|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 12747 |
FusionGeneSummary for FAM214A_CCDC102B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FAM214A_CCDC102B | Fusion gene ID: 12747 | Hgene | Tgene | Gene symbol | FAM214A | CCDC102B | Gene ID | 56204 | 79839 |
| Gene name | family with sequence similarity 214 member A | coiled-coil domain containing 102B | |
| Synonyms | KIAA1370 | ACY1L|AN|C18orf14|HsT1731 | |
| Cytomap | 15q21.2-q21.3 | 18q22.1-q22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein FAM214A | coiled-coil domain-containing protein 102B | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q32MH5 | Q68D86 | |
| Ensembl transtripts involved in fusion gene | ENST00000261844, ENST00000562351, ENST00000546305, | ENST00000319445, ENST00000360242, ENST00000584156, ENST00000358653, ENST00000577772, | |
| Fusion gene scores | * DoF score | 4 X 4 X 3=48 | 3 X 3 X 3=27 |
| # samples | 5 | 3 | |
| ** MAII score | log2(5/48*10)=0.0588936890535686 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: FAM214A [Title/Abstract] AND CCDC102B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-SG-A6Z4-01A | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000261844 | ENST00000319445 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| In-frame | ENST00000261844 | ENST00000360242 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| 5CDS-intron | ENST00000261844 | ENST00000584156 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| 5CDS-intron | ENST00000261844 | ENST00000358653 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| 5CDS-intron | ENST00000261844 | ENST00000577772 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| intron-3CDS | ENST00000562351 | ENST00000319445 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| intron-3CDS | ENST00000562351 | ENST00000360242 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| intron-intron | ENST00000562351 | ENST00000584156 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| intron-intron | ENST00000562351 | ENST00000358653 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| intron-intron | ENST00000562351 | ENST00000577772 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| Frame-shift | ENST00000546305 | ENST00000319445 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| Frame-shift | ENST00000546305 | ENST00000360242 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| 5CDS-intron | ENST00000546305 | ENST00000584156 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| 5CDS-intron | ENST00000546305 | ENST00000358653 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
| 5CDS-intron | ENST00000546305 | ENST00000577772 | FAM214A | chr15 | 52885775 | - | CCDC102B | chr18 | 66721267 | + |
Top |
FusionProtFeatures for FAM214A_CCDC102B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FAM214A | CCDC102B |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >CCDC102B | chr15:52885775 | chr18:66721267 | ENST00000584156 | + | 0 | 6 | 268_337 | 0 | 484 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >CCDC102B | chr15:52885775 | chr18:66721267 | ENST00000584156 | + | 0 | 6 | 363_513 | 0 | 484 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >CCDC102B | chr15:52885775 | chr18:66721267 | ENST00000584156 | + | 0 | 6 | 72_142 | 0 | 484 | Coiled coil | Ontology_term=ECO:0000255 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | CCDC102B | chr15:52885775 | chr18:66721267 | ENST00000319445 | + | 6 | 8 | 268_337 | 478 | 514 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CCDC102B | chr15:52885775 | chr18:66721267 | ENST00000319445 | + | 6 | 8 | 363_513 | 478 | 514 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CCDC102B | chr15:52885775 | chr18:66721267 | ENST00000319445 | + | 6 | 8 | 72_142 | 478 | 514 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CCDC102B | chr15:52885775 | chr18:66721267 | ENST00000360242 | + | 6 | 8 | 268_337 | 478 | 514 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CCDC102B | chr15:52885775 | chr18:66721267 | ENST00000360242 | + | 6 | 8 | 363_513 | 478 | 514 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | CCDC102B | chr15:52885775 | chr18:66721267 | ENST00000360242 | + | 6 | 8 | 72_142 | 478 | 514 | Coiled coil | Ontology_term=ECO:0000255 |
Top |
FusionGeneSequence for FAM214A_CCDC102B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FAM214A_ENST00000261844_chr15_52885775_-_CCDC102B_ENST00000319445_chr18_66721267_+_972aa MKPDRDTLDEYFEYDAEEFLVSLALLITEGRTPECSVKGRTESFHCPPAQSCYPVTTKHECSDKLAQCRQARRTRSEVTLLWKNNLPIMV EMMLLPDCCYSDDGPTTEGIDLNDPAIKQDALLLERWILEPVPRQNGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISA ADVDLQWNFSQTPIEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNIGLYEKRIQQHKLKTHQHHNPNEAEQCGTNSSQRLCSK QTWTMAPESVLHAKSGPSPEYTAAVKNIKLYPGTGSKSDHGTSQANILGFSGIGDIKSQETSVRTLKSFSMVDSSISNRQSFWQSAGETN PLIGSLIQERQEIIARIAQHLIHCDPSTSHVSGRPFNTQESSSLHSKLFRVSQENENVGKGKEAFSMTFGSPEFSSPEDTNEGKIRLKPE TPRSETCISNDFYSHMPVGETNPLIGSLLQERQDVIARIAQHLEHIDPTASHIPRQSFNMHDSSSVASKVFRSSYEDKNLLKKNKDESSV SISHTKCSLLGDISDGKNLVPNKCFTSFKNNSKEKCSLKHQTRNQCQNNPSEIIQSTYQETQNKSSSLSTSSILSQHKENNLDLTSRFKE QEMSNGIDKQYSNCTTIDKQICTNKYKEKIINENYNPKFFGNLQSDDSKKNDSKIKVTVLEMSEYLNKYESMSSNKDSKRPKTCEQNTQL NSIENYLNKDNEGFKCKKSDQLKNEQDKQEDPTNEKSQNYSQRRSIKDCLSTCEQPKNTEVLRTTLKHSNVWRKHNFHSLDGTSTRAFHP QTGLPLLSSPVPQRKTQSGCFDLDSSLLHLKSFSSRSPRPCLNIEDDPDIHEKPFLSSSAPPITSLSLLGNFEESVLNYRFDPLGIVDGF >In-frame_FAM214A_ENST00000261844_chr15_52885775_-_CCDC102B_ENST00000360242_chr18_66721267_+_972aa MKPDRDTLDEYFEYDAEEFLVSLALLITEGRTPECSVKGRTESFHCPPAQSCYPVTTKHECSDKLAQCRQARRTRSEVTLLWKNNLPIMV EMMLLPDCCYSDDGPTTEGIDLNDPAIKQDALLLERWILEPVPRQNGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAIPRNILYRISA ADVDLQWNFSQTPIEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNIGLYEKRIQQHKLKTHQHHNPNEAEQCGTNSSQRLCSK QTWTMAPESVLHAKSGPSPEYTAAVKNIKLYPGTGSKSDHGTSQANILGFSGIGDIKSQETSVRTLKSFSMVDSSISNRQSFWQSAGETN PLIGSLIQERQEIIARIAQHLIHCDPSTSHVSGRPFNTQESSSLHSKLFRVSQENENVGKGKEAFSMTFGSPEFSSPEDTNEGKIRLKPE TPRSETCISNDFYSHMPVGETNPLIGSLLQERQDVIARIAQHLEHIDPTASHIPRQSFNMHDSSSVASKVFRSSYEDKNLLKKNKDESSV SISHTKCSLLGDISDGKNLVPNKCFTSFKNNSKEKCSLKHQTRNQCQNNPSEIIQSTYQETQNKSSSLSTSSILSQHKENNLDLTSRFKE QEMSNGIDKQYSNCTTIDKQICTNKYKEKIINENYNPKFFGNLQSDDSKKNDSKIKVTVLEMSEYLNKYESMSSNKDSKRPKTCEQNTQL NSIENYLNKDNEGFKCKKSDQLKNEQDKQEDPTNEKSQNYSQRRSIKDCLSTCEQPKNTEVLRTTLKHSNVWRKHNFHSLDGTSTRAFHP QTGLPLLSSPVPQRKTQSGCFDLDSSLLHLKSFSSRSPRPCLNIEDDPDIHEKPFLSSSAPPITSLSLLGNFEESVLNYRFDPLGIVDGF |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FAM214A_ENST00000261844_chr15_52885775_-_CCDC102B_ENST00000319445_chr18_66721267_+_2916nt ATGAAGCCAGACCGAGATACTCTGGATGAATATTTTGAATATGATGCAGAGGAGTTCTTGGTCTCTTTGGCCTTGCTGATAACAGAAGGA CGAACACCTGAATGTTCTGTAAAAGGTCGAACAGAAAGCTTTCATTGCCCTCCAGCACAGTCTTGTTACCCAGTAACTACCAAACATGAA TGTAGTGACAAGCTGGCCCAGTGCCGCCAAGCCAGACGAACTAGGTCTGAGGTCACATTGTTGTGGAAGAATAACCTTCCAATCATGGTG GAAATGATGCTACTACCAGACTGCTGCTACAGCGATGATGGGCCCACCACAGAGGGAATTGATCTAAATGATCCTGCGATTAAGCAAGAT GCATTATTATTAGAAAGATGGATCTTGGAGCCAGTTCCTCGACAGAATGGTGACCGATTTATTGAAGAGAAGACGCTTCTGTTGGCTGTC CGCTCATTTGTGTTTTTTTCTCAGTTAAGTGCATGGCTGAGTGTTTCTCATGGTGCTATTCCACGAAATATTCTCTACAGAATCAGTGCT GCTGATGTAGACCTACAGTGGAATTTTTCACAGACTCCAATTGAGCATGTGTTTCCTGTTCCCAATGTTTCTCACAATGTTGCCTTGAAA GTCAGTGTTCAGTCCTTGCCCAGACAATCTAATTATCCAGTTTTGACGTGCAGTATTCACACTAATATTGGCCTTTATGAGAAAAGAATT CAACAACATAAACTTAAAACTCATCAGCACCATAACCCAAATGAAGCAGAACAATGTGGTACAAACAGTTCACAGCGTCTGTGTAGCAAA CAAACTTGGACCATGGCACCTGAAAGTGTGTTACATGCAAAAAGTGGCCCAAGTCCAGAATATACTGCAGCTGTCAAAAATATCAAACTA TATCCAGGCACTGGCAGTAAATCTGACCATGGGACATCTCAAGCCAATATTCTAGGCTTTAGTGGTATAGGTGATATAAAATCACAAGAA ACATCAGTGAGAACTTTAAAATCATTTTCAATGGTTGATTCCAGTATCTCTAACCGCCAGAGTTTCTGGCAGTCAGCTGGTGAGACTAAC CCTTTAATAGGCTCTTTAATTCAGGAGCGGCAAGAAATCATTGCAAGAATTGCCCAACATTTGATTCATTGTGATCCAAGCACTTCACAT GTTTCTGGACGTCCATTTAATACTCAAGAGTCTAGTTCACTCCATTCAAAACTTTTCCGGGTTTCACAAGAAAATGAGAACGTGGGAAAA GGTAAAGAAGCTTTCTCCATGACTTTTGGTAGTCCAGAGTTTAGTTCCCCAGAAGACACCAATGAGGGGAAAATTCGACTAAAACCAGAA ACTCCTCGAAGTGAAACTTGTATTTCTAATGACTTTTATTCTCATATGCCTGTTGGAGAGACTAATCCTTTGATAGGCTCTTTACTCCAG GAGCGGCAAGATGTTATTGCAAGGATTGCTCAACACTTGGAGCACATTGATCCAACAGCATCACATATCCCCCGGCAGTCATTCAACATG CATGACTCCAGTTCGGTTGCATCTAAAGTGTTTAGGAGTTCATATGAAGACAAAAATTTGTTGAAGAAAAATAAGGATGAGTCCTCAGTT TCCATTTCTCACACAAAATGTTCCTTGTTAGGAGACATCAGTGATGGGAAAAACTTAGTACCTAATAAATGTTTTACTTCTTTTAAAAAT AATAGTAAAGAAAAGTGTTCTTTGAAACATCAAACAAGAAATCAGTGTCAGAACAATCCTAGTGAAATCATCCAAAGTACGTATCAGGAG ACACAGAACAAAAGTTCTAGTTTATCAACTTCCTCAATTTTGTCTCAGCACAAAGAAAATAACTTAGATTTGACAAGCAGATTCAAGGAG CAAGAAATGAGCAATGGAATTGATAAACAGTATTCAAATTGCACCACTATTGACAAACAGATTTGTACAAATAAGTATAAGGAAAAAATA ATAAATGAGAACTATAATCCAAAATTCTTTGGCAATCTTCAGTCTGATGATTCCAAAAAAAATGACTCAAAAATAAAAGTTACTGTGTTG GAAATGTCTGAATATTTGAACAAATATGAAAGCATGTCCTCAAATAAAGACTCAAAAAGGCCTAAGACATGTGAGCAAAATACTCAACTT AATAGCATAGAGAATTATCTCAATAAAGATAATGAAGGTTTCAAATGTAAAAAGTCAGACCAATTAAAAAATGAACAAGATAAGCAAGAA GATCCAACTAATGAAAAATCCCAAAACTATTCTCAGAGAAGAAGTATAAAAGACTGTTTGTCTACATGTGAGCAACCAAAAAATACAGAG GTATTGAGGACTACACTGAAACATTCAAATGTGTGGCGAAAACATAATTTTCATTCCTTGGATGGAACTTCAACCAGAGCCTTTCATCCT CAAACTGGATTGCCTCTTCTTTCAAGCCCTGTTCCTCAAAGAAAAACACAATCAGGTTGCTTTGATCTGGATTCTTCATTACTACATCTG AAAAGCTTCTCATCTAGAAGTCCTCGACCATGTTTAAACATTGAAGATGATCCAGATATTCATGAAAAACCATTTTTGAGTTCTAGTGCT CCACCTATAACAAGTCTTAGTCTCCTAGGAAATTTTGAGGAATCTGTCTTGAACTATCGTTTCGATCCTCTCGGCATTGTTGATGGTTTT ACTGCCGAGGTAGGGGCAAGTGGTGCTTTCTGCCCCACACATTTGACTCTTCCAGTTGAAGTGTCATTCTACAGTGTTTCAGATGACAAT GCTCCCTCTCCTTATATGCTTGATGATTCCCTGAATCAGATCCGTAAGCTCCAGAGGTCTCTGGATGAAGAGAAAGAAAGAAATGAAAAC >In-frame_FAM214A_ENST00000261844_chr15_52885775_-_CCDC102B_ENST00000360242_chr18_66721267_+_2916nt ATGAAGCCAGACCGAGATACTCTGGATGAATATTTTGAATATGATGCAGAGGAGTTCTTGGTCTCTTTGGCCTTGCTGATAACAGAAGGA CGAACACCTGAATGTTCTGTAAAAGGTCGAACAGAAAGCTTTCATTGCCCTCCAGCACAGTCTTGTTACCCAGTAACTACCAAACATGAA TGTAGTGACAAGCTGGCCCAGTGCCGCCAAGCCAGACGAACTAGGTCTGAGGTCACATTGTTGTGGAAGAATAACCTTCCAATCATGGTG GAAATGATGCTACTACCAGACTGCTGCTACAGCGATGATGGGCCCACCACAGAGGGAATTGATCTAAATGATCCTGCGATTAAGCAAGAT GCATTATTATTAGAAAGATGGATCTTGGAGCCAGTTCCTCGACAGAATGGTGACCGATTTATTGAAGAGAAGACGCTTCTGTTGGCTGTC CGCTCATTTGTGTTTTTTTCTCAGTTAAGTGCATGGCTGAGTGTTTCTCATGGTGCTATTCCACGAAATATTCTCTACAGAATCAGTGCT GCTGATGTAGACCTACAGTGGAATTTTTCACAGACTCCAATTGAGCATGTGTTTCCTGTTCCCAATGTTTCTCACAATGTTGCCTTGAAA GTCAGTGTTCAGTCCTTGCCCAGACAATCTAATTATCCAGTTTTGACGTGCAGTATTCACACTAATATTGGCCTTTATGAGAAAAGAATT CAACAACATAAACTTAAAACTCATCAGCACCATAACCCAAATGAAGCAGAACAATGTGGTACAAACAGTTCACAGCGTCTGTGTAGCAAA CAAACTTGGACCATGGCACCTGAAAGTGTGTTACATGCAAAAAGTGGCCCAAGTCCAGAATATACTGCAGCTGTCAAAAATATCAAACTA TATCCAGGCACTGGCAGTAAATCTGACCATGGGACATCTCAAGCCAATATTCTAGGCTTTAGTGGTATAGGTGATATAAAATCACAAGAA ACATCAGTGAGAACTTTAAAATCATTTTCAATGGTTGATTCCAGTATCTCTAACCGCCAGAGTTTCTGGCAGTCAGCTGGTGAGACTAAC CCTTTAATAGGCTCTTTAATTCAGGAGCGGCAAGAAATCATTGCAAGAATTGCCCAACATTTGATTCATTGTGATCCAAGCACTTCACAT GTTTCTGGACGTCCATTTAATACTCAAGAGTCTAGTTCACTCCATTCAAAACTTTTCCGGGTTTCACAAGAAAATGAGAACGTGGGAAAA GGTAAAGAAGCTTTCTCCATGACTTTTGGTAGTCCAGAGTTTAGTTCCCCAGAAGACACCAATGAGGGGAAAATTCGACTAAAACCAGAA ACTCCTCGAAGTGAAACTTGTATTTCTAATGACTTTTATTCTCATATGCCTGTTGGAGAGACTAATCCTTTGATAGGCTCTTTACTCCAG GAGCGGCAAGATGTTATTGCAAGGATTGCTCAACACTTGGAGCACATTGATCCAACAGCATCACATATCCCCCGGCAGTCATTCAACATG CATGACTCCAGTTCGGTTGCATCTAAAGTGTTTAGGAGTTCATATGAAGACAAAAATTTGTTGAAGAAAAATAAGGATGAGTCCTCAGTT TCCATTTCTCACACAAAATGTTCCTTGTTAGGAGACATCAGTGATGGGAAAAACTTAGTACCTAATAAATGTTTTACTTCTTTTAAAAAT AATAGTAAAGAAAAGTGTTCTTTGAAACATCAAACAAGAAATCAGTGTCAGAACAATCCTAGTGAAATCATCCAAAGTACGTATCAGGAG ACACAGAACAAAAGTTCTAGTTTATCAACTTCCTCAATTTTGTCTCAGCACAAAGAAAATAACTTAGATTTGACAAGCAGATTCAAGGAG CAAGAAATGAGCAATGGAATTGATAAACAGTATTCAAATTGCACCACTATTGACAAACAGATTTGTACAAATAAGTATAAGGAAAAAATA ATAAATGAGAACTATAATCCAAAATTCTTTGGCAATCTTCAGTCTGATGATTCCAAAAAAAATGACTCAAAAATAAAAGTTACTGTGTTG GAAATGTCTGAATATTTGAACAAATATGAAAGCATGTCCTCAAATAAAGACTCAAAAAGGCCTAAGACATGTGAGCAAAATACTCAACTT AATAGCATAGAGAATTATCTCAATAAAGATAATGAAGGTTTCAAATGTAAAAAGTCAGACCAATTAAAAAATGAACAAGATAAGCAAGAA GATCCAACTAATGAAAAATCCCAAAACTATTCTCAGAGAAGAAGTATAAAAGACTGTTTGTCTACATGTGAGCAACCAAAAAATACAGAG GTATTGAGGACTACACTGAAACATTCAAATGTGTGGCGAAAACATAATTTTCATTCCTTGGATGGAACTTCAACCAGAGCCTTTCATCCT CAAACTGGATTGCCTCTTCTTTCAAGCCCTGTTCCTCAAAGAAAAACACAATCAGGTTGCTTTGATCTGGATTCTTCATTACTACATCTG AAAAGCTTCTCATCTAGAAGTCCTCGACCATGTTTAAACATTGAAGATGATCCAGATATTCATGAAAAACCATTTTTGAGTTCTAGTGCT CCACCTATAACAAGTCTTAGTCTCCTAGGAAATTTTGAGGAATCTGTCTTGAACTATCGTTTCGATCCTCTCGGCATTGTTGATGGTTTT ACTGCCGAGGTAGGGGCAAGTGGTGCTTTCTGCCCCACACATTTGACTCTTCCAGTTGAAGTGTCATTCTACAGTGTTTCAGATGACAAT GCTCCCTCTCCTTATATGCTTGATGATTCCCTGAATCAGATCCGTAAGCTCCAGAGGTCTCTGGATGAAGAGAAAGAAAGAAATGAAAAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FAM214A_ENST00000261844_chr15_52885775_-_CCDC102B_ENST00000319445_chr18_66721267_+_4121nt TAAACTTGGCCGCGGTTGCCGCAGGAAGGCTAGCCAGAGGGTAATTACACAGCATTTTGAAAGCGAAGCAGAAGCCGTAGAATCAGCGGC GAGCCTGTTGAAAGAACCCACAGGTGCATTTCACAGCACTCTGGGCGAAAATTGGATGTGAAAATGAAGCCAGACCGAGATACTCTGGAT GAATATTTTGAATATGATGCAGAGGAGTTCTTGGTCTCTTTGGCCTTGCTGATAACAGAAGGACGAACACCTGAATGTTCTGTAAAAGGT CGAACAGAAAGCTTTCATTGCCCTCCAGCACAGTCTTGTTACCCAGTAACTACCAAACATGAATGTAGTGACAAGCTGGCCCAGTGCCGC CAAGCCAGACGAACTAGGTCTGAGGTCACATTGTTGTGGAAGAATAACCTTCCAATCATGGTGGAAATGATGCTACTACCAGACTGCTGC TACAGCGATGATGGGCCCACCACAGAGGGAATTGATCTAAATGATCCTGCGATTAAGCAAGATGCATTATTATTAGAAAGATGGATCTTG GAGCCAGTTCCTCGACAGAATGGTGACCGATTTATTGAAGAGAAGACGCTTCTGTTGGCTGTCCGCTCATTTGTGTTTTTTTCTCAGTTA AGTGCATGGCTGAGTGTTTCTCATGGTGCTATTCCACGAAATATTCTCTACAGAATCAGTGCTGCTGATGTAGACCTACAGTGGAATTTT TCACAGACTCCAATTGAGCATGTGTTTCCTGTTCCCAATGTTTCTCACAATGTTGCCTTGAAAGTCAGTGTTCAGTCCTTGCCCAGACAA TCTAATTATCCAGTTTTGACGTGCAGTATTCACACTAATATTGGCCTTTATGAGAAAAGAATTCAACAACATAAACTTAAAACTCATCAG CACCATAACCCAAATGAAGCAGAACAATGTGGTACAAACAGTTCACAGCGTCTGTGTAGCAAACAAACTTGGACCATGGCACCTGAAAGT GTGTTACATGCAAAAAGTGGCCCAAGTCCAGAATATACTGCAGCTGTCAAAAATATCAAACTATATCCAGGCACTGGCAGTAAATCTGAC CATGGGACATCTCAAGCCAATATTCTAGGCTTTAGTGGTATAGGTGATATAAAATCACAAGAAACATCAGTGAGAACTTTAAAATCATTT TCAATGGTTGATTCCAGTATCTCTAACCGCCAGAGTTTCTGGCAGTCAGCTGGTGAGACTAACCCTTTAATAGGCTCTTTAATTCAGGAG CGGCAAGAAATCATTGCAAGAATTGCCCAACATTTGATTCATTGTGATCCAAGCACTTCACATGTTTCTGGACGTCCATTTAATACTCAA GAGTCTAGTTCACTCCATTCAAAACTTTTCCGGGTTTCACAAGAAAATGAGAACGTGGGAAAAGGTAAAGAAGCTTTCTCCATGACTTTT GGTAGTCCAGAGTTTAGTTCCCCAGAAGACACCAATGAGGGGAAAATTCGACTAAAACCAGAAACTCCTCGAAGTGAAACTTGTATTTCT AATGACTTTTATTCTCATATGCCTGTTGGAGAGACTAATCCTTTGATAGGCTCTTTACTCCAGGAGCGGCAAGATGTTATTGCAAGGATT GCTCAACACTTGGAGCACATTGATCCAACAGCATCACATATCCCCCGGCAGTCATTCAACATGCATGACTCCAGTTCGGTTGCATCTAAA GTGTTTAGGAGTTCATATGAAGACAAAAATTTGTTGAAGAAAAATAAGGATGAGTCCTCAGTTTCCATTTCTCACACAAAATGTTCCTTG TTAGGAGACATCAGTGATGGGAAAAACTTAGTACCTAATAAATGTTTTACTTCTTTTAAAAATAATAGTAAAGAAAAGTGTTCTTTGAAA CATCAAACAAGAAATCAGTGTCAGAACAATCCTAGTGAAATCATCCAAAGTACGTATCAGGAGACACAGAACAAAAGTTCTAGTTTATCA ACTTCCTCAATTTTGTCTCAGCACAAAGAAAATAACTTAGATTTGACAAGCAGATTCAAGGAGCAAGAAATGAGCAATGGAATTGATAAA CAGTATTCAAATTGCACCACTATTGACAAACAGATTTGTACAAATAAGTATAAGGAAAAAATAATAAATGAGAACTATAATCCAAAATTC TTTGGCAATCTTCAGTCTGATGATTCCAAAAAAAATGACTCAAAAATAAAAGTTACTGTGTTGGAAATGTCTGAATATTTGAACAAATAT GAAAGCATGTCCTCAAATAAAGACTCAAAAAGGCCTAAGACATGTGAGCAAAATACTCAACTTAATAGCATAGAGAATTATCTCAATAAA GATAATGAAGGTTTCAAATGTAAAAAGTCAGACCAATTAAAAAATGAACAAGATAAGCAAGAAGATCCAACTAATGAAAAATCCCAAAAC TATTCTCAGAGAAGAAGTATAAAAGACTGTTTGTCTACATGTGAGCAACCAAAAAATACAGAGGTATTGAGGACTACACTGAAACATTCA AATGTGTGGCGAAAACATAATTTTCATTCCTTGGATGGAACTTCAACCAGAGCCTTTCATCCTCAAACTGGATTGCCTCTTCTTTCAAGC CCTGTTCCTCAAAGAAAAACACAATCAGGTTGCTTTGATCTGGATTCTTCATTACTACATCTGAAAAGCTTCTCATCTAGAAGTCCTCGA CCATGTTTAAACATTGAAGATGATCCAGATATTCATGAAAAACCATTTTTGAGTTCTAGTGCTCCACCTATAACAAGTCTTAGTCTCCTA GGAAATTTTGAGGAATCTGTCTTGAACTATCGTTTCGATCCTCTCGGCATTGTTGATGGTTTTACTGCCGAGGTAGGGGCAAGTGGTGCT TTCTGCCCCACACATTTGACTCTTCCAGTTGAAGTGTCATTCTACAGTGTTTCAGATGACAATGCTCCCTCTCCTTATATGCTTGATGAT TCCCTGAATCAGATCCGTAAGCTCCAGAGGTCTCTGGATGAAGAGAAAGAAAGAAATGAAAACTTAGAGACTGAACTCAGGCACTTGCAA AACTGGTAATTTTTTCACAAAATATGCTGAATTAAAGATTAGGGCCTTAAAGACATTTCCATATCCTTTTCTTAAATATCAGTAAAATTG TTTTTATTAACTAGAAATATTAATGAAAAAAACGTAGACAATACACAAATTAATGGGCTTCTTCACTTCTTCTAATTTTTGCCTAACAGA TACTGCATATTCTCAAAAAGACAATTTAAATGTCATTTAAAAACAACTTTAATTCTAAGATGTGTAAATATTTTGAAAGTCAAAAAGGGC TTTCAGAATACTTTTTACATAAAATCTGAAAGAGTTATAATATCGGTAAGAAAAAGTAAGTTGAAAACCATACAAGACGCTGGGTCATTA ATAAGAAAACCATTGACTTTAAGTATAAAGTACTGGTTTGTTTAAATAATTGGTAAACTTTTATGTACGTGTTGTCTATGTGGTGGGGAT GGCAGGTTGTATTAACAAAAATGAATCATTCTAGAGGTGTAACAATACATTTCTTATATAATTTTATAAGTCATTTCTAATCTTTGTATA AAACAGAAGTGAGCAGATGAATCAGAAAAAAGTGTTTTGTATTTTAAAGTAACAGATAACCAGTGATTGAATCTAAGACAGGCTGTAAGC ATCGCTGAGAAACTAAAAGGACTTTTGACTTTTATCTGGATAGACATTTCTACAGTAAAATCATGGAAAGGCATCAGCATTGCAAAGTAG CATCTAGGTAGAAATCAGGCCAAAATTAAGCTGTGGTTTCCCTCTGAGTAGTGGGAATAGAGAAAATTAGGAAATTGTGGTTATGTGAAT ATTTCTTTAAAACTTTTATGTACATTATAGTTTATTGCTTCATATTTAAGTTTAGTTTTTAAGGTAAAATGTTATTTTGAACAAAAAGAC ACTTATAATTTTCCATACCTATTTTCAACTGAAGGCAACTTGTAAGATTTAACTCAGTCAATAACATACTGGTTTTACTCATCTCCCCCT >In-frame_FAM214A_ENST00000261844_chr15_52885775_-_CCDC102B_ENST00000360242_chr18_66721267_+_4121nt TAAACTTGGCCGCGGTTGCCGCAGGAAGGCTAGCCAGAGGGTAATTACACAGCATTTTGAAAGCGAAGCAGAAGCCGTAGAATCAGCGGC GAGCCTGTTGAAAGAACCCACAGGTGCATTTCACAGCACTCTGGGCGAAAATTGGATGTGAAAATGAAGCCAGACCGAGATACTCTGGAT GAATATTTTGAATATGATGCAGAGGAGTTCTTGGTCTCTTTGGCCTTGCTGATAACAGAAGGACGAACACCTGAATGTTCTGTAAAAGGT CGAACAGAAAGCTTTCATTGCCCTCCAGCACAGTCTTGTTACCCAGTAACTACCAAACATGAATGTAGTGACAAGCTGGCCCAGTGCCGC CAAGCCAGACGAACTAGGTCTGAGGTCACATTGTTGTGGAAGAATAACCTTCCAATCATGGTGGAAATGATGCTACTACCAGACTGCTGC TACAGCGATGATGGGCCCACCACAGAGGGAATTGATCTAAATGATCCTGCGATTAAGCAAGATGCATTATTATTAGAAAGATGGATCTTG GAGCCAGTTCCTCGACAGAATGGTGACCGATTTATTGAAGAGAAGACGCTTCTGTTGGCTGTCCGCTCATTTGTGTTTTTTTCTCAGTTA AGTGCATGGCTGAGTGTTTCTCATGGTGCTATTCCACGAAATATTCTCTACAGAATCAGTGCTGCTGATGTAGACCTACAGTGGAATTTT TCACAGACTCCAATTGAGCATGTGTTTCCTGTTCCCAATGTTTCTCACAATGTTGCCTTGAAAGTCAGTGTTCAGTCCTTGCCCAGACAA TCTAATTATCCAGTTTTGACGTGCAGTATTCACACTAATATTGGCCTTTATGAGAAAAGAATTCAACAACATAAACTTAAAACTCATCAG CACCATAACCCAAATGAAGCAGAACAATGTGGTACAAACAGTTCACAGCGTCTGTGTAGCAAACAAACTTGGACCATGGCACCTGAAAGT GTGTTACATGCAAAAAGTGGCCCAAGTCCAGAATATACTGCAGCTGTCAAAAATATCAAACTATATCCAGGCACTGGCAGTAAATCTGAC CATGGGACATCTCAAGCCAATATTCTAGGCTTTAGTGGTATAGGTGATATAAAATCACAAGAAACATCAGTGAGAACTTTAAAATCATTT TCAATGGTTGATTCCAGTATCTCTAACCGCCAGAGTTTCTGGCAGTCAGCTGGTGAGACTAACCCTTTAATAGGCTCTTTAATTCAGGAG CGGCAAGAAATCATTGCAAGAATTGCCCAACATTTGATTCATTGTGATCCAAGCACTTCACATGTTTCTGGACGTCCATTTAATACTCAA GAGTCTAGTTCACTCCATTCAAAACTTTTCCGGGTTTCACAAGAAAATGAGAACGTGGGAAAAGGTAAAGAAGCTTTCTCCATGACTTTT GGTAGTCCAGAGTTTAGTTCCCCAGAAGACACCAATGAGGGGAAAATTCGACTAAAACCAGAAACTCCTCGAAGTGAAACTTGTATTTCT AATGACTTTTATTCTCATATGCCTGTTGGAGAGACTAATCCTTTGATAGGCTCTTTACTCCAGGAGCGGCAAGATGTTATTGCAAGGATT GCTCAACACTTGGAGCACATTGATCCAACAGCATCACATATCCCCCGGCAGTCATTCAACATGCATGACTCCAGTTCGGTTGCATCTAAA GTGTTTAGGAGTTCATATGAAGACAAAAATTTGTTGAAGAAAAATAAGGATGAGTCCTCAGTTTCCATTTCTCACACAAAATGTTCCTTG TTAGGAGACATCAGTGATGGGAAAAACTTAGTACCTAATAAATGTTTTACTTCTTTTAAAAATAATAGTAAAGAAAAGTGTTCTTTGAAA CATCAAACAAGAAATCAGTGTCAGAACAATCCTAGTGAAATCATCCAAAGTACGTATCAGGAGACACAGAACAAAAGTTCTAGTTTATCA ACTTCCTCAATTTTGTCTCAGCACAAAGAAAATAACTTAGATTTGACAAGCAGATTCAAGGAGCAAGAAATGAGCAATGGAATTGATAAA CAGTATTCAAATTGCACCACTATTGACAAACAGATTTGTACAAATAAGTATAAGGAAAAAATAATAAATGAGAACTATAATCCAAAATTC TTTGGCAATCTTCAGTCTGATGATTCCAAAAAAAATGACTCAAAAATAAAAGTTACTGTGTTGGAAATGTCTGAATATTTGAACAAATAT GAAAGCATGTCCTCAAATAAAGACTCAAAAAGGCCTAAGACATGTGAGCAAAATACTCAACTTAATAGCATAGAGAATTATCTCAATAAA GATAATGAAGGTTTCAAATGTAAAAAGTCAGACCAATTAAAAAATGAACAAGATAAGCAAGAAGATCCAACTAATGAAAAATCCCAAAAC TATTCTCAGAGAAGAAGTATAAAAGACTGTTTGTCTACATGTGAGCAACCAAAAAATACAGAGGTATTGAGGACTACACTGAAACATTCA AATGTGTGGCGAAAACATAATTTTCATTCCTTGGATGGAACTTCAACCAGAGCCTTTCATCCTCAAACTGGATTGCCTCTTCTTTCAAGC CCTGTTCCTCAAAGAAAAACACAATCAGGTTGCTTTGATCTGGATTCTTCATTACTACATCTGAAAAGCTTCTCATCTAGAAGTCCTCGA CCATGTTTAAACATTGAAGATGATCCAGATATTCATGAAAAACCATTTTTGAGTTCTAGTGCTCCACCTATAACAAGTCTTAGTCTCCTA GGAAATTTTGAGGAATCTGTCTTGAACTATCGTTTCGATCCTCTCGGCATTGTTGATGGTTTTACTGCCGAGGTAGGGGCAAGTGGTGCT TTCTGCCCCACACATTTGACTCTTCCAGTTGAAGTGTCATTCTACAGTGTTTCAGATGACAATGCTCCCTCTCCTTATATGCTTGATGAT TCCCTGAATCAGATCCGTAAGCTCCAGAGGTCTCTGGATGAAGAGAAAGAAAGAAATGAAAACTTAGAGACTGAACTCAGGCACTTGCAA AACTGGTAATTTTTTCACAAAATATGCTGAATTAAAGATTAGGGCCTTAAAGACATTTCCATATCCTTTTCTTAAATATCAGTAAAATTG TTTTTATTAACTAGAAATATTAATGAAAAAAACGTAGACAATACACAAATTAATGGGCTTCTTCACTTCTTCTAATTTTTGCCTAACAGA TACTGCATATTCTCAAAAAGACAATTTAAATGTCATTTAAAAACAACTTTAATTCTAAGATGTGTAAATATTTTGAAAGTCAAAAAGGGC TTTCAGAATACTTTTTACATAAAATCTGAAAGAGTTATAATATCGGTAAGAAAAAGTAAGTTGAAAACCATACAAGACGCTGGGTCATTA ATAAGAAAACCATTGACTTTAAGTATAAAGTACTGGTTTGTTTAAATAATTGGTAAACTTTTATGTACGTGTTGTCTATGTGGTGGGGAT GGCAGGTTGTATTAACAAAAATGAATCATTCTAGAGGTGTAACAATACATTTCTTATATAATTTTATAAGTCATTTCTAATCTTTGTATA AAACAGAAGTGAGCAGATGAATCAGAAAAAAGTGTTTTGTATTTTAAAGTAACAGATAACCAGTGATTGAATCTAAGACAGGCTGTAAGC ATCGCTGAGAAACTAAAAGGACTTTTGACTTTTATCTGGATAGACATTTCTACAGTAAAATCATGGAAAGGCATCAGCATTGCAAAGTAG CATCTAGGTAGAAATCAGGCCAAAATTAAGCTGTGGTTTCCCTCTGAGTAGTGGGAATAGAGAAAATTAGGAAATTGTGGTTATGTGAAT ATTTCTTTAAAACTTTTATGTACATTATAGTTTATTGCTTCATATTTAAGTTTAGTTTTTAAGGTAAAATGTTATTTTGAACAAAAAGAC ACTTATAATTTTCCATACCTATTTTCAACTGAAGGCAACTTGTAAGATTTAACTCAGTCAATAACATACTGGTTTTACTCATCTCCCCCT |
Top |
FusionGenePPI for FAM214A_CCDC102B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FAM214A | APC, LIG4, GOLGA2, MAGEA6, TRIM27, MID2, SSX2IP, KRT40 | CCDC102B | MARK1, ARL4D, BYSL, EHHADH, GEM, SFN, KIFC3, MCM7, MOS, CDK18, PSMA1, TRIM27, SDCBP, TPM3, ZNF20, LMO4, ARL4A, ABI2, HMG20B, MAB21L2, EXOC5, FAM127B, RSPH14, SPG21, POP5, CCHCR1, WDYHV1, MAGOHB, RCOR3, NXT2, GOPC, TRIM54, ZNF250, NIF3L1, C20orf195, LENG1, CCDC102B, CCDC33, SLIRP, ENKD1, FAM161A, LNX1, CEP19, FBF1, CCDC120, SYCE1, CCDC101, PNMA5, ZNF572, AK8, PPP1R18, CEP57L1, FAM127C, CCDC102A, VPS26B, TARSL2, GULP1, USF2, ZNF622, SNX1, TJP1, HDLBP, FGD6, TAB2, SAMD1, RGP1, TAB1, RAD21, NFRKB, SNX5, TRAPPC6B, RARS, MAP3K7, UBXN1, SH2B1, SASS6, XBP1, CDK1, PDCD2L, UACA, TRAPPC4, SNX6, CGN, DCTN6, FBXO7, SRP54, C2CD5, DCP1B, EDC3, SEH1L, SPRTN, ARRB2, PSMD6, TRAPPC10, STAG2, ARFGAP3, TRAPPC3, TARS |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for FAM214A_CCDC102B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for FAM214A_CCDC102B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|