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Fusion gene ID: 13148 |
FusionGeneSummary for FBXO18_FRMD4A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FBXO18_FRMD4A | Fusion gene ID: 13148 | Hgene | Tgene | Gene symbol | FBXO18 | FRMD4A | Gene ID | 55691 |
| Gene name | FERM domain containing 4A | ||
| Synonyms | CCAFCA|FRMD4|bA295P9.4 | ||
| Cytomap | 10p13 | ||
| Type of gene | protein-coding | ||
| Description | FERM domain-containing protein 4AFERM domain containing 4 | ||
| Modification date | 20180519 | ||
| UniProtAcc | Q9P2Q2 | ||
| Ensembl transtripts involved in fusion gene | ENST00000397269, ENST00000362091, ENST00000470089, ENST00000379999, | ENST00000358621, ENST00000357447, ENST00000378503, ENST00000342409, ENST00000493380, ENST00000475141, ENST00000492155, | |
| Fusion gene scores | * DoF score | 3 X 3 X 3=27 | 9 X 7 X 6=378 |
| # samples | 3 | 10 | |
| ** MAII score | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(10/378*10)=-1.91838623444635 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FBXO18 [Title/Abstract] AND FRMD4A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-J4-A83M-01A | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000397269 | ENST00000358621 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-3CDS | ENST00000397269 | ENST00000357447 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-3CDS | ENST00000397269 | ENST00000378503 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-intron | ENST00000397269 | ENST00000342409 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-intron | ENST00000397269 | ENST00000493380 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-intron | ENST00000397269 | ENST00000475141 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-intron | ENST00000397269 | ENST00000492155 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| In-frame | ENST00000362091 | ENST00000358621 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| In-frame | ENST00000362091 | ENST00000357447 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| In-frame | ENST00000362091 | ENST00000378503 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| 5CDS-intron | ENST00000362091 | ENST00000342409 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| 5CDS-intron | ENST00000362091 | ENST00000493380 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| 5CDS-intron | ENST00000362091 | ENST00000475141 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| 5CDS-intron | ENST00000362091 | ENST00000492155 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| 3UTR-3CDS | ENST00000470089 | ENST00000358621 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| 3UTR-3CDS | ENST00000470089 | ENST00000357447 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| 3UTR-3CDS | ENST00000470089 | ENST00000378503 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| 3UTR-intron | ENST00000470089 | ENST00000342409 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| 3UTR-intron | ENST00000470089 | ENST00000493380 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| 3UTR-intron | ENST00000470089 | ENST00000475141 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| 3UTR-intron | ENST00000470089 | ENST00000492155 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-3CDS | ENST00000379999 | ENST00000358621 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-3CDS | ENST00000379999 | ENST00000357447 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-3CDS | ENST00000379999 | ENST00000378503 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-intron | ENST00000379999 | ENST00000342409 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-intron | ENST00000379999 | ENST00000493380 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-intron | ENST00000379999 | ENST00000475141 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
| intron-intron | ENST00000379999 | ENST00000492155 | FBXO18 | chr10 | 5932309 | + | FRMD4A | chr10 | 13717044 | - |
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FusionProtFeatures for FBXO18_FRMD4A |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FBXO18 | FRMD4A |
| Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. | Scaffolding protein that regulates epithelial cellpolarity by connecting ARF6 activation with the PAR3 complex (Bysimilarity). Plays a redundant role with FRMD4B in epithelialpolarization (By similarity). May regulate MAPT secretion byactivating ARF6-signaling (PubMed:27044754).{ECO:0000250|UniProtKB:Q8BIE6, ECO:0000269|PubMed:27044754}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for FBXO18_FRMD4A |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FBXO18_ENST00000362091_chr10_5932309_+_FRMD4A_ENST00000358621_chr10_13717044_-_668aa SSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAEL ERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLE DEDSQVTSTISPLHSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTG SCAEAGGGSNSLQNSPIRGLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYT PRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARGGAGGAGGAGGGVYL HSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGGDEGDTGRLTPSRSQILRTPSLGRE GAHDKGAGRAAVSDELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGA >In-frame_FBXO18_ENST00000362091_chr10_5932309_+_FRMD4A_ENST00000357447_chr10_13717044_-_668aa SSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAEL ERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLE DEDSQVTSTISPLHSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTG SCAEAGGGSNSLQNSPIRGLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYT PRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARGGAGGAGGAGGGVYL HSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGGDEGDTGRLTPSRSQILRTPSLGRE GAHDKGAGRAAVSDELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGA >In-frame_FBXO18_ENST00000362091_chr10_5932309_+_FRMD4A_ENST00000378503_chr10_13717044_-_668aa SSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKLCLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAEL ERLEREFAIQSQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLIIDDGNIASEDSSLSDALVLE DEDSQVTSTISPLHSPHKGLPPRPPSHNRPPPPQSLEGLRQMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSSHSHSSSHKRFPSTG SCAEAGGGSNSLQNSPIRGLPHWNSQSSMPSTPDLRVRSPHYVHSTRSVDISPTRLHSLALHFRHRSSSLESQGKLLGSENDTGSPDFYT PRTRSSNGSDPMDDCSSCTSHSSSEHYYPAQMNANYSTLAEDSPSKARQRQRQRQRAAGALGSASSGSMPNLAARGGAGGAGGAGGGVYL HSQSQPSSQYRIKEYPLYIEGGATPVVVRSLESDQEGHYSVKAQFKTSNSYTAGGLFKESWRGGGGDEGDTGRLTPSRSQILRTPSLGRE GAHDKGAGRAAVSDELRQWYQRSTASHKEHSRLSHTSSTSSDSGSQYSTSSQSTFVAHSRVTRMPQMCKATSAALPQSQRSSTPSSEIGA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FBXO18_ENST00000362091_chr10_5932309_+_FRMD4A_ENST00000358621_chr10_13717044_-_2004nt AGTTCTCAGGAATCAGATAGCTCGCAGTCGGCCAAGAAGGACATGCTGGCTGCCTTGAAGTCCAGGCAGGAAGCTCTGGAGGAAACCCTG CGTCAGAGGCTGGAGGAACTGAAGAAGCTGTGTCTCCGAGAAGCTGAGCTCACGGGCAAGCTGCCAGTAGAATATCCCCTGGATCCAGGG GAGGAACCACCCATTGTTCGGAGAAGAATAGGAACAGCCTTCAAACTGGATGAACAGAAAATCCTGCCCAAAGGAGAGGAAGCTGAGCTG GAACGCCTGGAACGAGAGTTTGCCATTCAGTCCCAGATTACGGAGGCCGCCCGCCGCCTAGCCAGTGACCCCAACGTCAGCAAAAAACTG AAGAAACAAAGGAAAACCTCGTATCTGAATGCACTGAAGAAACTGCAGGAGATTGAAAATGCAATCAATGAGAACCGCATCAAGTCTGGG AAGAAACCCACCCAGAGGGCTTCGCTGATCATAGACGATGGAAACATTGCCAGTGAAGACAGCTCCCTCTCAGATGCCCTTGTTCTTGAG GATGAAGACTCTCAGGTTACCAGCACAATATCCCCCCTACATTCTCCTCACAAGGGACTCCCTCCTCGGCCACCGTCGCACAACAGGCCT CCTCCTCCCCAGTCCCTGGAGGGACTCCGACAGATGCACTATCACCGCAACGACTATGACAAGTCACCCATCAAGCCCAAAATGTGGAGT GAGTCCTCTTTAGATGAACCCTATGAGAAGGTCAAGAAGCGCTCCTCTCACAGCCATTCCAGCAGCCACAAGCGCTTCCCCAGCACAGGA AGCTGTGCGGAAGCCGGCGGAGGAAGCAACTCCTTGCAGAACAGCCCCATCCGCGGCCTCCCGCACTGGAACTCCCAGTCCAGCATGCCG TCCACGCCAGACCTGCGGGTCCGGAGTCCCCACTACGTCCATTCCACGAGGTCGGTGGACATCAGCCCCACCCGACTGCACAGCCTCGCA CTGCACTTTAGGCACCGGAGCTCCAGCCTGGAGTCCCAGGGCAAGCTCCTGGGCTCGGAAAACGACACCGGGAGCCCCGACTTCTACACC CCGCGGACTCGTAGCAGCAACGGCTCAGACCCCATGGACGACTGCTCGTCGTGCACCAGCCACTCGAGCTCGGAGCACTACTACCCGGCG CAGATGAACGCCAACTACTCCACGCTGGCCGAGGACTCGCCGTCCAAGGCGCGCCAGAGGCAGAGGCAGCGGCAGCGGGCGGCGGGCGCA CTGGGCTCAGCCAGCTCGGGCAGCATGCCCAACCTGGCGGCGCGCGGGGGTGCGGGGGGCGCGGGGGGCGCGGGGGGCGGTGTGTACCTG CACAGCCAGAGCCAGCCCAGCTCGCAGTACCGCATCAAGGAGTACCCGCTGTACATCGAGGGCGGCGCCACGCCCGTGGTGGTGCGCAGC CTGGAGAGCGACCAGGAGGGCCACTACAGCGTCAAGGCTCAGTTCAAGACGTCCAACTCCTACACGGCGGGCGGCCTGTTCAAGGAGAGC TGGCGCGGCGGCGGCGGCGACGAGGGCGACACGGGCCGCCTGACGCCGTCGCGATCGCAGATCCTGCGGACTCCGTCGCTGGGCCGCGAG GGCGCCCACGACAAGGGCGCGGGCCGTGCCGCCGTCTCAGACGAGCTGCGCCAGTGGTACCAGCGTTCCACCGCCTCGCACAAGGAGCAC AGCCGCCTGTCGCACACCAGCTCCACCTCCTCGGACAGCGGCTCGCAGTACAGCACCTCCTCCCAGAGCACCTTCGTGGCGCACAGCAGG GTCACCAGGATGCCCCAGATGTGCAAGGCCACGTCAGCTGCCTTACCTCAAAGCCAGAGAAGCTCGACACCGTCAAGTGAAATTGGAGCC ACCCCCCCAAGCAGCCCCCACCACATCCTAACCTGGCAGACTGGAGAAGCAACAGAAAACTCACCCATTCTGGATGGGTCTGAGTCTCCA >In-frame_FBXO18_ENST00000362091_chr10_5932309_+_FRMD4A_ENST00000357447_chr10_13717044_-_2004nt AGTTCTCAGGAATCAGATAGCTCGCAGTCGGCCAAGAAGGACATGCTGGCTGCCTTGAAGTCCAGGCAGGAAGCTCTGGAGGAAACCCTG CGTCAGAGGCTGGAGGAACTGAAGAAGCTGTGTCTCCGAGAAGCTGAGCTCACGGGCAAGCTGCCAGTAGAATATCCCCTGGATCCAGGG GAGGAACCACCCATTGTTCGGAGAAGAATAGGAACAGCCTTCAAACTGGATGAACAGAAAATCCTGCCCAAAGGAGAGGAAGCTGAGCTG GAACGCCTGGAACGAGAGTTTGCCATTCAGTCCCAGATTACGGAGGCCGCCCGCCGCCTAGCCAGTGACCCCAACGTCAGCAAAAAACTG AAGAAACAAAGGAAAACCTCGTATCTGAATGCACTGAAGAAACTGCAGGAGATTGAAAATGCAATCAATGAGAACCGCATCAAGTCTGGG AAGAAACCCACCCAGAGGGCTTCGCTGATCATAGACGATGGAAACATTGCCAGTGAAGACAGCTCCCTCTCAGATGCCCTTGTTCTTGAG GATGAAGACTCTCAGGTTACCAGCACAATATCCCCCCTACATTCTCCTCACAAGGGACTCCCTCCTCGGCCACCGTCGCACAACAGGCCT CCTCCTCCCCAGTCCCTGGAGGGACTCCGACAGATGCACTATCACCGCAACGACTATGACAAGTCACCCATCAAGCCCAAAATGTGGAGT GAGTCCTCTTTAGATGAACCCTATGAGAAGGTCAAGAAGCGCTCCTCTCACAGCCATTCCAGCAGCCACAAGCGCTTCCCCAGCACAGGA AGCTGTGCGGAAGCCGGCGGAGGAAGCAACTCCTTGCAGAACAGCCCCATCCGCGGCCTCCCGCACTGGAACTCCCAGTCCAGCATGCCG TCCACGCCAGACCTGCGGGTCCGGAGTCCCCACTACGTCCATTCCACGAGGTCGGTGGACATCAGCCCCACCCGACTGCACAGCCTCGCA CTGCACTTTAGGCACCGGAGCTCCAGCCTGGAGTCCCAGGGCAAGCTCCTGGGCTCGGAAAACGACACCGGGAGCCCCGACTTCTACACC CCGCGGACTCGTAGCAGCAACGGCTCAGACCCCATGGACGACTGCTCGTCGTGCACCAGCCACTCGAGCTCGGAGCACTACTACCCGGCG CAGATGAACGCCAACTACTCCACGCTGGCCGAGGACTCGCCGTCCAAGGCGCGCCAGAGGCAGAGGCAGCGGCAGCGGGCGGCGGGCGCA CTGGGCTCAGCCAGCTCGGGCAGCATGCCCAACCTGGCGGCGCGCGGGGGTGCGGGGGGCGCGGGGGGCGCGGGGGGCGGTGTGTACCTG CACAGCCAGAGCCAGCCCAGCTCGCAGTACCGCATCAAGGAGTACCCGCTGTACATCGAGGGCGGCGCCACGCCCGTGGTGGTGCGCAGC CTGGAGAGCGACCAGGAGGGCCACTACAGCGTCAAGGCTCAGTTCAAGACGTCCAACTCCTACACGGCGGGCGGCCTGTTCAAGGAGAGC TGGCGCGGCGGCGGCGGCGACGAGGGCGACACGGGCCGCCTGACGCCGTCGCGATCGCAGATCCTGCGGACTCCGTCGCTGGGCCGCGAG GGCGCCCACGACAAGGGCGCGGGCCGTGCCGCCGTCTCAGACGAGCTGCGCCAGTGGTACCAGCGTTCCACCGCCTCGCACAAGGAGCAC AGCCGCCTGTCGCACACCAGCTCCACCTCCTCGGACAGCGGCTCGCAGTACAGCACCTCCTCCCAGAGCACCTTCGTGGCGCACAGCAGG GTCACCAGGATGCCCCAGATGTGCAAGGCCACGTCAGCTGCCTTACCTCAAAGCCAGAGAAGCTCGACACCGTCAAGTGAAATTGGAGCC ACCCCCCCAAGCAGCCCCCACCACATCCTAACCTGGCAGACTGGAGAAGCAACAGAAAACTCACCCATTCTGGATGGGTCTGAGTCTCCA >In-frame_FBXO18_ENST00000362091_chr10_5932309_+_FRMD4A_ENST00000378503_chr10_13717044_-_2004nt AGTTCTCAGGAATCAGATAGCTCGCAGTCGGCCAAGAAGGACATGCTGGCTGCCTTGAAGTCCAGGCAGGAAGCTCTGGAGGAAACCCTG CGTCAGAGGCTGGAGGAACTGAAGAAGCTGTGTCTCCGAGAAGCTGAGCTCACGGGCAAGCTGCCAGTAGAATATCCCCTGGATCCAGGG GAGGAACCACCCATTGTTCGGAGAAGAATAGGAACAGCCTTCAAACTGGATGAACAGAAAATCCTGCCCAAAGGAGAGGAAGCTGAGCTG GAACGCCTGGAACGAGAGTTTGCCATTCAGTCCCAGATTACGGAGGCCGCCCGCCGCCTAGCCAGTGACCCCAACGTCAGCAAAAAACTG AAGAAACAAAGGAAAACCTCGTATCTGAATGCACTGAAGAAACTGCAGGAGATTGAAAATGCAATCAATGAGAACCGCATCAAGTCTGGG AAGAAACCCACCCAGAGGGCTTCGCTGATCATAGACGATGGAAACATTGCCAGTGAAGACAGCTCCCTCTCAGATGCCCTTGTTCTTGAG GATGAAGACTCTCAGGTTACCAGCACAATATCCCCCCTACATTCTCCTCACAAGGGACTCCCTCCTCGGCCACCGTCGCACAACAGGCCT CCTCCTCCCCAGTCCCTGGAGGGACTCCGACAGATGCACTATCACCGCAACGACTATGACAAGTCACCCATCAAGCCCAAAATGTGGAGT GAGTCCTCTTTAGATGAACCCTATGAGAAGGTCAAGAAGCGCTCCTCTCACAGCCATTCCAGCAGCCACAAGCGCTTCCCCAGCACAGGA AGCTGTGCGGAAGCCGGCGGAGGAAGCAACTCCTTGCAGAACAGCCCCATCCGCGGCCTCCCGCACTGGAACTCCCAGTCCAGCATGCCG TCCACGCCAGACCTGCGGGTCCGGAGTCCCCACTACGTCCATTCCACGAGGTCGGTGGACATCAGCCCCACCCGACTGCACAGCCTCGCA CTGCACTTTAGGCACCGGAGCTCCAGCCTGGAGTCCCAGGGCAAGCTCCTGGGCTCGGAAAACGACACCGGGAGCCCCGACTTCTACACC CCGCGGACTCGTAGCAGCAACGGCTCAGACCCCATGGACGACTGCTCGTCGTGCACCAGCCACTCGAGCTCGGAGCACTACTACCCGGCG CAGATGAACGCCAACTACTCCACGCTGGCCGAGGACTCGCCGTCCAAGGCGCGCCAGAGGCAGAGGCAGCGGCAGCGGGCGGCGGGCGCA CTGGGCTCAGCCAGCTCGGGCAGCATGCCCAACCTGGCGGCGCGCGGGGGTGCGGGGGGCGCGGGGGGCGCGGGGGGCGGTGTGTACCTG CACAGCCAGAGCCAGCCCAGCTCGCAGTACCGCATCAAGGAGTACCCGCTGTACATCGAGGGCGGCGCCACGCCCGTGGTGGTGCGCAGC CTGGAGAGCGACCAGGAGGGCCACTACAGCGTCAAGGCTCAGTTCAAGACGTCCAACTCCTACACGGCGGGCGGCCTGTTCAAGGAGAGC TGGCGCGGCGGCGGCGGCGACGAGGGCGACACGGGCCGCCTGACGCCGTCGCGATCGCAGATCCTGCGGACTCCGTCGCTGGGCCGCGAG GGCGCCCACGACAAGGGCGCGGGCCGTGCCGCCGTCTCAGACGAGCTGCGCCAGTGGTACCAGCGTTCCACCGCCTCGCACAAGGAGCAC AGCCGCCTGTCGCACACCAGCTCCACCTCCTCGGACAGCGGCTCGCAGTACAGCACCTCCTCCCAGAGCACCTTCGTGGCGCACAGCAGG GTCACCAGGATGCCCCAGATGTGCAAGGCCACGTCAGCTGCCTTACCTCAAAGCCAGAGAAGCTCGACACCGTCAAGTGAAATTGGAGCC ACCCCCCCAAGCAGCCCCCACCACATCCTAACCTGGCAGACTGGAGAAGCAACAGAAAACTCACCCATTCTGGATGGGTCTGAGTCTCCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FBXO18_ENST00000362091_chr10_5932309_+_FRMD4A_ENST00000358621_chr10_13717044_-_5451nt CTCGGGCTCCAGGTCCCGGCCAGAGGAGGAGCTCGCTGCCGGGGGACGCTGGGCTGAGCGGCCGGCGGCGCGGGCCCGGCGGCGGCGGCA GCGGGGTCCGGGTCCGGAGCGCCACAGTTCTCAGGAATCAGATAGCTCGCAGTCGGCCAAGAAGGACATGCTGGCTGCCTTGAAGTCCAG GCAGGAAGCTCTGGAGGAAACCCTGCGTCAGAGGCTGGAGGAACTGAAGAAGCTGTGTCTCCGAGAAGCTGAGCTCACGGGCAAGCTGCC AGTAGAATATCCCCTGGATCCAGGGGAGGAACCACCCATTGTTCGGAGAAGAATAGGAACAGCCTTCAAACTGGATGAACAGAAAATCCT GCCCAAAGGAGAGGAAGCTGAGCTGGAACGCCTGGAACGAGAGTTTGCCATTCAGTCCCAGATTACGGAGGCCGCCCGCCGCCTAGCCAG TGACCCCAACGTCAGCAAAAAACTGAAGAAACAAAGGAAAACCTCGTATCTGAATGCACTGAAGAAACTGCAGGAGATTGAAAATGCAAT CAATGAGAACCGCATCAAGTCTGGGAAGAAACCCACCCAGAGGGCTTCGCTGATCATAGACGATGGAAACATTGCCAGTGAAGACAGCTC CCTCTCAGATGCCCTTGTTCTTGAGGATGAAGACTCTCAGGTTACCAGCACAATATCCCCCCTACATTCTCCTCACAAGGGACTCCCTCC TCGGCCACCGTCGCACAACAGGCCTCCTCCTCCCCAGTCCCTGGAGGGACTCCGACAGATGCACTATCACCGCAACGACTATGACAAGTC ACCCATCAAGCCCAAAATGTGGAGTGAGTCCTCTTTAGATGAACCCTATGAGAAGGTCAAGAAGCGCTCCTCTCACAGCCATTCCAGCAG CCACAAGCGCTTCCCCAGCACAGGAAGCTGTGCGGAAGCCGGCGGAGGAAGCAACTCCTTGCAGAACAGCCCCATCCGCGGCCTCCCGCA CTGGAACTCCCAGTCCAGCATGCCGTCCACGCCAGACCTGCGGGTCCGGAGTCCCCACTACGTCCATTCCACGAGGTCGGTGGACATCAG CCCCACCCGACTGCACAGCCTCGCACTGCACTTTAGGCACCGGAGCTCCAGCCTGGAGTCCCAGGGCAAGCTCCTGGGCTCGGAAAACGA CACCGGGAGCCCCGACTTCTACACCCCGCGGACTCGTAGCAGCAACGGCTCAGACCCCATGGACGACTGCTCGTCGTGCACCAGCCACTC GAGCTCGGAGCACTACTACCCGGCGCAGATGAACGCCAACTACTCCACGCTGGCCGAGGACTCGCCGTCCAAGGCGCGCCAGAGGCAGAG GCAGCGGCAGCGGGCGGCGGGCGCACTGGGCTCAGCCAGCTCGGGCAGCATGCCCAACCTGGCGGCGCGCGGGGGTGCGGGGGGCGCGGG GGGCGCGGGGGGCGGTGTGTACCTGCACAGCCAGAGCCAGCCCAGCTCGCAGTACCGCATCAAGGAGTACCCGCTGTACATCGAGGGCGG CGCCACGCCCGTGGTGGTGCGCAGCCTGGAGAGCGACCAGGAGGGCCACTACAGCGTCAAGGCTCAGTTCAAGACGTCCAACTCCTACAC GGCGGGCGGCCTGTTCAAGGAGAGCTGGCGCGGCGGCGGCGGCGACGAGGGCGACACGGGCCGCCTGACGCCGTCGCGATCGCAGATCCT GCGGACTCCGTCGCTGGGCCGCGAGGGCGCCCACGACAAGGGCGCGGGCCGTGCCGCCGTCTCAGACGAGCTGCGCCAGTGGTACCAGCG TTCCACCGCCTCGCACAAGGAGCACAGCCGCCTGTCGCACACCAGCTCCACCTCCTCGGACAGCGGCTCGCAGTACAGCACCTCCTCCCA GAGCACCTTCGTGGCGCACAGCAGGGTCACCAGGATGCCCCAGATGTGCAAGGCCACGTCAGCTGCCTTACCTCAAAGCCAGAGAAGCTC GACACCGTCAAGTGAAATTGGAGCCACCCCCCCAAGCAGCCCCCACCACATCCTAACCTGGCAGACTGGAGAAGCAACAGAAAACTCACC CATTCTGGATGGGTCTGAGTCTCCACCTCACCAAAGTACTGATGAATAGAGGAGCTACAATGATAGCTGTTTCCTGGATTCCTCCCTCTA TCCAGAACTAGCTGATGTCCAGTGGTACGGGCAGGAAAAAGCCAAGCCCGGGACCCTCGTGTGAGCCAGCCCGGCCTAATCTGACCGCCT CAACGCCATTCTGAGATCACCTCACTGCCTCTCATTTGCCTTACCCAGACGCACCGTCACCCTGCACCAGCTTTGGCCCTCAGCACTTTT TTTCTCCTGTCTCCGCATTCCCTCCCCCTTGAAAACCTGACTGAGGAGACATTCTGGAAGGTTCCGGTCCCACTGTGTGTCCCCTGGCGC TCTTGCCCATAGAGAGCCAGACACCAATCCTCAATGGCACCTTGGTGGCTTCCCTCTGCCATGACAGCCCCTAGGCCAGGAACCATCAGG GGGGCCAGCCGGCATCCAATTCCTGCGGATAAGTAGCGTTGGGAGAGAACGGGAAAGGGGACTTGAGTTACAGGGTGACCCAGAAAGACG ATTCAGCTGTGTCCAGCCTGCCACCCATACGTAGGCCAACCAAGCACTTCATGAAGAGGAGGCCTCGTGGCATATTCAGTTTACACCTGA AATATTCCTTGATGGGACAGCTTGTGGGGATGGCTATGGGGGAAGGGGAGGTTGAGAAAGGAAGTTCTCGACACCAGAAATGCATCGGAG GACCACAATCAGTTCTATGCTGCCAAAGATTAAAAATAAATAAAAACATAAAAAATTAAGAGGGGCCAAGAGGAAGACATTCTTTCTGCA AGGAAATTTCTTTTAAATTCTGAACTGCTACTACACACAAGTGAAAGTCAACCCTATGTAAACTGGTGTCCTCTCTCTAGCCCTCTCCCT TACTGGCCCACTTCTCTCTCCGTAGAGAGCCTGAAAAACTGCCCCAATGCCACGGTAAAGGCGAGGAAGTCTTGGCTGGCGTTGCTGACT CACAGTCGCCATCCATCTGGACACAAAGAGAGACCTGTGGGAGTCGTAGAGGGTACTGTTAGCCCCGGTCCATGCAGGGGGTTCAGCCGA GCCCAAGACTCAAAGCTGCTTTCCTTTCAGGATTTGTAGTAACGTAAGGTGATAATGGCCAAAAGTGGTTCTCTCTCATTAAACCAACCA GTAAAAGCGTATCCTATTTTTTTGCACAAGGTGTTTCATTTTCGTTTTTATGGGAAACCAAGGGAAAAGCACATTGCGATCCATTCAGTG TTTAACTGTCGTGGCTCATTTTCTGTTCGTTAGCACTTGTGTGACAAAAGAGCTCAGATCCGACTTCTCCTATGTGTCACTTATTCCAAG AACCCAACTATGCCCTTAGGTAGAAAGATTTGACTCGTGTGTCTACTAGCCAACAGGCAGAGCAGGGTTGAAAAAAATATCAGCTCCCAA AGGGCCCATGTGTCTACATCATCAGTTACTGTCATGCACCACATTTGTGTGCAGATACCAAAAGAGGAGGAAAGAAGAAAAAAATTAATG TGTGGGAGCTGCACGTTTACATGTTTTGAGCTATGCTTCAAACACAACTGGAAAGCCATCAATCTTCAAAGGCCTCAAAAATACTTTTAT AGTAACAAGTGCACGACTTTAGTTGGGTTATTCAAGATGGCACAAAAAGGTTTCCGCAGAGGTGGTATGCTGTGCTTTTGGCGCAAGTGG TGGGGGGATGGGGTGGGGGTGGAATTTTTTTCTCACTCTAATGACTTCCTATTGGAAAGGCATTGACAGCCAGGGACAGGAGCCAGGGTG GGGGTAGTTTTGTGGGAAAGCAGAACTGAAGTTAGCTTAAGCATAAAAACAAAGAAAAATCTTCGCTTTTCATGTATGTGGAATCCAAGA ATAACCATAGGCTCTACCAGACCAGAAGGGTAAGGATGGACACTAAAATGAAACAAATACCAAGGTATTCCTTCTGCTGCAGCCTGGAGA CCACCGAGAGTCGAGCTGGGGCACACACACACCTGGCCGGGACCCGGCAGGGACAAGGCGGGCCGTGGCCTCCTCCACCAAGTCTCTCTA GACAATTCAGGGCCTGCTTTCCCCAGCTCCATGCATGGCTGGACTGGTGATTCCAGGGTGCAGAAGGGATTCATATTCCCAGAACGCTTT AAGTGTACACCTGCAGGATAAAGAGATACCGGTTACATTATTAAATGATTCTAGGGATTCACTGGGGGATATTTTTGTTGCTTTTACTTT CATGGTTAGAGCTACAAAGAACAGTGATTTTTTTTTTTTCTCCCTTCCCCATTCAGAAACATTATACATTGGGCCATTTTTCTTTCTCCC AAAGAAGATTCATGGATAGTCAGACTGAACTGTGTGCAACAGGAAAAGTCAAAAGGGAAAAGGTAGCTGATGAGGTTACATGGTTACATG TTCTACATCATGCATAGTAGCTTGAAATCTAGTCTGGAGAAAACTGGATCAAGATTCTAGCCCACTGGAGTTGCAAGGAATGAGAGGCAA AAATTCTAAAGATTTGGGTTATATTTTCAACTTGGGGGACAGAGAGAAATGGAGAGCAGGAATTACAGTTCCAACAAACATCATGATAGT CTGGTAGTCAAGACAGAGATTAAGTAAAACAGGTTTTACTGTTTAGCTGAGTTCAGTTAATACAAAATGTACATAAAACGTTAGTCCTTT GAGACTGACATGATTAATGATCAGTGTGGTGGGAAATGATGTAGTTATTGTACACAAGCACTTGCAAACTCTTTATCCCTATTTCTTTAA AACAAAATAAGGTGAAATACGAAGTCCTTGGTCTGATATAAAGCCCCTATTGGATTCTTCGGATGCGTAAAAGAAATTGCCTGTTTCAGC CAGAAGACTGGTGAAAACACATACATCAGACTATGTTGTGAGCCAGGTTGATTTTTTATTTTATTATATGCAGGTGAGTGTTGAAACTGT TAAAATTCCAATTTGTTTTCATTCAGTATTAGTTTAGTTCTAAATATAGCAAACCCCATCCAGGTGCTATCAGATGACCAGTTACTGCTT AGTTAACTAGGTGTAAAGTTTTACATATACATTAATGTCAATAGTTTATTACAAGTTGTGTAAAATGGACTCTAGTTTAATAATGGGGGA AAAAAGATTAGGTTGCTCCTGAAACTGACTGTAGAGCATGTAAAATGATTTTACTGGATTCTGTTCAACTGTAATCAATGAAAAAGATGT ACGTTGTAGACAAAGTTGCAGAATTAAAAAAAGAAATCTGCTTTTAATTTATTCTTTTTGTATTAAGAATTTGTATAGTACCTTTACATT >In-frame_FBXO18_ENST00000362091_chr10_5932309_+_FRMD4A_ENST00000357447_chr10_13717044_-_5445nt CTCGGGCTCCAGGTCCCGGCCAGAGGAGGAGCTCGCTGCCGGGGGACGCTGGGCTGAGCGGCCGGCGGCGCGGGCCCGGCGGCGGCGGCA GCGGGGTCCGGGTCCGGAGCGCCACAGTTCTCAGGAATCAGATAGCTCGCAGTCGGCCAAGAAGGACATGCTGGCTGCCTTGAAGTCCAG GCAGGAAGCTCTGGAGGAAACCCTGCGTCAGAGGCTGGAGGAACTGAAGAAGCTGTGTCTCCGAGAAGCTGAGCTCACGGGCAAGCTGCC AGTAGAATATCCCCTGGATCCAGGGGAGGAACCACCCATTGTTCGGAGAAGAATAGGAACAGCCTTCAAACTGGATGAACAGAAAATCCT GCCCAAAGGAGAGGAAGCTGAGCTGGAACGCCTGGAACGAGAGTTTGCCATTCAGTCCCAGATTACGGAGGCCGCCCGCCGCCTAGCCAG TGACCCCAACGTCAGCAAAAAACTGAAGAAACAAAGGAAAACCTCGTATCTGAATGCACTGAAGAAACTGCAGGAGATTGAAAATGCAAT CAATGAGAACCGCATCAAGTCTGGGAAGAAACCCACCCAGAGGGCTTCGCTGATCATAGACGATGGAAACATTGCCAGTGAAGACAGCTC CCTCTCAGATGCCCTTGTTCTTGAGGATGAAGACTCTCAGGTTACCAGCACAATATCCCCCCTACATTCTCCTCACAAGGGACTCCCTCC TCGGCCACCGTCGCACAACAGGCCTCCTCCTCCCCAGTCCCTGGAGGGACTCCGACAGATGCACTATCACCGCAACGACTATGACAAGTC ACCCATCAAGCCCAAAATGTGGAGTGAGTCCTCTTTAGATGAACCCTATGAGAAGGTCAAGAAGCGCTCCTCTCACAGCCATTCCAGCAG CCACAAGCGCTTCCCCAGCACAGGAAGCTGTGCGGAAGCCGGCGGAGGAAGCAACTCCTTGCAGAACAGCCCCATCCGCGGCCTCCCGCA CTGGAACTCCCAGTCCAGCATGCCGTCCACGCCAGACCTGCGGGTCCGGAGTCCCCACTACGTCCATTCCACGAGGTCGGTGGACATCAG CCCCACCCGACTGCACAGCCTCGCACTGCACTTTAGGCACCGGAGCTCCAGCCTGGAGTCCCAGGGCAAGCTCCTGGGCTCGGAAAACGA CACCGGGAGCCCCGACTTCTACACCCCGCGGACTCGTAGCAGCAACGGCTCAGACCCCATGGACGACTGCTCGTCGTGCACCAGCCACTC GAGCTCGGAGCACTACTACCCGGCGCAGATGAACGCCAACTACTCCACGCTGGCCGAGGACTCGCCGTCCAAGGCGCGCCAGAGGCAGAG GCAGCGGCAGCGGGCGGCGGGCGCACTGGGCTCAGCCAGCTCGGGCAGCATGCCCAACCTGGCGGCGCGCGGGGGTGCGGGGGGCGCGGG GGGCGCGGGGGGCGGTGTGTACCTGCACAGCCAGAGCCAGCCCAGCTCGCAGTACCGCATCAAGGAGTACCCGCTGTACATCGAGGGCGG CGCCACGCCCGTGGTGGTGCGCAGCCTGGAGAGCGACCAGGAGGGCCACTACAGCGTCAAGGCTCAGTTCAAGACGTCCAACTCCTACAC GGCGGGCGGCCTGTTCAAGGAGAGCTGGCGCGGCGGCGGCGGCGACGAGGGCGACACGGGCCGCCTGACGCCGTCGCGATCGCAGATCCT GCGGACTCCGTCGCTGGGCCGCGAGGGCGCCCACGACAAGGGCGCGGGCCGTGCCGCCGTCTCAGACGAGCTGCGCCAGTGGTACCAGCG TTCCACCGCCTCGCACAAGGAGCACAGCCGCCTGTCGCACACCAGCTCCACCTCCTCGGACAGCGGCTCGCAGTACAGCACCTCCTCCCA GAGCACCTTCGTGGCGCACAGCAGGGTCACCAGGATGCCCCAGATGTGCAAGGCCACGTCAGCTGCCTTACCTCAAAGCCAGAGAAGCTC GACACCGTCAAGTGAAATTGGAGCCACCCCCCCAAGCAGCCCCCACCACATCCTAACCTGGCAGACTGGAGAAGCAACAGAAAACTCACC CATTCTGGATGGGTCTGAGTCTCCACCTCACCAAAGTACTGATGAATAGAGGAGCTACAATGATAGCTGTTTCCTGGATTCCTCCCTCTA TCCAGAACTAGCTGATGTCCAGTGGTACGGGCAGGAAAAAGCCAAGCCCGGGACCCTCGTGTGAGCCAGCCCGGCCTAATCTGACCGCCT CAACGCCATTCTGAGATCACCTCACTGCCTCTCATTTGCCTTACCCAGACGCACCGTCACCCTGCACCAGCTTTGGCCCTCAGCACTTTT TTTCTCCTGTCTCCGCATTCCCTCCCCCTTGAAAACCTGACTGAGGAGACATTCTGGAAGGTTCCGGTCCCACTGTGTGTCCCCTGGCGC TCTTGCCCATAGAGAGCCAGACACCAATCCTCAATGGCACCTTGGTGGCTTCCCTCTGCCATGACAGCCCCTAGGCCAGGAACCATCAGG GGGGCCAGCCGGCATCCAATTCCTGCGGATAAGTAGCGTTGGGAGAGAACGGGAAAGGGGACTTGAGTTACAGGGTGACCCAGAAAGACG ATTCAGCTGTGTCCAGCCTGCCACCCATACGTAGGCCAACCAAGCACTTCATGAAGAGGAGGCCTCGTGGCATATTCAGTTTACACCTGA AATATTCCTTGATGGGACAGCTTGTGGGGATGGCTATGGGGGAAGGGGAGGTTGAGAAAGGAAGTTCTCGACACCAGAAATGCATCGGAG GACCACAATCAGTTCTATGCTGCCAAAGATTAAAAATAAATAAAAACATAAAAAATTAAGAGGGGCCAAGAGGAAGACATTCTTTCTGCA AGGAAATTTCTTTTAAATTCTGAACTGCTACTACACACAAGTGAAAGTCAACCCTATGTAAACTGGTGTCCTCTCTCTAGCCCTCTCCCT TACTGGCCCACTTCTCTCTCCGTAGAGAGCCTGAAAAACTGCCCCAATGCCACGGTAAAGGCGAGGAAGTCTTGGCTGGCGTTGCTGACT CACAGTCGCCATCCATCTGGACACAAAGAGAGACCTGTGGGAGTCGTAGAGGGTACTGTTAGCCCCGGTCCATGCAGGGGGTTCAGCCGA GCCCAAGACTCAAAGCTGCTTTCCTTTCAGGATTTGTAGTAACGTAAGGTGATAATGGCCAAAAGTGGTTCTCTCTCATTAAACCAACCA GTAAAAGCGTATCCTATTTTTTTGCACAAGGTGTTTCATTTTCGTTTTTATGGGAAACCAAGGGAAAAGCACATTGCGATCCATTCAGTG TTTAACTGTCGTGGCTCATTTTCTGTTCGTTAGCACTTGTGTGACAAAAGAGCTCAGATCCGACTTCTCCTATGTGTCACTTATTCCAAG AACCCAACTATGCCCTTAGGTAGAAAGATTTGACTCGTGTGTCTACTAGCCAACAGGCAGAGCAGGGTTGAAAAAAATATCAGCTCCCAA AGGGCCCATGTGTCTACATCATCAGTTACTGTCATGCACCACATTTGTGTGCAGATACCAAAAGAGGAGGAAAGAAGAAAAAAATTAATG TGTGGGAGCTGCACGTTTACATGTTTTGAGCTATGCTTCAAACACAACTGGAAAGCCATCAATCTTCAAAGGCCTCAAAAATACTTTTAT AGTAACAAGTGCACGACTTTAGTTGGGTTATTCAAGATGGCACAAAAAGGTTTCCGCAGAGGTGGTATGCTGTGCTTTTGGCGCAAGTGG TGGGGGGATGGGGTGGGGGTGGAATTTTTTTCTCACTCTAATGACTTCCTATTGGAAAGGCATTGACAGCCAGGGACAGGAGCCAGGGTG GGGGTAGTTTTGTGGGAAAGCAGAACTGAAGTTAGCTTAAGCATAAAAACAAAGAAAAATCTTCGCTTTTCATGTATGTGGAATCCAAGA ATAACCATAGGCTCTACCAGACCAGAAGGGTAAGGATGGACACTAAAATGAAACAAATACCAAGGTATTCCTTCTGCTGCAGCCTGGAGA CCACCGAGAGTCGAGCTGGGGCACACACACACCTGGCCGGGACCCGGCAGGGACAAGGCGGGCCGTGGCCTCCTCCACCAAGTCTCTCTA GACAATTCAGGGCCTGCTTTCCCCAGCTCCATGCATGGCTGGACTGGTGATTCCAGGGTGCAGAAGGGATTCATATTCCCAGAACGCTTT AAGTGTACACCTGCAGGATAAAGAGATACCGGTTACATTATTAAATGATTCTAGGGATTCACTGGGGGATATTTTTGTTGCTTTTACTTT CATGGTTAGAGCTACAAAGAACAGTGATTTTTTTTTTTTCTCCCTTCCCCATTCAGAAACATTATACATTGGGCCATTTTTCTTTCTCCC AAAGAAGATTCATGGATAGTCAGACTGAACTGTGTGCAACAGGAAAAGTCAAAAGGGAAAAGGTAGCTGATGAGGTTACATGGTTACATG TTCTACATCATGCATAGTAGCTTGAAATCTAGTCTGGAGAAAACTGGATCAAGATTCTAGCCCACTGGAGTTGCAAGGAATGAGAGGCAA AAATTCTAAAGATTTGGGTTATATTTTCAACTTGGGGGACAGAGAGAAATGGAGAGCAGGAATTACAGTTCCAACAAACATCATGATAGT CTGGTAGTCAAGACAGAGATTAAGTAAAACAGGTTTTACTGTTTAGCTGAGTTCAGTTAATACAAAATGTACATAAAACGTTAGTCCTTT GAGACTGACATGATTAATGATCAGTGTGGTGGGAAATGATGTAGTTATTGTACACAAGCACTTGCAAACTCTTTATCCCTATTTCTTTAA AACAAAATAAGGTGAAATACGAAGTCCTTGGTCTGATATAAAGCCCCTATTGGATTCTTCGGATGCGTAAAAGAAATTGCCTGTTTCAGC CAGAAGACTGGTGAAAACACATACATCAGACTATGTTGTGAGCCAGGTTGATTTTTTATTTTATTATATGCAGGTGAGTGTTGAAACTGT TAAAATTCCAATTTGTTTTCATTCAGTATTAGTTTAGTTCTAAATATAGCAAACCCCATCCAGGTGCTATCAGATGACCAGTTACTGCTT AGTTAACTAGGTGTAAAGTTTTACATATACATTAATGTCAATAGTTTATTACAAGTTGTGTAAAATGGACTCTAGTTTAATAATGGGGGA AAAAAGATTAGGTTGCTCCTGAAACTGACTGTAGAGCATGTAAAATGATTTTACTGGATTCTGTTCAACTGTAATCAATGAAAAAGATGT ACGTTGTAGACAAAGTTGCAGAATTAAAAAAAGAAATCTGCTTTTAATTTATTCTTTTTGTATTAAGAATTTGTATAGTACCTTTACATT >In-frame_FBXO18_ENST00000362091_chr10_5932309_+_FRMD4A_ENST00000378503_chr10_13717044_-_2119nt CTCGGGCTCCAGGTCCCGGCCAGAGGAGGAGCTCGCTGCCGGGGGACGCTGGGCTGAGCGGCCGGCGGCGCGGGCCCGGCGGCGGCGGCA GCGGGGTCCGGGTCCGGAGCGCCACAGTTCTCAGGAATCAGATAGCTCGCAGTCGGCCAAGAAGGACATGCTGGCTGCCTTGAAGTCCAG GCAGGAAGCTCTGGAGGAAACCCTGCGTCAGAGGCTGGAGGAACTGAAGAAGCTGTGTCTCCGAGAAGCTGAGCTCACGGGCAAGCTGCC AGTAGAATATCCCCTGGATCCAGGGGAGGAACCACCCATTGTTCGGAGAAGAATAGGAACAGCCTTCAAACTGGATGAACAGAAAATCCT GCCCAAAGGAGAGGAAGCTGAGCTGGAACGCCTGGAACGAGAGTTTGCCATTCAGTCCCAGATTACGGAGGCCGCCCGCCGCCTAGCCAG TGACCCCAACGTCAGCAAAAAACTGAAGAAACAAAGGAAAACCTCGTATCTGAATGCACTGAAGAAACTGCAGGAGATTGAAAATGCAAT CAATGAGAACCGCATCAAGTCTGGGAAGAAACCCACCCAGAGGGCTTCGCTGATCATAGACGATGGAAACATTGCCAGTGAAGACAGCTC CCTCTCAGATGCCCTTGTTCTTGAGGATGAAGACTCTCAGGTTACCAGCACAATATCCCCCCTACATTCTCCTCACAAGGGACTCCCTCC TCGGCCACCGTCGCACAACAGGCCTCCTCCTCCCCAGTCCCTGGAGGGACTCCGACAGATGCACTATCACCGCAACGACTATGACAAGTC ACCCATCAAGCCCAAAATGTGGAGTGAGTCCTCTTTAGATGAACCCTATGAGAAGGTCAAGAAGCGCTCCTCTCACAGCCATTCCAGCAG CCACAAGCGCTTCCCCAGCACAGGAAGCTGTGCGGAAGCCGGCGGAGGAAGCAACTCCTTGCAGAACAGCCCCATCCGCGGCCTCCCGCA CTGGAACTCCCAGTCCAGCATGCCGTCCACGCCAGACCTGCGGGTCCGGAGTCCCCACTACGTCCATTCCACGAGGTCGGTGGACATCAG CCCCACCCGACTGCACAGCCTCGCACTGCACTTTAGGCACCGGAGCTCCAGCCTGGAGTCCCAGGGCAAGCTCCTGGGCTCGGAAAACGA CACCGGGAGCCCCGACTTCTACACCCCGCGGACTCGTAGCAGCAACGGCTCAGACCCCATGGACGACTGCTCGTCGTGCACCAGCCACTC GAGCTCGGAGCACTACTACCCGGCGCAGATGAACGCCAACTACTCCACGCTGGCCGAGGACTCGCCGTCCAAGGCGCGCCAGAGGCAGAG GCAGCGGCAGCGGGCGGCGGGCGCACTGGGCTCAGCCAGCTCGGGCAGCATGCCCAACCTGGCGGCGCGCGGGGGTGCGGGGGGCGCGGG GGGCGCGGGGGGCGGTGTGTACCTGCACAGCCAGAGCCAGCCCAGCTCGCAGTACCGCATCAAGGAGTACCCGCTGTACATCGAGGGCGG CGCCACGCCCGTGGTGGTGCGCAGCCTGGAGAGCGACCAGGAGGGCCACTACAGCGTCAAGGCTCAGTTCAAGACGTCCAACTCCTACAC GGCGGGCGGCCTGTTCAAGGAGAGCTGGCGCGGCGGCGGCGGCGACGAGGGCGACACGGGCCGCCTGACGCCGTCGCGATCGCAGATCCT GCGGACTCCGTCGCTGGGCCGCGAGGGCGCCCACGACAAGGGCGCGGGCCGTGCCGCCGTCTCAGACGAGCTGCGCCAGTGGTACCAGCG TTCCACCGCCTCGCACAAGGAGCACAGCCGCCTGTCGCACACCAGCTCCACCTCCTCGGACAGCGGCTCGCAGTACAGCACCTCCTCCCA GAGCACCTTCGTGGCGCACAGCAGGGTCACCAGGATGCCCCAGATGTGCAAGGCCACGTCAGCTGCCTTACCTCAAAGCCAGAGAAGCTC GACACCGTCAAGTGAAATTGGAGCCACCCCCCCAAGCAGCCCCCACCACATCCTAACCTGGCAGACTGGAGAAGCAACAGAAAACTCACC |
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FusionGenePPI for FBXO18_FRMD4A |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FBXO18 | SKP1, CUL1, RBX1, HSP90AA1, RAD51, RPA1, RPA2, RPA3, PCNA, DTL, ZDHHC17, ESR1, PRR3, ILKAP, RALA, SYNCRIP, MRRF, UBC | FRMD4A | HNRNPA1, TRAF3IP1, YEATS4, WDR83 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FBXO18_FRMD4A |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FBXO18_FRMD4A |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | FRMD4A | C0236969 | Substance-Related Disorders | 1 | CTD_human |
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