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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 13590

FusionGeneSummary for FLT1_CTNND1

check button Fusion gene summary
Fusion gene informationFusion gene name: FLT1_CTNND1
Fusion gene ID: 13590
HgeneTgene
Gene symbol

FLT1

CTNND1

Gene ID

2321

1500

Gene namefms related tyrosine kinase 1catenin delta 1
SynonymsFLT|FLT-1|VEGFR-1|VEGFR1BCDS2|CAS|CTNND|P120CAS|P120CTN|p120|p120(CAS)|p120(CTN)
Cytomap

13q12.3

11q12.1

Type of geneprotein-codingprotein-coding
Descriptionvascular endothelial growth factor receptor 1fms-like tyrosine kinase 1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)tyrosine-protein kinase FRTtyrosine-protein kinase receptor FLTvascular percatenin delta-1cadherin-associated Src substratecatenin (cadherin-associated protein), delta 1p120 catenin
Modification date2018052720180523
UniProtAcc

P17948

O60716

Ensembl transtripts involved in fusion geneENST00000282397, ENST00000541932, 
ENST00000543394, ENST00000540678, 
ENST00000539099, 
ENST00000524630, 
ENST00000529919, ENST00000399039, 
ENST00000360682, ENST00000361796, 
ENST00000361391, ENST00000530094, 
ENST00000428599, ENST00000361332, 
ENST00000527467, ENST00000415361, 
ENST00000532245, ENST00000532463, 
ENST00000528232, ENST00000529986, 
ENST00000531014, ENST00000358694, 
ENST00000526772, ENST00000532787, 
ENST00000533667, ENST00000529873, 
ENST00000525902, ENST00000529526, 
ENST00000532649, ENST00000426142, 
ENST00000532844, ENST00000528621, 
ENST00000399050, ENST00000526357, 
ENST00000530748, ENST00000534579, 
ENST00000526938, 
Fusion gene scores* DoF score1 X 1 X 1=18 X 7 X 5=280
# samples 19
** MAII scorelog2(1/1*10)=3.32192809488736log2(9/280*10)=-1.63742992061529
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FLT1 [Title/Abstract] AND CTNND1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneFLT1

GO:0002548

monocyte chemotaxis

8605350|18079407

HgeneFLT1

GO:0018108

peptidyl-tyrosine phosphorylation

9299537|11513746

HgeneFLT1

GO:0030335

positive regulation of cell migration

8605350

HgeneFLT1

GO:0030949

positive regulation of vascular endothelial growth factor receptor signaling pathway

1312256

HgeneFLT1

GO:0035924

cellular response to vascular endothelial growth factor stimulus

8605350

HgeneFLT1

GO:0036323

vascular endothelial growth factor receptor-1 signaling pathway

15952180

HgeneFLT1

GO:0043406

positive regulation of MAP kinase activity

9299537

HgeneFLT1

GO:0043410

positive regulation of MAPK cascade

9299537

HgeneFLT1

GO:0046777

protein autophosphorylation

9299537|11513746

HgeneFLT1

GO:0048010

vascular endothelial growth factor receptor signaling pathway

9299537


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1BF351098FLT1chr13

28964014

-CTNND1chr11

57545740

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-intronENST00000282397ENST00000524630FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000529919FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000399039FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000360682FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000361796FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000361391FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000530094FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000428599FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000361332FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000527467FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000415361FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000532245FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000532463FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000528232FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000529986FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000531014FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000358694FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000526772FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000532787FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000533667FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000529873FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000525902FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000529526FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000532649FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000426142FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000532844FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000528621FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000399050FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000526357FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000530748FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000534579FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000282397ENST00000526938FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000524630FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000529919FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000399039FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000360682FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000361796FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000361391FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000530094FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000428599FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000361332FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000527467FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000415361FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000532245FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000532463FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000528232FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000529986FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000531014FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000358694FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000526772FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000532787FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000533667FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000529873FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000525902FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000529526FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000532649FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000426142FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000532844FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000528621FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000399050FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000526357FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000530748FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000534579FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000541932ENST00000526938FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000524630FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000529919FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000399039FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000360682FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000361796FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000361391FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000530094FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000428599FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000361332FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000527467FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000415361FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000532245FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000532463FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000528232FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000529986FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000531014FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000358694FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000526772FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000532787FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000533667FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000529873FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000525902FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000529526FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000532649FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000426142FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000532844FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000528621FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000399050FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000526357FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000530748FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000534579FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000543394ENST00000526938FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000524630FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000529919FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000399039FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000360682FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000361796FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000361391FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000530094FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000428599FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000361332FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000527467FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000415361FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000532245FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000532463FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000528232FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000529986FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000531014FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000358694FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000526772FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000532787FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000533667FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000529873FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000525902FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000529526FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000532649FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000426142FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000532844FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000528621FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000399050FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000526357FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000530748FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000534579FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000540678ENST00000526938FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000524630FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000529919FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000399039FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000360682FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000361796FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000361391FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000530094FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000428599FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000361332FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000527467FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000415361FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000532245FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000532463FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000528232FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000529986FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000531014FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000358694FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000526772FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000532787FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000533667FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000529873FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000525902FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000529526FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000532649FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000426142FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000532844FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000528621FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000399050FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000526357FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000530748FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000534579FLT1chr13

28964014

-CTNND1chr11

57545740

-
intron-intronENST00000539099ENST00000526938FLT1chr13

28964014

-CTNND1chr11

57545740

-

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FusionProtFeatures for FLT1_CTNND1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FLT1

P17948

CTNND1

O60716


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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FusionGeneSequence for FLT1_CTNND1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for FLT1_CTNND1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for FLT1_CTNND1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneFLT1P17948DB06589PazopanibVascular endothelial growth factor receptor 1small moleculeapproved
HgeneFLT1P17948DB08896RegorafenibVascular endothelial growth factor receptor 1small moleculeapproved
HgeneFLT1P17948DB09079NintedanibVascular endothelial growth factor receptor 1small moleculeapproved
HgeneFLT1P17948DB00398SorafenibVascular endothelial growth factor receptor 1small moleculeapproved|investigational
HgeneFLT1P17948DB01268SunitinibVascular endothelial growth factor receptor 1small moleculeapproved|investigational
HgeneFLT1P17948DB06626AxitinibVascular endothelial growth factor receptor 1small moleculeapproved|investigational
HgeneFLT1P17948DB09078LenvatinibVascular endothelial growth factor receptor 1small moleculeapproved|investigational

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RelatedDiseases for FLT1_CTNND1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneFLT1C1458155Mammary Neoplasms2CTD_human
HgeneFLT1C0007134Renal Cell Carcinoma1CTD_human
HgeneFLT1C0018923Hemangiosarcoma1CTD_human
HgeneFLT1C0023890Liver Cirrhosis1CTD_human
HgeneFLT1C0025202melanoma1CTD_human
HgeneFLT1C0027627Neoplasm Metastasis1CTD_human
HgeneFLT1C0029422Osteochondrodysplasias1CTD_human
HgeneFLT1C0032914Pre-Eclampsia1CTD_human
HgeneFLT1C0037286Skin Neoplasms1CTD_human
HgeneFLT1C0041948Uremia1CTD_human
HgeneFLT1C2937358Cerebral Hemorrhage1CTD_human
HgeneFLT1C4277682Chemical and Drug Induced Liver Injury1CTD_human