|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 11250 |
FusionGeneSummary for EIF3B_GDI2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: EIF3B_GDI2 | Fusion gene ID: 11250 | Hgene | Tgene | Gene symbol | EIF3B | GDI2 | Gene ID | 8662 | 2665 |
| Gene name | eukaryotic translation initiation factor 3 subunit B | GDP dissociation inhibitor 2 | |
| Synonyms | EIF3-ETA|EIF3-P110|EIF3-P116|EIF3S9|PRT1 | HEL-S-46e|RABGDIB | |
| Cytomap | 7p22.3 | 10p15.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | eukaryotic translation initiation factor 3 subunit Beukaryotic translation initiation factor 3 subunit 9eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD)eukaryotic translation initiation factor 3, subunit 9 eta, 116kDaprt1 homolog | rab GDP dissociation inhibitor betaGDI-2epididymis secretory sperm binding protein Li 46eguanosine diphosphate dissociation inhibitor 2rab GDI betarab GDP-dissociation inhibitor, beta | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | P55884 | P50395 | |
| Ensembl transtripts involved in fusion gene | ENST00000360876, ENST00000397011, | ENST00000380191, ENST00000479928, ENST00000380132, ENST00000380181, | |
| Fusion gene scores | * DoF score | 8 X 11 X 4=352 | 8 X 6 X 4=192 |
| # samples | 11 | 8 | |
| ** MAII score | log2(11/352*10)=-1.67807190511264 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/192*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: EIF3B [Title/Abstract] AND GDI2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | EIF3B | GO:0006413 | translational initiation | 8995410|17581632 |
| Hgene | EIF3B | GO:0006446 | regulation of translational initiation | 8995410 |
| Hgene | EIF3B | GO:0075522 | IRES-dependent viral translational initiation | 9573242 |
| Hgene | EIF3B | GO:0075525 | viral translational termination-reinitiation | 21347434 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-SG-A849-01A | EIF3B | chr7 | 2418877 | + | GDI2 | chr10 | 5828013 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000360876 | ENST00000380191 | EIF3B | chr7 | 2418877 | + | GDI2 | chr10 | 5828013 | - |
| 5CDS-intron | ENST00000360876 | ENST00000479928 | EIF3B | chr7 | 2418877 | + | GDI2 | chr10 | 5828013 | - |
| 5CDS-intron | ENST00000360876 | ENST00000380132 | EIF3B | chr7 | 2418877 | + | GDI2 | chr10 | 5828013 | - |
| 5CDS-intron | ENST00000360876 | ENST00000380181 | EIF3B | chr7 | 2418877 | + | GDI2 | chr10 | 5828013 | - |
| In-frame | ENST00000397011 | ENST00000380191 | EIF3B | chr7 | 2418877 | + | GDI2 | chr10 | 5828013 | - |
| 5CDS-intron | ENST00000397011 | ENST00000479928 | EIF3B | chr7 | 2418877 | + | GDI2 | chr10 | 5828013 | - |
| 5CDS-intron | ENST00000397011 | ENST00000380132 | EIF3B | chr7 | 2418877 | + | GDI2 | chr10 | 5828013 | - |
| 5CDS-intron | ENST00000397011 | ENST00000380181 | EIF3B | chr7 | 2418877 | + | GDI2 | chr10 | 5828013 | - |
Top |
FusionProtFeatures for EIF3B_GDI2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| EIF3B | GDI2 |
| RNA-binding component of the eukaryotic translationinitiation factor 3 (eIF-3) complex, which is required for severalsteps in the initiation of protein synthesis (PubMed:9388245,PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3complex associates with the 40S ribosome and facilitates therecruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5to form the 43S pre-initiation complex (43S PIC). The eIF-3complex stimulates mRNA recruitment to the 43S PIC and scanning ofthe mRNA for AUG recognition. The eIF-3 complex is also requiredfor disassembly and recycling of post-termination ribosomalcomplexes and subsequently prevents premature joining of the 40Sand 60S ribosomal subunits prior to initiation (PubMed:9388245,PubMed:17581632). The eIF-3 complex specifically targets andinitiates translation of a subset of mRNAs involved in cellproliferation, including cell cycling, differentiation andapoptosis, and uses different modes of RNA stem-loop binding toexert either translational activation or repression(PubMed:25849773). {ECO:0000255|HAMAP-Rule:MF_03001,ECO:0000269|PubMed:17581632, ECO:0000269|PubMed:25849773,ECO:0000269|PubMed:27462815, ECO:0000269|PubMed:9388245}. (Microbial infection) In case of FCV infection, plays arole in the ribosomal termination-reinitiation event leading tothe translation of VP2 (PubMed:18056426).{ECO:0000269|PubMed:18056426}. | Regulates the GDP/GTP exchange reaction of most Rabproteins by inhibiting the dissociation of GDP from them, and thesubsequent binding of GTP to them. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000360876 | + | 17 | 19 | 185_268 | 780 | 810 | Domain | RRM |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000397011 | + | 17 | 19 | 185_268 | 780 | 791 | Domain | RRM |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000360876 | + | 17 | 19 | 285_324 | 780 | 810 | Repeat | Note=WD 1 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000360876 | + | 17 | 19 | 325_365 | 780 | 810 | Repeat | Note=WD 2 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000360876 | + | 17 | 19 | 366_425 | 780 | 810 | Repeat | Note=WD 3 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000360876 | + | 17 | 19 | 426_489 | 780 | 810 | Repeat | Note=WD 4 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000360876 | + | 17 | 19 | 490_553 | 780 | 810 | Repeat | Note=WD 5 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000360876 | + | 17 | 19 | 554_598 | 780 | 810 | Repeat | Note=WD 6 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000360876 | + | 17 | 19 | 599_642 | 780 | 810 | Repeat | Note=WD 7 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000360876 | + | 17 | 19 | 643_685 | 780 | 810 | Repeat | Note=WD 8 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000397011 | + | 17 | 19 | 285_324 | 780 | 791 | Repeat | Note=WD 1 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000397011 | + | 17 | 19 | 325_365 | 780 | 791 | Repeat | Note=WD 2 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000397011 | + | 17 | 19 | 366_425 | 780 | 791 | Repeat | Note=WD 3 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000397011 | + | 17 | 19 | 426_489 | 780 | 791 | Repeat | Note=WD 4 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000397011 | + | 17 | 19 | 490_553 | 780 | 791 | Repeat | Note=WD 5 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000397011 | + | 17 | 19 | 554_598 | 780 | 791 | Repeat | Note=WD 6 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000397011 | + | 17 | 19 | 599_642 | 780 | 791 | Repeat | Note=WD 7 |
| Hgene | EIF3B | chr7:2418877 | chr10:5828013 | ENST00000397011 | + | 17 | 19 | 643_685 | 780 | 791 | Repeat | Note=WD 8 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for EIF3B_GDI2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_EIF3B_ENST00000360876_chr7_2418877_+_GDI2_ENST00000380191_chr10_5828013_-_1097aa MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAE ELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFD KYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYE TPSMGLLDKKSLKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRS MNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGLMGLFEKRRFRKFLVYVANFDEKDPRTFE GIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTY MLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISF AHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKNIYKRMTGSEF >In-frame_EIF3B_ENST00000397011_chr7_2418877_+_GDI2_ENST00000380191_chr10_5828013_-_1097aa MQDAENVAVPEAAEERAEPGQQQPAAEPPPAEGLLRPAGPGAPEAAGTEASSEEVGIAEAGPESEVRTEPAAEAEAASGPSESPSPPAAE ELPGSHAEPPVPAQGEAPGEQARDERSDSRAQAVSEDAGGNEGRAAEAEPRALENGDADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEA DGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKITNDFYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFD KYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALW GGEKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYE TPSMGLLDKKSLKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGV VTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKNNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRS MNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQEQIKQI KKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRKYRKMAQELYMEQKNERLELRGGLMGLFEKRRFRKFLVYVANFDEKDPRTFE GIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTY MLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISF AHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKNIYKRMTGSEF |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_EIF3B_ENST00000360876_chr7_2418877_+_GDI2_ENST00000380191_chr10_5828013_-_3291nt ATGCAGGACGCGGAGAACGTGGCGGTGCCCGAGGCGGCCGAGGAGCGCGCCGAGCCCGGCCAGCAGCAGCCGGCCGCCGAGCCGCCGCCA GCCGAGGGGCTGCTGCGGCCCGCGGGGCCCGGCGCTCCGGAGGCCGCGGGGACCGAGGCCTCCAGTGAGGAGGTGGGGATCGCGGAGGCC GGGCCGGAGTCCGAGGTGAGGACCGAGCCGGCGGCCGAGGCAGAGGCGGCCTCCGGCCCGTCCGAGTCGCCCTCGCCGCCGGCCGCCGAG GAGCTGCCCGGGTCGCATGCTGAGCCCCCTGTCCCGGCACAGGGCGAGGCCCCAGGAGAGCAGGCTCGGGACGAGCGCTCCGACAGCCGG GCCCAGGCGGTGTCCGAGGACGCGGGAGGAAACGAGGGCAGAGCGGCCGAGGCCGAACCCCGGGCGCTGGAGAACGGCGACGCGGACGAG CCCTCCTTCAGCGACCCCGAGGACTTCGTGGACGACGTGAGCGAGGAAGAATTACTGGGAGATGTACTCAAAGATCGGCCCCAGGAAGCA GATGGAATCGATTCGGTGATTGTAGTGGACAATGTCCCTCAGGTGGGACCCGACCGACTTGAGAAACTCAAAAATGTCATCCACAAGATC TTTTCCAAGTTTGGGAAAATCACAAATGATTTTTATCCTGAAGAGGATGGGAAGACAAAAGGGTATATTTTCCTGGAGTACGCGTCCCCT GCCCACGCTGTGGATGCTGTGAAGAACGCCGACGGCTACAAGCTTGACAAGCAGCACACATTCCGGGTCAACCTCTTTACGGATTTTGAC AAGTATATGACGATCAGTGACGAGTGGGATATTCCAGAGAAACAGCCTTTCAAAGACCTGGGGAACTTACGTTACTGGCTTGAAGAGGCA GAATGCAGAGATCAGTACAGTGTGATTTTTGAGAGTGGAGACCGCACTTCCATATTCTGGAATGACGTAAAAGACCCTGTCTCAATTGAA GAAAGAGCGAGATGGACAGAGACGTATGTGCGTTGGTCTCCTAAGGGCACCTACCTGGCTACCTTTCATCAAAGAGGCATTGCTCTATGG GGGGGAGAGAAATTCAAGCAAATTCAGAGATTCAGCCACCAAGGGGTTCAGCTTATTGACTTCTCACCTTGTGAAAGGTACCTGGTGACC TTTAGCCCCCTGATGGACACGCAGGATGACCCTCAGGCCATAATCATCTGGGACATCCTTACGGGGCACAAGAAGAGGGGTTTTCACTGT GAGAGCTCAGCCCATTGGCCTATTTTTAAGTGGAGCCATGATGGCAAATTCTTTGCCAGAATGACCCTGGATACGCTTAGCATCTATGAA ACTCCTTCTATGGGTCTTTTGGACAAGAAGAGTTTGAAGATCTCTGGGATAAAAGACTTTTCTTGGTCTCCTGGTGGTAACATAATCGCC TTCTGGGTGCCTGAAGACAAAGATATTCCAGCCAGGGTAACCCTGATGCAGCTCCCTACCAGGCAAGAGATCCGAGTGAGGAACCTGTTC AATGTGGTGGACTGCAAGCTCCATTGGCAGAAGAACGGAGACTACTTGTGTGTGAAAGTAGATAGGACTCCGAAAGGCACCCAGGGTGTT GTCACAAATTTTGAAATTTTCCGAATGAGGGAGAAACAGGTACCTGTGGATGTGGTCGAGATGAAAGAAACCATCATAGCCTTTGCCTGG GAACCAAATGGAAGTAAGTTTGCTGTGCTGCACGGAGAGGCTCCGCGGATATCTGTGTCTTTCTACCACGTCAAAAACAACGGGAAGATT GAACTCATCAAGATGTTCGACAAGCAGCAGGCGAACACCATCTTCTGGAGCCCCCAAGGACAGTTCGTGGTGTTGGCGGGCCTGAGGAGT ATGAACGGTGCCTTAGCGTTTGTGGACACTTCGGACTGCACGGTCATGAACATCGCAGAGCACTACATGGCTTCCGACGTCGAATGGGAT CCTACTGGGCGCTACGTCGTCACCTCTGTGTCCTGGTGGAGCCATAAGGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGCCTC CTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAAATT AAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGAAGG CGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGAGGA GGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAA GGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTT GCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATAT GGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTAT ATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAG CTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCCAGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAG AACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAGTCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTT GCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAACTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCT TTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACCTCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTT ATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATGACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTT >In-frame_EIF3B_ENST00000397011_chr7_2418877_+_GDI2_ENST00000380191_chr10_5828013_-_3291nt ATGCAGGACGCGGAGAACGTGGCGGTGCCCGAGGCGGCCGAGGAGCGCGCCGAGCCCGGCCAGCAGCAGCCGGCCGCCGAGCCGCCGCCA GCCGAGGGGCTGCTGCGGCCCGCGGGGCCCGGCGCTCCGGAGGCCGCGGGGACCGAGGCCTCCAGTGAGGAGGTGGGGATCGCGGAGGCC GGGCCGGAGTCCGAGGTGAGGACCGAGCCGGCGGCCGAGGCAGAGGCGGCCTCCGGCCCGTCCGAGTCGCCCTCGCCGCCGGCCGCCGAG GAGCTGCCCGGGTCGCATGCTGAGCCCCCTGTCCCGGCACAGGGCGAGGCCCCAGGAGAGCAGGCTCGGGACGAGCGCTCCGACAGCCGG GCCCAGGCGGTGTCCGAGGACGCGGGAGGAAACGAGGGCAGAGCGGCCGAGGCCGAACCCCGGGCGCTGGAGAACGGCGACGCGGACGAG CCCTCCTTCAGCGACCCCGAGGACTTCGTGGACGACGTGAGCGAGGAAGAATTACTGGGAGATGTACTCAAAGATCGGCCCCAGGAAGCA GATGGAATCGATTCGGTGATTGTAGTGGACAATGTCCCTCAGGTGGGACCCGACCGACTTGAGAAACTCAAAAATGTCATCCACAAGATC TTTTCCAAGTTTGGGAAAATCACAAATGATTTTTATCCTGAAGAGGATGGGAAGACAAAAGGGTATATTTTCCTGGAGTACGCGTCCCCT GCCCACGCTGTGGATGCTGTGAAGAACGCCGACGGCTACAAGCTTGACAAGCAGCACACATTCCGGGTCAACCTCTTTACGGATTTTGAC AAGTATATGACGATCAGTGACGAGTGGGATATTCCAGAGAAACAGCCTTTCAAAGACCTGGGGAACTTACGTTACTGGCTTGAAGAGGCA GAATGCAGAGATCAGTACAGTGTGATTTTTGAGAGTGGAGACCGCACTTCCATATTCTGGAATGACGTAAAAGACCCTGTCTCAATTGAA GAAAGAGCGAGATGGACAGAGACGTATGTGCGTTGGTCTCCTAAGGGCACCTACCTGGCTACCTTTCATCAAAGAGGCATTGCTCTATGG GGGGGAGAGAAATTCAAGCAAATTCAGAGATTCAGCCACCAAGGGGTTCAGCTTATTGACTTCTCACCTTGTGAAAGGTACCTGGTGACC TTTAGCCCCCTGATGGACACGCAGGATGACCCTCAGGCCATAATCATCTGGGACATCCTTACGGGGCACAAGAAGAGGGGTTTTCACTGT GAGAGCTCAGCCCATTGGCCTATTTTTAAGTGGAGCCATGATGGCAAATTCTTTGCCAGAATGACCCTGGATACGCTTAGCATCTATGAA ACTCCTTCTATGGGTCTTTTGGACAAGAAGAGTTTGAAGATCTCTGGGATAAAAGACTTTTCTTGGTCTCCTGGTGGTAACATAATCGCC TTCTGGGTGCCTGAAGACAAAGATATTCCAGCCAGGGTAACCCTGATGCAGCTCCCTACCAGGCAAGAGATCCGAGTGAGGAACCTGTTC AATGTGGTGGACTGCAAGCTCCATTGGCAGAAGAACGGAGACTACTTGTGTGTGAAAGTAGATAGGACTCCGAAAGGCACCCAGGGTGTT GTCACAAATTTTGAAATTTTCCGAATGAGGGAGAAACAGGTACCTGTGGATGTGGTCGAGATGAAAGAAACCATCATAGCCTTTGCCTGG GAACCAAATGGAAGTAAGTTTGCTGTGCTGCACGGAGAGGCTCCGCGGATATCTGTGTCTTTCTACCACGTCAAAAACAACGGGAAGATT GAACTCATCAAGATGTTCGACAAGCAGCAGGCGAACACCATCTTCTGGAGCCCCCAAGGACAGTTCGTGGTGTTGGCGGGCCTGAGGAGT ATGAACGGTGCCTTAGCGTTTGTGGACACTTCGGACTGCACGGTCATGAACATCGCAGAGCACTACATGGCTTCCGACGTCGAATGGGAT CCTACTGGGCGCTACGTCGTCACCTCTGTGTCCTGGTGGAGCCATAAGGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGCCTC CTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAAATT AAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGAAGG CGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGAGGA GGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAA GGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTT GCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATAT GGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTAT ATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAATTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAG CTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCCAGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAG AACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAGTCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTT GCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAACTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCT TTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACCTCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTT ATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATGACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_EIF3B_ENST00000360876_chr7_2418877_+_GDI2_ENST00000380191_chr10_5828013_-_4130nt GGGAGAGTCGGAAGCGCGGCGGCCGCGGAGCCCTGCGAGTAGGCAGCGTTGGGCCCATGCAGGACGCGGAGAACGTGGCGGTGCCCGAGG CGGCCGAGGAGCGCGCCGAGCCCGGCCAGCAGCAGCCGGCCGCCGAGCCGCCGCCAGCCGAGGGGCTGCTGCGGCCCGCGGGGCCCGGCG CTCCGGAGGCCGCGGGGACCGAGGCCTCCAGTGAGGAGGTGGGGATCGCGGAGGCCGGGCCGGAGTCCGAGGTGAGGACCGAGCCGGCGG CCGAGGCAGAGGCGGCCTCCGGCCCGTCCGAGTCGCCCTCGCCGCCGGCCGCCGAGGAGCTGCCCGGGTCGCATGCTGAGCCCCCTGTCC CGGCACAGGGCGAGGCCCCAGGAGAGCAGGCTCGGGACGAGCGCTCCGACAGCCGGGCCCAGGCGGTGTCCGAGGACGCGGGAGGAAACG AGGGCAGAGCGGCCGAGGCCGAACCCCGGGCGCTGGAGAACGGCGACGCGGACGAGCCCTCCTTCAGCGACCCCGAGGACTTCGTGGACG ACGTGAGCGAGGAAGAATTACTGGGAGATGTACTCAAAGATCGGCCCCAGGAAGCAGATGGAATCGATTCGGTGATTGTAGTGGACAATG TCCCTCAGGTGGGACCCGACCGACTTGAGAAACTCAAAAATGTCATCCACAAGATCTTTTCCAAGTTTGGGAAAATCACAAATGATTTTT ATCCTGAAGAGGATGGGAAGACAAAAGGGTATATTTTCCTGGAGTACGCGTCCCCTGCCCACGCTGTGGATGCTGTGAAGAACGCCGACG GCTACAAGCTTGACAAGCAGCACACATTCCGGGTCAACCTCTTTACGGATTTTGACAAGTATATGACGATCAGTGACGAGTGGGATATTC CAGAGAAACAGCCTTTCAAAGACCTGGGGAACTTACGTTACTGGCTTGAAGAGGCAGAATGCAGAGATCAGTACAGTGTGATTTTTGAGA GTGGAGACCGCACTTCCATATTCTGGAATGACGTAAAAGACCCTGTCTCAATTGAAGAAAGAGCGAGATGGACAGAGACGTATGTGCGTT GGTCTCCTAAGGGCACCTACCTGGCTACCTTTCATCAAAGAGGCATTGCTCTATGGGGGGGAGAGAAATTCAAGCAAATTCAGAGATTCA GCCACCAAGGGGTTCAGCTTATTGACTTCTCACCTTGTGAAAGGTACCTGGTGACCTTTAGCCCCCTGATGGACACGCAGGATGACCCTC AGGCCATAATCATCTGGGACATCCTTACGGGGCACAAGAAGAGGGGTTTTCACTGTGAGAGCTCAGCCCATTGGCCTATTTTTAAGTGGA GCCATGATGGCAAATTCTTTGCCAGAATGACCCTGGATACGCTTAGCATCTATGAAACTCCTTCTATGGGTCTTTTGGACAAGAAGAGTT TGAAGATCTCTGGGATAAAAGACTTTTCTTGGTCTCCTGGTGGTAACATAATCGCCTTCTGGGTGCCTGAAGACAAAGATATTCCAGCCA GGGTAACCCTGATGCAGCTCCCTACCAGGCAAGAGATCCGAGTGAGGAACCTGTTCAATGTGGTGGACTGCAAGCTCCATTGGCAGAAGA ACGGAGACTACTTGTGTGTGAAAGTAGATAGGACTCCGAAAGGCACCCAGGGTGTTGTCACAAATTTTGAAATTTTCCGAATGAGGGAGA AACAGGTACCTGTGGATGTGGTCGAGATGAAAGAAACCATCATAGCCTTTGCCTGGGAACCAAATGGAAGTAAGTTTGCTGTGCTGCACG GAGAGGCTCCGCGGATATCTGTGTCTTTCTACCACGTCAAAAACAACGGGAAGATTGAACTCATCAAGATGTTCGACAAGCAGCAGGCGA ACACCATCTTCTGGAGCCCCCAAGGACAGTTCGTGGTGTTGGCGGGCCTGAGGAGTATGAACGGTGCCTTAGCGTTTGTGGACACTTCGG ACTGCACGGTCATGAACATCGCAGAGCACTACATGGCTTCCGACGTCGAATGGGATCCTACTGGGCGCTACGTCGTCACCTCTGTGTCCT GGTGGAGCCATAAGGTGGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGC TGCTGTGGCGGCCCCGGCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTG AACAGAAGGATCGTTTGAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGA AAATGGCCCAGGAGCTCTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGAGGAGGCCTAATGGGATTGTTTGAAAAACGTCGCTTCA GGAAATTCCTAGTGTATGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATG TGTATAAGAAATTTGATTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAAC CGTGTTATGAAACCATTAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCC TTGGAGAACTGCCCCAAGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTAC AGAATGGAAAAGTAATTGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGG TAGAAAAAGTGGGCCAGGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCAACTCCTGCCAGATCATTA TTCCACAGAACCAAGTCAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAAGGGAAGTACATTG CTATAGTTAGTACAACTGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTG TTAGCATCAGTGACCTCCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCCACCACTCATTTTG AGACAACGTGTGATGACATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACA TCTATGGGGAAGACTAACAGCAGTACATGTTATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGCATATAATGAAATCAATAT TGTAAGGCCTGCTTTTGTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTAATTATTAACTTGT TTTCATGGAGTGGCTATTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACA AACATTGGGATACCGACACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGA TCCATACAGGTTGTGTGTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGCATCCGGAAGTTTT CCCTATGACTTTATATTTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATGTGGGCATAAAATT CTAACCAAACCCCAGACATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAG GAAGCGAACATAAAGCGGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGAC >In-frame_EIF3B_ENST00000397011_chr7_2418877_+_GDI2_ENST00000380191_chr10_5828013_-_4114nt CGGCGGCCGCGGAGCCCTGCGAGTAGGCAGCGTTGGGCCCATGCAGGACGCGGAGAACGTGGCGGTGCCCGAGGCGGCCGAGGAGCGCGC CGAGCCCGGCCAGCAGCAGCCGGCCGCCGAGCCGCCGCCAGCCGAGGGGCTGCTGCGGCCCGCGGGGCCCGGCGCTCCGGAGGCCGCGGG GACCGAGGCCTCCAGTGAGGAGGTGGGGATCGCGGAGGCCGGGCCGGAGTCCGAGGTGAGGACCGAGCCGGCGGCCGAGGCAGAGGCGGC CTCCGGCCCGTCCGAGTCGCCCTCGCCGCCGGCCGCCGAGGAGCTGCCCGGGTCGCATGCTGAGCCCCCTGTCCCGGCACAGGGCGAGGC CCCAGGAGAGCAGGCTCGGGACGAGCGCTCCGACAGCCGGGCCCAGGCGGTGTCCGAGGACGCGGGAGGAAACGAGGGCAGAGCGGCCGA GGCCGAACCCCGGGCGCTGGAGAACGGCGACGCGGACGAGCCCTCCTTCAGCGACCCCGAGGACTTCGTGGACGACGTGAGCGAGGAAGA ATTACTGGGAGATGTACTCAAAGATCGGCCCCAGGAAGCAGATGGAATCGATTCGGTGATTGTAGTGGACAATGTCCCTCAGGTGGGACC CGACCGACTTGAGAAACTCAAAAATGTCATCCACAAGATCTTTTCCAAGTTTGGGAAAATCACAAATGATTTTTATCCTGAAGAGGATGG GAAGACAAAAGGGTATATTTTCCTGGAGTACGCGTCCCCTGCCCACGCTGTGGATGCTGTGAAGAACGCCGACGGCTACAAGCTTGACAA GCAGCACACATTCCGGGTCAACCTCTTTACGGATTTTGACAAGTATATGACGATCAGTGACGAGTGGGATATTCCAGAGAAACAGCCTTT CAAAGACCTGGGGAACTTACGTTACTGGCTTGAAGAGGCAGAATGCAGAGATCAGTACAGTGTGATTTTTGAGAGTGGAGACCGCACTTC CATATTCTGGAATGACGTAAAAGACCCTGTCTCAATTGAAGAAAGAGCGAGATGGACAGAGACGTATGTGCGTTGGTCTCCTAAGGGCAC CTACCTGGCTACCTTTCATCAAAGAGGCATTGCTCTATGGGGGGGAGAGAAATTCAAGCAAATTCAGAGATTCAGCCACCAAGGGGTTCA GCTTATTGACTTCTCACCTTGTGAAAGGTACCTGGTGACCTTTAGCCCCCTGATGGACACGCAGGATGACCCTCAGGCCATAATCATCTG GGACATCCTTACGGGGCACAAGAAGAGGGGTTTTCACTGTGAGAGCTCAGCCCATTGGCCTATTTTTAAGTGGAGCCATGATGGCAAATT CTTTGCCAGAATGACCCTGGATACGCTTAGCATCTATGAAACTCCTTCTATGGGTCTTTTGGACAAGAAGAGTTTGAAGATCTCTGGGAT AAAAGACTTTTCTTGGTCTCCTGGTGGTAACATAATCGCCTTCTGGGTGCCTGAAGACAAAGATATTCCAGCCAGGGTAACCCTGATGCA GCTCCCTACCAGGCAAGAGATCCGAGTGAGGAACCTGTTCAATGTGGTGGACTGCAAGCTCCATTGGCAGAAGAACGGAGACTACTTGTG TGTGAAAGTAGATAGGACTCCGAAAGGCACCCAGGGTGTTGTCACAAATTTTGAAATTTTCCGAATGAGGGAGAAACAGGTACCTGTGGA TGTGGTCGAGATGAAAGAAACCATCATAGCCTTTGCCTGGGAACCAAATGGAAGTAAGTTTGCTGTGCTGCACGGAGAGGCTCCGCGGAT ATCTGTGTCTTTCTACCACGTCAAAAACAACGGGAAGATTGAACTCATCAAGATGTTCGACAAGCAGCAGGCGAACACCATCTTCTGGAG CCCCCAAGGACAGTTCGTGGTGTTGGCGGGCCTGAGGAGTATGAACGGTGCCTTAGCGTTTGTGGACACTTCGGACTGCACGGTCATGAA CATCGCAGAGCACTACATGGCTTCCGACGTCGAATGGGATCCTACTGGGCGCTACGTCGTCACCTCTGTGTCCTGGTGGAGCCATAAGGT GGACAACGCGTACTGGCTGTGGACTTTCCAGGGACGCCTCCTGCAGAAGAACAACAAGGACCGCTTCTGCCAGCTGCTGTGGCGGCCCCG GCCTCCCACACTCCTGAGCCAGGAACAGATCAAGCAAATTAAAAAGGATCTGAAGAAATACTCTAAGATCTTTGAACAGAAGGATCGTTT GAGTCAGTCCAAAGCCTCAAAGGAATTGGTGGAGAGAAGGCGCACCATGATGGAAGATTTCCGGAAGTACCGGAAAATGGCCCAGGAGCT CTATATGGAGCAGAAAAACGAGCGCCTGGAGTTGCGAGGAGGCCTAATGGGATTGTTTGAAAAACGTCGCTTCAGGAAATTCCTAGTGTA TGTTGCCAACTTCGATGAAAAAGATCCAAGAACTTTTGAAGGCATTGATCCTAAGAAGACCACAATGCGAGATGTGTATAAGAAATTTGA TTTGGGTCAAGACGTTATAGATTTTACTGGTCATGCTCTTGCACTTTACAGAACTGATGATTACTTAGATCAACCGTGTTATGAAACCAT TAATAGAATTAAACTTTACAGTGAATCTTTGGCAAGATATGGCAAAAGCCCATACCTTTATCCACTCTATGGCCTTGGAGAACTGCCCCA AGGATTTGCAAGGCTAAGTGCTATTTATGGAGGTACCTATATGCTGAATAAACCCATTGAAGAAATCATTGTACAGAATGGAAAAGTAAT TGGTGTAAAATCTGAAGGAGAAATTGCTCGCTGTAAGCAGCTCATCTGTGACCCCAGCTACGTAAAAGATCGGGTAGAAAAAGTGGGCCA GGTGATCAGAGTTATTTGCATCCTCAGCCACCCCATCAAGAACACCAATGATGCCAACTCCTGCCAGATCATTATTCCACAGAACCAAGT CAATCGAAAGTCAGATATCTACGTCTGCATGATCTCCTTTGCGCACAATGTAGCAGCACAAGGGAAGTACATTGCTATAGTTAGTACAAC TGTGGAAACCAAGGAGCCTGAGAAGGAAATCAGACCAGCTTTGGAGCTCTTGGAACCAATTGAACAGAAATTTGTTAGCATCAGTGACCT CCTGGTACCAAAAGACTTGGGAACAGAAAGCCAGATCTTTATTTCCCGCACATATGATGCCACCACTCATTTTGAGACAACGTGTGATGA CATTAAAAACATCTATAAGAGGATGACAGGATCAGAGTTTGACTTTGAGGAAATGAAGCGCAAGAAGAATGACATCTATGGGGAAGACTA ACAGCAGTACATGTTATTATGTAATTAGGACACATTTAAAATTTGGCAAATAATGCATATAATGAAATCAATATTGTAAGGCCTGCTTTT GTAATGAAAATGGAGAGAATGAAGAGCGCTGTGCCAGTAAATACTCCCCTTCACCTTTCTAATTATTAACTTGTTTTCATGGAGTGGCTA TTCAGCATTGGCAGTTACCACATTCTGTTCAATTTAACCAAACTGGCTTTTTTTTTTTCTAGTGAAGTTAAACAAACATTGGGATACCGA CACAGACAACTTGAGACAGTTTTTTTAATCTTTTAATCAGTGTAGCTATGTGCTGCTGCTGCTCAAGAGCTGGATCCATACAGGTTGTGT GTCATCTGTCCTCTTGAGGTTCAGGAGATTCTAAATTGAATATTCCACGGTTTGGGACAGCATCCGGAAGTTTTCCCTATGACTTTATAT TTTGTATTATGTCAAATGTTATGGCAGGGCCCAAATAGCATAGCCACAAGTTTGGTTTATGTGGGCATAAAATTCTAACCAAACCCCAGA CATAGGGAGTCATTTGGAGAAAGCCTGTATGTGGTGTTTTAACCTAATAAAGTTGATGAGAGAGAAGGGGAGAGGAAGCGAACATAAAGC GGGTCAAGTGTAGTGCATCTTTTGTATCTCAGGCGTGGCTTCTTCAGTGGACCAAGCTGCAATGCAGTATTGACTTGACAGAGCCTCTAC |
Top |
FusionGenePPI for EIF3B_GDI2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| EIF3B | EIF3A, EIF4A1, EIF4B, EIF4E, EIF4G1, MTOR, RPS6, RPS6KB1, EIF6, EIF3C, EIF3I, EIF3J, RPTOR, EIF3G, EIF3H, EIF3F, USP3, SRRM2, TADA2A, CD4, HDAC5, EIF3E, EIF3K, EIF3L, EIF3M, RAD21, EIF3D, EIF5, RPLP0P6, BRCA1, SMURF1, DDX3X, FN1, VCAM1, UPF1, ITGA4, PAN2, CD81, IGSF8, ICAM1, FBXO6, TARDBP, DYNC1I2, MCM4, CSNK2A2, RIOK2, STAU1, NCBP1, MDM2, CCDC8, EED, RNF2, RSPH9, RPS6KB2, PAIP1, ATL3, ATP6V0D1, ATP1A1, EIF3CL, MRPL40, MSH2, VAPA, NTRK1, EIF4G3, HERC2, AHSA1, MYO1C, GAN, MCM2, CDC37, ZNF746, EGFR, CYLD, DLD, DNM1L, PARK7, G3BP1, CCND2, YAP1 | GDI2 | RAB11A, RAB9A, RAB5A, RAB4A, RAB2A, RAB8A, RAB24, ELAVL1, SIRT7, ISG15, RAB11B, RAB1A, AIP, SMURF1, FN1, IQCB1, BAG3, GLRA2, DUT, HUWE1, RAB1B, RAB31, RASSF10, HSPB1, UNK, CLIC3, EZR, FH, ARHGDIG, RAB10, RAB8B, WDFY2, PLIN3, PREP, RAB7A, RDX, STIP1, STMN1, TAGLN3, TXNDC5, SKA3, MCM2, U2AF2, C10orf88, GDI1, RAB5C, H2AFY, RAB3A, RAB6B, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for EIF3B_GDI2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for EIF3B_GDI2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | EIF3B | C0019693 | HIV Infections | 1 | CTD_human |
| Tgene | GDI2 | C0279626 | Squamous cell carcinoma of esophagus | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|