGTATTGGGAAAGGGTCGTTGTGGTGCATAGACCCAGAGTATAGACAAAATCTAATTCAGGCTTTGAAAAAGACACCTTATCACCCA CACCCACACGTGTTCAATACACCTCCCACCTGTCCTCAGGCATATCAAAGCACATCAGGTCCACCCATCTGGCCGGGCAGTACCTTCTTC AAGAGAAATGGAGCCCTTCTCCAAGATCCTGACATTGATGCTGCCAGTGCCATGATGCTTTTGAATACTCCCCCTGAGATACAAGCAGGT TGTCTTGTAGAAATTTGCCTGATGCACCCCCTAGATGTGGTGAAAACCAGGTTTCAGATTCAGAGATGTGCAACCGATCCAAACAGTTAT AAAAGCTTGGTAGACAGCTTTCGAATGATTTTCCAAATGGAAGGGTTATTTGGTTTTTACAAGGGAATTCTGCCACCTATCTTGGCTGAA ACCCCAAAAAGAGCAGTGAAGTTTTTCACCTTTGAGCAGTACAAGAAATTGCTGGGATATGTGTCACTGTCACCAGCATTGACATTCGCC ATTGCTGGATTGGGATCTGGACTAACAGAAGCCATTGTAGTTAACCCTTTTGAGGTAGTAAAAGTTGGCTTGCAAGCAAATCGGAACACA TTTGCAGAGCAACCATCCACTGTGGGTTATGCAAGACAAATCATTAAGAAGGAAGGCTGGGGACTCCAGGGCCTCAACAAAGGATTAACT GCAACTTTGGGACGACATGGAGTTTTCAACATGGTTTATTTTGGCTTCTACTACAATGTCAAAAACATGATTCCTGTCAATAAGGATCCA ATCTTGGAGTTTTGGAGAAAATTTGGGATTGGTCTTCTCTCGGGGACAATAGCCTCAGTCATTAACATCCCTTTTGATGTTGCCAAAAGT AGGATTCAAGGGCCTCAACCAGTTCCTGGAGAGATCAAGTACAGAACCTGTTTTAAAACAATGGCAACAGTCTATCAGGAAGAAGGGATT TTAGCTTTGTACAAAGGCCTGCTTCCCAAGATTATGAGACTTGGACCAGGTGGTGCAGTGATGCTGCTGGTTTATGAATACACCTATTCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FOXN3_ENST00000261302_chr14_89656728_-_SLC25A21_ENST00000555449_chr14_37344209_-_1707nt AGGAGCCTTCACGTAAATGGGTCCAGTCATGCCTCCCAGTAAGAAGCCAGAAAGCTCAGGAATTAGTGTCTCCAGTGGACTGAGTCAGTG TTACGGGGGCAGCGGTTTCTCCAAGGCCCTTCAGGAAGACGATGACCTCGACTTTTCTCTGCCTGACATCCGATTAGAAGAGGGGGCCAT GGAAGATGAAGAGCTGACCAACCTGAACTGGCTGCACGAGAGCAAGAACTTGCTGAAGAGCTTTGGGGAGTCGGTCCTCAGGAGTGTCAG CCCCGTCCAGGACCTGGACGATGACACCCCCCCATCCCCTGCCCACTCTGACATGCCCTACGATGCCAGGCAGAACCCCAACTGCAAACC CCCCTACTCCTTCAGCTGCCTCATATTTATGGCCATCGAGGACTCTCCAACCAAGCGCCTGCCAGTGAAGGATATCTACAACTGGATCTT GGAACATTTTCCGTATTTTGCAAATGCACCTACTGGGTGGAAAAACTCAGTGAGACACAATTTATCATTGAATAAGTGTTTTAAGAAAGT GGACAAAGAGAGGAGTCAGAGTATTGGGAAAGGGTCGTTGTGGTGCATAGACCCAGAGTATAGACAAAATCTAATTCAGGCTTTGAAAAA GACACCTTATCACCCACACCCACACGTGTTCAATACACCTCCCACCTGTCCTCAGGCATATCAAAGCACATCAGGTCCACCCATCTGGCC GGGCAGTACCTTCTTCAAGAGAAATGGAGCCCTTCTCCAAGATCCTGACATTGATGCTGCCAGTGCCATGATGCTTTTGAATACTCCCCC TGAGATACAAGCAGGTTGTCTTGTAGAAATTTGCCTGATGCACCCCCTAGATGTGGTGAAAACCAGGTTTCAGATTCAGAGATGTGCAAC CGATCCAAACAGTTATAAAAGCTTGGTAGACAGCTTTCGAATGATTTTCCAAATGGAAGGGTTATTTGGTTTTTACAAGGGAATTCTGCC ACCTATCTTGGCTGAAACCCCAAAAAGAGCAGTGAAGTTTTTCACCTTTGAGCAGTACAAGAAATTGCTGGGATATGTGTCACTGTCACC AGCATTGACATTCGCCATTGCTGGATTGGGATCTGGACTAACAGAAGCCATTGTAGTTAACCCTTTTGAGGTAGTAAAAGTTGGCTTGCA AGCAAATCGGAACACATTTGCAGAGCAACCATCCACTGTGGGTTATGCAAGACAAATCATTAAGAAGGAAGGCTGGGGACTCCAGGGCCT CAACAAAGGATTAACTGCAACTTTGGGACGACATGGAGTTTTCAACATGGTTTATTTTGGCTTCTACTACAATGTCAAAAACATGATTCC TGTCAATAAGGATCCAATCTTGGAGTTTTGGAGAAAATTTGGGATTGGTCTTCTCTCGGGGACAATAGCCTCAGTCATTAACATCCCTTT TGATGTTGCCAAAAGTAGGATTCAAGGGCCTCAACCAGTTCCTGGAGAGATCAAGTACAGAACCTGTTTTAAAACAATGGCAACAGTCTA TCAGGAAGAAGGGATTTTAGCTTTGTACAAAGGCCTGCTTCCCAAGATTATGAGACTTGGACCAGGTGGTGCAGTGATGCTGCTGGTTTA >In-frame_FOXN3_ENST00000261302_chr14_89656728_-_SLC25A21_ENST00000331299_chr14_37344209_-_3026nt AGGAGCCTTCACGTAAATGGGTCCAGTCATGCCTCCCAGTAAGAAGCCAGAAAGCTCAGGAATTAGTGTCTCCAGTGGACTGAGTCAGTG TTACGGGGGCAGCGGTTTCTCCAAGGCCCTTCAGGAAGACGATGACCTCGACTTTTCTCTGCCTGACATCCGATTAGAAGAGGGGGCCAT GGAAGATGAAGAGCTGACCAACCTGAACTGGCTGCACGAGAGCAAGAACTTGCTGAAGAGCTTTGGGGAGTCGGTCCTCAGGAGTGTCAG CCCCGTCCAGGACCTGGACGATGACACCCCCCCATCCCCTGCCCACTCTGACATGCCCTACGATGCCAGGCAGAACCCCAACTGCAAACC CCCCTACTCCTTCAGCTGCCTCATATTTATGGCCATCGAGGACTCTCCAACCAAGCGCCTGCCAGTGAAGGATATCTACAACTGGATCTT GGAACATTTTCCGTATTTTGCAAATGCACCTACTGGGTGGAAAAACTCAGTGAGACACAATTTATCATTGAATAAGTGTTTTAAGAAAGT GGACAAAGAGAGGAGTCAGAGTATTGGGAAAGGGTCGTTGTGGTGCATAGACCCAGAGTATAGACAAAATCTAATTCAGGCTTTGAAAAA GACACCTTATCACCCACACCCACACGTGTTCAATACACCTCCCACCTGTCCTCAGGCATATCAAAGCACATCAGGTCCACCCATCTGGCC GGGCAGTACCTTCTTCAAGAGAAATGGAGCCCTTCTCCAAGATCCTGACATTGATGCTGCCAGTGCCATGATGCTTTTGAATACTCCCCC TGAGATACAAGCAGGTTGTCTTGTAGAAATTTGCCTGATGCACCCCCTAGATGTGGTGAAAACCAGGTTTCAGATTCAGAGATGTGCAAC CGATCCAAACAGTTATAAAAGCTTGGTAGACAGCTTTCGAATGATTTTCCAAATGGAAGGGTTATTTGGTTTTTACAAGGGAATTCTGCC ACCTATCTTGGCTGAAACCCCAAAAAGAGCAGTGAAGTTTTTCACCTTTGAGCAGTACAAGAAATTGCTGGGATATGTGTCACTGTCACC AGCATTGACATTCGCCATTGCTGGATTGGGATCTGGACTAACAGAAGCCATTGTAGTTAACCCTTTTGAGGTAGTAAAAGTTGGCTTGCA AGCAAATCGGAACACATTTGCAGAGCAACCATCCACTGTGGGTTATGCAAGACAAATCATTAAGAAGGAAGGCTGGGGACTCCAGGGCCT CAACAAAGGATTAACTGCAACTTTGGGACGACATGGAGTTTTCAACATGGTTTATTTTGGCTTCTACTACAATGTCAAAAACATGATTCC TGTCAATAAGGATCCAATCTTGGAGTTTTGGAGAAAATTTGGGATTGGTCTTCTCTCGGGGACAATAGCCTCAGTCATTAACATCCCTTT TGATGTTGCCAAAAGTAGGATTCAAGGGCCTCAACCAGTTCCTGGAGAGATCAAGTACAGAACCTGTTTTAAAACAATGGCAACAGTCTA TCAGGAAGAAGGGATTTTAGCTTTGTACAAAGGCCTGCTTCCCAAGATTATGAGACTTGGACCAGGTGGTGCAGTGATGCTGCTGGTTTA TGAATACACCTATTCATGGCTTCAAGAGAACTGGTGATTGCCTATGAAGTGTTTTTCCCCCTTGAGATAATGGATATTTGCTATGCAGCA CCATGAAGAAGAGAGACTATCGATCGGCCAGGTGTATAATTATGAAGGAGAAAACTGTTCAAGAACAAAATCTATTTTAATACTTTAAAA AATGTCTATAGGCAACTTGAGATTATAGTTTTGGCTGTATAAATAAAACTGTGAGAAGAAAAAAATAATATGAAACAATGAGGTATTTAA AGTGAATATAGAAAAATAGCATAGAAATCATATATTTATTTCATAAAATAAATAGAAACTTTGTCTCCTGTGTTCCTCTTCAATGCTTCA CAATGAAAATTCATTGTATTGATCAGCATTTTTCCTAAGAGGTCTAGAAATGCTTAAACTATTGAAAATAAATCAAATTATTCAAAGACT GGATTAAAAAAAAGTTAAGCCAAAATTTAAGCAGTTTTTATAATGAATTAAATTATTCCATAAATAATATTTAAAGAGCACAAGAAAAAT TTTTTAAAGTGCACTAAAATGACCTTTTAAGAATGTTTAATTTTATGAATACTATGTTAAAATGTAAATCTGTTGGTTTTTTTTAGTAAC TATGCACATATCAGCTCTATTTTCCTACATCTACTTTATATCTCATATTGCTGTAAGATAATAAATAGGTATTTTAAAACATTGTTTAAA ACAGAATGTTAAAACACTGTTGTTTAAGCATGTTTAAATCAAGGTATTCCAAATCTCTTCTAACACAAGTAGGAAACATGAAATAAAATT TACTTTCCTCCACATAGTTCTCTTTGAAGATAAGTTTTGTTGATGAGATATTGTCATGTTAAATCACAAATTGGAAACACCTTTGGACCC ATTTGTCAGCCATCAGTATTTGCATCCAAATACCTTTATTCAGCATGCCTACCTGTGCCATTTTTAGGAAGAATGTATAGAACAGAACTG CATTTTCAGGTTATTAGTTTTAAACGACAACTTCAGGTGGGAAGTCAGCTGTCTGCAGTATTAAAATATGTATGATGAAGGGGAAATGTT CTGAAAAAGAAATACACTTAGCATTTCTAAGGATTACTATACTAACATGTATCAACAAAAATATCTCCTTGGTCTTGATGTAACCAAACT TGATTTTATATCTGCATCCAGAGATGATGCTGATTCAGTAAAGTCAACAAGAATAACTGAAAGTCCATATGACACCTGTCCTAAGTTACT ACCGTGGGCTATTTCTACTACGGGGCTATTTCACTAAAGCATTTTGAAAATAAAAAGTAAAAGATAACATGGTAATTATTACTTTTTATT |
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FusionGenePPI for FOXN3_SLC25A21 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FOXN3 | MEN1, ELAVL1, EXOSC8, SRPK2, CHSY3, CHSY1, FOXO3B, HRNR, KBTBD7, FOXR2, RFX2, RFX3, RFX1, ZBTB34, BTRC, FBXW11, DDB2 | SLC25A21 | FBXO6, TBX20, NOSIP, DNASE1L2, PPIE |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FOXN3_SLC25A21 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FOXN3_SLC25A21 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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