	FusionGeneSummary
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Fusion gene ID: 13015

FusionGeneSummary for FBLN1_FBLN1

Fusion gene summary

Fusion gene information	Fusion gene name: FBLN1_FBLN1
	Fusion gene ID: 13015
		Hgene	Tgene
	Gene symbol	FBLN1	FBLN1
	Gene ID	2192	2192
	Gene name	fibulin 1	fibulin 1
	Synonyms	FBLN\|FIBL1	FBLN\|FIBL1
	Cytomap	22q13.31	22q13.31
	Type of gene	protein-coding	protein-coding
	Description	fibulin-1	fibulin-1
	Modification date	20180522	20180522
	UniProtAcc	P23142	P23142
	Ensembl transtripts involved in fusion gene	ENST00000348697, ENST00000402984, ENST00000262722, ENST00000327858, ENST00000442170, ENST00000340923, ENST00000476366,	ENST00000348697, ENST00000402984, ENST00000262722, ENST00000327858, ENST00000442170, ENST00000340923, ENST00000476366,
Fusion gene scores	* DoF score	8 X 9 X 5=360	12 X 11 X 7=924
	# samples	10	13
	** MAII score	log2(10/360*10)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(13/924*10)=-2.8293812283876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: FBLN1 [Title/Abstract] AND FBLN1 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	FBLN1	GO:0001933	negative regulation of protein phosphorylation	11792823
Hgene	FBLN1	GO:0007162	negative regulation of cell adhesion	11792823
Hgene	FBLN1	GO:0007229	integrin-mediated signaling pathway	11792823
Hgene	FBLN1	GO:0070373	negative regulation of ERK1 and ERK2 cascade	11792823
Hgene	FBLN1	GO:0072378	blood coagulation, fibrin clot formation	7642629
Hgene	FBLN1	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	11792823
Hgene	FBLN1	GO:2000146	negative regulation of cell motility	11792823
Hgene	FBLN1	GO:2000647	negative regulation of stem cell proliferation	11238726
Tgene	FBLN1	GO:0001933	negative regulation of protein phosphorylation	11792823
Tgene	FBLN1	GO:0007162	negative regulation of cell adhesion	11792823
Tgene	FBLN1	GO:0007229	integrin-mediated signaling pathway	11792823
Tgene	FBLN1	GO:0070373	negative regulation of ERK1 and ERK2 cascade	11792823
Tgene	FBLN1	GO:0072378	blood coagulation, fibrin clot formation	7642629
Tgene	FBLN1	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	11792823
Tgene	FBLN1	GO:2000146	negative regulation of cell motility	11792823
Tgene	FBLN1	GO:2000647	negative regulation of stem cell proliferation	11238726

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS3.1			BG827383	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
ChiTaRS3.1			BE931220	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
ChiTaRS3.1			BE929893	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000348697	ENST00000348697	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000348697	ENST00000402984	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000348697	ENST00000262722	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000348697	ENST00000327858	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000348697	ENST00000442170	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000348697	ENST00000340923	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
5CDS-intron	ENST00000348697	ENST00000476366	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000402984	ENST00000348697	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000402984	ENST00000402984	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000402984	ENST00000262722	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000402984	ENST00000327858	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000402984	ENST00000442170	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000402984	ENST00000340923	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
5CDS-intron	ENST00000402984	ENST00000476366	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000262722	ENST00000348697	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000262722	ENST00000402984	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000262722	ENST00000262722	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000262722	ENST00000327858	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000262722	ENST00000442170	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000262722	ENST00000340923	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
5CDS-intron	ENST00000262722	ENST00000476366	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000327858	ENST00000348697	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000327858	ENST00000402984	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000327858	ENST00000262722	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000327858	ENST00000327858	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000327858	ENST00000442170	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000327858	ENST00000340923	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
5CDS-intron	ENST00000327858	ENST00000476366	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000442170	ENST00000348697	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000442170	ENST00000402984	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000442170	ENST00000262722	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000442170	ENST00000327858	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000442170	ENST00000442170	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000442170	ENST00000340923	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
5CDS-intron	ENST00000442170	ENST00000476366	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000340923	ENST00000348697	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000340923	ENST00000402984	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000340923	ENST00000262722	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000340923	ENST00000327858	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000340923	ENST00000442170	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000340923	ENST00000340923	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
5CDS-intron	ENST00000340923	ENST00000476366	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
intron-3CDS	ENST00000476366	ENST00000348697	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
intron-3CDS	ENST00000476366	ENST00000402984	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
intron-3CDS	ENST00000476366	ENST00000262722	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
intron-3CDS	ENST00000476366	ENST00000327858	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
intron-3CDS	ENST00000476366	ENST00000442170	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
intron-3CDS	ENST00000476366	ENST00000340923	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
intron-intron	ENST00000476366	ENST00000476366	FBLN1	chr22	45931100	-	FBLN1	chr22	45931135	+
In-frame	ENST00000348697	ENST00000348697	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000348697	ENST00000402984	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000348697	ENST00000262722	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000348697	ENST00000327858	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000348697	ENST00000442170	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000348697	ENST00000340923	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
5CDS-intron	ENST00000348697	ENST00000476366	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000402984	ENST00000348697	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000402984	ENST00000402984	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000402984	ENST00000262722	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000402984	ENST00000327858	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000402984	ENST00000442170	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000402984	ENST00000340923	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
5CDS-intron	ENST00000402984	ENST00000476366	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000262722	ENST00000348697	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000262722	ENST00000402984	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000262722	ENST00000262722	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000262722	ENST00000327858	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000262722	ENST00000442170	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000262722	ENST00000340923	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
5CDS-intron	ENST00000262722	ENST00000476366	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000327858	ENST00000348697	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000327858	ENST00000402984	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000327858	ENST00000262722	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000327858	ENST00000327858	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000327858	ENST00000442170	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000327858	ENST00000340923	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
5CDS-intron	ENST00000327858	ENST00000476366	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000442170	ENST00000348697	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000442170	ENST00000402984	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000442170	ENST00000262722	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000442170	ENST00000327858	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000442170	ENST00000442170	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000442170	ENST00000340923	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
5CDS-intron	ENST00000442170	ENST00000476366	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000340923	ENST00000348697	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000340923	ENST00000402984	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000340923	ENST00000262722	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000340923	ENST00000327858	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000340923	ENST00000442170	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
In-frame	ENST00000340923	ENST00000340923	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
5CDS-intron	ENST00000340923	ENST00000476366	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
intron-3CDS	ENST00000476366	ENST00000348697	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
intron-3CDS	ENST00000476366	ENST00000402984	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
intron-3CDS	ENST00000476366	ENST00000262722	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
intron-3CDS	ENST00000476366	ENST00000327858	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
intron-3CDS	ENST00000476366	ENST00000442170	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
intron-3CDS	ENST00000476366	ENST00000340923	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
intron-intron	ENST00000476366	ENST00000476366	FBLN1	chr22	45929727	-	FBLN1	chr22	45929014	+
5CDS-intron	ENST00000348697	ENST00000348697	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000348697	ENST00000402984	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000348697	ENST00000262722	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000348697	ENST00000327858	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000348697	ENST00000442170	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000348697	ENST00000340923	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000348697	ENST00000476366	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000402984	ENST00000348697	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000402984	ENST00000402984	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000402984	ENST00000262722	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000402984	ENST00000327858	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000402984	ENST00000442170	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000402984	ENST00000340923	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000402984	ENST00000476366	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000262722	ENST00000348697	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000262722	ENST00000402984	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000262722	ENST00000262722	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000262722	ENST00000327858	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000262722	ENST00000442170	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000262722	ENST00000340923	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000262722	ENST00000476366	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000327858	ENST00000348697	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000327858	ENST00000402984	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000327858	ENST00000262722	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000327858	ENST00000327858	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000327858	ENST00000442170	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000327858	ENST00000340923	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
5CDS-intron	ENST00000327858	ENST00000476366	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000442170	ENST00000348697	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000442170	ENST00000402984	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000442170	ENST00000262722	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000442170	ENST00000327858	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000442170	ENST00000442170	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000442170	ENST00000340923	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000442170	ENST00000476366	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000340923	ENST00000348697	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000340923	ENST00000402984	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000340923	ENST00000262722	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000340923	ENST00000327858	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000340923	ENST00000442170	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000340923	ENST00000340923	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000340923	ENST00000476366	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000476366	ENST00000348697	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000476366	ENST00000402984	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000476366	ENST00000262722	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000476366	ENST00000327858	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000476366	ENST00000442170	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000476366	ENST00000340923	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+
intron-intron	ENST00000476366	ENST00000476366	FBLN1	chr22	45996311	-	FBLN1	chr22	45970426	+

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FusionProtFeatures for FBLN1_FBLN1

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
FBLN1 P23142	FBLN1 P23142

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
.

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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FusionGeneSequence for FBLN1_FBLN1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for FBLN1_FBLN1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page
.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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RelatedDrugs for FBLN1_FBLN1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for FBLN1_FBLN1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	FBLN1	C0014175	Endometriosis	1	CTD_human
Hgene	FBLN1	C0033578	Prostatic Neoplasms	1	CTD_human
Tgene	FBLN1	C0014175	Endometriosis	1	CTD_human
Tgene	FBLN1	C0033578	Prostatic Neoplasms	1	CTD_human

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Fusion gene ID: 13015

FusionGeneSummary for FBLN1_FBLN1

FusionProtFeatures for FBLN1_FBLN1

FusionGeneSequence for FBLN1_FBLN1

FusionGenePPI for FBLN1_FBLN1

RelatedDrugs for FBLN1_FBLN1

RelatedDiseases for FBLN1_FBLN1