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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 13087

FusionGeneSummary for FBXL20_GDPD5

check button Fusion gene summary
Fusion gene informationFusion gene name: FBXL20_GDPD5
Fusion gene ID: 13087
HgeneTgene
Gene symbol

FBXL20

GDPD5

Gene ID

84961

81544

Gene nameF-box and leucine rich repeat protein 20glycerophosphodiester phosphodiesterase domain containing 5
SynonymsFbl2|Fbl20GDE2|PP1665
Cytomap

17q12

11q13.4-q13.5

Type of geneprotein-codingprotein-coding
DescriptionF-box/LRR-repeat protein 20F-box protein FBL2glycerophosphodiester phosphodiesterase domain-containing protein 5glycerophosphodiester phosphodiesterase 2
Modification date2018052320180519
UniProtAcc

Q96IG2

Q8WTR4

Ensembl transtripts involved in fusion geneENST00000583610, ENST00000394294, 
ENST00000264658, ENST00000577399, 
ENST00000336898, ENST00000376282, 
ENST00000529095, ENST00000526177, 
ENST00000533784, ENST00000529721, 
ENST00000533805, ENST00000443276, 
Fusion gene scores* DoF score40 X 12 X 14=67208 X 7 X 7=392
# samples 3813
** MAII scorelog2(38/6720*10)=-4.14438990933518
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/392*10)=-1.59234203108675
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FBXL20 [Title/Abstract] AND GDPD5 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVBRCATCGA-A1-A0SM-01AFBXL20chr17

37457254

-GDPD5chr11

75167861

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000583610ENST00000336898FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000583610ENST00000376282FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000583610ENST00000529095FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000583610ENST00000526177FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000583610ENST00000533784FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000583610ENST00000529721FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000583610ENST00000533805FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000583610ENST00000443276FBXL20chr17

37457254

-GDPD5chr11

75167861

-
In-frameENST00000394294ENST00000336898FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000394294ENST00000376282FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000394294ENST00000529095FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000394294ENST00000526177FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000394294ENST00000533784FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000394294ENST00000529721FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000394294ENST00000533805FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000394294ENST00000443276FBXL20chr17

37457254

-GDPD5chr11

75167861

-
In-frameENST00000264658ENST00000336898FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000264658ENST00000376282FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000264658ENST00000529095FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000264658ENST00000526177FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000264658ENST00000533784FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000264658ENST00000529721FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000264658ENST00000533805FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000264658ENST00000443276FBXL20chr17

37457254

-GDPD5chr11

75167861

-
In-frameENST00000577399ENST00000336898FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000577399ENST00000376282FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000577399ENST00000529095FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000577399ENST00000526177FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000577399ENST00000533784FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000577399ENST00000529721FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000577399ENST00000533805FBXL20chr17

37457254

-GDPD5chr11

75167861

-
5CDS-intronENST00000577399ENST00000443276FBXL20chr17

37457254

-GDPD5chr11

75167861

-

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FusionProtFeatures for FBXL20_GDPD5


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FBXL20

Q96IG2

GDPD5

Q8WTR4

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neuraltransmission (By similarity). {ECO:0000250}. Promotes neurite formation. Cooperates with PRDX1 todrive postmitotic motor neuron differentiation. Theglycerophosphodiester phosphodiesterase activity may be requiredfor its role in neuronal differentiation. May contribute to theosmotic regulation of cellular glycerophosphocholine.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-41522_6878437DomainF-box
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-41422_6878405DomainF-box
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-41622_6878411DomainF-box
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-417228_485105606DomainNote=GP-PDE
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-013228_485-253487DomainNote=GP-PDE
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-013228_485-627468DomainNote=GP-PDE
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-518228_485105606DomainNote=GP-PDE
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-012228_485-38487DomainNote=GP-PDE
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-012228_485-159361DomainNote=GP-PDE
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-417111_125105606Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-417147_160105606Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-417182_192105606Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-417214_496105606Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-417518_605105606Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-013111_125-253487Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-013147_160-253487Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-013182_192-253487Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-0131_42-253487Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-013214_496-253487Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-013518_605-253487Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-01364_89-253487Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-013111_125-627468Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-013147_160-627468Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-013182_192-627468Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-0131_42-627468Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-013214_496-627468Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-013518_605-627468Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-01364_89-627468Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-518111_125105606Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-518147_160105606Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-518182_192105606Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-518214_496105606Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-518518_605105606Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-012111_125-38487Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-012147_160-38487Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-012182_192-38487Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-0121_42-38487Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-012214_496-38487Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-012518_605-38487Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-01264_89-38487Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-012111_125-159361Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-012147_160-159361Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-012182_192-159361Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-0121_42-159361Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-012214_496-159361Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-012518_605-159361Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-01264_89-159361Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-417126_146105606TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-417161_181105606TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-417193_213105606TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-417497_517105606TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-013126_146-253487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-013161_181-253487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-013193_213-253487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-01343_63-253487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-013497_517-253487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000376282-01390_110-253487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-013126_146-627468TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-013161_181-627468TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-013193_213-627468TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-01343_63-627468TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-013497_517-627468TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000526177-01390_110-627468TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-518126_146105606TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-518161_181105606TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-518193_213105606TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-518497_517105606TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-012126_146-38487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-012161_181-38487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-012193_213-38487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-01243_63-38487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-012497_517-38487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533784-01290_110-38487TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-012126_146-159361TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-012161_181-159361TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-012193_213-159361TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-01243_63-159361TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-012497_517-159361TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000533805-01290_110-159361TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415101_12678437RepeatNote=LRR 2
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415127_15278437RepeatNote=LRR 3
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415153_17878437RepeatNote=LRR 4
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415179_20478437RepeatNote=LRR 5
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415205_23078437RepeatNote=LRR 6
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415231_25678437RepeatNote=LRR 7
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415257_28278437RepeatNote=LRR 8
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415283_30878437RepeatNote=LRR 9
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415309_33478437RepeatNote=LRR 10
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415335_36378437RepeatNote=LRR 11
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415364_38878437RepeatNote=LRR 12
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-415389_41478437RepeatNote=LRR 13
HgeneFBXL20chr17:37457254chr11:75167861ENST00000264658-41574_10078437RepeatNote=LRR 1
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414101_12678405RepeatNote=LRR 2
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414127_15278405RepeatNote=LRR 3
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414153_17878405RepeatNote=LRR 4
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414179_20478405RepeatNote=LRR 5
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414205_23078405RepeatNote=LRR 6
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414231_25678405RepeatNote=LRR 7
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414257_28278405RepeatNote=LRR 8
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414283_30878405RepeatNote=LRR 9
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414309_33478405RepeatNote=LRR 10
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414335_36378405RepeatNote=LRR 11
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414364_38878405RepeatNote=LRR 12
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-414389_41478405RepeatNote=LRR 13
HgeneFBXL20chr17:37457254chr11:75167861ENST00000394294-41474_10078405RepeatNote=LRR 1
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416101_12678411RepeatNote=LRR 2
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416127_15278411RepeatNote=LRR 3
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416153_17878411RepeatNote=LRR 4
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416179_20478411RepeatNote=LRR 5
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416205_23078411RepeatNote=LRR 6
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416231_25678411RepeatNote=LRR 7
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416257_28278411RepeatNote=LRR 8
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416283_30878411RepeatNote=LRR 9
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416309_33478411RepeatNote=LRR 10
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416335_36378411RepeatNote=LRR 11
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416364_38878411RepeatNote=LRR 12
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-416389_41478411RepeatNote=LRR 13
HgeneFBXL20chr17:37457254chr11:75167861ENST00000583610-41674_10078411RepeatNote=LRR 1
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-4171_42105606Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-41764_89105606Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-5181_42105606Topological domainCytoplasmic
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-51864_89105606Topological domainExtracellular
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-41743_63105606TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000336898-41790_110105606TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-51843_63105606TransmembraneHelical
TgeneGDPD5chr17:37457254chr11:75167861ENST00000529721-51890_110105606TransmembraneHelical


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FusionGeneSequence for FBXL20_GDPD5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_FBXL20_ENST00000583610_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_579aa
MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEVLALCHIAVGQQ
MNLHWLHKIGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHVGAVAAVTMLSWIVAGQFARAERTSSQVTILCTFFTVVFALY
LAPLTISSPCIMEKKDLGPKPALIGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFPELARRPA
SMLNWTTLQRLNAGQWFLKTDPFWTASSLSPSDHREAQNQSICSLAELLELAKGNATLLLNLRDPPREHPYRSSFINVTLEAVLHSGFPQ
HQVMWLPSRQRPLVRKVAPGFQQTSGSKEAVASLRRGHIQRLNLRYTQVSRQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTSDN
SHALSQVPSPLWIMPPDEYCLMWVTADLVSFTLIVGIFVLQKWRLGGIRSYNPEQIMLSAAVRRTSRDVSIMKEKLIFSEISDGVEVSDV

>In-frame_FBXL20_ENST00000394294_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_579aa
MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEVLALCHIAVGQQ
MNLHWLHKIGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHVGAVAAVTMLSWIVAGQFARAERTSSQVTILCTFFTVVFALY
LAPLTISSPCIMEKKDLGPKPALIGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFPELARRPA
SMLNWTTLQRLNAGQWFLKTDPFWTASSLSPSDHREAQNQSICSLAELLELAKGNATLLLNLRDPPREHPYRSSFINVTLEAVLHSGFPQ
HQVMWLPSRQRPLVRKVAPGFQQTSGSKEAVASLRRGHIQRLNLRYTQVSRQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTSDN
SHALSQVPSPLWIMPPDEYCLMWVTADLVSFTLIVGIFVLQKWRLGGIRSYNPEQIMLSAAVRRTSRDVSIMKEKLIFSEISDGVEVSDV

>In-frame_FBXL20_ENST00000264658_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_579aa
MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEVLALCHIAVGQQ
MNLHWLHKIGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHVGAVAAVTMLSWIVAGQFARAERTSSQVTILCTFFTVVFALY
LAPLTISSPCIMEKKDLGPKPALIGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFPELARRPA
SMLNWTTLQRLNAGQWFLKTDPFWTASSLSPSDHREAQNQSICSLAELLELAKGNATLLLNLRDPPREHPYRSSFINVTLEAVLHSGFPQ
HQVMWLPSRQRPLVRKVAPGFQQTSGSKEAVASLRRGHIQRLNLRYTQVSRQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTSDN
SHALSQVPSPLWIMPPDEYCLMWVTADLVSFTLIVGIFVLQKWRLGGIRSYNPEQIMLSAAVRRTSRDVSIMKEKLIFSEISDGVEVSDV

>In-frame_FBXL20_ENST00000577399_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_581aa
MAPSRDRLLHFGFKATMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEVLALCHIAVG
QQMNLHWLHKIGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHVGAVAAVTMLSWIVAGQFARAERTSSQVTILCTFFTVVFA
LYLAPLTISSPCIMEKKDLGPKPALIGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFPELARR
PASMLNWTTLQRLNAGQWFLKTDPFWTASSLSPSDHREAQNQSICSLAELLELAKGNATLLLNLRDPPREHPYRSSFINVTLEAVLHSGF
PQHQVMWLPSRQRPLVRKVAPGFQQTSGSKEAVASLRRGHIQRLNLRYTQVSRQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTS
DNSHALSQVPSPLWIMPPDEYCLMWVTADLVSFTLIVGIFVLQKWRLGGIRSYNPEQIMLSAAVRRTSRDVSIMKEKLIFSEISDGVEVS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_FBXL20_ENST00000583610_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_1737nt
ATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGATGTTCTCAAATAGTGATGAAGCTGTAATCAATAAAAAACTTCCCAAA
GAACTCCTGTTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTCTCCAGGGCCTGGAATGTTCTGGCTCTG
GATGGCAGTAACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGTCCTGGCACTATGTCACATTGCCGTGGGGCAGCAG
ATGAACCTGCACTGGCTGCACAAGATCGGGCTGGTGGTCATCCTGGCTTCCACGGTGGTGGCCATGTCGGCCGTGGCCCAGCTGTGGGAG
GACGAGTGGGAGGTGCTGCTGATCTCCCTGCAGGGCACAGCGCCATTCCTGCATGTGGGGGCTGTGGCAGCAGTCACCATGCTCTCCTGG
ATCGTGGCAGGACAGTTCGCCCGCGCAGAGCGGACCTCCTCCCAGGTGACCATTCTCTGTACCTTCTTCACCGTGGTGTTTGCCCTCTAC
CTGGCCCCTCTCACCATCTCCTCTCCCTGCATCATGGAGAAGAAAGACCTCGGCCCCAAGCCTGCTCTCATTGGCCACCGCGGGGCCCCC
ATGCTGGCTCCAGAGCACACGCTCATGTCCTTCCGGAAGGCCCTCGAGCAGAAGCTGTACGGGCTCCAGGCTGACATTACCATCAGCCTG
GACGGCGTGCCCTTCCTCATGCATGACACCACCCTGCGGCGCACCACCAACGTGGAGGAGGAGTTCCCGGAGCTGGCCCGCAGGCCTGCC
TCCATGCTTAACTGGACCACCCTGCAGAGACTCAACGCTGGCCAGTGGTTCCTGAAGACTGACCCCTTCTGGACAGCCAGCTCCCTGTCA
CCCTCCGACCACAGAGAGGCCCAGAACCAGTCCATCTGCAGCCTGGCAGAGCTCCTGGAGCTGGCCAAGGGCAATGCCACACTGCTGCTC
AACCTGCGTGACCCGCCCCGGGAGCACCCCTACCGCAGCAGTTTTATCAACGTGACTCTGGAGGCCGTGCTGCACTCCGGCTTCCCCCAG
CACCAGGTCATGTGGCTGCCTAGCAGGCAGAGGCCCCTGGTGCGGAAGGTGGCTCCCGGCTTCCAACAGACATCAGGCTCCAAGGAGGCA
GTCGCCAGCCTGCGGAGAGGCCACATCCAGCGGCTGAACCTGCGCTACACTCAGGTGTCCCGCCAGGAGCTCAGGGACTACGCGTCCTGG
AACCTGAGTGTGAACCTCTACACAGTCAACGCACCGTGGCTCTTCTCCCTGCTGTGGTGTGCGGGGGTCCCATCCGTCACCTCTGACAAC
TCCCACGCCCTGTCCCAGGTGCCTTCCCCCCTCTGGATCATGCCCCCGGACGAGTACTGTCTCATGTGGGTCACTGCCGACCTGGTCTCC
TTCACCCTCATCGTGGGCATCTTCGTGCTCCAGAAGTGGCGCCTGGGTGGCATACGGAGCTACAACCCTGAGCAGATCATGCTGAGTGCT
GCGGTGCGCCGGACCAGCCGGGACGTCAGCATCATGAAGGAGAAGCTTATTTTCTCAGAGATCAGCGATGGTGTAGAGGTCTCCGATGTG
CTCTCCGTATGTTCAGACAACAGTTATGACACATATGCCAACAGCACCGCCACCCCTGTGGGCCCCCGAGGGGGTGGCAGCCACACCAAG

>In-frame_FBXL20_ENST00000394294_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_1737nt
ATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGATGTTCTCAAATAGTGATGAAGCTGTAATCAATAAAAAACTTCCCAAA
GAACTCCTGTTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTCTCCAGGGCCTGGAATGTTCTGGCTCTG
GATGGCAGTAACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGTCCTGGCACTATGTCACATTGCCGTGGGGCAGCAG
ATGAACCTGCACTGGCTGCACAAGATCGGGCTGGTGGTCATCCTGGCTTCCACGGTGGTGGCCATGTCGGCCGTGGCCCAGCTGTGGGAG
GACGAGTGGGAGGTGCTGCTGATCTCCCTGCAGGGCACAGCGCCATTCCTGCATGTGGGGGCTGTGGCAGCAGTCACCATGCTCTCCTGG
ATCGTGGCAGGACAGTTCGCCCGCGCAGAGCGGACCTCCTCCCAGGTGACCATTCTCTGTACCTTCTTCACCGTGGTGTTTGCCCTCTAC
CTGGCCCCTCTCACCATCTCCTCTCCCTGCATCATGGAGAAGAAAGACCTCGGCCCCAAGCCTGCTCTCATTGGCCACCGCGGGGCCCCC
ATGCTGGCTCCAGAGCACACGCTCATGTCCTTCCGGAAGGCCCTCGAGCAGAAGCTGTACGGGCTCCAGGCTGACATTACCATCAGCCTG
GACGGCGTGCCCTTCCTCATGCATGACACCACCCTGCGGCGCACCACCAACGTGGAGGAGGAGTTCCCGGAGCTGGCCCGCAGGCCTGCC
TCCATGCTTAACTGGACCACCCTGCAGAGACTCAACGCTGGCCAGTGGTTCCTGAAGACTGACCCCTTCTGGACAGCCAGCTCCCTGTCA
CCCTCCGACCACAGAGAGGCCCAGAACCAGTCCATCTGCAGCCTGGCAGAGCTCCTGGAGCTGGCCAAGGGCAATGCCACACTGCTGCTC
AACCTGCGTGACCCGCCCCGGGAGCACCCCTACCGCAGCAGTTTTATCAACGTGACTCTGGAGGCCGTGCTGCACTCCGGCTTCCCCCAG
CACCAGGTCATGTGGCTGCCTAGCAGGCAGAGGCCCCTGGTGCGGAAGGTGGCTCCCGGCTTCCAACAGACATCAGGCTCCAAGGAGGCA
GTCGCCAGCCTGCGGAGAGGCCACATCCAGCGGCTGAACCTGCGCTACACTCAGGTGTCCCGCCAGGAGCTCAGGGACTACGCGTCCTGG
AACCTGAGTGTGAACCTCTACACAGTCAACGCACCGTGGCTCTTCTCCCTGCTGTGGTGTGCGGGGGTCCCATCCGTCACCTCTGACAAC
TCCCACGCCCTGTCCCAGGTGCCTTCCCCCCTCTGGATCATGCCCCCGGACGAGTACTGTCTCATGTGGGTCACTGCCGACCTGGTCTCC
TTCACCCTCATCGTGGGCATCTTCGTGCTCCAGAAGTGGCGCCTGGGTGGCATACGGAGCTACAACCCTGAGCAGATCATGCTGAGTGCT
GCGGTGCGCCGGACCAGCCGGGACGTCAGCATCATGAAGGAGAAGCTTATTTTCTCAGAGATCAGCGATGGTGTAGAGGTCTCCGATGTG
CTCTCCGTATGTTCAGACAACAGTTATGACACATATGCCAACAGCACCGCCACCCCTGTGGGCCCCCGAGGGGGTGGCAGCCACACCAAG

>In-frame_FBXL20_ENST00000264658_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_1737nt
ATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGATGTTCTCAAATAGTGATGAAGCTGTAATCAATAAAAAACTTCCCAAA
GAACTCCTGTTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTCTCCAGGGCCTGGAATGTTCTGGCTCTG
GATGGCAGTAACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGTCCTGGCACTATGTCACATTGCCGTGGGGCAGCAG
ATGAACCTGCACTGGCTGCACAAGATCGGGCTGGTGGTCATCCTGGCTTCCACGGTGGTGGCCATGTCGGCCGTGGCCCAGCTGTGGGAG
GACGAGTGGGAGGTGCTGCTGATCTCCCTGCAGGGCACAGCGCCATTCCTGCATGTGGGGGCTGTGGCAGCAGTCACCATGCTCTCCTGG
ATCGTGGCAGGACAGTTCGCCCGCGCAGAGCGGACCTCCTCCCAGGTGACCATTCTCTGTACCTTCTTCACCGTGGTGTTTGCCCTCTAC
CTGGCCCCTCTCACCATCTCCTCTCCCTGCATCATGGAGAAGAAAGACCTCGGCCCCAAGCCTGCTCTCATTGGCCACCGCGGGGCCCCC
ATGCTGGCTCCAGAGCACACGCTCATGTCCTTCCGGAAGGCCCTCGAGCAGAAGCTGTACGGGCTCCAGGCTGACATTACCATCAGCCTG
GACGGCGTGCCCTTCCTCATGCATGACACCACCCTGCGGCGCACCACCAACGTGGAGGAGGAGTTCCCGGAGCTGGCCCGCAGGCCTGCC
TCCATGCTTAACTGGACCACCCTGCAGAGACTCAACGCTGGCCAGTGGTTCCTGAAGACTGACCCCTTCTGGACAGCCAGCTCCCTGTCA
CCCTCCGACCACAGAGAGGCCCAGAACCAGTCCATCTGCAGCCTGGCAGAGCTCCTGGAGCTGGCCAAGGGCAATGCCACACTGCTGCTC
AACCTGCGTGACCCGCCCCGGGAGCACCCCTACCGCAGCAGTTTTATCAACGTGACTCTGGAGGCCGTGCTGCACTCCGGCTTCCCCCAG
CACCAGGTCATGTGGCTGCCTAGCAGGCAGAGGCCCCTGGTGCGGAAGGTGGCTCCCGGCTTCCAACAGACATCAGGCTCCAAGGAGGCA
GTCGCCAGCCTGCGGAGAGGCCACATCCAGCGGCTGAACCTGCGCTACACTCAGGTGTCCCGCCAGGAGCTCAGGGACTACGCGTCCTGG
AACCTGAGTGTGAACCTCTACACAGTCAACGCACCGTGGCTCTTCTCCCTGCTGTGGTGTGCGGGGGTCCCATCCGTCACCTCTGACAAC
TCCCACGCCCTGTCCCAGGTGCCTTCCCCCCTCTGGATCATGCCCCCGGACGAGTACTGTCTCATGTGGGTCACTGCCGACCTGGTCTCC
TTCACCCTCATCGTGGGCATCTTCGTGCTCCAGAAGTGGCGCCTGGGTGGCATACGGAGCTACAACCCTGAGCAGATCATGCTGAGTGCT
GCGGTGCGCCGGACCAGCCGGGACGTCAGCATCATGAAGGAGAAGCTTATTTTCTCAGAGATCAGCGATGGTGTAGAGGTCTCCGATGTG
CTCTCCGTATGTTCAGACAACAGTTATGACACATATGCCAACAGCACCGCCACCCCTGTGGGCCCCCGAGGGGGTGGCAGCCACACCAAG

>In-frame_FBXL20_ENST00000577399_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_1743nt
ATGGCTCCGAGCAGGGACCGCCTGCTGCACTTTGGGTTCAAGGCGACAATGTTCTCAAATAGTGATGAAGCTGTAATCAATAAAAAACTT
CCCAAAGAACTCCTGTTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTCTCCAGGGCCTGGAATGTTCTG
GCTCTGGATGGCAGTAACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGTCCTGGCACTATGTCACATTGCCGTGGGG
CAGCAGATGAACCTGCACTGGCTGCACAAGATCGGGCTGGTGGTCATCCTGGCTTCCACGGTGGTGGCCATGTCGGCCGTGGCCCAGCTG
TGGGAGGACGAGTGGGAGGTGCTGCTGATCTCCCTGCAGGGCACAGCGCCATTCCTGCATGTGGGGGCTGTGGCAGCAGTCACCATGCTC
TCCTGGATCGTGGCAGGACAGTTCGCCCGCGCAGAGCGGACCTCCTCCCAGGTGACCATTCTCTGTACCTTCTTCACCGTGGTGTTTGCC
CTCTACCTGGCCCCTCTCACCATCTCCTCTCCCTGCATCATGGAGAAGAAAGACCTCGGCCCCAAGCCTGCTCTCATTGGCCACCGCGGG
GCCCCCATGCTGGCTCCAGAGCACACGCTCATGTCCTTCCGGAAGGCCCTCGAGCAGAAGCTGTACGGGCTCCAGGCTGACATTACCATC
AGCCTGGACGGCGTGCCCTTCCTCATGCATGACACCACCCTGCGGCGCACCACCAACGTGGAGGAGGAGTTCCCGGAGCTGGCCCGCAGG
CCTGCCTCCATGCTTAACTGGACCACCCTGCAGAGACTCAACGCTGGCCAGTGGTTCCTGAAGACTGACCCCTTCTGGACAGCCAGCTCC
CTGTCACCCTCCGACCACAGAGAGGCCCAGAACCAGTCCATCTGCAGCCTGGCAGAGCTCCTGGAGCTGGCCAAGGGCAATGCCACACTG
CTGCTCAACCTGCGTGACCCGCCCCGGGAGCACCCCTACCGCAGCAGTTTTATCAACGTGACTCTGGAGGCCGTGCTGCACTCCGGCTTC
CCCCAGCACCAGGTCATGTGGCTGCCTAGCAGGCAGAGGCCCCTGGTGCGGAAGGTGGCTCCCGGCTTCCAACAGACATCAGGCTCCAAG
GAGGCAGTCGCCAGCCTGCGGAGAGGCCACATCCAGCGGCTGAACCTGCGCTACACTCAGGTGTCCCGCCAGGAGCTCAGGGACTACGCG
TCCTGGAACCTGAGTGTGAACCTCTACACAGTCAACGCACCGTGGCTCTTCTCCCTGCTGTGGTGTGCGGGGGTCCCATCCGTCACCTCT
GACAACTCCCACGCCCTGTCCCAGGTGCCTTCCCCCCTCTGGATCATGCCCCCGGACGAGTACTGTCTCATGTGGGTCACTGCCGACCTG
GTCTCCTTCACCCTCATCGTGGGCATCTTCGTGCTCCAGAAGTGGCGCCTGGGTGGCATACGGAGCTACAACCCTGAGCAGATCATGCTG
AGTGCTGCGGTGCGCCGGACCAGCCGGGACGTCAGCATCATGAAGGAGAAGCTTATTTTCTCAGAGATCAGCGATGGTGTAGAGGTCTCC
GATGTGCTCTCCGTATGTTCAGACAACAGTTATGACACATATGCCAACAGCACCGCCACCCCTGTGGGCCCCCGAGGGGGTGGCAGCCAC


* Fusion transcript sequences (Full-length transcript).
>In-frame_FBXL20_ENST00000583610_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_2858nt
GTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTG
GAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCC
GGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGA
ACGGAGTGACCAAGAGCAGGTTTGAGATGTTCTCAAATAGTGATGAAGCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTGTTACGGA
TATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTCTCCAGGGCCTGGAATGTTCTGGCTCTGGATGGCAGTAACTGGC
AGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGTCCTGGCACTATGTCACATTGCCGTGGGGCAGCAGATGAACCTGCACTGGC
TGCACAAGATCGGGCTGGTGGTCATCCTGGCTTCCACGGTGGTGGCCATGTCGGCCGTGGCCCAGCTGTGGGAGGACGAGTGGGAGGTGC
TGCTGATCTCCCTGCAGGGCACAGCGCCATTCCTGCATGTGGGGGCTGTGGCAGCAGTCACCATGCTCTCCTGGATCGTGGCAGGACAGT
TCGCCCGCGCAGAGCGGACCTCCTCCCAGGTGACCATTCTCTGTACCTTCTTCACCGTGGTGTTTGCCCTCTACCTGGCCCCTCTCACCA
TCTCCTCTCCCTGCATCATGGAGAAGAAAGACCTCGGCCCCAAGCCTGCTCTCATTGGCCACCGCGGGGCCCCCATGCTGGCTCCAGAGC
ACACGCTCATGTCCTTCCGGAAGGCCCTCGAGCAGAAGCTGTACGGGCTCCAGGCTGACATTACCATCAGCCTGGACGGCGTGCCCTTCC
TCATGCATGACACCACCCTGCGGCGCACCACCAACGTGGAGGAGGAGTTCCCGGAGCTGGCCCGCAGGCCTGCCTCCATGCTTAACTGGA
CCACCCTGCAGAGACTCAACGCTGGCCAGTGGTTCCTGAAGACTGACCCCTTCTGGACAGCCAGCTCCCTGTCACCCTCCGACCACAGAG
AGGCCCAGAACCAGTCCATCTGCAGCCTGGCAGAGCTCCTGGAGCTGGCCAAGGGCAATGCCACACTGCTGCTCAACCTGCGTGACCCGC
CCCGGGAGCACCCCTACCGCAGCAGTTTTATCAACGTGACTCTGGAGGCCGTGCTGCACTCCGGCTTCCCCCAGCACCAGGTCATGTGGC
TGCCTAGCAGGCAGAGGCCCCTGGTGCGGAAGGTGGCTCCCGGCTTCCAACAGACATCAGGCTCCAAGGAGGCAGTCGCCAGCCTGCGGA
GAGGCCACATCCAGCGGCTGAACCTGCGCTACACTCAGGTGTCCCGCCAGGAGCTCAGGGACTACGCGTCCTGGAACCTGAGTGTGAACC
TCTACACAGTCAACGCACCGTGGCTCTTCTCCCTGCTGTGGTGTGCGGGGGTCCCATCCGTCACCTCTGACAACTCCCACGCCCTGTCCC
AGGTGCCTTCCCCCCTCTGGATCATGCCCCCGGACGAGTACTGTCTCATGTGGGTCACTGCCGACCTGGTCTCCTTCACCCTCATCGTGG
GCATCTTCGTGCTCCAGAAGTGGCGCCTGGGTGGCATACGGAGCTACAACCCTGAGCAGATCATGCTGAGTGCTGCGGTGCGCCGGACCA
GCCGGGACGTCAGCATCATGAAGGAGAAGCTTATTTTCTCAGAGATCAGCGATGGTGTAGAGGTCTCCGATGTGCTCTCCGTATGTTCAG
ACAACAGTTATGACACATATGCCAACAGCACCGCCACCCCTGTGGGCCCCCGAGGGGGTGGCAGCCACACCAAGACCCTCATAGAGCGGA
GTGGGCGTTAGCTGAAGACATGTCTGTCCCACCTGTACCTGACACAGAAGCTGGGGAGCCTAGGAGAGCTGGTGGAAGTGTGTCTGAACT
CGGAGTGCTCTGGGAGCGGGCTCCACAGCCTCCTTGTGGGCTCCAGCCCCTTGTCAGCCGCAGCCTCTCTTGAGGGGGACTCCCTGTCTC
CTGAGGCCCAGCTGGGCCAGGACTCCATCCTTTCAGATGCCCCTGCAGGCCTGGGGCTCCTTCTGGGAAGTATGGGGCCTAGGGCTTGGT
CCCCCTCTTCTGAGGCCCTCTCCTGTATCCCGACCTGGAAGCTTTGATGGGTCATGGGCCATGCCATACCCCCTGTGGCAATGGAGTGTG
TGGATGCTCACCTGTGCCATCTGTCCTCCTGTCTGTGCCAGGAGGCACCTGAGTTCTCTGCTGTTATCCTGCCCCAAGGGCCTGGGCCGA
GCCTCTACCTGAAGCAACTCTGCTCTTCCTGTCAGTCTCAAAGCACAAGGAGGTTCAGCCCAGGAGGAAGCCAGCTGCAATGTGGAGACA
CGTCCTCCTCCCCAACCCACCTCATGCCACCGCCAACCCCCTGCCCCAGGAGCGGGCCTGAGCCACGTCCTCTAGGAGCAGCTGGAGATG
GCCAAAAGAGTGAGCTCAGGACTACTGGATCCCATGCCCAGGTGTCCAGCAGACCTCAAGGCAGAAGGGTCACCTAACCCAGGAGTCCAC
AGACTGATGTGACCTCAGGTTCCCACATCAGTGGCCACAGGGCAGGGCCCACCTGGTAGAAGTGTTCTGGATATGGCCAGGGTGGGTGTG

>In-frame_FBXL20_ENST00000394294_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_2825nt
GAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTC
CCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCC
GCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGATGTTCT
CAAATAGTGATGAAGCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTGTTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCC
GCTGTGCTCAGGTCTCCAGGGCCTGGAATGTTCTGGCTCTGGATGGCAGTAACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATA
TTGAGGTCCTGGCACTATGTCACATTGCCGTGGGGCAGCAGATGAACCTGCACTGGCTGCACAAGATCGGGCTGGTGGTCATCCTGGCTT
CCACGGTGGTGGCCATGTCGGCCGTGGCCCAGCTGTGGGAGGACGAGTGGGAGGTGCTGCTGATCTCCCTGCAGGGCACAGCGCCATTCC
TGCATGTGGGGGCTGTGGCAGCAGTCACCATGCTCTCCTGGATCGTGGCAGGACAGTTCGCCCGCGCAGAGCGGACCTCCTCCCAGGTGA
CCATTCTCTGTACCTTCTTCACCGTGGTGTTTGCCCTCTACCTGGCCCCTCTCACCATCTCCTCTCCCTGCATCATGGAGAAGAAAGACC
TCGGCCCCAAGCCTGCTCTCATTGGCCACCGCGGGGCCCCCATGCTGGCTCCAGAGCACACGCTCATGTCCTTCCGGAAGGCCCTCGAGC
AGAAGCTGTACGGGCTCCAGGCTGACATTACCATCAGCCTGGACGGCGTGCCCTTCCTCATGCATGACACCACCCTGCGGCGCACCACCA
ACGTGGAGGAGGAGTTCCCGGAGCTGGCCCGCAGGCCTGCCTCCATGCTTAACTGGACCACCCTGCAGAGACTCAACGCTGGCCAGTGGT
TCCTGAAGACTGACCCCTTCTGGACAGCCAGCTCCCTGTCACCCTCCGACCACAGAGAGGCCCAGAACCAGTCCATCTGCAGCCTGGCAG
AGCTCCTGGAGCTGGCCAAGGGCAATGCCACACTGCTGCTCAACCTGCGTGACCCGCCCCGGGAGCACCCCTACCGCAGCAGTTTTATCA
ACGTGACTCTGGAGGCCGTGCTGCACTCCGGCTTCCCCCAGCACCAGGTCATGTGGCTGCCTAGCAGGCAGAGGCCCCTGGTGCGGAAGG
TGGCTCCCGGCTTCCAACAGACATCAGGCTCCAAGGAGGCAGTCGCCAGCCTGCGGAGAGGCCACATCCAGCGGCTGAACCTGCGCTACA
CTCAGGTGTCCCGCCAGGAGCTCAGGGACTACGCGTCCTGGAACCTGAGTGTGAACCTCTACACAGTCAACGCACCGTGGCTCTTCTCCC
TGCTGTGGTGTGCGGGGGTCCCATCCGTCACCTCTGACAACTCCCACGCCCTGTCCCAGGTGCCTTCCCCCCTCTGGATCATGCCCCCGG
ACGAGTACTGTCTCATGTGGGTCACTGCCGACCTGGTCTCCTTCACCCTCATCGTGGGCATCTTCGTGCTCCAGAAGTGGCGCCTGGGTG
GCATACGGAGCTACAACCCTGAGCAGATCATGCTGAGTGCTGCGGTGCGCCGGACCAGCCGGGACGTCAGCATCATGAAGGAGAAGCTTA
TTTTCTCAGAGATCAGCGATGGTGTAGAGGTCTCCGATGTGCTCTCCGTATGTTCAGACAACAGTTATGACACATATGCCAACAGCACCG
CCACCCCTGTGGGCCCCCGAGGGGGTGGCAGCCACACCAAGACCCTCATAGAGCGGAGTGGGCGTTAGCTGAAGACATGTCTGTCCCACC
TGTACCTGACACAGAAGCTGGGGAGCCTAGGAGAGCTGGTGGAAGTGTGTCTGAACTCGGAGTGCTCTGGGAGCGGGCTCCACAGCCTCC
TTGTGGGCTCCAGCCCCTTGTCAGCCGCAGCCTCTCTTGAGGGGGACTCCCTGTCTCCTGAGGCCCAGCTGGGCCAGGACTCCATCCTTT
CAGATGCCCCTGCAGGCCTGGGGCTCCTTCTGGGAAGTATGGGGCCTAGGGCTTGGTCCCCCTCTTCTGAGGCCCTCTCCTGTATCCCGA
CCTGGAAGCTTTGATGGGTCATGGGCCATGCCATACCCCCTGTGGCAATGGAGTGTGTGGATGCTCACCTGTGCCATCTGTCCTCCTGTC
TGTGCCAGGAGGCACCTGAGTTCTCTGCTGTTATCCTGCCCCAAGGGCCTGGGCCGAGCCTCTACCTGAAGCAACTCTGCTCTTCCTGTC
AGTCTCAAAGCACAAGGAGGTTCAGCCCAGGAGGAAGCCAGCTGCAATGTGGAGACACGTCCTCCTCCCCAACCCACCTCATGCCACCGC
CAACCCCCTGCCCCAGGAGCGGGCCTGAGCCACGTCCTCTAGGAGCAGCTGGAGATGGCCAAAAGAGTGAGCTCAGGACTACTGGATCCC
ATGCCCAGGTGTCCAGCAGACCTCAAGGCAGAAGGGTCACCTAACCCAGGAGTCCACAGACTGATGTGACCTCAGGTTCCCACATCAGTG
GCCACAGGGCAGGGCCCACCTGGTAGAAGTGTTCTGGATATGGCCAGGGTGGGTGTGTGGCTAAGTGGGCCTGAACAGAGGGAACCTAGG

>In-frame_FBXL20_ENST00000264658_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_2865nt
GGGGAGTGTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGA
GGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGG
AACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGG
GACGTGAACGGAGTGACCAAGAGCAGGTTTGAGATGTTCTCAAATAGTGATGAAGCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTG
TTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGCTGTGCTCAGGTCTCCAGGGCCTGGAATGTTCTGGCTCTGGATGGCAGT
AACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATTGAGGTCCTGGCACTATGTCACATTGCCGTGGGGCAGCAGATGAACCTG
CACTGGCTGCACAAGATCGGGCTGGTGGTCATCCTGGCTTCCACGGTGGTGGCCATGTCGGCCGTGGCCCAGCTGTGGGAGGACGAGTGG
GAGGTGCTGCTGATCTCCCTGCAGGGCACAGCGCCATTCCTGCATGTGGGGGCTGTGGCAGCAGTCACCATGCTCTCCTGGATCGTGGCA
GGACAGTTCGCCCGCGCAGAGCGGACCTCCTCCCAGGTGACCATTCTCTGTACCTTCTTCACCGTGGTGTTTGCCCTCTACCTGGCCCCT
CTCACCATCTCCTCTCCCTGCATCATGGAGAAGAAAGACCTCGGCCCCAAGCCTGCTCTCATTGGCCACCGCGGGGCCCCCATGCTGGCT
CCAGAGCACACGCTCATGTCCTTCCGGAAGGCCCTCGAGCAGAAGCTGTACGGGCTCCAGGCTGACATTACCATCAGCCTGGACGGCGTG
CCCTTCCTCATGCATGACACCACCCTGCGGCGCACCACCAACGTGGAGGAGGAGTTCCCGGAGCTGGCCCGCAGGCCTGCCTCCATGCTT
AACTGGACCACCCTGCAGAGACTCAACGCTGGCCAGTGGTTCCTGAAGACTGACCCCTTCTGGACAGCCAGCTCCCTGTCACCCTCCGAC
CACAGAGAGGCCCAGAACCAGTCCATCTGCAGCCTGGCAGAGCTCCTGGAGCTGGCCAAGGGCAATGCCACACTGCTGCTCAACCTGCGT
GACCCGCCCCGGGAGCACCCCTACCGCAGCAGTTTTATCAACGTGACTCTGGAGGCCGTGCTGCACTCCGGCTTCCCCCAGCACCAGGTC
ATGTGGCTGCCTAGCAGGCAGAGGCCCCTGGTGCGGAAGGTGGCTCCCGGCTTCCAACAGACATCAGGCTCCAAGGAGGCAGTCGCCAGC
CTGCGGAGAGGCCACATCCAGCGGCTGAACCTGCGCTACACTCAGGTGTCCCGCCAGGAGCTCAGGGACTACGCGTCCTGGAACCTGAGT
GTGAACCTCTACACAGTCAACGCACCGTGGCTCTTCTCCCTGCTGTGGTGTGCGGGGGTCCCATCCGTCACCTCTGACAACTCCCACGCC
CTGTCCCAGGTGCCTTCCCCCCTCTGGATCATGCCCCCGGACGAGTACTGTCTCATGTGGGTCACTGCCGACCTGGTCTCCTTCACCCTC
ATCGTGGGCATCTTCGTGCTCCAGAAGTGGCGCCTGGGTGGCATACGGAGCTACAACCCTGAGCAGATCATGCTGAGTGCTGCGGTGCGC
CGGACCAGCCGGGACGTCAGCATCATGAAGGAGAAGCTTATTTTCTCAGAGATCAGCGATGGTGTAGAGGTCTCCGATGTGCTCTCCGTA
TGTTCAGACAACAGTTATGACACATATGCCAACAGCACCGCCACCCCTGTGGGCCCCCGAGGGGGTGGCAGCCACACCAAGACCCTCATA
GAGCGGAGTGGGCGTTAGCTGAAGACATGTCTGTCCCACCTGTACCTGACACAGAAGCTGGGGAGCCTAGGAGAGCTGGTGGAAGTGTGT
CTGAACTCGGAGTGCTCTGGGAGCGGGCTCCACAGCCTCCTTGTGGGCTCCAGCCCCTTGTCAGCCGCAGCCTCTCTTGAGGGGGACTCC
CTGTCTCCTGAGGCCCAGCTGGGCCAGGACTCCATCCTTTCAGATGCCCCTGCAGGCCTGGGGCTCCTTCTGGGAAGTATGGGGCCTAGG
GCTTGGTCCCCCTCTTCTGAGGCCCTCTCCTGTATCCCGACCTGGAAGCTTTGATGGGTCATGGGCCATGCCATACCCCCTGTGGCAATG
GAGTGTGTGGATGCTCACCTGTGCCATCTGTCCTCCTGTCTGTGCCAGGAGGCACCTGAGTTCTCTGCTGTTATCCTGCCCCAAGGGCCT
GGGCCGAGCCTCTACCTGAAGCAACTCTGCTCTTCCTGTCAGTCTCAAAGCACAAGGAGGTTCAGCCCAGGAGGAAGCCAGCTGCAATGT
GGAGACACGTCCTCCTCCCCAACCCACCTCATGCCACCGCCAACCCCCTGCCCCAGGAGCGGGCCTGAGCCACGTCCTCTAGGAGCAGCT
GGAGATGGCCAAAAGAGTGAGCTCAGGACTACTGGATCCCATGCCCAGGTGTCCAGCAGACCTCAAGGCAGAAGGGTCACCTAACCCAGG
AGTCCACAGACTGATGTGACCTCAGGTTCCCACATCAGTGGCCACAGGGCAGGGCCCACCTGGTAGAAGTGTTCTGGATATGGCCAGGGT

>In-frame_FBXL20_ENST00000577399_chr17_37457254_-_GDPD5_ENST00000336898_chr11_75167861_-_2913nt
GCCAAAGGAAGGGTTGCCCGGCTCCAGCCCTGCACCCCCGACCCCCGGCCTCAGGTGCAGCTCCGCAGCCATCCCCGGACCAGGGCGGGC
ACTTGGCCTGTTGCTCAGCGCAACCACCCTCGCCCTCCCGAGCCATGCACAGGGAGACAAGCGTCCGGCCCCGGCCCCCCAGGCCTCCCT
GCAGCACCCCGTAATGTAATGCACTGGGGCGGGGGAGGCGGGGGAGGCGGCGGCGGCGGCAACCGCGGAGGCGCGGCGGCAGCCGCACTG
CCCCAATCTAGACACATCCAGAAGAGGAGGAAAATGGCTCCGAGCAGGGACCGCCTGCTGCACTTTGGGTTCAAGGCGACAATGTTCTCA
AATAGTGATGAAGCTGTAATCAATAAAAAACTTCCCAAAGAACTCCTGTTACGGATATTTTCTTTTCTAGATGTTGTTACCCTGTGCCGC
TGTGCTCAGGTCTCCAGGGCCTGGAATGTTCTGGCTCTGGATGGCAGTAACTGGCAGCGAATTGACCTATTTGATTTCCAGAGGGATATT
GAGGTCCTGGCACTATGTCACATTGCCGTGGGGCAGCAGATGAACCTGCACTGGCTGCACAAGATCGGGCTGGTGGTCATCCTGGCTTCC
ACGGTGGTGGCCATGTCGGCCGTGGCCCAGCTGTGGGAGGACGAGTGGGAGGTGCTGCTGATCTCCCTGCAGGGCACAGCGCCATTCCTG
CATGTGGGGGCTGTGGCAGCAGTCACCATGCTCTCCTGGATCGTGGCAGGACAGTTCGCCCGCGCAGAGCGGACCTCCTCCCAGGTGACC
ATTCTCTGTACCTTCTTCACCGTGGTGTTTGCCCTCTACCTGGCCCCTCTCACCATCTCCTCTCCCTGCATCATGGAGAAGAAAGACCTC
GGCCCCAAGCCTGCTCTCATTGGCCACCGCGGGGCCCCCATGCTGGCTCCAGAGCACACGCTCATGTCCTTCCGGAAGGCCCTCGAGCAG
AAGCTGTACGGGCTCCAGGCTGACATTACCATCAGCCTGGACGGCGTGCCCTTCCTCATGCATGACACCACCCTGCGGCGCACCACCAAC
GTGGAGGAGGAGTTCCCGGAGCTGGCCCGCAGGCCTGCCTCCATGCTTAACTGGACCACCCTGCAGAGACTCAACGCTGGCCAGTGGTTC
CTGAAGACTGACCCCTTCTGGACAGCCAGCTCCCTGTCACCCTCCGACCACAGAGAGGCCCAGAACCAGTCCATCTGCAGCCTGGCAGAG
CTCCTGGAGCTGGCCAAGGGCAATGCCACACTGCTGCTCAACCTGCGTGACCCGCCCCGGGAGCACCCCTACCGCAGCAGTTTTATCAAC
GTGACTCTGGAGGCCGTGCTGCACTCCGGCTTCCCCCAGCACCAGGTCATGTGGCTGCCTAGCAGGCAGAGGCCCCTGGTGCGGAAGGTG
GCTCCCGGCTTCCAACAGACATCAGGCTCCAAGGAGGCAGTCGCCAGCCTGCGGAGAGGCCACATCCAGCGGCTGAACCTGCGCTACACT
CAGGTGTCCCGCCAGGAGCTCAGGGACTACGCGTCCTGGAACCTGAGTGTGAACCTCTACACAGTCAACGCACCGTGGCTCTTCTCCCTG
CTGTGGTGTGCGGGGGTCCCATCCGTCACCTCTGACAACTCCCACGCCCTGTCCCAGGTGCCTTCCCCCCTCTGGATCATGCCCCCGGAC
GAGTACTGTCTCATGTGGGTCACTGCCGACCTGGTCTCCTTCACCCTCATCGTGGGCATCTTCGTGCTCCAGAAGTGGCGCCTGGGTGGC
ATACGGAGCTACAACCCTGAGCAGATCATGCTGAGTGCTGCGGTGCGCCGGACCAGCCGGGACGTCAGCATCATGAAGGAGAAGCTTATT
TTCTCAGAGATCAGCGATGGTGTAGAGGTCTCCGATGTGCTCTCCGTATGTTCAGACAACAGTTATGACACATATGCCAACAGCACCGCC
ACCCCTGTGGGCCCCCGAGGGGGTGGCAGCCACACCAAGACCCTCATAGAGCGGAGTGGGCGTTAGCTGAAGACATGTCTGTCCCACCTG
TACCTGACACAGAAGCTGGGGAGCCTAGGAGAGCTGGTGGAAGTGTGTCTGAACTCGGAGTGCTCTGGGAGCGGGCTCCACAGCCTCCTT
GTGGGCTCCAGCCCCTTGTCAGCCGCAGCCTCTCTTGAGGGGGACTCCCTGTCTCCTGAGGCCCAGCTGGGCCAGGACTCCATCCTTTCA
GATGCCCCTGCAGGCCTGGGGCTCCTTCTGGGAAGTATGGGGCCTAGGGCTTGGTCCCCCTCTTCTGAGGCCCTCTCCTGTATCCCGACC
TGGAAGCTTTGATGGGTCATGGGCCATGCCATACCCCCTGTGGCAATGGAGTGTGTGGATGCTCACCTGTGCCATCTGTCCTCCTGTCTG
TGCCAGGAGGCACCTGAGTTCTCTGCTGTTATCCTGCCCCAAGGGCCTGGGCCGAGCCTCTACCTGAAGCAACTCTGCTCTTCCTGTCAG
TCTCAAAGCACAAGGAGGTTCAGCCCAGGAGGAAGCCAGCTGCAATGTGGAGACACGTCCTCCTCCCCAACCCACCTCATGCCACCGCCA
ACCCCCTGCCCCAGGAGCGGGCCTGAGCCACGTCCTCTAGGAGCAGCTGGAGATGGCCAAAAGAGTGAGCTCAGGACTACTGGATCCCAT
GCCCAGGTGTCCAGCAGACCTCAAGGCAGAAGGGTCACCTAACCCAGGAGTCCACAGACTGATGTGACCTCAGGTTCCCACATCAGTGGC
CACAGGGCAGGGCCCACCTGGTAGAAGTGTTCTGGATATGGCCAGGGTGGGTGTGTGGCTAAGTGGGCCTGAACAGAGGGAACCTAGGGC


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FusionGenePPI for FBXL20_GDPD5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
FBXL20CUL1, KRAS, YPEL3, PVR, YPEL1, RABGGTBGDPD5PLSCR1, PEX5, SIAH1, TRIP6, KRTAP26-1, LYPD3, ROBO1, GPD2, PIGQ, SELT, TMEM55A, IGSF8, LEMD2, SCAMP4, ZMPSTE24, VTI1B, NDUFS4, KCNJ11, ZDHHC9, TYW1, C1orf43, STX7, NDUFA12, STX8, CHSY3, EDA, RETSAT, ADCY6, NDUFS6, ZDHHC18, GPR89B, TEX264, TMEM205, GPRC5C, MARC1, GOLIM4, THEM6, SGPP1, FAM213A, NDC1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for FBXL20_GDPD5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for FBXL20_GDPD5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource