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Fusion gene ID: 13493 |
FusionGeneSummary for FKBP10_KRT40 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FKBP10_KRT40 | Fusion gene ID: 13493 | Hgene | Tgene | Gene symbol | FKBP10 | KRT40 | Gene ID | 60681 | 125115 |
| Gene name | FK506 binding protein 10 | keratin 40 | |
| Synonyms | BRKS1|FKBP65|OI11|OI6|PPIASE|hFKBP65 | CK-40|K40|KA36 | |
| Cytomap | 17q21.2 | 17q21.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | peptidyl-prolyl cis-trans isomerase FKBP1065 kDa FK506-binding protein65 kDa FKBPFK506 binding protein 10, 65 kDaFKBP-10FKBP-65PPIase FKBP10immunophilin FKBP65rotamase | keratin, type I cytoskeletal 40cytokeratin-40keratin 40, type Itype I hair keratin KA36 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | Q96AY3 | Q6A162 | |
| Ensembl transtripts involved in fusion gene | ENST00000321562, ENST00000544340, | ENST00000377755, ENST00000398486, | |
| Fusion gene scores | * DoF score | 5 X 4 X 3=60 | 3 X 4 X 4=48 |
| # samples | 6 | 4 | |
| ** MAII score | log2(6/60*10)=0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FKBP10 [Title/Abstract] AND KRT40 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | STAD | TCGA-CG-4466-01A | FKBP10 | chr17 | 39969531 | + | KRT40 | chr17 | 39138715 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000321562 | ENST00000377755 | FKBP10 | chr17 | 39969531 | + | KRT40 | chr17 | 39138715 | - |
| In-frame | ENST00000321562 | ENST00000398486 | FKBP10 | chr17 | 39969531 | + | KRT40 | chr17 | 39138715 | - |
| intron-3CDS | ENST00000544340 | ENST00000377755 | FKBP10 | chr17 | 39969531 | + | KRT40 | chr17 | 39138715 | - |
| intron-3CDS | ENST00000544340 | ENST00000398486 | FKBP10 | chr17 | 39969531 | + | KRT40 | chr17 | 39138715 | - |
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FusionProtFeatures for FKBP10_KRT40 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FKBP10 | KRT40 |
| PPIases accelerate the folding of proteins duringprotein synthesis. | May play a role in late hair differentiation. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >KRT40 | chr17:39969531 | chr17:39138715 | ENST00000377755 | - | 1 | 7 | 237_252 | 176 | 432 | Region | Note=Linker 12 |
| Tgene | >KRT40 | chr17:39969531 | chr17:39138715 | ENST00000377755 | - | 1 | 7 | 253_396 | 176 | 432 | Region | Note=Coil 2 |
| Tgene | >KRT40 | chr17:39969531 | chr17:39138715 | ENST00000377755 | - | 1 | 7 | 397_431 | 176 | 432 | Region | Note=Tail |
| Tgene | >KRT40 | chr17:39969531 | chr17:39138715 | ENST00000398486 | - | 3 | 9 | 237_252 | 176 | 432 | Region | Note=Linker 12 |
| Tgene | >KRT40 | chr17:39969531 | chr17:39138715 | ENST00000398486 | - | 3 | 9 | 253_396 | 176 | 432 | Region | Note=Coil 2 |
| Tgene | >KRT40 | chr17:39969531 | chr17:39138715 | ENST00000398486 | - | 3 | 9 | 397_431 | 176 | 432 | Region | Note=Tail |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >FKBP10 | chr17:39969531 | chr17:39138715 | ENST00000321562 | + | 1 | 10 | 510_521 | 81 | 583 | Calcium binding | 1 |
| Hgene | >FKBP10 | chr17:39969531 | chr17:39138715 | ENST00000321562 | + | 1 | 10 | 555_566 | 81 | 583 | Calcium binding | 2 |
| Hgene | >FKBP10 | chr17:39969531 | chr17:39138715 | ENST00000321562 | + | 1 | 10 | 174_262 | 81 | 583 | Domain | PPIase FKBP-type 2 |
| Hgene | >FKBP10 | chr17:39969531 | chr17:39138715 | ENST00000321562 | + | 1 | 10 | 286_374 | 81 | 583 | Domain | PPIase FKBP-type 3 |
| Hgene | >FKBP10 | chr17:39969531 | chr17:39138715 | ENST00000321562 | + | 1 | 10 | 399_486 | 81 | 583 | Domain | PPIase FKBP-type 4 |
| Hgene | >FKBP10 | chr17:39969531 | chr17:39138715 | ENST00000321562 | + | 1 | 10 | 497_532 | 81 | 583 | Domain | EF-hand 1 |
| Hgene | >FKBP10 | chr17:39969531 | chr17:39138715 | ENST00000321562 | + | 1 | 10 | 542_577 | 81 | 583 | Domain | EF-hand 2 |
| Hgene | >FKBP10 | chr17:39969531 | chr17:39138715 | ENST00000321562 | + | 1 | 10 | 62_150 | 81 | 583 | Domain | PPIase FKBP-type 1 |
| Hgene | >FKBP10 | chr17:39969531 | chr17:39138715 | ENST00000321562 | + | 1 | 10 | 579_582 | 81 | 583 | Motif | Prevents secretion from ER |
| Tgene | KRT40 | chr17:39969531 | chr17:39138715 | ENST00000377755 | - | 1 | 7 | 89_400 | 176 | 432 | Domain | IF rod |
| Tgene | KRT40 | chr17:39969531 | chr17:39138715 | ENST00000398486 | - | 3 | 9 | 89_400 | 176 | 432 | Domain | IF rod |
| Tgene | KRT40 | chr17:39969531 | chr17:39138715 | ENST00000377755 | - | 1 | 7 | 125_135 | 176 | 432 | Region | Note=Linker 1 |
| Tgene | KRT40 | chr17:39969531 | chr17:39138715 | ENST00000377755 | - | 1 | 7 | 136_236 | 176 | 432 | Region | Note=Coil 1B |
| Tgene | KRT40 | chr17:39969531 | chr17:39138715 | ENST00000377755 | - | 1 | 7 | 1_89 | 176 | 432 | Region | Note=Head |
| Tgene | KRT40 | chr17:39969531 | chr17:39138715 | ENST00000377755 | - | 1 | 7 | 90_124 | 176 | 432 | Region | Note=Coil 1A |
| Tgene | KRT40 | chr17:39969531 | chr17:39138715 | ENST00000398486 | - | 3 | 9 | 125_135 | 176 | 432 | Region | Note=Linker 1 |
| Tgene | KRT40 | chr17:39969531 | chr17:39138715 | ENST00000398486 | - | 3 | 9 | 136_236 | 176 | 432 | Region | Note=Coil 1B |
| Tgene | KRT40 | chr17:39969531 | chr17:39138715 | ENST00000398486 | - | 3 | 9 | 1_89 | 176 | 432 | Region | Note=Head |
| Tgene | KRT40 | chr17:39969531 | chr17:39138715 | ENST00000398486 | - | 3 | 9 | 90_124 | 176 | 432 | Region | Note=Coil 1A |
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FusionGeneSequence for FKBP10_KRT40 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FKBP10_ENST00000321562_chr17_39969531_+_KRT40_ENST00000377755_chr17_39138715_-_337aa MFPAGPPSHSLLRLPLLQLLLLVVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSRYESELSLR QLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRRE AEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDL >In-frame_FKBP10_ENST00000321562_chr17_39969531_+_KRT40_ENST00000398486_chr17_39138715_-_337aa MFPAGPPSHSLLRLPLLQLLLLVVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSRYESELSLR QLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRRE AEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FKBP10_ENST00000321562_chr17_39969531_+_KRT40_ENST00000377755_chr17_39138715_-_1011nt ATGTTCCCCGCGGGCCCCCCCAGCCACAGCCTCCTCCGGCTCCCCCTGCTGCAGTTGCTGCTACTGGTGGTGCAGGCCGTGGGGAGGGGG CTGGGCCGCGCCAGCCCGGCCGGGGGCCCCCTGGAAGATGTGGTCATCGAGAGGTACCACATCCCCAGGGCCTGTCCCCGGGAAGTGCAG ATGGGGGATTTTGTGCGCTACCACTACAACGGCACTTTTGAAGATGGCAAGAAGTTTGATTCAAGGTACGAGAGTGAACTGTCCCTTCGC CAGCTGTTAGAGGCTGACATCAGCAGCCTGCATGGGATCCTGGAGGAACTGACCCTGTGCAAATCTGATCTGGAGGCCCATGTGGAGTCT CTGAAGGAAGATCTCCTTTGCCTTAAGAAAAACCATGAAGAGGAAGTCAACTTGCTTCGTGAACAGCTTGGCGACCGCCTCAGTGTGGAG CTGGACACTGCCCCCACCCTTGACCTCAACAGGGTCCTGGATGAGATGCGCTGTCAGTGTGAAACGGTGCTTGCCAACAATCGCAGAGAA GCTGAAGAATGGTTGGCTGTTCAGACAGAAGAGCTGAATCAGCAGCAACTGTCCAGCGCGGAGCAGCTGCAGGGCTGCCAGATGGAGATC TTGGAACTGAAACGCACAGCCAGTGCTCTGGAAATTGAGCTCCAAGCACAGCAAAGCCTGACAGAATCTCTGGAATGCACCGTGGCAGAA ACCGAGGCCCAGTACAGCTCCCAGCTGGCCCAAATTCAGTGTCTGATCGATAACCTGGAGAACCAGCTGGCCGAGATCCGCTGCGACCTG GAGCGACAGAACCAGGAGTACCAGGTGCTCCTGGACGTGAAGGCCCGGCTGGAGGGTGAGATCAACACGTACTGGGGCCTGCTGGACAGC GAGGACAGCAGGCTTTCCTGTAGCCCATGTTCGACCACATGCACCTCGAGCAACACTTGTGAGCCATGCTCAGCCTATGTCATCTGCACT >In-frame_FKBP10_ENST00000321562_chr17_39969531_+_KRT40_ENST00000398486_chr17_39138715_-_1011nt ATGTTCCCCGCGGGCCCCCCCAGCCACAGCCTCCTCCGGCTCCCCCTGCTGCAGTTGCTGCTACTGGTGGTGCAGGCCGTGGGGAGGGGG CTGGGCCGCGCCAGCCCGGCCGGGGGCCCCCTGGAAGATGTGGTCATCGAGAGGTACCACATCCCCAGGGCCTGTCCCCGGGAAGTGCAG ATGGGGGATTTTGTGCGCTACCACTACAACGGCACTTTTGAAGATGGCAAGAAGTTTGATTCAAGGTACGAGAGTGAACTGTCCCTTCGC CAGCTGTTAGAGGCTGACATCAGCAGCCTGCATGGGATCCTGGAGGAACTGACCCTGTGCAAATCTGATCTGGAGGCCCATGTGGAGTCT CTGAAGGAAGATCTCCTTTGCCTTAAGAAAAACCATGAAGAGGAAGTCAACTTGCTTCGTGAACAGCTTGGCGACCGCCTCAGTGTGGAG CTGGACACTGCCCCCACCCTTGACCTCAACAGGGTCCTGGATGAGATGCGCTGTCAGTGTGAAACGGTGCTTGCCAACAATCGCAGAGAA GCTGAAGAATGGTTGGCTGTTCAGACAGAAGAGCTGAATCAGCAGCAACTGTCCAGCGCGGAGCAGCTGCAGGGCTGCCAGATGGAGATC TTGGAACTGAAACGCACAGCCAGTGCTCTGGAAATTGAGCTCCAAGCACAGCAAAGCCTGACAGAATCTCTGGAATGCACCGTGGCAGAA ACCGAGGCCCAGTACAGCTCCCAGCTGGCCCAAATTCAGTGTCTGATCGATAACCTGGAGAACCAGCTGGCCGAGATCCGCTGCGACCTG GAGCGACAGAACCAGGAGTACCAGGTGCTCCTGGACGTGAAGGCCCGGCTGGAGGGTGAGATCAACACGTACTGGGGCCTGCTGGACAGC GAGGACAGCAGGCTTTCCTGTAGCCCATGTTCGACCACATGCACCTCGAGCAACACTTGTGAGCCATGCTCAGCCTATGTCATCTGCACT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FKBP10_ENST00000321562_chr17_39969531_+_KRT40_ENST00000377755_chr17_39138715_-_1596nt AGAGGACAGGAAGAGGGGGAGCCAGTTCTGGGAGGCGGGGGGAAGGAGGTTGGTGGCGACTCCCTCGCTCGCCCTCACTGCCGGCGGTCC CAACTCCAGGCACCATGTTCCCCGCGGGCCCCCCCAGCCACAGCCTCCTCCGGCTCCCCCTGCTGCAGTTGCTGCTACTGGTGGTGCAGG CCGTGGGGAGGGGGCTGGGCCGCGCCAGCCCGGCCGGGGGCCCCCTGGAAGATGTGGTCATCGAGAGGTACCACATCCCCAGGGCCTGTC CCCGGGAAGTGCAGATGGGGGATTTTGTGCGCTACCACTACAACGGCACTTTTGAAGATGGCAAGAAGTTTGATTCAAGGTACGAGAGTG AACTGTCCCTTCGCCAGCTGTTAGAGGCTGACATCAGCAGCCTGCATGGGATCCTGGAGGAACTGACCCTGTGCAAATCTGATCTGGAGG CCCATGTGGAGTCTCTGAAGGAAGATCTCCTTTGCCTTAAGAAAAACCATGAAGAGGAAGTCAACTTGCTTCGTGAACAGCTTGGCGACC GCCTCAGTGTGGAGCTGGACACTGCCCCCACCCTTGACCTCAACAGGGTCCTGGATGAGATGCGCTGTCAGTGTGAAACGGTGCTTGCCA ACAATCGCAGAGAAGCTGAAGAATGGTTGGCTGTTCAGACAGAAGAGCTGAATCAGCAGCAACTGTCCAGCGCGGAGCAGCTGCAGGGCT GCCAGATGGAGATCTTGGAACTGAAACGCACAGCCAGTGCTCTGGAAATTGAGCTCCAAGCACAGCAAAGCCTGACAGAATCTCTGGAAT GCACCGTGGCAGAAACCGAGGCCCAGTACAGCTCCCAGCTGGCCCAAATTCAGTGTCTGATCGATAACCTGGAGAACCAGCTGGCCGAGA TCCGCTGCGACCTGGAGCGACAGAACCAGGAGTACCAGGTGCTCCTGGACGTGAAGGCCCGGCTGGAGGGTGAGATCAACACGTACTGGG GCCTGCTGGACAGCGAGGACAGCAGGCTTTCCTGTAGCCCATGTTCGACCACATGCACCTCGAGCAACACTTGTGAGCCATGCTCAGCCT ATGTCATCTGCACTGTTGAAAACTGCTGCTTGTGAATGTTAAGGACAGCAGGTAGAGGAATCAAAGCCAGCAGCATCCTAGAAAGGAGAT GGGGCTTCAACCAGGGACATCCAAACCGGAAGCACAAATCCAGGAGGCTCTCATATCCTGGAATTGCCCTCCAGGTATCCTCAGTCTTTC TGCTTTACTATTTCCTCTCCTTCCGGCTTATTTGTGGTATACTGGAAGCCCATAAAGCATTCTTGCTCATCTCCAAATAAAACGTGTTTT ATTCCTTTAGCGTGGTAAATATAGCTCTATGGCTGATTACTGTTGATAGAATATTCATTTTATGGCAAGGAAATCATCTAAACCCATAAC CATAGTTTCAATGTACATAAACCCAGGCTGAAAATATTTTTTAACTCCTCAAATACAAATAAATTAATGAACCCATGAGAAATGTCATAT >In-frame_FKBP10_ENST00000321562_chr17_39969531_+_KRT40_ENST00000398486_chr17_39138715_-_1430nt AGAGGACAGGAAGAGGGGGAGCCAGTTCTGGGAGGCGGGGGGAAGGAGGTTGGTGGCGACTCCCTCGCTCGCCCTCACTGCCGGCGGTCC CAACTCCAGGCACCATGTTCCCCGCGGGCCCCCCCAGCCACAGCCTCCTCCGGCTCCCCCTGCTGCAGTTGCTGCTACTGGTGGTGCAGG CCGTGGGGAGGGGGCTGGGCCGCGCCAGCCCGGCCGGGGGCCCCCTGGAAGATGTGGTCATCGAGAGGTACCACATCCCCAGGGCCTGTC CCCGGGAAGTGCAGATGGGGGATTTTGTGCGCTACCACTACAACGGCACTTTTGAAGATGGCAAGAAGTTTGATTCAAGGTACGAGAGTG AACTGTCCCTTCGCCAGCTGTTAGAGGCTGACATCAGCAGCCTGCATGGGATCCTGGAGGAACTGACCCTGTGCAAATCTGATCTGGAGG CCCATGTGGAGTCTCTGAAGGAAGATCTCCTTTGCCTTAAGAAAAACCATGAAGAGGAAGTCAACTTGCTTCGTGAACAGCTTGGCGACC GCCTCAGTGTGGAGCTGGACACTGCCCCCACCCTTGACCTCAACAGGGTCCTGGATGAGATGCGCTGTCAGTGTGAAACGGTGCTTGCCA ACAATCGCAGAGAAGCTGAAGAATGGTTGGCTGTTCAGACAGAAGAGCTGAATCAGCAGCAACTGTCCAGCGCGGAGCAGCTGCAGGGCT GCCAGATGGAGATCTTGGAACTGAAACGCACAGCCAGTGCTCTGGAAATTGAGCTCCAAGCACAGCAAAGCCTGACAGAATCTCTGGAAT GCACCGTGGCAGAAACCGAGGCCCAGTACAGCTCCCAGCTGGCCCAAATTCAGTGTCTGATCGATAACCTGGAGAACCAGCTGGCCGAGA TCCGCTGCGACCTGGAGCGACAGAACCAGGAGTACCAGGTGCTCCTGGACGTGAAGGCCCGGCTGGAGGGTGAGATCAACACGTACTGGG GCCTGCTGGACAGCGAGGACAGCAGGCTTTCCTGTAGCCCATGTTCGACCACATGCACCTCGAGCAACACTTGTGAGCCATGCTCAGCCT ATGTCATCTGCACTGTTGAAAACTGCTGCTTGTGAATGTTAAGGACAGCAGGTAGAGGAATCAAAGCCAGCAGCATCCTAGAAAGGAGAT GGGGCTTCAACCAGGGACATCCAAACCGGAAGCACAAATCCAGGAGGCTCTCATATCCTGGAATTGCCCTCCAGGTATCCTCAGTCTTTC TGCTTTACTATTTCCTCTCCTTCCGGCTTATTTGTGGTATACTGGAAGCCCATAAAGCATTCTTGCTCATCTCCAAATAAAACGTGTTTT |
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FusionGenePPI for FKBP10_KRT40 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FKBP10 | SLX1B, H2AFX, SLC2A4, COA7, ECE1, ACTR3, ARPC4, DDX5, EFTUD1, DNAAF5, HSPBP1, P3H1, LPP, NPLOC4, PPME1, PPP1R7, TTLL12, ZPR1, TCTN1, CHCHD2, DUSP13, TMCC2, PTPRO, TRIM25 | KRT40 | AES, ALDH3B1, FASLG, AQP1, AQP5, ZFHX3, BARD1, BYSL, CA6, CCNG1, CD33, CNTF, COL8A1, COMT, SLC25A10, CTSZ, DCX, DDX6, DOCK2, DTNB, FKBP1B, FRG1, GATA2, GEM, GNAI2, GNG5, NPBWR2, HBA2, HBZ, HCK, HOXA1, HSPD1, INPP5D, ITGB5, KIFC3, KPNA2, KRT2, KRT4, KRT5, KRT6A, KRT8, KRT81, LMO1, LMO2, LRCH4, MFAP1, MOS, MXI1, NAB2, NINJ1, NPPB, OPCML, CDK18, PIN1, PKD2, PRKAA1, PRKAB2, PSMA1, PSMC5, PTGER3, PXMP2, RAB3IL1, RAC1, RPL11, SRSF2, SMARCE1, SNAI1, SNRPB, SPG7, SSX2, TCEA2, TCEB3, TIE1, TMSB4X, TNNT1, TYK2, TYRO3, WT1, ZNF20, ZNF26, ZSCAN21, ZNF124, ZNF138, ZBTB16, ZNF165, ZNF202, ZNF230, AKAP17A, LAGE3, UXT, RECK, LMO4, ASMTL, CDK5R1, AP1M1, USP2, MTA1, HGS, DLGAP2, GTF3C5, COX5A, EIF4E2, CREB5, TRAF4, CEP57, UTP14C, HDAC4, ZBTB24, JOSD1, NR1D2, TROAP, RWDD2B, BCAS2, NXF1, KAT5, SLU7, MAB21L2, PDLIM5, FARS2, ZNF266, NEK6, ARID5A, FAM107A, BAHD1, SNW1, MAPKBP1, QPRT, ISCU, DAAM2, ZFYVE26, PGLS, TXN2, SPEF1, PRPF31, ZNF337, CHIC2, USP21, FOXB1, CYTH4, RSPH14, POLL, POM121L8P, CELA2B, CHCHD2, PHF21A, WT1-AS, POP5, ZNF581, UBASH3A, SHC3, CYCS, GFOD1, FBXW5, KRT20, FAM64A, CCDC93, CCHCR1, KCTD9, GATAD2A, SEMA4C, CHCHD3, C1orf109, FBXO34, UACA, TAPBPL, MAGOHB, FAM90A1, C19orf73, C14orf105, SETD5, RBM41, C19orf66, TRPV6, TBC1D22B, ZNF446, GPATCH2L, LIMS2, RCOR3, LIN37, FAM214A, SMCO4, ADAMTSL3, CBX8, ZNF286A, ZNF490, TSHZ3, CCDC146, RNF213, ZNF317, MARK4, ZNF250, DMRT3, AVPI1, SCOC, SH2D4A, CARD9, METTL17, AEN, TTC23, MRPL11, ZFP69B, OTUB2, C20orf195, ZNF655, ZFYVE21, LENG1, C19orf57, WDR25, TMEM231, ARMC7, C22orf46, ZNF329, ZC2HC1C, FAM124B, TNIP3, ZNF702P, FBXL18, ZFP2, THAP7, NDEL1, TXNDC5, TSC22D4, DOCK8, SLIRP, TTC25, RASSF5, GUCD1, USHBP1, PRAM1, TCHP, POLDIP3, ING5, UTP23, ZGPAT, BEX2, NFKBID, ANKRD36BP1, ZNF587, TMEM241, FBF1, CCDC120, ZNF625, ZNF439, ZNF697, LMF2, ATPAF2, NAPRT, PIGS, ZNF101, KRT71, MED8, PTPMT1, HAUS1, EXOC3-AS1, HSPA12B, RAB3IP, SSX2IP, ZNF488, TBC1D16, ZNF792, C1orf216, SNHG11, CCDC26, KRT72, SIRPA, CWF19L2, ZNF417, ZNF569, SYT6, MOB3C, DCDC2B, LOC149950, ALS2CR11, ZMAT2, CCDC112, C6orf165, IQUB, C8orf48, ZNF564, CCDC185, CDC20B, PPP1R18, FAM71C, CCER1, GGN, TXLNA, SPATA24, UCMA, ZBTB38, TTLL10, TSGA10IP, LINC01588, GOLGA6L2, ZNF844, RTP5, LINC00636, C5orf60, CEP57L1, KRT6C, TRIM42, ARSI, KLHL38, CLEC18A, LCE3E, CATIP, GLIDR, BMS1P5, C11orf87, FAM74A4, C10orf62, C6orf226, ZNRF2P1, FAM27E3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FKBP10_KRT40 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FKBP10_KRT40 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | FKBP10 | C1850168 | Bruck syndrome 1 | 1 | UNIPROT |
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