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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for STARD13 |
 Gene summary |
| Gene information | Gene symbol | STARD13 | Gene ID | 90627 |
| Gene name | StAR related lipid transfer domain containing 13 | |
| Synonyms | ARHGAP37|DLC2|GT650|LINC00464 | |
| Cytomap | 13q13.1-q13.2 | |
| Type of gene | protein-coding | |
| Description | stAR-related lipid transfer protein 13Rho GTPase activating protein on chromosome 13q12StAR-related lipid transfer (START) domain containing 13deleted in liver cancer 2 proteinlong intergenic non-protein coding RNA 464 | |
| Modification date | 20180519 | |
| UniProtAcc | Q9Y3M8 | |
| Context | PubMed: STARD13 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for STARD13 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for STARD13 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for STARD13 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_102888 | 13 | 33680894:33681071:33684009:33684227:33684822:33685044 | 33684009:33684227 | ENSG00000133121.16 | ENST00000255486.4,ENST00000336934.5,ENST00000399365.3 |
| exon_skip_102890 | 13 | 33684822:33685044:33685914:33686029:33686857:33687068 | 33685914:33686029 | ENSG00000133121.16 | ENST00000255486.4,ENST00000336934.5,ENST00000399365.3 |
| exon_skip_102892 | 13 | 33692201:33692400:33700217:33700377:33701509:33701683 | 33700217:33700377 | ENSG00000133121.16 | ENST00000255486.4,ENST00000336934.5,ENST00000399365.3 |
| exon_skip_102893 | 13 | 33716446:33716510:33739473:33739555:33741687:33741759 | 33739473:33739555 | ENSG00000133121.16 | ENST00000567873.1,ENST00000255486.4,ENST00000336934.5,ENST00000487412.1,ENST00000399365.3 |
| exon_skip_102898 | 13 | 33739473:33739555:33741687:33741759:33859606:33859844 | 33741687:33741759 | ENSG00000133121.16 | ENST00000498019.2,ENST00000487412.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for STARD13 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_102888 | 13 | 33680894:33681071:33684009:33684227:33684822:33685044 | 33684009:33684227 | ENSG00000133121.16 | ENST00000336934.5,ENST00000255486.4,ENST00000399365.3 |
| exon_skip_102890 | 13 | 33684822:33685044:33685914:33686029:33686857:33687068 | 33685914:33686029 | ENSG00000133121.16 | ENST00000336934.5,ENST00000255486.4,ENST00000399365.3 |
| exon_skip_102892 | 13 | 33692201:33692400:33700217:33700377:33701509:33701683 | 33700217:33700377 | ENSG00000133121.16 | ENST00000336934.5,ENST00000255486.4,ENST00000399365.3 |
| exon_skip_102893 | 13 | 33716446:33716510:33739473:33739555:33741687:33741759 | 33739473:33739555 | ENSG00000133121.16 | ENST00000336934.5,ENST00000255486.4,ENST00000399365.3,ENST00000567873.1,ENST00000487412.1 |
| exon_skip_102898 | 13 | 33739473:33739555:33741687:33741759:33859606:33859844 | 33741687:33741759 | ENSG00000133121.16 | ENST00000487412.1,ENST00000498019.2 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for STARD13 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000336934 | 33684009 | 33684227 | Frame-shift |
| ENST00000336934 | 33685914 | 33686029 | Frame-shift |
| ENST00000336934 | 33700217 | 33700377 | Frame-shift |
| ENST00000336934 | 33739473 | 33739555 | Frame-shift |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000336934 | 33684009 | 33684227 | Frame-shift |
| ENST00000336934 | 33685914 | 33686029 | Frame-shift |
| ENST00000336934 | 33700217 | 33700377 | Frame-shift |
| ENST00000336934 | 33739473 | 33739555 | Frame-shift |
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Infer the effects of exon skipping event on protein functional features for STARD13 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for STARD13 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_102888 | 33684010 | 33684227 | 33684038 | 33684038 | Frame_Shift_Del | G | - | p.H1007fs |
| COAD | TCGA-AY-6197-01 | exon_skip_102888 | 33684010 | 33684227 | 33684168 | 33684168 | Frame_Shift_Del | G | - | p.S846fs |
| HNSC | TCGA-QK-A6VB-01 | exon_skip_102888 | 33684010 | 33684227 | 33684168 | 33684168 | Frame_Shift_Del | G | - | p.P963fs |
| PRAD | TCGA-EJ-7782-01 | exon_skip_102888 | 33684010 | 33684227 | 33684168 | 33684168 | Frame_Shift_Del | G | - | p.P963fs |
| PRAD | TCGA-EJ-7782-01 | exon_skip_102888 | 33684010 | 33684227 | 33684168 | 33684168 | Frame_Shift_Del | G | - | p.S964fs |
| GBM | TCGA-76-6664-01 | exon_skip_102890 | 33685915 | 33686029 | 33685935 | 33685935 | Nonsense_Mutation | C | A | p.E863* |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| 2313287_STOMACH | 33684010 | 33684227 | 33684168 | 33684168 | Frame_Shift_Del | G | - | p.P963fs |
| DG75_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 33684010 | 33684227 | 33684168 | 33684168 | Frame_Shift_Del | G | - | p.P963fs |
| HEC108_ENDOMETRIUM | 33684010 | 33684227 | 33684109 | 33684109 | Missense_Mutation | T | C | p.Q983R |
| SNU1066_UPPER_AERODIGESTIVE_TRACT | 33684010 | 33684227 | 33684170 | 33684170 | Missense_Mutation | G | C | p.P963A |
| T3M4_PANCREAS | 33685915 | 33686029 | 33685936 | 33685936 | Missense_Mutation | C | T | p.M862I |
| HCT15_LARGE_INTESTINE | 33685915 | 33686029 | 33685958 | 33685958 | Missense_Mutation | T | C | p.Q855R |
| SW684_SOFT_TISSUE | 33685915 | 33686029 | 33685977 | 33685977 | Missense_Mutation | C | T | p.E849K |
| HT115_LARGE_INTESTINE | 33700218 | 33700377 | 33700264 | 33700264 | Missense_Mutation | C | A | p.S679I |
| SNU1040_LARGE_INTESTINE | 33700218 | 33700377 | 33700358 | 33700358 | Missense_Mutation | T | C | p.K648E |
| HCC95_LUNG | 33739474 | 33739555 | 33739477 | 33739477 | Missense_Mutation | C | A | p.C107F |
| FARAGE_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 33684010 | 33684227 | 33684126 | 33684126 | Nonsense_Mutation | C | T | p.W977* |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for STARD13 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for STARD13 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for STARD13 |
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RelatedDrugs for STARD13 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for STARD13 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| STARD13 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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