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Fusion gene ID: 12046 |
FusionGeneSummary for ERN1_EIF3C |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ERN1_EIF3C | Fusion gene ID: 12046 | Hgene | Tgene | Gene symbol | ERN1 | EIF3C | Gene ID | 2081 | 8663 |
| Gene name | endoplasmic reticulum to nucleus signaling 1 | eukaryotic translation initiation factor 3 subunit C | |
| Synonyms | IRE1|IRE1P|IRE1a|hIRE1p | EIF3CL|EIF3S8|eIF3-p110 | |
| Cytomap | 17q23.3 | 16p11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | serine/threonine-protein kinase/endoribonuclease IRE1ER to nucleus signalling 1inositol-requiring 1inositol-requiring enzyme 1inositol-requiring protein 1ire1-alphaprotein kinase/endoribonuclease | eukaryotic translation initiation factor 3 subunit Ccell migration-inducing protein 17eIF3 p110eukaryotic translation initiation factor 3 subunit 8eukaryotic translation initiation factor 3, subunit 8 (110kD)eukaryotic translation initiation factor 3 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | O75460 | Q99613 | |
| Ensembl transtripts involved in fusion gene | ENST00000433197, ENST00000577567, ENST00000606895, | ENST00000566501, ENST00000331666, ENST00000395587, ENST00000564243, ENST00000566866, ENST00000565099, | |
| Fusion gene scores | * DoF score | 5 X 6 X 5=150 | 1 X 1 X 1=1 |
| # samples | 7 | 1 | |
| ** MAII score | log2(7/150*10)=-1.09953567355091 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ERN1 [Title/Abstract] AND EIF3C [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ERN1 | GO:0001935 | endothelial cell proliferation | 23529610 |
| Hgene | ERN1 | GO:0006468 | protein phosphorylation | 9637683 |
| Hgene | ERN1 | GO:0007257 | activation of JUN kinase activity | 10650002 |
| Hgene | ERN1 | GO:0033120 | positive regulation of RNA splicing | 11779464|19622636 |
| Hgene | ERN1 | GO:0034976 | response to endoplasmic reticulum stress | 10650002 |
| Hgene | ERN1 | GO:0035924 | cellular response to vascular endothelial growth factor stimulus | 23529610 |
| Hgene | ERN1 | GO:0036289 | peptidyl-serine autophosphorylation | 20103773 |
| Hgene | ERN1 | GO:0036498 | IRE1-mediated unfolded protein response | 19328063|29198525 |
| Hgene | ERN1 | GO:0046777 | protein autophosphorylation | 9637683|19328063 |
| Hgene | ERN1 | GO:0070054 | mRNA splicing, via endonucleolytic cleavage and ligation | 11779464|19622636|21317875 |
| Hgene | ERN1 | GO:0071333 | cellular response to glucose stimulus | 20103773 |
| Hgene | ERN1 | GO:0098787 | mRNA cleavage involved in mRNA processing | 21317875 |
| Hgene | ERN1 | GO:1901142 | insulin metabolic process | 20103773 |
| Tgene | EIF3C | GO:0006413 | translational initiation | 17581632 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-AO-A0J7-01A | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000433197 | ENST00000566501 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| In-frame | ENST00000433197 | ENST00000331666 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| In-frame | ENST00000433197 | ENST00000395587 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| In-frame | ENST00000433197 | ENST00000564243 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| In-frame | ENST00000433197 | ENST00000566866 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| 5CDS-3UTR | ENST00000433197 | ENST00000565099 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3CDS | ENST00000577567 | ENST00000566501 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3CDS | ENST00000577567 | ENST00000331666 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3CDS | ENST00000577567 | ENST00000395587 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3CDS | ENST00000577567 | ENST00000564243 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3CDS | ENST00000577567 | ENST00000566866 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3UTR | ENST00000577567 | ENST00000565099 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3CDS | ENST00000606895 | ENST00000566501 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3CDS | ENST00000606895 | ENST00000331666 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3CDS | ENST00000606895 | ENST00000395587 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3CDS | ENST00000606895 | ENST00000564243 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3CDS | ENST00000606895 | ENST00000566866 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
| intron-3UTR | ENST00000606895 | ENST00000565099 | ERN1 | chr17 | 62144031 | - | EIF3C | chr16 | 28734485 | + |
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FusionProtFeatures for ERN1_EIF3C |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ERN1 | EIF3C |
| Serine/threonine-protein kinase and endoribonucleasethat acts as a key sensor for the endoplasmic reticulum unfoldedprotein response (UPR) (PubMed:11779464, PubMed:11175748,PubMed:12637535, PubMed:9637683, PubMed:21317875). In unstressedcells, the endoplasmic reticulum luminal domain is maintained inits inactive monomeric state by binding to the endoplasmicreticulum chaperone HSPA5/BiP (PubMed:21317875). Accumulation ofmisfolded protein in the endoplasmic reticulum causes release ofHSPA5/BiP, allowing the luminal domain to homodimerize, promotingautophosphorylation of the kinase domain and subsequent activationof the endoribonuclease activity (PubMed:21317875). Theendoribonuclease activity is specific for XBP1 mRNA and excises 26nucleotides from XBP1 mRNA (PubMed:11779464, PubMed:24508390,PubMed:21317875). The resulting spliced transcript of XBP1 encodesa transcriptional activator protein that up-regulates expressionof UPR target genes (PubMed:11779464, PubMed:24508390,PubMed:21317875). {ECO:0000269|PubMed:11175748,ECO:0000269|PubMed:11779464, ECO:0000269|PubMed:12637535,ECO:0000269|PubMed:21317875, ECO:0000269|PubMed:9637683,ECO:0000305|PubMed:24508390}. | Component of the eukaryotic translation initiationfactor 3 (eIF-3) complex, which is required for several steps inthe initiation of protein synthesis (PubMed:17581632,PubMed:25849773, PubMed:27462815). The eIF-3 complex associateswith the 40S ribosome and facilitates the recruitment of eIF-1,eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNArecruitment to the 43S PIC and scanning of the mRNA for AUGrecognition. The eIF-3 complex is also required for disassemblyand recycling of post-termination ribosomal complexes andsubsequently prevents premature joining of the 40S and 60Sribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of asubset of mRNAs involved in cell proliferation, including cellcycling, differentiation and apoptosis, and uses different modesof RNA stem-loop binding to exert either translational activationor repression (PubMed:25849773). {ECO:0000255|HAMAP-Rule:MF_03002,ECO:0000269|PubMed:17581632, ECO:0000269|PubMed:25849773,ECO:0000269|PubMed:27462815}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >EIF3C | chr17:62144031 | chr16:28734485 | ENST00000331666 | + | 7 | 21 | 291_294 | 258 | 914 | Compositional bias | Note=Poly-Glu |
| Tgene | >EIF3C | chr17:62144031 | chr16:28734485 | ENST00000395587 | + | 7 | 21 | 291_294 | 258 | 914 | Compositional bias | Note=Poly-Glu |
| Tgene | >EIF3C | chr17:62144031 | chr16:28734485 | ENST00000566501 | + | 7 | 21 | 291_294 | 258 | 914 | Compositional bias | Note=Poly-Glu |
| Tgene | >EIF3C | chr17:62144031 | chr16:28734485 | ENST00000566866 | + | 6 | 20 | 291_294 | 258 | 914 | Compositional bias | Note=Poly-Glu |
| Tgene | >EIF3C | chr17:62144031 | chr16:28734485 | ENST00000331666 | + | 7 | 21 | 673_849 | 258 | 914 | Domain | PCI |
| Tgene | >EIF3C | chr17:62144031 | chr16:28734485 | ENST00000395587 | + | 7 | 21 | 673_849 | 258 | 914 | Domain | PCI |
| Tgene | >EIF3C | chr17:62144031 | chr16:28734485 | ENST00000566501 | + | 7 | 21 | 673_849 | 258 | 914 | Domain | PCI |
| Tgene | >EIF3C | chr17:62144031 | chr16:28734485 | ENST00000566866 | + | 6 | 20 | 673_849 | 258 | 914 | Domain | PCI |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000433197 | - | 8 | 22 | 571_832 | 280 | 978 | Domain | Protein kinase |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000433197 | - | 8 | 22 | 835_963 | 280 | 978 | Domain | KEN |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000606895 | - | 1 | 1 | 571_832 | -264 | 71 | Domain | Protein kinase |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000606895 | - | 1 | 1 | 835_963 | -264 | 71 | Domain | KEN |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000433197 | - | 8 | 22 | 577_585 | 280 | 978 | Nucleotide binding | ATP |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000433197 | - | 8 | 22 | 643_645 | 280 | 978 | Nucleotide binding | ATP |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000433197 | - | 8 | 22 | 690_693 | 280 | 978 | Nucleotide binding | ATP |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000606895 | - | 1 | 1 | 577_585 | -264 | 71 | Nucleotide binding | ATP |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000606895 | - | 1 | 1 | 643_645 | -264 | 71 | Nucleotide binding | ATP |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000606895 | - | 1 | 1 | 690_693 | -264 | 71 | Nucleotide binding | ATP |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000433197 | - | 8 | 22 | 906_907 | 280 | 978 | Region | Hydroxy-aryl-aldehyde inhibitor binding |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000606895 | - | 1 | 1 | 906_907 | -264 | 71 | Region | Hydroxy-aryl-aldehyde inhibitor binding |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000433197 | - | 8 | 22 | 19_443 | 280 | 978 | Topological domain | Lumenal |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000433197 | - | 8 | 22 | 465_977 | 280 | 978 | Topological domain | Cytoplasmic |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000606895 | - | 1 | 1 | 19_443 | -264 | 71 | Topological domain | Lumenal |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000606895 | - | 1 | 1 | 465_977 | -264 | 71 | Topological domain | Cytoplasmic |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000433197 | - | 8 | 22 | 444_464 | 280 | 978 | Transmembrane | Helical |
| Hgene | >ERN1 | chr17:62144031 | chr16:28734485 | ENST00000606895 | - | 1 | 1 | 444_464 | -264 | 71 | Transmembrane | Helical |
| Tgene | EIF3C | chr17:62144031 | chr16:28734485 | ENST00000331666 | + | 7 | 21 | 164_189 | 258 | 914 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Tgene | EIF3C | chr17:62144031 | chr16:28734485 | ENST00000331666 | + | 7 | 21 | 243_246 | 258 | 914 | Compositional bias | Note=Poly-Glu |
| Tgene | EIF3C | chr17:62144031 | chr16:28734485 | ENST00000395587 | + | 7 | 21 | 164_189 | 258 | 914 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Tgene | EIF3C | chr17:62144031 | chr16:28734485 | ENST00000395587 | + | 7 | 21 | 243_246 | 258 | 914 | Compositional bias | Note=Poly-Glu |
| Tgene | EIF3C | chr17:62144031 | chr16:28734485 | ENST00000566501 | + | 7 | 21 | 164_189 | 258 | 914 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Tgene | EIF3C | chr17:62144031 | chr16:28734485 | ENST00000566501 | + | 7 | 21 | 243_246 | 258 | 914 | Compositional bias | Note=Poly-Glu |
| Tgene | EIF3C | chr17:62144031 | chr16:28734485 | ENST00000566866 | + | 6 | 20 | 164_189 | 258 | 914 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Tgene | EIF3C | chr17:62144031 | chr16:28734485 | ENST00000566866 | + | 6 | 20 | 243_246 | 258 | 914 | Compositional bias | Note=Poly-Glu |
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FusionGeneSequence for ERN1_EIF3C |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000566501_chr16_28734485_+_936aa MPARRLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGSKNN EGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF DYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPF PKETEAKSKLTAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQ ARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEES ENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKA HQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQIL YNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYM AAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESL RTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQ >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000331666_chr16_28734485_+_936aa MPARRLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGSKNN EGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF DYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPF PKETEAKSKLTAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQ ARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEES ENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKA HQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQIL YNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYM AAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESL RTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQ >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000395587_chr16_28734485_+_936aa MPARRLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGSKNN EGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF DYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPF PKETEAKSKLTAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQ ARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEES ENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKA HQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQIL YNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYM AAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESL RTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQ >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000564243_chr16_28734485_+_936aa MPARRLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGSKNN EGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF DYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPF PKETEAKSKLTAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQ ARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEES ENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKA HQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQIL YNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYM AAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESL RTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQ >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000566866_chr16_28734485_+_936aa MPARRLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGSKNN EGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYF DYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPF PKETEAKSKLTAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPKMFAKGTEITHAVVIKKLNEILQ ARGKKGTDRAAQIELLQLLVQIAAENNLGEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANPNIFVGENILEES ENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHSQEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDYKA HQRQLTPPEGSSKSEQDQAENEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRWYQARDLMLMSHLQDNIQHADPPVQIL YNRTMVQLGICAFRQGLTKDAHNALLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELLECVYLVSAMLLEIPYM AAHESDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRKIQEESL RTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELMASLDQPTQTVVMHRTEPTAQQNLALQLAEKLGSLVENNERVFDHKQ |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000566501_chr16_28734485_+_2808nt ATGCCGGCCCGGCGGCTGCTGCTGCTGCTGACGCTGCTGCTGCCCGGCCTCGGGATTTTTGGAAGTACCAGCACAGTGACGCTTCCTGAA ACCTTGTTGTTTGTGTCAACGCTGGATGGAAGTTTGCATGCTGTCAGCAAGAGGACAGGCTCAATCAAATGGACTTTAAAAGAAGATCCA GTCCTGCAGGTCCCAACACATGTGGAAGAGCCTGCCTTTCTCCCAGATCCTAATGATGGCAGCCTGTATACGCTTGGAAGCAAGAATAAT GAAGGCCTGACGAAACTTCCTTTTACCATCCCAGAATTGGTGCAGGCATCCCCATGCCGAAGTTCAGATGGAATCCTCTACATGGGTAAA AAGCAGGACATCTGGTATGTTATTGACCTCCTGACCGGAGAGAAGCAGCAGACTTTGTCATCGGCCTTTGCAGATAGTCTCTGCCCATCA ACCTCTCTTCTGTATCTTGGGCGAACAGAATACACCATCACCATGTACGACACCAAAACCCGAGAGCTCCGGTGGAATGCCACCTACTTT GACTATGCGGCCTCACTGCCTGAGGACGACGTGGACTACAAGATGTCCCACTTTGTGTCCAATGGTGATGGGCTGGTGGTGACTGTGGAC AGTGAATCTGGGGACGTCCTGTGGATCCAAAACTACGCCTCCCCTGTGGTGGCCTTTTATGTCTGGCAGCGGGAGGGTCTGAGGAAGGTG ATGCACATCAATGTCGCTGTGGAGACCCTGCGCTATCTGACCTTCATGTCTGGGGAGGTGGGGCGCATCACAAAGTGGAAGTACCCGTTC CCCAAGGAGACAGAGGCCAAGAGCAAGCTGACGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGACAAAGCT AAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGCGGAGTG CCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATCCTACAG GCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTGGGAGAG GGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAGATGTGG GGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAAGAGAGT GAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACCAAAATA ATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTGCAGCGC TACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTACAAGGCC CATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTGTTGATG GAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCATGCTCTG CACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAGATCCTT TACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATCCAGTCG AGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAGCGGCGC CGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCCTACATG GCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTGCTGGGT CCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATCATCAAT GAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAGTCACTG AGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCCACTGTG CACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGCACTGAG CCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCACAAGCAG GGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAGCAGCAG >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000331666_chr16_28734485_+_2808nt ATGCCGGCCCGGCGGCTGCTGCTGCTGCTGACGCTGCTGCTGCCCGGCCTCGGGATTTTTGGAAGTACCAGCACAGTGACGCTTCCTGAA ACCTTGTTGTTTGTGTCAACGCTGGATGGAAGTTTGCATGCTGTCAGCAAGAGGACAGGCTCAATCAAATGGACTTTAAAAGAAGATCCA GTCCTGCAGGTCCCAACACATGTGGAAGAGCCTGCCTTTCTCCCAGATCCTAATGATGGCAGCCTGTATACGCTTGGAAGCAAGAATAAT GAAGGCCTGACGAAACTTCCTTTTACCATCCCAGAATTGGTGCAGGCATCCCCATGCCGAAGTTCAGATGGAATCCTCTACATGGGTAAA AAGCAGGACATCTGGTATGTTATTGACCTCCTGACCGGAGAGAAGCAGCAGACTTTGTCATCGGCCTTTGCAGATAGTCTCTGCCCATCA ACCTCTCTTCTGTATCTTGGGCGAACAGAATACACCATCACCATGTACGACACCAAAACCCGAGAGCTCCGGTGGAATGCCACCTACTTT GACTATGCGGCCTCACTGCCTGAGGACGACGTGGACTACAAGATGTCCCACTTTGTGTCCAATGGTGATGGGCTGGTGGTGACTGTGGAC AGTGAATCTGGGGACGTCCTGTGGATCCAAAACTACGCCTCCCCTGTGGTGGCCTTTTATGTCTGGCAGCGGGAGGGTCTGAGGAAGGTG ATGCACATCAATGTCGCTGTGGAGACCCTGCGCTATCTGACCTTCATGTCTGGGGAGGTGGGGCGCATCACAAAGTGGAAGTACCCGTTC CCCAAGGAGACAGAGGCCAAGAGCAAGCTGACGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGACAAAGCT AAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGCGGAGTG CCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATCCTACAG GCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTGGGAGAG GGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAGATGTGG GGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAAGAGAGT GAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACCAAAATA ATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTGCAGCGC TACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTACAAGGCC CATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTGTTGATG GAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCATGCTCTG CACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAGATCCTT TACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATCCAGTCG AGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAGCGGCGC CGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCCTACATG GCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTGCTGGGT CCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATCATCAAT GAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAGTCACTG AGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCCACTGTG CACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGCACTGAG CCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCACAAGCAG GGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAGCAGCAG >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000395587_chr16_28734485_+_2808nt ATGCCGGCCCGGCGGCTGCTGCTGCTGCTGACGCTGCTGCTGCCCGGCCTCGGGATTTTTGGAAGTACCAGCACAGTGACGCTTCCTGAA ACCTTGTTGTTTGTGTCAACGCTGGATGGAAGTTTGCATGCTGTCAGCAAGAGGACAGGCTCAATCAAATGGACTTTAAAAGAAGATCCA GTCCTGCAGGTCCCAACACATGTGGAAGAGCCTGCCTTTCTCCCAGATCCTAATGATGGCAGCCTGTATACGCTTGGAAGCAAGAATAAT GAAGGCCTGACGAAACTTCCTTTTACCATCCCAGAATTGGTGCAGGCATCCCCATGCCGAAGTTCAGATGGAATCCTCTACATGGGTAAA AAGCAGGACATCTGGTATGTTATTGACCTCCTGACCGGAGAGAAGCAGCAGACTTTGTCATCGGCCTTTGCAGATAGTCTCTGCCCATCA ACCTCTCTTCTGTATCTTGGGCGAACAGAATACACCATCACCATGTACGACACCAAAACCCGAGAGCTCCGGTGGAATGCCACCTACTTT GACTATGCGGCCTCACTGCCTGAGGACGACGTGGACTACAAGATGTCCCACTTTGTGTCCAATGGTGATGGGCTGGTGGTGACTGTGGAC AGTGAATCTGGGGACGTCCTGTGGATCCAAAACTACGCCTCCCCTGTGGTGGCCTTTTATGTCTGGCAGCGGGAGGGTCTGAGGAAGGTG ATGCACATCAATGTCGCTGTGGAGACCCTGCGCTATCTGACCTTCATGTCTGGGGAGGTGGGGCGCATCACAAAGTGGAAGTACCCGTTC CCCAAGGAGACAGAGGCCAAGAGCAAGCTGACGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGACAAAGCT AAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGCGGAGTG CCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATCCTACAG GCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTGGGAGAG GGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAGATGTGG GGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAAGAGAGT GAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACCAAAATA ATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTGCAGCGC TACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTACAAGGCC CATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTGTTGATG GAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCATGCTCTG CACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAGATCCTT TACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATCCAGTCG AGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAGCGGCGC CGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCCTACATG GCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTGCTGGGT CCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATCATCAAT GAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAGTCACTG AGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCCACTGTG CACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGCACTGAG CCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCACAAGCAG GGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAGCAGCAG >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000564243_chr16_28734485_+_2808nt ATGCCGGCCCGGCGGCTGCTGCTGCTGCTGACGCTGCTGCTGCCCGGCCTCGGGATTTTTGGAAGTACCAGCACAGTGACGCTTCCTGAA ACCTTGTTGTTTGTGTCAACGCTGGATGGAAGTTTGCATGCTGTCAGCAAGAGGACAGGCTCAATCAAATGGACTTTAAAAGAAGATCCA GTCCTGCAGGTCCCAACACATGTGGAAGAGCCTGCCTTTCTCCCAGATCCTAATGATGGCAGCCTGTATACGCTTGGAAGCAAGAATAAT GAAGGCCTGACGAAACTTCCTTTTACCATCCCAGAATTGGTGCAGGCATCCCCATGCCGAAGTTCAGATGGAATCCTCTACATGGGTAAA AAGCAGGACATCTGGTATGTTATTGACCTCCTGACCGGAGAGAAGCAGCAGACTTTGTCATCGGCCTTTGCAGATAGTCTCTGCCCATCA ACCTCTCTTCTGTATCTTGGGCGAACAGAATACACCATCACCATGTACGACACCAAAACCCGAGAGCTCCGGTGGAATGCCACCTACTTT GACTATGCGGCCTCACTGCCTGAGGACGACGTGGACTACAAGATGTCCCACTTTGTGTCCAATGGTGATGGGCTGGTGGTGACTGTGGAC AGTGAATCTGGGGACGTCCTGTGGATCCAAAACTACGCCTCCCCTGTGGTGGCCTTTTATGTCTGGCAGCGGGAGGGTCTGAGGAAGGTG ATGCACATCAATGTCGCTGTGGAGACCCTGCGCTATCTGACCTTCATGTCTGGGGAGGTGGGGCGCATCACAAAGTGGAAGTACCCGTTC CCCAAGGAGACAGAGGCCAAGAGCAAGCTGACGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGACAAAGCT AAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGCGGAGTG CCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATCCTACAG GCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTGGGAGAG GGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAGATGTGG GGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAAGAGAGT GAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACCAAAATA ATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTGCAGCGC TACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTACAAGGCC CATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTGTTGATG GAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCATGCTCTG CACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAGATCCTT TACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATCCAGTCG AGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAGCGGCGC CGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCCTACATG GCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTGCTGGGT CCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATCATCAAT GAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAGTCACTG AGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCCACTGTG CACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGCACTGAG CCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCACAAGCAG GGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAGCAGCAG >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000566866_chr16_28734485_+_2808nt ATGCCGGCCCGGCGGCTGCTGCTGCTGCTGACGCTGCTGCTGCCCGGCCTCGGGATTTTTGGAAGTACCAGCACAGTGACGCTTCCTGAA ACCTTGTTGTTTGTGTCAACGCTGGATGGAAGTTTGCATGCTGTCAGCAAGAGGACAGGCTCAATCAAATGGACTTTAAAAGAAGATCCA GTCCTGCAGGTCCCAACACATGTGGAAGAGCCTGCCTTTCTCCCAGATCCTAATGATGGCAGCCTGTATACGCTTGGAAGCAAGAATAAT GAAGGCCTGACGAAACTTCCTTTTACCATCCCAGAATTGGTGCAGGCATCCCCATGCCGAAGTTCAGATGGAATCCTCTACATGGGTAAA AAGCAGGACATCTGGTATGTTATTGACCTCCTGACCGGAGAGAAGCAGCAGACTTTGTCATCGGCCTTTGCAGATAGTCTCTGCCCATCA ACCTCTCTTCTGTATCTTGGGCGAACAGAATACACCATCACCATGTACGACACCAAAACCCGAGAGCTCCGGTGGAATGCCACCTACTTT GACTATGCGGCCTCACTGCCTGAGGACGACGTGGACTACAAGATGTCCCACTTTGTGTCCAATGGTGATGGGCTGGTGGTGACTGTGGAC AGTGAATCTGGGGACGTCCTGTGGATCCAAAACTACGCCTCCCCTGTGGTGGCCTTTTATGTCTGGCAGCGGGAGGGTCTGAGGAAGGTG ATGCACATCAATGTCGCTGTGGAGACCCTGCGCTATCTGACCTTCATGTCTGGGGAGGTGGGGCGCATCACAAAGTGGAAGTACCCGTTC CCCAAGGAGACAGAGGCCAAGAGCAAGCTGACGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGACAAAGCT AAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGCGGAGTG CCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATCCTACAG GCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTGGGAGAG GGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAGATGTGG GGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAAGAGAGT GAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACCAAAATA ATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTGCAGCGC TACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTACAAGGCC CATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTGTTGATG GAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCATGCTCTG CACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAGATCCTT TACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATCCAGTCG AGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAGCGGCGC CGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCCTACATG GCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTGCTGGGT CCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATCATCAAT GAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAGTCACTG AGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCCACTGTG CACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGCACTGAG CCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCACAAGCAG GGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAGCAGCAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000566501_chr16_28734485_+_2989nt GTCCGCTGAGGCTCGGTCACCGCCTCGCTGTCGTCGCGGCGCCCCCGCCCCGTCCTCTGTCCGTACCGCCCCCGGAGCCAGGGCCGAGTC CTCGCCATGCCGGCCCGGCGGCTGCTGCTGCTGCTGACGCTGCTGCTGCCCGGCCTCGGGATTTTTGGAAGTACCAGCACAGTGACGCTT CCTGAAACCTTGTTGTTTGTGTCAACGCTGGATGGAAGTTTGCATGCTGTCAGCAAGAGGACAGGCTCAATCAAATGGACTTTAAAAGAA GATCCAGTCCTGCAGGTCCCAACACATGTGGAAGAGCCTGCCTTTCTCCCAGATCCTAATGATGGCAGCCTGTATACGCTTGGAAGCAAG AATAATGAAGGCCTGACGAAACTTCCTTTTACCATCCCAGAATTGGTGCAGGCATCCCCATGCCGAAGTTCAGATGGAATCCTCTACATG GGTAAAAAGCAGGACATCTGGTATGTTATTGACCTCCTGACCGGAGAGAAGCAGCAGACTTTGTCATCGGCCTTTGCAGATAGTCTCTGC CCATCAACCTCTCTTCTGTATCTTGGGCGAACAGAATACACCATCACCATGTACGACACCAAAACCCGAGAGCTCCGGTGGAATGCCACC TACTTTGACTATGCGGCCTCACTGCCTGAGGACGACGTGGACTACAAGATGTCCCACTTTGTGTCCAATGGTGATGGGCTGGTGGTGACT GTGGACAGTGAATCTGGGGACGTCCTGTGGATCCAAAACTACGCCTCCCCTGTGGTGGCCTTTTATGTCTGGCAGCGGGAGGGTCTGAGG AAGGTGATGCACATCAATGTCGCTGTGGAGACCCTGCGCTATCTGACCTTCATGTCTGGGGAGGTGGGGCGCATCACAAAGTGGAAGTAC CCGTTCCCCAAGGAGACAGAGGCCAAGAGCAAGCTGACGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGAC AAAGCTAAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGC GGAGTGCCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATC CTACAGGCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTG GGAGAGGGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAG ATGTGGGGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAA GAGAGTGAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACC AAAATAATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTG CAGCGCTACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTAC AAGGCCCATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTG TTGATGGAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCAT GCTCTGCACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAG ATCCTTTACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATC CAGTCGAGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAG CGGCGCCGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCC TACATGGCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTG CTGGGTCCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATC ATCAATGAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAG TCACTGAGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCC ACTGTGCACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGC ACTGAGCCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCAC AAGCAGGGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAG CAGCAGTCTCAGACGGCCTACTGAGCTCTCCACTCTGTTTCCCGCCTGGGCCATCCAACCTTGAAGTCCTAAACCACACCTCAGTCACTA >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000331666_chr16_28734485_+_3121nt GTCCGCTGAGGCTCGGTCACCGCCTCGCTGTCGTCGCGGCGCCCCCGCCCCGTCCTCTGTCCGTACCGCCCCCGGAGCCAGGGCCGAGTC CTCGCCATGCCGGCCCGGCGGCTGCTGCTGCTGCTGACGCTGCTGCTGCCCGGCCTCGGGATTTTTGGAAGTACCAGCACAGTGACGCTT CCTGAAACCTTGTTGTTTGTGTCAACGCTGGATGGAAGTTTGCATGCTGTCAGCAAGAGGACAGGCTCAATCAAATGGACTTTAAAAGAA GATCCAGTCCTGCAGGTCCCAACACATGTGGAAGAGCCTGCCTTTCTCCCAGATCCTAATGATGGCAGCCTGTATACGCTTGGAAGCAAG AATAATGAAGGCCTGACGAAACTTCCTTTTACCATCCCAGAATTGGTGCAGGCATCCCCATGCCGAAGTTCAGATGGAATCCTCTACATG GGTAAAAAGCAGGACATCTGGTATGTTATTGACCTCCTGACCGGAGAGAAGCAGCAGACTTTGTCATCGGCCTTTGCAGATAGTCTCTGC CCATCAACCTCTCTTCTGTATCTTGGGCGAACAGAATACACCATCACCATGTACGACACCAAAACCCGAGAGCTCCGGTGGAATGCCACC TACTTTGACTATGCGGCCTCACTGCCTGAGGACGACGTGGACTACAAGATGTCCCACTTTGTGTCCAATGGTGATGGGCTGGTGGTGACT GTGGACAGTGAATCTGGGGACGTCCTGTGGATCCAAAACTACGCCTCCCCTGTGGTGGCCTTTTATGTCTGGCAGCGGGAGGGTCTGAGG AAGGTGATGCACATCAATGTCGCTGTGGAGACCCTGCGCTATCTGACCTTCATGTCTGGGGAGGTGGGGCGCATCACAAAGTGGAAGTAC CCGTTCCCCAAGGAGACAGAGGCCAAGAGCAAGCTGACGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGAC AAAGCTAAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGC GGAGTGCCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATC CTACAGGCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTG GGAGAGGGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAG ATGTGGGGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAA GAGAGTGAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACC AAAATAATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTG CAGCGCTACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTAC AAGGCCCATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTG TTGATGGAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCAT GCTCTGCACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAG ATCCTTTACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATC CAGTCGAGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAG CGGCGCCGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCC TACATGGCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTG CTGGGTCCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATC ATCAATGAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAG TCACTGAGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCC ACTGTGCACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGC ACTGAGCCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCAC AAGCAGGGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAG CAGCAGTCTCAGACGGCCTACTGAGCTCTCCACTCTGTTTCCCGCCTGGGCCATCCAACCTTGAAGTCCTAAACCACACCTCAGTCACTA AAGGTCTGTTTAAAGTTGTTCTGGTTGATTGCTTGTTGCCACAAAGGTGTGTTGAGCCCATTCATTTGCTGATTATATTTCTGAGCTGCT >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000395587_chr16_28734485_+_3118nt GTCCGCTGAGGCTCGGTCACCGCCTCGCTGTCGTCGCGGCGCCCCCGCCCCGTCCTCTGTCCGTACCGCCCCCGGAGCCAGGGCCGAGTC CTCGCCATGCCGGCCCGGCGGCTGCTGCTGCTGCTGACGCTGCTGCTGCCCGGCCTCGGGATTTTTGGAAGTACCAGCACAGTGACGCTT CCTGAAACCTTGTTGTTTGTGTCAACGCTGGATGGAAGTTTGCATGCTGTCAGCAAGAGGACAGGCTCAATCAAATGGACTTTAAAAGAA GATCCAGTCCTGCAGGTCCCAACACATGTGGAAGAGCCTGCCTTTCTCCCAGATCCTAATGATGGCAGCCTGTATACGCTTGGAAGCAAG AATAATGAAGGCCTGACGAAACTTCCTTTTACCATCCCAGAATTGGTGCAGGCATCCCCATGCCGAAGTTCAGATGGAATCCTCTACATG GGTAAAAAGCAGGACATCTGGTATGTTATTGACCTCCTGACCGGAGAGAAGCAGCAGACTTTGTCATCGGCCTTTGCAGATAGTCTCTGC CCATCAACCTCTCTTCTGTATCTTGGGCGAACAGAATACACCATCACCATGTACGACACCAAAACCCGAGAGCTCCGGTGGAATGCCACC TACTTTGACTATGCGGCCTCACTGCCTGAGGACGACGTGGACTACAAGATGTCCCACTTTGTGTCCAATGGTGATGGGCTGGTGGTGACT GTGGACAGTGAATCTGGGGACGTCCTGTGGATCCAAAACTACGCCTCCCCTGTGGTGGCCTTTTATGTCTGGCAGCGGGAGGGTCTGAGG AAGGTGATGCACATCAATGTCGCTGTGGAGACCCTGCGCTATCTGACCTTCATGTCTGGGGAGGTGGGGCGCATCACAAAGTGGAAGTAC CCGTTCCCCAAGGAGACAGAGGCCAAGAGCAAGCTGACGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGAC AAAGCTAAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGC GGAGTGCCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATC CTACAGGCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTG GGAGAGGGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAG ATGTGGGGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAA GAGAGTGAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACC AAAATAATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTG CAGCGCTACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTAC AAGGCCCATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTG TTGATGGAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCAT GCTCTGCACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAG ATCCTTTACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATC CAGTCGAGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAG CGGCGCCGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCC TACATGGCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTG CTGGGTCCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATC ATCAATGAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAG TCACTGAGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCC ACTGTGCACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGC ACTGAGCCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCAC AAGCAGGGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAG CAGCAGTCTCAGACGGCCTACTGAGCTCTCCACTCTGTTTCCCGCCTGGGCCATCCAACCTTGAAGTCCTAAACCACACCTCAGTCACTA AAGGTCTGTTTAAAGTTGTTCTGGTTGATTGCTTGTTGCCACAAAGGTGTGTTGAGCCCATTCATTTGCTGATTATATTTCTGAGCTGCT >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000564243_chr16_28734485_+_2987nt GTCCGCTGAGGCTCGGTCACCGCCTCGCTGTCGTCGCGGCGCCCCCGCCCCGTCCTCTGTCCGTACCGCCCCCGGAGCCAGGGCCGAGTC CTCGCCATGCCGGCCCGGCGGCTGCTGCTGCTGCTGACGCTGCTGCTGCCCGGCCTCGGGATTTTTGGAAGTACCAGCACAGTGACGCTT CCTGAAACCTTGTTGTTTGTGTCAACGCTGGATGGAAGTTTGCATGCTGTCAGCAAGAGGACAGGCTCAATCAAATGGACTTTAAAAGAA GATCCAGTCCTGCAGGTCCCAACACATGTGGAAGAGCCTGCCTTTCTCCCAGATCCTAATGATGGCAGCCTGTATACGCTTGGAAGCAAG AATAATGAAGGCCTGACGAAACTTCCTTTTACCATCCCAGAATTGGTGCAGGCATCCCCATGCCGAAGTTCAGATGGAATCCTCTACATG GGTAAAAAGCAGGACATCTGGTATGTTATTGACCTCCTGACCGGAGAGAAGCAGCAGACTTTGTCATCGGCCTTTGCAGATAGTCTCTGC CCATCAACCTCTCTTCTGTATCTTGGGCGAACAGAATACACCATCACCATGTACGACACCAAAACCCGAGAGCTCCGGTGGAATGCCACC TACTTTGACTATGCGGCCTCACTGCCTGAGGACGACGTGGACTACAAGATGTCCCACTTTGTGTCCAATGGTGATGGGCTGGTGGTGACT GTGGACAGTGAATCTGGGGACGTCCTGTGGATCCAAAACTACGCCTCCCCTGTGGTGGCCTTTTATGTCTGGCAGCGGGAGGGTCTGAGG AAGGTGATGCACATCAATGTCGCTGTGGAGACCCTGCGCTATCTGACCTTCATGTCTGGGGAGGTGGGGCGCATCACAAAGTGGAAGTAC CCGTTCCCCAAGGAGACAGAGGCCAAGAGCAAGCTGACGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGAC AAAGCTAAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGC GGAGTGCCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATC CTACAGGCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTG GGAGAGGGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAG ATGTGGGGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAA GAGAGTGAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACC AAAATAATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTG CAGCGCTACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTAC AAGGCCCATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTG TTGATGGAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCAT GCTCTGCACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAG ATCCTTTACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATC CAGTCGAGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAG CGGCGCCGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCC TACATGGCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTG CTGGGTCCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATC ATCAATGAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAG TCACTGAGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCC ACTGTGCACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGC ACTGAGCCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCAC AAGCAGGGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAG CAGCAGTCTCAGACGGCCTACTGAGCTCTCCACTCTGTTTCCCGCCTGGGCCATCCAACCTTGAAGTCCTAAACCACACCTCAGTCACTA >In-frame_ERN1_ENST00000433197_chr17_62144031_-_EIF3C_ENST00000566866_chr16_28734485_+_2988nt GTCCGCTGAGGCTCGGTCACCGCCTCGCTGTCGTCGCGGCGCCCCCGCCCCGTCCTCTGTCCGTACCGCCCCCGGAGCCAGGGCCGAGTC CTCGCCATGCCGGCCCGGCGGCTGCTGCTGCTGCTGACGCTGCTGCTGCCCGGCCTCGGGATTTTTGGAAGTACCAGCACAGTGACGCTT CCTGAAACCTTGTTGTTTGTGTCAACGCTGGATGGAAGTTTGCATGCTGTCAGCAAGAGGACAGGCTCAATCAAATGGACTTTAAAAGAA GATCCAGTCCTGCAGGTCCCAACACATGTGGAAGAGCCTGCCTTTCTCCCAGATCCTAATGATGGCAGCCTGTATACGCTTGGAAGCAAG AATAATGAAGGCCTGACGAAACTTCCTTTTACCATCCCAGAATTGGTGCAGGCATCCCCATGCCGAAGTTCAGATGGAATCCTCTACATG GGTAAAAAGCAGGACATCTGGTATGTTATTGACCTCCTGACCGGAGAGAAGCAGCAGACTTTGTCATCGGCCTTTGCAGATAGTCTCTGC CCATCAACCTCTCTTCTGTATCTTGGGCGAACAGAATACACCATCACCATGTACGACACCAAAACCCGAGAGCTCCGGTGGAATGCCACC TACTTTGACTATGCGGCCTCACTGCCTGAGGACGACGTGGACTACAAGATGTCCCACTTTGTGTCCAATGGTGATGGGCTGGTGGTGACT GTGGACAGTGAATCTGGGGACGTCCTGTGGATCCAAAACTACGCCTCCCCTGTGGTGGCCTTTTATGTCTGGCAGCGGGAGGGTCTGAGG AAGGTGATGCACATCAATGTCGCTGTGGAGACCCTGCGCTATCTGACCTTCATGTCTGGGGAGGTGGGGCGCATCACAAAGTGGAAGTAC CCGTTCCCCAAGGAGACAGAGGCCAAGAGCAAGCTGACGGCACCCACCACAGATGAGGACAAGAAGGCAGCCGAGAAGAAACGGGAGGAC AAAGCTAAGAAGAAGCACGACAGGAAATCCAAGCGCCTGGATGAGGAGGAGGAGGACAATGAAGGCGGGGAGTGGGAAAGGGTCCGGGGC GGAGTGCCGTTGGTTAAGGAGAAGCCAAAAATGTTTGCCAAGGGAACTGAGATCACCCATGCTGTTGTTATCAAGAAACTGAATGAGATC CTACAGGCACGAGGCAAGAAGGGAACTGATCGTGCTGCCCAGATTGAGCTGCTGCAACTGCTGGTTCAGATTGCAGCGGAAAACAACCTG GGAGAGGGCGTCATTGTCAAGATCAAGTTCAATATCATCGCCTCTCTCTATGACTACAACCCCAACCTGGCAACCTACATGAAGCCAGAG ATGTGGGGGAAGTGCCTGGACTGCATCAATGAGCTGATGGATATCCTGTTTGCAAATCCCAACATTTTTGTTGGAGAGAATATTCTGGAA GAGAGTGAGAACCTGCACAACGCTGACCAGCCACTGCGTGTCCGTGGCTGCATCCTAACTCTGGTGGAACGAATGGATGAAGAATTTACC AAAATAATGCAAAATACTGACCCTCACTCCCAAGAGTACGTGGAGCACTTGAAGGATGAGGCCCAGGTGTGTGCCATCATCGAGCGTGTG CAGCGCTACCTGGAGGAGAAGGGCACTACCGAGGAGGTCTGCCGCATCTACCTGCTGCGCATCCTGCACACCTACTACAAGTTTGATTAC AAGGCCCATCAGCGACAGCTGACCCCGCCTGAGGGCTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAATGAGGGCGAGGACTCGGCTGTG TTGATGGAGAGACTGTGCAAGTACATCTACGCCAAGGACCGCACAGACCGGATCCGCACATGTGCCATCCTCTGCCACATCTACCACCAT GCTCTGCACTCGCGCTGGTACCAGGCCCGCGACCTCATGCTCATGAGCCACTTGCAGGACAACATTCAGCATGCAGACCCGCCAGTGCAG ATCCTTTACAACCGCACCATGGTGCAGCTGGGCATCTGTGCCTTCCGCCAAGGCCTGACCAAGGACGCACACAACGCCCTGCTGGACATC CAGTCGAGTGGCCGAGCCAAGGAGCTTCTGGGCCAGGGCCTGCTGCTGCGCAGCCTGCAGGAGCGCAACCAGGAGCAGGAGAAGGTGGAG CGGCGCCGTCAGGTCCCCTTCCACCTGCACATCAACCTGGAGCTGCTGGAGTGTGTCTACCTGGTGTCTGCCATGCTCCTGGAGATCCCC TACATGGCCGCCCATGAGAGCGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCACCACCAGCTGCGCGTGGGCGAGCGACAGCCCCTG CTGGGTCCCCCTGAGTCCATGCGGGAACATGTGGTCGCTGCCTCCAAGGCCATGAAGATGGGTGACTGGAAGACCTGTCACAGTTTTATC ATCAATGAGAAGATGAATGGGAAAGTGTGGGACCTTTTCCCCGAGGCTGACAAAGTCCGCACCATGCTGGTTAGGAAGATCCAGGAAGAG TCACTGAGGACCTACCTCTTCACCTACAGCAGTGTCTATGACTCCATCAGCATGGAGACGCTGTCAGACATGTTTGAGCTGGATCTGCCC ACTGTGCACTCCATCATCAGCAAAATGATCATTAATGAGGAGCTGATGGCCTCCCTGGACCAGCCAACACAGACAGTGGTGATGCACCGC ACTGAGCCCACTGCCCAGCAGAACCTGGCTCTGCAGCTGGCCGAGAAGCTGGGCAGCCTGGTGGAGAACAACGAACGGGTGTTTGACCAC AAGCAGGGCACCTACGGGGGCTACTTCCGAGACCAGAAGGACGGCTACCGCAAAAACGAGGGCTACATGCGCCGCGGTGGCTACCGCCAG CAGCAGTCTCAGACGGCCTACTGAGCTCTCCACTCTGTTTCCCGCCTGGGCCATCCAACCTTGAAGTCCTAAACCACACCTCAGTCACTA |
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FusionGenePPI for ERN1_EIF3C |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ERN1 | TRAF2, ERN1, HSPA5, MAP3K5, HSP90AA1, TAOK3, PSEN1, SYVN1, COPS5, USP14, DERL1, DERL3, SEL1L, SRPK2, TRAF6, RNF13, STUB1, OTUB1, UCHL1, FBXL21, FBXO11, MYC, TP53, RIPK1, WDYHV1, SCGB2A2, LYPD4, ZNRF4 | EIF3C | EIF3G, EIF3A, EIF3K, AAGAB, MTOR, RPS6KB1, EIF6, EIF3B, EIF3J, RPTOR, EIF3H, EIF3F, USP20, USP3, CHAF1A, TADA2A, CD4, HDAC5, CALM1, HMOX2, RPS6KA3, MAPK6, PFDN1, RAD21, CUL3, CDK2, EIF3E, EIF3D, EIF3I, EIF3L, EIF3M, RPL8, RPS24, EIF5B, RPS4X, RPS3A, NCL, ABCC1, PDHX, PAM16, CPT1A, MRPS35, MRPL15, GADD45GIP1, MRPL2, TMED10, MYH9, NAP1L4, NAP1L1, DDX3X, SMAD9, CD81, IGSF8, ICAM1, TARDBP, NELFB, EIF2B3, G3BP1, HNRNPU, LARP1, MAP2, SHFM1, CCDC8, CSNK2A1, RSPH9, RPL7, SFN, NTRK1, KRAS, HERC2, XPO1, NPM1, RPL10, GAN, MCM2, DUSP4, EIF4A1, PSMD12, GPBP1L1, GPBP1, CYLD, DLD, UBE2A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ERN1_EIF3C |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ERN1_EIF3C |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ERN1 | C0014544 | Epilepsy | 1 | CTD_human |
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