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Fusion gene ID: 12431 |
FusionGeneSummary for FAF1_LRRC7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FAF1_LRRC7 | Fusion gene ID: 12431 | Hgene | Tgene | Gene symbol | FAF1 | LRRC7 | Gene ID | 11124 | 57554 |
| Gene name | Fas associated factor 1 | leucine rich repeat containing 7 | |
| Synonyms | CGI-03|HFAF1s|UBXD12|UBXN3A|hFAF1 | DENSIN | |
| Cytomap | 1p32.3 | 1p31.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | FAS-associated factor 1Fas (TNFRSF6) associated factor 1TNFRSF6-associated factor 1UBX domain protein 3AUBX domain-containing protein 12UBX domain-containing protein 3A | leucine-rich repeat-containing protein 7densin-180 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9UNN5 | Q96NW7 | |
| Ensembl transtripts involved in fusion gene | ENST00000396153, ENST00000371778, ENST00000545823, ENST00000472808, | ENST00000310961, ENST00000370958, ENST00000035383, ENST00000415775, ENST00000565615, | |
| Fusion gene scores | * DoF score | 15 X 10 X 8=1200 | 4 X 4 X 2=32 |
| # samples | 21 | 4 | |
| ** MAII score | log2(21/1200*10)=-2.51457317282976 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: FAF1 [Title/Abstract] AND LRRC7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | FAF1 | GO:0010942 | positive regulation of cell death | 15596450 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-BH-A209-01A | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000396153 | ENST00000310961 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| In-frame | ENST00000396153 | ENST00000370958 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| In-frame | ENST00000396153 | ENST00000035383 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| 5CDS-5UTR | ENST00000396153 | ENST00000415775 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| 5CDS-intron | ENST00000396153 | ENST00000565615 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| Frame-shift | ENST00000371778 | ENST00000310961 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| Frame-shift | ENST00000371778 | ENST00000370958 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| Frame-shift | ENST00000371778 | ENST00000035383 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| 5CDS-5UTR | ENST00000371778 | ENST00000415775 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| 5CDS-intron | ENST00000371778 | ENST00000565615 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| intron-3CDS | ENST00000545823 | ENST00000310961 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| intron-3CDS | ENST00000545823 | ENST00000370958 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| intron-3CDS | ENST00000545823 | ENST00000035383 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| intron-5UTR | ENST00000545823 | ENST00000415775 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| intron-intron | ENST00000545823 | ENST00000565615 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| intron-3CDS | ENST00000472808 | ENST00000310961 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| intron-3CDS | ENST00000472808 | ENST00000370958 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| intron-3CDS | ENST00000472808 | ENST00000035383 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| intron-5UTR | ENST00000472808 | ENST00000415775 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
| intron-intron | ENST00000472808 | ENST00000565615 | FAF1 | chr1 | 51323601 | - | LRRC7 | chr1 | 70257726 | + |
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FusionProtFeatures for FAF1_LRRC7 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FAF1 | LRRC7 |
| Ubiquitin-binding protein (PubMed:19722279). Requiredfor the progression of DNA replication forks by targeting DNAreplication licensing factor CDT1 for degradation(PubMed:26842564). Potentiates but cannot initiate FAS-inducedapoptosis (By similarity). {ECO:0000250|UniProtKB:P54731,ECO:0000269|PubMed:19722279, ECO:0000269|PubMed:26842564}. | Required for normal synaptic spine architecture andfunction. Necessary for DISC1 and GRM5 localization topostsynaptic density complexes and for both N-methyl D-aspartatereceptor-dependent and metabotropic glutamate receptor-dependentlong term depression. {ECO:0000269|PubMed:11729199}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 1445_1535 | 63 | 1538 | Domain | PDZ |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 116_137 | 63 | 1538 | Repeat | Note=LRR 5 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 139_161 | 63 | 1538 | Repeat | Note=LRR 6 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 162_183 | 63 | 1538 | Repeat | Note=LRR 7 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 185_206 | 63 | 1538 | Repeat | Note=LRR 8 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 208_229 | 63 | 1538 | Repeat | Note=LRR 9 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 231_253 | 63 | 1538 | Repeat | Note=LRR 10 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 254_275 | 63 | 1538 | Repeat | Note=LRR 11 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 277_298 | 63 | 1538 | Repeat | Note=LRR 12 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 300_321 | 63 | 1538 | Repeat | Note=LRR 13 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 323_344 | 63 | 1538 | Repeat | Note=LRR 14 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 346_367 | 63 | 1538 | Repeat | Note=LRR 15 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 369_391 | 63 | 1538 | Repeat | Note=LRR 16 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 392_413 | 63 | 1538 | Repeat | Note=LRR 17 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 70_91 | 63 | 1538 | Repeat | Note=LRR 3 |
| Tgene | >LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 93_114 | 63 | 1538 | Repeat | Note=LRR 4 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >FAF1 | chr1:51323601 | chr1:70257726 | ENST00000371778 | - | 3 | 20 | 1_57 | 38 | 651 | Domain | UBA |
| Hgene | >FAF1 | chr1:51323601 | chr1:70257726 | ENST00000371778 | - | 3 | 20 | 569_646 | 38 | 651 | Domain | UBX |
| Hgene | >FAF1 | chr1:51323601 | chr1:70257726 | ENST00000396153 | - | 2 | 19 | 1_57 | 38 | 651 | Domain | UBA |
| Hgene | >FAF1 | chr1:51323601 | chr1:70257726 | ENST00000396153 | - | 2 | 19 | 569_646 | 38 | 651 | Domain | UBX |
| Tgene | LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 23_44 | 63 | 1538 | Repeat | Note=LRR 1 |
| Tgene | LRRC7 | chr1:51323601 | chr1:70257726 | ENST00000035383 | + | 0 | 25 | 47_68 | 63 | 1538 | Repeat | Note=LRR 2 |
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FusionGeneSequence for FAF1_LRRC7 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_FAF1_ENST00000396153_chr1_51323601_-_LRRC7_ENST00000310961_chr1_70257726_+_1466aa MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQ IQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI GNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPF SFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEDKKEDDENAGK VKDLSCQAPWERGQRGITLQPARLSGDCCTPWARCDQQIQDMPVPQNDPQLAWGCISGLQQERSMCTPLPVAAQSTTLPSLSGRQVEINL KRYPTPYPEDLKNMVKSVQNLVGKPSHGVRVENSNPTANTEQTVKEKYEHKWPVAPKEITVEDSFVHPANEMRIGELHPSLAETPLYPPK LVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSGSSNTRVKVGSLQTTAKDAVHNSLWGNRIAPSFPQPLDSKPLLSQREA VPPGNIPQRPDRLPMSDTFTDNWTDGSHYDNTGFVAEETTAENANSNPLLSSKSRSTSSHGRRPLIRQDRIVGVPLELEQSTHRHTPETE VPPSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKEHIKESTEIPSPFSPGVPWEYHDSNPNRSLSNVFSQIHCRPESSKGVISI SKSTERLSPLMKDIKSNKFKKSQSIDEIDIGTYKVYNIPLENYASGSDHLGSHERPDKMLGPEHGMSSMSRSQSVPMLDDEMLTYGSSKG PQQQKASMTKKVYQFDQSFNPQGSVEVKAEKRIPPPFQHNPEYVQQASKNIAKDLISPRAYRGYPPMEQMFSFSQPSVNEDAVVNAQFAS QGARAGFLRRADSLVSATEMAMFRRVNEPHELPPTDRYGRPPYRGGLDRQSSVTVTESQFLKRNGRYEDEHPSYQEVKAQAGSFPVKNLT QRRPLSARSYSTESYGASQTRPVSARPTMAALLEKIPSDYNLGNYGDKPSDNSDLKTRPTPVKGEESCGKMPADWRQQLLRHIEARRLDR TPSQQSNILDNGQEDVSPSGQWNPYPLGRRDVPPDTITKKAGSHIQTLMGSQSLQHRSREQQPYEGNINKVTIQQFQSPLPIQIPSSQAT RGPQPGRCLIQTKGQRSMDGYPEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASNLLQPGDKILQANGHSFVHME >In-frame_FAF1_ENST00000396153_chr1_51323601_-_LRRC7_ENST00000370958_chr1_70257726_+_155aa MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK >In-frame_FAF1_ENST00000396153_chr1_51323601_-_LRRC7_ENST00000035383_chr1_70257726_+_1513aa MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQ IQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTI GNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPF SFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEDKKEDDENAGK VKDLSCQAPWERGQRGITLQPARLSGDCCTPWARCDQQIQDMPVPQNDPQLAWGCISGLQQERSMCTPLPVAAQSTTLPSLSGRQVEINL KRYPTPYPEDLKNMVKSVQNLVGKPSHGVRVENSNPTANTEQTVKEKYEHKWPVAPKEITVEDSFVHPANEMRIGELHPSLAETPLYPPK LVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSGSSNTRVKVGSLQTTAKDAVHNSLWGNRIAPSFPQPLDSKPLLSQREA VPPGNIPQRPDRLPMSDTFTDNWTDGSHYDNTGFVAEETTAENANSNPLLSSKSRSTSSHGRRPLIRQDRIVGVPLELEQSTHRHTPETE VPPSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKEHIKESTEIPSPFSPGVPWEYHDSNPNRSLSNVFSQIHCRPESSKGVISI SKSTERLSPLMKDIKSNKFKKSQSIDEIDIGTYKVYNIPLENYASGSDHLGSHERPDKMLGPEHGMSSMSRSQSVPMLDDEMLTYGSSKG PQQQKASMTKKVYQFDQSFNPQGSVEVKAEKRIPPPFQHNPEYVQQASKNIAKDLISPRAYRGYPPMEQMFSFSQPSVNEDAVVNAQFAS QGARAGFLRRADSLVSATEMAMFRRVNEPHELPPTDRYGRPPYRGGLDRQSSVTVTESQFLKRNGRYEDEHPSYQEVKAQAGSFPVKNLT QRRPLSARSYSTESYGASQTRPVSARPTMAALLEKIPSDYNLGNYGDKPSDNSDLKTRPTPVKGEESCGKMPADWRQQLLRHIEARRLDR NAAYKHNTVNLGMLPYGGISAMHAGRSMTLNLQTKSKFDHQELPLQKTPSQQSNILDNGQEDVSPSGQWNPYPLGRRDVPPDTITKKAGS HIQTLMGSQSLQHRSREQQPYEGNINKVTIQQFQSPLPIQIPSSQATRGPQPGRCLIQTKGQRSMDGYPEQFCVRIEKNPGLGFSISGGI |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_FAF1_ENST00000396153_chr1_51323601_-_LRRC7_ENST00000310961_chr1_70257726_+_4398nt ATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGCTT GAACAAAATAATTGGGACTTAGTGCAATTGTTCAACTGTCAAGCTCTACGAAAACTAAGTATTCCTGATAACGACCTTTCAAATCTGCCA ACCACTATTGCTAGTTTAGTTAATCTTAAAGAACTCGACATCAGTAAAAATGGTGTACAAGAATTTCCAGAAAACATAAAGTGCTGTAAG TGTTTAACAATTATTGAAGCCAGTGTCAATCCCATTTCTAAACTACCTGATGGCTTCACACAGCTCCTAAACCTGACCCAGCTCTACCTG AATGACGCCTTTCTTGAATTTCTTCCAGCCAATTTTGGAAGACTTGTCAAATTGCGGATCTTGGAGTTAAGAGAAAATCACTTGAAAACT CTACCAAAGTCAATGCACAAACTGGCCCAGTTGGAAAGACTTGACCTAGGCAATAATGAATTCGGTGAGCTGCCTGAAGTTCTGGATCAA ATACAAAATTTGAGGGAGTTATGGATGGATAATAATGCATTACAAGTGTTACCTGGGTCTATAGGGAAGTTAAAGATGTTGGTATACCTG GATATGTCAAAAAACAGAATAGAAACAGTTGACATGGACATTTCTGGATGTGAAGCCCTTGAGGACCTCTTATTGTCATCCAATATGTTG CAACAATTGCCTGATTCTATAGGACTTTTGAAAAAACTAACAACTCTAAAAGTAGATGACAATCAACTTACAATGCTACCCAATACAATT GGAAATTTATCTTTATTAGAAGAATTTGACTGTAGCTGTAATGAACTGGAGTCACTACCTTCTACTATTGGCTACCTTCATAGTCTTCGG ACATTAGCAGTTGATGAGAATTTCCTTCCAGAATTACCCAGAGAAATTGGAAGTTGTAAGAATGTAACAGTCATGTCTCTACGCTCCAAC AAATTAGAATTTCTTCCTGAAGAGATTGGACAGATGCAGAAACTAAGAGTCCTAAATTTGAGTGACAACAGATTGAAGAATTTACCATTC TCATTTACCAAACTTAAAGAGCTTGCAGCTTTGTGGCTTTCTGACAATCAGTCCAAAGCCCTTATCCCTTTACAAACAGAAGCCCATCCA GAAACAAAGCAAAGAGTATTGACTAACTACATGTTTCCCCAGCAGCCTCGTGGTGATGAAGATTTCCAGTCAGACAGTGACAGCTTTAAC CCTACACTGTGGGAAGAGCAGAGACAACAACGCATGACTGTTGCCTTTGAATTTGAAGACAAAAAAGAAGATGACGAAAATGCTGGGAAA GTTAAGGATCTCTCCTGCCAAGCCCCCTGGGAAAGGGGCCAGCGTGGGATTACTCTCCAACCTGCCAGACTGTCTGGCGATTGCTGCACA CCATGGGCCAGGTGTGATCAGCAGATCCAAGATATGCCCGTCCCCCAGAATGACCCACAGCTGGCATGGGGTTGTATAAGTGGCCTCCAG CAGGAAAGGAGCATGTGTACTCCATTGCCAGTTGCAGCACAATCCACCACTCTTCCCTCTCTAAGTGGCAGACAGGTTGAAATAAACCTA AAACGATATCCAACTCCTTACCCAGAGGATTTAAAGAATATGGTAAAATCTGTTCAAAATTTGGTGGGTAAGCCAAGCCATGGAGTGCGT GTTGAGAATTCAAATCCAACTGCTAACACGGAGCAAACTGTGAAAGAAAAATATGAACACAAGTGGCCGGTAGCCCCAAAGGAGATTACA GTGGAGGATTCTTTTGTTCATCCAGCTAATGAAATGAGGATTGGGGAACTTCACCCTTCATTAGCTGAGACCCCTCTGTACCCACCCAAA CTTGTTCTGCTAGGGAAGGACAAAAAAGAATCAACTGATGAGTCTGAAGTTGACAAAACTCACTGTCTGAATAACAGTGTTTCCTCAGGC ACTTACTCAGACTACTCGCCTTCCCAGGCTTCCTCAGGATCCTCTAATACCCGGGTTAAAGTGGGGTCCTTGCAGACAACAGCTAAAGAT GCAGTACATAATTCTTTGTGGGGTAACAGGATTGCACCATCTTTCCCACAGCCTCTTGATTCAAAGCCATTACTCAGCCAGCGGGAGGCT GTTCCCCCAGGCAATATACCACAGCGTCCTGACCGGCTGCCCATGAGTGATACTTTCACTGACAACTGGACTGATGGCTCGCATTATGAC AACACAGGGTTTGTTGCTGAGGAAACCACAGCCGAGAATGCCAACAGTAATCCTCTCTTAAGTTCGAAATCTAGAAGCACATCTTCGCAT GGACGCAGGCCTTTGATCAGGCAAGACAGGATTGTTGGTGTTCCCCTGGAACTCGAGCAGTCTACACACAGACACACACCAGAAACAGAA GTGCCTCCTTCCAATCCTTGGCAGAATTGGACCAGAACCCCTAGTCCGTTTGAAGACAGGACCGCTTTTCCTTCCAAATTAGAGACAACC CCCACTACCAGCCCATTGCCTGAAAGGAAAGAACATATAAAGGAATCTACTGAAATACCTAGTCCTTTTTCTCCAGGCGTACCATGGGAG TATCATGATTCCAATCCCAACAGGAGTCTTAGTAATGTCTTTTCTCAAATCCACTGCCGCCCGGAATCTTCTAAAGGTGTTATTTCAATT AGCAAAAGCACAGAGAGGCTTTCCCCCCTAATGAAAGATATCAAGTCTAATAAATTCAAAAAGTCACAGAGTATCGATGAGATTGACATT GGTACATATAAGGTGTATAACATACCATTAGAAAACTATGCTTCTGGGAGTGATCACTTAGGAAGCCACGAACGACCGGATAAGATGCTG GGACCAGAGCATGGTATGTCCAGTATGTCTCGAAGCCAGTCAGTCCCAATGCTGGATGATGAGATGCTCACCTACGGAAGTAGTAAGGGG CCACAACAACAAAAAGCTTCTATGACAAAAAAAGTCTATCAGTTTGACCAAAGCTTCAATCCTCAAGGATCAGTGGAAGTGAAAGCCGAA AAGAGGATACCACCCCCTTTTCAACACAATCCCGAGTACGTGCAACAGGCCAGCAAAAACATCGCCAAGGATTTGATTAGTCCTAGAGCT TACAGAGGATACCCACCGATGGAGCAAATGTTTTCATTTTCTCAGCCATCTGTGAATGAGGATGCTGTGGTGAATGCCCAGTTCGCAAGC CAAGGGGCCAGGGCGGGCTTCCTGAGAAGGGCCGACTCCCTGGTGAGCGCCACAGAAATGGCCATGTTTAGAAGGGTCAATGAGCCTCAT GAGCTGCCCCCAACTGATAGGTACGGCAGACCCCCATATAGGGGAGGGCTGGATCGCCAAAGCAGCGTTACAGTGACTGAGTCCCAGTTC CTGAAAAGGAATGGCAGGTATGAAGATGAACACCCTTCATATCAAGAAGTGAAAGCTCAGGCGGGAAGTTTTCCGGTTAAAAACCTTACC CAAAGGAGGCCATTGTCTGCGAGAAGCTACAGTACAGAGAGTTACGGTGCCTCCCAAACCAGGCCAGTTTCAGCTAGGCCTACTATGGCA GCTCTTTTGGAAAAAATACCATCTGACTATAACTTGGGTAACTATGGTGACAAGCCATCAGATAACAGTGATTTAAAGACGAGGCCTACT CCTGTGAAGGGAGAGGAGAGCTGTGGTAAAATGCCTGCAGACTGGAGACAACAGCTGCTTAGACATATAGAAGCTAGACGGTTAGACAGG ACCCCGTCCCAGCAAAGCAACATTTTAGACAATGGACAAGAAGATGTATCTCCTAGTGGCCAATGGAATCCTTATCCACTTGGGAGGCGG GATGTACCTCCGGACACCATTACTAAGAAGGCAGGCAGCCACATCCAGACGTTGATGGGGTCCCAAAGCCTTCAGCATCGCAGCCGGGAG CAGCAGCCGTATGAAGGAAATATAAACAAAGTGACCATCCAGCAATTTCAGTCACCATTGCCTATTCAGATCCCCTCTTCACAGGCCACC CGGGGACCTCAGCCTGGACGGTGCTTAATTCAAACTAAAGGGCAAAGGAGTATGGATGGATATCCAGAGCAGTTTTGTGTGAGAATAGAA AAGAATCCTGGCCTTGGATTTAGTATCAGTGGTGGAATTAGTGGACAAGGAAATCCATTCAAACCTTCTGACAAGGGTATCTTTGTTACT AGGGTTCAGCCTGATGGGCCAGCATCAAACCTACTGCAGCCTGGTGATAAGATCCTTCAGGCAAATGGACACAGTTTTGTACATATGGAA >In-frame_FAF1_ENST00000396153_chr1_51323601_-_LRRC7_ENST00000370958_chr1_70257726_+_465nt ATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGCTT GAACAAAATAATTGGGACTTAGTGCAATTGTTCAACTGTCAAGCTCTACGAAAACTAAGTATTCCTGATAACGACCTTTCAAATCTGCCA ACCACTATTGCTAGTTTAGTTAATCTTAAAGAACTCGACATCAGTAAAAATGGTGTACAAGAATTTCCAGAAAACATAAAGTGCTGTAAG TGTTTAACAATTATTGAAGCCAGTGTCAATCCCATTTCTAAACTACCTGATGGCTTCACACAGCTCCTAAACCTGACCCAGCTCTACCTG AATGACGCCTTTCTTGAATTTCTTCCAGCCAATTTTGGAAGACTTGTCAAATTGCGGATCTTGGAGTTAAGAGAAAATCACTTGAAAACT >In-frame_FAF1_ENST00000396153_chr1_51323601_-_LRRC7_ENST00000035383_chr1_70257726_+_4539nt ATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGCTT GAACAAAATAATTGGGACTTAGTGCAATTGTTCAACTGTCAAGCTCTACGAAAACTAAGTATTCCTGATAACGACCTTTCAAATCTGCCA ACCACTATTGCTAGTTTAGTTAATCTTAAAGAACTCGACATCAGTAAAAATGGTGTACAAGAATTTCCAGAAAACATAAAGTGCTGTAAG TGTTTAACAATTATTGAAGCCAGTGTCAATCCCATTTCTAAACTACCTGATGGCTTCACACAGCTCCTAAACCTGACCCAGCTCTACCTG AATGACGCCTTTCTTGAATTTCTTCCAGCCAATTTTGGAAGACTTGTCAAATTGCGGATCTTGGAGTTAAGAGAAAATCACTTGAAAACT CTACCAAAGTCAATGCACAAACTGGCCCAGTTGGAAAGACTTGACCTAGGCAATAATGAATTCGGTGAGCTGCCTGAAGTTCTGGATCAA ATACAAAATTTGAGGGAGTTATGGATGGATAATAATGCATTACAAGTGTTACCTGGGTCTATAGGGAAGTTAAAGATGTTGGTATACCTG GATATGTCAAAAAACAGAATAGAAACAGTTGACATGGACATTTCTGGATGTGAAGCCCTTGAGGACCTCTTATTGTCATCCAATATGTTG CAACAATTGCCTGATTCTATAGGACTTTTGAAAAAACTAACAACTCTAAAAGTAGATGACAATCAACTTACAATGCTACCCAATACAATT GGAAATTTATCTTTATTAGAAGAATTTGACTGTAGCTGTAATGAACTGGAGTCACTACCTTCTACTATTGGCTACCTTCATAGTCTTCGG ACATTAGCAGTTGATGAGAATTTCCTTCCAGAATTACCCAGAGAAATTGGAAGTTGTAAGAATGTAACAGTCATGTCTCTACGCTCCAAC AAATTAGAATTTCTTCCTGAAGAGATTGGACAGATGCAGAAACTAAGAGTCCTAAATTTGAGTGACAACAGATTGAAGAATTTACCATTC TCATTTACCAAACTTAAAGAGCTTGCAGCTTTGTGGCTTTCTGACAATCAGTCCAAAGCCCTTATCCCTTTACAAACAGAAGCCCATCCA GAAACAAAGCAAAGAGTATTGACTAACTACATGTTTCCCCAGCAGCCTCGTGGTGATGAAGATTTCCAGTCAGACAGTGACAGCTTTAAC CCTACACTGTGGGAAGAGCAGAGACAACAACGCATGACTGTTGCCTTTGAATTTGAAGACAAAAAAGAAGATGACGAAAATGCTGGGAAA GTTAAGGATCTCTCCTGCCAAGCCCCCTGGGAAAGGGGCCAGCGTGGGATTACTCTCCAACCTGCCAGACTGTCTGGCGATTGCTGCACA CCATGGGCCAGGTGTGATCAGCAGATCCAAGATATGCCCGTCCCCCAGAATGACCCACAGCTGGCATGGGGTTGTATAAGTGGCCTCCAG CAGGAAAGGAGCATGTGTACTCCATTGCCAGTTGCAGCACAATCCACCACTCTTCCCTCTCTAAGTGGCAGACAGGTTGAAATAAACCTA AAACGATATCCAACTCCTTACCCAGAGGATTTAAAGAATATGGTAAAATCTGTTCAAAATTTGGTGGGTAAGCCAAGCCATGGAGTGCGT GTTGAGAATTCAAATCCAACTGCTAACACGGAGCAAACTGTGAAAGAAAAATATGAACACAAGTGGCCGGTAGCCCCAAAGGAGATTACA GTGGAGGATTCTTTTGTTCATCCAGCTAATGAAATGAGGATTGGGGAACTTCACCCTTCATTAGCTGAGACCCCTCTGTACCCACCCAAA CTTGTTCTGCTAGGGAAGGACAAAAAAGAATCAACTGATGAGTCTGAAGTTGACAAAACTCACTGTCTGAATAACAGTGTTTCCTCAGGC ACTTACTCAGACTACTCGCCTTCCCAGGCTTCCTCAGGATCCTCTAATACCCGGGTTAAAGTGGGGTCCTTGCAGACAACAGCTAAAGAT GCAGTACATAATTCTTTGTGGGGTAACAGGATTGCACCATCTTTCCCACAGCCTCTTGATTCAAAGCCATTACTCAGCCAGCGGGAGGCT GTTCCCCCAGGCAATATACCACAGCGTCCTGACCGGCTGCCCATGAGTGATACTTTCACTGACAACTGGACTGATGGCTCGCATTATGAC AACACAGGGTTTGTTGCTGAGGAAACCACAGCCGAGAATGCCAACAGTAATCCTCTCTTAAGTTCGAAATCTAGAAGCACATCTTCGCAT GGACGCAGGCCTTTGATCAGGCAAGACAGGATTGTTGGTGTTCCCCTGGAACTCGAGCAGTCTACACACAGACACACACCAGAAACAGAA GTGCCTCCTTCCAATCCTTGGCAGAATTGGACCAGAACCCCTAGTCCGTTTGAAGACAGGACCGCTTTTCCTTCCAAATTAGAGACAACC CCCACTACCAGCCCATTGCCTGAAAGGAAAGAACATATAAAGGAATCTACTGAAATACCTAGTCCTTTTTCTCCAGGCGTACCATGGGAG TATCATGATTCCAATCCCAACAGGAGTCTTAGTAATGTCTTTTCTCAAATCCACTGCCGCCCGGAATCTTCTAAAGGTGTTATTTCAATT AGCAAAAGCACAGAGAGGCTTTCCCCCCTAATGAAAGATATCAAGTCTAATAAATTCAAAAAGTCACAGAGTATCGATGAGATTGACATT GGTACATATAAGGTGTATAACATACCATTAGAAAACTATGCTTCTGGGAGTGATCACTTAGGAAGCCACGAACGACCGGATAAGATGCTG GGACCAGAGCATGGTATGTCCAGTATGTCTCGAAGCCAGTCAGTCCCAATGCTGGATGATGAGATGCTCACCTACGGAAGTAGTAAGGGG CCACAACAACAAAAAGCTTCTATGACAAAAAAAGTCTATCAGTTTGACCAAAGCTTCAATCCTCAAGGATCAGTGGAAGTGAAAGCCGAA AAGAGGATACCACCCCCTTTTCAACACAATCCCGAGTACGTGCAACAGGCCAGCAAAAACATCGCCAAGGATTTGATTAGTCCTAGAGCT TACAGAGGATACCCACCGATGGAGCAAATGTTTTCATTTTCTCAGCCATCTGTGAATGAGGATGCTGTGGTGAATGCCCAGTTCGCAAGC CAAGGGGCCAGGGCGGGCTTCCTGAGAAGGGCCGACTCCCTGGTGAGCGCCACAGAAATGGCCATGTTTAGAAGGGTCAATGAGCCTCAT GAGCTGCCCCCAACTGATAGGTACGGCAGACCCCCATATAGGGGAGGGCTGGATCGCCAAAGCAGCGTTACAGTGACTGAGTCCCAGTTC CTGAAAAGGAATGGCAGGTATGAAGATGAACACCCTTCATATCAAGAAGTGAAAGCTCAGGCGGGAAGTTTTCCGGTTAAAAACCTTACC CAAAGGAGGCCATTGTCTGCGAGAAGCTACAGTACAGAGAGTTACGGTGCCTCCCAAACCAGGCCAGTTTCAGCTAGGCCTACTATGGCA GCTCTTTTGGAAAAAATACCATCTGACTATAACTTGGGTAACTATGGTGACAAGCCATCAGATAACAGTGATTTAAAGACGAGGCCTACT CCTGTGAAGGGAGAGGAGAGCTGTGGTAAAATGCCTGCAGACTGGAGACAACAGCTGCTTAGACATATAGAAGCTAGACGGTTAGACAGG AATGCTGCTTACAAACACAATACAGTTAACCTTGGCATGCTGCCCTATGGAGGTATTTCAGCAATGCATGCAGGCAGAAGCATGACTTTA AACTTGCAGACTAAGTCTAAATTTGATCATCAAGAACTACCTCTTCAGAAAACCCCGTCCCAGCAAAGCAACATTTTAGACAATGGACAA GAAGATGTATCTCCTAGTGGCCAATGGAATCCTTATCCACTTGGGAGGCGGGATGTACCTCCGGACACCATTACTAAGAAGGCAGGCAGC CACATCCAGACGTTGATGGGGTCCCAAAGCCTTCAGCATCGCAGCCGGGAGCAGCAGCCGTATGAAGGAAATATAAACAAAGTGACCATC CAGCAATTTCAGTCACCATTGCCTATTCAGATCCCCTCTTCACAGGCCACCCGGGGACCTCAGCCTGGACGGTGCTTAATTCAAACTAAA GGGCAAAGGAGTATGGATGGATATCCAGAGCAGTTTTGTGTGAGAATAGAAAAGAATCCTGGCCTTGGATTTAGTATCAGTGGTGGAATT AGTGGACAAGGAAATCCATTCAAACCTTCTGACAAGGGTATCTTTGTTACTAGGGTTCAGCCTGATGGGCCAGCATCAAACCTACTGCAG CCTGGTGATAAGATCCTTCAGGCAAATGGACACAGTTTTGTACATATGGAACATGAAAAAGCTGTATTACTACTGAAGAGTTTCCAGAAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_FAF1_ENST00000396153_chr1_51323601_-_LRRC7_ENST00000310961_chr1_70257726_+_6451nt AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGC TTGAACAAAATAATTGGGACTTAGTGCAATTGTTCAACTGTCAAGCTCTACGAAAACTAAGTATTCCTGATAACGACCTTTCAAATCTGC CAACCACTATTGCTAGTTTAGTTAATCTTAAAGAACTCGACATCAGTAAAAATGGTGTACAAGAATTTCCAGAAAACATAAAGTGCTGTA AGTGTTTAACAATTATTGAAGCCAGTGTCAATCCCATTTCTAAACTACCTGATGGCTTCACACAGCTCCTAAACCTGACCCAGCTCTACC TGAATGACGCCTTTCTTGAATTTCTTCCAGCCAATTTTGGAAGACTTGTCAAATTGCGGATCTTGGAGTTAAGAGAAAATCACTTGAAAA CTCTACCAAAGTCAATGCACAAACTGGCCCAGTTGGAAAGACTTGACCTAGGCAATAATGAATTCGGTGAGCTGCCTGAAGTTCTGGATC AAATACAAAATTTGAGGGAGTTATGGATGGATAATAATGCATTACAAGTGTTACCTGGGTCTATAGGGAAGTTAAAGATGTTGGTATACC TGGATATGTCAAAAAACAGAATAGAAACAGTTGACATGGACATTTCTGGATGTGAAGCCCTTGAGGACCTCTTATTGTCATCCAATATGT TGCAACAATTGCCTGATTCTATAGGACTTTTGAAAAAACTAACAACTCTAAAAGTAGATGACAATCAACTTACAATGCTACCCAATACAA TTGGAAATTTATCTTTATTAGAAGAATTTGACTGTAGCTGTAATGAACTGGAGTCACTACCTTCTACTATTGGCTACCTTCATAGTCTTC GGACATTAGCAGTTGATGAGAATTTCCTTCCAGAATTACCCAGAGAAATTGGAAGTTGTAAGAATGTAACAGTCATGTCTCTACGCTCCA ACAAATTAGAATTTCTTCCTGAAGAGATTGGACAGATGCAGAAACTAAGAGTCCTAAATTTGAGTGACAACAGATTGAAGAATTTACCAT TCTCATTTACCAAACTTAAAGAGCTTGCAGCTTTGTGGCTTTCTGACAATCAGTCCAAAGCCCTTATCCCTTTACAAACAGAAGCCCATC CAGAAACAAAGCAAAGAGTATTGACTAACTACATGTTTCCCCAGCAGCCTCGTGGTGATGAAGATTTCCAGTCAGACAGTGACAGCTTTA ACCCTACACTGTGGGAAGAGCAGAGACAACAACGCATGACTGTTGCCTTTGAATTTGAAGACAAAAAAGAAGATGACGAAAATGCTGGGA AAGTTAAGGATCTCTCCTGCCAAGCCCCCTGGGAAAGGGGCCAGCGTGGGATTACTCTCCAACCTGCCAGACTGTCTGGCGATTGCTGCA CACCATGGGCCAGGTGTGATCAGCAGATCCAAGATATGCCCGTCCCCCAGAATGACCCACAGCTGGCATGGGGTTGTATAAGTGGCCTCC AGCAGGAAAGGAGCATGTGTACTCCATTGCCAGTTGCAGCACAATCCACCACTCTTCCCTCTCTAAGTGGCAGACAGGTTGAAATAAACC TAAAACGATATCCAACTCCTTACCCAGAGGATTTAAAGAATATGGTAAAATCTGTTCAAAATTTGGTGGGTAAGCCAAGCCATGGAGTGC GTGTTGAGAATTCAAATCCAACTGCTAACACGGAGCAAACTGTGAAAGAAAAATATGAACACAAGTGGCCGGTAGCCCCAAAGGAGATTA CAGTGGAGGATTCTTTTGTTCATCCAGCTAATGAAATGAGGATTGGGGAACTTCACCCTTCATTAGCTGAGACCCCTCTGTACCCACCCA AACTTGTTCTGCTAGGGAAGGACAAAAAAGAATCAACTGATGAGTCTGAAGTTGACAAAACTCACTGTCTGAATAACAGTGTTTCCTCAG GCACTTACTCAGACTACTCGCCTTCCCAGGCTTCCTCAGGATCCTCTAATACCCGGGTTAAAGTGGGGTCCTTGCAGACAACAGCTAAAG ATGCAGTACATAATTCTTTGTGGGGTAACAGGATTGCACCATCTTTCCCACAGCCTCTTGATTCAAAGCCATTACTCAGCCAGCGGGAGG CTGTTCCCCCAGGCAATATACCACAGCGTCCTGACCGGCTGCCCATGAGTGATACTTTCACTGACAACTGGACTGATGGCTCGCATTATG ACAACACAGGGTTTGTTGCTGAGGAAACCACAGCCGAGAATGCCAACAGTAATCCTCTCTTAAGTTCGAAATCTAGAAGCACATCTTCGC ATGGACGCAGGCCTTTGATCAGGCAAGACAGGATTGTTGGTGTTCCCCTGGAACTCGAGCAGTCTACACACAGACACACACCAGAAACAG AAGTGCCTCCTTCCAATCCTTGGCAGAATTGGACCAGAACCCCTAGTCCGTTTGAAGACAGGACCGCTTTTCCTTCCAAATTAGAGACAA CCCCCACTACCAGCCCATTGCCTGAAAGGAAAGAACATATAAAGGAATCTACTGAAATACCTAGTCCTTTTTCTCCAGGCGTACCATGGG AGTATCATGATTCCAATCCCAACAGGAGTCTTAGTAATGTCTTTTCTCAAATCCACTGCCGCCCGGAATCTTCTAAAGGTGTTATTTCAA TTAGCAAAAGCACAGAGAGGCTTTCCCCCCTAATGAAAGATATCAAGTCTAATAAATTCAAAAAGTCACAGAGTATCGATGAGATTGACA TTGGTACATATAAGGTGTATAACATACCATTAGAAAACTATGCTTCTGGGAGTGATCACTTAGGAAGCCACGAACGACCGGATAAGATGC TGGGACCAGAGCATGGTATGTCCAGTATGTCTCGAAGCCAGTCAGTCCCAATGCTGGATGATGAGATGCTCACCTACGGAAGTAGTAAGG GGCCACAACAACAAAAAGCTTCTATGACAAAAAAAGTCTATCAGTTTGACCAAAGCTTCAATCCTCAAGGATCAGTGGAAGTGAAAGCCG AAAAGAGGATACCACCCCCTTTTCAACACAATCCCGAGTACGTGCAACAGGCCAGCAAAAACATCGCCAAGGATTTGATTAGTCCTAGAG CTTACAGAGGATACCCACCGATGGAGCAAATGTTTTCATTTTCTCAGCCATCTGTGAATGAGGATGCTGTGGTGAATGCCCAGTTCGCAA GCCAAGGGGCCAGGGCGGGCTTCCTGAGAAGGGCCGACTCCCTGGTGAGCGCCACAGAAATGGCCATGTTTAGAAGGGTCAATGAGCCTC ATGAGCTGCCCCCAACTGATAGGTACGGCAGACCCCCATATAGGGGAGGGCTGGATCGCCAAAGCAGCGTTACAGTGACTGAGTCCCAGT TCCTGAAAAGGAATGGCAGGTATGAAGATGAACACCCTTCATATCAAGAAGTGAAAGCTCAGGCGGGAAGTTTTCCGGTTAAAAACCTTA CCCAAAGGAGGCCATTGTCTGCGAGAAGCTACAGTACAGAGAGTTACGGTGCCTCCCAAACCAGGCCAGTTTCAGCTAGGCCTACTATGG CAGCTCTTTTGGAAAAAATACCATCTGACTATAACTTGGGTAACTATGGTGACAAGCCATCAGATAACAGTGATTTAAAGACGAGGCCTA CTCCTGTGAAGGGAGAGGAGAGCTGTGGTAAAATGCCTGCAGACTGGAGACAACAGCTGCTTAGACATATAGAAGCTAGACGGTTAGACA GGACCCCGTCCCAGCAAAGCAACATTTTAGACAATGGACAAGAAGATGTATCTCCTAGTGGCCAATGGAATCCTTATCCACTTGGGAGGC GGGATGTACCTCCGGACACCATTACTAAGAAGGCAGGCAGCCACATCCAGACGTTGATGGGGTCCCAAAGCCTTCAGCATCGCAGCCGGG AGCAGCAGCCGTATGAAGGAAATATAAACAAAGTGACCATCCAGCAATTTCAGTCACCATTGCCTATTCAGATCCCCTCTTCACAGGCCA CCCGGGGACCTCAGCCTGGACGGTGCTTAATTCAAACTAAAGGGCAAAGGAGTATGGATGGATATCCAGAGCAGTTTTGTGTGAGAATAG AAAAGAATCCTGGCCTTGGATTTAGTATCAGTGGTGGAATTAGTGGACAAGGAAATCCATTCAAACCTTCTGACAAGGGTATCTTTGTTA CTAGGGTTCAGCCTGATGGGCCAGCATCAAACCTACTGCAGCCTGGTGATAAGATCCTTCAGGCAAATGGACACAGTTTTGTACATATGG AACATGAAAAAGCTGTATTACTACTGAAGAGTTTCCAGAACACAGTAGACCTAGTTATTCAACGTGAGCTTACTGTCTAAATATTTTTTA TAAATAGTGAAGATACGTCTAGCCAGACCTAATGTTCAAAAATAAATTTATACATAGAAACAAATTTTGCCAATTGCTGGACCAATGGCA AACATTAGTGCCAAATGTATAATACTATATGTTAGCACTGACCATCCTTAAAAAATGTTAACTCTATAAATATGATGTTCATGTGGTTAT GTATTAGTTTTAATTGTCAGCCTCTGGCTGTGCATTGGTGCAGTTTTGTTTCTGTTTTTGTTTTTGTTTTTAATCAAATAAGTTTCTTCT CAAAATGGATTTCATATAATTTCGGAGCACGGAAGCACACACAAGCTCTTTATGAATTCTGCTCTCCATCAGAAACACTGCCTCAAAGTT GTATATGCCTTTATATAGAAAATACAAATATAAAGAATTGTAATTCCCATAAAATATTTCTAGCACAAGGTATATGTTGGCATATATACA AAAAGAATATAGAGAAAAACAATATTTTCATAAACTAAACATCTCAGATAGAGAAAAAATATATCTTAAAATAAGACTTTACTATATTGA ATCTTTTTCAATAAAAATTACATGATAATGCCTTATGAAAGTAACTGTACATATGGTATAAAGTGTTTATATTTGGTTCCATATTCATTT GCTAAATTCTCATGACACAGAGTGAAATATTTCATAAATTAGCCATTTATCTCTGGGACCCAAATAAAAATAGGATGAACTAATTTGTTC AATGCCTTTAGCTAATTACAATACATGCAGAGTTTAGAAACAGACTAAAGGTCATTGTAGTTAAGTCTTTTTCACCACAAATTTAAGCAG TGGATGATGGGTGGCAGGAAAGGTATTGCTTTATTTCTTTCAAGTTCATGTTGATTATAAACTGTAGCCCCTGTGATTTCTTTACTTGTA AATGTGGAATTTATTTGTGTGTTGCTTAATCTAATTTGCTGCTTTTTAAATTATTTAAAACGAATTTTGGAAATTGATAAAATTTATCAT TACGAAAGACTGCTGTTAGAAAGTTATGGTAGGTGATTTTAAATCCTTGGTATTTAAATATGAAACTTCAAATATAATTTCTCAGAGCTG TGGTCTACCTGTATCATTAATTTCAATGGCTGTTTTTCTGGGCAGAAATAGATAAAATACTTTTTTTCCAAAAACAGTTTCAAGGTATGT AAAATCCTGAATGCTTTTTCACTGAAGAGAAAGACAAGCATGGTTAATGTAGAATTATTTACTTTTCCATTGAAACTATTTTCCTGCATA AATGATCAAAATTTATTTTATAATCCTTTAAAATACTTATCTTTCATATTAGTCATTAATTTAATTACAATATTAATTTGAATTTCCAGG ATAATTTCCCGGAGTTGGTTGCATGCATTATCTTTCATAATTTTACATAGTTCTTTTGTTATATAATGAATTTACTTTACATGCTAGTGT TTCAAGTATTGTATGAGGATTTTCACAATAGTATCACTGAATGATGTCACCAGAGCTCTGAGAATAATATTTGTAAGTTAACTGTTTTAT >In-frame_FAF1_ENST00000396153_chr1_51323601_-_LRRC7_ENST00000370958_chr1_70257726_+_2448nt AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGC TTGAACAAAATAATTGGGACTTAGTGCAATTGTTCAACTGTCAAGCTCTACGAAAACTAAGTATTCCTGATAACGACCTTTCAAATCTGC CAACCACTATTGCTAGTTTAGTTAATCTTAAAGAACTCGACATCAGTAAAAATGGTGTACAAGAATTTCCAGAAAACATAAAGTGCTGTA AGTGTTTAACAATTATTGAAGCCAGTGTCAATCCCATTTCTAAACTACCTGATGGCTTCACACAGCTCCTAAACCTGACCCAGCTCTACC TGAATGACGCCTTTCTTGAATTTCTTCCAGCCAATTTTGGAAGACTTGTCAAATTGCGGATCTTGGAGTTAAGAGAAAATCACTTGAAAA CTCTACCAAACATCTGAAGATCCAGAGTGTGCCCCTTGCCCAATCGCCTGAGACTATACAGTGACACCTACAACAGAGGATGTGGAGGGA GCAGCTTTTCGGGCACCAGAAATGGCAGCATCAGGAGCATCAGCACGAATAGACTTTGTAGAGGTAGTTCTCCCAAACTATATTATGAAA CCAAACATTTTTGGTGCGCTACCTGCTGATGGGGGCTGCCTTCTTACTGCCTAGTATCTACAAAATGTTTGGTCTTTGTTAAAGTTTAAC GATGACATTTCTGACTAATATAGAGAGACCTGATTTTTTTCCAAATGTGTTCAGTTGCCATAACTTTCAATGAATATGAAATTTTATCAG TCTCAGAAAAACATTAATACCCATATTTTTATCTAATTGATTTCACTATTTGTTATGTTAAGGTGCTTTTGTGTATAATTTTTGTATATA TTTTTAAATGGGATCAAACTAAGCCATAATTTAAAAGTCATCCTAATGCAGTAAATAAGATAATTTCTCTAGTTTGTTAAATTCTTCAGA GACCGAATATAATTGCTCGTTTTTCTGTCATACTCCCTGATGATGTTCCATTGTGGACTTATTTTGCAAAGTTCCCAGATGGCACAAGTC AAAATATGAAATGCTGATGATTGATTGATTTTATGTATCCTTTCATCTTATGTAATTTAATGTGGAACAGTTATTTTGTAGCTCTAAAAT ACATTTGTTAATTAACCATATTGGCTTTTCATGCAGTTCAATGGCTTATAGCATTTCAATTTGCATAGAAAATGAATCTCTGTAATGATA CTTTTGCTAAATAAATAACAATCGACATAATGGGTTCATTTGCTTTTAACATTTTATACATACAATTTAGAAGTAGGATATATTTCATAT TGAAATTTTGAAAAGCTTGAAATTCAACATACAAGGTCACCATCTTGCTGATGCCTAATGCAGTACAGCAAATTCATTCTTCATCCCATG TTAACTCCTTTTTGGAACAAGTCAAAATACAAATAATTTACAATGATTGTGTTGGAGCTATTGCTTGATTAAATACAATTCAAAGGTTCT TTTTATAAAACAGGTGTGAGCAGGACACATTGCACTTACGGGCTTTTCCTATTTTTTTGGTTCTATTTCATTTTACTGCCTAGGAAAGAA ACATTTTTTTGTAAAACCTATGCTATGGAACTGAAATGTACTTTATTGAATATTTCTATTCTGTTTTATGAATATCAATTATGTGAAATA TATAAATATAAAATTGCCTTAGAATGCCTAACTCTTTGTATAAAACAGATATCTGAAAGTAGATGTTGGTTTTTTGTTCAAATTGTGTAA ATGCTGATTTTTCCATGAGTACTTATGAAGATCTATATGTAAAAATTTTAAGTCTGCTTACTGTGTTTGTACCACCTTGTTCTTAGCTGT GTATACTCTATGCTAATTGACTTCTGTCATTGTCACATATATTGCATATGTCTCTCAAAAATTAAAAGGTATATTGCTATTCTAAAAATA >In-frame_FAF1_ENST00000396153_chr1_51323601_-_LRRC7_ENST00000035383_chr1_70257726_+_5347nt AGGGGCGGAGGCGGCGGCCAGGGAGGAAGCGGAGGAGGCGGAGGCGGCCGCGGCGTTCGCCCGCCCGCTCGCTCGCTCGGTTTCCCCGCC CCCGCCGGGCTTAACGCCGCTGAAGGTATCCGGGTGCGCGCTGTCGCAACCTGCCCTCATCCTGGCCCGCGACTGTAAGACCGGACCCAC ATCCAGACCAATCTTCCTGTCCGGGCTGCTGCGACGCGGGCTCCGCAGGTTGCAGGCGGGCGGCCGGGGCGCCTGAAGGTTACCGAGTGC ATGAGCGCCTAGCGCTTCCCGCGCTGCCCCGCCCGCTGGCCCGCCGACCCGCCCGCCGGCTCGCCCGCCAGCCCCTCGGCGCCCGGCGGC GGCGGCGGCGGTGGCGGCGACGGTCGCAGGAGGTGCCGTCTGCCTCCCAGGTGCGCGCTTCGCTCCCGGAGCCGCGGAACTCGGCGGCCG CCATGGCGTCCAACATGGACCGGGAGATGATCCTGGCGGATTTTCAGGCATGTACTGGCATTGAAAACATTGACGAAGCTATTACATTGC TTGAACAAAATAATTGGGACTTAGTGCAATTGTTCAACTGTCAAGCTCTACGAAAACTAAGTATTCCTGATAACGACCTTTCAAATCTGC CAACCACTATTGCTAGTTTAGTTAATCTTAAAGAACTCGACATCAGTAAAAATGGTGTACAAGAATTTCCAGAAAACATAAAGTGCTGTA AGTGTTTAACAATTATTGAAGCCAGTGTCAATCCCATTTCTAAACTACCTGATGGCTTCACACAGCTCCTAAACCTGACCCAGCTCTACC TGAATGACGCCTTTCTTGAATTTCTTCCAGCCAATTTTGGAAGACTTGTCAAATTGCGGATCTTGGAGTTAAGAGAAAATCACTTGAAAA CTCTACCAAAGTCAATGCACAAACTGGCCCAGTTGGAAAGACTTGACCTAGGCAATAATGAATTCGGTGAGCTGCCTGAAGTTCTGGATC AAATACAAAATTTGAGGGAGTTATGGATGGATAATAATGCATTACAAGTGTTACCTGGGTCTATAGGGAAGTTAAAGATGTTGGTATACC TGGATATGTCAAAAAACAGAATAGAAACAGTTGACATGGACATTTCTGGATGTGAAGCCCTTGAGGACCTCTTATTGTCATCCAATATGT TGCAACAATTGCCTGATTCTATAGGACTTTTGAAAAAACTAACAACTCTAAAAGTAGATGACAATCAACTTACAATGCTACCCAATACAA TTGGAAATTTATCTTTATTAGAAGAATTTGACTGTAGCTGTAATGAACTGGAGTCACTACCTTCTACTATTGGCTACCTTCATAGTCTTC GGACATTAGCAGTTGATGAGAATTTCCTTCCAGAATTACCCAGAGAAATTGGAAGTTGTAAGAATGTAACAGTCATGTCTCTACGCTCCA ACAAATTAGAATTTCTTCCTGAAGAGATTGGACAGATGCAGAAACTAAGAGTCCTAAATTTGAGTGACAACAGATTGAAGAATTTACCAT TCTCATTTACCAAACTTAAAGAGCTTGCAGCTTTGTGGCTTTCTGACAATCAGTCCAAAGCCCTTATCCCTTTACAAACAGAAGCCCATC CAGAAACAAAGCAAAGAGTATTGACTAACTACATGTTTCCCCAGCAGCCTCGTGGTGATGAAGATTTCCAGTCAGACAGTGACAGCTTTA ACCCTACACTGTGGGAAGAGCAGAGACAACAACGCATGACTGTTGCCTTTGAATTTGAAGACAAAAAAGAAGATGACGAAAATGCTGGGA AAGTTAAGGATCTCTCCTGCCAAGCCCCCTGGGAAAGGGGCCAGCGTGGGATTACTCTCCAACCTGCCAGACTGTCTGGCGATTGCTGCA CACCATGGGCCAGGTGTGATCAGCAGATCCAAGATATGCCCGTCCCCCAGAATGACCCACAGCTGGCATGGGGTTGTATAAGTGGCCTCC AGCAGGAAAGGAGCATGTGTACTCCATTGCCAGTTGCAGCACAATCCACCACTCTTCCCTCTCTAAGTGGCAGACAGGTTGAAATAAACC TAAAACGATATCCAACTCCTTACCCAGAGGATTTAAAGAATATGGTAAAATCTGTTCAAAATTTGGTGGGTAAGCCAAGCCATGGAGTGC GTGTTGAGAATTCAAATCCAACTGCTAACACGGAGCAAACTGTGAAAGAAAAATATGAACACAAGTGGCCGGTAGCCCCAAAGGAGATTA CAGTGGAGGATTCTTTTGTTCATCCAGCTAATGAAATGAGGATTGGGGAACTTCACCCTTCATTAGCTGAGACCCCTCTGTACCCACCCA AACTTGTTCTGCTAGGGAAGGACAAAAAAGAATCAACTGATGAGTCTGAAGTTGACAAAACTCACTGTCTGAATAACAGTGTTTCCTCAG GCACTTACTCAGACTACTCGCCTTCCCAGGCTTCCTCAGGATCCTCTAATACCCGGGTTAAAGTGGGGTCCTTGCAGACAACAGCTAAAG ATGCAGTACATAATTCTTTGTGGGGTAACAGGATTGCACCATCTTTCCCACAGCCTCTTGATTCAAAGCCATTACTCAGCCAGCGGGAGG CTGTTCCCCCAGGCAATATACCACAGCGTCCTGACCGGCTGCCCATGAGTGATACTTTCACTGACAACTGGACTGATGGCTCGCATTATG ACAACACAGGGTTTGTTGCTGAGGAAACCACAGCCGAGAATGCCAACAGTAATCCTCTCTTAAGTTCGAAATCTAGAAGCACATCTTCGC ATGGACGCAGGCCTTTGATCAGGCAAGACAGGATTGTTGGTGTTCCCCTGGAACTCGAGCAGTCTACACACAGACACACACCAGAAACAG AAGTGCCTCCTTCCAATCCTTGGCAGAATTGGACCAGAACCCCTAGTCCGTTTGAAGACAGGACCGCTTTTCCTTCCAAATTAGAGACAA CCCCCACTACCAGCCCATTGCCTGAAAGGAAAGAACATATAAAGGAATCTACTGAAATACCTAGTCCTTTTTCTCCAGGCGTACCATGGG AGTATCATGATTCCAATCCCAACAGGAGTCTTAGTAATGTCTTTTCTCAAATCCACTGCCGCCCGGAATCTTCTAAAGGTGTTATTTCAA TTAGCAAAAGCACAGAGAGGCTTTCCCCCCTAATGAAAGATATCAAGTCTAATAAATTCAAAAAGTCACAGAGTATCGATGAGATTGACA TTGGTACATATAAGGTGTATAACATACCATTAGAAAACTATGCTTCTGGGAGTGATCACTTAGGAAGCCACGAACGACCGGATAAGATGC TGGGACCAGAGCATGGTATGTCCAGTATGTCTCGAAGCCAGTCAGTCCCAATGCTGGATGATGAGATGCTCACCTACGGAAGTAGTAAGG GGCCACAACAACAAAAAGCTTCTATGACAAAAAAAGTCTATCAGTTTGACCAAAGCTTCAATCCTCAAGGATCAGTGGAAGTGAAAGCCG AAAAGAGGATACCACCCCCTTTTCAACACAATCCCGAGTACGTGCAACAGGCCAGCAAAAACATCGCCAAGGATTTGATTAGTCCTAGAG CTTACAGAGGATACCCACCGATGGAGCAAATGTTTTCATTTTCTCAGCCATCTGTGAATGAGGATGCTGTGGTGAATGCCCAGTTCGCAA GCCAAGGGGCCAGGGCGGGCTTCCTGAGAAGGGCCGACTCCCTGGTGAGCGCCACAGAAATGGCCATGTTTAGAAGGGTCAATGAGCCTC ATGAGCTGCCCCCAACTGATAGGTACGGCAGACCCCCATATAGGGGAGGGCTGGATCGCCAAAGCAGCGTTACAGTGACTGAGTCCCAGT TCCTGAAAAGGAATGGCAGGTATGAAGATGAACACCCTTCATATCAAGAAGTGAAAGCTCAGGCGGGAAGTTTTCCGGTTAAAAACCTTA CCCAAAGGAGGCCATTGTCTGCGAGAAGCTACAGTACAGAGAGTTACGGTGCCTCCCAAACCAGGCCAGTTTCAGCTAGGCCTACTATGG CAGCTCTTTTGGAAAAAATACCATCTGACTATAACTTGGGTAACTATGGTGACAAGCCATCAGATAACAGTGATTTAAAGACGAGGCCTA CTCCTGTGAAGGGAGAGGAGAGCTGTGGTAAAATGCCTGCAGACTGGAGACAACAGCTGCTTAGACATATAGAAGCTAGACGGTTAGACA GGAATGCTGCTTACAAACACAATACAGTTAACCTTGGCATGCTGCCCTATGGAGGTATTTCAGCAATGCATGCAGGCAGAAGCATGACTT TAAACTTGCAGACTAAGTCTAAATTTGATCATCAAGAACTACCTCTTCAGAAAACCCCGTCCCAGCAAAGCAACATTTTAGACAATGGAC AAGAAGATGTATCTCCTAGTGGCCAATGGAATCCTTATCCACTTGGGAGGCGGGATGTACCTCCGGACACCATTACTAAGAAGGCAGGCA GCCACATCCAGACGTTGATGGGGTCCCAAAGCCTTCAGCATCGCAGCCGGGAGCAGCAGCCGTATGAAGGAAATATAAACAAAGTGACCA TCCAGCAATTTCAGTCACCATTGCCTATTCAGATCCCCTCTTCACAGGCCACCCGGGGACCTCAGCCTGGACGGTGCTTAATTCAAACTA AAGGGCAAAGGAGTATGGATGGATATCCAGAGCAGTTTTGTGTGAGAATAGAAAAGAATCCTGGCCTTGGATTTAGTATCAGTGGTGGAA TTAGTGGACAAGGAAATCCATTCAAACCTTCTGACAAGGGTATCTTTGTTACTAGGGTTCAGCCTGATGGGCCAGCATCAAACCTACTGC AGCCTGGTGATAAGATCCTTCAGGCAAATGGACACAGTTTTGTACATATGGAACATGAAAAAGCTGTATTACTACTGAAGAGTTTCCAGA ACACAGTAGACCTAGTTATTCAACGTGAGCTTACTGTCTAAATATTTTTTATAAATAGTGAAGATACGTCTAGCCAGACCTAATGTTCAA AAATAAATTTATACATAGAAACAAATTTTGCCAATTGCTGGACCAATGGCAAACATTAGTGCCAAATGTATAATACTATATGTTAGCACT GACCATCCTTAAAAAATGTTAACTCTATAAATATGATGTTCATGTGGTTATGTATTAGTTTTAATTGTCAGCCTCTGGCTGTGCATTGGT GCAGTTTTGTTTCTGTTTTTGTTTTTGTTTTTAATCAAATAAGTTTCTTCTCAAAATGGATTTCATATAATTTCGGAGCACGGAAGCACA |
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FusionGenePPI for FAF1_LRRC7 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| FAF1 | ASCC2, FAS, CSNK2B, G3BP1, RAE1, CASP8, CTNNB1, VCP, NPLOC4, UFD1L, CUL1, CUL2, CUL3, UBR1, HIF1A, ALPP, VCPIP1, SKP1, FBXW11, KLHL22, KBTBD7, WDR26, AMFR, UBR2, UBR4, PJA2, CDC73, TAF1D, RAP1B, UROD, TK1, ANXA1, DNAJB11, CDKN1A, TNNT1, SIRT6, HSD17B10, RCC1, NR1H2, ANXA7, TSC22D1, NR4A1, ITGB1BP1, IGF2, RAD23A, BTRC, NGLY1, UBC, HSPA4, RELA, HSPA8, FADD, IKBKB, NLRP3, NLRP2, NLRP7, NLRP12, NUDT21, SKIL, CARM1, CARS, FAM114A1, FARSB, GART, HIRIP3, HIST1H4A, HSPH1, ILK, PLOD2, PPM1G, PPP2R5C, PRMT3, PUF60, RANBP3, RPL24, SAMHD1, SEC23A, SET, SF1, SWAP70, TLN1, TROVE2, UGP2, XPO7, VAPA, VAPB, UBL4A, ASNA1, GET4, BAG6, RPN2, DDOST, FAF1, CD40, MAGIX, TCEAL1, CBX3, DNAJA1, ZC3H15, NTRK1, RAP1A, CDT1, IPO5, WDR24, YTHDF1, CDC5L, KCTD10, YTHDF3, WDR59, MMAB, NUP98, MYCBP2, USP11, NSFL1C, UBXN7, UBXN1, ASPSCR1, HSPA2, MIOS, UBXN6, BTBD9, KCTD13, TNFAIP1, UBXN2B, BHLHA15, CHCHD10, CLEC3A, PRCC, TRIM25, XIAP | LRRC7 | CNKSR2, SSSCA1, DLG4, CTNND2, CDH2, BAI1, CUL3, NQO2, HOMEZ, CDH1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for FAF1_LRRC7 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FAF1_LRRC7 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | LRRC7 | C0236736 | Cocaine-Related Disorders | 1 | CTD_human |
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