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Center for Computational Systems Medicine
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FusionGeneSummary

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Fusion gene ID: 10587

FusionGeneSummary for DSG1_TNXB

check button Fusion gene summary
Fusion gene informationFusion gene name: DSG1_TNXB
Fusion gene ID: 10587
HgeneTgene
Gene symbol

DSG1

TNXB

Gene ID

1828

7148

Gene namedesmoglein 1tenascin XB
SynonymsCDHF4|DG1|DSG|EPKHE|EPKHIA|PPKS1|SPPK1EDS3|EDSCLL|HXBL|TENX|TN-X|TNX|TNXB1|TNXB2|TNXBS|VUR8|XB|XBS
Cytomap

18q12.1

6p21.33-p21.32

Type of geneprotein-codingprotein-coding
Descriptiondesmoglein-1cadherin family member 4desmosomal glycoprotein 1pemphigus foliaceus antigentenascin-Xgrowth-inhibiting protein 45hexabrachion-like proteintenascin XB1tenascin XB2
Modification date2018052720180522
UniProtAcc

Q02413

P22105

Ensembl transtripts involved in fusion geneENST00000257192, ENST00000462981, 
ENST00000375244, ENST00000451343, 
ENST00000375247, ENST00000479795, 
ENST00000433037, ENST00000549232, 
ENST00000383159, ENST00000489006, 
ENST00000469250, ENST00000440248, 
ENST00000550212, ENST00000548649, 
ENST00000424718, ENST00000475986, 
ENST00000550539, ENST00000471059, 
ENST00000551808, ENST00000548628, 
ENST00000549652, ENST00000553092, 
ENST00000552665, ENST00000465958, 
ENST00000546684, ENST00000464376, 
ENST00000552149, ENST00000551201, 
Fusion gene scores* DoF score2 X 2 X 2=86 X 6 X 5=180
# samples 26
** MAII scorelog2(2/8*10)=1.32192809488736log2(6/180*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DSG1 [Title/Abstract] AND TNXB [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDSG1

GO:0050821

protein stabilization

7983064


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDSTADTCGA-VQ-A922-01ADSG1chr18

28919988

+TNXBchr6

32038191

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000257192ENST00000375244DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000451343DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000375247DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000479795DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000433037DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000549232DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000383159DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000489006DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000469250DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000440248DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000550212DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000548649DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000424718DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000475986DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000550539DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000471059DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000551808DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000548628DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000549652DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000553092DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000552665DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000465958DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000546684DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000464376DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000552149DSG1chr18

28919988

+TNXBchr6

32038191

-
5CDS-intronENST00000257192ENST00000551201DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-3CDSENST00000462981ENST00000375244DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000451343DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000375247DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000479795DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000433037DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000549232DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000383159DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000489006DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000469250DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000440248DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000550212DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000548649DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000424718DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000475986DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000550539DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000471059DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000551808DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000548628DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000549652DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000553092DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000552665DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000465958DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000546684DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000464376DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000552149DSG1chr18

28919988

+TNXBchr6

32038191

-
intron-intronENST00000462981ENST00000551201DSG1chr18

28919988

+TNXBchr6

32038191

-

Top

FusionProtFeatures for DSG1_TNXB


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DSG1

Q02413

TNXB

P22105

Component of intercellular desmosome junctions. Involvedin the interaction of plaque proteins and intermediate filamentsmediating cell-cell adhesion.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+1115159_2705621050DomainCadherin 2
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+1115271_3855621050DomainCadherin 3
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+1115386_4975621050DomainCadherin 4
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+111550_1585621050DomainCadherin 1
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+111550_5485621050Topological domainExtracellular
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12441674_176416634243DomainFibronectin type-III 8
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12441778_186816634243DomainFibronectin type-III 9
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12441883_197116634243DomainFibronectin type-III 10
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12441989_208916634243DomainFibronectin type-III 11
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12442097_218516634243DomainFibronectin type-III 12
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12442196_229616634243DomainFibronectin type-III 13
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12442305_239816634243DomainFibronectin type-III 14
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12442408_250216634243DomainFibronectin type-III 15
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12442519_261716634243DomainFibronectin type-III 16
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12442625_272316634243DomainFibronectin type-III 17
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12442733_283816634243DomainFibronectin type-III 18
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12442839_293716634243DomainFibronectin type-III 19
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12442947_304016634243DomainFibronectin type-III 20
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12443060_315116634243DomainFibronectin type-III 21
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12443166_325816634243DomainFibronectin type-III 22
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12443262_335316634243DomainFibronectin type-III 23
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12443355_344416634243DomainFibronectin type-III 24
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12443449_354216634243DomainFibronectin type-III 25
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12443551_364516634243DomainFibronectin type-III 26
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12443655_375216634243DomainFibronectin type-III 27
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12443756_384516634243DomainFibronectin type-III 28
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12443846_393216634243DomainFibronectin type-III 29
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12443933_402316634243DomainFibronectin type-III 30
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12444019_423416634243DomainFibrinogen C-terminal
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0131064_1153-303674DomainFibronectin type-III 2
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0131161_1249-303674DomainFibronectin type-III 3
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0131263_1352-303674DomainFibronectin type-III 4
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0131374_1468-303674DomainFibronectin type-III 5
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0131476_1572-303674DomainFibronectin type-III 6
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013156_168-303674DomainEGF-like 1%3B incomplete
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0131574_1669-303674DomainFibronectin type-III 7
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0131674_1764-303674DomainFibronectin type-III 8
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0131778_1868-303674DomainFibronectin type-III 9
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013183_213-303674DomainEGF-like 2
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0131883_1971-303674DomainFibronectin type-III 10
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0131989_2089-303674DomainFibronectin type-III 11
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0132097_2185-303674DomainFibronectin type-III 12
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013214_244-303674DomainEGF-like 3
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0132196_2296-303674DomainFibronectin type-III 13
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0132305_2398-303674DomainFibronectin type-III 14
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0132408_2502-303674DomainFibronectin type-III 15
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013245_275-303674DomainEGF-like 4
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0132519_2617-303674DomainFibronectin type-III 16
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0132625_2723-303674DomainFibronectin type-III 17
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0132733_2838-303674DomainFibronectin type-III 18
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013276_306-303674DomainEGF-like 5
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0132839_2937-303674DomainFibronectin type-III 19
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0132947_3040-303674DomainFibronectin type-III 20
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0133060_3151-303674DomainFibronectin type-III 21
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013307_337-303674DomainEGF-like 6
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0133166_3258-303674DomainFibronectin type-III 22
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0133262_3353-303674DomainFibronectin type-III 23
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0133355_3444-303674DomainFibronectin type-III 24
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013338_368-303674DomainEGF-like 7
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0133449_3542-303674DomainFibronectin type-III 25
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0133551_3645-303674DomainFibronectin type-III 26
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0133655_3752-303674DomainFibronectin type-III 27
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013369_399-303674DomainEGF-like 8
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0133756_3845-303674DomainFibronectin type-III 28
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0133846_3932-303674DomainFibronectin type-III 29
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0133933_4023-303674DomainFibronectin type-III 30
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013400_430-303674DomainEGF-like 9
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0134019_4234-303674DomainFibrinogen C-terminal
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013431_461-303674DomainEGF-like 10
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013462_492-303674DomainEGF-like 11
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013493_523-303674DomainEGF-like 12
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013524_554-303674DomainEGF-like 13
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013555_585-303674DomainEGF-like 14
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013586_616-303674DomainEGF-like 15
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013617_647-303674DomainEGF-like 16
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013648_679-303674DomainEGF-like 17
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013684_714-303674DomainEGF-like 18
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013715_746-303674DomainEGF-like 19
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-013959_1051-303674DomainFibronectin type-III 1
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0151064_1153-212674DomainFibronectin type-III 2
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0151161_1249-212674DomainFibronectin type-III 3
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0151263_1352-212674DomainFibronectin type-III 4
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0151374_1468-212674DomainFibronectin type-III 5
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0151476_1572-212674DomainFibronectin type-III 6
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015156_168-212674DomainEGF-like 1%3B incomplete
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0151574_1669-212674DomainFibronectin type-III 7
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0151674_1764-212674DomainFibronectin type-III 8
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0151778_1868-212674DomainFibronectin type-III 9
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015183_213-212674DomainEGF-like 2
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0151883_1971-212674DomainFibronectin type-III 10
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0151989_2089-212674DomainFibronectin type-III 11
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0152097_2185-212674DomainFibronectin type-III 12
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015214_244-212674DomainEGF-like 3
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0152196_2296-212674DomainFibronectin type-III 13
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0152305_2398-212674DomainFibronectin type-III 14
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0152408_2502-212674DomainFibronectin type-III 15
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015245_275-212674DomainEGF-like 4
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0152519_2617-212674DomainFibronectin type-III 16
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0152625_2723-212674DomainFibronectin type-III 17
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0152733_2838-212674DomainFibronectin type-III 18
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015276_306-212674DomainEGF-like 5
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0152839_2937-212674DomainFibronectin type-III 19
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0152947_3040-212674DomainFibronectin type-III 20
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0153060_3151-212674DomainFibronectin type-III 21
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015307_337-212674DomainEGF-like 6
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0153166_3258-212674DomainFibronectin type-III 22
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0153262_3353-212674DomainFibronectin type-III 23
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0153355_3444-212674DomainFibronectin type-III 24
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015338_368-212674DomainEGF-like 7
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0153449_3542-212674DomainFibronectin type-III 25
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0153551_3645-212674DomainFibronectin type-III 26
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0153655_3752-212674DomainFibronectin type-III 27
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015369_399-212674DomainEGF-like 8
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0153756_3845-212674DomainFibronectin type-III 28
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0153846_3932-212674DomainFibronectin type-III 29
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0153933_4023-212674DomainFibronectin type-III 30
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015400_430-212674DomainEGF-like 9
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0154019_4234-212674DomainFibrinogen C-terminal
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015431_461-212674DomainEGF-like 10
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015462_492-212674DomainEGF-like 11
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015493_523-212674DomainEGF-like 12
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015524_554-212674DomainEGF-like 13
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015555_585-212674DomainEGF-like 14
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015586_616-212674DomainEGF-like 15
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015617_647-212674DomainEGF-like 16
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015648_679-212674DomainEGF-like 17
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015684_714-212674DomainEGF-like 18
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015715_746-212674DomainEGF-like 19
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-015959_1051-212674DomainFibronectin type-III 1
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0151064_1153-212674DomainFibronectin type-III 2
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0151161_1249-212674DomainFibronectin type-III 3
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0151263_1352-212674DomainFibronectin type-III 4
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0151374_1468-212674DomainFibronectin type-III 5
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0151476_1572-212674DomainFibronectin type-III 6
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015156_168-212674DomainEGF-like 1%3B incomplete
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0151574_1669-212674DomainFibronectin type-III 7
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0151674_1764-212674DomainFibronectin type-III 8
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0151778_1868-212674DomainFibronectin type-III 9
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015183_213-212674DomainEGF-like 2
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0151883_1971-212674DomainFibronectin type-III 10
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0151989_2089-212674DomainFibronectin type-III 11
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0152097_2185-212674DomainFibronectin type-III 12
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015214_244-212674DomainEGF-like 3
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0152196_2296-212674DomainFibronectin type-III 13
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0152305_2398-212674DomainFibronectin type-III 14
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0152408_2502-212674DomainFibronectin type-III 15
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015245_275-212674DomainEGF-like 4
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0152519_2617-212674DomainFibronectin type-III 16
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0152625_2723-212674DomainFibronectin type-III 17
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0152733_2838-212674DomainFibronectin type-III 18
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015276_306-212674DomainEGF-like 5
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0152839_2937-212674DomainFibronectin type-III 19
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0152947_3040-212674DomainFibronectin type-III 20
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0153060_3151-212674DomainFibronectin type-III 21
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015307_337-212674DomainEGF-like 6
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0153166_3258-212674DomainFibronectin type-III 22
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0153262_3353-212674DomainFibronectin type-III 23
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0153355_3444-212674DomainFibronectin type-III 24
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015338_368-212674DomainEGF-like 7
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0153449_3542-212674DomainFibronectin type-III 25
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0153551_3645-212674DomainFibronectin type-III 26
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0153655_3752-212674DomainFibronectin type-III 27
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015369_399-212674DomainEGF-like 8
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0153756_3845-212674DomainFibronectin type-III 28
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0153846_3932-212674DomainFibronectin type-III 29
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0153933_4023-212674DomainFibronectin type-III 30
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015400_430-212674DomainEGF-like 9
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0154019_4234-212674DomainFibrinogen C-terminal
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015431_461-212674DomainEGF-like 10
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015462_492-212674DomainEGF-like 11
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015493_523-212674DomainEGF-like 12
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015524_554-212674DomainEGF-like 13
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015555_585-212674DomainEGF-like 14
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015586_616-212674DomainEGF-like 15
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015617_647-212674DomainEGF-like 16
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015648_679-212674DomainEGF-like 17
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015684_714-212674DomainEGF-like 18
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015715_746-212674DomainEGF-like 19
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-015959_1051-212674DomainFibronectin type-III 1
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12441666_166816634243MotifCell attachment site
TgeneTNXBchr18:28919988chr6:32038191ENST00000451343-0131666_1668-303674MotifCell attachment site
TgeneTNXBchr18:28919988chr6:32038191ENST00000546684-0151666_1668-212674MotifCell attachment site
TgeneTNXBchr18:28919988chr6:32038191ENST00000550539-0151666_1668-212674MotifCell attachment site

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+1115969_10195621050Compositional biasNote=Gly/Ser-rich
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+1115813_8395621050RepeatNote=Desmoglein repeat 1
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+1115840_8695621050RepeatNote=Desmoglein repeat 2
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+1115870_8995621050RepeatNote=Desmoglein repeat 3
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+1115900_9275621050RepeatNote=Desmoglein repeat 4
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+1115928_9565621050RepeatNote=Desmoglein repeat 5
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+1115570_10495621050Topological domainCytoplasmic
HgeneDSG1chr18:28919988chr6:32038191ENST00000257192+1115549_5695621050TransmembraneHelical
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12441064_115316634243DomainFibronectin type-III 2
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12441161_124916634243DomainFibronectin type-III 3
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12441263_135216634243DomainFibronectin type-III 4
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12441374_146816634243DomainFibronectin type-III 5
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12441476_157216634243DomainFibronectin type-III 6
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244156_16816634243DomainEGF-like 1%3B incomplete
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-12441574_166916634243DomainFibronectin type-III 7
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244183_21316634243DomainEGF-like 2
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244214_24416634243DomainEGF-like 3
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244245_27516634243DomainEGF-like 4
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244276_30616634243DomainEGF-like 5
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244307_33716634243DomainEGF-like 6
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244338_36816634243DomainEGF-like 7
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244369_39916634243DomainEGF-like 8
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244400_43016634243DomainEGF-like 9
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244431_46116634243DomainEGF-like 10
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244462_49216634243DomainEGF-like 11
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244493_52316634243DomainEGF-like 12
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244524_55416634243DomainEGF-like 13
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244555_58516634243DomainEGF-like 14
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244586_61616634243DomainEGF-like 15
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244617_64716634243DomainEGF-like 16
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244648_67916634243DomainEGF-like 17
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244684_71416634243DomainEGF-like 18
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244715_74616634243DomainEGF-like 19
TgeneTNXBchr18:28919988chr6:32038191ENST00000375247-1244959_105116634243DomainFibronectin type-III 1


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FusionGeneSequence for DSG1_TNXB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_DSG1_ENST00000257192_chr18_28919988_+_TNXB_ENST00000375244_chr6_32038191_-_3144aa
MDWSFFRVVAMLFIFLVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGV
GIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILN
ATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYME
QSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHS
IMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTK
EQYNMLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLL
SDNVHFGPAGIGLLIMGFLVLGFARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPL
DAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVP
VEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSF
EIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPD
SLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPE
PAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVT
APEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRV
GPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGL
EPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGR
PQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLS
WTVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRL
GELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETP
SPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGR
RVGPVSTVGVTAPEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHEDGVTISG
LEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDG
RPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWM
VPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGE
LTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPV
EPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPD
TKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTT
APLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSA
LGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYR
FLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMV
PGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSV
QVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAET
PGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPG
GITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLV
FQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_DSG1_ENST00000257192_chr18_28919988_+_TNXB_ENST00000375244_chr6_32038191_-_9432nt
ATGGACTGGAGTTTCTTCAGAGTAGTTGCAATGCTGTTCATTTTTCTGGTGGTGGTAGAAGTTAACAGTGAATTCCGAATCCAGGTAAGA
GATTATAACACTAAAAATGGCACCATCAAATGGCATTCAATCCGAAGGCAGAAACGTGAATGGATCAAGTTCGCAGCAGCCTGTCGTGAA
GGTGAAGACAACTCAAAGAGGAACCCAATCGCCAAAATTCACTCAGATTGTGCTGCAAACCAGCAAGTTACATACCGCATCTCTGGAGTA
GGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAACATCCATAGTTGATCGAGAGGTCACT
CCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTCAGAGTCAGGGTTTTGGATATA
AATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAATACACTGGTGATGATACTCAAT
GCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCTTCAGATTCACCAATGTTTATT
ATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCCAGTATGCTCTTGCTGTAAGAGGCTCT
GACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAATGATAATATCCCTTACATGGAA
CAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATTGATTTGGATGAAGAGTTCTCA
GCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAATGAAAGAACAAATGTGGGAATT
TTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAATAAAGCTGAATTTCATCATTCA
ATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCAGTGTTTCGTCCAGGTTCAAAG
ACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGACACAGGTAGACCTTCAACGACT
GTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACTTTGAAAAATAAAGTTACCAAG
GAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTCAAAGAACTTGCACTGGTACAATTAAT
ATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAATACTGGCAGACAAGAAAGTACT
TCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGAAACGGAGCCAAAGATTTGTTA
TCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTTGCCCGAGGTGACGCCAGCCCA
GGGGCCCCACCCCGCCTTGGGGAGCTGTGGGTGACAGACCCCACCCCAGACTCACTGCGCCTCTCCTGGACGGTTCCTGAGGGCCAGTTC
GACTCTTTTGTGGTCCAGTTCAAGGACAAAGACGGGCCCCAGGTGGTGCCCGTGGAGGGCCATGAGCGCTCTGTCACTGTCACCCCTCTG
GATGCCGGCCGCAAGTACAGATTCCTCCTCTATGGCCTCCTGGGCAAGAAGCGCCATGGCCCTCTCACTGCCGACGGCACCACGGAAGCC
CGGAGTGCTATGGATGATACTGGAACAAAGCGTCCCCCAAAACCCCGTCTGGGGGAGGAGCTGCAGGTGACCACCGTGACCCAGAACTCC
GTGGGCCTCTCCTGGACAGTCCCTGAGGGCCAGTTTGACTCCTTTGTGGTCCAGTACAAAGACAGGGACGGGCAGCCCCAGGTGGTGCCC
GTGGAGGGCAGCCTCAGGGAGGTCAGCGTGCCGGGCCTGGACCCTGCCCACAGGTACAAGCTGCTGCTCTACGGGCTGCACCACGGCAAG
CGTGTGGGCCCCATCTCGGCCGTCGCCATTACTGCCGGCAGGGAAGAAACGGAAACTGAGACCACGGCCCCGACCCCTCCAGCGCCTGAG
CCCCACCTCGGGGAGTTGACAGTGGAGGAGGCCACGTCACACACCCTGCATCTCTCCTGGATGGTGACTGAGGGAGAATTTGACTCCTTC
GAAATCCAGTACACAGATAGAGACGGGCAACTCCAAATGGTCCGCATAGGAGGTGACCGGAATGACATCACCCTCTCTGGCCTGGAATCC
GACCACAGATACCTGGTGACCCTGTATGGTTTCAGTGATGGGAAGCATGTAGGTCCTGTCCATGTCGAGGCCCTGACAGTCCCGGAGGAG
GAGAAGCCTTCAGAACCTCCCACCGCAACCCCCGAGCCCCCCATCAAGCCTCGCCTGGGGGAGCTGACCGTGACAGATGCCACCCCTGAC
TCCCTCAGCCTGTCCTGGACAGTTCCCGAGGGACAGTTTGACCACTTCCTGGTCCAGTACAGGAATGGAGATGGGCAGCCCAAGGCAGTG
AGGGTGCCAGGGCACGAGGAAGGGGTCACCATCTCGGGCCTGGAGCCAGACCATAAATACAAGATGAACCTGTACGGCTTCCACGGTGGC
CAGCGCATGGGCCCTGTGTCTGTCGTCGGGGTGACAGCTGCAGAGGAAGAGACCCCCAGCCCCACAGAACCCAGCATGGAGGCCCCGGAG
CCCGCTGAGGAGCCGCTCCTGGGGGAGCTAACAGTGACAGGATCCTCCCCTGACTCGCTGAGCCTCTCCTGGACCGTCCCCCAGGGCCGC
TTCGACTCCTTCACCGTGCAGTACAAGGACAGGGACGGGCGGCCCCAGGTGGTGCGTGTTGGGGGCGAGGAGAGTGAAGTCACCGTGGGG
GGCCTGGAGCCTGGGCGCAAGTACAAGATGCACCTGTACGGCCTCCACGAGGGGCGGCGCGTGGGCCCAGTGTCTGCTGTGGGCGTCACG
GCCCCCGAAGAGGAGTCCCCTGATGCTCCTCTTGCAAAGCTGCGCCTAGGGCAGATGACAGTGAGAGACATCACCTCCGACTCCCTCAGC
CTCTCCTGGACAGTCCCCGAGGGCCAGTTTGACCATTTCTTGGTCCAGTTTAAGAATGGGGACGGGCAGCCCAAGGCGGTGCGGGTGCCG
GGACACGAGGATGGGGTCACCATCTCGGGCCTGGAGCCAGACCACAAGTACAAGATGAACCTGTACGGCTTCCACGGTGGCCAGCGCGTG
GGCCCCGTGTCTGCTGTTGGTTTAACTGCCCCAGGAAAGGATGAAGAAATGGCCCCAGCCTCGACAGAACCTCCCACCCCTGAACCCCCC
ATCAAGCCTCGCCTGGAGGAGCTGACCGTGACAGATGCGACCCCTGACTCCCTCAGCCTGTCCTGGACGGTTCCCGAGGGACAGTTTGAC
CACTTCCTGGTCCAGTACAAGAATGGGGATGGGCAGCCCAAGGCAACACGGGTGCCAGGACATGAGGACAGGGTCACCATCTCCGGCCTG
GAGCCAGACAACAAGTACAAGATGAACCTGTACGGCTTCCACGGTGGCCAGCGTGTGGGCCCCGTGTCTGCCATCGGGGTGACAGCTGCA
GAGGAAGAGACCCCCAGCCCCACAGAACCCAGCATGGAGGCCCCGGAGCCCCCTGAGGAGCCGCTCCTGGGGGAGCTAACAGTGACAGGA
TCCTCCCCTGACTCGCTGAGCCTCTCCTGGACCGTCCCCCAGGGCCGCTTCGACTCCTTCACCGTGCAGTACAAGGACAGGGACGGGCGG
CCCCAGGTGGTGCGTGTTGGGGGCGAGGAGAGCGAGGTCACCGTGGGGGGCCTGGAGCCTGGGCGCAAATACAAGATGCACCTGTATGGC
CTCCACGAGGGGCGGCGCGTGGGCCCGGTGTCCACCGTGGGCGTGACTGCCCCACAAGAGGATGTGGACGAGACCCCCAGCCCTACAGAA
CCAGGCACAGAGGCCCCAGGGCCCCCCGAGGAGCCTCTCCTGGGGGAGCTGACAGTGACAGGATCCTCCCCTGACTCGCTGAGCCTTTCC
TGGACCGTCCCCCAGGGCCGCTTTGACTCCTTCACCGTGCAGTACAAGGACAGGGACGGGCGGCCCCAGGCGGTGCGTGTTGGGGGCCAG
GAGAGCAAGGTCACTGTGAGGGGCCTGGAGCCTGGGCGCAAGTACAAGATGCACCTGTACGGCCTCCACGAGGGGCGGCGCCTGGGCCCG
GTGTCTGCCGTGGGCGTCACAGAGGATGAAGCCGAGACCACCCAAGCAGTGCCTACCATGACCCCTGAGCCCCCCATCAAGCCTCGCCTG
GGGGAGCTGACCATGACAGATGCCACCCCTGACTCCCTCAGCCTGTCCTGGACGGTTCCCGAGGGCCAGTTTGACCACTTCCTGGTCCAG
TACAGGAATGGGGATGGGCAGCCCAAGGCGGTGCGGGTGCCGGGGCACGAGGACGGGGTCACCATCTCAGGCCTGGAGCCAGACCATAAA
TACAAGATGAACCTGTACGGCTTCCACGGTGGCCAGCGCGTGGGCCCCATCTCTGTCATTGGGGTGACGGCTGCAGAGGAAGAGACCCCC
AGCCCCACGGAACTCAGCACTGAGGCCCCGGAGCCCCCTGAGGAGCCGCTCCTGGGGGAGCTGACAGTGACAGGATCCTCCCCTGACTCG
CTGAGCCTCTCCTGGACCATCCCCCAGGGCCACTTCGACTCCTTCACCGTGCAGTACAAGGACAGGGACGGGCGGCCCCAGGTGATGCGT
GTCAGGGGCGAGGAGAGCGAGGTCACCGTGGGGGGCCTGGAGCCCGGGCGCAAATACAAGATGCACCTGTACGGCCTCCACGAGGGGCGG
CGTGTGGGCCCGGTGTCCACCGTGGGTGTGACAGCTCCAGAGGATGAAGCAGAGACCACCCAAGCAGTGCCCACCACAACCCCTGAGCCC
CCCAACAAGCCTCGCCTCGGGGAGCTGACCGTGACAGATGCCACCCCTGACTCCCTCAGCCTGTCCTGGATGGTCCCCGAGGGCCAGTTT
GACCACTTCCTGGTCCAGTACAGGAATGGGGATGGGCAGCCCAAGGTGGTGCGGGTGCCGGGGCACGAGGACGGGGTCACCATCTCAGGC
CTGGAGCCAGACCACAAGTACAAGATGAACCTGTACGGCTTCCACGGTGGCCAGCGCGTGGGCCCCATCTCTGTCATTGGGGTGACAGCT
GCAGAGGAAGAAACTCCCGCCCCCACAGAACCCAGCACGGAGGCCCCGGAGCCCCCTGAGGAGCCGCTCCTGGGGGAGCTGACAGTGACA
GGATCCTCCCCTGACTCGCTGAGCCTCTCCTGGACCATCCCCCAGGGCCGCTTCGACTCCTTCACTGTGCAGTACAAGGACAGGGACGGG
CGGCCCCAGGTGGTGCGTGTCAGGGGCGAGGAGAGCGAGGTCACCGTGGGGGGCCTGGAGCCCGGGTGCAAATACAAGATGCACCTGTAC
GGCCTCCACGAGGGGCAGCGCGTGGGCCCAGTGTCCGCTGTGGGTGTGACAGCTCCAAAGGATGAAGCCGAGACCACCCAAGCAGTGCCT
ACCATGACCCCTGAGCCCCCCATCAAGCCTCGCCTGGGGGAGCTGACCGTGACAGATGCCACCCCCGACTCCCTCAGCCTGTCCTGGATG
GTTCCCGAGGGCCAGTTTGACCACTTCCTGGTCCAGTACAGGAATGGGGATGGGCAGCCCAAGGCGGTGCGGGTGCCGGGGCACGAGGAC
GGGGTCACCATCTCAGGCCTGGAGCCAGACCATAAATACAAGATGAACCTGTACGGCTTCCACGGTGGCCAGCGCGTAGGCCCTGTGTCT
GCCATTGGGGTGACGGAGGAAGAGACCCCCAGCCCCACAGAACCCAGCACTGAGGCCCCGGAGGCCCCTGAGGAGCCGCTCCTGGGGGAG
TTGACAGTGACAGGATCCTCCCCTGACTCGCTGAGCCTCTCCTGGACCGTCCCCCAGGGCCGCTTCGACTCCTTCACCGTGCAGTACAAG
GACAGGGACGGGCAGCCCCAGGTGGTGCGTGTCAGGGGCGAGGAGAGCGAGGTCACCGTGGGGGGCCTGGAGCCCGGGCGCAAATACAAG
ATGCATCTGTACGGCCTCCACGAGGGGCAGCGCGTGGGCCCAGTGTCCACCGTGGGCATCACGGCGCCCCTGCCCACACCACTGCCGGTG
GAGCCCCGCCTGGGGGAGCTGGCGGTGGCGGCCGTGACCTCGGACTCAGTGGGCCTCTCATGGACGGTGGCCCAGGGCCCCTTTGACTCC
TTCCTGGTACAGTACAGGGACGCGCAGGGGCAGCCCCAGGCAGTGCCTGTGAGCGGAGACCTCCGAGCGGTCGCCGTCTCGGGGCTGGAC
CCGGCCCGCAAGTACAAGTTCCTGCTCTTTGGACTCCAGAATGGGAAACGCCACGGCCCAGTCCCTGTGGAGGCCAGGACCGCCCCAGAC
ACCAAACCGTCTCCCCGCCTGGGGGAGCTGACTGTGACAGATGCGACCCCTGACTCCGTGGGCCTCTCGTGGACGGTCCCTGAGGGCGAA
TTCGACTCCTTCGTGGTCCAGTACAAGGATAAGGATGGTCGGCTCCAGGTGGTGCCGGTGGCAGCCAACCAGCGGGAGGTCACAGTCCAG
GGCCTGGAGCCCAGTAGGAAATACAGGTTCCTGCTCTATGGTCTGTCAGGCAGGAAACGACTGGGCCCCATCTCTGCTGACAGCACCACA
GCTCCCCTGGAGAAGGAGCTACCTCCCCACCTGGGGGAACTGACCGTGGCTGAGGAGACCTCCAGCTCTCTGCGCCTGTCCTGGACGGTA
GCCCAGGGCCCCTTTGACTCCTTCGTGGTCCAGTACAGGGACACGGACGGGCAGCCCAGGGCAGTGCCTGTGGCCGCAGACCAGCGCACA
GTCACCGTAGAGGACCTGGAGCCTGGCAAGAAATACAAGTTTCTGCTCTACGGGCTCCTTGGGGGAAAGCGCCTGGGCCCGGTCTCTGCC
CTGGGAATGACAGCCCCAGAAGAGGACACACCAGCCCCAGAGTTAGCCCCAGAGGCCCCTGAGCCTCCTGAAGAGCCCCGCCTAGGAGTG
CTGACCGTGACCGACACAACCCCAGACTCCATGCGCCTCTCGTGGAGCGTGGCCCAGGGCCCCTTTGATTCCTTCGTGGTCCAGTATGAG
GACACGAACGGGCAGCCCCAGGCCTTGCTCGTGGACGGCGACCAGAGCAAGATCCTCATCTCAGGCCTGGAGCCCAGCACCCCCTACAGG
TTCCTCCTCTATGGCCTCCATGAAGGGAAGCGCCTGGGGCCCCTCTCAGCTGAGGGCACCACAGGGCTGGCTCCTGCTGGTCAGACCTCA
GAGGAGTCAAGGCCCCGCCTGTCCCAGCTGTCTGTGACTGACGTGACCACCAGTTCACTGAGGCTCAACTGGGAGGCCCCACCGGGGGCC
TTCGACTCCTTCCTGCTCCGCTTTGGGGTTCCATCACCAAGCACTCTGGAGCCGCATCCGCGTCCACTGCTGCAGCGCGAGCTGATGGTG
CCGGGGACGCGGCACTCGGCCGTGCTCCGGGACCTGCGTTCCGGGACTCTGTACAGCCTGACACTGTATGGGCTGCGAGGACCCCACAAG
GCCGACAGCATCCAGGGAACCGCCCGCACCCTCAGCCCAGTTCTGGAGAGCCCCCGTGACCTCCAATTCAGTGAAATCAGGGAGACCTCA
GCCAAGGTCAACTGGATGCCCCCACCATCCCGGGCGGACAGCTTCAAAGTCTCCTACCAGCTGGCGGACGGAGGGGAGCCTCAGAGTGTG
CAGGTGGATGGCCAGGCCCGGACCCAGAAACTCCAGGGGCTGATCCCAGGCGCTCGCTATGAGGTGACCGTGGTCTCGGTCCGAGGCTTT
GAGGAGAGTGAGCCTCTCACAGGCTTCCTCACCACGGTTCCTGACGGTCCCACACAGTTGCGTGCACTGAACTTGACCGAGGGATTCGCC
GTGCTGCACTGGAAGCCCCCCCAGAATCCTGTGGACACCTATGACGTCCAGGTCACAGCCCCTGGGGCCCCGCCTCTGCAGGCGGAGACC
CCAGGCAGCGCGGTGGACTACCCCCTGCATGACCTTGTCCTCCACACCAACTACACCGCCACAGTGCGTGGCCTGCGGGGCCCCAACCTC
ACTTCCCCAGCCAGCATCACCTTCACCACAGGGCTAGAGGCCCCTCGGGACTTGGAGGCCAAGGAAGTGACCCCCCGCACCGCCCTGCTC
ACTTGGACTGAGCCCCCAGTCCGGCCCGCAGGCTACCTGCTCAGCTTCCACACCCCTGGTGGACAGAACCAGGAGATCCTGCTCCCAGGA
GGGATCACATCTCACCAGCTCCTTGGCCTCTTTCCCTCCACCTCCTACAATGCACGGCTCCAGGCCATGTGGGGCCAGAGCCTCCTGCCG
CCCGTGTCCACCTCTTTCACCACGGGTGGGCTGCGGATCCCCTTCCCCAGGGACTGCGGGGAGGAGATGCAGAACGGAGCCGGTGCCTCC
AGGACCAGCACCATCTTCCTCAACGGCAACCGCGAGCGGCCCCTGAACGTGTTTTGCGACATGGAGACTGATGGGGGCGGCTGGCTGGTG
TTCCAGCGCCGCATGGATGGACAGACAGACTTCTGGAGGGACTGGGAGGACTATGCCCATGGTTTTGGGAACATCTCTGGAGAGTTCTGG
CTGGGCAATGAGGCCCTGCACAGCCTGACACAGGCAGGTGACTACTCCATGCGCGTGGACCTGCGGGCTGGGGACGAGGCTGTGTTCGCC
CAGTACGACTCCTTCCACGTAGACTCGGCTGCGGAGTACTACCGCCTCCACTTGGAGGGCTACCACGGCACCGCAGGGGACTCCATGAGC
TACCACAGCGGCAGTGTCTTCTCTGCCCGTGATCGGGACCCCAACAGCTTGCTCATCTCCTGCGCTGTCTCCTACCGAGGGGCCTGGTGG
TACAGGAACTGCCACTACGCCAACCTCAACGGGCTCTACGGGAGCACAGTGGACCATCAGGGAGTGAGCTGGTACCACTGGAAGGGCTTC


* Fusion transcript sequences (Full-length transcript).
>In-frame_DSG1_ENST00000257192_chr18_28919988_+_TNXB_ENST00000375244_chr6_32038191_-_9839nt
CCAGCCCAAGTTTTTAGGGTGGGGATCCAGACTGGTTATACGTACCTTCAGTCCTTCTCCCAGAGGAAGGCAGAAACACCTCAAAGCCTG
CATGTAAGAACATCTACTGAGAAATTATTTTAATCAGACACCAGCTGAGTGGGAGAAAGAAAAAGAACAGAGAAGAACAAACAAAACTCC
CTTGGTCTTGGATGTAAGAGAATCCAGCAGAGATGGACTGGAGTTTCTTCAGAGTAGTTGCAATGCTGTTCATTTTTCTGGTGGTGGTAG
AAGTTAACAGTGAATTCCGAATCCAGGTAAGAGATTATAACACTAAAAATGGCACCATCAAATGGCATTCAATCCGAAGGCAGAAACGTG
AATGGATCAAGTTCGCAGCAGCCTGTCGTGAAGGTGAAGACAACTCAAAGAGGAACCCAATCGCCAAAATTCACTCAGATTGTGCTGCAA
ACCAGCAAGTTACATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTA
ATATAACATCCATAGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGC
CTCTAGAGCTCAGAGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATT
CTAATGCAAATACACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAA
GACAAGAACCTTCAGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAAT
ACGGCCAGTATGCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCC
TCGATGTCAATGATAATATCCCTTACATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGA
TTAGAGTAATTGATTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGA
TAGAAATGAATGAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTG
GTGTCAGAAATAAAGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAA
TTGAAGGCCCAGTGTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTA
CTGACCTGGACACAGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAG
GCAAACTCACTTTGAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATA
ATCTTCAAAGAACTTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAA
TTACTACCAATACTGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTT
CTGAACCCGGAAACGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGG
TCTTAGGATTTGCCCGAGGTGACGCCAGCCCAGGGGCCCCACCCCGCCTTGGGGAGCTGTGGGTGACAGACCCCACCCCAGACTCACTGC
GCCTCTCCTGGACGGTTCCTGAGGGCCAGTTCGACTCTTTTGTGGTCCAGTTCAAGGACAAAGACGGGCCCCAGGTGGTGCCCGTGGAGG
GCCATGAGCGCTCTGTCACTGTCACCCCTCTGGATGCCGGCCGCAAGTACAGATTCCTCCTCTATGGCCTCCTGGGCAAGAAGCGCCATG
GCCCTCTCACTGCCGACGGCACCACGGAAGCCCGGAGTGCTATGGATGATACTGGAACAAAGCGTCCCCCAAAACCCCGTCTGGGGGAGG
AGCTGCAGGTGACCACCGTGACCCAGAACTCCGTGGGCCTCTCCTGGACAGTCCCTGAGGGCCAGTTTGACTCCTTTGTGGTCCAGTACA
AAGACAGGGACGGGCAGCCCCAGGTGGTGCCCGTGGAGGGCAGCCTCAGGGAGGTCAGCGTGCCGGGCCTGGACCCTGCCCACAGGTACA
AGCTGCTGCTCTACGGGCTGCACCACGGCAAGCGTGTGGGCCCCATCTCGGCCGTCGCCATTACTGCCGGCAGGGAAGAAACGGAAACTG
AGACCACGGCCCCGACCCCTCCAGCGCCTGAGCCCCACCTCGGGGAGTTGACAGTGGAGGAGGCCACGTCACACACCCTGCATCTCTCCT
GGATGGTGACTGAGGGAGAATTTGACTCCTTCGAAATCCAGTACACAGATAGAGACGGGCAACTCCAAATGGTCCGCATAGGAGGTGACC
GGAATGACATCACCCTCTCTGGCCTGGAATCCGACCACAGATACCTGGTGACCCTGTATGGTTTCAGTGATGGGAAGCATGTAGGTCCTG
TCCATGTCGAGGCCCTGACAGTCCCGGAGGAGGAGAAGCCTTCAGAACCTCCCACCGCAACCCCCGAGCCCCCCATCAAGCCTCGCCTGG
GGGAGCTGACCGTGACAGATGCCACCCCTGACTCCCTCAGCCTGTCCTGGACAGTTCCCGAGGGACAGTTTGACCACTTCCTGGTCCAGT
ACAGGAATGGAGATGGGCAGCCCAAGGCAGTGAGGGTGCCAGGGCACGAGGAAGGGGTCACCATCTCGGGCCTGGAGCCAGACCATAAAT
ACAAGATGAACCTGTACGGCTTCCACGGTGGCCAGCGCATGGGCCCTGTGTCTGTCGTCGGGGTGACAGCTGCAGAGGAAGAGACCCCCA
GCCCCACAGAACCCAGCATGGAGGCCCCGGAGCCCGCTGAGGAGCCGCTCCTGGGGGAGCTAACAGTGACAGGATCCTCCCCTGACTCGC
TGAGCCTCTCCTGGACCGTCCCCCAGGGCCGCTTCGACTCCTTCACCGTGCAGTACAAGGACAGGGACGGGCGGCCCCAGGTGGTGCGTG
TTGGGGGCGAGGAGAGTGAAGTCACCGTGGGGGGCCTGGAGCCTGGGCGCAAGTACAAGATGCACCTGTACGGCCTCCACGAGGGGCGGC
GCGTGGGCCCAGTGTCTGCTGTGGGCGTCACGGCCCCCGAAGAGGAGTCCCCTGATGCTCCTCTTGCAAAGCTGCGCCTAGGGCAGATGA
CAGTGAGAGACATCACCTCCGACTCCCTCAGCCTCTCCTGGACAGTCCCCGAGGGCCAGTTTGACCATTTCTTGGTCCAGTTTAAGAATG
GGGACGGGCAGCCCAAGGCGGTGCGGGTGCCGGGACACGAGGATGGGGTCACCATCTCGGGCCTGGAGCCAGACCACAAGTACAAGATGA
ACCTGTACGGCTTCCACGGTGGCCAGCGCGTGGGCCCCGTGTCTGCTGTTGGTTTAACTGCCCCAGGAAAGGATGAAGAAATGGCCCCAG
CCTCGACAGAACCTCCCACCCCTGAACCCCCCATCAAGCCTCGCCTGGAGGAGCTGACCGTGACAGATGCGACCCCTGACTCCCTCAGCC
TGTCCTGGACGGTTCCCGAGGGACAGTTTGACCACTTCCTGGTCCAGTACAAGAATGGGGATGGGCAGCCCAAGGCAACACGGGTGCCAG
GACATGAGGACAGGGTCACCATCTCCGGCCTGGAGCCAGACAACAAGTACAAGATGAACCTGTACGGCTTCCACGGTGGCCAGCGTGTGG
GCCCCGTGTCTGCCATCGGGGTGACAGCTGCAGAGGAAGAGACCCCCAGCCCCACAGAACCCAGCATGGAGGCCCCGGAGCCCCCTGAGG
AGCCGCTCCTGGGGGAGCTAACAGTGACAGGATCCTCCCCTGACTCGCTGAGCCTCTCCTGGACCGTCCCCCAGGGCCGCTTCGACTCCT
TCACCGTGCAGTACAAGGACAGGGACGGGCGGCCCCAGGTGGTGCGTGTTGGGGGCGAGGAGAGCGAGGTCACCGTGGGGGGCCTGGAGC
CTGGGCGCAAATACAAGATGCACCTGTATGGCCTCCACGAGGGGCGGCGCGTGGGCCCGGTGTCCACCGTGGGCGTGACTGCCCCACAAG
AGGATGTGGACGAGACCCCCAGCCCTACAGAACCAGGCACAGAGGCCCCAGGGCCCCCCGAGGAGCCTCTCCTGGGGGAGCTGACAGTGA
CAGGATCCTCCCCTGACTCGCTGAGCCTTTCCTGGACCGTCCCCCAGGGCCGCTTTGACTCCTTCACCGTGCAGTACAAGGACAGGGACG
GGCGGCCCCAGGCGGTGCGTGTTGGGGGCCAGGAGAGCAAGGTCACTGTGAGGGGCCTGGAGCCTGGGCGCAAGTACAAGATGCACCTGT
ACGGCCTCCACGAGGGGCGGCGCCTGGGCCCGGTGTCTGCCGTGGGCGTCACAGAGGATGAAGCCGAGACCACCCAAGCAGTGCCTACCA
TGACCCCTGAGCCCCCCATCAAGCCTCGCCTGGGGGAGCTGACCATGACAGATGCCACCCCTGACTCCCTCAGCCTGTCCTGGACGGTTC
CCGAGGGCCAGTTTGACCACTTCCTGGTCCAGTACAGGAATGGGGATGGGCAGCCCAAGGCGGTGCGGGTGCCGGGGCACGAGGACGGGG
TCACCATCTCAGGCCTGGAGCCAGACCATAAATACAAGATGAACCTGTACGGCTTCCACGGTGGCCAGCGCGTGGGCCCCATCTCTGTCA
TTGGGGTGACGGCTGCAGAGGAAGAGACCCCCAGCCCCACGGAACTCAGCACTGAGGCCCCGGAGCCCCCTGAGGAGCCGCTCCTGGGGG
AGCTGACAGTGACAGGATCCTCCCCTGACTCGCTGAGCCTCTCCTGGACCATCCCCCAGGGCCACTTCGACTCCTTCACCGTGCAGTACA
AGGACAGGGACGGGCGGCCCCAGGTGATGCGTGTCAGGGGCGAGGAGAGCGAGGTCACCGTGGGGGGCCTGGAGCCCGGGCGCAAATACA
AGATGCACCTGTACGGCCTCCACGAGGGGCGGCGTGTGGGCCCGGTGTCCACCGTGGGTGTGACAGCTCCAGAGGATGAAGCAGAGACCA
CCCAAGCAGTGCCCACCACAACCCCTGAGCCCCCCAACAAGCCTCGCCTCGGGGAGCTGACCGTGACAGATGCCACCCCTGACTCCCTCA
GCCTGTCCTGGATGGTCCCCGAGGGCCAGTTTGACCACTTCCTGGTCCAGTACAGGAATGGGGATGGGCAGCCCAAGGTGGTGCGGGTGC
CGGGGCACGAGGACGGGGTCACCATCTCAGGCCTGGAGCCAGACCACAAGTACAAGATGAACCTGTACGGCTTCCACGGTGGCCAGCGCG
TGGGCCCCATCTCTGTCATTGGGGTGACAGCTGCAGAGGAAGAAACTCCCGCCCCCACAGAACCCAGCACGGAGGCCCCGGAGCCCCCTG
AGGAGCCGCTCCTGGGGGAGCTGACAGTGACAGGATCCTCCCCTGACTCGCTGAGCCTCTCCTGGACCATCCCCCAGGGCCGCTTCGACT
CCTTCACTGTGCAGTACAAGGACAGGGACGGGCGGCCCCAGGTGGTGCGTGTCAGGGGCGAGGAGAGCGAGGTCACCGTGGGGGGCCTGG
AGCCCGGGTGCAAATACAAGATGCACCTGTACGGCCTCCACGAGGGGCAGCGCGTGGGCCCAGTGTCCGCTGTGGGTGTGACAGCTCCAA
AGGATGAAGCCGAGACCACCCAAGCAGTGCCTACCATGACCCCTGAGCCCCCCATCAAGCCTCGCCTGGGGGAGCTGACCGTGACAGATG
CCACCCCCGACTCCCTCAGCCTGTCCTGGATGGTTCCCGAGGGCCAGTTTGACCACTTCCTGGTCCAGTACAGGAATGGGGATGGGCAGC
CCAAGGCGGTGCGGGTGCCGGGGCACGAGGACGGGGTCACCATCTCAGGCCTGGAGCCAGACCATAAATACAAGATGAACCTGTACGGCT
TCCACGGTGGCCAGCGCGTAGGCCCTGTGTCTGCCATTGGGGTGACGGAGGAAGAGACCCCCAGCCCCACAGAACCCAGCACTGAGGCCC
CGGAGGCCCCTGAGGAGCCGCTCCTGGGGGAGTTGACAGTGACAGGATCCTCCCCTGACTCGCTGAGCCTCTCCTGGACCGTCCCCCAGG
GCCGCTTCGACTCCTTCACCGTGCAGTACAAGGACAGGGACGGGCAGCCCCAGGTGGTGCGTGTCAGGGGCGAGGAGAGCGAGGTCACCG
TGGGGGGCCTGGAGCCCGGGCGCAAATACAAGATGCATCTGTACGGCCTCCACGAGGGGCAGCGCGTGGGCCCAGTGTCCACCGTGGGCA
TCACGGCGCCCCTGCCCACACCACTGCCGGTGGAGCCCCGCCTGGGGGAGCTGGCGGTGGCGGCCGTGACCTCGGACTCAGTGGGCCTCT
CATGGACGGTGGCCCAGGGCCCCTTTGACTCCTTCCTGGTACAGTACAGGGACGCGCAGGGGCAGCCCCAGGCAGTGCCTGTGAGCGGAG
ACCTCCGAGCGGTCGCCGTCTCGGGGCTGGACCCGGCCCGCAAGTACAAGTTCCTGCTCTTTGGACTCCAGAATGGGAAACGCCACGGCC
CAGTCCCTGTGGAGGCCAGGACCGCCCCAGACACCAAACCGTCTCCCCGCCTGGGGGAGCTGACTGTGACAGATGCGACCCCTGACTCCG
TGGGCCTCTCGTGGACGGTCCCTGAGGGCGAATTCGACTCCTTCGTGGTCCAGTACAAGGATAAGGATGGTCGGCTCCAGGTGGTGCCGG
TGGCAGCCAACCAGCGGGAGGTCACAGTCCAGGGCCTGGAGCCCAGTAGGAAATACAGGTTCCTGCTCTATGGTCTGTCAGGCAGGAAAC
GACTGGGCCCCATCTCTGCTGACAGCACCACAGCTCCCCTGGAGAAGGAGCTACCTCCCCACCTGGGGGAACTGACCGTGGCTGAGGAGA
CCTCCAGCTCTCTGCGCCTGTCCTGGACGGTAGCCCAGGGCCCCTTTGACTCCTTCGTGGTCCAGTACAGGGACACGGACGGGCAGCCCA
GGGCAGTGCCTGTGGCCGCAGACCAGCGCACAGTCACCGTAGAGGACCTGGAGCCTGGCAAGAAATACAAGTTTCTGCTCTACGGGCTCC
TTGGGGGAAAGCGCCTGGGCCCGGTCTCTGCCCTGGGAATGACAGCCCCAGAAGAGGACACACCAGCCCCAGAGTTAGCCCCAGAGGCCC
CTGAGCCTCCTGAAGAGCCCCGCCTAGGAGTGCTGACCGTGACCGACACAACCCCAGACTCCATGCGCCTCTCGTGGAGCGTGGCCCAGG
GCCCCTTTGATTCCTTCGTGGTCCAGTATGAGGACACGAACGGGCAGCCCCAGGCCTTGCTCGTGGACGGCGACCAGAGCAAGATCCTCA
TCTCAGGCCTGGAGCCCAGCACCCCCTACAGGTTCCTCCTCTATGGCCTCCATGAAGGGAAGCGCCTGGGGCCCCTCTCAGCTGAGGGCA
CCACAGGGCTGGCTCCTGCTGGTCAGACCTCAGAGGAGTCAAGGCCCCGCCTGTCCCAGCTGTCTGTGACTGACGTGACCACCAGTTCAC
TGAGGCTCAACTGGGAGGCCCCACCGGGGGCCTTCGACTCCTTCCTGCTCCGCTTTGGGGTTCCATCACCAAGCACTCTGGAGCCGCATC
CGCGTCCACTGCTGCAGCGCGAGCTGATGGTGCCGGGGACGCGGCACTCGGCCGTGCTCCGGGACCTGCGTTCCGGGACTCTGTACAGCC
TGACACTGTATGGGCTGCGAGGACCCCACAAGGCCGACAGCATCCAGGGAACCGCCCGCACCCTCAGCCCAGTTCTGGAGAGCCCCCGTG
ACCTCCAATTCAGTGAAATCAGGGAGACCTCAGCCAAGGTCAACTGGATGCCCCCACCATCCCGGGCGGACAGCTTCAAAGTCTCCTACC
AGCTGGCGGACGGAGGGGAGCCTCAGAGTGTGCAGGTGGATGGCCAGGCCCGGACCCAGAAACTCCAGGGGCTGATCCCAGGCGCTCGCT
ATGAGGTGACCGTGGTCTCGGTCCGAGGCTTTGAGGAGAGTGAGCCTCTCACAGGCTTCCTCACCACGGTTCCTGACGGTCCCACACAGT
TGCGTGCACTGAACTTGACCGAGGGATTCGCCGTGCTGCACTGGAAGCCCCCCCAGAATCCTGTGGACACCTATGACGTCCAGGTCACAG
CCCCTGGGGCCCCGCCTCTGCAGGCGGAGACCCCAGGCAGCGCGGTGGACTACCCCCTGCATGACCTTGTCCTCCACACCAACTACACCG
CCACAGTGCGTGGCCTGCGGGGCCCCAACCTCACTTCCCCAGCCAGCATCACCTTCACCACAGGGCTAGAGGCCCCTCGGGACTTGGAGG
CCAAGGAAGTGACCCCCCGCACCGCCCTGCTCACTTGGACTGAGCCCCCAGTCCGGCCCGCAGGCTACCTGCTCAGCTTCCACACCCCTG
GTGGACAGAACCAGGAGATCCTGCTCCCAGGAGGGATCACATCTCACCAGCTCCTTGGCCTCTTTCCCTCCACCTCCTACAATGCACGGC
TCCAGGCCATGTGGGGCCAGAGCCTCCTGCCGCCCGTGTCCACCTCTTTCACCACGGGTGGGCTGCGGATCCCCTTCCCCAGGGACTGCG
GGGAGGAGATGCAGAACGGAGCCGGTGCCTCCAGGACCAGCACCATCTTCCTCAACGGCAACCGCGAGCGGCCCCTGAACGTGTTTTGCG
ACATGGAGACTGATGGGGGCGGCTGGCTGGTGTTCCAGCGCCGCATGGATGGACAGACAGACTTCTGGAGGGACTGGGAGGACTATGCCC
ATGGTTTTGGGAACATCTCTGGAGAGTTCTGGCTGGGCAATGAGGCCCTGCACAGCCTGACACAGGCAGGTGACTACTCCATGCGCGTGG
ACCTGCGGGCTGGGGACGAGGCTGTGTTCGCCCAGTACGACTCCTTCCACGTAGACTCGGCTGCGGAGTACTACCGCCTCCACTTGGAGG
GCTACCACGGCACCGCAGGGGACTCCATGAGCTACCACAGCGGCAGTGTCTTCTCTGCCCGTGATCGGGACCCCAACAGCTTGCTCATCT
CCTGCGCTGTCTCCTACCGAGGGGCCTGGTGGTACAGGAACTGCCACTACGCCAACCTCAACGGGCTCTACGGGAGCACAGTGGACCATC
AGGGAGTGAGCTGGTACCACTGGAAGGGCTTCGAGTTCTCGGTGCCCTTCACGGAAATGAAGCTGAGACCAAGAAACTTTCGCTCCCCAG
CGGGGGGAGGCTGAGCTGCTGCCCACCTCTCTCGCACCCCAGTATGACTGCCGAGCACTGAGGGGTCGCCCCGAGAGAAGAGCCAGGGTC
CTTCACCACCCAGCCGCTGGAGGAAGCCTTCTCTGCCAGCGATCTCGCAGCACTGTGTTTACAGGGGGGAGGGGAGGGGTTCGTACGGGA


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FusionGenePPI for DSG1_TNXB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
DSG1SSSCA1, PKP3, PKP2, DSC2, JUP, PKP1, DSC1, OTUD4, USP1, USP53, KHDRBS2, PPP2R2A, CUL2, CDK2, COPS5, ESR1, IQCB1, MAPK7, CEP76, TUBG1, CCDC8, HNRNPA1, NTRK1, PLK1, IQGAP1, SAMD1, MCM2, MCM5, UBXN1, CDC73, CCDC51, PI4KA, TBC1D22B, VAV1, C21orf59, CYLD, COQ2, SOAT1, TRIM25TNXBBANP, FIGNL1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for DSG1_TNXB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for DSG1_TNXB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneDSG1C0011603Dermatitis1CTD_human
HgeneDSG1C0020517Hypersensitivity1CTD_human
HgeneDSG1C0025517Metabolic Diseases1CTD_human
TgeneTNXBC0036341Schizophrenia3PSYGENET
TgeneTNXBC1848029Ehlers-Danlos syndrome caused by tenascin-X deficiency2CTD_human;ORPHANET;UNIPROT
TgeneTNXBC4014831VESICOURETERAL REFLUX 81UNIPROT