ExonSkipDB: functional annotation of exon skipping event in human

Gene summary for ZMYM4

Gene summary

Gene information	Gene symbol	ZMYM4
	Gene ID	9202
	Gene name	zinc finger MYM-type containing 4
	Synonyms	CDIR\|MYM\|ZNF198L3\|ZNF262
	Cytomap	1p34.3
	Type of gene	protein-coding
	Description	zinc finger MYM-type protein 4cell death inhibiting RNAzinc finger protein 262zinc finger, MYM-type 4
	Modification date	20180523
	UniProtAcc	Q5VZL5
	Context	PubMed: ZMYM4 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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Exon skipping events across known transcript of Ensembl for ZMYM4 from UCSC genome browser

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Gene isoform structures and expression levels for ZMYM4

Expression levels of gene isoforms across TCGA.

Expression levels of gene isoforms across GTEx.

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Exon skipping events with PSIs in TCGA for ZMYM4

Information of exkip skipping event in TCGA.

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_4155	1	35734633:35734686:35761527:35761589:35790960:35791006	35761527:35761589	ENSG00000146463.7	ENST00000441447.1
exon_skip_4158	1	35734633:35734686:35790960:35791006:35824525:35824830	35790960:35791006	ENSG00000146463.7	ENST00000373297.2
exon_skip_4177	1	35761527:35761589:35790960:35791006:35824525:35824830	35790960:35791006	ENSG00000146463.7	ENST00000441447.1
exon_skip_4182	1	35826794:35826856:35827219:35827390:35835629:35835714	35827219:35827390	ENSG00000146463.7	ENST00000373297.2,ENST00000314607.6
exon_skip_4185	1	35835629:35835714:35835972:35836228:35846859:35847034	35835972:35836228	ENSG00000146463.7	ENST00000457946.1,ENST00000373297.2,ENST00000314607.6
exon_skip_4186	1	35846859:35847034:35847146:35847359:35851042:35851193	35847146:35847359	ENSG00000146463.7	ENST00000314607.6
exon_skip_4187	1	35852603:35852879:35853054:35853205:35854510:35854683	35853054:35853205	ENSG00000146463.7	ENST00000457946.1,ENST00000373297.2,ENST00000314607.6
exon_skip_4190	1	35853054:35853205:35854510:35854683:35855548:35855699	35854510:35854683	ENSG00000146463.7	ENST00000457946.1,ENST00000373297.2,ENST00000314607.6
exon_skip_4192	1	35855548:35855699:35857812:35857953:35858247:35858285	35857812:35857953	ENSG00000146463.7	ENST00000457946.1,ENST00000373297.2,ENST00000314607.6
exon_skip_4195	1	35862155:35862271:35862652:35862724:35862977:35863063	35862652:35862724	ENSG00000146463.7	ENST00000470175.1
exon_skip_4196	1	35864464:35864644:35865082:35865177:35870623:35870795	35865082:35865177	ENSG00000146463.7	ENST00000457946.1,ENST00000373297.2,ENST00000314607.6
exon_skip_4199	1	35870973:35871069:35873608:35873760:35879572:35879684	35873608:35873760	ENSG00000146463.7	ENST00000457946.1,ENST00000373297.2,ENST00000314607.6
exon_skip_4204	1	35873608:35873760:35879572:35879684:35881066:35881315	35879572:35879684	ENSG00000146463.7	ENST00000457946.1,ENST00000373297.2,ENST00000314607.6
exon_skip_4205	1	35881066:35881315:35884043:35884173:35885070:35887544	35884043:35884173	ENSG00000146463.7	ENST00000457946.1,ENST00000373297.2,ENST00000314607.6

PSI values of skipped exons in TCGA.

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Exon skipping events with PSIs in GTEx for ZMYM4

Information of exkip skipping event in GTEx

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_4155	1	35734633:35734686:35761527:35761589:35790960:35791006	35761527:35761589	ENSG00000146463.7	ENST00000441447.1
exon_skip_4158	1	35734633:35734686:35790960:35791006:35824525:35824830	35790960:35791006	ENSG00000146463.7	ENST00000373297.2
exon_skip_4177	1	35761527:35761589:35790960:35791006:35824525:35824830	35790960:35791006	ENSG00000146463.7	ENST00000441447.1
exon_skip_4182	1	35826794:35826856:35827219:35827390:35835629:35835714	35827219:35827390	ENSG00000146463.7	ENST00000314607.6,ENST00000373297.2
exon_skip_4185	1	35835629:35835714:35835972:35836228:35846859:35847034	35835972:35836228	ENSG00000146463.7	ENST00000314607.6,ENST00000373297.2,ENST00000457946.1
exon_skip_4186	1	35846859:35847034:35847146:35847359:35851042:35851193	35847146:35847359	ENSG00000146463.7	ENST00000314607.6
exon_skip_4187	1	35852603:35852879:35853054:35853205:35854510:35854683	35853054:35853205	ENSG00000146463.7	ENST00000314607.6,ENST00000373297.2,ENST00000457946.1
exon_skip_4190	1	35853054:35853205:35854510:35854683:35855548:35855699	35854510:35854683	ENSG00000146463.7	ENST00000314607.6,ENST00000373297.2,ENST00000457946.1
exon_skip_4192	1	35855548:35855699:35857812:35857953:35858247:35858285	35857812:35857953	ENSG00000146463.7	ENST00000314607.6,ENST00000373297.2,ENST00000457946.1
exon_skip_4195	1	35862155:35862271:35862652:35862724:35862977:35863063	35862652:35862724	ENSG00000146463.7	ENST00000470175.1
exon_skip_4196	1	35864464:35864644:35865082:35865177:35870623:35870795	35865082:35865177	ENSG00000146463.7	ENST00000314607.6,ENST00000373297.2,ENST00000457946.1
exon_skip_4199	1	35870973:35871069:35873608:35873760:35879572:35879684	35873608:35873760	ENSG00000146463.7	ENST00000314607.6,ENST00000373297.2,ENST00000457946.1
exon_skip_4204	1	35873608:35873760:35879572:35879684:35881066:35881315	35879572:35879684	ENSG00000146463.7	ENST00000314607.6,ENST00000373297.2,ENST00000457946.1
exon_skip_4205	1	35881066:35881315:35884043:35884173:35885070:35887544	35884043:35884173	ENSG00000146463.7	ENST00000314607.6,ENST00000373297.2,ENST00000457946.1

PSI values of skipped exons in GTEx.

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for ZMYM4

Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000314607	35835972	35836228	Frame-shift
ENST00000314607	35853054	35853205	Frame-shift
ENST00000314607	35854510	35854683	Frame-shift
ENST00000314607	35865082	35865177	Frame-shift
ENST00000314607	35873608	35873760	Frame-shift
ENST00000314607	35879572	35879684	Frame-shift
ENST00000314607	35884043	35884173	Frame-shift
ENST00000314607	35827219	35827390	In-frame
ENST00000314607	35847146	35847359	In-frame
ENST00000314607	35857812	35857953	In-frame

Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000314607	35835972	35836228	Frame-shift
ENST00000314607	35853054	35853205	Frame-shift
ENST00000314607	35854510	35854683	Frame-shift
ENST00000314607	35865082	35865177	Frame-shift
ENST00000314607	35873608	35873760	Frame-shift
ENST00000314607	35879572	35879684	Frame-shift
ENST00000314607	35884043	35884173	Frame-shift
ENST00000314607	35827219	35827390	In-frame
ENST00000314607	35847146	35847359	In-frame
ENST00000314607	35857812	35857953	In-frame

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Infer the effects of exon skipping event on protein functional features for ZMYM4

Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.

Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000314607	7011	1548	35827219	35827390	750	920	223	280
ENST00000314607	7011	1548	35847146	35847359	1437	1649	452	523
ENST00000314607	7011	1548	35857812	35857953	2668	2808	862	909

Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000314607	7011	1548	35827219	35827390	750	920	223	280
ENST00000314607	7011	1548	35847146	35847359	1437	1649	452	523
ENST00000314607	7011	1548	35857812	35857953	2668	2808	862	909

Lost protein functional features of individual exon skipping events in TCGA.

UniProt acc.	Start of exon skipping (AA)	End of exon skipping (AA)	Protein feature start (AA)	Protein feature end (AA)	Category of protein feature	Description of feature
Q5VZL5	223	280	1	324	Alternative sequence	ID=VSP_027512;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303\|PubMed:15489334;Dbxref=PMID:15489334
Q5VZL5	223	280	2	1548	Chain	ID=PRO_0000299017;Note=Zinc finger MYM-type protein 4
Q5VZL5	223	280	232	232	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:28112733;Dbxref=PMID:28112733
Q5VZL5	223	280	250	250	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)%3B alternate;Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:25114211;Dbxref=PMID:25114211
Q5VZL5	223	280	250	250	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)%3B alternate;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244\|PubMed:25114211,ECO:0000244\|PubMed:25218447,ECO:0000244\|PubMed:25755297,E
Q5VZL5	223	280	260	260	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:28112733;Dbxref=PMID:28112733
Q5VZL5	223	280	271	271	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:28112733;Dbxref=PMID:28112733
Q5VZL5	223	280	273	273	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244\|PubMed:25114211,ECO:0000244\|PubMed:25218447,ECO:0000244\|PubMed:25755297,ECO:0000244\|Pu
Q5VZL5	223	280	242	242	Modified residue	Note=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:23186163;Dbxref=PMID:23186163
Q5VZL5	223	280	279	280	Sequence conflict	Note=AQ->RT;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q5VZL5	452	523	2	1548	Chain	ID=PRO_0000299017;Note=Zinc finger MYM-type protein 4
Q5VZL5	452	523	452	452	Natural variant	ID=VAR_034764;Note=V->I;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:9455477;Dbxref=dbSNP:rs34924462,PMID:9455477
Q5VZL5	452	523	414	457	Zinc finger	Note=MYM-type 2
Q5VZL5	452	523	464	499	Zinc finger	Note=MYM-type 3
Q5VZL5	452	523	510	544	Zinc finger	Note=MYM-type 4
Q5VZL5	862	909	2	1548	Chain	ID=PRO_0000299017;Note=Zinc finger MYM-type protein 4

Lost protein functional features of individual exon skipping events in GTEx.

UniProt acc.	Start of exon skipping (AA)	End of exon skipping (AA)	Protein feature start (AA)	Protein feature end (AA)	Category of protein feature	Description of feature
Q5VZL5	223	280	1	324	Alternative sequence	ID=VSP_027512;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303\|PubMed:15489334;Dbxref=PMID:15489334
Q5VZL5	223	280	2	1548	Chain	ID=PRO_0000299017;Note=Zinc finger MYM-type protein 4
Q5VZL5	223	280	232	232	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:28112733;Dbxref=PMID:28112733
Q5VZL5	223	280	250	250	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)%3B alternate;Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:25114211;Dbxref=PMID:25114211
Q5VZL5	223	280	250	250	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)%3B alternate;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244\|PubMed:25114211,ECO:0000244\|PubMed:25218447,ECO:0000244\|PubMed:25755297,E
Q5VZL5	223	280	260	260	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:28112733;Dbxref=PMID:28112733
Q5VZL5	223	280	271	271	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:28112733;Dbxref=PMID:28112733
Q5VZL5	223	280	273	273	Cross-link	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244\|PubMed:25114211,ECO:0000244\|PubMed:25218447,ECO:0000244\|PubMed:25755297,ECO:0000244\|Pu
Q5VZL5	223	280	242	242	Modified residue	Note=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:23186163;Dbxref=PMID:23186163
Q5VZL5	223	280	279	280	Sequence conflict	Note=AQ->RT;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q5VZL5	452	523	2	1548	Chain	ID=PRO_0000299017;Note=Zinc finger MYM-type protein 4
Q5VZL5	452	523	452	452	Natural variant	ID=VAR_034764;Note=V->I;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:9455477;Dbxref=dbSNP:rs34924462,PMID:9455477
Q5VZL5	452	523	414	457	Zinc finger	Note=MYM-type 2
Q5VZL5	452	523	464	499	Zinc finger	Note=MYM-type 3
Q5VZL5	452	523	510	544	Zinc finger	Note=MYM-type 4
Q5VZL5	862	909	2	1548	Chain	ID=PRO_0000299017;Note=Zinc finger MYM-type protein 4

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SNVs in the skipped exons for ZMYM4

- Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.

- Differential PSIs between mutated versus non-mutated samples.

- Non-synonymous mutations located in the skipped exons in TCGA.

Cancer type	Sample	ESID	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
LIHC	TCGA-DD-A39Y-01	exon_skip_4158 exon_skip_4177	35790961	35791006	35790968	35790968	Frame_Shift_Del	A	-	p.Q16fs
LIHC	TCGA-DD-A1EG-01	exon_skip_4185	35835973	35836228	35836080	35836080	Frame_Shift_Del	A	-	p.K346fs
LIHC	TCGA-DD-A39Y-01	exon_skip_4185	35835973	35836228	35836080	35836080	Frame_Shift_Del	A	-	p.K346fs
STAD	TCGA-BR-4368-01	exon_skip_4185	35835973	35836228	35836080	35836080	Frame_Shift_Del	A	-	p.C344fs
STAD	TCGA-CG-5721-01	exon_skip_4185	35835973	35836228	35836080	35836080	Frame_Shift_Del	A	-	p.C344fs
STAD	TCGA-CG-5726-01	exon_skip_4185	35835973	35836228	35836080	35836080	Frame_Shift_Del	A	-	p.C344fs
UCEC	TCGA-D1-A17B-01	exon_skip_4185	35835973	35836228	35836080	35836080	Frame_Shift_Del	A	-	p.K345fs
LIHC	TCGA-G3-A3CJ-01	exon_skip_4186	35847147	35847359	35847276	35847276	Frame_Shift_Del	G	-	p.G496fs
LIHC	TCGA-DD-A39Y-01	exon_skip_4192	35857813	35857953	35857848	35857848	Frame_Shift_Del	C	-	p.P876fs
LIHC	TCGA-BC-A3KG-01	exon_skip_4192	35857813	35857953	35857862	35857862	Frame_Shift_Del	A	-	p.R879fs
LIHC	TCGA-DD-A1EG-01	exon_skip_4199	35873609	35873760	35873649	35873649	Frame_Shift_Del	T	-	p.T1279fs
UCEC	TCGA-B5-A0K6-01	exon_skip_4199	35873609	35873760	35873711	35873711	Frame_Shift_Del	A	-	p.E1300fs
STAD	TCGA-B7-A5TJ-01	exon_skip_4205	35884044	35884173	35884071	35884075	Frame_Shift_Del	GAAAT	-	p.1446_1447del
STAD	TCGA-B7-A5TJ-01	exon_skip_4205	35884044	35884173	35884071	35884075	Frame_Shift_Del	GAAAT	-	p.RN1446fs
LIHC	TCGA-BC-A112-01	exon_skip_4185	35835973	35836228	35835980	35835981	Frame_Shift_Ins	-	T	p.D312fs
STAD	TCGA-CD-A4MG-01	exon_skip_4185	35835973	35836228	35836079	35836080	Frame_Shift_Ins	-	A	p.C344fs
STAD	TCGA-CG-4305-01	exon_skip_4185	35835973	35836228	35836079	35836080	Frame_Shift_Ins	-	A	p.C344fs
STAD	TCGA-CD-A4MG-01	exon_skip_4185	35835973	35836228	35836080	35836081	Frame_Shift_Ins	-	A	p.C344fs
STAD	TCGA-CG-4305-01	exon_skip_4185	35835973	35836228	35836080	35836081	Frame_Shift_Ins	-	A	p.C344fs
COAD	TCGA-D5-6928-01	exon_skip_4190	35854511	35854683	35854659	35854660	Frame_Shift_Ins	-	A	p.S804fs
KIRC	TCGA-CZ-5470-01	exon_skip_4158 exon_skip_4177	35790961	35791006	35790967	35790967	Nonsense_Mutation	C	T	p.Q16X
KIRC	TCGA-AS-3778-01	exon_skip_4185	35835973	35836228	35836039	35836039	Nonsense_Mutation	C	A	p.S331*
KIRC	TCGA-AS-3778-01	exon_skip_4185	35835973	35836228	35836039	35836039	Nonsense_Mutation	C	A	p.S331X
UCS	TCGA-ND-A4WC-01	exon_skip_4185	35835973	35836228	35836059	35836059	Nonsense_Mutation	C	T	p.R338*
UCS	TCGA-ND-A4WC-01	exon_skip_4185	35835973	35836228	35836059	35836059	Nonsense_Mutation	C	T	p.R338X
UCEC	TCGA-A5-A0G5-01	exon_skip_4185	35835973	35836228	35836101	35836101	Nonsense_Mutation	C	T	p.Q352*
BLCA	TCGA-CU-A3QU-01	exon_skip_4187	35853055	35853205	35853067	35853067	Nonsense_Mutation	C	T	p.Q709*
SKCM	TCGA-EB-A299-01	exon_skip_4187	35853055	35853205	35853067	35853067	Nonsense_Mutation	C	T	p.Q709*

- Depth of coverage in the three exons composing exon skipping event

Depth of coverage in three exons

Mutation description

- Non-synonymous mutations located in the skipped exons in CCLE.

Sample	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
LS180_LARGE_INTESTINE	35790961	35791006	35790968	35790968	Frame_Shift_Del	A	-	p.Q16fs
LOVO_LARGE_INTESTINE	35835973	35836228	35836080	35836080	Frame_Shift_Del	A	-	p.K346fs
TUHR10TKB_KIDNEY	35873609	35873760	35873678	35873680	In_Frame_Del	AGT	-	p.1289_1290QF>L
BICR18_UPPER_AERODIGESTIVE_TRACT	35790961	35791006	35790977	35790977	Missense_Mutation	G	A	p.G19D
HT115_LARGE_INTESTINE	35790961	35791006	35791002	35791002	Missense_Mutation	G	T	p.E27D
BICR18_UPPER_AERODIGESTIVE_TRACT	35827220	35827390	35827242	35827242	Missense_Mutation	A	G	p.N231S
DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	35827220	35827390	35827242	35827242	Missense_Mutation	A	G	p.N231S
CALU1_LUNG	35827220	35827390	35827269	35827269	Missense_Mutation	G	C	p.G240A
MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	35827220	35827390	35827320	35827320	Missense_Mutation	A	C	p.E257A
JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	35827220	35827390	35827322	35827322	Missense_Mutation	T	C	p.Y258H
KP2_PANCREAS	35835973	35836228	35836009	35836009	Missense_Mutation	C	T	p.A321V
JHUEM2_ENDOMETRIUM	35835973	35836228	35836080	35836080	Missense_Mutation	A	G	p.K345E
UACC812_BREAST	35835973	35836228	35836212	35836212	Missense_Mutation	T	C	p.C389R
HCT15_LARGE_INTESTINE	35847147	35847359	35847192	35847192	Missense_Mutation	A	G	p.S468G
CW2_LARGE_INTESTINE	35847147	35847359	35847201	35847201	Missense_Mutation	T	C	p.C471R
UMUC5_URINARY_TRACT	35847147	35847359	35847208	35847208	Missense_Mutation	C	G	p.S473C
BICR18_UPPER_AERODIGESTIVE_TRACT	35853055	35853205	35853089	35853089	Missense_Mutation	C	G	p.S716C
DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	35854511	35854683	35854541	35854541	Missense_Mutation	C	G	p.A765G
BICR18_UPPER_AERODIGESTIVE_TRACT	35854511	35854683	35854541	35854541	Missense_Mutation	C	G	p.A765G
DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	35854511	35854683	35854556	35854556	Missense_Mutation	A	G	p.N770S
CW2_LARGE_INTESTINE	35854511	35854683	35854651	35854651	Missense_Mutation	T	C	p.C802R
KYSE410_OESOPHAGUS	35873609	35873760	35873648	35873648	Missense_Mutation	C	G	p.T1279S
DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	35873609	35873760	35873653	35873653	Missense_Mutation	G	T	p.A1281S
BICR18_UPPER_AERODIGESTIVE_TRACT	35873609	35873760	35873653	35873653	Missense_Mutation	G	T	p.A1281S
NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	35873609	35873760	35873696	35873696	Missense_Mutation	G	A	p.R1295Q
TE10_OESOPHAGUS	35873609	35873760	35873702	35873702	Missense_Mutation	C	T	p.P1297L
BALL1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	35873609	35873760	35873707	35873707	Missense_Mutation	G	C	p.G1299R
MCC13_SKIN	35873609	35873760	35873722	35873723	Missense_Mutation	CC	TT	p.P1304L
MCC13_SKIN	35873609	35873760	35873722	35873722	Missense_Mutation	C	T	p.P1304S
MCC13_SKIN	35873609	35873760	35873723	35873723	Missense_Mutation	C	T	p.P1304L
MOLT3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	35879573	35879684	35879589	35879589	Missense_Mutation	G	A	p.G1322D
HS940T_FIBROBLAST	35879573	35879684	35879632	35879632	Missense_Mutation	G	T	p.M1336I
SBC1_LUNG	35879573	35879684	35879659	35879659	Missense_Mutation	A	G	p.I1345M
PACADD137_PANCREAS	35884044	35884173	35884104	35884104	Missense_Mutation	A	G	p.E1457G
MCC26_SKIN	35884044	35884173	35884171	35884171	Missense_Mutation	A	T	p.K1479N
SNU81_LARGE_INTESTINE	35827220	35827390	35827247	35827247	Nonsense_Mutation	G	T	p.E233*

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ZMYM4

sQTL information located at the skipped exons.

Exon skip ID

Chromosome

Three exons

Skippped exon

ENST

Cancer type

SNP id

Location

DNA change (ref/var)

P-value

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZMYM4

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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZMYM4

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RelatedDrugs for ZMYM4

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for ZMYM4

Diseases associated with this gene.
(DisGeNet 4.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	Gene structures and expression levels
	Exon skipping events with PSIs in TCGA
	Exon skipping events with PSIs in GTEx
	Open reading frame (ORF) annotation in the exon skipping event
	Exon skipping events in the canonical protein sequence
	SNVs in the skipped exons with depth of coverage
	Splicing Quantitative Trait Loci (sQTLs) in the skipped exons
	Splicing Quantitative Trait Methylation (sQTM) in the skipped exon
	Related drugs with this gene
	Related diseases with this gene

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Gene summary for ZMYM4

Exon skipping events across known transcript of Ensembl for ZMYM4 from UCSC genome browser

Gene isoform structures and expression levels for ZMYM4

Exon skipping events with PSIs in TCGA for ZMYM4

Exon skipping events with PSIs in GTEx for ZMYM4

Open reading frame (ORF) annotation in the exon skipping event for ZMYM4

Infer the effects of exon skipping event on protein functional features for ZMYM4

SNVs in the skipped exons for ZMYM4

Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ZMYM4

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZMYM4

Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZMYM4

RelatedDrugs for ZMYM4

RelatedDiseases for ZMYM4