ExonSkipDB: functional annotation of exon skipping event in human

Gene summary for SLC16A5

Gene summary

Gene information	Gene symbol	SLC16A5
	Gene ID	9121
	Gene name	solute carrier family 16 member 5
	Synonyms	MCT5\|MCT6
	Cytomap	17q25.1
	Type of gene	protein-coding
	Description	monocarboxylate transporter 6monocarboxylate transporter 5solute carrier family 16 (monocarboxylate transporter), member 5solute carrier family 16 (monocarboxylic acid transporters), member 5solute carrier family 16, member 5 (monocarboxylic acid tran
	Modification date	20180523
	UniProtAcc	O15375
	Context	PubMed: SLC16A5 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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Exon skipping events across known transcript of Ensembl for SLC16A5 from UCSC genome browser

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Gene isoform structures and expression levels for SLC16A5

Expression levels of gene isoforms across TCGA.

Expression levels of gene isoforms across GTEx.

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Exon skipping events with PSIs in TCGA for SLC16A5

Information of exkip skipping event in TCGA.

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_155902	17	73083828:73083991:73085208:73085399:73089683:73089891	73085208:73085399	ENSG00000170190.11	ENST00000578847.1
exon_skip_155908	17	73084059:73084139:73085208:73085399:73089683:73089891	73085208:73085399	ENSG00000170190.11	ENST00000578376.1
exon_skip_155910	17	73084059:73084139:73085245:73085399:73089683:73089891	73085245:73085399	ENSG00000170190.11	ENST00000585293.1,ENST00000329783.4
exon_skip_155916	17	73085245:73085399:73089683:73089930:73094132:73094276	73089683:73089930	ENSG00000170190.11	ENST00000585293.1,ENST00000578376.1,ENST00000450736.2,ENST00000580123.1,ENST00000329783.4
exon_skip_155918	17	73089683:73089930:73094132:73094276:73096101:73096277	73094132:73094276	ENSG00000170190.11	ENST00000578376.1,ENST00000450736.2,ENST00000584118.1,ENST00000584207.1,ENST00000580123.1,ENST00000538213.2,ENST00000329783.4
exon_skip_155930	17	73094132:73094276:73096101:73096911:73100064:73100275	73096101:73096911	ENSG00000170190.11	ENST00000578376.1,ENST00000450736.2,ENST00000580123.1,ENST00000538213.2,ENST00000329783.4

PSI values of skipped exons in TCGA.

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Exon skipping events with PSIs in GTEx for SLC16A5

Information of exkip skipping event in GTEx

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_155902	17	73083828:73083991:73085208:73085399:73089683:73089891	73085208:73085399	ENSG00000170190.11	ENST00000578847.1
exon_skip_155908	17	73084059:73084139:73085208:73085399:73089683:73089891	73085208:73085399	ENSG00000170190.11	ENST00000578376.1
exon_skip_155910	17	73084059:73084139:73085245:73085399:73089683:73089891	73085245:73085399	ENSG00000170190.11	ENST00000585293.1,ENST00000329783.4
exon_skip_155916	17	73085245:73085399:73089683:73089930:73094132:73094276	73089683:73089930	ENSG00000170190.11	ENST00000580123.1,ENST00000585293.1,ENST00000578376.1,ENST00000329783.4,ENST00000450736.2
exon_skip_155918	17	73089683:73089930:73094132:73094276:73096101:73096277	73094132:73094276	ENSG00000170190.11	ENST00000580123.1,ENST00000578376.1,ENST00000329783.4,ENST00000450736.2,ENST00000584207.1,ENST00000538213.2,ENST00000584118.1
exon_skip_155930	17	73094132:73094276:73096101:73096911:73100064:73100275	73096101:73096911	ENSG00000170190.11	ENST00000580123.1,ENST00000578376.1,ENST00000329783.4,ENST00000450736.2,ENST00000538213.2

PSI values of skipped exons in GTEx.

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for SLC16A5

Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000329783	73089683	73089930	5CDS-5UTR
ENST00000450736	73089683	73089930	5CDS-5UTR
ENST00000580123	73089683	73089930	5CDS-5UTR
ENST00000329783	73085245	73085399	5UTR-5UTR
ENST00000329783	73094132	73094276	In-frame
ENST00000450736	73094132	73094276	In-frame
ENST00000580123	73094132	73094276	In-frame
ENST00000329783	73096101	73096911	In-frame
ENST00000450736	73096101	73096911	In-frame
ENST00000580123	73096101	73096911	In-frame

Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000329783	73089683	73089930	5CDS-5UTR
ENST00000450736	73089683	73089930	5CDS-5UTR
ENST00000580123	73089683	73089930	5CDS-5UTR
ENST00000329783	73085245	73085399	5UTR-5UTR
ENST00000329783	73094132	73094276	In-frame
ENST00000450736	73094132	73094276	In-frame
ENST00000580123	73094132	73094276	In-frame
ENST00000329783	73096101	73096911	In-frame
ENST00000450736	73096101	73096911	In-frame
ENST00000580123	73096101	73096911	In-frame

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Infer the effects of exon skipping event on protein functional features for SLC16A5

Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.

Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000329783	1951	505	73094132	73094276	487	630	66	114
ENST00000450736	2068	505	73094132	73094276	615	758	66	114
ENST00000580123	2036	505	73094132	73094276	572	715	66	114
ENST00000329783	1951	505	73096101	73096911	631	1440	114	384
ENST00000450736	2068	505	73096101	73096911	759	1568	114	384
ENST00000580123	2036	505	73096101	73096911	716	1525	114	384

Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000329783	1951	505	73094132	73094276	487	630	66	114
ENST00000450736	2068	505	73094132	73094276	615	758	66	114
ENST00000580123	2036	505	73094132	73094276	572	715	66	114
ENST00000329783	1951	505	73096101	73096911	631	1440	114	384
ENST00000450736	2068	505	73096101	73096911	759	1568	114	384
ENST00000580123	2036	505	73096101	73096911	716	1525	114	384

Lost protein functional features of individual exon skipping events in TCGA.

UniProt acc.	Start of exon skipping (AA)	End of exon skipping (AA)	Protein feature start (AA)	Protein feature end (AA)	Category of protein feature	Description of feature
O15375	66	114	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	66	114	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	66	114	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	66	114	75	80	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	75	80	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	75	80	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	102	110	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	102	110	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	102	110	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	54	74	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	54	74	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	54	74	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	81	101	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	81	101	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	81	101	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	114	384	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	114	384	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	114	384	132	137	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	132	137	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	132	137	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	159	171	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	159	171	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	159	171	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	193	239	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	193	239	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	193	239	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	261	274	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	261	274	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	261	274	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	296	305	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	296	305	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	296	305	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	327	329	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	327	329	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	327	329	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	351	367	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	351	367	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	351	367	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	138	158	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	138	158	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	138	158	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	172	192	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	172	192	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	172	192	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	240	260	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	240	260	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	240	260	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	275	295	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	275	295	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	275	295	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	306	326	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	306	326	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	306	326	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	330	350	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	330	350	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	330	350	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	368	388	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	368	388	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	368	388	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255

Lost protein functional features of individual exon skipping events in GTEx.

UniProt acc.	Start of exon skipping (AA)	End of exon skipping (AA)	Protein feature start (AA)	Protein feature end (AA)	Category of protein feature	Description of feature
O15375	66	114	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	66	114	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	66	114	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	66	114	75	80	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	75	80	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	75	80	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	102	110	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	102	110	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	102	110	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	54	74	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	54	74	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	54	74	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	81	101	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	81	101	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	81	101	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	66	114	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	114	384	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	114	384	1	505	Chain	ID=PRO_0000211399;Note=Monocarboxylate transporter 6
O15375	114	384	132	137	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	132	137	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	132	137	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	159	171	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	159	171	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	159	171	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	193	239	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	193	239	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	193	239	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	261	274	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	261	274	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	261	274	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	296	305	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	296	305	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	296	305	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	327	329	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	327	329	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	327	329	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	351	367	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	351	367	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	351	367	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	111	131	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	138	158	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	138	158	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	138	158	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	172	192	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	172	192	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	172	192	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	240	260	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	240	260	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	240	260	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	275	295	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	275	295	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	275	295	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	306	326	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	306	326	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	306	326	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	330	350	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	330	350	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	330	350	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	368	388	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	368	388	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15375	114	384	368	388	Transmembrane	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255

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SNVs in the skipped exons for SLC16A5

- Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.

- Differential PSIs between mutated versus non-mutated samples.

- Non-synonymous mutations located in the skipped exons in TCGA.

Cancer type	Sample	ESID	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
HNSC	TCGA-CN-A63T-01	exon_skip_155916	73089684	73089930	73089780	73089780	Frame_Shift_Del	C	-	p.L18fs
LIHC	TCGA-DD-A3A0-01	exon_skip_155918	73094133	73094276	73094135	73094135	Frame_Shift_Del	C	-	p.G67fs
LIHC	TCGA-DD-A3A0-01	exon_skip_155918	73094133	73094276	73094135	73094135	Frame_Shift_Del	C	-	p.P68fs
STAD	TCGA-BR-4292-01	exon_skip_155918	73094133	73094276	73094188	73094188	Frame_Shift_Del	G	-	p.L85fs
LIHC	TCGA-DD-A3A0-01	exon_skip_155930	73096102	73096911	73096234	73096234	Frame_Shift_Del	C	-	p.S159fs
LIHC	TCGA-DD-A3A0-01	exon_skip_155930	73096102	73096911	73096579	73096579	Frame_Shift_Del	C	-	p.A274fs
LIHC	TCGA-BC-A3KG-01	exon_skip_155930	73096102	73096911	73096623	73096623	Frame_Shift_Del	C	-	p.P289fs
LIHC	TCGA-DD-A1EG-01	exon_skip_155930	73096102	73096911	73096656	73096656	Frame_Shift_Del	T	-	p.F300fs
STAD	TCGA-CG-5721-01	exon_skip_155930	73096102	73096911	73096719	73096720	Frame_Shift_Del	GT	-	p.L320fs
UCS	TCGA-ND-A4W6-01	exon_skip_155930	73096102	73096911	73096839	73096839	Nonsense_Mutation	C	T	p.Q361*
UCS	TCGA-ND-A4W6-01	exon_skip_155930	73096102	73096911	73096839	73096839	Nonsense_Mutation	C	T	p.Q361X
UCEC	TCGA-BS-A0UF-01	exon_skip_155916	73089684	73089930	73089932	73089932	Splice_Site	T	G	e1+2

- Depth of coverage in the three exons composing exon skipping event

Depth of coverage in three exons

Mutation description

- Non-synonymous mutations located in the skipped exons in CCLE.

Sample	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
CORL279_LUNG	73089684	73089930	73089895	73089896	Frame_Shift_Ins	-	CCCCTCC	p.-56fs
SNUC2A_LARGE_INTESTINE	73089684	73089930	73089826	73089826	Missense_Mutation	C	T	p.T32M
SNUC2B_LARGE_INTESTINE	73089684	73089930	73089826	73089826	Missense_Mutation	C	T	p.T32M
HCC2998_LARGE_INTESTINE	73089684	73089930	73089835	73089835	Missense_Mutation	G	A	p.G35D
MDAMB453_BREAST	73089684	73089930	73089889	73089889	Missense_Mutation	C	G	p.S53C
KARPAS45_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	73094133	73094276	73094142	73094142	Missense_Mutation	G	A	p.C70Y
RCCFG2_KIDNEY	73094133	73094276	73094157	73094157	Missense_Mutation	G	A	p.G75E
COLO668_LUNG	73096102	73096911	73096223	73096223	Missense_Mutation	G	T	p.W155C
JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	73096102	73096911	73096237	73096237	Missense_Mutation	G	A	p.R160H
MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	73096102	73096911	73096237	73096237	Missense_Mutation	G	A	p.R160H
JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	73096102	73096911	73096284	73096284	Missense_Mutation	G	A	p.G176S
TE8_OESOPHAGUS	73096102	73096911	73096308	73096308	Missense_Mutation	A	C	p.I184L
LNCAPCLONEFGC_PROSTATE	73096102	73096911	73096330	73096330	Missense_Mutation	C	A	p.P191H
HEC6_ENDOMETRIUM	73096102	73096911	73096335	73096335	Missense_Mutation	G	A	p.A193T
SW962_VULVA	73096102	73096911	73096383	73096383	Missense_Mutation	G	A	p.E209K
ISHIKAWAHERAKLIO02ER_ENDOMETRIUM	73096102	73096911	73096484	73096484	Missense_Mutation	A	G	p.I242M
MEWO_SKIN	73096102	73096911	73096588	73096588	Missense_Mutation	T	G	p.I277S
HELA_CERVIX	73096102	73096911	73096609	73096609	Missense_Mutation	A	G	p.N284S
ES5_BONE	73096102	73096911	73096611	73096611	Missense_Mutation	A	G	p.I285V
RKN_SOFT_TISSUE	73096102	73096911	73096632	73096632	Missense_Mutation	G	C	p.G292R
HEC59_ENDOMETRIUM	73096102	73096911	73096641	73096641	Missense_Mutation	G	A	p.A295T
HEC6_ENDOMETRIUM	73096102	73096911	73096641	73096641	Missense_Mutation	G	A	p.A295T
SNUC1_LARGE_INTESTINE	73096102	73096911	73096648	73096648	Missense_Mutation	G	A	p.R297Q
HEC6_ENDOMETRIUM	73096102	73096911	73096684	73096684	Missense_Mutation	G	A	p.S309N
MDAMB415_BREAST	73096102	73096911	73096737	73096737	Missense_Mutation	G	A	p.D327N
HEC59_ENDOMETRIUM	73096102	73096911	73096818	73096818	Missense_Mutation	A	G	p.M354V
NCIH2087_LUNG	73096102	73096911	73096841	73096841	Missense_Mutation	G	T	p.Q361H
NCIH1339_LUNG	73096102	73096911	73096129	73096129	Nonsense_Mutation	C	A	p.S124*

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for SLC16A5

sQTL information located at the skipped exons.

Exon skip ID

Chromosome

Three exons

Skippped exon

ENST

Cancer type

SNP id

Location

DNA change (ref/var)

P-value

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for SLC16A5

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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for SLC16A5

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RelatedDrugs for SLC16A5

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for SLC16A5

Diseases associated with this gene.
(DisGeNet 4.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	Gene structures and expression levels
	Exon skipping events with PSIs in TCGA
	Exon skipping events with PSIs in GTEx
	Open reading frame (ORF) annotation in the exon skipping event
	Exon skipping events in the canonical protein sequence
	SNVs in the skipped exons with depth of coverage
	Splicing Quantitative Trait Loci (sQTLs) in the skipped exons
	Splicing Quantitative Trait Methylation (sQTM) in the skipped exon
	Related drugs with this gene
	Related diseases with this gene

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Gene summary for SLC16A5

Exon skipping events across known transcript of Ensembl for SLC16A5 from UCSC genome browser

Gene isoform structures and expression levels for SLC16A5

Exon skipping events with PSIs in TCGA for SLC16A5

Exon skipping events with PSIs in GTEx for SLC16A5

Open reading frame (ORF) annotation in the exon skipping event for SLC16A5

Infer the effects of exon skipping event on protein functional features for SLC16A5

SNVs in the skipped exons for SLC16A5

Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for SLC16A5

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for SLC16A5

Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for SLC16A5

RelatedDrugs for SLC16A5

RelatedDiseases for SLC16A5