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Fusion gene ID: 13136 |
FusionGeneSummary for FBXL7_NRD1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FBXL7_NRD1 | Fusion gene ID: 13136 | Hgene | Tgene | Gene symbol | FBXL7 | NRD1 | Gene ID | 23194 | 4898 |
| Gene name | F-box and leucine rich repeat protein 7 | nardilysin convertase | |
| Synonyms | FBL6|FBL7 | NRD1|hNRD1|hNRD2 | |
| Cytomap | 5p15.1 | 1p32.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | F-box/LRR-repeat protein 7F-box protein Fbl7 | nardilysinNRD convertasenardilysin (N-arginine dibasic convertase) | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9UJT9 | ||
| Ensembl transtripts involved in fusion gene | ENST00000504595, ENST00000510662, ENST00000329673, | ENST00000354831, ENST00000352171, ENST00000485608, ENST00000539524, ENST00000544028, | |
| Fusion gene scores | * DoF score | 10 X 5 X 5=250 | 4 X 3 X 3=36 |
| # samples | 11 | 4 | |
| ** MAII score | log2(11/250*10)=-1.18442457113743 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: FBXL7 [Title/Abstract] AND NRD1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | NRD1 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis | 18355445 |
| Tgene | NRD1 | GO:0052548 | regulation of endopeptidase activity | 18355445 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A2IZ-01A | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000504595 | ENST00000354831 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| In-frame | ENST00000504595 | ENST00000352171 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| 5CDS-5UTR | ENST00000504595 | ENST00000485608 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| 5CDS-5UTR | ENST00000504595 | ENST00000539524 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| 5CDS-5UTR | ENST00000504595 | ENST00000544028 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| 5UTR-3CDS | ENST00000510662 | ENST00000354831 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| 5UTR-3CDS | ENST00000510662 | ENST00000352171 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| 5UTR-5UTR | ENST00000510662 | ENST00000485608 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| 5UTR-5UTR | ENST00000510662 | ENST00000539524 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| 5UTR-5UTR | ENST00000510662 | ENST00000544028 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| In-frame | ENST00000329673 | ENST00000354831 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| In-frame | ENST00000329673 | ENST00000352171 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| 5CDS-5UTR | ENST00000329673 | ENST00000485608 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| 5CDS-5UTR | ENST00000329673 | ENST00000539524 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
| 5CDS-5UTR | ENST00000329673 | ENST00000544028 | FBXL7 | chr5 | 15616181 | + | NRD1 | chr1 | 52299842 | - |
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FusionProtFeatures for FBXL7_NRD1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FBXL7 | NRD1 |
| Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediatesthe ubiquitination and subsequent proteasomal degradation of AURKAduring mitosis, causing mitotic arrest. {ECO:0000250}. | Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 111_157 | 42 | 492 | Domain | F-box |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 170_195 | 42 | 492 | Repeat | Note=LRR 1 |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 196_221 | 42 | 492 | Repeat | Note=LRR 2 |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 222_247 | 42 | 492 | Repeat | Note=LRR 3 |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 253_281 | 42 | 492 | Repeat | Note=LRR 4 |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 282_307 | 42 | 492 | Repeat | Note=LRR 5 |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 308_333 | 42 | 492 | Repeat | Note=LRR 6 |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 334_359 | 42 | 492 | Repeat | Note=LRR 7 |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 360_385 | 42 | 492 | Repeat | Note=LRR 8 |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 386_411 | 42 | 492 | Repeat | Note=LRR 9 |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 412_437 | 42 | 492 | Repeat | Note=LRR 10 |
| Hgene | >FBXL7 | chr5:15616181 | chr1:52299842 | ENST00000504595 | + | 2 | 4 | 438_463 | 42 | 492 | Repeat | Note=LRR 11 |
| Tgene | NRD1 | chr5:15616181 | chr1:52299842 | ENST00000352171 | - | 2 | 31 | 142_200 | 237 | 1152 | Compositional bias | Note=Asp/Glu-rich (highly acidic) |
| Tgene | NRD1 | chr5:15616181 | chr1:52299842 | ENST00000352171 | - | 2 | 31 | 144_153 | 237 | 1152 | Compositional bias | Note=Poly-Glu |
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FusionGeneSequence for FBXL7_NRD1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FBXL7_ENST00000504595_chr5_15616181_+_NRD1_ENST00000354831_chr1_52299842_-_957aa MGANNGKQYGSEGKGSSSISSDVSSSTDHTPTKAQKNVATSEVVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKE ALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYS SHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLV GHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHY QEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWN SNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHN LAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYAR WSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGD ANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEK IENLTEEAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGYGKYEL >In-frame_FBXL7_ENST00000504595_chr5_15616181_+_NRD1_ENST00000352171_chr1_52299842_-_957aa MGANNGKQYGSEGKGSSSISSDVSSSTDHTPTKAQKNVATSEVVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKE ALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYS SHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLV GHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHY QEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWN SNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHN LAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYAR WSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGD ANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEK IENLTEEAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGYGKYEL >In-frame_FBXL7_ENST00000329673_chr5_15616181_+_NRD1_ENST00000354831_chr1_52299842_-_945aa GKGSSSISSDVSSSTDHTPTKAQKNVATSEVVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHP LMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKE TLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFL RKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVEN MCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLP AENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQ LEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMD GLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSG TRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQ VTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSN >In-frame_FBXL7_ENST00000329673_chr5_15616181_+_NRD1_ENST00000352171_chr1_52299842_-_945aa GKGSSSISSDVSSSTDHTPTKAQKNVATSEVVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHP LMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKE TLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFL RKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVEN MCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLP AENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQ LEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMD GLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSG TRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQ VTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSN |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FBXL7_ENST00000504595_chr5_15616181_+_NRD1_ENST00000354831_chr1_52299842_-_2871nt ATGGGCGCGAACAATGGCAAACAGTACGGCAGTGAGGGCAAAGGCAGCTCGAGCATCTCATCTGACGTGAGTTCAAGTACAGATCACACG CCCACTAAAGCCCAGAAGAATGTGGCTACCAGCGAAGTGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTC CTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAA GCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATAT CAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGG GGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCT TCTCATTACATGACTTTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAAC AATGGGTTACCCAGACCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGA AAAATTCATGCTCTGACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTT GGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTT GAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTC TTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTAC CAAGAACAGACAGATCCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAG CTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCT AATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAAT AGTAATTTCGAATTAAATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCG GAAACAGAATACCCAGTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATAT ATACGTTTCCATCTAATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAAC CTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGA TTTAACCACAAACTACCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACT GAGCAGTTGAAGAAGACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGT TGGTCTATGATTGACAAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTC TTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCT CTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGAT GCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGTACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCACATGGAA GAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACCCTTGGGTACCATGTCTACCCTACCTGTAGGAACACATCCGGGATTCTAGGATTT TCTGTCACTGTGGGGACTCAGGCAACCAAATACAATTCTGAAGTTGTTGATAAGAAGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAG ATTGAGAACCTCACTGAAGAGGCATTCAACACCCAGGTCACAGCTCTCATCAAGCTGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAG GTGGATAGGAACTGGAATGAAGTGGTTACACAGCAGTACCTCTTTGACCGCCTTGCCCACGAGATTGAAGCACTGAAGTCATTCTCAAAA TCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGGCCAGGAAGTAAAATGCTCAGCGTTCATGTTGTTGGATATGGGAAGTATGAACTG GAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAATTCTTCTTGTGAAGTGATGCAGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCA >In-frame_FBXL7_ENST00000504595_chr5_15616181_+_NRD1_ENST00000352171_chr1_52299842_-_2871nt ATGGGCGCGAACAATGGCAAACAGTACGGCAGTGAGGGCAAAGGCAGCTCGAGCATCTCATCTGACGTGAGTTCAAGTACAGATCACACG CCCACTAAAGCCCAGAAGAATGTGGCTACCAGCGAAGTGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTC CTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAA GCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATAT CAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGG GGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCT TCTCATTACATGACTTTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAAC AATGGGTTACCCAGACCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGA AAAATTCATGCTCTGACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTT GGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTT GAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTC TTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTAC CAAGAACAGACAGATCCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAG CTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCT AATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAAT AGTAATTTCGAATTAAATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCG GAAACAGAATACCCAGTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATAT ATACGTTTCCATCTAATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAAC CTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGA TTTAACCACAAACTACCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACT GAGCAGTTGAAGAAGACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGT TGGTCTATGATTGACAAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTC TTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCT CTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGAT GCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGTACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCACATGGAA GAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACCCTTGGGTACCATGTCTACCCTACCTGTAGGAACACATCCGGGATTCTAGGATTT TCTGTCACTGTGGGGACTCAGGCAACCAAATACAATTCTGAAGTTGTTGATAAGAAGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAG ATTGAGAACCTCACTGAAGAGGCATTCAACACCCAGGTCACAGCTCTCATCAAGCTGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAG GTGGATAGGAACTGGAATGAAGTGGTTACACAGCAGTACCTCTTTGACCGCCTTGCCCACGAGATTGAAGCACTGAAGTCATTCTCAAAA TCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGGCCAGGAAGTAAAATGCTCAGCGTTCATGTTGTTGGATATGGGAAGTATGAACTG GAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAATTCTTCTTGTGAAGTGATGCAGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCA >In-frame_FBXL7_ENST00000329673_chr5_15616181_+_NRD1_ENST00000354831_chr1_52299842_-_2835nt GGCAAAGGCAGCTCGAGCATCTCATCTGACGTGAGTTCAAGTACAGATCACACGCCCACTAAAGCCCAGAAGAATGTGGCTACCAGCGAA GTGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACT GATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCA CTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAA ATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAG AATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGAA ACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAACG GATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCCT CCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTT AGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCT ATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCA GAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAAC ATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAA GCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTT GGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCCA GCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCCA CAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAAA TCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAG CTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCATT ATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCATC AAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGAC GGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGC ACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTA GAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGT ACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACC CTTGGGTACCATGTCTACCCTACCTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAATACAAT TCTGAAGTTGTTGATAAGAAGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACACCCAG GTCACAGCTCTCATCAAGCTGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACACAGCAG TACCTCTTTGACCGCCTTGCCCACGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGG CCAGGAAGTAAAATGCTCAGCGTTCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAAT TCTTCTTGTGAAGTGATGCAGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGGCTTTC >In-frame_FBXL7_ENST00000329673_chr5_15616181_+_NRD1_ENST00000352171_chr1_52299842_-_2835nt GGCAAAGGCAGCTCGAGCATCTCATCTGACGTGAGTTCAAGTACAGATCACACGCCCACTAAAGCCCAGAAGAATGTGGCTACCAGCGAA GTGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACT GATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCA CTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAA ATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAG AATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGAA ACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAACG GATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCCT CCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTT AGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCT ATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCA GAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAAC ATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAA GCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTT GGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCCA GCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCCA CAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAAA TCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAG CTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCATT ATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCATC AAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGAC GGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGC ACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTA GAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGT ACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACC CTTGGGTACCATGTCTACCCTACCTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAATACAAT TCTGAAGTTGTTGATAAGAAGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACACCCAG GTCACAGCTCTCATCAAGCTGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACACAGCAG TACCTCTTTGACCGCCTTGCCCACGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGG CCAGGAAGTAAAATGCTCAGCGTTCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAAT TCTTCTTGTGAAGTGATGCAGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGGCTTTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FBXL7_ENST00000504595_chr5_15616181_+_NRD1_ENST00000354831_chr1_52299842_-_3397nt TCACTCGCTCCGGGGACCCGCAACAAGTGGCCGCCGCGCCCTCCCCGGGGAAGCCGCGGGCGCGCAGGGGCAGCCGAAGGAGGCGGTCGA GCCGCGGAGCCCAGGGGCCTGCCCGGCTCAGCGCCCACCGGAGGGGATCGGGGCGGGCGGATGGGGACCCGGCGGCGGCGGCGCGGTGAG CCTCTGGGCGGCCCCGGGGCGCGGGCTGTGCGCGGCGCTGCGCCCGCCGGCCCCCAGCGCGGATTGTAAGTGCTGCAGCTGTGCCCGGCC CCGCCTGGAGCCACCGGGGGTGCCAGGAGGGGACGCAGCACCCCCTCCCACTGGAGTGCGGGGACCTCTCCAGGCCGGAGGTCGGCCCCG GAGCTTGGGGGGGATGTGCAGCTAACGGTCCCGTCGGGCGGGCTTTCCTCGGGCCGAGCGCGCAGGACGTGCGCCGCAGCTATGGAGTGT CCCGGGAGACGGCGGGCATGACGGCTACAGGATGGGCGCGAACAATGGCAAACAGTACGGCAGTGAGGGCAAAGGCAGCTCGAGCATCTC ATCTGACGTGAGTTCAAGTACAGATCACACGCCCACTAAAGCCCAGAAGAATGTGGCTACCAGCGAAGTGGTATTCATGGGTAGTTTGAA ATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCTTTCA GTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAATTGA CCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTGCTAG ACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATGCTAG ATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAAAGTG GGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAGCATT TAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACAGGGT GAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTCTTGC ACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGGGTTA TGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAGAGAT TCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGCTGTA CCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTCCTCA AAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAGAAGA TATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAGCCAC GGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATAAGAA AGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCCTCTT TGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAGCTGG AGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGTTCAA TTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCAAAGA TGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTCTGCT GAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCCTGAA ATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACCATCT ATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGTACCAGGAGTCTAAGAGAATATAC GCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACCCTTGGGTACCATGTCTACCCTAC CTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAATACAATTCTGAAGTTGTTGATAAGAAGAT AGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACACCCAGGTCACAGCTCTCATCAAGCTGAA GGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACACAGCAGTACCTCTTTGACCGCCTTGCCCA CGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGGCCAGGAAGTAAAATGCTCAGCGT TCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAATTCTTCTTGTGAAGTGATGCAGCT GACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGGCTTTCACAACAACACTCAACCTTCTCCC >In-frame_FBXL7_ENST00000504595_chr5_15616181_+_NRD1_ENST00000352171_chr1_52299842_-_3397nt TCACTCGCTCCGGGGACCCGCAACAAGTGGCCGCCGCGCCCTCCCCGGGGAAGCCGCGGGCGCGCAGGGGCAGCCGAAGGAGGCGGTCGA GCCGCGGAGCCCAGGGGCCTGCCCGGCTCAGCGCCCACCGGAGGGGATCGGGGCGGGCGGATGGGGACCCGGCGGCGGCGGCGCGGTGAG CCTCTGGGCGGCCCCGGGGCGCGGGCTGTGCGCGGCGCTGCGCCCGCCGGCCCCCAGCGCGGATTGTAAGTGCTGCAGCTGTGCCCGGCC CCGCCTGGAGCCACCGGGGGTGCCAGGAGGGGACGCAGCACCCCCTCCCACTGGAGTGCGGGGACCTCTCCAGGCCGGAGGTCGGCCCCG GAGCTTGGGGGGGATGTGCAGCTAACGGTCCCGTCGGGCGGGCTTTCCTCGGGCCGAGCGCGCAGGACGTGCGCCGCAGCTATGGAGTGT CCCGGGAGACGGCGGGCATGACGGCTACAGGATGGGCGCGAACAATGGCAAACAGTACGGCAGTGAGGGCAAAGGCAGCTCGAGCATCTC ATCTGACGTGAGTTCAAGTACAGATCACACGCCCACTAAAGCCCAGAAGAATGTGGCTACCAGCGAAGTGGTATTCATGGGTAGTTTGAA ATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCTTTCA GTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAATTGA CCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTGCTAG ACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATGCTAG ATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAAAGTG GGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAGCATT TAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACAGGGT GAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTCTTGC ACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGGGTTA TGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAGAGAT TCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGCTGTA CCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTCCTCA AAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAGAAGA TATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAGCCAC GGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATAAGAA AGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCCTCTT TGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAGCTGG AGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGTTCAA TTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCAAAGA TGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTCTGCT GAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCCTGAA ATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACCATCT ATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGTACCAGGAGTCTAAGAGAATATAC GCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACCCTTGGGTACCATGTCTACCCTAC CTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAATACAATTCTGAAGTTGTTGATAAGAAGAT AGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACACCCAGGTCACAGCTCTCATCAAGCTGAA GGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACACAGCAGTACCTCTTTGACCGCCTTGCCCA CGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGGCCAGGAAGTAAAATGCTCAGCGT TCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAATTCTTCTTGTGAAGTGATGCAGCT GACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGGCTTTCACAACAACACTCAACCTTCTCCC >In-frame_FBXL7_ENST00000329673_chr5_15616181_+_NRD1_ENST00000354831_chr1_52299842_-_2880nt GGCAAAGGCAGCTCGAGCATCTCATCTGACGTGAGTTCAAGTACAGATCACACGCCCACTAAAGCCCAGAAGAATGTGGCTACCAGCGAA GTGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACT GATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCA CTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAA ATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAG AATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGAA ACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAACG GATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCCT CCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTT AGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCT ATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCA GAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAAC ATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAA GCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTT GGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCCA GCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCCA CAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAAA TCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAG CTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCATT ATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCATC AAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGAC GGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGC ACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTA GAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGT ACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACC CTTGGGTACCATGTCTACCCTACCTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAATACAAT TCTGAAGTTGTTGATAAGAAGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACACCCAG GTCACAGCTCTCATCAAGCTGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACACAGCAG TACCTCTTTGACCGCCTTGCCCACGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGG CCAGGAAGTAAAATGCTCAGCGTTCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAAT TCTTCTTGTGAAGTGATGCAGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGGCTTTC ACAACAACACTCAACCTTCTCCCCTACCATAAAATAGTCAAATAAATAAACTGCAGTCACGTTGGCCTGAAGCAATGTGTATTTTAAAAT >In-frame_FBXL7_ENST00000329673_chr5_15616181_+_NRD1_ENST00000352171_chr1_52299842_-_2880nt GGCAAAGGCAGCTCGAGCATCTCATCTGACGTGAGTTCAAGTACAGATCACACGCCCACTAAAGCCCAGAAGAATGTGGCTACCAGCGAA GTGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACT GATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCA CTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAA ATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAG AATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGAA ACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAACG GATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCCT CCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTT AGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCT ATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCA GAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAAC ATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAA GCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTT GGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCCA GCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCCA CAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAAA TCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAG CTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCATT ATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCATC AAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGAC GGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGC ACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTA GAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGT ACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACC CTTGGGTACCATGTCTACCCTACCTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAATACAAT TCTGAAGTTGTTGATAAGAAGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACACCCAG GTCACAGCTCTCATCAAGCTGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACACAGCAG TACCTCTTTGACCGCCTTGCCCACGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGG CCAGGAAGTAAAATGCTCAGCGTTCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAAT TCTTCTTGTGAAGTGATGCAGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGGCTTTC ACAACAACACTCAACCTTCTCCCCTACCATAAAATAGTCAAATAAATAAACTGCAGTCACGTTGGCCTGAAGCAATGTGTATTTTAAAAT |
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FusionGenePPI for FBXL7_NRD1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FBXL7 | SKP1, APP, WDR48, ZRANB2, AHCYL1, FBXL18, CUL1, BIRC5 | NRD1 | HBEGF, BTRC, FBXW11, UIMC1, HIST2H3C, MAD1L1, COBLL1, NCOR1, UACA, IQGAP1, HDAC3, NCOR2, TBL1X, NRD1, MOB1A, STK3, MOB2, HSPB1, PNKP, DNAJC7, ELAC2, P3H1, SETSIP, MSH2, NSUN2, PDIA6, PFDN5, PPP1R12A, PPP2CA, PPP2R2A, PPP3CA, PUS1, XPO5, YARS, PFDN1, TSN, MOV10, NXF1, FMR1NB, ZNF707, LUC7L, SEPT1, KPNA3, NTRK1, ATM, LGALS3BP, PDGFRA, ERP44, PCDHB15, KIF7, CHCHD2, ATP5A1, APOOL, COQ7, COQ6, WBSCR16, LYRM4, C6orf203, CHCHD1, NME4, OCIAD1, ACP6, ADCK2, TRUB2, DHRS4, CISD3, OPA3, BOLA3, NLGN3, AURKAIP1, TMEM184A, DEF8, BATF3, METTL25, CDRT15, CLK3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FBXL7_NRD1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FBXL7_NRD1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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