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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for ZFYVE16 |
 Gene summary |
| Gene information | Gene symbol | ZFYVE16 | Gene ID | 9765 |
| Gene name | zinc finger FYVE-type containing 16 | |
| Synonyms | PPP1R69 | |
| Cytomap | 5q14.1 | |
| Type of gene | protein-coding | |
| Description | zinc finger FYVE domain-containing protein 16endosome-associated FYVE-domain proteinprotein phosphatase 1, regulatory subunit 69zinc finger, FYVE domain containing 16 | |
| Modification date | 20180523 | |
| UniProtAcc | Q7Z3T8 | |
| Context | PubMed: ZFYVE16 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for ZFYVE16 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for ZFYVE16 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for ZFYVE16 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_436117 | 5 | 79703933:79703972:79707464:79707592:79729927:79730036 | 79707464:79707592 | ENSG00000039319.12 | ENST00000510158.1 |
| exon_skip_436120 | 5 | 79703933:79703972:79723310:79723364:79729927:79730036 | 79723310:79723364 | ENSG00000039319.12 | ENST00000505560.1 |
| exon_skip_436121 | 5 | 79703933:79703972:79729927:79730036:79732574:79732978 | 79729927:79730036 | ENSG00000039319.12 | ENST00000510995.1,ENST00000512558.1 |
| exon_skip_436123 | 5 | 79729927:79730036:79731580:79731673:79732574:79732978 | 79731580:79731673 | ENSG00000039319.12 | ENST00000509562.1 |
| exon_skip_436125 | 5 | 79732574:79734826:79735754:79735851:79738941:79739103 | 79735754:79735851 | ENSG00000039319.12 | ENST00000338008.5,ENST00000512558.1,ENST00000505560.1,ENST00000510158.1 |
| exon_skip_436130 | 5 | 79739021:79739103:79739612:79739739:79741081:79741224 | 79739612:79739739 | ENSG00000039319.12 | ENST00000509558.1 |
| exon_skip_436131 | 5 | 79741081:79741224:79743844:79744223:79745409:79745532 | 79743844:79744223 | ENSG00000039319.12 | ENST00000338008.5,ENST00000512558.1,ENST00000505560.1,ENST00000510158.1 |
| exon_skip_436132 | 5 | 79741081:79741224:79744101:79744223:79745409:79745532 | 79744101:79744223 | ENSG00000039319.12 | ENST00000511829.1 |
| exon_skip_436135 | 5 | 79751510:79751593:79752279:79752384:79752763:79752911 | 79752279:79752384 | ENSG00000039319.12 | ENST00000338008.5,ENST00000511829.1,ENST00000505560.1,ENST00000510158.1 |
| exon_skip_436137 | 5 | 79752763:79752911:79755232:79755313:79768579:79768742 | 79755232:79755313 | ENSG00000039319.12 | ENST00000338008.5,ENST00000511829.1,ENST00000505560.1,ENST00000512907.1,ENST00000510158.1 |
| exon_skip_436140 | 5 | 79755257:79755313:79768579:79768742:79769572:79769678 | 79768579:79768742 | ENSG00000039319.12 | ENST00000338008.5,ENST00000511829.1,ENST00000505560.1,ENST00000512907.1,ENST00000510158.1 |
| exon_skip_436141 | 5 | 79769572:79769678:79770481:79770649:79773037:79773130 | 79770481:79770649 | ENSG00000039319.12 | ENST00000338008.5,ENST00000511829.1,ENST00000513789.1,ENST00000505560.1,ENST00000512907.1,ENST00000510158.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for ZFYVE16 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_436117 | 5 | 79703933:79703972:79707464:79707592:79729927:79730036 | 79707464:79707592 | ENSG00000039319.12 | ENST00000510158.1 |
| exon_skip_436120 | 5 | 79703933:79703972:79723310:79723364:79729927:79730036 | 79723310:79723364 | ENSG00000039319.12 | ENST00000505560.1 |
| exon_skip_436121 | 5 | 79703933:79703972:79729927:79730036:79732574:79732978 | 79729927:79730036 | ENSG00000039319.12 | ENST00000512558.1,ENST00000510995.1 |
| exon_skip_436123 | 5 | 79729927:79730036:79731580:79731673:79732574:79732978 | 79731580:79731673 | ENSG00000039319.12 | ENST00000509562.1 |
| exon_skip_436125 | 5 | 79732574:79734826:79735754:79735851:79738941:79739103 | 79735754:79735851 | ENSG00000039319.12 | ENST00000338008.5,ENST00000510158.1,ENST00000505560.1,ENST00000512558.1 |
| exon_skip_436130 | 5 | 79739021:79739103:79739612:79739739:79741081:79741224 | 79739612:79739739 | ENSG00000039319.12 | ENST00000509558.1 |
| exon_skip_436131 | 5 | 79741081:79741224:79743844:79744223:79745409:79745532 | 79743844:79744223 | ENSG00000039319.12 | ENST00000338008.5,ENST00000510158.1,ENST00000505560.1,ENST00000512558.1 |
| exon_skip_436132 | 5 | 79741081:79741224:79744101:79744223:79745409:79745532 | 79744101:79744223 | ENSG00000039319.12 | ENST00000511829.1 |
| exon_skip_436135 | 5 | 79751510:79751593:79752279:79752384:79752763:79752911 | 79752279:79752384 | ENSG00000039319.12 | ENST00000338008.5,ENST00000510158.1,ENST00000505560.1,ENST00000511829.1 |
| exon_skip_436137 | 5 | 79752763:79752911:79755232:79755313:79768579:79768742 | 79755232:79755313 | ENSG00000039319.12 | ENST00000338008.5,ENST00000510158.1,ENST00000505560.1,ENST00000511829.1,ENST00000512907.1 |
| exon_skip_436140 | 5 | 79755257:79755313:79768579:79768742:79769572:79769678 | 79768579:79768742 | ENSG00000039319.12 | ENST00000338008.5,ENST00000510158.1,ENST00000505560.1,ENST00000511829.1,ENST00000512907.1 |
| exon_skip_436141 | 5 | 79769572:79769678:79770481:79770649:79773037:79773130 | 79770481:79770649 | ENSG00000039319.12 | ENST00000338008.5,ENST00000510158.1,ENST00000505560.1,ENST00000511829.1,ENST00000512907.1,ENST00000513789.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for ZFYVE16 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000510158 | 79707464 | 79707592 | 5UTR-5UTR |
| ENST00000505560 | 79723310 | 79723364 | 5UTR-5UTR |
| ENST00000338008 | 79735754 | 79735851 | Frame-shift |
| ENST00000505560 | 79735754 | 79735851 | Frame-shift |
| ENST00000510158 | 79735754 | 79735851 | Frame-shift |
| ENST00000338008 | 79743844 | 79744223 | Frame-shift |
| ENST00000505560 | 79743844 | 79744223 | Frame-shift |
| ENST00000510158 | 79743844 | 79744223 | Frame-shift |
| ENST00000338008 | 79768579 | 79768742 | Frame-shift |
| ENST00000505560 | 79768579 | 79768742 | Frame-shift |
| ENST00000510158 | 79768579 | 79768742 | Frame-shift |
| ENST00000338008 | 79752279 | 79752384 | In-frame |
| ENST00000505560 | 79752279 | 79752384 | In-frame |
| ENST00000510158 | 79752279 | 79752384 | In-frame |
| ENST00000338008 | 79755232 | 79755313 | In-frame |
| ENST00000505560 | 79755232 | 79755313 | In-frame |
| ENST00000510158 | 79755232 | 79755313 | In-frame |
| ENST00000338008 | 79770481 | 79770649 | In-frame |
| ENST00000505560 | 79770481 | 79770649 | In-frame |
| ENST00000510158 | 79770481 | 79770649 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000510158 | 79707464 | 79707592 | 5UTR-5UTR |
| ENST00000505560 | 79723310 | 79723364 | 5UTR-5UTR |
| ENST00000338008 | 79735754 | 79735851 | Frame-shift |
| ENST00000505560 | 79735754 | 79735851 | Frame-shift |
| ENST00000510158 | 79735754 | 79735851 | Frame-shift |
| ENST00000338008 | 79743844 | 79744223 | Frame-shift |
| ENST00000505560 | 79743844 | 79744223 | Frame-shift |
| ENST00000510158 | 79743844 | 79744223 | Frame-shift |
| ENST00000338008 | 79768579 | 79768742 | Frame-shift |
| ENST00000505560 | 79768579 | 79768742 | Frame-shift |
| ENST00000510158 | 79768579 | 79768742 | Frame-shift |
| ENST00000338008 | 79752279 | 79752384 | In-frame |
| ENST00000505560 | 79752279 | 79752384 | In-frame |
| ENST00000510158 | 79752279 | 79752384 | In-frame |
| ENST00000338008 | 79755232 | 79755313 | In-frame |
| ENST00000505560 | 79755232 | 79755313 | In-frame |
| ENST00000510158 | 79755232 | 79755313 | In-frame |
| ENST00000338008 | 79770481 | 79770649 | In-frame |
| ENST00000505560 | 79770481 | 79770649 | In-frame |
| ENST00000510158 | 79770481 | 79770649 | In-frame |
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Infer the effects of exon skipping event on protein functional features for ZFYVE16 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000338008 | 6790 | 1539 | 79752279 | 79752384 | 3871 | 3975 | 1230 | 1265 |
| ENST00000505560 | 6616 | 1539 | 79752279 | 79752384 | 3912 | 4016 | 1230 | 1265 |
| ENST00000510158 | 6697 | 1539 | 79752279 | 79752384 | 3988 | 4092 | 1230 | 1265 |
| ENST00000338008 | 6790 | 1539 | 79755232 | 79755313 | 4124 | 4204 | 1314 | 1341 |
| ENST00000505560 | 6616 | 1539 | 79755232 | 79755313 | 4165 | 4245 | 1314 | 1341 |
| ENST00000510158 | 6697 | 1539 | 79755232 | 79755313 | 4241 | 4321 | 1314 | 1341 |
| ENST00000338008 | 6790 | 1539 | 79770481 | 79770649 | 4474 | 4641 | 1431 | 1487 |
| ENST00000505560 | 6616 | 1539 | 79770481 | 79770649 | 4515 | 4682 | 1431 | 1487 |
| ENST00000510158 | 6697 | 1539 | 79770481 | 79770649 | 4591 | 4758 | 1431 | 1487 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000338008 | 6790 | 1539 | 79752279 | 79752384 | 3871 | 3975 | 1230 | 1265 |
| ENST00000505560 | 6616 | 1539 | 79752279 | 79752384 | 3912 | 4016 | 1230 | 1265 |
| ENST00000510158 | 6697 | 1539 | 79752279 | 79752384 | 3988 | 4092 | 1230 | 1265 |
| ENST00000338008 | 6790 | 1539 | 79755232 | 79755313 | 4124 | 4204 | 1314 | 1341 |
| ENST00000505560 | 6616 | 1539 | 79755232 | 79755313 | 4165 | 4245 | 1314 | 1341 |
| ENST00000510158 | 6697 | 1539 | 79755232 | 79755313 | 4241 | 4321 | 1314 | 1341 |
| ENST00000338008 | 6790 | 1539 | 79770481 | 79770649 | 4474 | 4641 | 1431 | 1487 |
| ENST00000505560 | 6616 | 1539 | 79770481 | 79770649 | 4515 | 4682 | 1431 | 1487 |
| ENST00000510158 | 6697 | 1539 | 79770481 | 79770649 | 4591 | 4758 | 1431 | 1487 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q7Z3T8 | 1230 | 1265 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1230 | 1265 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1230 | 1265 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1230 | 1265 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1230 | 1265 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1230 | 1265 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1314 | 1341 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1314 | 1341 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1314 | 1341 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1314 | 1341 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1314 | 1341 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1314 | 1341 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1431 | 1487 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1431 | 1487 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1431 | 1487 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1431 | 1487 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1431 | 1487 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1431 | 1487 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q7Z3T8 | 1230 | 1265 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1230 | 1265 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1230 | 1265 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1230 | 1265 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1230 | 1265 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1230 | 1265 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1314 | 1341 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1314 | 1341 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1314 | 1341 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1314 | 1341 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1314 | 1341 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1314 | 1341 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1431 | 1487 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1431 | 1487 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1431 | 1487 | 810 | 1539 | Alternative sequence | ID=VSP_011020;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334 |
| Q7Z3T8 | 1431 | 1487 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1431 | 1487 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
| Q7Z3T8 | 1431 | 1487 | 1 | 1539 | Chain | ID=PRO_0000098716;Note=Zinc finger FYVE domain-containing protein 16 |
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SNVs in the skipped exons for ZFYVE16 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_436121 | 79729928 | 79730036 | 79730020 | 79730020 | Frame_Shift_Del | T | - | p.D18fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_436125 | 79735755 | 79735851 | 79735804 | 79735804 | Frame_Shift_Del | A | - | p.E791fs |
| BRCA | TCGA-E2-A14W-01 | exon_skip_436131 | 79743845 | 79744223 | 79743961 | 79743961 | Frame_Shift_Del | G | - | p.E948fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_436131 | 79743845 | 79744223 | 79744013 | 79744013 | Frame_Shift_Del | T | - | p.F965fs |
| COAD | TCGA-D5-6540-01 | exon_skip_436137 | 79755233 | 79755313 | 79755270 | 79755270 | Frame_Shift_Del | A | - | p.L1327fs |
| STAD | TCGA-B7-5816-01 | exon_skip_436125 | 79735755 | 79735851 | 79735832 | 79735832 | Nonsense_Mutation | C | A | p.C800X |
| PAAD | TCGA-IB-7651-01 | exon_skip_436131 | 79743845 | 79744223 | 79743884 | 79743884 | Nonsense_Mutation | G | T | p.E922* |
| BLCA | TCGA-XF-A8HI-01 | exon_skip_436131 | 79743845 | 79744223 | 79743932 | 79743932 | Nonsense_Mutation | C | T | p.Q938* |
| BLCA | TCGA-ZF-A9RF-01 | exon_skip_436140 | 79768580 | 79768742 | 79768642 | 79768642 | Nonsense_Mutation | C | T | p.Q1363* |
| UCEC | TCGA-D1-A17Q-01 | exon_skip_436140 | 79768580 | 79768742 | 79768693 | 79768693 | Nonsense_Mutation | G | T | p.E1380* |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| HEC6_ENDOMETRIUM | 79752280 | 79752384 | 79752345 | 79752345 | Frame_Shift_Del | A | - | p.G1252fs |
| SNUC4_LARGE_INTESTINE | 79752280 | 79752384 | 79752345 | 79752345 | Frame_Shift_Del | A | - | p.G1252fs |
| IM95_STOMACH | 79755233 | 79755313 | 79755270 | 79755270 | Frame_Shift_Del | A | - | p.L1327fs |
| IGROV1_OVARY | 79743845 | 79744223 | 79743857 | 79743857 | Missense_Mutation | G | A | p.V913M |
| SNU840_OVARY | 79743845 | 79744223 | 79743873 | 79743873 | Missense_Mutation | C | G | p.S918C |
| MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 79743845 | 79744223 | 79743884 | 79743884 | Missense_Mutation | G | A | p.E922K |
| IGR1_SKIN | 79743845 | 79744223 | 79743938 | 79743938 | Missense_Mutation | C | T | p.P940S |
| HS766T_PANCREAS | 79743845 | 79744223 | 79744001 | 79744001 | Missense_Mutation | A | G | p.T961A |
| KMS18_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 79743845 | 79744223 | 79744086 | 79744086 | Missense_Mutation | A | G | p.N989S |
| JHUEM7_ENDOMETRIUM | 79743845 | 79744223 | 79744089 | 79744089 | Missense_Mutation | T | C | p.L990S |
| HEC108_ENDOMETRIUM | 79744102 | 79744223 | 79744176 | 79744176 | Missense_Mutation | A | T | p.E1019V |
| HEC108_ENDOMETRIUM | 79743845 | 79744223 | 79744176 | 79744176 | Missense_Mutation | A | T | p.E1019V |
| SNU1040_LARGE_INTESTINE | 79744102 | 79744223 | 79744177 | 79744177 | Missense_Mutation | G | T | p.E1019D |
| SNU1040_LARGE_INTESTINE | 79743845 | 79744223 | 79744177 | 79744177 | Missense_Mutation | G | T | p.E1019D |
| HS852T_SKIN | 79752280 | 79752384 | 79752331 | 79752331 | Missense_Mutation | C | A | p.H1248N |
| IALM_LUNG | 79752280 | 79752384 | 79752331 | 79752331 | Missense_Mutation | C | A | p.H1248N |
| NCIH1048_LUNG | 79752280 | 79752384 | 79752368 | 79752368 | Missense_Mutation | G | A | p.R1260Q |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 79768580 | 79768742 | 79768615 | 79768615 | Missense_Mutation | A | G | p.N1354D |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 79768580 | 79768742 | 79768617 | 79768617 | Missense_Mutation | T | G | p.N1354K |
| SKMEL30_SKIN | 79768580 | 79768742 | 79768624 | 79768624 | Missense_Mutation | C | T | p.R1357W |
| REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 79768580 | 79768742 | 79768699 | 79768699 | Missense_Mutation | G | A | p.V1382M |
| LU165_LUNG | 79770482 | 79770649 | 79770554 | 79770554 | Missense_Mutation | A | G | p.M1456V |
| RERFLCKJ_LUNG | 79770482 | 79770649 | 79770584 | 79770584 | Missense_Mutation | C | G | p.L1466V |
| TGW_AUTONOMIC_GANGLIA | 79770482 | 79770649 | 79770584 | 79770584 | Missense_Mutation | C | G | p.L1466V |
| FTC238_THYROID | 79770482 | 79770649 | 79770609 | 79770609 | Missense_Mutation | T | C | p.M1474T |
| T47D_BREAST | 79770482 | 79770649 | 79770629 | 79770629 | Missense_Mutation | G | A | p.V1481I |
| CHLA266_SOFT_TISSUE | 79743845 | 79744223 | 79743923 | 79743923 | Nonsense_Mutation | G | T | p.E935* |
| HEYA8_OVARY | 79768580 | 79768742 | 79768636 | 79768636 | Nonsense_Mutation | C | T | p.R1361* |
| HEY_OVARY | 79768580 | 79768742 | 79768636 | 79768636 | Nonsense_Mutation | C | T | p.R1361* |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ZFYVE16 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZFYVE16 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZFYVE16 |
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RelatedDrugs for ZFYVE16 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZFYVE16 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| ZFYVE16 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
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