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Fusion gene ID: 1048 |
FusionGeneSummary for AGAP1_ATG4B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: AGAP1_ATG4B | Fusion gene ID: 1048 | Hgene | Tgene | Gene symbol | AGAP1 | ATG4B | Gene ID | 116987 | 23192 |
| Gene name | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | autophagy related 4B cysteine peptidase | |
| Synonyms | AGAP-1|CENTG2|GGAP1|cnt-g2 | APG4B|AUTL1 | |
| Cytomap | 2q37.2 | 2q37.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1GTP-binding and GTPase-activating protein 1centaurin, gamma 2 | cysteine protease ATG4BAPG4 autophagy 4 homolog BATG4 autophagy related 4 homolog BAUT-like 1 cysteine endopeptidaseautophagin-1autophagy-related cysteine endopeptidase 1autophagy-related protein 4 homolog BhAPG4B | |
| Modification date | 20180523 | 20180526 | |
| UniProtAcc | Q9UPQ3 | Q9Y4P1 | |
| Ensembl transtripts involved in fusion gene | ENST00000336665, ENST00000304032, ENST00000409538, ENST00000428334, ENST00000409457, | ENST00000405546, ENST00000402096, ENST00000404914, ENST00000491867, ENST00000396411, ENST00000474739, | |
| Fusion gene scores | * DoF score | 25 X 11 X 14=3850 | 2 X 1 X 2=4 |
| # samples | 26 | 2 | |
| ** MAII score | log2(26/3850*10)=-3.88827491744117 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: AGAP1 [Title/Abstract] AND ATG4B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ATG4B | GO:0006508 | proteolysis | 15169837|18387192 |
| Tgene | ATG4B | GO:0006914 | autophagy | 18387192 |
| Tgene | ATG4B | GO:0051697 | protein delipidation | 25327288 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A3U7-01A | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000336665 | ENST00000405546 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000336665 | ENST00000402096 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000336665 | ENST00000404914 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-3UTR | ENST00000336665 | ENST00000491867 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000336665 | ENST00000396411 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000336665 | ENST00000474739 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| In-frame | ENST00000304032 | ENST00000405546 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000304032 | ENST00000402096 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000304032 | ENST00000404914 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-3UTR | ENST00000304032 | ENST00000491867 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000304032 | ENST00000396411 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000304032 | ENST00000474739 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-3CDS | ENST00000409538 | ENST00000405546 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-5UTR | ENST00000409538 | ENST00000402096 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-5UTR | ENST00000409538 | ENST00000404914 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-3UTR | ENST00000409538 | ENST00000491867 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-5UTR | ENST00000409538 | ENST00000396411 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-5UTR | ENST00000409538 | ENST00000474739 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-3CDS | ENST00000428334 | ENST00000405546 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-5UTR | ENST00000428334 | ENST00000402096 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-5UTR | ENST00000428334 | ENST00000404914 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-3UTR | ENST00000428334 | ENST00000491867 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-5UTR | ENST00000428334 | ENST00000396411 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| intron-5UTR | ENST00000428334 | ENST00000474739 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| In-frame | ENST00000409457 | ENST00000405546 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000409457 | ENST00000402096 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000409457 | ENST00000404914 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-3UTR | ENST00000409457 | ENST00000491867 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000409457 | ENST00000396411 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
| 5CDS-5UTR | ENST00000409457 | ENST00000474739 | AGAP1 | chr2 | 236403493 | + | ATG4B | chr2 | 242590425 | + |
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FusionProtFeatures for AGAP1_ATG4B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| AGAP1 | ATG4B |
| GTPase-activating protein for ARF1 and, to a lesserextent, ARF5. Directly and specifically regulates the adapterprotein 3 (AP-3)-dependent trafficking of proteins in theendosomal-lysosomal system. {ECO:0000269|PubMed:12640130}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000304032 | + | 1 | 18 | 346_588 | 54 | 858 | Domain | PH |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000304032 | + | 1 | 18 | 609_729 | 54 | 858 | Domain | Arf-GAP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000336665 | + | 1 | 17 | 346_588 | 54 | 805 | Domain | PH |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000336665 | + | 1 | 17 | 609_729 | 54 | 805 | Domain | Arf-GAP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000409457 | + | 1 | 10 | 346_588 | 54 | 406 | Domain | PH |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000409457 | + | 1 | 10 | 609_729 | 54 | 406 | Domain | Arf-GAP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000304032 | + | 1 | 18 | 122_126 | 54 | 858 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000304032 | + | 1 | 18 | 178_181 | 54 | 858 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000304032 | + | 1 | 18 | 78_85 | 54 | 858 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000336665 | + | 1 | 17 | 122_126 | 54 | 805 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000336665 | + | 1 | 17 | 178_181 | 54 | 805 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000336665 | + | 1 | 17 | 78_85 | 54 | 805 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000409457 | + | 1 | 10 | 122_126 | 54 | 406 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000409457 | + | 1 | 10 | 178_181 | 54 | 406 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000409457 | + | 1 | 10 | 78_85 | 54 | 406 | Nucleotide binding | GTP |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000304032 | + | 1 | 18 | 66_276 | 54 | 858 | Region | Note=Small GTPase-like |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000336665 | + | 1 | 17 | 66_276 | 54 | 805 | Region | Note=Small GTPase-like |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000409457 | + | 1 | 10 | 66_276 | 54 | 406 | Region | Note=Small GTPase-like |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000304032 | + | 1 | 18 | 768_797 | 54 | 858 | Repeat | Note=ANK 1 |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000304032 | + | 1 | 18 | 801_830 | 54 | 858 | Repeat | Note=ANK 2 |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000336665 | + | 1 | 17 | 768_797 | 54 | 805 | Repeat | Note=ANK 1 |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000336665 | + | 1 | 17 | 801_830 | 54 | 805 | Repeat | Note=ANK 2 |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000409457 | + | 1 | 10 | 768_797 | 54 | 406 | Repeat | Note=ANK 1 |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000409457 | + | 1 | 10 | 801_830 | 54 | 406 | Repeat | Note=ANK 2 |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000304032 | + | 1 | 18 | 624_647 | 54 | 858 | Zinc finger | C4-type |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000336665 | + | 1 | 17 | 624_647 | 54 | 805 | Zinc finger | C4-type |
| Hgene | >AGAP1 | chr2:236403493 | chr2:242590425 | ENST00000409457 | + | 1 | 10 | 624_647 | 54 | 406 | Zinc finger | C4-type |
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FusionGeneSequence for AGAP1_ATG4B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_AGAP1_ENST00000336665_chr2_236403493_+_ATG4B_ENST00000405546_chr2_242590425_+_432aa MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEK DEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIA QMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPW RPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMS >In-frame_AGAP1_ENST00000304032_chr2_236403493_+_ATG4B_ENST00000405546_chr2_242590425_+_432aa MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEK DEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIA QMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPW RPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMS >In-frame_AGAP1_ENST00000409457_chr2_236403493_+_ATG4B_ENST00000405546_chr2_242590425_+_432aa MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEK DEILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKDSYYSIHQIA QMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPW RPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFHCQHPPCRMS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_AGAP1_ENST00000336665_chr2_236403493_+_ATG4B_ENST00000405546_chr2_242590425_+_1296nt ATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATC TACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGAC ACTCTCCGGTTTGCTGAGTTTGAAGATTTTCCTGAGACCTCAGAGCCCGTTTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAG GACGAGATCTTGTCTGATGTGGCATCTAGACTTTGGTTTACATACAGGAAAAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGAC ACAGGCTGGGGCTGCATGCTGCGGTGTGGACAGATGATCTTTGCCCAAGCCCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACA CAAAGGAAGAGGCAGCCAGACAGCTACTTCAGCGTCCTCAACGCATTCATCGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCG CAAATGGGAGTTGGCGAAGGCAAGTCCATAGGCCAGTGGTACGGGCCCAACACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGAT ACGTGGAGCTCCTTGGCGGTCCACATTGCAATGGACAACACTGTTGTGATGGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGT GCAGGCGCCACTGCGTTTCCTGCAGATTCCGACCGGCACTGCAACGGATTCCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGG AGACCCCTGGTACTTCTCATTCCCCTGCGCCTGGGGCTCACGGACATCAACGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATG CCCCAGTCCCTGGGCGTCATCGGAGGGAAGCCCAACAGCGCCCACTACTTCATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCC CACACCACGCAGCCAGCCGTGGAGCCCACTGATGGCTGCTTCATCCCGGACGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGC ATCGCGGAGCTTGACCCGTCCATCGCTGTGGGGTTTTTCTGTAAGACTGAAGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTG TCTCTGCTTGGAGGTGCCCTGCCCATGTTTGAGCTGGTGGAGCTGCAGCCTTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTA >In-frame_AGAP1_ENST00000304032_chr2_236403493_+_ATG4B_ENST00000405546_chr2_242590425_+_1296nt ATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATC TACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGAC ACTCTCCGGTTTGCTGAGTTTGAAGATTTTCCTGAGACCTCAGAGCCCGTTTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAG GACGAGATCTTGTCTGATGTGGCATCTAGACTTTGGTTTACATACAGGAAAAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGAC ACAGGCTGGGGCTGCATGCTGCGGTGTGGACAGATGATCTTTGCCCAAGCCCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACA CAAAGGAAGAGGCAGCCAGACAGCTACTTCAGCGTCCTCAACGCATTCATCGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCG CAAATGGGAGTTGGCGAAGGCAAGTCCATAGGCCAGTGGTACGGGCCCAACACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGAT ACGTGGAGCTCCTTGGCGGTCCACATTGCAATGGACAACACTGTTGTGATGGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGT GCAGGCGCCACTGCGTTTCCTGCAGATTCCGACCGGCACTGCAACGGATTCCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGG AGACCCCTGGTACTTCTCATTCCCCTGCGCCTGGGGCTCACGGACATCAACGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATG CCCCAGTCCCTGGGCGTCATCGGAGGGAAGCCCAACAGCGCCCACTACTTCATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCC CACACCACGCAGCCAGCCGTGGAGCCCACTGATGGCTGCTTCATCCCGGACGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGC ATCGCGGAGCTTGACCCGTCCATCGCTGTGGGGTTTTTCTGTAAGACTGAAGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTG TCTCTGCTTGGAGGTGCCCTGCCCATGTTTGAGCTGGTGGAGCTGCAGCCTTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTA >In-frame_AGAP1_ENST00000409457_chr2_236403493_+_ATG4B_ENST00000405546_chr2_242590425_+_1296nt ATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATC TACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGAC ACTCTCCGGTTTGCTGAGTTTGAAGATTTTCCTGAGACCTCAGAGCCCGTTTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAG GACGAGATCTTGTCTGATGTGGCATCTAGACTTTGGTTTACATACAGGAAAAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGAC ACAGGCTGGGGCTGCATGCTGCGGTGTGGACAGATGATCTTTGCCCAAGCCCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACA CAAAGGAAGAGGCAGCCAGACAGCTACTTCAGCGTCCTCAACGCATTCATCGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCG CAAATGGGAGTTGGCGAAGGCAAGTCCATAGGCCAGTGGTACGGGCCCAACACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGAT ACGTGGAGCTCCTTGGCGGTCCACATTGCAATGGACAACACTGTTGTGATGGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGT GCAGGCGCCACTGCGTTTCCTGCAGATTCCGACCGGCACTGCAACGGATTCCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGG AGACCCCTGGTACTTCTCATTCCCCTGCGCCTGGGGCTCACGGACATCAACGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATG CCCCAGTCCCTGGGCGTCATCGGAGGGAAGCCCAACAGCGCCCACTACTTCATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCC CACACCACGCAGCCAGCCGTGGAGCCCACTGATGGCTGCTTCATCCCGGACGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGC ATCGCGGAGCTTGACCCGTCCATCGCTGTGGGGTTTTTCTGTAAGACTGAAGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTG TCTCTGCTTGGAGGTGCCCTGCCCATGTTTGAGCTGGTGGAGCTGCAGCCTTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_AGAP1_ENST00000336665_chr2_236403493_+_ATG4B_ENST00000405546_chr2_242590425_+_3525nt CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG GGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGACACTCTCCGGTTTGCTGAGTTTGAAGATTTTCCTGAGACCTCAGAGCCCGT TTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAGGACGAGATCTTGTCTGATGTGGCATCTAGACTTTGGTTTACATACAGGAA AAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGACACAGGCTGGGGCTGCATGCTGCGGTGTGGACAGATGATCTTTGCCCAAGC CCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACACAAAGGAAGAGGCAGCCAGACAGCTACTTCAGCGTCCTCAACGCATTCAT CGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCGCAAATGGGAGTTGGCGAAGGCAAGTCCATAGGCCAGTGGTACGGGCCCAA CACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGATACGTGGAGCTCCTTGGCGGTCCACATTGCAATGGACAACACTGTTGTGAT GGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGTGCAGGCGCCACTGCGTTTCCTGCAGATTCCGACCGGCACTGCAACGGATT CCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGACCCCTGGTACTTCTCATTCCCCTGCGCCTGGGGCTCACGGACATCAA CGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATGCCCCAGTCCCTGGGCGTCATCGGAGGGAAGCCCAACAGCGCCCACTACTT CATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCCCACACCACGCAGCCAGCCGTGGAGCCCACTGATGGCTGCTTCATCCCGGA CGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGCATCGCGGAGCTTGACCCGTCCATCGCTGTGGGGTTTTTCTGTAAGACTGA AGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTGTCTCTGCTTGGAGGTGCCCTGCCCATGTTTGAGCTGGTGGAGCTGCAGCC TTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTAGGTGAGAGCTGCCAAGTCCAGATTCTTCTGATGTAGAGCGACTGGAAAGA TTCTTCGACTCAGAAGATGAAGACTTTGAAATCCTGTCCCTTTGAAAATCCTGGGGTCGGGGGTGGCACCTGTGAGAGCCTGGGGCTCCT GGTGCCGCTGCGTTTCATCCATCCCGCCCGCTCGCCTGCCGAGGGCTGCGCCCCGTGCTGCCTCCCCCCAGAGGGCCACCCGCTGTGCTC GTGGACTGAGGCTGCGCTGCCCGGGAGGCCTTACTGCTTGGTGTCAGACTGCCCAGCTCAGAGTGCCCGTCAGGGCCTGTGCATCCGCAC GCGGAGCCGTCTGTTAGGAGCTTCCAGAGTGTTCTCTCGACACTGCCAGCCCCGTGTTAGCACCTGGGCCTCAGTCCCACTTGCTCCCAG GCGCCGGTTCTGTGGTTGGTTTGGAATTAAAGTCCTGTTTGAAGTTGTCAGACACAGACATGAATTTCTGGGCGCTCCCTGAGTCAGAGT CTCAGAAGACCTGTGCAGGCTGGCGTGAGAGGAGCGGCAGCCACACTGCGGCCCCACGCCCAAGGACTGGGCTGCTCTCGAGGGGGGCGC GCCCACCGCTGTGTCCTCTCTGCCCAGCCTGGCTTACCAAGGGCTACCTCAGTGGGAGATGAGGTTGGAGGAACGAAGGCGAGGTTCCTC CTTGCTTTGGGGAGAAAAGTATTCAGGAAGTGGGTGTGTGGGAAACCTGAAGATGGCGTGCACAGGACACAGCGTGGGCGGCCTGGGCAG AAGGGCGGCTGGCTGTCCTGGAGCTGCTGCTGGAGCCTGCCCTCAGAGTGTCCCTTTCCAGTGCTGTGGCATTCTGTGGCAGCTTCCCCA GGTGTGGTGACGGGGGGGGGGCGGGGCCTCCACCTGTGACAGCCAGGCTTGAGGGTGGACGGCGTGCCTCTCCCAGGAGCCTTCCCCATG TCCTTGCCTTGCTGAGAATTGCCCTCCCATGCCGCTGAGGTGTTAGGTGGTTTAGGGCCAAAAGGGGAAAACCACTTGAGTCTTGTGGTG TGTGGTGGGCAGACACCACAGGGTGGCATCACCTGGTGGCATTTCCAGAACCTCAGCCCCGATTCCAGCACCCACCACCGCCTGACCCTG TGTAACCTGCTGTCCCGGGTCCCAGAGTGCACTCTGCCCCGCTGCTCTGCTGCCTGTCCTGGGAAAGTATCTTTGCCCCACTAGGAAATG TAAACAGGAGGGCTTGGGGAGCGTGGGCACTTTTCTCATGAGCAGCTACTGCGGCGTTGGCAGGACTCGCTGCTGCTGCTGCTGCTTGTG TAGGTCGGGGAGCCAGAGATCCCCGAGGACGCGCGCCGGACAGTCGGCACTGACCGGCCCACCTGGTAGCAGAGGACACCCCCAGCCCCC CAAGCATTGAAGACATAGTGTATTTCCTCGTATCCTTTCTCCCTTGGGTGTAGTTGGGGTGGGGAAGCAGGGAAGGCTGGTGCGATCTCC ATTCCTTGGGCTCCACGTCCGAGTTCATGGTGCGCCGCTGTGCTGGGAGCTGCAGTGGTAATGTGTGGGACACCTTGACCAAAGGGGAGC TTTGTCTCGTGTGTTTTGAAAAAGGCTTAATGAAGAGAATGTTGTTCATTCTTAGTAGTATAGTTTGCAATTCTTAATGGCAAATAATAA >In-frame_AGAP1_ENST00000304032_chr2_236403493_+_ATG4B_ENST00000405546_chr2_242590425_+_3525nt CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG GGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGACACTCTCCGGTTTGCTGAGTTTGAAGATTTTCCTGAGACCTCAGAGCCCGT TTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAGGACGAGATCTTGTCTGATGTGGCATCTAGACTTTGGTTTACATACAGGAA AAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGACACAGGCTGGGGCTGCATGCTGCGGTGTGGACAGATGATCTTTGCCCAAGC CCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACACAAAGGAAGAGGCAGCCAGACAGCTACTTCAGCGTCCTCAACGCATTCAT CGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCGCAAATGGGAGTTGGCGAAGGCAAGTCCATAGGCCAGTGGTACGGGCCCAA CACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGATACGTGGAGCTCCTTGGCGGTCCACATTGCAATGGACAACACTGTTGTGAT GGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGTGCAGGCGCCACTGCGTTTCCTGCAGATTCCGACCGGCACTGCAACGGATT CCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGACCCCTGGTACTTCTCATTCCCCTGCGCCTGGGGCTCACGGACATCAA CGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATGCCCCAGTCCCTGGGCGTCATCGGAGGGAAGCCCAACAGCGCCCACTACTT CATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCCCACACCACGCAGCCAGCCGTGGAGCCCACTGATGGCTGCTTCATCCCGGA CGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGCATCGCGGAGCTTGACCCGTCCATCGCTGTGGGGTTTTTCTGTAAGACTGA AGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTGTCTCTGCTTGGAGGTGCCCTGCCCATGTTTGAGCTGGTGGAGCTGCAGCC TTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTAGGTGAGAGCTGCCAAGTCCAGATTCTTCTGATGTAGAGCGACTGGAAAGA TTCTTCGACTCAGAAGATGAAGACTTTGAAATCCTGTCCCTTTGAAAATCCTGGGGTCGGGGGTGGCACCTGTGAGAGCCTGGGGCTCCT GGTGCCGCTGCGTTTCATCCATCCCGCCCGCTCGCCTGCCGAGGGCTGCGCCCCGTGCTGCCTCCCCCCAGAGGGCCACCCGCTGTGCTC GTGGACTGAGGCTGCGCTGCCCGGGAGGCCTTACTGCTTGGTGTCAGACTGCCCAGCTCAGAGTGCCCGTCAGGGCCTGTGCATCCGCAC GCGGAGCCGTCTGTTAGGAGCTTCCAGAGTGTTCTCTCGACACTGCCAGCCCCGTGTTAGCACCTGGGCCTCAGTCCCACTTGCTCCCAG GCGCCGGTTCTGTGGTTGGTTTGGAATTAAAGTCCTGTTTGAAGTTGTCAGACACAGACATGAATTTCTGGGCGCTCCCTGAGTCAGAGT CTCAGAAGACCTGTGCAGGCTGGCGTGAGAGGAGCGGCAGCCACACTGCGGCCCCACGCCCAAGGACTGGGCTGCTCTCGAGGGGGGCGC GCCCACCGCTGTGTCCTCTCTGCCCAGCCTGGCTTACCAAGGGCTACCTCAGTGGGAGATGAGGTTGGAGGAACGAAGGCGAGGTTCCTC CTTGCTTTGGGGAGAAAAGTATTCAGGAAGTGGGTGTGTGGGAAACCTGAAGATGGCGTGCACAGGACACAGCGTGGGCGGCCTGGGCAG AAGGGCGGCTGGCTGTCCTGGAGCTGCTGCTGGAGCCTGCCCTCAGAGTGTCCCTTTCCAGTGCTGTGGCATTCTGTGGCAGCTTCCCCA GGTGTGGTGACGGGGGGGGGGCGGGGCCTCCACCTGTGACAGCCAGGCTTGAGGGTGGACGGCGTGCCTCTCCCAGGAGCCTTCCCCATG TCCTTGCCTTGCTGAGAATTGCCCTCCCATGCCGCTGAGGTGTTAGGTGGTTTAGGGCCAAAAGGGGAAAACCACTTGAGTCTTGTGGTG TGTGGTGGGCAGACACCACAGGGTGGCATCACCTGGTGGCATTTCCAGAACCTCAGCCCCGATTCCAGCACCCACCACCGCCTGACCCTG TGTAACCTGCTGTCCCGGGTCCCAGAGTGCACTCTGCCCCGCTGCTCTGCTGCCTGTCCTGGGAAAGTATCTTTGCCCCACTAGGAAATG TAAACAGGAGGGCTTGGGGAGCGTGGGCACTTTTCTCATGAGCAGCTACTGCGGCGTTGGCAGGACTCGCTGCTGCTGCTGCTGCTTGTG TAGGTCGGGGAGCCAGAGATCCCCGAGGACGCGCGCCGGACAGTCGGCACTGACCGGCCCACCTGGTAGCAGAGGACACCCCCAGCCCCC CAAGCATTGAAGACATAGTGTATTTCCTCGTATCCTTTCTCCCTTGGGTGTAGTTGGGGTGGGGAAGCAGGGAAGGCTGGTGCGATCTCC ATTCCTTGGGCTCCACGTCCGAGTTCATGGTGCGCCGCTGTGCTGGGAGCTGCAGTGGTAATGTGTGGGACACCTTGACCAAAGGGGAGC TTTGTCTCGTGTGTTTTGAAAAAGGCTTAATGAAGAGAATGTTGTTCATTCTTAGTAGTATAGTTTGCAATTCTTAATGGCAAATAATAA >In-frame_AGAP1_ENST00000409457_chr2_236403493_+_ATG4B_ENST00000405546_chr2_242590425_+_3543nt GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGCTACTCTGACCTACGACACTCTCCGGTTTGCTGAGTTTGAAGATTTTCC TGAGACCTCAGAGCCCGTTTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAGGACGAGATCTTGTCTGATGTGGCATCTAGACT TTGGTTTACATACAGGAAAAACTTTCCAGCCATTGGGGGGACAGGCCCCACCTCGGACACAGGCTGGGGCTGCATGCTGCGGTGTGGACA GATGATCTTTGCCCAAGCCCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACACAAAGGAAGAGGCAGCCAGACAGCTACTTCAG CGTCCTCAACGCATTCATCGACAGGAAGGACAGTTACTACTCCATTCACCAGATAGCGCAAATGGGAGTTGGCGAAGGCAAGTCCATAGG CCAGTGGTACGGGCCCAACACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGATACGTGGAGCTCCTTGGCGGTCCACATTGCAAT GGACAACACTGTTGTGATGGAGGAAATCAGAAGGTTGTGCAGGACCAGCGTTCCCTGTGCAGGCGCCACTGCGTTTCCTGCAGATTCCGA CCGGCACTGCAACGGATTCCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGACCCCTGGTACTTCTCATTCCCCTGCGCCT GGGGCTCACGGACATCAACGAGGCCTACGTGGAGACGCTGAAGCACTGCTTCATGATGCCCCAGTCCCTGGGCGTCATCGGAGGGAAGCC CAACAGCGCCCACTACTTCATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCCCACACCACGCAGCCAGCCGTGGAGCCCACTGA TGGCTGCTTCATCCCGGACGAGAGCTTCCACTGCCAGCACCCGCCGTGCCGCATGAGCATCGCGGAGCTTGACCCGTCCATCGCTGTGGG GTTTTTCTGTAAGACTGAAGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTGTCTCTGCTTGGAGGTGCCCTGCCCATGTTTGA GCTGGTGGAGCTGCAGCCTTCACATCTGGCCTGCCCCGACGTCCTGAACCTGTCCCTAGGTGAGAGCTGCCAAGTCCAGATTCTTCTGAT GTAGAGCGACTGGAAAGATTCTTCGACTCAGAAGATGAAGACTTTGAAATCCTGTCCCTTTGAAAATCCTGGGGTCGGGGGTGGCACCTG TGAGAGCCTGGGGCTCCTGGTGCCGCTGCGTTTCATCCATCCCGCCCGCTCGCCTGCCGAGGGCTGCGCCCCGTGCTGCCTCCCCCCAGA GGGCCACCCGCTGTGCTCGTGGACTGAGGCTGCGCTGCCCGGGAGGCCTTACTGCTTGGTGTCAGACTGCCCAGCTCAGAGTGCCCGTCA GGGCCTGTGCATCCGCACGCGGAGCCGTCTGTTAGGAGCTTCCAGAGTGTTCTCTCGACACTGCCAGCCCCGTGTTAGCACCTGGGCCTC AGTCCCACTTGCTCCCAGGCGCCGGTTCTGTGGTTGGTTTGGAATTAAAGTCCTGTTTGAAGTTGTCAGACACAGACATGAATTTCTGGG CGCTCCCTGAGTCAGAGTCTCAGAAGACCTGTGCAGGCTGGCGTGAGAGGAGCGGCAGCCACACTGCGGCCCCACGCCCAAGGACTGGGC TGCTCTCGAGGGGGGCGCGCCCACCGCTGTGTCCTCTCTGCCCAGCCTGGCTTACCAAGGGCTACCTCAGTGGGAGATGAGGTTGGAGGA ACGAAGGCGAGGTTCCTCCTTGCTTTGGGGAGAAAAGTATTCAGGAAGTGGGTGTGTGGGAAACCTGAAGATGGCGTGCACAGGACACAG CGTGGGCGGCCTGGGCAGAAGGGCGGCTGGCTGTCCTGGAGCTGCTGCTGGAGCCTGCCCTCAGAGTGTCCCTTTCCAGTGCTGTGGCAT TCTGTGGCAGCTTCCCCAGGTGTGGTGACGGGGGGGGGGCGGGGCCTCCACCTGTGACAGCCAGGCTTGAGGGTGGACGGCGTGCCTCTC CCAGGAGCCTTCCCCATGTCCTTGCCTTGCTGAGAATTGCCCTCCCATGCCGCTGAGGTGTTAGGTGGTTTAGGGCCAAAAGGGGAAAAC CACTTGAGTCTTGTGGTGTGTGGTGGGCAGACACCACAGGGTGGCATCACCTGGTGGCATTTCCAGAACCTCAGCCCCGATTCCAGCACC CACCACCGCCTGACCCTGTGTAACCTGCTGTCCCGGGTCCCAGAGTGCACTCTGCCCCGCTGCTCTGCTGCCTGTCCTGGGAAAGTATCT TTGCCCCACTAGGAAATGTAAACAGGAGGGCTTGGGGAGCGTGGGCACTTTTCTCATGAGCAGCTACTGCGGCGTTGGCAGGACTCGCTG CTGCTGCTGCTGCTTGTGTAGGTCGGGGAGCCAGAGATCCCCGAGGACGCGCGCCGGACAGTCGGCACTGACCGGCCCACCTGGTAGCAG AGGACACCCCCAGCCCCCCAAGCATTGAAGACATAGTGTATTTCCTCGTATCCTTTCTCCCTTGGGTGTAGTTGGGGTGGGGAAGCAGGG AAGGCTGGTGCGATCTCCATTCCTTGGGCTCCACGTCCGAGTTCATGGTGCGCCGCTGTGCTGGGAGCTGCAGTGGTAATGTGTGGGACA CCTTGACCAAAGGGGAGCTTTGTCTCGTGTGTTTTGAAAAAGGCTTAATGAAGAGAATGTTGTTCATTCTTAGTAGTATAGTTTGCAATT |
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FusionGenePPI for AGAP1_ATG4B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| AGAP1 | GRB7, TK1, SMN1, APP, SQSTM1, CBWD1, MIER2, XPO1, PRPF4, RHOA, ARF1, ARF6, RAC1, CDC42, P4HA3, PCDHA12, LZTS2, FLCN, PCDH20, PCDHA10, EPHA7, KCTD3, KIF13B, ZBTB21, KSR1, GIGYF1, LRFN1, DENND1A, SH3PXD2A, SRGAP2, EIF4E2, SIPA1L1, LIMA1, MAGI1, TESK2, DCLK1, ZNF638, SRSF12, SYDE1, CDC25B, CDK16, FAM110B, USP21, FAM53C, ANKRD34A, FAM110A, TBC1D25, PPM1H, MAPKAP1, MAST3, RTKN, DENND4C, HDAC4, RAB3IP, TIAM1, PHLDB2, NADK, GAB2, KIAA1804, NF1, CBY1, CGN, RASAL2, MELK, PLEKHA7, MLLT4, DEPDC1B, KIF1C, SH3BP4, CAMSAP2, PLEKHA5, NAV1, EDC3, TRIM25 | ATG4B | GABARAPL2, LINC00341, MAP1LC3B, GABARAP, FBXW11, AMBRA1, ATG10, ATG12, ATG3, GABARAPL1, KRT4, ANXA1, CAMKK2, MAP1LC3A, STK3, ULK1, SQSTM1, YWHAB, BAG3, SHMT2, MOV10, NXF1, FANK1, STK16, TES |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for AGAP1_ATG4B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for AGAP1_ATG4B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | AGAP1 | C0004352 | Autistic Disorder | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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