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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 10978

FusionGeneSummary for EEF1G_NXF1

check button Fusion gene summary
Fusion gene informationFusion gene name: EEF1G_NXF1
Fusion gene ID: 10978
HgeneTgene
Gene symbol

EEF1G

NXF1

Gene ID

1937

10482

Gene nameeukaryotic translation elongation factor 1 gammanuclear RNA export factor 1
SynonymsEF1G|GIG35MEX67|TAP
Cytomap

11q12.3

11q12.3

Type of geneprotein-codingprotein-coding
Descriptionelongation factor 1-gammaEF-1-gammaPRO1608eEF-1B gammapancreatic tumor-related proteintranslation elongation factor eEF-1 gamma chainnuclear RNA export factor 1mRNA export factor TAPtip associating proteintip-associated protein
Modification date2018052320180523
UniProtAcc

P26641

Q9UBU9

Ensembl transtripts involved in fusion geneENST00000329251, ENST00000378019, 
ENST00000532986, 
ENST00000531709, 
ENST00000294172, ENST00000532297, 
ENST00000533048, ENST00000531131, 
ENST00000439713, 
Fusion gene scores* DoF score4 X 3 X 3=365 X 5 X 4=100
# samples 45
** MAII scorelog2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EEF1G [Title/Abstract] AND NXF1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneNXF1

GO:0006406

mRNA export from nucleus

19165146


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVSKCMTCGA-EE-A20F-06AEEF1Gchr11

62334278

-NXF1chr11

62563817

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000329251ENST00000531709EEF1Gchr11

62334278

-NXF1chr11

62563817

-
5CDS-3UTRENST00000329251ENST00000294172EEF1Gchr11

62334278

-NXF1chr11

62563817

-
5CDS-3UTRENST00000329251ENST00000532297EEF1Gchr11

62334278

-NXF1chr11

62563817

-
5CDS-5UTRENST00000329251ENST00000533048EEF1Gchr11

62334278

-NXF1chr11

62563817

-
5CDS-intronENST00000329251ENST00000531131EEF1Gchr11

62334278

-NXF1chr11

62563817

-
5CDS-intronENST00000329251ENST00000439713EEF1Gchr11

62334278

-NXF1chr11

62563817

-
5CDS-3UTRENST00000378019ENST00000531709EEF1Gchr11

62334278

-NXF1chr11

62563817

-
5CDS-3UTRENST00000378019ENST00000294172EEF1Gchr11

62334278

-NXF1chr11

62563817

-
5CDS-3UTRENST00000378019ENST00000532297EEF1Gchr11

62334278

-NXF1chr11

62563817

-
5CDS-5UTRENST00000378019ENST00000533048EEF1Gchr11

62334278

-NXF1chr11

62563817

-
5CDS-intronENST00000378019ENST00000531131EEF1Gchr11

62334278

-NXF1chr11

62563817

-
5CDS-intronENST00000378019ENST00000439713EEF1Gchr11

62334278

-NXF1chr11

62563817

-
intron-3UTRENST00000532986ENST00000531709EEF1Gchr11

62334278

-NXF1chr11

62563817

-
intron-3UTRENST00000532986ENST00000294172EEF1Gchr11

62334278

-NXF1chr11

62563817

-
intron-3UTRENST00000532986ENST00000532297EEF1Gchr11

62334278

-NXF1chr11

62563817

-
intron-5UTRENST00000532986ENST00000533048EEF1Gchr11

62334278

-NXF1chr11

62563817

-
intron-intronENST00000532986ENST00000531131EEF1Gchr11

62334278

-NXF1chr11

62563817

-
intron-intronENST00000532986ENST00000439713EEF1Gchr11

62334278

-NXF1chr11

62563817

-

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FusionProtFeatures for EEF1G_NXF1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EEF1G

P26641

NXF1

Q9UBU9

Probably plays a role in anchoring the complex to othercellular components. Involved in the nuclear export of mRNA species bearingretroviral constitutive transport elements (CTE) and in the exportof mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway)(PubMed:10924507). The NXF1-NXT1 heterodimer is involved in theexport of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5components of the TREX complex (PubMed:18364396, PubMed:19165146,PubMed:9660949). ALYREF/THOC4-bound mRNA is thought to betransferred to the NXF1-NXT1 heterodimer for export(PubMed:18364396, PubMed:19165146, PubMed:9660949). Also involvedin nuclear export of m6A-containing mRNAs: interaction betweenSRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to bothSRSF3 and NXF1, promoting mRNA nuclear export (PubMed:28984244).{ECO:0000269|PubMed:10924507, ECO:0000269|PubMed:18364396,ECO:0000269|PubMed:19165146, ECO:0000269|PubMed:28984244,ECO:0000269|PubMed:9660949}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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FusionGeneSequence for EEF1G_NXF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for EEF1G_NXF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
EEF1GEEF1DP3, EEF1D, EEF1B2, ILF2, ABCC9, EEF1G, ADAP2, CHFR, CXCL13, HDAC5, FAM195A, MVD, EFNA1, OGFOD2, FOXG1, C1orf174, NUP85, PLEKHA4, PHACTR3, ARF1, CBX8, CRELD1, DKC1, FEN1, ENOX1, NADK, NCK2, RPS28, SNAPIN, SNRPD2, TP53I3, TRIB3, GET4, MED31, ECH1, RECQL5, GSTO1, HMOX2, KARS, RPL4P5, PDCD5, PSMD11, RGL2, WDR33, ARIH2, CCT7, CDC42, CDK5RAP2, CSTF2, DLEU1, HNRNPH3, CCDC106, PTPN4, PTPRS, SAT1, TUBB3, ZNF24, VARS, LZTS1, CARS, LARS, HARS, EGFR, MYC, UCHL5, SNW1, AGO4, YWHAG, SIRT1, NUDT21, GSK3B, ZBED8, NUDT3, PTK2, TNNT1, AKT1, CDK2AP2, GADD45A, C11orf58, NDRG1, ISG15, CUL3, CUL2, CDK2, CUL1, COPS5, CAND1, NEDD8, GADD45G, GRB2, EEF1A1, RPL5, RPL8, HNRNPA3, SNRPA1, SRSF9, PLOD3, FLNC, STRIP1, SMURF1, YWHAE, FN1, VCAM1, MTNR1A, SKIL, MLH1, PAN2, IGSF8, NPM1, RAD52, ADRB2, FBXO6, TARDBP, TRAP1, CCT3, SHFM1, STAU1, TRIM63, TRIM55, FUS, RBM6, KLHL18, PLGRKT, ZDHHC17, CUL7, OBSL1, CCDC8, EED, SUMO2, SIRT6, ABL1, KTN1, INPPL1, EEF1A2, MKKS, RPS6KB2, HNRNPA1, ATL3, GTF2E1, GTF2E2, NACA, NPM3, PABPC1, RANGAP1, RPL38, IPO4, PRPF38B, NTRK1, ERBB2, EXOSC9, PKN2, SLC33A1, KIF20B, CHMP4B, MCM2, CDC73, WWP2, CDH1, CYLD, DLD, DLST, DNM1L, HSD17B10, PARK7, PDHA1, SDHA, SOAT1, SOD1, VDAC1, TRIM25, BRCA1NXF1NXT1, ELAVL4, RBM8A, MAGOH, DHX9, NUP214, NUP98, U2AF1, TNPO2, RAN, EIF4A3, SIRT7, SLC26A8, GTF2B, CUL3, CUL1, COPS5, CAND1, KPNB1, TNPO1, IPO4, IPO11, IMPA1, RANBP2, NUP205, NUP188, HNRNPUL1, NUP93, NUP88, RANGAP1, RAE1, UBE2K, XPO1, UBQLN4, XIST, SRSF7, SRSF1, SRSF2, NXF1, NXF2, NXF3, NXF5, FYTTD1, UPF3A, UPF3B, RNPS1, NUTF2, RBM15B, RBM15, SH2D3A, THOC5, ALYREF, TPR, LUC7L3, SON, HNRNPK, EBNA1BP2, RBMX, HP1BP3, DHX15, DDB1, DDX19A, HNRNPC, EIF2A, ILF3, CSNK2A1, NUP62, ESRRA, RAD51, TRA2B, SGTA, TRA2A, KCTD5, ZBED2, TARDBP, DVL3, GFAP, TP53BP2, MID2, LDOC1, TIFA, KRT40, NOC2L, AGRN, PARK7, PGD, DFFA, SRM, EXOSC10, MTOR, MAD2L2, MFN2, SZRD1, UBR4, PQLC2, MINOS1, DDOST, CEP85, ARID1A, GPN2, NUDC, TMEM222, RCC1, SNRNP40, TXLNA, YARS, SFPQ, ZMYM4, AGO1, LSM10, C1orf109, KIAA0754, BMP8B, NFYC-AS1, ELOVL1, MED8, KDM4A, IPO13, ATP6V0B, KIF2C, UROD, GPBP1L1, LRRC41, CMPK1, NRD1, LRP8, YIPF1, LRRC42, MRPL37, PCSK9, DOCK7, PDE4B, WLS, DDAH1, ODF2L, LMO4, CCBL2, ZNF644, FNBP1L, ABCD3, RWDD3, PALMD, AGL, DPH5, ATXN7L2, GNAI3, GSTM3, AHCYL1, STRIP1, LAMTOR5, FAM212B, CAPZA1, BCAS2, NOTCH2NL, LIX1L, APH1A, MRPS21, MCL1, SETDB1, PRUNE, CDC42SE1, PIP5K1A, RFX5, POGZ, S100A11, S100A4, S100A16, CHTOP, SLC39A1, CREB3L4, TPM3, C1orf43, UBAP2L, PYGO2, SHC1, FLAD1, EFNA4, FDPS, KIAA0907, ARHGEF2, SSR2, LMNA, SMG5, MEF2D, NES, MRPL24, HDGF, TAGLN2, COPA, DEDD, NDUFS2, TOMM40L, DCAF6, RABGAP1L, CEP350, STX6, C1orf21, PLA2G4A, ZNF281, DDX59, MAPKAPK2, SMYD2, EPRS, EPHX1, LIN9, PARP1, JMJD4, GUK1, OBSCN, RNF187, TOMM20, B3GALNT2, MTR, AHCTF1, CPSF3, CENPO, SNX17, WDR43, FAM98A, LRPPRC, CAMKMT, SRBD1, PNPT1, EFEMP1, SMYD5, CCT7, DCTN1, POLR1A, RPIA, MRPS5, COX5B, BUB1, ANAPC1, TTL, SLC20A1, ACTR3, BIN1, ERCC3, IWS1, PTPN18, ARHGEF4, KYNU, PKP4, TANC1, ITGA6, ATP5G3, NAB1, ANKRD44, HSPD1, ABI2, EEF1B2, CCNYL1, IDH1, TMBIM1, ZNF142, TTLL4, TUBA4A, FARSB, SP100, PSMD1, ATG16L1, HJURP, ATG4B, ING5, SETD5, ARPC4, ARPC4-TTLL3, TATDN2, RAF1, SH3BP5, PLCL2, ZNF860, CLASP2, SNORA6, CTNNB1, SCAP, SMARCC1, DHX30, CDC25A, CCDC51, TREX1, PFKFB4, COL7A1, UQCRC1, QRICH1, QARS, APEH, RNF123, RBM6, RBM5, SEMA3F, IFRD2, NPRL2, ALAS1, ARHGEF3, THOC7, MAGI1, MINA, PCNP, ZBTB11, KIAA1524, DZIP3, B4GALT4, PDIA5, UMPS, ZXDC, SEC61A1, RUVBL1, EEFSEC, ISY1, MBD4, PIK3R4, RYK, ANAPC13, PCCB, HPS3, RNF13, MFSD1, ACTL6A, YEATS2, ABCC5, ABCF3, PSMD2, ETV5, TBCCD1, LSG1, XXYLT1, FGFRL1, NELFA, NOP14, EVC, AFAP1, WDR1, HSP90AB2P, ATP10D, OCIAD1, GRSF1, CCNI, HNRNPD, SEC31A, COPS4, WDFY3, HERC3, HADH, RPL34, FAT4, FBXW7, ETFDH, HMGB2, SLC25A4, SDHA, PDCD6, NDUFS6, ANKRD33B, DROSHA, ZFR, SKP2, MARVELD2, MRPS27, PTCD2, AGGF1, SCAMP1, NR2F1-AS1, ERAP1, FER, SNORA13, RAPGEF6, HSPA4, VDAC1, H2AFY, CDC23, HSPA9, PAIP2, ANKHD1, ANKHD1-EIF4EBP3, WDR55, HARS, HARS2, GNPDA1, FBXO38, PCYOX1L, SYNPO, GALNT10, GEMIN5, MRPL22, ZBED8, SLU7, CCNG1, WWC1, RANBP17, NPM1, STK10, BOD1, UIMC1, LMAN2, PDLIM7, DDX41, TMED9, HNRNPAB, SQSTM1, EXOC2, NQO2, FARS2, RNF144B, HIST1H4E, HIST1H2BG, HIST1H2AE, DDR1, CSNK2B, ABHD16A, EHMT2, ATF6B, AGPAT1, TAPBP, NUDT3, SNRPC, ZNF76, NFYA, MRPS10, TRERF1, KLHDC3, XPO5, POLH, HSP90AB1, EEF1A1, MYO6, TTK, SNX14, PNISR, ASCC3, SESN1, CDC40, GTF3C6, RPF2, HDAC2, KPNA5, GOPC, BCLAF1, IFNGR1, TNFAIP3, FBXO30, RAB32, FBXO5, SCAF8, MRPL18, DNAAF5, SNX8, RNF216P1, RNF216, KLHL7, OSBPL3, HNRNPA2B1, KBTBD2, TMED4, OGDH, SNORA5A, TNS3, LANCL2, GBAS, CRCP, ADAM22, KRIT1, GATAD1, PTCD1, ATP5J2-PTCD1, MCM7, PMPCB, PSMC2, NAMPT, TES, CAV1, LINC01000, TNPO3, KLHDC10, PODXL, SLC35B4, LOC155060, SLC4A2, ABCF2, SH2D4A, XPO7, DMTN, CHMP7, R3HCC1, SCARA3, CCDC25, ESCO2, PBK, SARAF, GTF2E2, UBXN8, BAG4, AGPAT6, SLC20A2, MCM4, SNAI2, MRPL15, MTFR1, VCPIP1, STAU2, GDAP1, TPD52, RIPK2, DECR1, DPY19L4, YWHAZ, DEPTOR, ATAD2, NDUFB9, TRAPPC9, ZC3H3, SCRIB, CPSF1, C8orf33, KANK1, KIAA0020, RCL1, KDM4C, MPDZ, CDKN2A, ACO1, TAF1L, NFX1, NOL6, UBAP1, SIGMAR1, TLN1, GRHPR, EXOSC3, ANXA1, C9orf40, CEP78, CTSL, ROR2, NOL8, FAM120A, NANS, SLC31A1, POLE3, ZNF618, ARPC5L, HSPA5, GAPVD1, AK1, ST6GALNAC4, SLC25A25, SLC27A4, URM1, CCBL1, PPP2R4, FNBP1, EXOSC2, RAPGEF1, TSC1, SURF6, SURF1, SURF4, REXO4, PPP1R26, TMEM141, RABL6, ABCA2, DPH7, WDR37, ASB13, SFMBT2, USP6NL, ACBD5, CUL2, BMS1, SLC16A9, HERC4, HNRNPH3, DNA2, SAR1A, ANXA7, SEC24C, CPEB3, PDLIM1, ALDH18A1, TCTN3, GOT1, NDUFB8, SFXN3, BTRC, C10orf76, NOLC1, NFKB2, ACTR1A, XPNPEP1, ZDHHC6, SFXN4, GRK5, BAG3, MCMBP, ZRANB1, ECHS1, AP2A2, NAP1L4, DNHD1, ILK, CTR9, COPB1, TSG101, RCN1, DEPDC7, PDHX, LDLRAD3, COMMD9, CRY2, PSMC3, NDUFS3, FNBP4, CTNND1, FAM111B, OSBP, PRPF19, CPSF7, DAGLA, FEN1, AHNAK, UBXN1, SNHG1, SNORD22, PLCB3, MRPL49, EIF1AD, SYT12, RPS6KB2, UNC93B1, CPT1A, CCND1, NUMA1, INPPL1, PDE2A, ARHGEF17, RELT, P4HA3, XRRA1, RPS3, C11orf30, ALG8, PCF11, CREBZF, ANKRD49, AMOTL1, ENDOD1, YAP1, AASDHPPT, CUL5, BACE1, HYOU1, VPS11, HINFP, USP2, TRIM29, RPUSD4, FOXRED1, ARHGAP32, NCAPD3, VPS26B, MLF2, USP5, CLSTN3, PEX5, M6PR, GABARAPL1, WBP11, STRAP, ITPR2, PPFIBP1, IPO8, CPNE8, KIF21A, PPHLN1, HDAC7, PFKM, ASB8, LIMA1, LETMD1, ZNF740, ESPL1, SP1, TARBP2, HOXC10, WIBG, RAB5B, SMARCC2, ANKRD52, CS, RBMS2, PRIM1, DCTN2, USP15, PPM1H, MSRB3, CCT2, KRR1, RASSF9, NTN4, SLC25A3, TDG, CKAP4, POLR3B, MVK, ATXN2, RBM19, FBXO21, PEBP1, PXN, COQ5, RNF10, UNC119B, RHOF, UBC, STX2, MPHOSPH8, XPO4, CENPJ, LNX2, USPL1, EXOSC8, MED4, INTS6, VPS36, DIAPH3, PIBF1, MBNL2, RAP2A, TMTC4, TPP2, RAB20, CARKD, ANKRD10, TUBGCP3, PCID2, CDC16, PNP, SUPT16H, CHD8, OXA1L, HAUS4, PSMB5, CDH24, SCFD1, POLE2, SLC39A9, RBM25, FLVCR2, CIPC, SNW1, ADCK1, CEP128, EFCAB11, CALM1, DDX24, HSP90AA1, INF2, BTBD6, ARHGAP11A, AVEN, EMC4, AQR, FAM98B, KNSTRN, CHP1, ZNF106, HAUS2, UBR1, ADAL, ZSCAN29, TP53BP1, SPATA5L1, GABPB1-AS1, TCF12, MYO1E, BNIP2, SNX1, OAZ2, MAP2K5, KIF23, MYO9A, ULK3, SIN3A, PTPN9, TMED3, FANCI, IQGAP1, SNRNP25, NME4, STUB1, JMJD8, NTHL1, MLST8, ZSCAN32, CLUAP1, TRAP1, ANKS3, ALG1, TXNDC11, NDE1, NOMO2, ARHGAP17, NFATC2IP, KIF22, MAZ, CD2BP2, DCTPP1, SEPHS2, RNF40, SHCBP1, VPS35, RPGRIP1L, FAM192A, ARL2BP, E2F4, EDC4, PSKH1, NFATC3, CHTF8, CYB5B, NQO1, WWP2, PDPR, AARS, ZNF23, DHX38, RFWD3, ADAT1, CDYL2, MBTPS1, WFDC1, ZDHHC7, EMC8, MTHFSD, KLHDC4, ZC3H18, RPL13, CHMP1A, ABR, INPP5K, PRPF8, WDR81, DPH1, CTDNEP1, POLR2A, SENP3, MPDU1, CHD3, PFAS, TRIM16, FAM83G, SPECC1, USP22, TNFAIP1, POLDIP2, ALDOC, RAB34, MYO18A, NF1, COPRS, RHOT1, ZNF207, LIG3, RAD51D, AATF, ACACA, DUSP14, C17orf96, ERBB2, MIEN1, PSMD3, THRA, MSL1, CASC3, SMARCE1, NT5C3B, RAB5C, STAT3, MLX, FAM134C, PSME3, DHX8, MEOX1, ASB16-AS1, SLC25A39, GRN, KIF18B, NMT1, HEXIM1, UBE2Z, IGF2BP1, ANKRD40, TOB1, SUPT4H1, CLTC, RNFT1, DDX42, DDX5, CEP95, PRKCA, HELZ, KPNA2, FAM104A, GGA3, LOC100287042, SLC25A19, TSEN54, SAP30BP, EXOC7, UBE2O, MXRA7, JMJD6, CANT1, TBC1D16, RPTOR, NPLOC4, HGS, SLC25A10, USP14, NDC80, MTCL1, TUBB6, CEP192, FAM210A, ROCK1, GREB1L, TTC39C, GALNT1, RPRD1A, ELP2, TPGS2, ATP5A1, MBD1, PIGN, TNFRSF11A, VPS4B, ADNP2, PTBP1, CIRBP, MEX3D, UBXN6, C19orf10, RANBP3, PNPLA6, LRRC8E, HNRNPM, ZNF558, TYK2, CDC37, MAN2B1, PRKACA, ASF1B, AKAP8, EPS15L1, BABAM1, PIK3R2, RFXANK, UQCRFS1, PEPD, ZNF383, SUPT5H, FBL, PSMC4, ZNF780A, CCDC97, ATP5SL, MEGF8, VASP, OPA3, PPP5C, CALM3, STRN4, GRWD1, RUVBL2, TEAD2, PIH1D1, PRMT1, ZNF761, ISOC2, EPN1, ZNF460, ZNF544, ZNF8, RPS5, ZNF324, NOP56, IDH3B, ITPA, C20orf194, ESF1, XRN2, APMAP, POFUT1, KIF3B, E2F1, RALY, CEP250, RBM12, RBM39, PHF20, LINC00657, DLGAP4, TGIF2-C20orf24, C20orf24, DSN1, PLCG1, TOMM34, NCOA5, ZNFX1, YTHDF1, GMEB2, TPD52L2, BACH1, URB1, PAXBP1, DONSON, SETD4, CBR1, DYRK1A, NDUFV3, PDXK, SUMO3, DIP2A, BID, USP18, CLTCL1, HIRA, CRKL, SRRD, TFIP11, PITPNB, NIPSNAP1, NF2, SF3A1, PES1, OSBP2, APOL6, PDXP, TAB1, ATF4, TNRC6B, ADSL, SGSM3, MKL1, SLC25A17, ZC3H7B, DESI1, XRCC6, POLDIP3, CYB5R3, PACSIN2, LDOC1L, TUBGCP6, HDHD1, PIR, CA5B, TXLNG, SH3KBP1, PRDX4, POLA1, ATP6AP2, RBM10, USP11, EBP, HDAC6, KDM5C, SPIN4, OPHN1, KIF4A, ZMYM3, TAF1, OGT, MAGT1, TCEAL8, MORC4, TMEM164, NKRF, OCRL, AIFM1, ENOX2, FIRRE, MBNL3, HMGB3, NSDHL, BCAP31, IRAK1, EMD, TAZ, ATP6AP1, FAM50A, UBL4A, DKC1, FUNDC2, OBSL1, SUZ12, EED, BMI1, LUZP4, HNRNPA1, BAG1, GTPBP1, APEX1, CUL4B, LASP1, SPTBN1, KRAS, IFI16, NUP153, SRPK2, RPL10, UBE2I, NUP107, SEH1L, MEX3C, NXT2, GPR37, GLE1, MKRN2, RGPD5, C17orf85, YARS2, NCL


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for EEF1G_NXF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for EEF1G_NXF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource