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Fusion gene ID: 11386 |
FusionGeneSummary for ELAVL1_ATXN10 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ELAVL1_ATXN10 | Fusion gene ID: 11386 | Hgene | Tgene | Gene symbol | ELAVL1 | ATXN10 | Gene ID | 1994 | 25814 |
| Gene name | ELAV like RNA binding protein 1 | ataxin 10 | |
| Synonyms | ELAV1|HUR|Hua|MelG | E46L|HUMEEP|SCA10 | |
| Cytomap | 19p13.2 | 22q13.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ELAV-like protein 1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)Hu antigen Rembryonic lethal, abnormal vision, drosophila, homolog-like 1hu-antigen R | ataxin-10brain protein E46 homologspinocerebellar ataxia type 10 protein | |
| Modification date | 20180527 | 20180522 | |
| UniProtAcc | Q15717 | Q9UBB4 | |
| Ensembl transtripts involved in fusion gene | ENST00000407627, ENST00000596459, ENST00000351593, ENST00000593807, | ENST00000381061, ENST00000252934, ENST00000498009, ENST00000402380, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 7 X 5 X 7=245 |
| # samples | 1 | 8 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(8/245*10)=-1.61470984411521 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ELAVL1 [Title/Abstract] AND ATXN10 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ELAVL1 | GO:0045727 | positive regulation of translation | 21613615 |
| Hgene | ELAVL1 | GO:0048255 | mRNA stabilization | 21613615 |
| Hgene | ELAVL1 | GO:0051260 | protein homooligomerization | 26595526 |
| Hgene | ELAVL1 | GO:0070935 | 3'-UTR-mediated mRNA stabilization | 14517288 |
| Tgene | ATXN10 | GO:0031175 | neuron projection development | 16498633 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | UCS | TCGA-ND-A4WF-01A | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000407627 | ENST00000381061 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| Frame-shift | ENST00000407627 | ENST00000252934 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| 5CDS-intron | ENST00000407627 | ENST00000498009 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| 5CDS-intron | ENST00000407627 | ENST00000402380 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| Frame-shift | ENST00000596459 | ENST00000381061 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| Frame-shift | ENST00000596459 | ENST00000252934 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| 5CDS-intron | ENST00000596459 | ENST00000498009 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| 5CDS-intron | ENST00000596459 | ENST00000402380 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| In-frame | ENST00000351593 | ENST00000381061 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| In-frame | ENST00000351593 | ENST00000252934 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| 5CDS-intron | ENST00000351593 | ENST00000498009 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| 5CDS-intron | ENST00000351593 | ENST00000402380 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| Frame-shift | ENST00000593807 | ENST00000381061 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| Frame-shift | ENST00000593807 | ENST00000252934 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| 5CDS-intron | ENST00000593807 | ENST00000498009 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
| 5CDS-intron | ENST00000593807 | ENST00000402380 | ELAVL1 | chr19 | 8038609 | - | ATXN10 | chr22 | 46238871 | + |
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FusionProtFeatures for ELAVL1_ATXN10 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ELAVL1 | ATXN10 |
| RNA-binding protein that binds to the 3'-UTR region ofmRNAs and increases their stability (PubMed:14517288,PubMed:18285462). Involved in embryonic stem cells (ESCs)differentiation: preferentially binds mRNAs that are notmethylated by N6-methyladenosine (m6A), stabilizing them,promoting ESCs differentiation (By similarity). Binds to poly-Uelements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs(PubMed:8626503, PubMed:17632515, PubMed:18285462,PubMed:23519412). Binds avidly to the AU-rich element in FOS andIL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element,binds to a core element of 27 nucleotides that contain AUUUA,AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro (PubMed:8626503). With ZNF385A,binds the 3'-UTR of p53/TP53 mRNA to control their nuclear exportinduced by CDKN2A. Hence, may regulate p53/TP53 expression andmediate in part the CDKN2A anti-proliferative activity. May alsobind with ZNF385A the CCNB1 mRNA (By similarity).{ECO:0000250|UniProtKB:P70372, ECO:0000269|PubMed:14517288,ECO:0000269|PubMed:17632515, ECO:0000269|PubMed:18285462,ECO:0000269|PubMed:19029303, ECO:0000269|PubMed:23519412,ECO:0000269|PubMed:8626503}. | Necessary for the survival of cerebellar neurons.Induces neuritogenesis by activating the Ras-MAP kinase pathway.May play a role in the maintenance of a critical intracellularglycosylation level and homeostasis. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for ELAVL1_ATXN10 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ELAVL1_ENST00000351593_chr19_8038609_-_ATXN10_ENST00000381061_chr22_46238871_+_234aa MGSGGRSAQVSTGQRAWLLPCRFLKNTMSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGY GFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTVLTQWVIYAI >In-frame_ELAVL1_ENST00000351593_chr19_8038609_-_ATXN10_ENST00000252934_chr22_46238871_+_234aa MGSGGRSAQVSTGQRAWLLPCRFLKNTMSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGY GFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTVLTQWVIYAI |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ELAVL1_ENST00000351593_chr19_8038609_-_ATXN10_ENST00000381061_chr22_46238871_+_702nt ATGGGTAGTGGTGGCAGGAGTGCTCAGGTGTCCACTGGGCAGAGGGCTTGGCTGTTACCCTGCAGATTTTTGAAAAATACAATGTCTAAT GGTTATGAAGACCACATGGCCGAAGACTGCAGGGGTGACATCGGGAGAACGAATTTGATCGTCAACTACCTCCCTCAGAACATGACCCAG GATGAGTTACGAAGCCTGTTCAGCAGCATTGGTGAAGTTGAATCTGCAAAACTTATTCGGGATAAAGTAGCAGGACACAGCTTGGGCTAT GGCTTTGTGAACTACGTGACCGCGAAGGATGCAGAGAGAGCGATCAACACGCTGAACGGCTTGAGGCTCCAGTCAAAAACCATTAAGGTG TCGTATGCTCGCCCGAGCTCAGAGGTGATCAAAGACGCCAACTTGTACATCAGCGGGCTCCCGCGGACCATGACCCAGAAGGACGTAGAA GACATGTTCTCTCGGTTTGGGCGGATCATCAACTCGCGGGTCCTCGTGGATCAGACTACAGTTCTGACCCAGTGGGTGATATATGCCATC CGAAACCTTACCGAAGACAACAGCCAAAACCAAGATTTGATTGCAAAGATGGAGGAACAGGGGCTGGCAGATGCATCCCTACTTAAAAAA >In-frame_ELAVL1_ENST00000351593_chr19_8038609_-_ATXN10_ENST00000252934_chr22_46238871_+_702nt ATGGGTAGTGGTGGCAGGAGTGCTCAGGTGTCCACTGGGCAGAGGGCTTGGCTGTTACCCTGCAGATTTTTGAAAAATACAATGTCTAAT GGTTATGAAGACCACATGGCCGAAGACTGCAGGGGTGACATCGGGAGAACGAATTTGATCGTCAACTACCTCCCTCAGAACATGACCCAG GATGAGTTACGAAGCCTGTTCAGCAGCATTGGTGAAGTTGAATCTGCAAAACTTATTCGGGATAAAGTAGCAGGACACAGCTTGGGCTAT GGCTTTGTGAACTACGTGACCGCGAAGGATGCAGAGAGAGCGATCAACACGCTGAACGGCTTGAGGCTCCAGTCAAAAACCATTAAGGTG TCGTATGCTCGCCCGAGCTCAGAGGTGATCAAAGACGCCAACTTGTACATCAGCGGGCTCCCGCGGACCATGACCCAGAAGGACGTAGAA GACATGTTCTCTCGGTTTGGGCGGATCATCAACTCGCGGGTCCTCGTGGATCAGACTACAGTTCTGACCCAGTGGGTGATATATGCCATC CGAAACCTTACCGAAGACAACAGCCAAAACCAAGATTTGATTGCAAAGATGGAGGAACAGGGGCTGGCAGATGCATCCCTACTTAAAAAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ELAVL1_ENST00000351593_chr19_8038609_-_ATXN10_ENST00000381061_chr22_46238871_+_2422nt AAGCCCGGAGGTGGGAACATCGCAGTGTTCAGAGAACATCGTGTGTTCAAAGAACCACGTGGGTTCTTTAGGGACAAGAAGGCTGAGATG GGTAGTGGTGGCAGGAGTGCTCAGGTGTCCACTGGGCAGAGGGCTTGGCTGTTACCCTGCAGATTTTTGAAAAATACAATGTCTAATGGT TATGAAGACCACATGGCCGAAGACTGCAGGGGTGACATCGGGAGAACGAATTTGATCGTCAACTACCTCCCTCAGAACATGACCCAGGAT GAGTTACGAAGCCTGTTCAGCAGCATTGGTGAAGTTGAATCTGCAAAACTTATTCGGGATAAAGTAGCAGGACACAGCTTGGGCTATGGC TTTGTGAACTACGTGACCGCGAAGGATGCAGAGAGAGCGATCAACACGCTGAACGGCTTGAGGCTCCAGTCAAAAACCATTAAGGTGTCG TATGCTCGCCCGAGCTCAGAGGTGATCAAAGACGCCAACTTGTACATCAGCGGGCTCCCGCGGACCATGACCCAGAAGGACGTAGAAGAC ATGTTCTCTCGGTTTGGGCGGATCATCAACTCGCGGGTCCTCGTGGATCAGACTACAGTTCTGACCCAGTGGGTGATATATGCCATCCGA AACCTTACCGAAGACAACAGCCAAAACCAAGATTTGATTGCAAAGATGGAGGAACAGGGGCTGGCAGATGCATCCCTACTTAAAAAAGTG GGTTTTGAAGTTGAAAAGAAAGGCGAAAAGCTGATCCTGAAATCTACTAGAGACACCCCTAAGCCATGAATGAACTACATCCAAATACCT GAATTTTTGGAATCTGTTTCATGGATTTTTCATCTTCTACCGTATGTGAAATTGCAAGTGTTTGAAGATTTATAAGTACAAATTTGGGAA CATACAAATCTTTTAGGTAGTAGAGTTTAACGTGTATAAGCTAAAAGTGAAAGTAACTGAGTGTTCTCTTGTTTCTTTGCATTAATGTAA CTGTGTGGTTTGCCTTTGTCCCCCTGGATAGAACGTGCATTTAAAGAATATATTGTACTTACTGTGACAGCAGATAATAAACCAGTCTCT TGGAGGGCACAACCCTTATTTGACAAAACTTGGATGTTGGCTTGACTGTGTTTGTCCCTTCAGATGGCAAGTCAGCATCATTCTTTATAT TCCTCTTCTCATTGGGTTTTCTGAACTCTGGCAGGCGGTTGAAGTAGTTTCTCACTGTGATTAATTCTAGCAATCTCTTTTCACCCCTCT GCCTTTCCAAAACATTGACAAGACTCATTTCCAGTTAATTAATTCGAGAACCCTCCCTCTTCATTTTGGGTACTGGGCTGTCTTGTCACT GAGCCCTATCCCTTTGGAATGTGGCAGGGAGTGAGGTTGGTGAGAGAACATGTGGGCACTTAACTCTTCATGTTCCAGTTCATCCCAGAA GTAGACATCCCAGGACCCATTCTGTGTCAAGGTGAATGCCTGTGTCCTCCCCAGCTTCATGCCTCTGTCATGGGGGAAGGAATAGCTTAT GTTCTGCTCTGGTGCAGTGCCGTAGATTAAAGGTACATTTCTATCTTCTTTGATTTAAAAAGCACCAGTCTCATAAAGGTGCCACTCAGT TTTAGCCATGTCTTCACTGAAATTGCAAAAGTACTTTTAGGGAGCAGGAGTTTATTTGACATCTAGTTATCTGTCTGTCTGTTCATCTAT CTATCTGTCTGCTGTATGAGAGGTAGGACTGGATTAAATGACCACTGAACTCACTGAATCCAGATCATTCATATCATCAACAAAAGCTCT AGGGGGAGGTCACGTTGTGAATGCTTAAAACATATTATTTTCTTCAACAACCATATCGCTAAACTAATATATCCAGAGATTTTGCACAAT TCGTGTTGAACCTTCCAAAACAAAAATAAAGACCTGTCCAAAAGTTTTGACAAAAATACTGATTGCTCCCAAATAAAGTGCTTCTAAGCT TTGTGTAGACATAGTTTAACTGATTTGTAAAAATAGCTTAAGCATGTTGAGAATGAAGTAAAAGTTTTCCCATGTGCTGTCTAATGTACT CTGTGTAACTCTGAAGACACATCAGCTTCTAGGATTGCAGCAATCTATGAATAACATTTTTTCTCTCATTTATGACTTTCCATCAGTAAA GAAGCCATTGCAGAATTTAAAATTACACAAAGGAGTCATTCTCTCCTGGGACATAAAGAGTTAAAGCTCTGTCCTCTAAATAGAAGCCTG GCCAAAGGGAGAAAACAGTGGGAGTCCCTTTTCCCTTTTAACAAGTTTGCAATAGACACTTCTTTTTTTCCTGTCTCAATGGATGTGTGC >In-frame_ELAVL1_ENST00000351593_chr19_8038609_-_ATXN10_ENST00000252934_chr22_46238871_+_2425nt AAGCCCGGAGGTGGGAACATCGCAGTGTTCAGAGAACATCGTGTGTTCAAAGAACCACGTGGGTTCTTTAGGGACAAGAAGGCTGAGATG GGTAGTGGTGGCAGGAGTGCTCAGGTGTCCACTGGGCAGAGGGCTTGGCTGTTACCCTGCAGATTTTTGAAAAATACAATGTCTAATGGT TATGAAGACCACATGGCCGAAGACTGCAGGGGTGACATCGGGAGAACGAATTTGATCGTCAACTACCTCCCTCAGAACATGACCCAGGAT GAGTTACGAAGCCTGTTCAGCAGCATTGGTGAAGTTGAATCTGCAAAACTTATTCGGGATAAAGTAGCAGGACACAGCTTGGGCTATGGC TTTGTGAACTACGTGACCGCGAAGGATGCAGAGAGAGCGATCAACACGCTGAACGGCTTGAGGCTCCAGTCAAAAACCATTAAGGTGTCG TATGCTCGCCCGAGCTCAGAGGTGATCAAAGACGCCAACTTGTACATCAGCGGGCTCCCGCGGACCATGACCCAGAAGGACGTAGAAGAC ATGTTCTCTCGGTTTGGGCGGATCATCAACTCGCGGGTCCTCGTGGATCAGACTACAGTTCTGACCCAGTGGGTGATATATGCCATCCGA AACCTTACCGAAGACAACAGCCAAAACCAAGATTTGATTGCAAAGATGGAGGAACAGGGGCTGGCAGATGCATCCCTACTTAAAAAAGTG GGTTTTGAAGTTGAAAAGAAAGGCGAAAAGCTGATCCTGAAATCTACTAGAGACACCCCTAAGCCATGAATGAACTACATCCAAATACCT GAATTTTTGGAATCTGTTTCATGGATTTTTCATCTTCTACCGTATGTGAAATTGCAAGTGTTTGAAGATTTATAAGTACAAATTTGGGAA CATACAAATCTTTTAGGTAGTAGAGTTTAACGTGTATAAGCTAAAAGTGAAAGTAACTGAGTGTTCTCTTGTTTCTTTGCATTAATGTAA CTGTGTGGTTTGCCTTTGTCCCCCTGGATAGAACGTGCATTTAAAGAATATATTGTACTTACTGTGACAGCAGATAATAAACCAGTCTCT TGGAGGGCACAACCCTTATTTGACAAAACTTGGATGTTGGCTTGACTGTGTTTGTCCCTTCAGATGGCAAGTCAGCATCATTCTTTATAT TCCTCTTCTCATTGGGTTTTCTGAACTCTGGCAGGCGGTTGAAGTAGTTTCTCACTGTGATTAATTCTAGCAATCTCTTTTCACCCCTCT GCCTTTCCAAAACATTGACAAGACTCATTTCCAGTTAATTAATTCGAGAACCCTCCCTCTTCATTTTGGGTACTGGGCTGTCTTGTCACT GAGCCCTATCCCTTTGGAATGTGGCAGGGAGTGAGGTTGGTGAGAGAACATGTGGGCACTTAACTCTTCATGTTCCAGTTCATCCCAGAA GTAGACATCCCAGGACCCATTCTGTGTCAAGGTGAATGCCTGTGTCCTCCCCAGCTTCATGCCTCTGTCATGGGGGAAGGAATAGCTTAT GTTCTGCTCTGGTGCAGTGCCGTAGATTAAAGGTACATTTCTATCTTCTTTGATTTAAAAAGCACCAGTCTCATAAAGGTGCCACTCAGT TTTAGCCATGTCTTCACTGAAATTGCAAAAGTACTTTTAGGGAGCAGGAGTTTATTTGACATCTAGTTATCTGTCTGTCTGTTCATCTAT CTATCTGTCTGCTGTATGAGAGGTAGGACTGGATTAAATGACCACTGAACTCACTGAATCCAGATCATTCATATCATCAACAAAAGCTCT AGGGGGAGGTCACGTTGTGAATGCTTAAAACATATTATTTTCTTCAACAACCATATCGCTAAACTAATATATCCAGAGATTTTGCACAAT TCGTGTTGAACCTTCCAAAACAAAAATAAAGACCTGTCCAAAAGTTTTGACAAAAATACTGATTGCTCCCAAATAAAGTGCTTCTAAGCT TTGTGTAGACATAGTTTAACTGATTTGTAAAAATAGCTTAAGCATGTTGAGAATGAAGTAAAAGTTTTCCCATGTGCTGTCTAATGTACT CTGTGTAACTCTGAAGACACATCAGCTTCTAGGATTGCAGCAATCTATGAATAACATTTTTTCTCTCATTTATGACTTTCCATCAGTAAA GAAGCCATTGCAGAATTTAAAATTACACAAAGGAGTCATTCTCTCCTGGGACATAAAGAGTTAAAGCTCTGTCCTCTAAATAGAAGCCTG GCCAAAGGGAGAAAACAGTGGGAGTCCCTTTTCCCTTTTAACAAGTTTGCAATAGACACTTCTTTTTTTCCTGTCTCAATGGATGTGTGC |
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FusionGenePPI for ELAVL1_ATXN10 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ELAVL1 | RPAP1, RUVBL1, TAF10, POLR2J, GIGYF2, SRRM2, H2AFX, TOP1, SREK1, SLC38A2, TRPC1, INTS3, CNOT8, UHMK1, LYN, ERP44, SLC27A6, STK24, SERINC3, TBL1XR1, CASD1, ZNF554, FOXN2, FCHSD2, MAP4K5, OCRL, DDAH1, AKAP8, IKBIP, EAPP, RNF149, TTC33, LAMTOR1, HERPUD2, CELF1, NCOA3, HES1, ADAT1, MARVELD2, CISD2, TCF7L2, IGIP, AMMECR1L, KLHL3, SMPD1, WDR45B, LTA4H, UBXN6, FAM105A, MED20, LIMK1, ATP1B1, GCLC, MSN, MRGBP, MPZL1, PEX19, CLDN12, TMEM2, TMEM263, INO80C, PHACTR2, EPHB4, TRERF1, SNX19, SRSF9, NADK2, MKNK2, SORT1, CDK9, ATM, HLTF, SNRNP48, MGEA5, ZHX1, TFAP2C, TSPAN31, PSMD5, PPP6C, XPO4, G3BP1, NEIL2, COL1A1, FXR1, PPP2R5E, PATL1, SESN3, MANBAL, OSBPL2, CBX3, USB1, PAPD5, PPTC7, FANCD2, IRX1, PCGF2, SNTB2, SENP2, TRIM37, DHX33, ODF2, ZFR, VSIG10, MTA2, CDV3, UHRF1, HMG20A, LPHN1, DR1, KIF20B, PKN2, KCTD9, FNDC3A, CPSF2, CAPZA2, RASL10B, HNRNPA0, SDC2, SAMD1, SPRED2, SPSB1, TMEM216, TUFT1, RERE, RFWD2, HSD17B11, PUM2, UBE2J1, ORMDL3, MDC1, MAPKAPK2, ZBTB46, IER2, METTL21B, DHRS3, UFM1, PITPNB, CMPK1, ITPKB, ZBTB33, RABL2A, E2F3, INSIG1, DUSP28, KIF1B, TCEAL8, FAM46A, TMEM9B, PRKAA1, KDM2A, ETV5, ARID1A, CREB3L2, NDUFC2, ZNF770, NUAK1, CLINT1, GLIPR2, CCP110, EBP, MARCH2, DICER1-AS1, TMEM38B, FKBP1A, CRIPT, NPLOC4, ACSL4, PDCD4, UBE2H, DUSP5, DUSP15, BARD1, SMAD2, ENAH, RYK, LAMTOR3, ZNF426, AKIRIN2, TMEM52B, TROAP, CARD8, OXSR1, TRIM38, GIGYF1, TMEM68, ZC3HAV1, RYBP, EFHD2, ZNF91, ASB6, BRD2, FAM172A, PPP3CB, BTBD3, SLC39A10, RBM15, CDCA8, TMTC4, UST, ARPC5, COL4A5, FAM219B, NUAK2, SKP2, OTULIN, PHTF2, TANGO2, FANCE, SPOCK1, DPP8, TTPAL, USP3, SRD5A1, GAL, STAU1, EIF4B, ZMPSTE24, SDCCAG3, ARL5A, TP53TG3, PRPS2, CALM1, GPR180, IRF9, TOB1, RNF219, SHOX2, SPRED1, EEF2K, MTRR, FAM110B, VPS26A, ZAK, CAPZA1, ICMT, AMFR, LRTOMT, SRSF8, NIPAL3, LPCAT4, CTLA4, TGFB3, HNRNPA1, CFAP45, CDC42SE1, HOXC11, SNRPF, VPS36, GOLGA3, PHLDA1, PDCL, CDC42, EIF2S3, GRPEL2, XKR6, TRIOBP, LAMC1, TMX1, METTL7A, CNOT7, C2orf68, CD8B, CDH9, SLC35F6, ZCCHC14, SKA1, CDC42SE2, CD79B, DTD2, PHYH, SCML1, ZNF528, SLC25A37, PFDN2, KIAA0430, SNX6, SLC25A15, DDX3X, CYB5B, CCND1, SEH1L, DUSP7, TMEM19, FAM83H, GLYR1, IMPA1, ZC2HC1A, MSRB2, CAMKMT, TTL, PFKFB3, PTP4A3, TMEM189, ANKRD13A, PDE4DIP, MEAF6, G3BP2, DNAJB11, MED1, SLC19A2, VAV2, IDH1, PIGN, PITHD1, ARMC1, FAM49B, NUSAP1, RRP1B, TFPI, DNAJB9, AGPAT9, VTA1, SGOL1, EPB41L3, GSR, TBCCD1, IRS2, SLC35F2, SLC16A6, DUSP3, CTBS, TMED7, MTA3, MED28, CEPT1, TC2N, CDCA7L, CASK, RBBP4, CLASP1, RPN1, GMFB, ZEB2, AAGAB, DTX3L, CAMSAP2, PSMG3, ANXA7, SLC25A43, PPM1F, KDM5B, ARPC1A, TYW1, NFIB, ACBD3, TES, CASC4, ELK1, ANTXR1, TSPAN14, ZNF668, FBXO27, COLGALT1, YES1, LPCAT1, RAB21, SLMO2, RBM17, HNRNPDL, EXOSC6, YTHDF1, FOXO3, SMARCC1, GALNT4, ISOC1, ELF2, JPH1, MYNN, APIP, RCOR3, GDI2, DDX39B, PI4K2B, MARCKS, SPAST, LATS2, CBR4, ZBTB2, ALYREF, FARP1, ZMYM2, SMIM12, SATB2, YWHAG, COPS7B, CSNK1E, MSANTD3, NXT2, CEP164, CPS1, SAV1, COL15A1, IL13RA1, ADRA1D, SLC2A3, JARID2, ZFHX3, RDH10, RBPJ, EXOC8, GNL3L, MLLT6, CHRM2, PLEKHA1, FNBP1, STARD3NL, HOXA5, C9orf64, TP53INP1, BLCAP, ATP2C1, TCF12, CAST, PAXIP1, CYP51A1, SAYSD1, SFXN1, TUBB3, DLG4, DAG1, EIF4EBP2, RNF122, UBA6, RAP2A, AAED1, XPO1, ZYG11B, MT1X, TMEM180, SMAD6, MPV17L, ADAMTS4, SUMO2, TAF2, WAPAL, HIRA, HP, DDX46, RBM14, DENND1C, C16orf87, GDPGP1, TSPAN13, EWSR1, NUCKS1, WSB2, ANKRD10, F3, FGFR1OP2, DCK, SH3PXD2A, WDR44, CRYL1, TUBGCP3, ZNF395, AMMECR1, MARCKSL1, CLUAP1, TPM3, ITCH, DESI2, RAP2C, AXL, FOPNL, SCAMP4, PTPN11, PCGF6, LIPA, OLR1, PRKCI, MTFMT, ANXA2R, SERBP1, SOX4, ARID5B, SAR1A, KLF5, SPATA2, STT3A, TJP1, TFAP4, GFOD1, RHOF, DCTD, TM9SF3, NCCRP1, RNASEH1, PPP4C, CCNT2, OSBPL3, RBBP5, RASL11A, PLAC8, PIAS4, SNX27, ZBTB43, RIN2, PLEKHA5, USP28, PPP1R2, CSNK1G3, VPS72, CNOT6, CHSY1, PRKAR2A, HCCS, EVI5, GATAD2A, DYRK1A, CENPH, DNAJC15, STRN, BCDIN3D, ZBED3, CPNE3, ZNF200, KDELR2, MAK16, ERMP1, ZNF532, FKBP14, SLC35G1, FNDC3B, MRPS27, CNNM3, MMGT1, VEZF1, C4orf32, ST13, BLOC1S6, ARNT, C2CD5, SALL4, PABPC4, DAZAP1, TUSC1, FBXO11, IFIT5, SCAF4, MESDC1, KATNAL1, FLYWCH1, AIF1L, LRRC8A, RRM2, HEY1, TFDP1, CCNY, LRRC47, SLC30A9, RBM25, MYBPH, RPS6KB1, EPT1, ARID3A, STX12, SH3KBP1, RBFOX2, GNAZ, MB21D1, FAM199X, HMGN2P46, TAPBP, TFAP2A, SSX2IP, APPL1, TOR1AIP1, CALR, NEDD4L, LLGL1, TXLNA, MAT2B, PRKAR1A, GTF2E1, ZNF281, NAB1, MECP2, MRPS16, STAT2, SLC50A1, ZNF280B, PPIC, YOD1, PIGM, RUNX1, RAN, TTI2, GLE1, CCDC6, TMCO3, LSM14A, GART, YAP1, ALKBH5, RPRD2, SPRY2, RAD23B, FAM72D, AMER1, TMEM159, SSH1, GLCE, SRPK1, DIABLO, SERPINE2, SUPT16H, RBX1, CDK2AP1, HDAC4, RIOK3, C5orf22, MAP2K1, PREPL, FAM114A2, E2F2, KAT6A, KLHL8, TBC1D20, TBC1D22B, LIN7C, RC3H2, SCAMP1, TMEM14A, APLP2, ATP2A2, NUFIP2, RAP1A, OSBP, CD70, ISCA1, TLK1, GATA2, BAZ2B, RRNAD1, LOC93622, TMEM189-UBE2V1, CPNE8, RDH5, ARHGEF11, HCN3, TOMM22, AMD1, GNB5, MYO5C, FEM1C, C2CD2, MKLN1, NABP1, TIMM13, CREBZF, GLOD4, TOB2, BIRC5, AVP, ZNF148, FGD1, RSL24D1, REEP1, SLC30A7, TOMM20, C12orf49, RSU1, IFT74, ADAR, GPD1L, TMEM65, PAN3, HELZ, SLC9A5, FOXP1, TULP2, RAB2B, CA5B, LGALSL, EIF2AK2, NT5DC3, DDR2, ZNF217, TGFBR1, B4GALT1, YIPF2, FAM83F, CNEP1R1, ANGEL2, TP53RK, STAU2, UBASH3B, C4orf46, RSBN1, PAPOLA, ZNHIT6, MOB3A, CBX6, PTK2, REXO1, ARPP19, CANX, PRR3, VHL, DIO2, LARP4B, KPNA6, SMS, VPS35, KPNA4, TERF2, UPF2, KLF11, NAP1L4, ARHGEF2, CENPL, C9orf91, RCC2, EIF4E3, MNT, ZNF696, LARP4, OSGIN2, STOML2, PCDH9, UBE2Q2, EPB41L1, ZCCHC7, STK4, OSTM1, SLC22A5, MBD3, PAPPA, ACTR2, VPS4B, AHCYL1, TRAK2, USF1, CITED2, JOSD1, SDAD1, PROSER3, LINC00272, CHRAC1, VMA21, CREBL2, MIR600HG, CCDC117, OR14I1, EML4, IER3IP1, SETD8, OSBPL11, PAPD4, NAA25, ATP7B, CTBP1, PIM1, RAB10, SNX10, CHTOP, TTYH3, ARHGAP19, GNAI3, OSR2, MAPK6, PARVA, CAMK2N1, C3orf33, EIF1AX, BRD4, CCNI, DDX18, GUCD1, SLC39A11, PRSS23, PTRF, CTNNBIP1, GOLPH3, FAM107B, C6orf106, BMI1, OTUD6B, NLGN2, FAM120AOS, FAM76B, MOB3B, ACVR1B, IGF2BP2, NFIC, ZNF521, NXN, CAAP1, TRIM8, SLC7A1, TGFBR3, TBX3, SSB, PPIA, CD47, INPP4B, RHOQ, RNF38, CRLF3, ACTN4, SPTSSA, RALA, AQP3, CD164, ELMSAN1, C11orf57, LACTB, VEZT, LRRFIP2, RNF41, TOLLIP, TMEM56, TMEM123, C3orf52, ZNF573, METTL2A, MIER1, RPIA, CHP1, ING3, C5orf15, ATP6V0A2, GEMIN6, ANKRD40, HECTD2, C12orf75, SSR1, SUPV3L1, DENR, NKTR, TUBB, NDFIP2, AHI1, IRF2BPL, IQSEC2, SIK1, NCS1, SLC44A1, PFN1, SPRY1, ZNF562, TULP4, FOXC1, MTR, ZFAND1, PHACTR4, MAL2, PAK2, ERH, SPIN1, ROCK2, COPG2, TAF11, MTHFD2, MGRN1, POGK, PNPO, RRN3, NSUN4, POTEKP, MUM1, ATG14, STX7, CXADR, GPM6B, CSK, MTMR2, KMT2C, DENND5A, CHPT1, FAM175B, PRKCA, BHLHE40, ARPC4, CCL7, TMEM101, AP1AR, SYT15, WTAP, ATG16L1, CLN3, HCFC1, POLR2D, ZDHHC3, RSPRY1, RPP14, CIRBP, TBL1X, STRADB, CHIC2, HNRNPC, PUM1, MLEC, NREP, GPR3, AGMAT, SDC4, FAM13B, SGK1, ZNF529, SRPRB, FAM178A, PDXK, ZNF800, APH1A, GALNT1, TWISTNB, SEMA4D, CIPC, MICB, DEK, PABPC1, SEPT7, SAFB, RAVER1, PNRC1, LMNB2, CFP, MTF2, PVR, ASCC1, C8orf4, SRRM1, PPP2R2A, TRIM2, PRR14, PRRC1, PCBP2, ING1, GLTSCR1L, FUBP1, DIP2B, ASB3, SRSF6, CSNK1A1, BAZ1A, RNF141, UBL3, SLC48A1, RNF212, HMOX1, RNPS1, AES, RBL2, FAM208A, FOXA1, ALDH1A3, SNRNP40, TGIF2, TMEM127, LAPTM4A, IFNGR2, UBP1, AUNIP, NUDT3, THOC6, HEATR5B, KRCC1, PTPLB, B3GALTL, AGO2, FAM102B, FAM131A, SCD, FOXL2, SLC7A5, RAB6A, IQGAP3, FZD6, MLLT10, HSPA1B, TMEM209, ZNF561, DEPDC1, PHC1, GCA, MAT2A, PMAIP1, ACTB, RANBP1, MED21, SIPA1L3, EIF1AD, ZNF543, SIK3, GNA11, CTH, GAPVD1, SNX3, KIF21A, ZNF664, SLC25A44, PTEN, PER2, ZNF746, MED4, HEATR3, MAP3K12, KRAS, CREBBP, CEP57L1, MBD6, SPIN3, FOXJ3, GNB1, EIF5A, MECOM, CNOT4, WDFY1, LIN54, LCLAT1, TOR1A, CDR2L, TRAM2, CDKAL1, MARCH6, C1orf198, PPP3R1, ZNF638, EPAS1, IGF2BP3, UBXN4, SMIM7, KCNK1, CASC10, TLK2, NLK, RPRM, KLF9, LAMP2, LRRC1, PLEKHF2, AP4E1, MORF4L1, RNF150, LMAN1, LDLRAD3, VMP1, KLHL24, FOXN3, SKP1, SLC43A2, ARSB, LZTFL1, CEBPA, LEPROT, STK26, SUB1, RNF115, STK35, TMEM167B, CCDC58, CEP57, CHD1, FKBP9, SEPT11, YWHAH, PRIM2, GID8, MEX3D, IL1B, RAB22A, PTP4A1, GIT1, CHMP1B, RAB5A, ZBTB20, SMIM11, LONP2, MTAP, PHF1, RANBP3, MTMR4, SETD3, PBX1, PRUNE, API5, SMNDC1, MSMO1, DNAJC14, FOXJ2, PARP12, NFIA, TMEM97, LAMP1, PEX26, DOLPP1, EIF2S1, ZBTB14, PDZD8, PHF21A, DDX17, TMOD3, UBE4B, PLD6, PTBP3, MTPN, MYC, OAZ2, RHOB, ARHGEF35, R3HDM2, TMEM63B, TMEM30A, KDM3B, SERPINH1, SLC41A1, NIP7, MOSPD2, C18orf54, DYNC1LI2, FAF2, DUSP19, MKX, FEM1A, CIT, MED23, NR4A2, C5orf30, CASC3, CTIF, BBX, HIBADH, MRPS10, KIAA0895, FAM60A, PIAS3, CPOX, SEPHS1, SLC9A6, ZCCHC3, RDX, S100PBP, CYP26B1, PHLPP1, TRMT13, ARL2BP, SETD9, SRBD1, STC2, PRKDC, PUS7, HDAC2, CCDC92, PDSS2, C1orf86, STRN3, ZIC2, ATG5, KATNBL1, C1QL1, AEBP2, NRIP3, BASP1, NR5A1, LSM11, PDCD6IP, H2AFV, FAM117B, CASP3, DDA1, TAF4, YTHDF2, SEC22B, ADAMTSL5, UBE2E2, TRIB1, TMEM207, ZNF234, DCAF12, GLUD1, GBE1, RQCD1, DVL2, JUND, PURB, VGLL4, DMKN, ZNF77, TIMM22, EZR, TGIF1, NUP93, SEC14L4, SMG7, TCTN2, PCSK7, ALPI, FAM192A, RBM47, TMEM134, OR6T1, GTF3C1, TTC5, PABPN1, STAT3, GOLPH3L, SUSD6, BCL9, IGF2R, F11R, GNE, MCU, NHLH1, CXCL16, RABL2B, SHQ1, PRMT6, FRS3, FAM217B, RICTOR, TSPYL1, MTMR6, COQ10B, NUTF2, RBM4B, PDCL3, TGFA, RAB7A, ADAM23, LDHAL6A, NSUN6, HECA, BCAP29, TSPAN9, EXPH5, DRAM2, BAG4, CDC23, NAV1, OSTF1, POLR2A, KIAA1715, SPPL3, ATP6V1A, PRRC2C, SCP2, GLTP, TUBA3D, TMED4, ZNF714, KHSRP, CSDE1, PARP1, CDK6, NIN, GAS1, PDCD7, LIMCH1, JADE3, BTF3L4, RFWD3, TBCB, SFXN3, HMGB2, GMCL1, LPP, TBP, CBFB, ACACB, CTGF, FBXO30, FRMD8, MCM4, COTL1, DPY19L4, NRAS, TM9SF4, LUC7L2, ZBTB3, CALM3, ELOVL5, KAZN, NETO2, HAUS6, EPHA2, TRAM1, KCNAB1, WIPF1, RBMX2, MID1, PAQR7, STX11, TBPL1, TRIM33, TAF12, DUSP11, AP1S2, RAB5B, ACER3, C1orf174, RAPH1, UGDH, CCNJ, LRRC37B, SET, YY1, UBE2G1, PANK1, CD27, LMNB1, ARL6IP1, SPIN4, QKI, ARF5, EFR3A, HNRNPUL1, SLC10A3, MMD, CSNK2A1, PTDSS1, C16orf72, MEX3C, PIGA, ERRFI1, NRIP1, SERTAD2, MITF, ZDHHC14, GNA13, FAM73A, UBE2N, CTTN, CCDC28A, CKAP4, HIATL1, TEAD2, DNAJA2, PANK3, KIAA2013, PPP1R3C, DCBLD2, CCNK, NR3C1, LEPROTL1, ZFP91-CNTF, PDIA4, ABCB10, GOLIM4, CEBPB, ITGB1, ATAD1, WASL, TNPO2, GRB2, HNRNPH1, PPIL3, UBAP2L, BCL10, UBE2W, AZIN1, ZXDB, TMED2, CRKL, CEBPG, SETD2, THBS1, EML2, DAZAP2, ZCCHC11, ADIPOR1, CD9, RHNO1, DCP2, GSPT1, NPTX1, SGPL1, CTDSPL, GOLT1B, ZBTB18, SH2B3, PPP1CC, CCDC25, SKIDA1, SAMD4B, POLR3F, AGPAT1, USP33, NAP1L1, DOK4, FAM104B, TXNL4B, FECH, LYPLA1, CDCA4, BIN1, SNRPD3, AFMID, CPD, ARF4, PTBP2, BUB3, CARM1, TCF3, TRAPPC2, SRSF1, CDC37L1, EFCAB14, GAS2L3, NUP62CL, ZADH2, MTURN, IRF2BP2, TJAP1, GEMIN2, KDSR, PMP22, CHEK2, SFPQ, HK2, ETS1, SMARCC2, ORAOV1, MIS18BP1, PM20D2, B4GALT5, GFPT1, NEURL1, SZRD1, MBNL2, RNF138, ANP32B, NONO, ARL8B, SLC25A23, HNRNPL, NFYC, TFAM, ZNF747, PPP1R12A, LARP1, OSBP2, FAM193B, AKIRIN1, GPBP1L1, CTDSPL2, ZMYND11, CDKN1B, SMIM14, ASAP1, LRRC75A-AS1, ZNF623, SLC18B1, LINS, TRIM45, MXRA7, UBE2D3, PPFIBP1, ZSWIM1, ICE2, PRPF3, UBE2C, GK5, MIDN, ZNF76, CSRNP1, RNF182, RAB31, UBQLN2, XXYLT1, DCUN1D3, ARF3, PSMD9, PPP6R3, SS18, XIAP, C6orf62, RAB11A, NCL, TMX3, WDR33, PRKAG2, FURIN, RWDD4, TNFRSF1A, AK3, SNAP23, ARGLU1, OPA1, TM4SF1, SNX16, PPHLN1, TAF5L, ACIN1, ADNP2, GRB10, NAPB, UAP1, INHBE, SLC20A1, DZANK1, PTMA, RABGAP1, FAM84B, RAB1A, CDC42EP4, TNPO3, BRD3, SLC39A14, NR2F1, C9orf72, SLC38A6, ETV6, ZBTB41, CGGBP1, XPR1, FBXO4, UBE4A, GSK3B, WDR55, PBX2, STX2, BDNF, TMSB4XP8, ZFP91, SEPN1, PJA2, TMEM194A, FBXO21, PCNP, SELT, XK, JDP2, PPP1CB, CNOT11, FAM46C, PCMTD1, AP3S1, ZNF264, ANAPC16, CD44, ZNF362, SRGAP1, ERLIN2, LPGAT1, MTA1, TM7SF3, CHST3, UBE2F, TMEM241, PPP2R1A, SPRR1A, EIF1B, CMTM6, LITAF, ELK4, PCBP1, SLC16A4, ZNF764, ZMYND19, EAF1, SUZ12, P4HA1, TPM1, TOX4, RIOK1, FAM134C, FAM160B1, TMCO1, TRA2A, HCST, SIRT1, ZBTB39, BRPF3, TMEM41B, CHD4, TMEM59, C5orf51, ASAP2, SMAD5, MAP2K7, PLCXD1, SSH2, RBM33, MYADM, RPRD1A, SLC30A5, PRDM1, SENP1, ABHD10, COX7A2L, NDRG3, DLG3, CPM, KIF11, ANO6, SDE2, MGST3, YIPF6, CCDC14, NET1, CASP2, BTAF1, ABCG1, BZW2, PIP4K2C, PAPD7, SLC35E2, HIAT1, NCSTN, HNRNPF, U2AF1L4, DSC2, PXDC1, EPS15, NEO1, YPEL5, UBE2L3, GM2A, APAF1, RAB8A, SLC25A32, EPB41L4B, ZMAT3, ANKRD46, YBX3, TXNIP, APOBEC3C, KMT2E, TM2D1, SMG1, SH3D19, DCAKD, BIVM, BCL2L2, CORO1C, MTPAP, PRRG1, THAP10, GSE1, NAPG, UBE3C, RNF144B, SLC16A5, CNN2, VKORC1L1, DCUN1D4, EDEM1, IFI6, HIF1AN, MTMR9, HRK, ZFP36L1, FAM20B, FAM76A, SH2D1A, SGPP1, SSTR2, FLYWCH2, FBXO8, YWHAB, ZNRF2, TXNRD1, ZDHHC17, TNFRSF21, KPNB1, AKIP1, DPYSL2, TRIM65, AGPAT5, PDE7B, SUMF2, ZCRB1, CDK12, GRAMD3, GABARAPL2, C18orf25, AK4, TSC22D3, IQCB1, ZNF556, SERTAD4, MTCP1, LARP1B, FGF21, KLF2, TIFA, SF3A2, SIRT7, ISG15, CUL3, CUL4B, CUL5, CUL2, CUL1, COPS5, CAND1, VEGFA, TP53, PTHLH, TNF, NOS3, APOE, PSEN2, SLC25A5, SRSF5, RPS28, VDAC2, NDUFA9, SLIRP, RPS15, RMDN3, S100A10, KRT10, OCIAD1, SRSF3, ABCD1, BTRC, CHUK, FN1, VCAM1, ELAVL1, HNRNPK, PTBP1, PRKCD, PRKCE, IL7R, PLAU, PLAUR, VCP, PAN2, GJB3, CTNNB1, PTGS2, CELF2, TARDBP, HECW2, PARK2, MIRLET7B, MIRLET7I, HOTAIR, RPA3, RPA2, RPA1, WWOX, ERG, IVNS1ABP, MIR29A, TNFAIP3, SOCS3, HDAC6, TRAF3IP2, TRAF2, TRAF5, SDCBP, CUL7, OBSL1, CCDC8, EZH2, EED, RNF2, FBXW11, MAEL, DUT, SLC25A13, GNB2L1, HNRNPA2B1, STIP1, NTRK1, ANP32A, IGF2BP1, MKRN1, SNW1, CDC5L, U2AF2, MIR16-1, RBM3, CYLD, COX15, DLD, HSD17B10, PDHA1, SDHA, SOD1, VDAC1, TRIM25, UBE2A, LMNA | ATXN10 | BSG, STYXL1, MAGED1, GSTK1, CUL3, PPP1R12A, GNB1, GNB2, FN1, MRPS16, GLS, GOLGA1, ABCA1, CA9, VCP, EGFR, SERPINH1, HSPA1A, HSPA8, CCDC8, ABCE1, HTR6, HSPB1, CEP162, CEP152, CEP128, SCLT1, CENPJ, LAMB3, MYC, UBE2A, TUBA1C, MTMR14, DUSP22, PTPRN, STOM, DLD |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ELAVL1_ATXN10 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ELAVL1_ATXN10 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ELAVL1 | C0014175 | Endometriosis | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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