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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for MFSD11 |
 Gene summary |
| Gene information | Gene symbol | MFSD11 | Gene ID | 79157 |
| Gene name | major facilitator superfamily domain containing 11 | |
| Synonyms | ET | |
| Cytomap | 17q25.1-q25.2 | |
| Type of gene | protein-coding | |
| Description | UNC93-like protein MFSD11major facilitator superfamily domain-containing protein 11protein ET | |
| Modification date | 20180519 | |
| UniProtAcc | O43934 | |
| Context | PubMed: MFSD11 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for MFSD11 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for MFSD11 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for MFSD11 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_156567 | 17 | 74735019:74735075:74737038:74737146:74738050:74738130 | 74737038:74737146 | ENSG00000092931.7 | ENST00000355954.3,ENST00000588460.1,ENST00000593181.1,ENST00000590514.1,ENST00000336509.4,ENST00000588768.1,ENST00000586622.1,ENST00000587661.1 |
| exon_skip_156568 | 17 | 74738100:74738130:74738258:74738355:74739479:74739538 | 74738258:74738355 | ENSG00000092931.7 | ENST00000588460.1,ENST00000590514.1,ENST00000336509.4,ENST00000588031.1,ENST00000586622.1 |
| exon_skip_156569 | 17 | 74738100:74738130:74738258:74738355:74740403:74740548 | 74738258:74738355 | ENSG00000092931.7 | ENST00000588768.1,ENST00000588670.1 |
| exon_skip_156572 | 17 | 74738272:74738355:74739479:74739538:74740403:74740548 | 74739479:74739538 | ENSG00000092931.7 | ENST00000588460.1,ENST00000590514.1,ENST00000336509.4,ENST00000588031.1,ENST00000586622.1,ENST00000585584.1 |
| exon_skip_156573 | 17 | 74738272:74738355:74740403:74740548:74750128:74750169 | 74740403:74740548 | ENSG00000092931.7 | ENST00000588768.1,ENST00000588670.1 |
| exon_skip_156575 | 17 | 74740403:74740548:74741474:74741521:74750128:74750169 | 74741474:74741521 | ENSG00000092931.7 | ENST00000585584.1 |
| exon_skip_156576 | 17 | 74740403:74740548:74750128:74750169:74763467:74763533 | 74750128:74750169 | ENSG00000092931.7 | ENST00000355954.3,ENST00000588460.1,ENST00000593181.1,ENST00000590514.1,ENST00000336509.4,ENST00000588768.1,ENST00000586622.1,ENST00000588670.1 |
| exon_skip_156579 | 17 | 74750128:74750169:74763467:74763533:74765827:74765922 | 74763467:74763533 | ENSG00000092931.7 | ENST00000355954.3,ENST00000588460.1,ENST00000593181.1,ENST00000590514.1,ENST00000336509.4,ENST00000588768.1,ENST00000586622.1,ENST00000585584.1,ENST00000588670.1 |
| exon_skip_156580 | 17 | 74763522:74763533:74765827:74765953:74771078:74771163 | 74765827:74765953 | ENSG00000092931.7 | ENST00000585692.1,ENST00000355954.3,ENST00000588460.1,ENST00000593181.1,ENST00000590514.1,ENST00000336509.4,ENST00000588768.1,ENST00000585865.1,ENST00000585958.1,ENST00000586622.1 |
| exon_skip_156581 | 17 | 74765827:74765953:74771078:74771253:74772487:74772623 | 74771078:74771253 | ENSG00000092931.7 | ENST00000585692.1,ENST00000355954.3,ENST00000588460.1,ENST00000593181.1,ENST00000590514.1,ENST00000336509.4,ENST00000585865.1,ENST00000586622.1 |
| exon_skip_156583 | 17 | 74771078:74771253:74772487:74772623:74774269:74774347 | 74772487:74772623 | ENSG00000092931.7 | ENST00000585692.1,ENST00000355954.3,ENST00000588460.1,ENST00000593181.1,ENST00000590514.1,ENST00000336509.4,ENST00000586622.1,ENST00000590070.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for MFSD11 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_156568 | 17 | 74738100:74738130:74738258:74738355:74739479:74739538 | 74738258:74738355 | ENSG00000092931.7 | ENST00000586622.1,ENST00000588460.1,ENST00000336509.4,ENST00000590514.1,ENST00000588031.1 |
| exon_skip_156569 | 17 | 74738100:74738130:74738258:74738355:74740403:74740548 | 74738258:74738355 | ENSG00000092931.7 | ENST00000588670.1,ENST00000588768.1 |
| exon_skip_156572 | 17 | 74738272:74738355:74739479:74739538:74740403:74740548 | 74739479:74739538 | ENSG00000092931.7 | ENST00000586622.1,ENST00000588460.1,ENST00000336509.4,ENST00000590514.1,ENST00000588031.1,ENST00000585584.1 |
| exon_skip_156573 | 17 | 74738272:74738355:74740403:74740548:74750128:74750169 | 74740403:74740548 | ENSG00000092931.7 | ENST00000588670.1,ENST00000588768.1 |
| exon_skip_156575 | 17 | 74740403:74740548:74741474:74741521:74750128:74750169 | 74741474:74741521 | ENSG00000092931.7 | ENST00000585584.1 |
| exon_skip_156576 | 17 | 74740403:74740548:74750128:74750169:74763467:74763533 | 74750128:74750169 | ENSG00000092931.7 | ENST00000586622.1,ENST00000588460.1,ENST00000593181.1,ENST00000336509.4,ENST00000355954.3,ENST00000590514.1,ENST00000588670.1,ENST00000588768.1 |
| exon_skip_156579 | 17 | 74750128:74750169:74763467:74763533:74765827:74765922 | 74763467:74763533 | ENSG00000092931.7 | ENST00000586622.1,ENST00000588460.1,ENST00000593181.1,ENST00000336509.4,ENST00000355954.3,ENST00000590514.1,ENST00000588670.1,ENST00000588768.1,ENST00000585584.1 |
| exon_skip_156580 | 17 | 74763522:74763533:74765827:74765953:74771078:74771163 | 74765827:74765953 | ENSG00000092931.7 | ENST00000586622.1,ENST00000588460.1,ENST00000593181.1,ENST00000336509.4,ENST00000355954.3,ENST00000590514.1,ENST00000588768.1,ENST00000585958.1,ENST00000585692.1,ENST00000585865.1 |
| exon_skip_156581 | 17 | 74765827:74765953:74771078:74771253:74772487:74772623 | 74771078:74771253 | ENSG00000092931.7 | ENST00000586622.1,ENST00000588460.1,ENST00000593181.1,ENST00000336509.4,ENST00000355954.3,ENST00000590514.1,ENST00000585692.1,ENST00000585865.1 |
| exon_skip_156583 | 17 | 74771078:74771253:74772487:74772623:74774269:74774347 | 74772487:74772623 | ENSG00000092931.7 | ENST00000586622.1,ENST00000588460.1,ENST00000593181.1,ENST00000336509.4,ENST00000355954.3,ENST00000590514.1,ENST00000585692.1,ENST00000590070.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for MFSD11 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000336509 | 74738258 | 74738355 | Frame-shift |
| ENST00000586622 | 74738258 | 74738355 | Frame-shift |
| ENST00000588460 | 74738258 | 74738355 | Frame-shift |
| ENST00000590514 | 74738258 | 74738355 | Frame-shift |
| ENST00000336509 | 74739479 | 74739538 | Frame-shift |
| ENST00000586622 | 74739479 | 74739538 | Frame-shift |
| ENST00000588460 | 74739479 | 74739538 | Frame-shift |
| ENST00000590514 | 74739479 | 74739538 | Frame-shift |
| ENST00000336509 | 74750128 | 74750169 | Frame-shift |
| ENST00000586622 | 74750128 | 74750169 | Frame-shift |
| ENST00000588460 | 74750128 | 74750169 | Frame-shift |
| ENST00000590514 | 74750128 | 74750169 | Frame-shift |
| ENST00000336509 | 74771078 | 74771253 | Frame-shift |
| ENST00000586622 | 74771078 | 74771253 | Frame-shift |
| ENST00000588460 | 74771078 | 74771253 | Frame-shift |
| ENST00000590514 | 74771078 | 74771253 | Frame-shift |
| ENST00000336509 | 74772487 | 74772623 | Frame-shift |
| ENST00000586622 | 74772487 | 74772623 | Frame-shift |
| ENST00000588460 | 74772487 | 74772623 | Frame-shift |
| ENST00000590514 | 74772487 | 74772623 | Frame-shift |
| ENST00000336509 | 74737038 | 74737146 | In-frame |
| ENST00000586622 | 74737038 | 74737146 | In-frame |
| ENST00000588460 | 74737038 | 74737146 | In-frame |
| ENST00000590514 | 74737038 | 74737146 | In-frame |
| ENST00000336509 | 74763467 | 74763533 | In-frame |
| ENST00000586622 | 74763467 | 74763533 | In-frame |
| ENST00000588460 | 74763467 | 74763533 | In-frame |
| ENST00000590514 | 74763467 | 74763533 | In-frame |
| ENST00000336509 | 74765827 | 74765953 | In-frame |
| ENST00000586622 | 74765827 | 74765953 | In-frame |
| ENST00000588460 | 74765827 | 74765953 | In-frame |
| ENST00000590514 | 74765827 | 74765953 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000336509 | 74738258 | 74738355 | Frame-shift |
| ENST00000586622 | 74738258 | 74738355 | Frame-shift |
| ENST00000588460 | 74738258 | 74738355 | Frame-shift |
| ENST00000590514 | 74738258 | 74738355 | Frame-shift |
| ENST00000336509 | 74739479 | 74739538 | Frame-shift |
| ENST00000586622 | 74739479 | 74739538 | Frame-shift |
| ENST00000588460 | 74739479 | 74739538 | Frame-shift |
| ENST00000590514 | 74739479 | 74739538 | Frame-shift |
| ENST00000336509 | 74750128 | 74750169 | Frame-shift |
| ENST00000586622 | 74750128 | 74750169 | Frame-shift |
| ENST00000588460 | 74750128 | 74750169 | Frame-shift |
| ENST00000590514 | 74750128 | 74750169 | Frame-shift |
| ENST00000336509 | 74771078 | 74771253 | Frame-shift |
| ENST00000586622 | 74771078 | 74771253 | Frame-shift |
| ENST00000588460 | 74771078 | 74771253 | Frame-shift |
| ENST00000590514 | 74771078 | 74771253 | Frame-shift |
| ENST00000336509 | 74772487 | 74772623 | Frame-shift |
| ENST00000586622 | 74772487 | 74772623 | Frame-shift |
| ENST00000588460 | 74772487 | 74772623 | Frame-shift |
| ENST00000590514 | 74772487 | 74772623 | Frame-shift |
| ENST00000336509 | 74763467 | 74763533 | In-frame |
| ENST00000586622 | 74763467 | 74763533 | In-frame |
| ENST00000588460 | 74763467 | 74763533 | In-frame |
| ENST00000590514 | 74763467 | 74763533 | In-frame |
| ENST00000336509 | 74765827 | 74765953 | In-frame |
| ENST00000586622 | 74765827 | 74765953 | In-frame |
| ENST00000588460 | 74765827 | 74765953 | In-frame |
| ENST00000590514 | 74765827 | 74765953 | In-frame |
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Infer the effects of exon skipping event on protein functional features for MFSD11 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000336509 | 2555 | 449 | 74737038 | 74737146 | 407 | 514 | 51 | 86 |
| ENST00000586622 | 2969 | 449 | 74737038 | 74737146 | 1290 | 1397 | 51 | 86 |
| ENST00000588460 | 3629 | 449 | 74737038 | 74737146 | 2195 | 2302 | 51 | 86 |
| ENST00000590514 | 1908 | 449 | 74737038 | 74737146 | 319 | 426 | 51 | 86 |
| ENST00000336509 | 2555 | 449 | 74763467 | 74763533 | 937 | 1002 | 227 | 249 |
| ENST00000586622 | 2969 | 449 | 74763467 | 74763533 | 1820 | 1885 | 227 | 249 |
| ENST00000588460 | 3629 | 449 | 74763467 | 74763533 | 2725 | 2790 | 227 | 249 |
| ENST00000590514 | 1908 | 449 | 74763467 | 74763533 | 849 | 914 | 227 | 249 |
| ENST00000336509 | 2555 | 449 | 74765827 | 74765953 | 1003 | 1128 | 249 | 291 |
| ENST00000586622 | 2969 | 449 | 74765827 | 74765953 | 1886 | 2011 | 249 | 291 |
| ENST00000588460 | 3629 | 449 | 74765827 | 74765953 | 2791 | 2916 | 249 | 291 |
| ENST00000590514 | 1908 | 449 | 74765827 | 74765953 | 915 | 1040 | 249 | 291 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000336509 | 2555 | 449 | 74763467 | 74763533 | 937 | 1002 | 227 | 249 |
| ENST00000586622 | 2969 | 449 | 74763467 | 74763533 | 1820 | 1885 | 227 | 249 |
| ENST00000588460 | 3629 | 449 | 74763467 | 74763533 | 2725 | 2790 | 227 | 249 |
| ENST00000590514 | 1908 | 449 | 74763467 | 74763533 | 849 | 914 | 227 | 249 |
| ENST00000336509 | 2555 | 449 | 74765827 | 74765953 | 1003 | 1128 | 249 | 291 |
| ENST00000586622 | 2969 | 449 | 74765827 | 74765953 | 1886 | 2011 | 249 | 291 |
| ENST00000588460 | 3629 | 449 | 74765827 | 74765953 | 2791 | 2916 | 249 | 291 |
| ENST00000590514 | 1908 | 449 | 74765827 | 74765953 | 915 | 1040 | 249 | 291 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| O43934 | 51 | 86 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 51 | 86 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 51 | 86 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 51 | 86 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 51 | 86 | 53 | 73 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 51 | 86 | 53 | 73 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 51 | 86 | 53 | 73 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 51 | 86 | 53 | 73 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 51 | 86 | 74 | 94 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 51 | 86 | 74 | 94 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 51 | 86 | 74 | 94 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 51 | 86 | 74 | 94 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 227 | 249 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 227 | 249 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 227 | 249 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 227 | 249 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 227 | 249 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 227 | 249 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 227 | 249 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 227 | 249 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 249 | 291 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 249 | 291 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 249 | 291 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 249 | 291 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 277 | 297 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 277 | 297 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 277 | 297 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 277 | 297 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| O43934 | 227 | 249 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 227 | 249 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 227 | 249 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 227 | 249 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 227 | 249 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 227 | 249 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 227 | 249 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 227 | 249 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 249 | 291 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 249 | 291 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 249 | 291 | 1 | 449 | Chain | ID=PRO_0000305019;Note=UNC93-like protein MFSD11 |
| O43934 | 249 | 291 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 239 | 259 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 277 | 297 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 277 | 297 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 277 | 297 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| O43934 | 249 | 291 | 277 | 297 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
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SNVs in the skipped exons for MFSD11 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
MFSD11_BRCA_exon_skip_156579_psi_boxplot.png |
MFSD11_COAD_exon_skip_156579_psi_boxplot.png |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LUSC | TCGA-18-4086-01 | exon_skip_156581 | 74771079 | 74771253 | 74771143 | 74771143 | Frame_Shift_Del | G | - | p.L313fs |
| COAD | TCGA-CK-5916-01 | exon_skip_156573 | 74740404 | 74740548 | 74740452 | 74740453 | Frame_Shift_Ins | - | G | p.V130fs |
| BLCA | TCGA-CU-A3YL-01 | exon_skip_156567 | 74737039 | 74737146 | 74737112 | 74737112 | Nonsense_Mutation | C | T | p.Q76* |
| UCEC | TCGA-D1-A17Q-01 | exon_skip_156580 | 74765828 | 74765953 | 74765944 | 74765944 | Nonsense_Mutation | G | T | p.E289* |
| KIRP | TCGA-BQ-5875-01 | exon_skip_156583 | 74772488 | 74772623 | 74772621 | 74772621 | Nonsense_Mutation | C | T | p.Q395* |
| KIRP | TCGA-BQ-5875-01 | exon_skip_156583 | 74772488 | 74772623 | 74772621 | 74772621 | Nonsense_Mutation | C | T | p.Q395X |
| LUAD | TCGA-55-8511-01 | exon_skip_156583 | 74772488 | 74772623 | 74772621 | 74772621 | Nonsense_Mutation | C | T | p.Q395* |
| KIRP | TCGA-AT-A5NU-01 | exon_skip_156568 exon_skip_156569 | 74738259 | 74738355 | 74738356 | 74738356 | Splice_Site | G | A | . |
| KIRP | TCGA-AT-A5NU-01 | exon_skip_156568 exon_skip_156569 | 74738259 | 74738355 | 74738356 | 74738356 | Splice_Site | G | A | p.S146_splice |
| BRCA | TCGA-A2-A0EY-01 | exon_skip_156579 | 74763468 | 74763533 | 74763467 | 74763467 | Splice_Site | G | A | e9-1 |
| COAD | TCGA-AM-5821-01 | exon_skip_156579 | 74763468 | 74763533 | 74763534 | 74763534 | Splice_Site | G | A | . |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
 | Sample: TCGA-A2-A0EY-01 |
| Cancer type: BRCA | |
| ESID: exon_skip_156579 | |
| Skipped exon start: 74763468 | |
| Skipped exon end: 74763533 | |
| Mutation start: 74763467 | |
| Mutation end: 74763467 | |
| Mutation type: Splice_Site | |
| Reference seq: G | |
| Mutation seq: A | |
| AAchange: e9-1 | |
exon_skip_156579_BRCA_TCGA-A2-A0EY-01.png | |
exon_skip_387350_BRCA_TCGA-A2-A0EY-01.png | |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| SUM149PT_BREAST | 74740404 | 74740548 | 74740423 | 74740424 | Frame_Shift_Ins | - | T | p.F173fs |
| BC3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 74738259 | 74738355 | 74738293 | 74738293 | Missense_Mutation | C | G | p.I125M |
| HCC2998_LARGE_INTESTINE | 74739480 | 74739538 | 74739496 | 74739496 | Missense_Mutation | C | A | p.L152I |
| HS706T_BONE | 74740404 | 74740548 | 74740446 | 74740446 | Missense_Mutation | G | A | p.S180N |
| HEPG2_LIVER | 74740404 | 74740548 | 74740454 | 74740454 | Missense_Mutation | G | A | p.G183R |
| NCIH1869_LUNG | 74740404 | 74740548 | 74740509 | 74740509 | Missense_Mutation | A | C | p.E201A |
| COLO679_SKIN | 74750129 | 74750169 | 74750131 | 74750131 | Missense_Mutation | C | T | p.S215F |
| SNB75_CENTRAL_NERVOUS_SYSTEM | 74763468 | 74763533 | 74763503 | 74763503 | Missense_Mutation | C | T | p.L240F |
| NCIH929_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 74763468 | 74763533 | 74763509 | 74763509 | Missense_Mutation | C | T | p.L242F |
| NCIH2110_LUNG | 74763468 | 74763533 | 74763521 | 74763521 | Missense_Mutation | A | T | p.T246S |
| BCP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 74763468 | 74763533 | 74763524 | 74763524 | Missense_Mutation | G | A | p.A247T |
| NCIH378_LUNG | 74771079 | 74771253 | 74771093 | 74771093 | Missense_Mutation | G | A | p.G297S |
| NCIH2347_LUNG | 74771079 | 74771253 | 74771111 | 74771111 | Missense_Mutation | A | G | p.N303D |
| JHH1_LIVER | 74771079 | 74771253 | 74771139 | 74771139 | Missense_Mutation | T | C | p.L312P |
| SNGM_ENDOMETRIUM | 74771079 | 74771253 | 74771191 | 74771191 | Missense_Mutation | G | A | p.M329I |
| JEKO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 74772488 | 74772623 | 74772507 | 74772507 | Missense_Mutation | T | A | p.C357S |
| JVM3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 74738259 | 74738355 | 74738348 | 74738348 | Nonsense_Mutation | C | T | p.Q144* |
| MOGGCCM_CENTRAL_NERVOUS_SYSTEM | 74750129 | 74750169 | 74750129 | 74750129 | Splice_Site | G | A | p.E214E |
| HEC251_ENDOMETRIUM | 74771079 | 74771253 | 74771080 | 74771080 | Splice_Site | T | C | p.G292G |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for MFSD11 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MFSD11 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MFSD11 |
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RelatedDrugs for MFSD11 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MFSD11 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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