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Fusion gene ID: 11543 |
FusionGeneSummary for EML1_GPI |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: EML1_GPI | Fusion gene ID: 11543 | Hgene | Tgene | Gene symbol | EML1 | GPI | Gene ID | 2009 | 10007 |
| Gene name | echinoderm microtubule associated protein like 1 | glucosamine-6-phosphate deaminase 1 | |
| Synonyms | BH|ELP79|EMAP|EMAPL|HuEMAP | GNP1|GNPDA|GNPI|GPI|HLN | |
| Cytomap | 14q32.2 | 5q31.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | echinoderm microtubule-associated protein-like 1EMAP-1huEMAP-1 | glucosamine-6-phosphate isomerase 1GNPDA 1glcN6P deaminase 1oscillin | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O00423 | P06744 | |
| Ensembl transtripts involved in fusion gene | ENST00000327921, ENST00000262233, ENST00000334192, ENST00000556758, | ENST00000415930, ENST00000356487, ENST00000586425, | |
| Fusion gene scores | * DoF score | 9 X 4 X 7=252 | 9 X 6 X 7=378 |
| # samples | 9 | 10 | |
| ** MAII score | log2(9/252*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/378*10)=-1.91838623444635 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: EML1 [Title/Abstract] AND GPI [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-RN-AAAQ-01A | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| TCGA | LD | SARC | TCGA-RN-AAAQ-01A | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000327921 | ENST00000415930 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| intron-3CDS | ENST00000327921 | ENST00000356487 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| intron-3CDS | ENST00000327921 | ENST00000586425 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| Frame-shift | ENST00000262233 | ENST00000415930 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| Frame-shift | ENST00000262233 | ENST00000356487 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| Frame-shift | ENST00000262233 | ENST00000586425 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| Frame-shift | ENST00000334192 | ENST00000415930 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| Frame-shift | ENST00000334192 | ENST00000356487 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| Frame-shift | ENST00000334192 | ENST00000586425 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| intron-3CDS | ENST00000556758 | ENST00000415930 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| intron-3CDS | ENST00000556758 | ENST00000356487 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| intron-3CDS | ENST00000556758 | ENST00000586425 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884153 | + |
| intron-3CDS | ENST00000327921 | ENST00000415930 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| intron-3CDS | ENST00000327921 | ENST00000356487 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| intron-3CDS | ENST00000327921 | ENST00000586425 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| In-frame | ENST00000262233 | ENST00000415930 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| In-frame | ENST00000262233 | ENST00000356487 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| In-frame | ENST00000262233 | ENST00000586425 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| In-frame | ENST00000334192 | ENST00000415930 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| In-frame | ENST00000334192 | ENST00000356487 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| In-frame | ENST00000334192 | ENST00000586425 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| intron-3CDS | ENST00000556758 | ENST00000415930 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| intron-3CDS | ENST00000556758 | ENST00000356487 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
| intron-3CDS | ENST00000556758 | ENST00000586425 | EML1 | chr14 | 100259880 | + | GPI | chr19 | 34884633 | + |
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FusionProtFeatures for EML1_GPI |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| EML1 | GPI |
| Modulates the assembly and organization of themicrotubule cytoskeleton, and probably plays a role in regulatingthe orientation of the mitotic spindle and the orientation of theplane of cell division. Required for normal proliferation ofneuronal progenitor cells in the developing brain and for normalbrain development. Does not affect neuron migration per se.{ECO:0000250|UniProtKB:Q05BC3}. | Besides it's role as a glycolytic enzyme, mammalian GPIcan function as a tumor-secreted cytokine and an angiogenic factor(AMF) that stimulates endothelial cell motility. GPI is also aneurotrophic factor (Neuroleukin) for spinal and sensory neurons.{ECO:0000269|PubMed:11004567, ECO:0000269|PubMed:11437381}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for EML1_GPI |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_EML1_ENST00000262233_chr14_100259880_+_GPI_ENST00000415930_chr19_34884633_+_293aa MEDGFSSYSSLYDTSSLLQFCNGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGD MESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEAR KELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVT >In-frame_EML1_ENST00000262233_chr14_100259880_+_GPI_ENST00000356487_chr19_34884633_+_293aa MEDGFSSYSSLYDTSSLLQFCNGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGD MESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEAR KELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVT >In-frame_EML1_ENST00000262233_chr14_100259880_+_GPI_ENST00000586425_chr19_34884633_+_209aa MEDGFSSYSSLYDTSSLLQFCNGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGD MESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEAR >In-frame_EML1_ENST00000334192_chr14_100259880_+_GPI_ENST00000415930_chr19_34884633_+_293aa MEDGFSSYSSLYDTSSLLQFCNGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGD MESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEAR KELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVT >In-frame_EML1_ENST00000334192_chr14_100259880_+_GPI_ENST00000356487_chr19_34884633_+_293aa MEDGFSSYSSLYDTSSLLQFCNGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGD MESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEAR KELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVT >In-frame_EML1_ENST00000334192_chr14_100259880_+_GPI_ENST00000586425_chr19_34884633_+_209aa MEDGFSSYSSLYDTSSLLQFCNGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGD MESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMRGKSTEEAR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_EML1_ENST00000262233_chr14_100259880_+_GPI_ENST00000415930_chr19_34884633_+_879nt ATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCTCGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTG CTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGACGCCCCTGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGG TACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCCCTATGACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGAC ATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCGTGTGGACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAAT GGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAAGATGATACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATA CGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTTGGCCCAGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGA AAGGAGCTCCAGGCTGCGGGCAAGAGTCCAGAGGACCTTGAGAGGCTGCTGCCACATAAGGTCTTTGAAGGAAATCGCCCAACCAACTCT ATTGTGTTCACCAAGCTCACACCATTCATGCTTGGAGCCTTGGTCGCCATGTATGAGCACAAGATCTTCGTTCAGGGCATCATCTGGGAC ATCAACAGCTTTGACCAGTGGGGAGTGGAGCTGGGAAAGCAGCTGGCTAAGAAAATAGAGCCTGAGCTTGATGGCAGTGCTCAAGTGACC >In-frame_EML1_ENST00000262233_chr14_100259880_+_GPI_ENST00000356487_chr19_34884633_+_879nt ATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCTCGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTG CTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGACGCCCCTGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGG TACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCCCTATGACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGAC ATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCGTGTGGACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAAT GGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAAGATGATACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATA CGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTTGGCCCAGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGA AAGGAGCTCCAGGCTGCGGGCAAGAGTCCAGAGGACCTTGAGAGGCTGCTGCCACATAAGGTCTTTGAAGGAAATCGCCCAACCAACTCT ATTGTGTTCACCAAGCTCACACCATTCATGCTTGGAGCCTTGGTCGCCATGTATGAGCACAAGATCTTCGTTCAGGGCATCATCTGGGAC ATCAACAGCTTTGACCAGTGGGGAGTGGAGCTGGGAAAGCAGCTGGCTAAGAAAATAGAGCCTGAGCTTGATGGCAGTGCTCAAGTGACC >In-frame_EML1_ENST00000262233_chr14_100259880_+_GPI_ENST00000586425_chr19_34884633_+_627nt ATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCTCGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTG CTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGACGCCCCTGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGG TACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCCCTATGACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGAC ATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCGTGTGGACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAAT GGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAAGATGATACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATA CGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTTGGCCCAGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGA >In-frame_EML1_ENST00000334192_chr14_100259880_+_GPI_ENST00000415930_chr19_34884633_+_879nt ATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCTCGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTG CTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGACGCCCCTGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGG TACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCCCTATGACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGAC ATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCGTGTGGACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAAT GGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAAGATGATACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATA CGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTTGGCCCAGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGA AAGGAGCTCCAGGCTGCGGGCAAGAGTCCAGAGGACCTTGAGAGGCTGCTGCCACATAAGGTCTTTGAAGGAAATCGCCCAACCAACTCT ATTGTGTTCACCAAGCTCACACCATTCATGCTTGGAGCCTTGGTCGCCATGTATGAGCACAAGATCTTCGTTCAGGGCATCATCTGGGAC ATCAACAGCTTTGACCAGTGGGGAGTGGAGCTGGGAAAGCAGCTGGCTAAGAAAATAGAGCCTGAGCTTGATGGCAGTGCTCAAGTGACC >In-frame_EML1_ENST00000334192_chr14_100259880_+_GPI_ENST00000356487_chr19_34884633_+_879nt ATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCTCGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTG CTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGACGCCCCTGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGG TACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCCCTATGACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGAC ATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCGTGTGGACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAAT GGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAAGATGATACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATA CGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTTGGCCCAGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGA AAGGAGCTCCAGGCTGCGGGCAAGAGTCCAGAGGACCTTGAGAGGCTGCTGCCACATAAGGTCTTTGAAGGAAATCGCCCAACCAACTCT ATTGTGTTCACCAAGCTCACACCATTCATGCTTGGAGCCTTGGTCGCCATGTATGAGCACAAGATCTTCGTTCAGGGCATCATCTGGGAC ATCAACAGCTTTGACCAGTGGGGAGTGGAGCTGGGAAAGCAGCTGGCTAAGAAAATAGAGCCTGAGCTTGATGGCAGTGCTCAAGTGACC >In-frame_EML1_ENST00000334192_chr14_100259880_+_GPI_ENST00000586425_chr19_34884633_+_627nt ATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCTCGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTG CTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGACGCCCCTGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGG TACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCCCTATGACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGAC ATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCGTGTGGACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAAT GGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAAGATGATACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATA CGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTTGGCCCAGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_EML1_ENST00000262233_chr14_100259880_+_GPI_ENST00000415930_chr19_34884633_+_3138nt ATGGTAACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCG GCGGCGGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACAC GTCCTCGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTGCTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGAC GCCCCTGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGGTACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCC CTATGACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGACATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCG TGTGGACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAATGGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAA GATGATACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATACGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTT GGCCCAGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGAAAGGAGCTCCAGGCTGCGGGCAAGAGTCCAGAGGACCTTGA GAGGCTGCTGCCACATAAGGTCTTTGAAGGAAATCGCCCAACCAACTCTATTGTGTTCACCAAGCTCACACCATTCATGCTTGGAGCCTT GGTCGCCATGTATGAGCACAAGATCTTCGTTCAGGGCATCATCTGGGACATCAACAGCTTTGACCAGTGGGGAGTGGAGCTGGGAAAGCA GCTGGCTAAGAAAATAGAGCCTGAGCTTGATGGCAGTGCTCAAGTGACCTCTCACGACGCTTCTACCAATGGGCTCATCAACTTCATCAA GCAGCAGCGCGAGGCCAGAGTCCAATAAACTCGTGCTCATCTGCAGCCTCCTCTGTGACTCCCCTTTCTCTTCTCGTCCCTCCTCCCCGG AGCCGGCACTGCATGTTCCTGGACACCACCCAGAGCACCCTCTGGTTGTGGGCTTGGACCACGAGCCCTTAGCAGGGAAGGCTGGTCTCC CCCAGCCTAACCCCCAGCCCCTCCATGTCTATGCTCCCTCTGTGTTAGAATTGGCTGAAGTGTTTTTGTGCAGCTGACTTTTCTGACCCA TGTTCACGTTGTTCACATCCCATGTAGAAAAATAAAGATGCCACGGAGGAGGTTGTAGGCTCAGCCTCTGATTTTTTTTTTCCTGTGATG GTGCTTTATGTAGCAGAGGGCAGGAGCGCTCAGCAGGACGCAGGCTGTGCCTCTGCGGACACTTAACACTAAGTGGTGAGCGGGTCTAGA GTGGAGCAAGGTGCCCTGAGAAGACAATAGTGGGGTGGGGGCACAATCAGTCAGGACGGCAACTTGGCCTGTGTCACCAAATCCCAAGAC TGTTTTCCACTCCTCACCTCTGTGACTGCAGAAATTGGATACTCTGTTCACTCGATGGTTCTAAAAACTGCATTGAGATTATGTTTGTTT CGGGTGAATTCCTGGACAAGACCGAGGATGACTGCCATCTCCTGGCAAGACGCTCAGGTAGTTCTTTTGCTTTAAAAGGCAGATATTGAA AACTGGAATTTTTTTTTTTTGAGTCTCGCTCTGTCACCCAGACTGGAGTGCAGTGGTGCAATCTCGGCTCACTGCAACCTCCGCCTCCCG GGTTCAAGCTATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACACGGCGCACACCACCATACCCAGCTAATTTTTGTATTTTTAGT AGTGAAGGGGTTTTACCATGTTGGGCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTGCCCGCCTCAGCCTCCCACAGTGCTGGGAT TACAGGTATGAGCCACCACGCCCGGCCCATTTTTTTTTTTTTTTTGACAACTTTTTTTTTTTTTTGAGACAGGGTCTTGTTCCATTGCCC AGACTGGAGTGCAGTGGCATGATCACAGCTCACTGCAGCCAGTAATCCTCTTGCCTCAGCCTCCCAAGTAGTTGAGACTACAGGTTGTAC CACTATGCCCTGCTAGTTTTTTCATTTTTTGTAGAGAGACGGGTCTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAAGCTGGA GTGCAGTAGCACGGTCTCAGCTCATTGCAAGCTCCGCCTCCCAGGTTCACGCCATTCTCCTGCCTCAGACTCCTGTGTAGCTGGGAGTAC AGGCACCTGCCACCATGCCCGGCTAATTTTTTATATATTTTTTTAGCAGAGACAGTGTCTCACTGTGTTAGTCAGGATGGTCTCGATCTC CTGACCTCGTGATCCGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCAAGGCGGGTCTTGCTGTGT TTCCCAGACTAGACTGGTCTTGAATTCCAGGGCTCAAGAGATCTCCCACCTCAGCCTCCCACAGTGCTGGGATTACAGGCGTGAGCCGCC ACACCCAGCCTATTCAAAATTTTTTTTTCTTAGAGACAGGGTCTTTGTTGCCCAGGCTGGACTGCAGTGATACAATCATAGCTGACTGAA GCCTCAAATTCCCAGGCTAAGGTGATCTTCTCACCTCAGCCTTCCAAGTAGCTGGGTCCGCAGATGCATGCCAGTACACCCAGCTCATTT AAAAAAAAATTTTTTTCTTTTTTGAGAGTCTTGCTTTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGCAAGCTCCACC TCCCGGCTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGCCCGCCACCACACCCGGCTAATTTTTTGTATTT TTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTTGATCTCCTGACCTCATGATCCGCCTGCTTTGGCCTCCCAAAGTGCTGG >In-frame_EML1_ENST00000262233_chr14_100259880_+_GPI_ENST00000356487_chr19_34884633_+_1310nt ATGGTAACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCG GCGGCGGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACAC GTCCTCGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTGCTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGAC GCCCCTGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGGTACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCC CTATGACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGACATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCG TGTGGACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAATGGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAA GATGATACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATACGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTT GGCCCAGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGAAAGGAGCTCCAGGCTGCGGGCAAGAGTCCAGAGGACCTTGA GAGGCTGCTGCCACATAAGGTCTTTGAAGGAAATCGCCCAACCAACTCTATTGTGTTCACCAAGCTCACACCATTCATGCTTGGAGCCTT GGTCGCCATGTATGAGCACAAGATCTTCGTTCAGGGCATCATCTGGGACATCAACAGCTTTGACCAGTGGGGAGTGGAGCTGGGAAAGCA GCTGGCTAAGAAAATAGAGCCTGAGCTTGATGGCAGTGCTCAAGTGACCTCTCACGACGCTTCTACCAATGGGCTCATCAACTTCATCAA GCAGCAGCGCGAGGCCAGAGTCCAATAAACTCGTGCTCATCTGCAGCCTCCTCTGTGACTCCCCTTTCTCTTCTCGTCCCTCCTCCCCGG AGCCGGCACTGCATGTTCCTGGACACCACCCAGAGCACCCTCTGGTTGTGGGCTTGGACCACGAGCCCTTAGCAGGGAAGGCTGGTCTCC CCCAGCCTAACCCCCAGCCCCTCCATGTCTATGCTCCCTCTGTGTTAGAATTGGCTGAAGTGTTTTTGTGCAGCTGACTTTTCTGACCCA >In-frame_EML1_ENST00000262233_chr14_100259880_+_GPI_ENST00000586425_chr19_34884633_+_1115nt ATGGTAACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCG GCGGCGGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACAC GTCCTCGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTGCTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGAC GCCCCTGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGGTACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCC CTATGACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGACATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCG TGTGGACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAATGGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAA GATGATACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATACGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTT GGCCCAGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGAAAGGAGCTCCAGGCTGCGGGCAAGAGTCCAGAGGACCTTGA GAGGCTGCTGCCACATAAGAGTGGAGCTGGGAAAGCAGCTGGCTAAGAAAATAGAGCCTGAGCTTGATGGCAGTGCTCAAGTGACCTCTC ACGACGCTTCTACCAATGGGCTCATCAACTTCATCAAGCAGCAGCGCGAGGCCAGAGTCCAATAAACTCGTGCTCATCTGCAGCCTCCTC TGTGACTCCCCTTTCTCTTCTCGTCCCTCCTCCCCGGAGCCGGCACTGCATGTTCCTGGACACCACCCAGAGCACCCTCTGGTTGTGGGC TTGGACCACGAGCCCTTAGCAGGGAAGGCTGGTCTCCCCCAGCCTAACCCCCAGCCCCTCCATGTCTATGCTCCCTCTGTGTTAGAATTG >In-frame_EML1_ENST00000334192_chr14_100259880_+_GPI_ENST00000415930_chr19_34884633_+_3133nt AACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCGGCGGC GGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCT CGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTGCTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGACGCCCC TGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGGTACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCCCTATG ACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGACATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCGTGTGG ACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAATGGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAAGATGA TACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATACGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTTGGCCC AGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGAAAGGAGCTCCAGGCTGCGGGCAAGAGTCCAGAGGACCTTGAGAGGC TGCTGCCACATAAGGTCTTTGAAGGAAATCGCCCAACCAACTCTATTGTGTTCACCAAGCTCACACCATTCATGCTTGGAGCCTTGGTCG CCATGTATGAGCACAAGATCTTCGTTCAGGGCATCATCTGGGACATCAACAGCTTTGACCAGTGGGGAGTGGAGCTGGGAAAGCAGCTGG CTAAGAAAATAGAGCCTGAGCTTGATGGCAGTGCTCAAGTGACCTCTCACGACGCTTCTACCAATGGGCTCATCAACTTCATCAAGCAGC AGCGCGAGGCCAGAGTCCAATAAACTCGTGCTCATCTGCAGCCTCCTCTGTGACTCCCCTTTCTCTTCTCGTCCCTCCTCCCCGGAGCCG GCACTGCATGTTCCTGGACACCACCCAGAGCACCCTCTGGTTGTGGGCTTGGACCACGAGCCCTTAGCAGGGAAGGCTGGTCTCCCCCAG CCTAACCCCCAGCCCCTCCATGTCTATGCTCCCTCTGTGTTAGAATTGGCTGAAGTGTTTTTGTGCAGCTGACTTTTCTGACCCATGTTC ACGTTGTTCACATCCCATGTAGAAAAATAAAGATGCCACGGAGGAGGTTGTAGGCTCAGCCTCTGATTTTTTTTTTCCTGTGATGGTGCT TTATGTAGCAGAGGGCAGGAGCGCTCAGCAGGACGCAGGCTGTGCCTCTGCGGACACTTAACACTAAGTGGTGAGCGGGTCTAGAGTGGA GCAAGGTGCCCTGAGAAGACAATAGTGGGGTGGGGGCACAATCAGTCAGGACGGCAACTTGGCCTGTGTCACCAAATCCCAAGACTGTTT TCCACTCCTCACCTCTGTGACTGCAGAAATTGGATACTCTGTTCACTCGATGGTTCTAAAAACTGCATTGAGATTATGTTTGTTTCGGGT GAATTCCTGGACAAGACCGAGGATGACTGCCATCTCCTGGCAAGACGCTCAGGTAGTTCTTTTGCTTTAAAAGGCAGATATTGAAAACTG GAATTTTTTTTTTTTGAGTCTCGCTCTGTCACCCAGACTGGAGTGCAGTGGTGCAATCTCGGCTCACTGCAACCTCCGCCTCCCGGGTTC AAGCTATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACACGGCGCACACCACCATACCCAGCTAATTTTTGTATTTTTAGTAGTGA AGGGGTTTTACCATGTTGGGCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTGCCCGCCTCAGCCTCCCACAGTGCTGGGATTACAG GTATGAGCCACCACGCCCGGCCCATTTTTTTTTTTTTTTTGACAACTTTTTTTTTTTTTTGAGACAGGGTCTTGTTCCATTGCCCAGACT GGAGTGCAGTGGCATGATCACAGCTCACTGCAGCCAGTAATCCTCTTGCCTCAGCCTCCCAAGTAGTTGAGACTACAGGTTGTACCACTA TGCCCTGCTAGTTTTTTCATTTTTTGTAGAGAGACGGGTCTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAAGCTGGAGTGCA GTAGCACGGTCTCAGCTCATTGCAAGCTCCGCCTCCCAGGTTCACGCCATTCTCCTGCCTCAGACTCCTGTGTAGCTGGGAGTACAGGCA CCTGCCACCATGCCCGGCTAATTTTTTATATATTTTTTTAGCAGAGACAGTGTCTCACTGTGTTAGTCAGGATGGTCTCGATCTCCTGAC CTCGTGATCCGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCAAGGCGGGTCTTGCTGTGTTTCCC AGACTAGACTGGTCTTGAATTCCAGGGCTCAAGAGATCTCCCACCTCAGCCTCCCACAGTGCTGGGATTACAGGCGTGAGCCGCCACACC CAGCCTATTCAAAATTTTTTTTTCTTAGAGACAGGGTCTTTGTTGCCCAGGCTGGACTGCAGTGATACAATCATAGCTGACTGAAGCCTC AAATTCCCAGGCTAAGGTGATCTTCTCACCTCAGCCTTCCAAGTAGCTGGGTCCGCAGATGCATGCCAGTACACCCAGCTCATTTAAAAA AAAATTTTTTTCTTTTTTGAGAGTCTTGCTTTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGCAAGCTCCACCTCCCG GCTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGCCCGCCACCACACCCGGCTAATTTTTTGTATTTTTAGT AGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTTGATCTCCTGACCTCATGATCCGCCTGCTTTGGCCTCCCAAAGTGCTGGGATTA >In-frame_EML1_ENST00000334192_chr14_100259880_+_GPI_ENST00000356487_chr19_34884633_+_1305nt AACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCGGCGGC GGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCT CGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTGCTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGACGCCCC TGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGGTACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCCCTATG ACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGACATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCGTGTGG ACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAATGGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAAGATGA TACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATACGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTTGGCCC AGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGAAAGGAGCTCCAGGCTGCGGGCAAGAGTCCAGAGGACCTTGAGAGGC TGCTGCCACATAAGGTCTTTGAAGGAAATCGCCCAACCAACTCTATTGTGTTCACCAAGCTCACACCATTCATGCTTGGAGCCTTGGTCG CCATGTATGAGCACAAGATCTTCGTTCAGGGCATCATCTGGGACATCAACAGCTTTGACCAGTGGGGAGTGGAGCTGGGAAAGCAGCTGG CTAAGAAAATAGAGCCTGAGCTTGATGGCAGTGCTCAAGTGACCTCTCACGACGCTTCTACCAATGGGCTCATCAACTTCATCAAGCAGC AGCGCGAGGCCAGAGTCCAATAAACTCGTGCTCATCTGCAGCCTCCTCTGTGACTCCCCTTTCTCTTCTCGTCCCTCCTCCCCGGAGCCG GCACTGCATGTTCCTGGACACCACCCAGAGCACCCTCTGGTTGTGGGCTTGGACCACGAGCCCTTAGCAGGGAAGGCTGGTCTCCCCCAG CCTAACCCCCAGCCCCTCCATGTCTATGCTCCCTCTGTGTTAGAATTGGCTGAAGTGTTTTTGTGCAGCTGACTTTTCTGACCCATGTTC >In-frame_EML1_ENST00000334192_chr14_100259880_+_GPI_ENST00000586425_chr19_34884633_+_1110nt AACCGGCAGCAGCAGCCGCCACAGCAGGGCCGGCCCCAGCGCCAGCGCCGGTCGCGGTCGGGCTCAGCTCAGTGTGTGGTGAGCGGCGGC GGCGCGGCCGGGCCGGGGAGCGGGCGCGGCCCGGCGGCCTCAGCATGGAGGACGGCTTCTCCAGCTACAGCAGCCTGTACGACACGTCCT CGCTGCTCCAGTTCTGCAACGGTTTTGACAACTTCGAGCAGCTGCTCTCGGGGGCTCACTGGATGGACCAGCACTTCCGCACGACGCCCC TGGAGAAGAACGCCCCCGTCTTGCTGGCCCTGCTGGGTATCTGGTACATCAACTGCTTTGGGTGTGAGACACACGCCATGCTGCCCTATG ACCAGTACCTGCACCGCTTTGCTGCGTACTTCCAGCAGGGCGACATGGAGTCCAATGGGAAATACATCACCAAATCTGGAACCCGTGTGG ACCACCAGACAGGCCCCATTGTGTGGGGGGAGCCAGGGACCAATGGCCAGCATGCTTTTTACCAGCTCATCCACCAAGGCACCAAGATGA TACCCTGTGACTTCCTCATCCCGGTCCAGACCCAGCACCCCATACGGAAGGGTCTGCATCACAAGATCCTCCTGGCCAACTTCTTGGCCC AGACAGAGGCCCTGATGAGGGGAAAATCGACGGAGGAGGCCCGAAAGGAGCTCCAGGCTGCGGGCAAGAGTCCAGAGGACCTTGAGAGGC TGCTGCCACATAAGAGTGGAGCTGGGAAAGCAGCTGGCTAAGAAAATAGAGCCTGAGCTTGATGGCAGTGCTCAAGTGACCTCTCACGAC GCTTCTACCAATGGGCTCATCAACTTCATCAAGCAGCAGCGCGAGGCCAGAGTCCAATAAACTCGTGCTCATCTGCAGCCTCCTCTGTGA CTCCCCTTTCTCTTCTCGTCCCTCCTCCCCGGAGCCGGCACTGCATGTTCCTGGACACCACCCAGAGCACCCTCTGGTTGTGGGCTTGGA CCACGAGCCCTTAGCAGGGAAGGCTGGTCTCCCCCAGCCTAACCCCCAGCCCCTCCATGTCTATGCTCCCTCTGTGTTAGAATTGGCTGA 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FusionGenePPI for EML1_GPI |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| EML1 | ISG20L2, DCUN1D1, TUBA1B, TUBB3, TUBB2A, TUBB2B, DCTN1, EML1, TUBA1A, FBXO28, EML4, TUBB | GPI | PARP14, PCNA, ISG15, CCP110, NEURL4, CDK2, TPI1, TMEM256, ENO3, PDCD6IP, BAG3, ASB15, AMFR, HUWE1, FUS, CUL7, OBSL1, ALDH4A1, ANXA7, DCXR, FH, ABAT, AKR1A1, ENO1, ESD, GOT2, LACTB2, MRPL45, PGM1, PGM5, PRDX6, RAB10, SDHB, SORD, TKT, WDR1, PEF1, NTRK1, SPICE1, PPME1, TAMM41, SPRYD4, ADCK2, U2AF2, PA2G4, ANXA5, UBE2N, NANS, TRAP1, SND1, PLS3, SNRPB2, EIF5B, PPA1, HPRT1, IDH2, PDIA3, MRPL12, CRNN, ZNF207, CPNE3, CS, FOXA1, BRCA1, TES |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for EML1_GPI |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | GPI | P06744 | DB11638 | Artenimol | Glucose-6-phosphate isomerase | small molecule | approved|investigational |
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RelatedDiseases for EML1_GPI |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | EML1 | C1838239 | Band Heterotopia of Brain | 1 | UNIPROT |
| Tgene | GPI | C3150730 | HEMOLYTIC ANEMIA, NONSPHEROCYTIC, DUE TO GLUCOSE PHOSPHATE ISOMERASE DEFICIENCY | 6 | CTD_human;ORPHANET;UNIPROT |
| Tgene | GPI | C0002878 | Anemia, Hemolytic | 1 | CTD_human |
| Tgene | GPI | C1458155 | Mammary Neoplasms | 1 | CTD_human |
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