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Center for Computational Systems Medicine
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FusionGeneSummary

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Fusion gene ID: 12231

FusionGeneSummary for EWSR1_ETV4

check button Fusion gene summary
Fusion gene informationFusion gene name: EWSR1_ETV4
Fusion gene ID: 12231
HgeneTgene
Gene symbol

EWSR1

ETV4

Gene ID

2130

2118

Gene nameEWS RNA binding protein 1ETS variant 4
SynonymsEWS|EWS-FLI1|bK984G1.4E1A-F|E1AF|PEA3|PEAS3
Cytomap

22q12.2

17q21.31

Type of geneprotein-codingprotein-coding
DescriptionRNA-binding protein EWSEWS RNA-binding protein variant 6Ewing sarcoma breakpoint region 1Ewings sarcoma EWS-Fli1 (type 1) oncogeneETS translocation variant 4EWS protein/E1A enhancer binding protein chimeraadenovirus E1A enhancer-binding proteinets variant gene 4 (E1A enhancer-binding protein, E1AF)polyomavirus enhancer activator 3 homolog
Modification date2018052720180523
UniProtAcc

Q01844

P43268

Ensembl transtripts involved in fusion geneENST00000332050, ENST00000397938, 
ENST00000406548, ENST00000331029, 
ENST00000414183, ENST00000333395, 
ENST00000332035, 
ENST00000319349, 
ENST00000393664, ENST00000538265, 
ENST00000545954, ENST00000545089, 
ENST00000591713, ENST00000586826, 
Fusion gene scores* DoF score17 X 31 X 5=26359 X 8 X 3=216
# samples 5318
** MAII scorelog2(53/2635*10)=-2.31373869707402
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(18/216*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EWSR1 [Title/Abstract] AND ETV4 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
Transcription factor involved fusion gene, inframe and retained DNA-binding domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneETV4

GO:0045944

positive regulation of transcription by RNA polymerase II

24983502


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1U35622EWSR1chr22

29683123

+ETV4chr17

41607549

-
ChiTaRS3.1AB005538EWSR1chr22

29684696

+ETV4chr17

41609377

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000332050ENST00000319349EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000332050ENST00000393664EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000332050ENST00000538265EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000332050ENST00000545954EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000332050ENST00000545089EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000332050ENST00000591713EWSR1chr22

29683123

+ETV4chr17

41607549

-
5CDS-5UTRENST00000332050ENST00000586826EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000397938ENST00000319349EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000397938ENST00000393664EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000397938ENST00000538265EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000397938ENST00000545954EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000397938ENST00000545089EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000397938ENST00000591713EWSR1chr22

29683123

+ETV4chr17

41607549

-
5CDS-5UTRENST00000397938ENST00000586826EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000406548ENST00000319349EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000406548ENST00000393664EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000406548ENST00000538265EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000406548ENST00000545954EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000406548ENST00000545089EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000406548ENST00000591713EWSR1chr22

29683123

+ETV4chr17

41607549

-
5CDS-5UTRENST00000406548ENST00000586826EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000331029ENST00000319349EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000331029ENST00000393664EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000331029ENST00000538265EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000331029ENST00000545954EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000331029ENST00000545089EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000331029ENST00000591713EWSR1chr22

29683123

+ETV4chr17

41607549

-
5CDS-5UTRENST00000331029ENST00000586826EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000414183ENST00000319349EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000414183ENST00000393664EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000414183ENST00000538265EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000414183ENST00000545954EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000414183ENST00000545089EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000414183ENST00000591713EWSR1chr22

29683123

+ETV4chr17

41607549

-
5CDS-5UTRENST00000414183ENST00000586826EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000333395ENST00000319349EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000333395ENST00000393664EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000333395ENST00000538265EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000333395ENST00000545954EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000333395ENST00000545089EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000333395ENST00000591713EWSR1chr22

29683123

+ETV4chr17

41607549

-
5CDS-5UTRENST00000333395ENST00000586826EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000332035ENST00000319349EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000332035ENST00000393664EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000332035ENST00000538265EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000332035ENST00000545954EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000332035ENST00000545089EWSR1chr22

29683123

+ETV4chr17

41607549

-
In-frameENST00000332035ENST00000591713EWSR1chr22

29683123

+ETV4chr17

41607549

-
5CDS-5UTRENST00000332035ENST00000586826EWSR1chr22

29683123

+ETV4chr17

41607549

-
intron-intronENST00000332050ENST00000319349EWSR1chr22

29684696

+ETV4chr17

41609377

-
intron-intronENST00000332050ENST00000393664EWSR1chr22

29684696

+ETV4chr17

41609377

-
intron-intronENST00000332050ENST00000538265EWSR1chr22

29684696

+ETV4chr17

41609377

-
intron-intronENST00000332050ENST00000545954EWSR1chr22

29684696

+ETV4chr17

41609377

-
intron-intronENST00000332050ENST00000545089EWSR1chr22

29684696

+ETV4chr17

41609377

-
intron-intronENST00000332050ENST00000591713EWSR1chr22

29684696

+ETV4chr17

41609377

-
intron-intronENST00000332050ENST00000586826EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000397938ENST00000319349EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000397938ENST00000393664EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000397938ENST00000538265EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000397938ENST00000545954EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000397938ENST00000545089EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000397938ENST00000591713EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000397938ENST00000586826EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000406548ENST00000319349EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000406548ENST00000393664EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000406548ENST00000538265EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000406548ENST00000545954EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000406548ENST00000545089EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000406548ENST00000591713EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000406548ENST00000586826EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000331029ENST00000319349EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000331029ENST00000393664EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000331029ENST00000538265EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000331029ENST00000545954EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000331029ENST00000545089EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000331029ENST00000591713EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000331029ENST00000586826EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000414183ENST00000319349EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000414183ENST00000393664EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000414183ENST00000538265EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000414183ENST00000545954EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000414183ENST00000545089EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000414183ENST00000591713EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000414183ENST00000586826EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000333395ENST00000319349EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000333395ENST00000393664EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000333395ENST00000538265EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000333395ENST00000545954EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000333395ENST00000545089EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000333395ENST00000591713EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000333395ENST00000586826EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000332035ENST00000319349EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000332035ENST00000393664EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000332035ENST00000538265EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000332035ENST00000545954EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000332035ENST00000545089EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000332035ENST00000591713EWSR1chr22

29684696

+ETV4chr17

41609377

-
5CDS-intronENST00000332035ENST00000586826EWSR1chr22

29684696

+ETV4chr17

41609377

-

Top

FusionProtFeatures for EWSR1_ETV4


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EWSR1

Q01844

ETV4

P43268

Might normally function as a transcriptional repressor.EWS-fusion-proteins (EFPS) may play a role in the tumorigenicprocess. They may disturb gene expression by mimicking, orinterfering with the normal function of CTD-POLII within thetranscription initiation complex. They may also contribute to anaberrant activation of the fusion protein target genes. Transcriptional activator that binds to the enhancer ofthe adenovirus E1A gene; the core-binding sequence is5'[AC]GGA[AT]GT-3'. {ECO:0000269|PubMed:19307308}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616111_116208601RepeatNote=12
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616117_125208601RepeatNote=13
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616126_156208601RepeatNote=14
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616157_163208601RepeatNote=15
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616164_170208601RepeatNote=16
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616171_177208601RepeatNote=17
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616178_188208601RepeatNote=18
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+61617_27208601RepeatNote=2
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616189_193208601RepeatNote=19
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616194_201208601RepeatNote=20
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616202_206208601RepeatNote=21
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+61628_34208601RepeatNote=3
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+61635_42208601RepeatNote=4
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+61643_50208601RepeatNote=5
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+61651_59208601RepeatNote=6
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+61660_68208601RepeatNote=7
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+61669_75208601RepeatNote=8
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+61676_84208601RepeatNote=9
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+61685_91208601RepeatNote=10
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+6168_16208601RepeatNote=1
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+61692_110208601RepeatNote=11
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79111_116264355RepeatNote=12
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79117_125264355RepeatNote=13
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79126_156264355RepeatNote=14
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79157_163264355RepeatNote=15
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79164_170264355RepeatNote=16
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79171_177264355RepeatNote=17
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79178_188264355RepeatNote=18
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+7917_27264355RepeatNote=2
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79189_193264355RepeatNote=19
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79194_201264355RepeatNote=20
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79202_206264355RepeatNote=21
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79207_212264355RepeatNote=22
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79213_218264355RepeatNote=23
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79219_224264355RepeatNote=24
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79225_230264355RepeatNote=25
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79231_238264355RepeatNote=26
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79239_245264355RepeatNote=27
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79246_252264355RepeatNote=28
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79253_259264355RepeatNote=29
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+7928_34264355RepeatNote=3
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+7935_42264355RepeatNote=4
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+7943_50264355RepeatNote=5
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+7951_59264355RepeatNote=6
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+7960_68264355RepeatNote=7
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+7969_75264355RepeatNote=8
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+7976_84264355RepeatNote=9
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+7985_91264355RepeatNote=10
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+798_16264355RepeatNote=1
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+7992_110264355RepeatNote=11
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717111_116264657RepeatNote=12
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717117_125264657RepeatNote=13
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717126_156264657RepeatNote=14
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717157_163264657RepeatNote=15
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717164_170264657RepeatNote=16
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717171_177264657RepeatNote=17
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717178_188264657RepeatNote=18
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+71717_27264657RepeatNote=2
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717189_193264657RepeatNote=19
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717194_201264657RepeatNote=20
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717202_206264657RepeatNote=21
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717207_212264657RepeatNote=22
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717213_218264657RepeatNote=23
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717219_224264657RepeatNote=24
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717225_230264657RepeatNote=25
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717231_238264657RepeatNote=26
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717239_245264657RepeatNote=27
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717246_252264657RepeatNote=28
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717253_259264657RepeatNote=29
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+71728_34264657RepeatNote=3
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+71735_42264657RepeatNote=4
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+71743_50264657RepeatNote=5
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+71751_59264657RepeatNote=6
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+71760_68264657RepeatNote=7
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+71769_75264657RepeatNote=8
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+71776_84264657RepeatNote=9
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+71785_91264657RepeatNote=10
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+7178_16264657RepeatNote=1
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+71792_110264657RepeatNote=11
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717111_116264656RepeatNote=12
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717117_125264656RepeatNote=13
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717126_156264656RepeatNote=14
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717157_163264656RepeatNote=15
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717164_170264656RepeatNote=16
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717171_177264656RepeatNote=17
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717178_188264656RepeatNote=18
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+71717_27264656RepeatNote=2
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717189_193264656RepeatNote=19
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717194_201264656RepeatNote=20
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717202_206264656RepeatNote=21
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717207_212264656RepeatNote=22
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717213_218264656RepeatNote=23
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717219_224264656RepeatNote=24
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717225_230264656RepeatNote=25
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717231_238264656RepeatNote=26
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717239_245264656RepeatNote=27
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717246_252264656RepeatNote=28
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717253_259264656RepeatNote=29
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+71728_34264656RepeatNote=3
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+71735_42264656RepeatNote=4
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+71743_50264656RepeatNote=5
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+71751_59264656RepeatNote=6
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+71760_68264656RepeatNote=7
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+71769_75264656RepeatNote=8
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+71776_84264656RepeatNote=9
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+71785_91264656RepeatNote=10
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+7178_16264656RepeatNote=1
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+71792_110264656RepeatNote=11
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818111_116270662RepeatNote=12
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818117_125270662RepeatNote=13
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818126_156270662RepeatNote=14
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818157_163270662RepeatNote=15
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818164_170270662RepeatNote=16
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818171_177270662RepeatNote=17
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818178_188270662RepeatNote=18
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+81817_27270662RepeatNote=2
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818189_193270662RepeatNote=19
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818194_201270662RepeatNote=20
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818202_206270662RepeatNote=21
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818207_212270662RepeatNote=22
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818213_218270662RepeatNote=23
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818219_224270662RepeatNote=24
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818225_230270662RepeatNote=25
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818231_238270662RepeatNote=26
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818239_245270662RepeatNote=27
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818246_252270662RepeatNote=28
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818253_259270662RepeatNote=29
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+81828_34270662RepeatNote=3
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+81835_42270662RepeatNote=4
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+81843_50270662RepeatNote=5
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+81851_59270662RepeatNote=6
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+81860_68270662RepeatNote=7
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+81869_75270662RepeatNote=8
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+81876_84270662RepeatNote=9
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+81885_91270662RepeatNote=10
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+8188_16270662RepeatNote=1
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+81892_110270662RepeatNote=11
TgeneETV4chr22:29683123chr17:41607549ENST00000319349-713341_421270485DNA bindingETS
TgeneETV4chr22:29683123chr17:41607549ENST00000393664-612341_421270485DNA bindingETS
TgeneETV4chr22:29683123chr17:41607549ENST00000538265-612341_421231446DNA bindingETS
TgeneETV4chr22:29683123chr17:41607549ENST00000545954-612341_421231446DNA bindingETS
TgeneETV4chr22:29683123chr17:41607549ENST00000591713-713341_421270485DNA bindingETS

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616300_340208601Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616454_513208601Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616559_640208601Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79300_340264355Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79454_513264355Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79559_640264355Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717300_340264657Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717454_513264657Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717559_640264657Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717300_340264656Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717454_513264656Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717559_640264656Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818300_340270662Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818454_513270662Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818559_640270662Compositional biasNote=Arg/Gly/Pro-rich
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616256_285208601DomainNote=IQ
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616361_447208601DomainRRM
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79256_285264355DomainNote=IQ
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79361_447264355DomainRRM
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717256_285264657DomainNote=IQ
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717361_447264657DomainRRM
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717256_285264656DomainNote=IQ
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717361_447264656DomainRRM
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818256_285270662DomainNote=IQ
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818361_447270662DomainRRM
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616639_656208601MotifNuclear localization signal
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79639_656264355MotifNuclear localization signal
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717639_656264657MotifNuclear localization signal
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717639_656264656MotifNuclear localization signal
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818639_656270662MotifNuclear localization signal
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+6161_285208601RegionNote=EAD (Gln/Pro/Thr-rich)
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+6168_285208601RegionNote=31 X approximate tandem repeats
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+791_285264355RegionNote=EAD (Gln/Pro/Thr-rich)
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+798_285264355RegionNote=31 X approximate tandem repeats
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+7171_285264657RegionNote=EAD (Gln/Pro/Thr-rich)
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+7178_285264657RegionNote=31 X approximate tandem repeats
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+7171_285264656RegionNote=EAD (Gln/Pro/Thr-rich)
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+7178_285264656RegionNote=31 X approximate tandem repeats
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+8181_285270662RegionNote=EAD (Gln/Pro/Thr-rich)
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+8188_285270662RegionNote=31 X approximate tandem repeats
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616207_212208601RepeatNote=22
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616213_218208601RepeatNote=23
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616219_224208601RepeatNote=24
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616225_230208601RepeatNote=25
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616231_238208601RepeatNote=26
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616239_245208601RepeatNote=27
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616246_252208601RepeatNote=28
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616253_259208601RepeatNote=29
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616260_276208601RepeatNote=30
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616277_285208601RepeatNote=31
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79260_276264355RepeatNote=30
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79277_285264355RepeatNote=31
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717260_276264657RepeatNote=30
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717277_285264657RepeatNote=31
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717260_276264656RepeatNote=30
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717277_285264656RepeatNote=31
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818260_276270662RepeatNote=30
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818277_285270662RepeatNote=31
HgeneEWSR1chr22:29683123chr17:41607549ENST00000332035+616518_549208601Zinc fingerRanBP2-type
HgeneEWSR1chr22:29683123chr17:41607549ENST00000333395+79518_549264355Zinc fingerRanBP2-type
HgeneEWSR1chr22:29683123chr17:41607549ENST00000397938+717518_549264657Zinc fingerRanBP2-type
HgeneEWSR1chr22:29683123chr17:41607549ENST00000406548+717518_549264656Zinc fingerRanBP2-type
HgeneEWSR1chr22:29683123chr17:41607549ENST00000414183+818518_549270662Zinc fingerRanBP2-type
TgeneETV4chr22:29683123chr17:41607549ENST00000319349-713148_244270485Compositional biasNote=Gln-rich
TgeneETV4chr22:29683123chr17:41607549ENST00000319349-71349_75270485Compositional biasNote=Asp/Glu-rich (acidic)
TgeneETV4chr22:29683123chr17:41607549ENST00000393664-612148_244270485Compositional biasNote=Gln-rich
TgeneETV4chr22:29683123chr17:41607549ENST00000393664-61249_75270485Compositional biasNote=Asp/Glu-rich (acidic)
TgeneETV4chr22:29683123chr17:41607549ENST00000538265-612148_244231446Compositional biasNote=Gln-rich
TgeneETV4chr22:29683123chr17:41607549ENST00000538265-61249_75231446Compositional biasNote=Asp/Glu-rich (acidic)
TgeneETV4chr22:29683123chr17:41607549ENST00000545954-612148_244231446Compositional biasNote=Gln-rich
TgeneETV4chr22:29683123chr17:41607549ENST00000545954-61249_75231446Compositional biasNote=Asp/Glu-rich (acidic)
TgeneETV4chr22:29683123chr17:41607549ENST00000591713-713148_244270485Compositional biasNote=Gln-rich
TgeneETV4chr22:29683123chr17:41607549ENST00000591713-71349_75270485Compositional biasNote=Asp/Glu-rich (acidic)


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FusionGeneSequence for EWSR1_ETV4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for EWSR1_ETV4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
EWSR1PRTFDC1, ZDHHC3, MSC, SLC22A24, MYO1F, KXD1, KHDRBS2, DNAJB3, FASN, NLE1, MNS1, PRUNE2, WWP2, NDUFB1, BNIP3L, NSUN4, KRR1, WWP1, RMND5B, SLC1A1, RASL11B, DFFA, WDR37, RPS15A, CPSF6, C11orf16, YY1AP1, RNF183, MTCP1, TULP2, RBPMS, KEL, MYOZ2, FAM131C, HMGA1, NPPB, HERPUD1, CD177, RPL31, VPS72, ACTL6A, RAD23A, MAGEA11, CFDP1, DMRTB1, CXADR, ZNF165, SSBP2, TPGS2, RAB37, CETP, NDUFV1, DYNLL2, NBPF3, CEACAM5, GPBP1L1, SERP2, GNPDA1, C19orf57, ELAVL3, ELAVL4, LILRA3, BAD, CCDC7, MRPS18B, CUEDC2, CNST, TSPAN3, CCDC91, TRIM37, NINL, NTNG2, CPSF7, PGLS, EPT1, MYL6, SMAD4, TMSB4Y, TRPV5, MVK, MAPK1IP1L, MDFI, MTMR9, PLSCR1, RALYL, PDHX, C10orf12, RHOXF2, MATK, SALL2, AGT, KCNMB1, SUV39H2, SMNDC1, ARHGDIA, PUF60, GSK3B, ILK, CD2BP2, BARD1, CREBBP, BTK, SF1, SNRPC, ELK1, PTK2B, CALM1, POU4F1, EZH2, IRF3, TONSL, RFX3, HLTF, SUPT4H1, ZNF184, HIST1H2BN, BLZF1, HDAC3, FXR2, HMGN4, POLR3A, ECD, ZBTB1, SCMH1, SUZ12, E2F8, TRIM5, ZNF383, DHX9, SMN1, PCM1, RAD21, NDRG1, CEBPA, ELAVL1, SIRT7, HNRNPA1, TSG101, TP53, POLR2A, YBX1, TDRD3, CUL3, CUL4A, CUL4B, CUL5, CUL2, CUL1, COPS5, COPS6, DCUN1D1, CAND1, NEDD8, KCND3, ATN1, ATXN3, ERCC5, HBP1, HSPA2, PCBP1, USP7, SRSF5, TMEM126A, SAP30BP, GORASP2, MBD3, MRPS9, HAX1, SFXN1, ITGA5, TCIRG1, RNF168, GEMIN5, HAS1, MTCH1, NDUFA5, MCAT, MRPL57, HDAC2, ESR1, FN1, VCAM1, ITGA4, CD81, PRMT1, SF3B4, EP300, PRRC2A, EWSR1, FUS, ITGB5, NONO, TRAF3, HNRNPUL1, EPAS1, CHERP, CDK12, ITCH, WBP4, RPA3, RPA2, RPA1, HSPA5, RIOK2, TRAF1, TRAF2, SEC24D, TFG, SEC24A, SSBP3, PRR13, ATPAF2, PEF1, JUN, CUL7, OBSL1, CCDC8, RNF2, BMI1, EGFR, ABL1, SRPK1, ABCE1, PRMT8, RPS6KB2, ACAA2, ACAT1, EIF4H, ANXA2, HIP1R, PICALM, POR, NTRK1, SCARNA22, NPM1, KRT2, PRDX2, S100A9, YWHAZ, DDX17, PCLO, ANXA6, SEC24C, GIPC1, CSRP2, FHL1, HNRNPA3, CTTN, MARCKSL1, PARP1, SERPINB3, CCDC50, KIF2A, KRT6B, HIST1H1D, STK38, H2AFV, PACSIN2, U2AF1, RSL24D1, XRCC5, ESYT3, RPL29, SDF2L1, LRP1B, MSN, SEC23A, RPL7A, SNX18, PPIL1, RPS27A, IGHM, SUMO3, GTF2I, RUVBL1, KRT16, RBM8A, RPL8, SRSF9, ZC3HAV1L, GAPDH, ETV3, IGF2R, COL5A2, HNRNPD, ANP32B, WAC, TFAP2A, TTN, CBR3, ARGLU1, HNRNPAB, SRRT, ATP1B3, COPS7B, PRR12, ATF3, NOMO3, NOMO1, NOMO2, EYA3, C1orf198, MAZ, U2AF2, SSB, TRA2B, C1orf52, HMGB1, HMGB1P10, RPRD1A, HNRNPH3, EIF5A2, C1orf131, SEC13, MAPRE1, CSTF2T, SRSF3, LENG1, UPF1, HDGFRP2, RPS10P7, RPS10P11, RPS10, RPS10P13, RPS10P4, RPS10P22, DACH1, ANO1, NCOR1, MLX, SUMO1P3, SUMO1, WIZ, PFDN6, ARFIP2, ZHX3, EEF1B2, MBIP, BAG6, DENND2A, PRCC, SRSF1, EIF4ENIF1, SPTAN1, CDCA8, PLS3, API5P1, API5, PSMA4, DNTTIP1, AKAP8, NCOA3, SMTN, FBRS, SMARCE1, ERC1, WBP11, SPTBN1, NFRKB, OLA1, ZNF207, R3HDM1, TRIM33, SAFB, UBFD1, SRSF7, SRSF2, GATA6, VDAC1P1, VDAC1, IL16, GMNN, ILF2, MED4, QKI, VCL, MFAP1, SNAP29, PADI1, BCL9, BCL9L, PKM, GPATCH11, CASC3, PSMC6, CACYBP, RPL12P6, RPL12P32, RPL12P14, RPL12, RPL12P2, RPL12P35, RPL12P19, TPI1, TPI1P1, CHAF1A, MIA3, CIC, SDCBP, CA2, FKBP3, ACE, NKX2-5, CSTF2, PFDN2, UBTF, FAM207A, LOC729774, BRD8, C12orf45, C1orf35, TCF20, SOD1, SPAG7, MED8, ETS2, ALDOC, FKBP4, INCENP, CEP85, CECR2, TFE3, SUPT16HP1, SUPT16H, MAPT, HTATSF1, RPS18P12, RPS18P5, KPNA2, TMX1, CKAP4, HSPE1, COPRS, PTGES3, LAMP2, ERLIN2, CTNNBL1, TOMM22, NRBF2, C9orf78, NCOA6, MED26, RANBP1, LOC389842, LOC727803, HMGB3, CANX, PUS7, RPSAP19, RPSA, RPSAP18, RPSAP58, RPSAP15, RPSAP8, RPSAP9, RPSAP12, RPSAP29, RPSAP61, ARHGAP17, USF1, PSIP1, SNRPEP2, SNRPE, NUDT5, PPM1G, OTUB1, AHCY, COPS3, NSMCE2, SAE1, PROSER1, GRWD1, CREB5, TAF9B, RBM33, EDF1, PGK1, FAM114A2, SRRM1, RAD23B, CIAPIN1, CIAPIN1P, LRRC59, PABPN1, KMT2A, RPRD1B, GPATCH8, CCDC43, DGCR14, PPP1R2, ERICH1, EIF5A, EIF5AL1, BAG3, PCNA, SOX7, PNISR, FAM168A, MED15, SRSF11, SIRT1, RSF1, MAML1, HPRT1, SPDL1, CRTC3, CEP55, CDV3, ALYREF, RNF40, STOML2, DGCR8, NUCKS1, UBN2, PSMD7, WNT10A, HMBS, KHDRBS1, VBP1, NCSTN, CDCA2, SFSWAP, ZRANB2, DDB1, RBBP6, ZEB1, SRSF6, LOC644422, EIF2S1, RFX5, RPS19, RPS19P3, TALDO1, CWC15, CDCA5, LOC645086, C11orf58, TXN, STX12, PHRF1, BSG, TAF4, SH3GL1, LIN37, HRNR, FAM192A, RRBP1, KIAA0907, GOLGB1, PAX9, P4HB, CHMP5, LDHB, CALR, SUMO2P1, SUMO2, PDIA6, AHSA1, EN2, CCDC124, RPLP0P6, RPLP0P2, RPLP0P3, RPLP0, NIPBL, PDLIM4, PRKCSH, C15orf39, HNRNPDL, PDIA4, NUP210, RPLP2P3, RPLP2, PRDX4, DAZAP1, UBE2T, PHAX, AMOT, MARCKS, LOC284685, SMARCC1, BCORL1, RFC4, GLRX3, ANP32E, HYOU1, NPM3, ATF7IP, SARNP, TRA2A, HDGF, STIP1, PELP1, KCTD12, GLO1, PCF11, CLIC1, DNAJC8, RNF114, SLC4A1AP, FAM50A, GTF2A1, PRPF40A, CDC37, PPIAP22, PPIA, SMARCC2, MEGF11, KIAA1143, DENR, LAMP1, MYBL2, PITX1, UBE2MP1, UBE2M, CHTF8, OTX1, NACA, FNBP4, GTF2F2, GLTSCR1, GTF2E1, PQBP1, EMD, RNF113A, GPALPP1, SNRPA, RRP15, RPS25, RPS25P8, GMEB2, LNPEP, DNAJB1, IGBP1P1, IGBP1, HINT1, ARID1A, PPIB, ANXA11, MATR3, PPARGC1A, MCM2, UBASH3B, SFPQ, CAPN13, HEY1, BRCA1ETV4HOXD4, RFWD2, SAE1, UBA2, SMAD2, APP, HTT, ATXN1, STK11, TP63, JUN, CARM1, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for EWSR1_ETV4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for EWSR1_ETV4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneEWSR1C0553580Ewings sarcoma3CTD_human;HPO;ORPHANET
HgeneEWSR1C0206663Neuroectodermal Tumor, Primitive1CTD_human
TgeneETV4C0027627Neoplasm Metastasis1CTD_human
TgeneETV4C0033578Prostatic Neoplasms1CTD_human
TgeneETV4C1458155Mammary Neoplasms1CTD_human