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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for TBCK |
 Gene summary |
| Gene information | Gene symbol | TBCK | Gene ID | 93627 |
| Gene name | TBC1 domain containing kinase | |
| Synonyms | HSPC302|IHPRF3|TBCKL | |
| Cytomap | 4q24 | |
| Type of gene | protein-coding | |
| Description | TBC domain-containing protein kinase-like protein | |
| Modification date | 20180523 | |
| UniProtAcc | Q8TEA7 | |
| Context | PubMed: TBCK [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for TBCK from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for TBCK |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for TBCK |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_431716 | 4 | 107037475:107037535:107092251:107092427:107114765:107114927 | 107092251:107092427 | ENSG00000145348.12 | ENST00000467183.2,ENST00000394708.2,ENST00000432496.2,ENST00000514689.1,ENST00000510927.1,ENST00000394706.3,ENST00000515705.1,ENST00000361687.4,ENST00000273980.5 |
| exon_skip_431721 | 4 | 107092397:107092427:107114765:107114927:107133906:107133992 | 107114765:107114927 | ENSG00000145348.12 | ENST00000514689.1 |
| exon_skip_431725 | 4 | 107114765:107114927:107115874:107115911:107133906:107133992 | 107115874:107115911 | ENSG00000145348.12 | ENST00000467183.2,ENST00000394708.2,ENST00000432496.2,ENST00000510927.1,ENST00000394706.3,ENST00000515705.1,ENST00000361687.4,ENST00000511011.1,ENST00000273980.5 |
| exon_skip_431726 | 4 | 107151519:107151603:107152885:107152936:107154094:107154221 | 107152885:107152936 | ENSG00000145348.12 | ENST00000467183.2,ENST00000394708.2,ENST00000432496.2,ENST00000510927.1,ENST00000394706.3,ENST00000361687.4,ENST00000273980.5 |
| exon_skip_431727 | 4 | 107154154:107154221:107154744:107154807:107156425:107156524 | 107154744:107154807 | ENSG00000145348.12 | ENST00000467183.2,ENST00000394708.2,ENST00000432496.2,ENST00000510927.1,ENST00000394706.3,ENST00000361687.4,ENST00000503516.1,ENST00000508666.1,ENST00000273980.5 |
| exon_skip_431728 | 4 | 107157915:107157965:107158647:107158695:107163626:107163726 | 107158647:107158695 | ENSG00000145348.12 | ENST00000508666.1 |
| exon_skip_431731 | 4 | 107165841:107165921:107168295:107168444:107171574:107171627 | 107168295:107168444 | ENSG00000145348.12 | ENST00000505574.1 |
| exon_skip_431734 | 4 | 107168295:107168444:107169401:107169463:107170077:107170139 | 107169401:107169463 | ENSG00000145348.12 | ENST00000467183.2,ENST00000394708.2,ENST00000432496.2,ENST00000394706.3,ENST00000361687.4,ENST00000273980.5 |
| exon_skip_431737 | 4 | 107171574:107171635:107172235:107172351:107173022:107173164 | 107172235:107172351 | ENSG00000145348.12 | ENST00000503832.1 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENSG00000145348.12 | ENST00000467183.2,ENST00000506280.1 |
| exon_skip_431740 | 4 | 107181593:107181667:107183254:107183369:107216250:107216323 | 107183254:107183369 | ENSG00000145348.12 | ENST00000467183.2,ENST00000394708.2,ENST00000509532.1,ENST00000432496.2,ENST00000394706.3,ENST00000506280.1,ENST00000273980.5 |
| exon_skip_431742 | 4 | 107229924:107230146:107231083:107231124:107237087:107237392 | 107231083:107231124 | ENSG00000145348.12 | ENST00000507696.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for TBCK |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_431716 | 4 | 107037475:107037535:107092251:107092427:107114765:107114927 | 107092251:107092427 | ENSG00000145348.12 | ENST00000273980.5,ENST00000432496.2,ENST00000510927.1,ENST00000361687.4,ENST00000394706.3,ENST00000467183.2,ENST00000394708.2,ENST00000514689.1,ENST00000515705.1 |
| exon_skip_431721 | 4 | 107092397:107092427:107114765:107114927:107133906:107133992 | 107114765:107114927 | ENSG00000145348.12 | ENST00000514689.1 |
| exon_skip_431725 | 4 | 107114765:107114927:107115874:107115911:107133906:107133992 | 107115874:107115911 | ENSG00000145348.12 | ENST00000273980.5,ENST00000432496.2,ENST00000510927.1,ENST00000361687.4,ENST00000394706.3,ENST00000467183.2,ENST00000394708.2,ENST00000515705.1,ENST00000511011.1 |
| exon_skip_431726 | 4 | 107151519:107151603:107152885:107152936:107154094:107154221 | 107152885:107152936 | ENSG00000145348.12 | ENST00000273980.5,ENST00000432496.2,ENST00000510927.1,ENST00000361687.4,ENST00000394706.3,ENST00000467183.2,ENST00000394708.2 |
| exon_skip_431727 | 4 | 107154154:107154221:107154744:107154807:107156425:107156524 | 107154744:107154807 | ENSG00000145348.12 | ENST00000273980.5,ENST00000432496.2,ENST00000510927.1,ENST00000361687.4,ENST00000394706.3,ENST00000467183.2,ENST00000394708.2,ENST00000508666.1,ENST00000503516.1 |
| exon_skip_431728 | 4 | 107157915:107157965:107158647:107158695:107163626:107163726 | 107158647:107158695 | ENSG00000145348.12 | ENST00000508666.1 |
| exon_skip_431731 | 4 | 107165841:107165921:107168295:107168444:107171574:107171627 | 107168295:107168444 | ENSG00000145348.12 | ENST00000505574.1 |
| exon_skip_431734 | 4 | 107168295:107168444:107169401:107169463:107170077:107170139 | 107169401:107169463 | ENSG00000145348.12 | ENST00000273980.5,ENST00000432496.2,ENST00000361687.4,ENST00000394706.3,ENST00000467183.2,ENST00000394708.2 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENSG00000145348.12 | ENST00000467183.2,ENST00000506280.1 |
| exon_skip_431740 | 4 | 107181593:107181667:107183254:107183369:107216250:107216323 | 107183254:107183369 | ENSG00000145348.12 | ENST00000273980.5,ENST00000432496.2,ENST00000394706.3,ENST00000467183.2,ENST00000394708.2,ENST00000506280.1,ENST00000509532.1 |
| exon_skip_431742 | 4 | 107229924:107230146:107231083:107231124:107237087:107237392 | 107231083:107231124 | ENSG00000145348.12 | ENST00000507696.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for TBCK |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000273980 | 107092251 | 107092427 | Frame-shift |
| ENST00000394708 | 107092251 | 107092427 | Frame-shift |
| ENST00000432496 | 107092251 | 107092427 | Frame-shift |
| ENST00000273980 | 107115874 | 107115911 | Frame-shift |
| ENST00000394708 | 107115874 | 107115911 | Frame-shift |
| ENST00000432496 | 107115874 | 107115911 | Frame-shift |
| ENST00000273980 | 107169401 | 107169463 | Frame-shift |
| ENST00000394708 | 107169401 | 107169463 | Frame-shift |
| ENST00000432496 | 107169401 | 107169463 | Frame-shift |
| ENST00000273980 | 107183254 | 107183369 | Frame-shift |
| ENST00000394708 | 107183254 | 107183369 | Frame-shift |
| ENST00000432496 | 107183254 | 107183369 | Frame-shift |
| ENST00000273980 | 107152885 | 107152936 | In-frame |
| ENST00000394708 | 107152885 | 107152936 | In-frame |
| ENST00000432496 | 107152885 | 107152936 | In-frame |
| ENST00000273980 | 107154744 | 107154807 | In-frame |
| ENST00000394708 | 107154744 | 107154807 | In-frame |
| ENST00000432496 | 107154744 | 107154807 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000273980 | 107092251 | 107092427 | Frame-shift |
| ENST00000394708 | 107092251 | 107092427 | Frame-shift |
| ENST00000432496 | 107092251 | 107092427 | Frame-shift |
| ENST00000273980 | 107115874 | 107115911 | Frame-shift |
| ENST00000394708 | 107115874 | 107115911 | Frame-shift |
| ENST00000432496 | 107115874 | 107115911 | Frame-shift |
| ENST00000273980 | 107169401 | 107169463 | Frame-shift |
| ENST00000394708 | 107169401 | 107169463 | Frame-shift |
| ENST00000432496 | 107169401 | 107169463 | Frame-shift |
| ENST00000273980 | 107183254 | 107183369 | Frame-shift |
| ENST00000394708 | 107183254 | 107183369 | Frame-shift |
| ENST00000432496 | 107183254 | 107183369 | Frame-shift |
| ENST00000273980 | 107152885 | 107152936 | In-frame |
| ENST00000394708 | 107152885 | 107152936 | In-frame |
| ENST00000432496 | 107152885 | 107152936 | In-frame |
| ENST00000273980 | 107154744 | 107154807 | In-frame |
| ENST00000394708 | 107154744 | 107154807 | In-frame |
| ENST00000432496 | 107154744 | 107154807 | In-frame |
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Infer the effects of exon skipping event on protein functional features for TBCK |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000273980 | 8118 | 893 | 107154744 | 107154807 | 1898 | 1960 | 483 | 504 |
| ENST00000394708 | 3064 | 893 | 107154744 | 107154807 | 1815 | 1877 | 483 | 504 |
| ENST00000432496 | 3379 | 893 | 107154744 | 107154807 | 1636 | 1698 | 483 | 504 |
| ENST00000273980 | 8118 | 893 | 107152885 | 107152936 | 2088 | 2138 | 546 | 563 |
| ENST00000394708 | 3064 | 893 | 107152885 | 107152936 | 2005 | 2055 | 546 | 563 |
| ENST00000432496 | 3379 | 893 | 107152885 | 107152936 | 1826 | 1876 | 546 | 563 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000273980 | 8118 | 893 | 107154744 | 107154807 | 1898 | 1960 | 483 | 504 |
| ENST00000394708 | 3064 | 893 | 107154744 | 107154807 | 1815 | 1877 | 483 | 504 |
| ENST00000432496 | 3379 | 893 | 107154744 | 107154807 | 1636 | 1698 | 483 | 504 |
| ENST00000273980 | 8118 | 893 | 107152885 | 107152936 | 2088 | 2138 | 546 | 563 |
| ENST00000394708 | 3064 | 893 | 107152885 | 107152936 | 2005 | 2055 | 546 | 563 |
| ENST00000432496 | 3379 | 893 | 107152885 | 107152936 | 1826 | 1876 | 546 | 563 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for TBCK |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_431716 | 107092252 | 107092427 | 107092289 | 107092289 | Frame_Shift_Del | A | - | p.F733fs |
| HNSC | TCGA-CV-6939-01 | exon_skip_431716 | 107092252 | 107092427 | 107092375 | 107092382 | Frame_Shift_Del | AGTCCAAC | - | p.C702fs |
| HNSC | TCGA-CV-6939-01 | exon_skip_431716 | 107092252 | 107092427 | 107092375 | 107092382 | Frame_Shift_Del | AGTCCAAC | - | p.CWT702fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_431716 | 107092252 | 107092427 | 107092383 | 107092383 | Frame_Shift_Del | A | - | p.C702fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_431716 | 107092252 | 107092427 | 107092383 | 107092383 | Frame_Shift_Del | A | - | p.C702fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_431721 | 107114766 | 107114927 | 107114813 | 107114813 | Frame_Shift_Del | A | - | p.L671fs |
| COAD | TCGA-AY-6197-01 | exon_skip_431725 | 107115875 | 107115911 | 107115874 | 107115874 | Splice_Site | C | T | . |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| CCK81_LARGE_INTESTINE | 107092252 | 107092427 | 107092301 | 107092301 | Missense_Mutation | G | A | p.S729L |
| HCC2998_LARGE_INTESTINE | 107092252 | 107092427 | 107092301 | 107092301 | Missense_Mutation | G | A | p.S729L |
| SNU886_LIVER | 107092252 | 107092427 | 107092319 | 107092319 | Missense_Mutation | C | T | p.S723N |
| SNUC5_LARGE_INTESTINE | 107092252 | 107092427 | 107092320 | 107092320 | Missense_Mutation | T | C | p.S723G |
| NCIH2227_LUNG | 107092252 | 107092427 | 107092418 | 107092418 | Missense_Mutation | A | G | p.I690T |
| HEC251_ENDOMETRIUM | 107114766 | 107114927 | 107114772 | 107114772 | Missense_Mutation | A | C | p.L685V |
| SW756_CERVIX | 107114766 | 107114927 | 107114820 | 107114820 | Missense_Mutation | G | A | p.R669W |
| NCIH250_LUNG | 107114766 | 107114927 | 107114823 | 107114823 | Missense_Mutation | C | A | p.D668Y |
| HS600T_FIBROBLAST | 107114766 | 107114927 | 107114837 | 107114837 | Missense_Mutation | A | G | p.L663P |
| TK_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 107168296 | 107168444 | 107168356 | 107168356 | Missense_Mutation | A | G | p.S291P |
| MDAMB330_BREAST | 107169402 | 107169463 | 107169408 | 107169408 | Missense_Mutation | G | C | p.S259C |
| PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 107183255 | 107183369 | 107183344 | 107183344 | Missense_Mutation | A | T | p.F98I |
| T24_URINARY_TRACT | 107168296 | 107168444 | 107168397 | 107168397 | Nonsense_Mutation | G | T | p.S277* |
| SLR20_KIDNEY | 107168296 | 107168444 | 107168397 | 107168397 | Nonsense_Mutation | G | T | p.S277* |
| ACCS_URINARY_TRACT | 107168296 | 107168444 | 107168397 | 107168397 | Nonsense_Mutation | G | T | p.S277* |
| HCT15_LARGE_INTESTINE | 107154745 | 107154807 | 107154745 | 107154745 | Splice_Site | T | G | p.Q504H |
| HRT18_LARGE_INTESTINE | 107154745 | 107154807 | 107154745 | 107154745 | Splice_Site | T | G | p.Q504H |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for TBCK |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
| exon_skip_431742 | 4 | 107229924:107230146:107231083:107231124:107237087:107237392 | 107231083:107231124 | ENST00000507696.1 | KIRC | rs3109959 | chr4:107231078 | A/G | 5.71e-04 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | BLCA | rs12639869 | chr4:107176104 | C/A | 1.58e-06 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | BLCA | rs12639869 | chr4:107176104 | C/A | 1.58e-06 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | ESCA | rs12639869 | chr4:107176104 | C/A | 1.62e-16 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | HNSC | rs12639869 | chr4:107176104 | C/A | 8.16e-06 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | HNSC | rs12639869 | chr4:107176104 | C/A | 8.16e-06 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | BRCA | rs12639869 | chr4:107176104 | C/A | 7.85e-11 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | BRCA | rs12639869 | chr4:107176104 | C/A | 7.85e-11 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | LAML | rs12639869 | chr4:107176104 | C/A | 6.06e-11 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | KIRP | rs12639869 | chr4:107176104 | C/A | 1.26e-06 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | KIRP | rs12639869 | chr4:107176104 | C/A | 1.26e-06 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | LGG | rs12639869 | chr4:107176104 | C/A | 4.37e-05 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | LGG | rs12639869 | chr4:107176104 | C/A | 4.37e-05 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | KIRC | rs12639869 | chr4:107176104 | C/A | 4.26e-24 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | KIRC | rs12639869 | chr4:107176104 | C/A | 6.94e-06 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | KIRC | rs12639869 | chr4:107176104 | C/A | 1.64e-04 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | LUAD | rs12639869 | chr4:107176104 | C/A | 6.58e-05 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | LUAD | rs12639869 | chr4:107176104 | C/A | 6.58e-05 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | PCPG | rs12639869 | chr4:107176104 | C/A | 7.47e-05 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | PCPG | rs12639869 | chr4:107176104 | C/A | 7.47e-05 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | PRAD | rs12639869 | chr4:107176104 | C/A | 1.88e-06 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | PRAD | rs12639869 | chr4:107176104 | C/A | 1.88e-06 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | SARC | rs12639869 | chr4:107176104 | C/A | 3.14e-04 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | SARC | rs12639869 | chr4:107176104 | C/A | 3.14e-04 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | STAD | rs12639869 | chr4:107176104 | C/A | 8.37e-21 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | THCA | rs12639869 | chr4:107176104 | C/A | 1.00e-08 |
| exon_skip_431738 | 4 | 107173140:107173164:107176103:107176204:107181593:107181667 | 107176103:107176204 | ENST00000467183.2,ENST00000506280.1 | THCA | rs12639869 | chr4:107176104 | C/A | 1.02e-08 |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for TBCK |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for TBCK |
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RelatedDrugs for TBCK |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TBCK |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| TBCK | C4225161 | HYPOTONIA, INFANTILE, WITH PSYCHOMOTOR RETARDATION AND CHARACTERISTIC FACIES 3 | 2 | UNIPROT |
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