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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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Fusion gene ID: 12020

FusionGeneSummary for ERG_ZNRF3

check button Fusion gene summary
Fusion gene informationFusion gene name: ERG_ZNRF3
Fusion gene ID: 12020
HgeneTgene
Gene symbol

ERG

ZNRF3

Gene ID

2078

84133

Gene nameERG, ETS transcription factorzinc and ring finger 3
Synonymserg-3|p55BK747E2.3|RNF203
Cytomap

21q22.2

22q12.1

Type of geneprotein-codingprotein-coding
Descriptiontranscriptional regulator ERGFUS/ERG fusion proteinTMPRSS2/ERG fusionerythroblast transformation-specific transcription factor ERG variant 10ets-relatedtranscriptional regulator ERG (transforming protein ERG)v-ets avian erythroblastosis virus E26 onE3 ubiquitin-protein ligase ZNRF3CTA-292E10.6RING finger protein 203RING-type E3 ubiquitin transferase ZNRF3novel C3HC4 type Zinc finger (ring finger)zinc/RING finger protein 3
Modification date2018052320180523
UniProtAcc

P11308

Q9ULT6

Ensembl transtripts involved in fusion geneENST00000398907, ENST00000398905, 
ENST00000288319, ENST00000398897, 
ENST00000398911, ENST00000398910, 
ENST00000417133, ENST00000442448, 
ENST00000453032, ENST00000398919, 
ENST00000429727, ENST00000485493, 
ENST00000544604, ENST00000332811, 
ENST00000402174, ENST00000406323, 
Fusion gene scores* DoF score15 X 4 X 3=1807 X 6 X 6=252
# samples 199
** MAII scorelog2(19/180*10)=0.0780025120012732
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(9/252*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ERG [Title/Abstract] AND ZNRF3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneERG

GO:0045944

positive regulation of transcription by RNA polymerase II

18195090|23913826

TgeneZNRF3

GO:0016567

protein ubiquitination

22575959


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVPRADTCGA-J4-A83I-01AERGchr21

39947586

-ZNRF3chr22

29383064

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000398907ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398907ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398907ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398907ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398905ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398905ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398905ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000398905ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000288319ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000288319ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000288319ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000288319ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000398897ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000398897ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000398897ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000398897ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398911ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398911ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398911ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398911ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000398910ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000398910ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000398910ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000398910ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000417133ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000417133ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000417133ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000417133ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000442448ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000442448ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000442448ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
Frame-shitENST00000442448ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000453032ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000453032ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000453032ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000453032ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398919ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398919ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398919ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
In-frameENST00000398919ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000429727ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000429727ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000429727ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
intron-3CDSENST00000429727ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000485493ENST00000544604ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000485493ENST00000332811ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000485493ENST00000402174ERGchr21

39947586

-ZNRF3chr22

29383064

+
5UTR-3CDSENST00000485493ENST00000406323ERGchr21

39947586

-ZNRF3chr22

29383064

+

Top

FusionProtFeatures for ERG_ZNRF3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ERG

P11308

ZNRF3

Q9ULT6

Transcriptional regulator. May participate intranscriptional regulation through the recruitment of SETDB1histone methyltransferase and subsequent modification of localchromatin structure. E3 ubiquitin-protein ligase that acts as a negativeregulator of the Wnt signaling pathway by mediating theubiquitination and subsequent degradation of Wnt receptor complexcomponents Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in theintestinal stem cell zone by inhibiting the Wnt signaling pathway,thereby resticting the size of the intestinal stem cell zone.{ECO:0000269|PubMed:22575959}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for ERG_ZNRF3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000544604_chr22_29383064_+_850aa
MIQTVPDPAAHIKMHPLGLCNNNDEEDLTETGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLK
RPVVTVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMETRKF
NSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNLSRG
RQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLTSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAHPFR
RPKLSGRSFSKAACFSQTETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCTHGHRS
VCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDTDPFIYRSRSPCRASEAGGSGSSGRGPALCFEGS
PPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCCEPQ
PSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFTEEKQVARGGGGGSGCYTEDYSVSVQ
YTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPPEEA

>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000332811_chr22_29383064_+_850aa
MIQTVPDPAAHIKMHPLGLCNNNDEEDLTETGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLK
RPVVTVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMETRKF
NSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNLSRG
RQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLTSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAHPFR
RPKLSGRSFSKAACFSQTETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCTHGHRS
VCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDTDPFIYRSRSPCRASEAGGSGSSGRGPALCFEGS
PPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCCEPQ
PSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFTEEKQVARGGGGGSGCYTEDYSVSVQ
YTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPPEEA

>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000402174_chr22_29383064_+_850aa
MIQTVPDPAAHIKMHPLGLCNNNDEEDLTETGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLK
RPVVTVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMETRKF
NSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNLSRG
RQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLTSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAHPFR
RPKLSGRSFSKAACFSQTETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCTHGHRS
VCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDTDPFIYRSRSPCRASEAGGSGSSGRGPALCFEGS
PPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCCEPQ
PSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFTEEKQVARGGGGGSGCYTEDYSVSVQ
YTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPPEEA

>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000406323_chr22_29383064_+_858aa
MIQTVPDPAAHIKFSFHFIS_MHPLGLCNNNDEEDLTETGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLN
QGSEDPLKRPVVTVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQAL
EKMETRKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCV
ETSNLSRGRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLTSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRA
YSPAHPFRRPKLSGRSFSKAACFSQTETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSF
SCTHGHRSVCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDTDPFIYRSRSPCRASEAGGSGSSGRG
PALCFEGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPS
CACCCEPQPSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFTEEKQVARGGGGGSGCYT
EDYSVSVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLR

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000544604_chr22_29383064_+_850aa
MIQTVPDPAAHIKMHPLGLCNNNDEEDLTETGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLK
RPVVTVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMETRKF
NSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNLSRG
RQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLTSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAHPFR
RPKLSGRSFSKAACFSQTETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCTHGHRS
VCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDTDPFIYRSRSPCRASEAGGSGSSGRGPALCFEGS
PPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCCEPQ
PSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFTEEKQVARGGGGGSGCYTEDYSVSVQ
YTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPPEEA

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000332811_chr22_29383064_+_850aa
MIQTVPDPAAHIKMHPLGLCNNNDEEDLTETGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLK
RPVVTVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMETRKF
NSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNLSRG
RQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLTSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAHPFR
RPKLSGRSFSKAACFSQTETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCTHGHRS
VCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDTDPFIYRSRSPCRASEAGGSGSSGRGPALCFEGS
PPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCCEPQ
PSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFTEEKQVARGGGGGSGCYTEDYSVSVQ
YTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPPEEA

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000402174_chr22_29383064_+_850aa
MIQTVPDPAAHIKMHPLGLCNNNDEEDLTETGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLK
RPVVTVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMETRKF
NSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNLSRG
RQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLTSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRAYSPAHPFR
RPKLSGRSFSKAACFSQTETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCTHGHRS
VCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDTDPFIYRSRSPCRASEAGGSGSSGRGPALCFEGS
PPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCCEPQ
PSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFTEEKQVARGGGGGSGCYTEDYSVSVQ
YTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPPEEA

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000406323_chr22_29383064_+_858aa
MIQTVPDPAAHIKFSFHFIS_MHPLGLCNNNDEEDLTETGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLN
QGSEDPLKRPVVTVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQAL
EKMETRKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCV
ETSNLSRGRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLTSPQTPAYIRSYPPLHLDHSLAAHRCGLEHRA
YSPAHPFRRPKLSGRSFSKAACFSQTETMYQHYYFQGLSYPEQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSF
SCTHGHRSVCSGYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDTDPFIYRSRSPCRASEAGGSGSSGRG
PALCFEGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVSTCSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPS
CACCCEPQPSPAGPSAGAAGSSTLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPCCFTEEKQVARGGGGGSGCYT
EDYSVSVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCDLGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLR


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000544604_chr22_29383064_+_2550nt
ATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAA
TATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTA
CAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAG
AGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCAC
CGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTT
GTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTC
AACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTG
GAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCAC
CACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGT
CGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATG
GACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGC
AGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGC
AGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTC
AGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTG
CTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCG
GTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCT
GTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTC
ATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCC
CCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAG
GTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTC
GAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAG
CCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGT
GGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTG
CCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAG
TACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGAC
TGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCAC
AGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCG
GGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCAC

>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000332811_chr22_29383064_+_2550nt
ATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAA
TATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTA
CAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAG
AGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCAC
CGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTT
GTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTC
AACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTG
GAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCAC
CACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGT
CGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATG
GACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGC
AGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGC
AGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTC
AGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTG
CTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCG
GTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCT
GTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTC
ATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCC
CCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAG
GTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTC
GAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAG
CCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGT
GGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTG
CCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAG
TACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGAC
TGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCAC
AGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCG
GGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCAC

>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000402174_chr22_29383064_+_2550nt
ATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAA
TATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTA
CAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAG
AGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCAC
CGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTT
GTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTC
AACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTG
GAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCAC
CACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGT
CGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATG
GACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGC
AGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGC
AGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTC
AGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTG
CTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCG
GTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCT
GTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTC
ATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCC
CCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAG
GTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTC
GAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAG
CCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGT
GGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTG
CCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAG
TACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGAC
TGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCAC
AGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCG
GGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCAC

>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000406323_chr22_29383064_+_2574nt
ATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGTTTTCTTTCCATTTTATTTCCTAGATGCACCCACTGGGCCTATGTAATAAC
AATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGTC
CTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAAC
CAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAAA
GTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTC
TCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTA
GAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCC
ACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTGC
GTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTG
GAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCCA
GCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTCC
CCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCC
TACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTAC
CAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTT
CCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTC
AGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAG
TGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCC
CTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGA
CCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGC
CCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAAT
AGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCG
TGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTC
TACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGACA
GATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACT
GAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATC
CCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGA
GGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGG
CCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCACT

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000544604_chr22_29383064_+_2550nt
ATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAA
TATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTA
CAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAG
AGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCAC
CGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTT
GTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTC
AACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTG
GAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCAC
CACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGT
CGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATG
GACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGC
AGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGC
AGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTC
AGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTG
CTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCG
GTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCT
GTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTC
ATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCC
CCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAG
GTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTC
GAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAG
CCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGT
GGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTG
CCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAG
TACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGAC
TGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCAC
AGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCG
GGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCAC

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000332811_chr22_29383064_+_2550nt
ATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAA
TATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTA
CAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAG
AGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCAC
CGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTT
GTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTC
AACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTG
GAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCAC
CACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGT
CGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATG
GACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGC
AGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGC
AGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTC
AGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTG
CTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCG
GTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCT
GTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTC
ATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCC
CCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAG
GTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTC
GAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAG
CCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGT
GGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTG
CCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAG
TACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGAC
TGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCAC
AGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCG
GGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCAC

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000402174_chr22_29383064_+_2550nt
ATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAA
TATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTA
CAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAG
AGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCAC
CGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTT
GTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTC
AACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTG
GAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCAC
CACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGT
CGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATG
GACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGC
AGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGC
AGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTC
AGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTG
CTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCG
GTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCT
GTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTC
ATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCC
CCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAG
GTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTC
GAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAG
CCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGT
GGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTG
CCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAG
TACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGAC
TGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCAC
AGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCG
GGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCAC

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000406323_chr22_29383064_+_2574nt
ATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGTTTTCTTTCCATTTTATTTCCTAGATGCACCCACTGGGCCTATGTAATAAC
AATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGTC
CTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAAC
CAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAAA
GTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTC
TCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTA
GAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCC
ACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTGC
GTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTG
GAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCCA
GCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTCC
CCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCC
TACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTAC
CAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTT
CCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTC
AGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAG
TGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCC
CTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGA
CCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGC
CCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAAT
AGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCG
TGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTC
TACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGACA
GATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACT
GAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATC
CCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGA
GGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGG
CCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCACT


* Fusion transcript sequences (Full-length transcript).
>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000544604_chr22_29383064_+_6564nt
GTTATTCCAGGATCTTTGGAGACCCGAGGAAAGCCGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAA
GGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGGTAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTC
ATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAAC
AGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATG
TGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATG
CCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTG
ACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTC
AGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGA
GCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGG
TCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCA
TAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATT
ACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGA
CCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCC
TGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCA
AGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCAC
CTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGC
CCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAG
GCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGG
GCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCA
GTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACA
GTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACA
GCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCA
GGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAG
CTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCT
TGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGG
CCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCT
GCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAG
GGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGC
GGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCC
TCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAG
CTCAGGAGGAACTCTTACCTGGAAATTGGGAACTGTATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAG
CTTTGACAAACACACAAAAGTGGTAATAAAGAGAGCCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCC
ATTAACAAATCAACAGACAAAATTCTCCGAGTCCTTTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTT
CCGAGGTGTGGGATTGAGTTCTCTGCTTTGTTTTTTTTTAAGATATTGTATGTAAATGTAAAAAGTTATTTAAATATATATTTTAAAGAA
CCCTAACTGCCAACTTTTGCTGAAAAAGAAAAAAAAATCACTGCTGCATTAAATGAACCACATCATGTGTAGATACTGTTGTCTCCCTGA
AGGGAGCTCAGGCCTTTGAAAAGCTCAGGGCTTCACCTGCCTTAGAAAATGAACCAGAAACTTGAAGTAAAGCTAGTTGATAGGGGTACA
GGCTCTGAGGAGCAGTGCAAAACTGCCTCTTTCTTTCTCGTGGCAAATCCCAATGTACACGATTTCAGGTCTCAGACGCCATGCCTCTCC
AGCCCACGCCTTTAGGCAGGTGATGGCAGCAGCTAGGAATAGGGTGTACATGATCCACAGCCCTGCGGAGCCAGGTCAAGCCGCTGCTAT
GAAAGCTCCAGGGTGATGGGGACGATTCTGCCCAGTGTCCTCAGTCTGTCCCCTCAGGTCATGGTCCCAAGTGAAATGACAGAGTTCACA
GCCCTGGTCTTGGCTGAGGTCCAGGTCATAGTAAGGGCATGTTCTTGGGGCCCTCGACCTGAACTCTGACCCTCCGGGCAGGGAAGAGGA
GGTTGTCCCCTTTGGTTGTCCTGGCTTTGGAGTCCTTTGCAAAAATATTTTGGGCCCCCTGCCACTGGCTGCAGAAATGGCTCGACGGGG
TGTGTGGGGACAGACACCCAGAAGGAATGTACTTTTGTGGCCTTGGTGTCCGATGGGGCTGGGGGAGAGTGCTCTCCACTGACCCAGCAG
CACACCCATGTGCAGTGCGCCTGCATCTGTGTGGGGGCAGCCACACCCCTTGGCTGCTGCTTCCTTGGGCTGCCTTTCTGGGGGCATGTG
ACTGGACCTACGAGGTCTGCACTGAGCTCCATTTGAATGATACCTTTCCTATCCCATTTCCCCCACGGAAGCACCGCTTCAGGGTTATTC
AGTCCTCTGCCTCATGGCTGAAATTGCTCATCTCGTCTGCAGATGTCTACTATCCTGTCTACCTAATGCACTATTATGTATTGATTCTCC
ATGAGACAGAGAGAGAGAGAGACTATCAGATAGTTTACACCCAAAGGGTAGGTTTTTGTATATTTTTCCAGCCTTTTTTATTAAGGGGAA
GGGGAGAGTTTAAAAACCCAAACCGTTGTGGTTTTAAGGTGTTTCATTTTTAAAAGGGAGAGAGAATCTATTTAAAGCTATTTCAGATCA
GGGATTGTCATCCTTTTTTGTCCAATGTATTCCTTGTTCTTTAAAAAAATTTTTTTTAGAGGAAACTAATATTAGTCTTTGTGTTCACTA
ACTCTTCTGGTCACTTGTATTTATTTATTCATTCATTCATCAGATATTTGTTGCCATCTGAAAGAACTGGCCCAGTGGGTCTGAAAGCTC
GCTTGAGAATAGGAAACTTGAGACCTGGCCCCCTGTGGGTAGGAGAACAAGGACCACCTGGGTTCTCCAGTCTTGAACGAGAATCTCACT
CTTATCAGAATGTTTTTCTTAACCTCAGCGTATGATGAGGAAATTTACTTATCTCTAGCTAGGATTTGACAAATTCCAACATCAAATGAT
CAAAACATTTGCCACTGAGGCTTCACTGGTGAGATCCGTTCTCCGTCCTCGGGTGCAGTCCCTTGGGGGCTGCTCCTCGGACTGCGCCCC
GCACACCTGTTATCGAGGGTGTGAGAAGCGCCTAAGCTGGTGACATGTGATCTGGGACGCCTTCATTTCTCGGGCCAGGAGTAGCAGCTG
CTAAGGACAGCAGCTTGCATTGCGTGGTTTTAGGGAAGCAGGGTCTGGCTTTTAATATGAACTGCAAAAAGCAGCTTCTCACTGATATTT
TTTTGTTGTTGTTTCTGGGGGGTTTTTTTGTTTTGTTTTTAATGCCTTTGAGTGCATATTTTCTTCCTCGTCTGAAACCGAACTCCCAAA
GTGGCTTTCTTTAGCCCTGGCTGGAAAACCACCTCTCAATAGCCTTAAGCAATAAATAGATGAGTAGAGAATGTGGCTTCAACTGGGCTT
ATTAAAGTAAGTGTGTCTAGTTTTCACTTGAACAAGTGATAGCTGCAGATGGCGAAAGAAACCCATTTAATTTTTGTAGCTTACAGGTGG
TAGAAACAAAAATGCAATTTTAAAACCTTAAATACCAAATACCAACCATTGCCTTTTTTTTTTTTGAGATGGAATTTTGCTCTTGTCACC
CAGGCTGGAGTGCAATGGCGCGATCTCACCTCACTGCAACCTCTGCCTCCCGGGTCCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGC
TGGGATTACAGGCATGCGCCACCACACCCAGCTAATTTTGTATTTTTGGTAGAGACAGGGTATCTCCATGTTGGTCAGGCTGGTCTTGGA
TTCCCGACCTCAGGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCTGCCCAGCAATACCAACC
ATTGTCTTTTAAATTCGTGTTGGCTTCTCAGACAGGGAGATCACTGGAATAAAATAACCGATGGTCTTATTTTGTCACACGTAAATCAAA
AGAAATGTCCTCTTTGAAGTTGTAAGACTCCACCAATGACAGACACCCTTTTCGGTGGACTCTGAGTGGTGTGTAGTGGTTTTATAGCCA
TGGAAACTAGGAGTATCTCACTTTCCACTGAGAACCCCTGCCCCCAATCCCTCTAAGTTGGGGTGTGGCAGTTGGGCAGGGTCAAGTGAC
CCAGCCCTGGCTGTAGGACAGCCATATACAGTGAAGAGTTCTAGAACCAGCTAAAAATGGAAGTTTGGGTGTTTACCAACAAGGTACCTC
TTTATGGATGCAGCCCCAGTAAGCTGGCTTTAACTCTCAGCTCCTTCCCTGTCTCCTCCTAATCCAAGCCCTTTTATAAAATAAAGCCCC
TTCTGTCCCACTGCTCACATACTTATGTGCTGCTAGTCTCTACTCGAAGTTCGTGCAGGACTAATGCTTTTAAAATGAGGTCTAAAAAAT
AATTACTAGTCGAGACTATTATTCTTTAAACAGAACTGCCTTTTTCTACTCTTTATGTAAACTCTTTCTATTGTGTTGGTCTAACAAGGC
ACTATTTTAAAATTTTTTAATTTTTCCCATAGCACTTAAAAGAGATTTTGTAAAGACCTTGCTGTAAAGATTTTGTAATAAAATGGTCTA
AGGGCTCTTTTTCCAACATTACCATTTTTAAAAAATGTTTTAAAAGCTAGAAGACAACTTATGTATATTCTGTATATGTATAGCAGCACA
TTTCATTTATGGAAATATGTTCTCAGAATATTTATTTACTAATATATTTATCTTAAGCCATGTCTTATGTTGAGAGTGTGACATTGTTGG
AATAATCATTGAAAATGACTAACACAAGACCCTGTAAATACATGATAATTGCACACAGATTTTACATATTTGCAGACCAAAAATGATTTA

>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000332811_chr22_29383064_+_6564nt
GTTATTCCAGGATCTTTGGAGACCCGAGGAAAGCCGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAA
GGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGGTAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTC
ATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAAC
AGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATG
TGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATG
CCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTG
ACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTC
AGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGA
GCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGG
TCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCA
TAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATT
ACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGA
CCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCC
TGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCA
AGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCAC
CTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGC
CCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAG
GCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGG
GCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCA
GTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACA
GTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACA
GCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCA
GGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAG
CTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCT
TGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGG
CCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCT
GCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAG
GGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGC
GGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCC
TCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAG
CTCAGGAGGAACTCTTACCTGGAAATTGGGAACTGTATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAG
CTTTGACAAACACACAAAAGTGGTAATAAAGAGAGCCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCC
ATTAACAAATCAACAGACAAAATTCTCCGAGTCCTTTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTT
CCGAGGTGTGGGATTGAGTTCTCTGCTTTGTTTTTTTTTAAGATATTGTATGTAAATGTAAAAAGTTATTTAAATATATATTTTAAAGAA
CCCTAACTGCCAACTTTTGCTGAAAAAGAAAAAAAAATCACTGCTGCATTAAATGAACCACATCATGTGTAGATACTGTTGTCTCCCTGA
AGGGAGCTCAGGCCTTTGAAAAGCTCAGGGCTTCACCTGCCTTAGAAAATGAACCAGAAACTTGAAGTAAAGCTAGTTGATAGGGGTACA
GGCTCTGAGGAGCAGTGCAAAACTGCCTCTTTCTTTCTCGTGGCAAATCCCAATGTACACGATTTCAGGTCTCAGACGCCATGCCTCTCC
AGCCCACGCCTTTAGGCAGGTGATGGCAGCAGCTAGGAATAGGGTGTACATGATCCACAGCCCTGCGGAGCCAGGTCAAGCCGCTGCTAT
GAAAGCTCCAGGGTGATGGGGACGATTCTGCCCAGTGTCCTCAGTCTGTCCCCTCAGGTCATGGTCCCAAGTGAAATGACAGAGTTCACA
GCCCTGGTCTTGGCTGAGGTCCAGGTCATAGTAAGGGCATGTTCTTGGGGCCCTCGACCTGAACTCTGACCCTCCGGGCAGGGAAGAGGA
GGTTGTCCCCTTTGGTTGTCCTGGCTTTGGAGTCCTTTGCAAAAATATTTTGGGCCCCCTGCCACTGGCTGCAGAAATGGCTCGACGGGG
TGTGTGGGGACAGACACCCAGAAGGAATGTACTTTTGTGGCCTTGGTGTCCGATGGGGCTGGGGGAGAGTGCTCTCCACTGACCCAGCAG
CACACCCATGTGCAGTGCGCCTGCATCTGTGTGGGGGCAGCCACACCCCTTGGCTGCTGCTTCCTTGGGCTGCCTTTCTGGGGGCATGTG
ACTGGACCTACGAGGTCTGCACTGAGCTCCATTTGAATGATACCTTTCCTATCCCATTTCCCCCACGGAAGCACCGCTTCAGGGTTATTC
AGTCCTCTGCCTCATGGCTGAAATTGCTCATCTCGTCTGCAGATGTCTACTATCCTGTCTACCTAATGCACTATTATGTATTGATTCTCC
ATGAGACAGAGAGAGAGAGAGACTATCAGATAGTTTACACCCAAAGGGTAGGTTTTTGTATATTTTTCCAGCCTTTTTTATTAAGGGGAA
GGGGAGAGTTTAAAAACCCAAACCGTTGTGGTTTTAAGGTGTTTCATTTTTAAAAGGGAGAGAGAATCTATTTAAAGCTATTTCAGATCA
GGGATTGTCATCCTTTTTTGTCCAATGTATTCCTTGTTCTTTAAAAAAATTTTTTTTAGAGGAAACTAATATTAGTCTTTGTGTTCACTA
ACTCTTCTGGTCACTTGTATTTATTTATTCATTCATTCATCAGATATTTGTTGCCATCTGAAAGAACTGGCCCAGTGGGTCTGAAAGCTC
GCTTGAGAATAGGAAACTTGAGACCTGGCCCCCTGTGGGTAGGAGAACAAGGACCACCTGGGTTCTCCAGTCTTGAACGAGAATCTCACT
CTTATCAGAATGTTTTTCTTAACCTCAGCGTATGATGAGGAAATTTACTTATCTCTAGCTAGGATTTGACAAATTCCAACATCAAATGAT
CAAAACATTTGCCACTGAGGCTTCACTGGTGAGATCCGTTCTCCGTCCTCGGGTGCAGTCCCTTGGGGGCTGCTCCTCGGACTGCGCCCC
GCACACCTGTTATCGAGGGTGTGAGAAGCGCCTAAGCTGGTGACATGTGATCTGGGACGCCTTCATTTCTCGGGCCAGGAGTAGCAGCTG
CTAAGGACAGCAGCTTGCATTGCGTGGTTTTAGGGAAGCAGGGTCTGGCTTTTAATATGAACTGCAAAAAGCAGCTTCTCACTGATATTT
TTTTGTTGTTGTTTCTGGGGGGTTTTTTTGTTTTGTTTTTAATGCCTTTGAGTGCATATTTTCTTCCTCGTCTGAAACCGAACTCCCAAA
GTGGCTTTCTTTAGCCCTGGCTGGAAAACCACCTCTCAATAGCCTTAAGCAATAAATAGATGAGTAGAGAATGTGGCTTCAACTGGGCTT
ATTAAAGTAAGTGTGTCTAGTTTTCACTTGAACAAGTGATAGCTGCAGATGGCGAAAGAAACCCATTTAATTTTTGTAGCTTACAGGTGG
TAGAAACAAAAATGCAATTTTAAAACCTTAAATACCAAATACCAACCATTGCCTTTTTTTTTTTTGAGATGGAATTTTGCTCTTGTCACC
CAGGCTGGAGTGCAATGGCGCGATCTCACCTCACTGCAACCTCTGCCTCCCGGGTCCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGC
TGGGATTACAGGCATGCGCCACCACACCCAGCTAATTTTGTATTTTTGGTAGAGACAGGGTATCTCCATGTTGGTCAGGCTGGTCTTGGA
TTCCCGACCTCAGGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCTGCCCAGCAATACCAACC
ATTGTCTTTTAAATTCGTGTTGGCTTCTCAGACAGGGAGATCACTGGAATAAAATAACCGATGGTCTTATTTTGTCACACGTAAATCAAA
AGAAATGTCCTCTTTGAAGTTGTAAGACTCCACCAATGACAGACACCCTTTTCGGTGGACTCTGAGTGGTGTGTAGTGGTTTTATAGCCA
TGGAAACTAGGAGTATCTCACTTTCCACTGAGAACCCCTGCCCCCAATCCCTCTAAGTTGGGGTGTGGCAGTTGGGCAGGGTCAAGTGAC
CCAGCCCTGGCTGTAGGACAGCCATATACAGTGAAGAGTTCTAGAACCAGCTAAAAATGGAAGTTTGGGTGTTTACCAACAAGGTACCTC
TTTATGGATGCAGCCCCAGTAAGCTGGCTTTAACTCTCAGCTCCTTCCCTGTCTCCTCCTAATCCAAGCCCTTTTATAAAATAAAGCCCC
TTCTGTCCCACTGCTCACATACTTATGTGCTGCTAGTCTCTACTCGAAGTTCGTGCAGGACTAATGCTTTTAAAATGAGGTCTAAAAAAT
AATTACTAGTCGAGACTATTATTCTTTAAACAGAACTGCCTTTTTCTACTCTTTATGTAAACTCTTTCTATTGTGTTGGTCTAACAAGGC
ACTATTTTAAAATTTTTTAATTTTTCCCATAGCACTTAAAAGAGATTTTGTAAAGACCTTGCTGTAAAGATTTTGTAATAAAATGGTCTA
AGGGCTCTTTTTCCAACATTACCATTTTTAAAAAATGTTTTAAAAGCTAGAAGACAACTTATGTATATTCTGTATATGTATAGCAGCACA
TTTCATTTATGGAAATATGTTCTCAGAATATTTATTTACTAATATATTTATCTTAAGCCATGTCTTATGTTGAGAGTGTGACATTGTTGG
AATAATCATTGAAAATGACTAACACAAGACCCTGTAAATACATGATAATTGCACACAGATTTTACATATTTGCAGACCAAAAATGATTTA

>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000402174_chr22_29383064_+_2762nt
GTTATTCCAGGATCTTTGGAGACCCGAGGAAAGCCGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAA
GGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGGTAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTC
ATATCAAGATGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAAC
AGCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATG
TGTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATG
CCATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTG
ACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTC
AGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGA
GCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGG
TCATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCA
TAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATT
ACCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGA
CCATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCC
TGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCA
AGGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCAC
CTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGC
CCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAG
GCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGG
GCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCA
GTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACA
GTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACA
GCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCA
GGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAG
CTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCT
TGTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGG
CCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCT
GCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAG
GGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGC
GGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCC
TCCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAG

>In-frame_ERG_ENST00000398911_chr21_39947586_-_ZNRF3_ENST00000406323_chr22_29383064_+_3041nt
GTTATTCCAGGATCTTTGGAGACCCGAGGAAAGCCGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAA
GGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGGTAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTC
ATATCAAGTGCACCCACTGGGCCTATGTAATAACAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACA
GCCAGAATTGGACCCGAAACCATGCCTCACTGTCCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGT
GTCTGAAAACCCAGAAGCTATTGATCAGCTGAACCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGC
CATTAAGCTGATGAACATCGTCAACAAGCAGAAAGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGA
CATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTCTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCA
GAATTCCATGAACAGGCTGGCTGTGCAGGCTCTAGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAG
CTGTGGGGCCCTGGACACACTCAGCAGCAGCTCCACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGT
CATCCCCTGTACTCACCGGTTTCACAGGAAGTGCGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCAT
AGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTGGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTA
CCCCGGCCGCGTGCACAGGACCAACGCCATCCCAGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGAC
CATGGACCGGCACGGGGAGCAGAGCCTCTATTCCCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCT
GGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCCTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAA
GGCAGCTTGCTTCTCCCAGTATGAGACCATGTACCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACC
TAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTTCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCC
CTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTCAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGG
CAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAGTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGG
CGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCCCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAG
TGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAG
TCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGCCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAG
CAGCAACTCCTCCCTGGAGCACAGGGGGCCCAATAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAG
GAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCGTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGC
TGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTCTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTT
GTACGGCCTTCACCCCGACCATTTGCCCAGGACAGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGC
CCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACTGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTG
CTACCCCGGGGCCCGGGACCTGAGCCAGCGCATCCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGG
GACCCACAGCCTCGGCTCCTGGGGTGGGACGCGAGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCG
GGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGGCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCT
CCAGGACACTCAGGAGTCCAGCACCACTGCCACTGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAGC
TCAGGAGGAACTCTTACCTGGAAATTGGGAACTGTATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAGC
TTTGACAAACACACAAAAGTGGTAATAAAGAGAGCCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCCA
TTAACAAATCAACAGACAAAATTCTCCGAGTCCTTTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTTC

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000544604_chr22_29383064_+_6710nt
GCTGAGCCCGTCGGCGCCGAGGGAGTTAGTGCGACCCGGCTCGGCGCGCACGGCCAAGGCACGCGCGCTGGCACACGCGGGCGCGGACAC
GCGCGGACACACACGTGCGGGACACGCCCTCCCCCGACGGCGGCGCTAACCTCTCGGTTATTCCAGGATCTTTGGAGACCCGAGGAAAGC
CGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAAGGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGG
TAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAA
CAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGT
CCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAA
CCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAA
AGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGT
CTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCT
AGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTC
CACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTG
CGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGT
GGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCC
AGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTC
CCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGC
CTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTA
CCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTT
TCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTT
CAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCA
GTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTC
CCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGG
ACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGG
CCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAA
TAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTC
GTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCT
CTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGAC
AGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACAC
TGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCAT
CCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCG
AGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCG
GCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCAC
TGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAGCTCAGGAGGAACTCTTACCTGGAAATTGGGAACT
GTATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAGCTTTGACAAACACACAAAAGTGGTAATAAAGAGA
GCCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCCATTAACAAATCAACAGACAAAATTCTCCGAGTCC
TTTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTTCCGAGGTGTGGGATTGAGTTCTCTGCTTTGTTTT
TTTTTAAGATATTGTATGTAAATGTAAAAAGTTATTTAAATATATATTTTAAAGAACCCTAACTGCCAACTTTTGCTGAAAAAGAAAAAA
AAATCACTGCTGCATTAAATGAACCACATCATGTGTAGATACTGTTGTCTCCCTGAAGGGAGCTCAGGCCTTTGAAAAGCTCAGGGCTTC
ACCTGCCTTAGAAAATGAACCAGAAACTTGAAGTAAAGCTAGTTGATAGGGGTACAGGCTCTGAGGAGCAGTGCAAAACTGCCTCTTTCT
TTCTCGTGGCAAATCCCAATGTACACGATTTCAGGTCTCAGACGCCATGCCTCTCCAGCCCACGCCTTTAGGCAGGTGATGGCAGCAGCT
AGGAATAGGGTGTACATGATCCACAGCCCTGCGGAGCCAGGTCAAGCCGCTGCTATGAAAGCTCCAGGGTGATGGGGACGATTCTGCCCA
GTGTCCTCAGTCTGTCCCCTCAGGTCATGGTCCCAAGTGAAATGACAGAGTTCACAGCCCTGGTCTTGGCTGAGGTCCAGGTCATAGTAA
GGGCATGTTCTTGGGGCCCTCGACCTGAACTCTGACCCTCCGGGCAGGGAAGAGGAGGTTGTCCCCTTTGGTTGTCCTGGCTTTGGAGTC
CTTTGCAAAAATATTTTGGGCCCCCTGCCACTGGCTGCAGAAATGGCTCGACGGGGTGTGTGGGGACAGACACCCAGAAGGAATGTACTT
TTGTGGCCTTGGTGTCCGATGGGGCTGGGGGAGAGTGCTCTCCACTGACCCAGCAGCACACCCATGTGCAGTGCGCCTGCATCTGTGTGG
GGGCAGCCACACCCCTTGGCTGCTGCTTCCTTGGGCTGCCTTTCTGGGGGCATGTGACTGGACCTACGAGGTCTGCACTGAGCTCCATTT
GAATGATACCTTTCCTATCCCATTTCCCCCACGGAAGCACCGCTTCAGGGTTATTCAGTCCTCTGCCTCATGGCTGAAATTGCTCATCTC
GTCTGCAGATGTCTACTATCCTGTCTACCTAATGCACTATTATGTATTGATTCTCCATGAGACAGAGAGAGAGAGAGACTATCAGATAGT
TTACACCCAAAGGGTAGGTTTTTGTATATTTTTCCAGCCTTTTTTATTAAGGGGAAGGGGAGAGTTTAAAAACCCAAACCGTTGTGGTTT
TAAGGTGTTTCATTTTTAAAAGGGAGAGAGAATCTATTTAAAGCTATTTCAGATCAGGGATTGTCATCCTTTTTTGTCCAATGTATTCCT
TGTTCTTTAAAAAAATTTTTTTTAGAGGAAACTAATATTAGTCTTTGTGTTCACTAACTCTTCTGGTCACTTGTATTTATTTATTCATTC
ATTCATCAGATATTTGTTGCCATCTGAAAGAACTGGCCCAGTGGGTCTGAAAGCTCGCTTGAGAATAGGAAACTTGAGACCTGGCCCCCT
GTGGGTAGGAGAACAAGGACCACCTGGGTTCTCCAGTCTTGAACGAGAATCTCACTCTTATCAGAATGTTTTTCTTAACCTCAGCGTATG
ATGAGGAAATTTACTTATCTCTAGCTAGGATTTGACAAATTCCAACATCAAATGATCAAAACATTTGCCACTGAGGCTTCACTGGTGAGA
TCCGTTCTCCGTCCTCGGGTGCAGTCCCTTGGGGGCTGCTCCTCGGACTGCGCCCCGCACACCTGTTATCGAGGGTGTGAGAAGCGCCTA
AGCTGGTGACATGTGATCTGGGACGCCTTCATTTCTCGGGCCAGGAGTAGCAGCTGCTAAGGACAGCAGCTTGCATTGCGTGGTTTTAGG
GAAGCAGGGTCTGGCTTTTAATATGAACTGCAAAAAGCAGCTTCTCACTGATATTTTTTTGTTGTTGTTTCTGGGGGGTTTTTTTGTTTT
GTTTTTAATGCCTTTGAGTGCATATTTTCTTCCTCGTCTGAAACCGAACTCCCAAAGTGGCTTTCTTTAGCCCTGGCTGGAAAACCACCT
CTCAATAGCCTTAAGCAATAAATAGATGAGTAGAGAATGTGGCTTCAACTGGGCTTATTAAAGTAAGTGTGTCTAGTTTTCACTTGAACA
AGTGATAGCTGCAGATGGCGAAAGAAACCCATTTAATTTTTGTAGCTTACAGGTGGTAGAAACAAAAATGCAATTTTAAAACCTTAAATA
CCAAATACCAACCATTGCCTTTTTTTTTTTTGAGATGGAATTTTGCTCTTGTCACCCAGGCTGGAGTGCAATGGCGCGATCTCACCTCAC
TGCAACCTCTGCCTCCCGGGTCCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCGCCACCACACCCAGCTA
ATTTTGTATTTTTGGTAGAGACAGGGTATCTCCATGTTGGTCAGGCTGGTCTTGGATTCCCGACCTCAGGTGATCCGCCCACCTCGGCCT
CCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCTGCCCAGCAATACCAACCATTGTCTTTTAAATTCGTGTTGGCTTCTCAGACA
GGGAGATCACTGGAATAAAATAACCGATGGTCTTATTTTGTCACACGTAAATCAAAAGAAATGTCCTCTTTGAAGTTGTAAGACTCCACC
AATGACAGACACCCTTTTCGGTGGACTCTGAGTGGTGTGTAGTGGTTTTATAGCCATGGAAACTAGGAGTATCTCACTTTCCACTGAGAA
CCCCTGCCCCCAATCCCTCTAAGTTGGGGTGTGGCAGTTGGGCAGGGTCAAGTGACCCAGCCCTGGCTGTAGGACAGCCATATACAGTGA
AGAGTTCTAGAACCAGCTAAAAATGGAAGTTTGGGTGTTTACCAACAAGGTACCTCTTTATGGATGCAGCCCCAGTAAGCTGGCTTTAAC
TCTCAGCTCCTTCCCTGTCTCCTCCTAATCCAAGCCCTTTTATAAAATAAAGCCCCTTCTGTCCCACTGCTCACATACTTATGTGCTGCT
AGTCTCTACTCGAAGTTCGTGCAGGACTAATGCTTTTAAAATGAGGTCTAAAAAATAATTACTAGTCGAGACTATTATTCTTTAAACAGA
ACTGCCTTTTTCTACTCTTTATGTAAACTCTTTCTATTGTGTTGGTCTAACAAGGCACTATTTTAAAATTTTTTAATTTTTCCCATAGCA
CTTAAAAGAGATTTTGTAAAGACCTTGCTGTAAAGATTTTGTAATAAAATGGTCTAAGGGCTCTTTTTCCAACATTACCATTTTTAAAAA
ATGTTTTAAAAGCTAGAAGACAACTTATGTATATTCTGTATATGTATAGCAGCACATTTCATTTATGGAAATATGTTCTCAGAATATTTA
TTTACTAATATATTTATCTTAAGCCATGTCTTATGTTGAGAGTGTGACATTGTTGGAATAATCATTGAAAATGACTAACACAAGACCCTG
TAAATACATGATAATTGCACACAGATTTTACATATTTGCAGACCAAAAATGATTTAAAACAAGTTGTAGTCTTCTATGGTTTTGTAACAA

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000332811_chr22_29383064_+_6710nt
GCTGAGCCCGTCGGCGCCGAGGGAGTTAGTGCGACCCGGCTCGGCGCGCACGGCCAAGGCACGCGCGCTGGCACACGCGGGCGCGGACAC
GCGCGGACACACACGTGCGGGACACGCCCTCCCCCGACGGCGGCGCTAACCTCTCGGTTATTCCAGGATCTTTGGAGACCCGAGGAAAGC
CGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAAGGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGG
TAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAA
CAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGT
CCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAA
CCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAA
AGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGT
CTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCT
AGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTC
CACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTG
CGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGT
GGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCC
AGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTC
CCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGC
CTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTA
CCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTT
TCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTT
CAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCA
GTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTC
CCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGG
ACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGG
CCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAA
TAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTC
GTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCT
CTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGAC
AGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACAC
TGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCAT
CCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCG
AGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCG
GCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCAC
TGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAGCTCAGGAGGAACTCTTACCTGGAAATTGGGAACT
GTATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAGCTTTGACAAACACACAAAAGTGGTAATAAAGAGA
GCCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCCATTAACAAATCAACAGACAAAATTCTCCGAGTCC
TTTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTTCCGAGGTGTGGGATTGAGTTCTCTGCTTTGTTTT
TTTTTAAGATATTGTATGTAAATGTAAAAAGTTATTTAAATATATATTTTAAAGAACCCTAACTGCCAACTTTTGCTGAAAAAGAAAAAA
AAATCACTGCTGCATTAAATGAACCACATCATGTGTAGATACTGTTGTCTCCCTGAAGGGAGCTCAGGCCTTTGAAAAGCTCAGGGCTTC
ACCTGCCTTAGAAAATGAACCAGAAACTTGAAGTAAAGCTAGTTGATAGGGGTACAGGCTCTGAGGAGCAGTGCAAAACTGCCTCTTTCT
TTCTCGTGGCAAATCCCAATGTACACGATTTCAGGTCTCAGACGCCATGCCTCTCCAGCCCACGCCTTTAGGCAGGTGATGGCAGCAGCT
AGGAATAGGGTGTACATGATCCACAGCCCTGCGGAGCCAGGTCAAGCCGCTGCTATGAAAGCTCCAGGGTGATGGGGACGATTCTGCCCA
GTGTCCTCAGTCTGTCCCCTCAGGTCATGGTCCCAAGTGAAATGACAGAGTTCACAGCCCTGGTCTTGGCTGAGGTCCAGGTCATAGTAA
GGGCATGTTCTTGGGGCCCTCGACCTGAACTCTGACCCTCCGGGCAGGGAAGAGGAGGTTGTCCCCTTTGGTTGTCCTGGCTTTGGAGTC
CTTTGCAAAAATATTTTGGGCCCCCTGCCACTGGCTGCAGAAATGGCTCGACGGGGTGTGTGGGGACAGACACCCAGAAGGAATGTACTT
TTGTGGCCTTGGTGTCCGATGGGGCTGGGGGAGAGTGCTCTCCACTGACCCAGCAGCACACCCATGTGCAGTGCGCCTGCATCTGTGTGG
GGGCAGCCACACCCCTTGGCTGCTGCTTCCTTGGGCTGCCTTTCTGGGGGCATGTGACTGGACCTACGAGGTCTGCACTGAGCTCCATTT
GAATGATACCTTTCCTATCCCATTTCCCCCACGGAAGCACCGCTTCAGGGTTATTCAGTCCTCTGCCTCATGGCTGAAATTGCTCATCTC
GTCTGCAGATGTCTACTATCCTGTCTACCTAATGCACTATTATGTATTGATTCTCCATGAGACAGAGAGAGAGAGAGACTATCAGATAGT
TTACACCCAAAGGGTAGGTTTTTGTATATTTTTCCAGCCTTTTTTATTAAGGGGAAGGGGAGAGTTTAAAAACCCAAACCGTTGTGGTTT
TAAGGTGTTTCATTTTTAAAAGGGAGAGAGAATCTATTTAAAGCTATTTCAGATCAGGGATTGTCATCCTTTTTTGTCCAATGTATTCCT
TGTTCTTTAAAAAAATTTTTTTTAGAGGAAACTAATATTAGTCTTTGTGTTCACTAACTCTTCTGGTCACTTGTATTTATTTATTCATTC
ATTCATCAGATATTTGTTGCCATCTGAAAGAACTGGCCCAGTGGGTCTGAAAGCTCGCTTGAGAATAGGAAACTTGAGACCTGGCCCCCT
GTGGGTAGGAGAACAAGGACCACCTGGGTTCTCCAGTCTTGAACGAGAATCTCACTCTTATCAGAATGTTTTTCTTAACCTCAGCGTATG
ATGAGGAAATTTACTTATCTCTAGCTAGGATTTGACAAATTCCAACATCAAATGATCAAAACATTTGCCACTGAGGCTTCACTGGTGAGA
TCCGTTCTCCGTCCTCGGGTGCAGTCCCTTGGGGGCTGCTCCTCGGACTGCGCCCCGCACACCTGTTATCGAGGGTGTGAGAAGCGCCTA
AGCTGGTGACATGTGATCTGGGACGCCTTCATTTCTCGGGCCAGGAGTAGCAGCTGCTAAGGACAGCAGCTTGCATTGCGTGGTTTTAGG
GAAGCAGGGTCTGGCTTTTAATATGAACTGCAAAAAGCAGCTTCTCACTGATATTTTTTTGTTGTTGTTTCTGGGGGGTTTTTTTGTTTT
GTTTTTAATGCCTTTGAGTGCATATTTTCTTCCTCGTCTGAAACCGAACTCCCAAAGTGGCTTTCTTTAGCCCTGGCTGGAAAACCACCT
CTCAATAGCCTTAAGCAATAAATAGATGAGTAGAGAATGTGGCTTCAACTGGGCTTATTAAAGTAAGTGTGTCTAGTTTTCACTTGAACA
AGTGATAGCTGCAGATGGCGAAAGAAACCCATTTAATTTTTGTAGCTTACAGGTGGTAGAAACAAAAATGCAATTTTAAAACCTTAAATA
CCAAATACCAACCATTGCCTTTTTTTTTTTTGAGATGGAATTTTGCTCTTGTCACCCAGGCTGGAGTGCAATGGCGCGATCTCACCTCAC
TGCAACCTCTGCCTCCCGGGTCCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCGCCACCACACCCAGCTA
ATTTTGTATTTTTGGTAGAGACAGGGTATCTCCATGTTGGTCAGGCTGGTCTTGGATTCCCGACCTCAGGTGATCCGCCCACCTCGGCCT
CCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCTGCCCAGCAATACCAACCATTGTCTTTTAAATTCGTGTTGGCTTCTCAGACA
GGGAGATCACTGGAATAAAATAACCGATGGTCTTATTTTGTCACACGTAAATCAAAAGAAATGTCCTCTTTGAAGTTGTAAGACTCCACC
AATGACAGACACCCTTTTCGGTGGACTCTGAGTGGTGTGTAGTGGTTTTATAGCCATGGAAACTAGGAGTATCTCACTTTCCACTGAGAA
CCCCTGCCCCCAATCCCTCTAAGTTGGGGTGTGGCAGTTGGGCAGGGTCAAGTGACCCAGCCCTGGCTGTAGGACAGCCATATACAGTGA
AGAGTTCTAGAACCAGCTAAAAATGGAAGTTTGGGTGTTTACCAACAAGGTACCTCTTTATGGATGCAGCCCCAGTAAGCTGGCTTTAAC
TCTCAGCTCCTTCCCTGTCTCCTCCTAATCCAAGCCCTTTTATAAAATAAAGCCCCTTCTGTCCCACTGCTCACATACTTATGTGCTGCT
AGTCTCTACTCGAAGTTCGTGCAGGACTAATGCTTTTAAAATGAGGTCTAAAAAATAATTACTAGTCGAGACTATTATTCTTTAAACAGA
ACTGCCTTTTTCTACTCTTTATGTAAACTCTTTCTATTGTGTTGGTCTAACAAGGCACTATTTTAAAATTTTTTAATTTTTCCCATAGCA
CTTAAAAGAGATTTTGTAAAGACCTTGCTGTAAAGATTTTGTAATAAAATGGTCTAAGGGCTCTTTTTCCAACATTACCATTTTTAAAAA
ATGTTTTAAAAGCTAGAAGACAACTTATGTATATTCTGTATATGTATAGCAGCACATTTCATTTATGGAAATATGTTCTCAGAATATTTA
TTTACTAATATATTTATCTTAAGCCATGTCTTATGTTGAGAGTGTGACATTGTTGGAATAATCATTGAAAATGACTAACACAAGACCCTG
TAAATACATGATAATTGCACACAGATTTTACATATTTGCAGACCAAAAATGATTTAAAACAAGTTGTAGTCTTCTATGGTTTTGTAACAA

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000402174_chr22_29383064_+_2908nt
GCTGAGCCCGTCGGCGCCGAGGGAGTTAGTGCGACCCGGCTCGGCGCGCACGGCCAAGGCACGCGCGCTGGCACACGCGGGCGCGGACAC
GCGCGGACACACACGTGCGGGACACGCCCTCCCCCGACGGCGGCGCTAACCTCTCGGTTATTCCAGGATCTTTGGAGACCCGAGGAAAGC
CGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAAGGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGG
TAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGATGCACCCACTGGGCCTATGTAATAA
CAATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGT
CCTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAA
CCAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAA
AGTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGT
CTCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCT
AGAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTC
CACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTG
CGTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGT
GGAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCC
AGCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTC
CCCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGC
CTACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTA
CCAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTT
TCCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTT
CAGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCA
GTGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTC
CCTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGG
ACCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGG
CCCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAA
TAGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTC
GTGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCT
CTACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGAC
AGATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACAC
TGAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCAT
CCCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCG
AGGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCG
GCCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCAC
TGAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAGCTCAGGAGGAACTCTTACCTGGAAATTGGGAACT

>In-frame_ERG_ENST00000398919_chr21_39947586_-_ZNRF3_ENST00000406323_chr22_29383064_+_3187nt
GCTGAGCCCGTCGGCGCCGAGGGAGTTAGTGCGACCCGGCTCGGCGCGCACGGCCAAGGCACGCGCGCTGGCACACGCGGGCGCGGACAC
GCGCGGACACACACGTGCGGGACACGCCCTCCCCCGACGGCGGCGCTAACCTCTCGGTTATTCCAGGATCTTTGGAGACCCGAGGAAAGC
CGTGTTGACCAAAAGCAAGACAAATGACTCACAGAGAAAAAAGATGGCAGAACCAAGGGCAACTAAAGCCGTCAGGTTCTGAACAGCTGG
TAGATGGGCTGGCTTACTGAAGGACATGATTCAGACTGTCCCGGACCCAGCAGCTCATATCAAGTGCACCCACTGGGCCTATGTAATAAC
AATGACGAAGAGGACTTGTATGAATATGGCTGGGTAGGAGTGGTGAAGCTGGAACAGCCAGAATTGGACCCGAAACCATGCCTCACTGTC
CTAGGCAAGGCCAAGCGAGCAGTACAGCGGGGAGCTACTGCAGTCATCTTTGATGTGTCTGAAAACCCAGAAGCTATTGATCAGCTGAAC
CAGGGCTCTGAAGACCCGCTCAAGAGGCCGGTGGTGTATGTGAAGGGTGCAGATGCCATTAAGCTGATGAACATCGTCAACAAGCAGAAA
GTGGCTCGAGCAAGGATCCAGCACCGCCCTCCTCGACAACCCACTGAATACTTTGACATGGGGATTTTCCTGGCTTTCTTCGTCGTGGTC
TCCTTGGTCTGCCTCATCCTCCTTGTCAAAATCAAGCTGAAGCAGCGACGCAGTCAGAATTCCATGAACAGGCTGGCTGTGCAGGCTCTA
GAGAAGATGGAAACCAGAAAGTTCAACTCCAAGAGCAAGGGGCGCCGGGAGGGGAGCTGTGGGGCCCTGGACACACTCAGCAGCAGCTCC
ACGTCCGACTGTGCCATCTGTCTGGAGAAGTACATTGATGGAGAGGAGCTGCGGGTCATCCCCTGTACTCACCGGTTTCACAGGAAGTGC
GTGGACCCCTGGCTGCTGCAGCACCACACCTGCCCCCACTGTCGGCACAACATCATAGAACAAAAGGGAAACCCAAGCGCGGTGTGTGTG
GAGACCAGCAACCTCTCACGTGGTCGGCAGCAGAGGGTGACCCTGCCGGTGCATTACCCCGGCCGCGTGCACAGGACCAACGCCATCCCA
GCCTACCCTACGAGGACAAGCATGGACTCCCACGGCAACCCCGTCACCTTGCTGACCATGGACCGGCACGGGGAGCAGAGCCTCTATTCC
CCGCAGACCCCCGCCTACATCCGCAGCTACCCACCCCTCCACCTGGACCACAGCCTGGCCGCTCACCGCTGCGGCCTGGAGCACCGGGCC
TACTCCCCAGCCCACCCCTTCCGCAGGCCCAAGTTGAGTGGCCGCAGCTTCTCCAAGGCAGCTTGCTTCTCCCAGTATGAGACCATGTAC
CAGCACTACTACTTCCAGGGCCTCAGCTACCCGGAGCAGGAGGGGCAGTCCCCACCTAGCCTCGCACCCCGGGGCCCGGCCCGTGCCTTT
CCTCCGAGCGGCAGTGGCAGCCTGCTCTTCCCCACCGTGGTGCACGTGGCCCCGCCCTCCCACCTGGAGAGCGGCAGCACGTCCAGCTTC
AGCTGCTATCACGGCCACCGCTCGGTGTGCAGTGGCTACCTGGCCGACTGCCCAGGCAGCGACAGCAGCAGCAGCAGCAGCTCCGGCCAG
TGCCACTGTTCCTCCAGTGACTCTGTGGTAGACTGCACTGAGGTCAGCAACCAGGGCGTGTACGGGAGCTGCTCCACCTTCCGCAGCTCC
CTCAGCAGCGACTATGACCCCTTCATCTACCGCAGCCGGAGCCCCTGTCGTGCCAGTGAGGCGGGGGGCTCGGGCAGCTCGGGCCGGGGA
CCTGCCCTGTGCTTCGAGGGCTCCCCGCCTCCCGAGGAGCTCCCGGCGGTGCACAGTCATGGTGCTGGGCGGGGCGAGCCTTGGCCGGGC
CCTGCCTCTCCCTCGGGGGATCAGGTGTCCACCTGCAGCCTGGAGATGAACTACAGCAGCAACTCCTCCCTGGAGCACAGGGGGCCCAAT
AGCTCTACCTCAGAAGTGGGGCTCGAGGCTTCTCCTGGGGCCGCCCCTGACCTCAGGAGGACCTGGAAGGGGGGCCACGAGTTGCCGTCG
TGTGCCTGCTGCTGCGAGCCCCAGCCCTCCCCAGCCGGGCCTAGCGCCGGAGCAGCTGGCAGCAGCACCTTGTTCCTGGGGCCCCACCTC
TACGAGGGCTCTGGCCCGGCGGGTGGGGAGCCCCAGTCAGGAAGCTCCCAGGGCTTGTACGGCCTTCACCCCGACCATTTGCCCAGGACA
GATGGGGTGAAATACGAGGGTCTGCCCTGCTGCTTCTATGAAGAGAAGCAGGTGGCCCGCGGGGGCGGAGGGGGCAGCGGCTGCTACACT
GAGGACTACTCGGTGAGTGTGCAGTACACGCTCACCGAGGAACCACCGCCCGGCTGCTACCCCGGGGCCCGGGACCTGAGCCAGCGCATC
CCCATCATTCCAGAGGATGTGGACTGTGATCTGGGCCTGCCCTCGGACTGCCAAGGGACCCACAGCCTCGGCTCCTGGGGTGGGACGCGA
GGCCCGGATACCCCACGGCCCCACAGGGGCCTGGGAGCAACCCGGGAAGAGGAGCGGGCTCTGTGCTGCCAGGCTAGGGCCCTACTGCGG
CCTGGCTGCCCTCCGGAGGAGGCGGGTGCTGTCAGGGCCAACTTCCCTAGTGCCCTCCAGGACACTCAGGAGTCCAGCACCACTGCCACT
GAGGCTGCAGGACCGAGATCTCACTCAGCAGACAGCAGCAGCCCGGGAGCCTGAGCTCAGGAGGAACTCTTACCTGGAAATTGGGAACTG
TATGGAGACTCCAAACTGACTTCTTTCAAAAAACAAAAACAAAAAATTTTTTTAGCTTTGACAAACACACAAAAGTGGTAATAAAGAGAG
CCCTCCTTGTCAACCCAAAATGTGAGCCCCCTGTGGCAAAACCACCCCCTACCCCATTAACAAATCAACAGACAAAATTCTCCGAGTCCT
TTGCCTCTTTTGATAACATGTTGTTCTGTTTTGTAAAGTGTGTGTGCTTGGGGTTCCGAGGTGTGGGATTGAGTTCTCTGCTTTGTTTTT


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FusionGenePPI for ERG_ZNRF3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ERGJUN, ETS2, AR, HSPA4, HSPA8, NEDD4, PRKDC, XRCC5, XRCC6, PARP1, XRCC4, NME1, DDX3X, PCBP1, HNRNPA2B1, DDX5, TRIM21, TPM1, HNRNPM, EIF2S1, RPLP0, PRPF8, RPL7A, HNRNPDL, TUBB, CAD, ACTB, ATP5A1, RPS18, HNRNPU, SPTAN1, DNAJA1, DNAJA2, DNAJA4, APP, USP9X, ADAR, CDC5L, CLTC, DDX21, DDX23, DKC1, EEF1A2, ELAVL1, FBL, HNRNPA1, HNRNPAB, HNRNPC, HNRNPD, HNRNPF, HNRNPH1, HNRNPH3, HNRNPUL1, HNRNPUL2, HSPD1, ILF2, ILF3, LANCL1, MATR3, NCL, NOLC1, NONO, NPM1, NUMA1, POLR2A, PRPF40A, PUF60, RCC2, SF3B1, SF3B2, SF3B3, SFPQ, SNRNP200, SYN1, TOP1, TOP2B, XRN2, CUL3, SPOP, TRIM25, UBR5, TRIM33, RING1, UBR4, RNF2, TRIP12, HUWE1, STUB1, UHRF1, HERC2, BRD4, BRD2, BRD3ZNRF3UBE2N, FZD4, RSPO1, LGR4, LRP6, GFI1B, DVL2, HSPB1, RSPO2, RSPO3, LGR5, FZD7


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ERG_ZNRF3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ERG_ZNRF3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneERGC0033578Prostatic Neoplasms5CTD_human
HgeneERGC0023418leukemia1CTD_human
HgeneERGC0023467Leukemia, Myelocytic, Acute1CTD_human
HgeneERGC1961102Precursor Cell Lymphoblastic Leukemia Lymphoma1CTD_human
TgeneZNRF3C0030297Pancreatic Neoplasm2CTD_human
TgeneZNRF3C0206686Adrenocortical carcinoma1CTD_human