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Fusion gene ID: 13623 |
FusionGeneSummary for FMO2_MROH9 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FMO2_MROH9 | Fusion gene ID: 13623 | Hgene | Tgene | Gene symbol | FMO2 | MROH9 | Gene ID | 2329 | 80133 |
| Gene name | flavin containing monooxygenase 4 | maestro heat like repeat family member 9 | |
| Synonyms | FMO2 | ARMC11|C1orf129 | |
| Cytomap | 1q24.3 | 1q24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | dimethylaniline monooxygenase [N-oxide-forming] 4FMO 4dimethylaniline oxidase 4hepatic flavin-containing monooxygenase 4 | maestro heat-like repeat-containing protein family member 9armadillo repeat containing 11 | |
| Modification date | 20180523 | 20180329 | |
| UniProtAcc | Q99518 | Q5TGP6 | |
| Ensembl transtripts involved in fusion gene | ENST00000209929, ENST00000441535, ENST00000529935, | ENST00000367759, ENST00000367758, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 2 X 2 X 2=8 |
| # samples | 2 | 2 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: FMO2 [Title/Abstract] AND MROH9 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | CESC | TCGA-FU-A23L-01A | FMO2 | chr1 | 171174773 | + | MROH9 | chr1 | 171031273 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000209929 | ENST00000367759 | FMO2 | chr1 | 171174773 | + | MROH9 | chr1 | 171031273 | + |
| 5CDS-intron | ENST00000209929 | ENST00000367758 | FMO2 | chr1 | 171174773 | + | MROH9 | chr1 | 171031273 | + |
| In-frame | ENST00000441535 | ENST00000367759 | FMO2 | chr1 | 171174773 | + | MROH9 | chr1 | 171031273 | + |
| 5CDS-intron | ENST00000441535 | ENST00000367758 | FMO2 | chr1 | 171174773 | + | MROH9 | chr1 | 171031273 | + |
| 3UTR-3CDS | ENST00000529935 | ENST00000367759 | FMO2 | chr1 | 171174773 | + | MROH9 | chr1 | 171031273 | + |
| 3UTR-intron | ENST00000529935 | ENST00000367758 | FMO2 | chr1 | 171174773 | + | MROH9 | chr1 | 171031273 | + |
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FusionProtFeatures for FMO2_MROH9 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FMO2 | MROH9 |
| Catalyzes the N-oxidation of certain primary alkylaminesto their oximes via an N-hydroxylamine intermediate. Inactivetoward certain tertiary amines, such as imipramine orchloropromazine. Can catalyze the S-oxidation of methimazole. Thetruncated form is catalytically inactive.{ECO:0000269|PubMed:9804831}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | FMO2 | chr1:171174773 | chr1:171031273 | ENST00000209929 | + | 7 | 9 | 195_198 | 394 | 472 | Nucleotide binding | NADP |
| Hgene | FMO2 | chr1:171174773 | chr1:171031273 | ENST00000209929 | + | 7 | 9 | 40_41 | 394 | 472 | Nucleotide binding | FAD |
| Hgene | FMO2 | chr1:171174773 | chr1:171031273 | ENST00000209929 | + | 7 | 9 | 60_61 | 394 | 472 | Nucleotide binding | NADP |
| Hgene | FMO2 | chr1:171174773 | chr1:171031273 | ENST00000209929 | + | 7 | 9 | 61_62 | 394 | 472 | Nucleotide binding | FAD |
| Hgene | FMO2 | chr1:171174773 | chr1:171031273 | ENST00000209929 | + | 7 | 9 | 9_13 | 394 | 472 | Nucleotide binding | FAD |
| Hgene | FMO2 | chr1:171174773 | chr1:171031273 | ENST00000441535 | + | 7 | 10 | 195_198 | 394 | 1030 | Nucleotide binding | NADP |
| Hgene | FMO2 | chr1:171174773 | chr1:171031273 | ENST00000441535 | + | 7 | 10 | 40_41 | 394 | 1030 | Nucleotide binding | FAD |
| Hgene | FMO2 | chr1:171174773 | chr1:171031273 | ENST00000441535 | + | 7 | 10 | 60_61 | 394 | 1030 | Nucleotide binding | NADP |
| Hgene | FMO2 | chr1:171174773 | chr1:171031273 | ENST00000441535 | + | 7 | 10 | 61_62 | 394 | 1030 | Nucleotide binding | FAD |
| Hgene | FMO2 | chr1:171174773 | chr1:171031273 | ENST00000441535 | + | 7 | 10 | 9_13 | 394 | 1030 | Nucleotide binding | FAD |
| Tgene | >MROH9 | chr1:171174773 | chr1:171031273 | ENST00000367758 | + | 0 | 15 | 118_155 | -33 | 574 | Repeat | Note=HEAT 1 |
| Tgene | >MROH9 | chr1:171174773 | chr1:171031273 | ENST00000367758 | + | 0 | 15 | 252_289 | -33 | 574 | Repeat | Note=HEAT 2 |
| Tgene | >MROH9 | chr1:171174773 | chr1:171031273 | ENST00000367758 | + | 0 | 15 | 292_328 | -33 | 574 | Repeat | Note=HEAT 3 |
| Tgene | >MROH9 | chr1:171174773 | chr1:171031273 | ENST00000367758 | + | 0 | 15 | 357_394 | -33 | 574 | Repeat | Note=HEAT 4 |
| Tgene | >MROH9 | chr1:171174773 | chr1:171031273 | ENST00000367758 | + | 0 | 15 | 418_458 | -33 | 574 | Repeat | Note=HEAT 5 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | MROH9 | chr1:171174773 | chr1:171031273 | ENST00000367759 | + | 19 | 22 | 118_155 | 760 | 862 | Repeat | Note=HEAT 1 |
| Tgene | MROH9 | chr1:171174773 | chr1:171031273 | ENST00000367759 | + | 19 | 22 | 252_289 | 760 | 862 | Repeat | Note=HEAT 2 |
| Tgene | MROH9 | chr1:171174773 | chr1:171031273 | ENST00000367759 | + | 19 | 22 | 292_328 | 760 | 862 | Repeat | Note=HEAT 3 |
| Tgene | MROH9 | chr1:171174773 | chr1:171031273 | ENST00000367759 | + | 19 | 22 | 357_394 | 760 | 862 | Repeat | Note=HEAT 4 |
| Tgene | MROH9 | chr1:171174773 | chr1:171031273 | ENST00000367759 | + | 19 | 22 | 418_458 | 760 | 862 | Repeat | Note=HEAT 5 |
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FusionGeneSequence for FMO2_MROH9 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FMO2_ENST00000209929_chr1_171174773_+_MROH9_ENST00000367759_chr1_171031273_+_496aa MAKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVTNTSKEMSCFSDFPMPEDFPNFLHNSKLLEY FRIFAKKFDLLKYIQFQTTVLSVRKCPDFSSSGQWKVVTQSNGKEQSAVFDAVMVCSGHHILPHIPLKSFPGMERFKGQYFHSRQYKHPD GFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFRSMLRNVLPRTAVKWMIEQQMNRWFNHENYG LEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIFPAH LDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGYLAKSGGHLLLRDEIEVMLDVIERLLRDEDPMIKQLAEITYDIFKKKAHKLTSAP >In-frame_FMO2_ENST00000441535_chr1_171174773_+_MROH9_ENST00000367759_chr1_171031273_+_496aa MAKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVTNTSKEMSCFSDFPMPEDFPNFLHNSKLLEY FRIFAKKFDLLKYIQFQTTVLSVRKCPDFSSSGQWKVVTQSNGKEQSAVFDAVMVCSGHHILPHIPLKSFPGMERFKGQYFHSRQYKHPD GFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFRSMLRNVLPRTAVKWMIEQQMNRWFNHENYG LEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIFPAH LDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGYLAKSGGHLLLRDEIEVMLDVIERLLRDEDPMIKQLAEITYDIFKKKAHKLTSAP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FMO2_ENST00000209929_chr1_171174773_+_MROH9_ENST00000367759_chr1_171031273_+_1488nt ATGGCAAAGAAGGTAGCTGTGATTGGAGCTGGGGTCAGTGGCCTAATTTCTCTGAAGTGCTGTGTGGATGAGGGACTTGAGCCCACTTGC TTTGAGAGAACTGAAGATATTGGAGGAGTGTGGAGGTTCAAAGAGAATGTGGAAGATGGCCGAGCAAGTATCTATCAATCTGTCGTTACC AACACCAGCAAAGAAATGTCCTGTTTCAGTGACTTTCCAATGCCTGAAGATTTTCCAAACTTCCTGCATAATTCTAAACTTCTGGAATAT TTCAGGATTTTTGCTAAAAAATTTGATCTGCTAAAATATATTCAGTTCCAGACAACTGTCCTTAGTGTGAGAAAATGTCCAGATTTCTCA TCCTCTGGCCAATGGAAGGTTGTCACTCAGAGCAACGGCAAGGAGCAGAGTGCTGTCTTTGACGCAGTTATGGTTTGCAGTGGCCACCAC ATTCTACCTCATATCCCACTGAAGTCATTTCCAGGTATGGAGAGGTTCAAAGGCCAATATTTCCATAGCCGCCAATACAAGCATCCAGAT GGATTTGAGGGAAAACGCATCCTGGTGATTGGAATGGGAAACTCAGGCTCAGATATTGCTGTTGAGCTGAGTAAGAATGCTGCTCAGGTT TTTATCAGCACCAGGCATGGCACCTGGGTCATGAGCCGTATCTCTGAAGATGGCTATCCTTGGGACTCAGTGTTCCACACCCGGTTTCGT TCTATGCTCCGCAATGTACTGCCACGAACAGCTGTAAAATGGATGATAGAACAACAGATGAATCGGTGGTTCAACCATGAAAATTATGGC CTTGAGCCTCAAAACAAATACATTATGAAGGAACCTGTACTAAATGATGATGTCCCAAGTCGTCTACTCTGTGGAGCCATCAAGGTGAAA TCTACAGTGAAAGAGCTCACAGAAACTTCTGCCATCTTTGAGGATGGAACAGTGGAGGAGAACATTGATGTCATCATTTTTGCAACAGGA TATAGTTTCTCTTTTCCCTTCCTTGAAGATTCACTCGTTAAAGTAGAGAATAATATGGTCTCACTGTATAAATACATATTCCCCGCTCAC CTGGACAAGTCAACCCTCGCGTGCATTGGTCTCATCCAGCCCCTAGGTTCCATTTTCCCAACTGCTGAACTTCAAGCTCGTTGGGTGACA AGAGTTTTCAAAGGATATTTGGCAAAATCAGGTGGTCATTTACTGCTTAGAGATGAAATCGAAGTCATGCTTGATGTTATTGAACGACTG CTCCGAGATGAAGACCCTATGATCAAACAGTTGGCTGAAATAACCTATGATATTTTTAAGAAAAAAGCCCATAAACTGACCTCTGCACCT CTTAAACAAAACTTCCAAAAATTGCTTAAATTATTCTACATCAAAAAATTGAAGCCTCTTTACAATTATAACTCACCCAATGGCCAGATA >In-frame_FMO2_ENST00000441535_chr1_171174773_+_MROH9_ENST00000367759_chr1_171031273_+_1488nt ATGGCAAAGAAGGTAGCTGTGATTGGAGCTGGGGTCAGTGGCCTAATTTCTCTGAAGTGCTGTGTGGATGAGGGACTTGAGCCCACTTGC TTTGAGAGAACTGAAGATATTGGAGGAGTGTGGAGGTTCAAAGAGAATGTGGAAGATGGCCGAGCAAGTATCTATCAATCTGTCGTTACC AACACCAGCAAAGAAATGTCCTGTTTCAGTGACTTTCCAATGCCTGAAGATTTTCCAAACTTCCTGCATAATTCTAAACTTCTGGAATAT TTCAGGATTTTTGCTAAAAAATTTGATCTGCTAAAATATATTCAGTTCCAGACAACTGTCCTTAGTGTGAGAAAATGTCCAGATTTCTCA TCCTCTGGCCAATGGAAGGTTGTCACTCAGAGCAACGGCAAGGAGCAGAGTGCTGTCTTTGACGCAGTTATGGTTTGCAGTGGCCACCAC ATTCTACCTCATATCCCACTGAAGTCATTTCCAGGTATGGAGAGGTTCAAAGGCCAATATTTCCATAGCCGCCAATACAAGCATCCAGAT GGATTTGAGGGAAAACGCATCCTGGTGATTGGAATGGGAAACTCAGGCTCAGATATTGCTGTTGAGCTGAGTAAGAATGCTGCTCAGGTT TTTATCAGCACCAGGCATGGCACCTGGGTCATGAGCCGTATCTCTGAAGATGGCTATCCTTGGGACTCAGTGTTCCACACCCGGTTTCGT TCTATGCTCCGCAATGTACTGCCACGAACAGCTGTAAAATGGATGATAGAACAACAGATGAATCGGTGGTTCAACCATGAAAATTATGGC CTTGAGCCTCAAAACAAATACATTATGAAGGAACCTGTACTAAATGATGATGTCCCAAGTCGTCTACTCTGTGGAGCCATCAAGGTGAAA TCTACAGTGAAAGAGCTCACAGAAACTTCTGCCATCTTTGAGGATGGAACAGTGGAGGAGAACATTGATGTCATCATTTTTGCAACAGGA TATAGTTTCTCTTTTCCCTTCCTTGAAGATTCACTCGTTAAAGTAGAGAATAATATGGTCTCACTGTATAAATACATATTCCCCGCTCAC CTGGACAAGTCAACCCTCGCGTGCATTGGTCTCATCCAGCCCCTAGGTTCCATTTTCCCAACTGCTGAACTTCAAGCTCGTTGGGTGACA AGAGTTTTCAAAGGATATTTGGCAAAATCAGGTGGTCATTTACTGCTTAGAGATGAAATCGAAGTCATGCTTGATGTTATTGAACGACTG CTCCGAGATGAAGACCCTATGATCAAACAGTTGGCTGAAATAACCTATGATATTTTTAAGAAAAAAGCCCATAAACTGACCTCTGCACCT CTTAAACAAAACTTCCAAAAATTGCTTAAATTATTCTACATCAAAAAATTGAAGCCTCTTTACAATTATAACTCACCCAATGGCCAGATA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FMO2_ENST00000209929_chr1_171174773_+_MROH9_ENST00000367759_chr1_171031273_+_2071nt TTCAGCTGGAAGAATGCTGGAGGAATACGGAACTCCTCCCATTTCTCACAGCCACCTCCAACTCTTAAAAACGCTTCCAACTGCCTCCCA GCACACAACCAAGGGAGAAAACTATTCTGTCAAAGAGACGGTGCCAAAAGGCAAAAACAAAGGAGCTGATGGCAAAGAAGGTAGCTGTGA TTGGAGCTGGGGTCAGTGGCCTAATTTCTCTGAAGTGCTGTGTGGATGAGGGACTTGAGCCCACTTGCTTTGAGAGAACTGAAGATATTG GAGGAGTGTGGAGGTTCAAAGAGAATGTGGAAGATGGCCGAGCAAGTATCTATCAATCTGTCGTTACCAACACCAGCAAAGAAATGTCCT GTTTCAGTGACTTTCCAATGCCTGAAGATTTTCCAAACTTCCTGCATAATTCTAAACTTCTGGAATATTTCAGGATTTTTGCTAAAAAAT TTGATCTGCTAAAATATATTCAGTTCCAGACAACTGTCCTTAGTGTGAGAAAATGTCCAGATTTCTCATCCTCTGGCCAATGGAAGGTTG TCACTCAGAGCAACGGCAAGGAGCAGAGTGCTGTCTTTGACGCAGTTATGGTTTGCAGTGGCCACCACATTCTACCTCATATCCCACTGA AGTCATTTCCAGGTATGGAGAGGTTCAAAGGCCAATATTTCCATAGCCGCCAATACAAGCATCCAGATGGATTTGAGGGAAAACGCATCC TGGTGATTGGAATGGGAAACTCAGGCTCAGATATTGCTGTTGAGCTGAGTAAGAATGCTGCTCAGGTTTTTATCAGCACCAGGCATGGCA CCTGGGTCATGAGCCGTATCTCTGAAGATGGCTATCCTTGGGACTCAGTGTTCCACACCCGGTTTCGTTCTATGCTCCGCAATGTACTGC CACGAACAGCTGTAAAATGGATGATAGAACAACAGATGAATCGGTGGTTCAACCATGAAAATTATGGCCTTGAGCCTCAAAACAAATACA TTATGAAGGAACCTGTACTAAATGATGATGTCCCAAGTCGTCTACTCTGTGGAGCCATCAAGGTGAAATCTACAGTGAAAGAGCTCACAG AAACTTCTGCCATCTTTGAGGATGGAACAGTGGAGGAGAACATTGATGTCATCATTTTTGCAACAGGATATAGTTTCTCTTTTCCCTTCC TTGAAGATTCACTCGTTAAAGTAGAGAATAATATGGTCTCACTGTATAAATACATATTCCCCGCTCACCTGGACAAGTCAACCCTCGCGT GCATTGGTCTCATCCAGCCCCTAGGTTCCATTTTCCCAACTGCTGAACTTCAAGCTCGTTGGGTGACAAGAGTTTTCAAAGGATATTTGG CAAAATCAGGTGGTCATTTACTGCTTAGAGATGAAATCGAAGTCATGCTTGATGTTATTGAACGACTGCTCCGAGATGAAGACCCTATGA TCAAACAGTTGGCTGAAATAACCTATGATATTTTTAAGAAAAAAGCCCATAAACTGACCTCTGCACCTCTTAAACAAAACTTCCAAAAAT TGCTTAAATTATTCTACATCAAAAAATTGAAGCCTCTTTACAATTATAACTCACCCAATGGCCAGATAGACAGTCCTACAGACAGTAAAG ATGTCAAGAATGATAAGGCCTTATAGAAGAGAATGATGATGACATTCATCATTCATAAACAATGGGAAGTCCAACAATGTCTTGGAGCTG ACCTTAGAAGAAGAATGATTTTTCTTTCCCTCCTGACAACTTGAGTCTGTTTGTAGATGCTTTTCTGAAAAATTCTGGAAGCTTTTACTG TTACTTCTTAATTCTCTATTCAAATATAGAAATCTGAGAGAACTAGTGCCTCTGTATGTCTGACAGTGATCAGAAGCCCTATTTCATCAA AACCACTAAGACAATTGAAAATAACATAAGCAAAGTGTTTGATGAGAAGCTCTGGGAACTTGATTCAGTCCGGAAGCTCTACTGAGCACC TTCTAAGTGCCAGATACTGTGTTAGGCAGTGGGGACATTTGGATGATATAGACAAGGTTCCTGATCTCAGGATGGGCACAGTCTAGTGAC >In-frame_FMO2_ENST00000441535_chr1_171174773_+_MROH9_ENST00000367759_chr1_171031273_+_2030nt TTTCTCACAGCCACCTCCAACTCTTAAAAACGCTTCCAACTGCCTCCCAGCACACAACCAAGGGAGAAAACTATTCTGTCAAAGAGACGG TGCCAAAAGGCAAAAACAAAGGAGCTGATGGCAAAGAAGGTAGCTGTGATTGGAGCTGGGGTCAGTGGCCTAATTTCTCTGAAGTGCTGT GTGGATGAGGGACTTGAGCCCACTTGCTTTGAGAGAACTGAAGATATTGGAGGAGTGTGGAGGTTCAAAGAGAATGTGGAAGATGGCCGA GCAAGTATCTATCAATCTGTCGTTACCAACACCAGCAAAGAAATGTCCTGTTTCAGTGACTTTCCAATGCCTGAAGATTTTCCAAACTTC CTGCATAATTCTAAACTTCTGGAATATTTCAGGATTTTTGCTAAAAAATTTGATCTGCTAAAATATATTCAGTTCCAGACAACTGTCCTT AGTGTGAGAAAATGTCCAGATTTCTCATCCTCTGGCCAATGGAAGGTTGTCACTCAGAGCAACGGCAAGGAGCAGAGTGCTGTCTTTGAC GCAGTTATGGTTTGCAGTGGCCACCACATTCTACCTCATATCCCACTGAAGTCATTTCCAGGTATGGAGAGGTTCAAAGGCCAATATTTC CATAGCCGCCAATACAAGCATCCAGATGGATTTGAGGGAAAACGCATCCTGGTGATTGGAATGGGAAACTCAGGCTCAGATATTGCTGTT GAGCTGAGTAAGAATGCTGCTCAGGTTTTTATCAGCACCAGGCATGGCACCTGGGTCATGAGCCGTATCTCTGAAGATGGCTATCCTTGG GACTCAGTGTTCCACACCCGGTTTCGTTCTATGCTCCGCAATGTACTGCCACGAACAGCTGTAAAATGGATGATAGAACAACAGATGAAT CGGTGGTTCAACCATGAAAATTATGGCCTTGAGCCTCAAAACAAATACATTATGAAGGAACCTGTACTAAATGATGATGTCCCAAGTCGT CTACTCTGTGGAGCCATCAAGGTGAAATCTACAGTGAAAGAGCTCACAGAAACTTCTGCCATCTTTGAGGATGGAACAGTGGAGGAGAAC ATTGATGTCATCATTTTTGCAACAGGATATAGTTTCTCTTTTCCCTTCCTTGAAGATTCACTCGTTAAAGTAGAGAATAATATGGTCTCA CTGTATAAATACATATTCCCCGCTCACCTGGACAAGTCAACCCTCGCGTGCATTGGTCTCATCCAGCCCCTAGGTTCCATTTTCCCAACT GCTGAACTTCAAGCTCGTTGGGTGACAAGAGTTTTCAAAGGATATTTGGCAAAATCAGGTGGTCATTTACTGCTTAGAGATGAAATCGAA GTCATGCTTGATGTTATTGAACGACTGCTCCGAGATGAAGACCCTATGATCAAACAGTTGGCTGAAATAACCTATGATATTTTTAAGAAA AAAGCCCATAAACTGACCTCTGCACCTCTTAAACAAAACTTCCAAAAATTGCTTAAATTATTCTACATCAAAAAATTGAAGCCTCTTTAC AATTATAACTCACCCAATGGCCAGATAGACAGTCCTACAGACAGTAAAGATGTCAAGAATGATAAGGCCTTATAGAAGAGAATGATGATG ACATTCATCATTCATAAACAATGGGAAGTCCAACAATGTCTTGGAGCTGACCTTAGAAGAAGAATGATTTTTCTTTCCCTCCTGACAACT TGAGTCTGTTTGTAGATGCTTTTCTGAAAAATTCTGGAAGCTTTTACTGTTACTTCTTAATTCTCTATTCAAATATAGAAATCTGAGAGA ACTAGTGCCTCTGTATGTCTGACAGTGATCAGAAGCCCTATTTCATCAAAACCACTAAGACAATTGAAAATAACATAAGCAAAGTGTTTG ATGAGAAGCTCTGGGAACTTGATTCAGTCCGGAAGCTCTACTGAGCACCTTCTAAGTGCCAGATACTGTGTTAGGCAGTGGGGACATTTG |
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FusionGenePPI for FMO2_MROH9 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FMO2 | GNB2 | MROH9 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FMO2_MROH9 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FMO2_MROH9 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | FMO2 | C0014175 | Endometriosis | 1 | CTD_human |
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