|
||||||
|
 | |
| |
| |
| |
| Open reading frame (ORF) annotation in the exon skipping event |
| |
| |
| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
| |
|
Gene summary for ZNF185 |
 Gene summary |
| Gene information | Gene symbol | ZNF185 | Gene ID | 7739 |
| Gene name | zinc finger protein 185 with LIM domain | |
| Synonyms | SCELL | |
| Cytomap | Xq28 | |
| Type of gene | protein-coding | |
| Description | zinc finger protein 185P1-Asciellin likezinc finger protein 185 (LIM domain) | |
| Modification date | 20180519 | |
| UniProtAcc | O15231 | |
| Context | PubMed: ZNF185 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
Exon skipping events across known transcript of Ensembl for ZNF185 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
Top |
Gene isoform structures and expression levels for ZNF185 |
| Expression levels of gene isoforms across TCGA. |
 |
| Expression levels of gene isoforms across GTEx. |
 |
Top |
Exon skipping events with PSIs in TCGA for ZNF185 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_512782 | X | 152083253:152083377:152083681:152083747:152085674:152085713 | 152083681:152083747 | ENSG00000147394.14 | ENST00000370270.2,ENST00000535861.1,ENST00000324823.6,ENST00000449285.2,ENST00000370268.4,ENST00000539731.1,ENST00000436731.2,ENST00000318504.7 |
| exon_skip_512785 | X | 152087544:152087625:152088871:152088955:152089250:152089292 | 152088871:152088955 | ENSG00000147394.14 | ENST00000324823.6,ENST00000449285.2 |
| exon_skip_512786 | X | 152087526:152087625:152088871:152088955:152089253:152089292 | 152088871:152088955 | ENSG00000147394.14 | ENST00000370270.2,ENST00000535861.1,ENST00000370268.4,ENST00000539731.1,ENST00000436731.2,ENST00000318504.7 |
| exon_skip_512789 | X | 152089253:152089292:152090716:152090800:152097118:152097205 | 152090716:152090800 | ENSG00000147394.14 | ENST00000324823.6 |
| exon_skip_512790 | X | 152089253:152089292:152090716:152090800:152100215:152100320 | 152090716:152090800 | ENSG00000147394.14 | ENST00000318529.8,ENST00000426821.2,ENST00000318504.7 |
| exon_skip_512792 | X | 152090716:152090800:152091263:152091353:152097118:152097205 | 152091263:152091353 | ENSG00000147394.14 | ENST00000370270.2,ENST00000535861.1,ENST00000449285.2,ENST00000370268.4 |
| exon_skip_512793 | X | 152090716:152090800:152091263:152091353:152100215:152100320 | 152091263:152091353 | ENSG00000147394.14 | ENST00000447792.2,ENST00000539731.1,ENST00000436731.2 |
| exon_skip_512795 | X | 152091263:152091353:152097118:152097205:152100215:152100320 | 152097118:152097205 | ENSG00000147394.14 | ENST00000370270.2,ENST00000535861.1,ENST00000449285.2,ENST00000370268.4 |
| exon_skip_512798 | X | 152100215:152100320:152101416:152101515:152104961:152105057 | 152101416:152101515 | ENSG00000147394.14 | ENST00000370270.2,ENST00000535861.1,ENST00000539731.1,ENST00000436731.2 |
| exon_skip_512799 | X | 152100215:152100320:152101416:152101515:152106617:152106707 | 152101416:152101515 | ENSG00000147394.14 | ENST00000318529.8,ENST00000449285.2,ENST00000370268.4,ENST00000426821.2,ENST00000318504.7 |
| exon_skip_512809 | X | 152101416:152101515:152104961:152105057:152106617:152106707 | 152104961:152105057 | ENSG00000147394.14 | ENST00000370270.2,ENST00000535861.1,ENST00000539731.1,ENST00000436731.2 |
| exon_skip_512812 | X | 152101416:152101515:152106617:152106707:152113810:152114008 | 152106617:152106707 | ENSG00000147394.14 | ENST00000318529.8,ENST00000449285.2,ENST00000370268.4,ENST00000426821.2,ENST00000318504.7 |
| exon_skip_512814 | X | 152104961:152105057:152106617:152106707:152113810:152114008 | 152106617:152106707 | ENSG00000147394.14 | ENST00000370270.2,ENST00000535861.1,ENST00000539731.1,ENST00000436731.2 |
| exon_skip_512816 | X | 152106623:152106707:152113810:152114008:152128242:152128385 | 152113810:152114008 | ENSG00000147394.14 | ENST00000370270.2,ENST00000318529.8,ENST00000535861.1,ENST00000324823.6,ENST00000449285.2,ENST00000370268.4,ENST00000539731.1,ENST00000436731.2,ENST00000426821.2,ENST00000318504.7 |
| exon_skip_512819 | X | 152113810:152114008:152128242:152128440:152132382:152132493 | 152128242:152128440 | ENSG00000147394.14 | ENST00000370270.2,ENST00000318529.8,ENST00000535861.1,ENST00000324823.6,ENST00000449285.2,ENST00000370268.4,ENST00000539731.1,ENST00000426821.2,ENST00000454925.1,ENST00000318504.7 |
| exon_skip_512821 | X | 152113810:152114008:152128242:152128481:152132382:152132493 | 152128242:152128481 | ENSG00000147394.14 | ENST00000436731.2 |
| exon_skip_512824 | X | 152128242:152128440:152132382:152132493:152133990:152134071 | 152132382:152132493 | ENSG00000147394.14 | ENST00000370270.2,ENST00000318529.8,ENST00000535861.1,ENST00000324823.6,ENST00000449285.2,ENST00000370268.4,ENST00000539731.1,ENST00000426821.2,ENST00000454925.1,ENST00000318504.7 |
| exon_skip_512828 | X | 152132382:152132493:152133990:152134071:152135710:152135782 | 152133990:152134071 | ENSG00000147394.14 | ENST00000370270.2,ENST00000318529.8,ENST00000535861.1,ENST00000324823.6,ENST00000449285.2,ENST00000370268.4,ENST00000539731.1,ENST00000436731.2,ENST00000426821.2,ENST00000454925.1,ENST00000318504.7 |
| exon_skip_512829 | X | 152135710:152135782:152137925:152138028:152138986:152139085 | 152137925:152138028 | ENSG00000147394.14 | ENST00000370270.2,ENST00000318529.8,ENST00000535861.1,ENST00000324823.6,ENST00000449285.2,ENST00000370268.4,ENST00000539731.1,ENST00000436731.2,ENST00000426821.2,ENST00000454925.1,ENST00000318504.7 |
| exon_skip_512830 | X | 152137925:152138028:152138986:152139085:152139817:152142015 | 152138986:152139085 | ENSG00000147394.14 | ENST00000318529.8,ENST00000535861.1,ENST00000324823.6,ENST00000449285.2,ENST00000370268.4,ENST00000539731.1,ENST00000426821.2,ENST00000454925.1,ENST00000318504.7 |
| PSI values of skipped exons in TCGA. |
 |
Top |
Exon skipping events with PSIs in GTEx for ZNF185 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_512782 | X | 152083253:152083377:152083681:152083747:152085674:152085713 | 152083681:152083747 | ENSG00000147394.14 | ENST00000535861.1,ENST00000539731.1,ENST00000449285.2,ENST00000318504.7,ENST00000324823.6,ENST00000370268.4,ENST00000436731.2,ENST00000370270.2 |
| exon_skip_512785 | X | 152087544:152087625:152088871:152088955:152089250:152089292 | 152088871:152088955 | ENSG00000147394.14 | ENST00000449285.2,ENST00000324823.6 |
| exon_skip_512786 | X | 152087526:152087625:152088871:152088955:152089253:152089292 | 152088871:152088955 | ENSG00000147394.14 | ENST00000535861.1,ENST00000539731.1,ENST00000318504.7,ENST00000370268.4,ENST00000436731.2,ENST00000370270.2 |
| exon_skip_512789 | X | 152089253:152089292:152090716:152090800:152097118:152097205 | 152090716:152090800 | ENSG00000147394.14 | ENST00000324823.6 |
| exon_skip_512790 | X | 152089253:152089292:152090716:152090800:152100215:152100320 | 152090716:152090800 | ENSG00000147394.14 | ENST00000318504.7,ENST00000318529.8,ENST00000426821.2 |
| exon_skip_512792 | X | 152090716:152090800:152091263:152091353:152097118:152097205 | 152091263:152091353 | ENSG00000147394.14 | ENST00000535861.1,ENST00000449285.2,ENST00000370268.4,ENST00000370270.2 |
| exon_skip_512793 | X | 152090716:152090800:152091263:152091353:152100215:152100320 | 152091263:152091353 | ENSG00000147394.14 | ENST00000539731.1,ENST00000436731.2,ENST00000447792.2 |
| exon_skip_512795 | X | 152091263:152091353:152097118:152097205:152100215:152100320 | 152097118:152097205 | ENSG00000147394.14 | ENST00000535861.1,ENST00000449285.2,ENST00000370268.4,ENST00000370270.2 |
| exon_skip_512798 | X | 152100215:152100320:152101416:152101515:152104961:152105057 | 152101416:152101515 | ENSG00000147394.14 | ENST00000535861.1,ENST00000539731.1,ENST00000436731.2,ENST00000370270.2 |
| exon_skip_512799 | X | 152100215:152100320:152101416:152101515:152106617:152106707 | 152101416:152101515 | ENSG00000147394.14 | ENST00000449285.2,ENST00000318504.7,ENST00000370268.4,ENST00000318529.8,ENST00000426821.2 |
| exon_skip_512809 | X | 152101416:152101515:152104961:152105057:152106617:152106707 | 152104961:152105057 | ENSG00000147394.14 | ENST00000535861.1,ENST00000539731.1,ENST00000436731.2,ENST00000370270.2 |
| exon_skip_512812 | X | 152101416:152101515:152106617:152106707:152113810:152114008 | 152106617:152106707 | ENSG00000147394.14 | ENST00000449285.2,ENST00000318504.7,ENST00000370268.4,ENST00000318529.8,ENST00000426821.2 |
| exon_skip_512816 | X | 152106623:152106707:152113810:152114008:152128242:152128385 | 152113810:152114008 | ENSG00000147394.14 | ENST00000535861.1,ENST00000539731.1,ENST00000449285.2,ENST00000318504.7,ENST00000324823.6,ENST00000370268.4,ENST00000436731.2,ENST00000370270.2,ENST00000318529.8,ENST00000426821.2 |
| exon_skip_512819 | X | 152113810:152114008:152128242:152128440:152132382:152132493 | 152128242:152128440 | ENSG00000147394.14 | ENST00000535861.1,ENST00000539731.1,ENST00000449285.2,ENST00000318504.7,ENST00000324823.6,ENST00000370268.4,ENST00000370270.2,ENST00000318529.8,ENST00000426821.2,ENST00000454925.1 |
| exon_skip_512824 | X | 152128242:152128440:152132382:152132493:152133990:152134071 | 152132382:152132493 | ENSG00000147394.14 | ENST00000535861.1,ENST00000539731.1,ENST00000449285.2,ENST00000318504.7,ENST00000324823.6,ENST00000370268.4,ENST00000370270.2,ENST00000318529.8,ENST00000426821.2,ENST00000454925.1 |
| exon_skip_512828 | X | 152132382:152132493:152133990:152134071:152135710:152135782 | 152133990:152134071 | ENSG00000147394.14 | ENST00000535861.1,ENST00000539731.1,ENST00000449285.2,ENST00000318504.7,ENST00000324823.6,ENST00000370268.4,ENST00000436731.2,ENST00000370270.2,ENST00000318529.8,ENST00000426821.2,ENST00000454925.1 |
| exon_skip_512829 | X | 152135710:152135782:152137925:152138028:152138986:152139085 | 152137925:152138028 | ENSG00000147394.14 | ENST00000535861.1,ENST00000539731.1,ENST00000449285.2,ENST00000318504.7,ENST00000324823.6,ENST00000370268.4,ENST00000436731.2,ENST00000370270.2,ENST00000318529.8,ENST00000426821.2,ENST00000454925.1 |
| exon_skip_512830 | X | 152137925:152138028:152138986:152139085:152139817:152142015 | 152138986:152139085 | ENSG00000147394.14 | ENST00000535861.1,ENST00000539731.1,ENST00000449285.2,ENST00000318504.7,ENST00000324823.6,ENST00000370268.4,ENST00000318529.8,ENST00000426821.2,ENST00000454925.1 |
| PSI values of skipped exons in GTEx. |
 |
| * Skipped exon sequences. |
Top |
Open reading frame (ORF) annotation in the exon skipping event for ZNF185 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000370268 | 152137925 | 152138028 | Frame-shift |
| ENST00000370268 | 152083681 | 152083747 | In-frame |
| ENST00000370268 | 152088871 | 152088955 | In-frame |
| ENST00000370268 | 152091263 | 152091353 | In-frame |
| ENST00000370268 | 152097118 | 152097205 | In-frame |
| ENST00000370268 | 152101416 | 152101515 | In-frame |
| ENST00000370268 | 152106617 | 152106707 | In-frame |
| ENST00000370268 | 152113810 | 152114008 | In-frame |
| ENST00000370268 | 152128242 | 152128440 | In-frame |
| ENST00000370268 | 152132382 | 152132493 | In-frame |
| ENST00000370268 | 152133990 | 152134071 | In-frame |
| ENST00000370268 | 152138986 | 152139085 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000370268 | 152137925 | 152138028 | Frame-shift |
| ENST00000370268 | 152083681 | 152083747 | In-frame |
| ENST00000370268 | 152088871 | 152088955 | In-frame |
| ENST00000370268 | 152091263 | 152091353 | In-frame |
| ENST00000370268 | 152097118 | 152097205 | In-frame |
| ENST00000370268 | 152101416 | 152101515 | In-frame |
| ENST00000370268 | 152106617 | 152106707 | In-frame |
| ENST00000370268 | 152113810 | 152114008 | In-frame |
| ENST00000370268 | 152128242 | 152128440 | In-frame |
| ENST00000370268 | 152132382 | 152132493 | In-frame |
| ENST00000370268 | 152133990 | 152134071 | In-frame |
| ENST00000370268 | 152138986 | 152139085 | In-frame |
Top |
Infer the effects of exon skipping event on protein functional features for ZNF185 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
 |
| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000370268 | 4322 | 689 | 152083681 | 152083747 | 196 | 261 | 53 | 74 |
| ENST00000370268 | 4322 | 689 | 152088871 | 152088955 | 568 | 651 | 177 | 204 |
| ENST00000370268 | 4322 | 689 | 152091263 | 152091353 | 775 | 864 | 246 | 275 |
| ENST00000370268 | 4322 | 689 | 152097118 | 152097205 | 865 | 951 | 276 | 304 |
| ENST00000370268 | 4322 | 689 | 152101416 | 152101515 | 1057 | 1155 | 340 | 372 |
| ENST00000370268 | 4322 | 689 | 152106617 | 152106707 | 1156 | 1245 | 373 | 402 |
| ENST00000370268 | 4322 | 689 | 152113810 | 152114008 | 1246 | 1443 | 403 | 468 |
| ENST00000370268 | 4322 | 689 | 152113810 | 152114008 | 1246 | 1443 | 403 | 468 |
| ENST00000370268 | 4322 | 689 | 152128242 | 152128440 | 1444 | 1641 | 469 | 534 |
| ENST00000370268 | 4322 | 689 | 152128242 | 152128440 | 1444 | 1641 | 469 | 534 |
| ENST00000370268 | 4322 | 689 | 152132382 | 152132493 | 1642 | 1752 | 535 | 571 |
| ENST00000370268 | 4322 | 689 | 152133990 | 152134071 | 1753 | 1833 | 572 | 598 |
| ENST00000370268 | 4322 | 689 | 152138986 | 152139085 | 2009 | 2107 | 657 | 690 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000370268 | 4322 | 689 | 152083681 | 152083747 | 196 | 261 | 53 | 74 |
| ENST00000370268 | 4322 | 689 | 152088871 | 152088955 | 568 | 651 | 177 | 204 |
| ENST00000370268 | 4322 | 689 | 152091263 | 152091353 | 775 | 864 | 246 | 275 |
| ENST00000370268 | 4322 | 689 | 152097118 | 152097205 | 865 | 951 | 276 | 304 |
| ENST00000370268 | 4322 | 689 | 152101416 | 152101515 | 1057 | 1155 | 340 | 372 |
| ENST00000370268 | 4322 | 689 | 152106617 | 152106707 | 1156 | 1245 | 373 | 402 |
| ENST00000370268 | 4322 | 689 | 152113810 | 152114008 | 1246 | 1443 | 403 | 468 |
| ENST00000370268 | 4322 | 689 | 152113810 | 152114008 | 1246 | 1443 | 403 | 468 |
| ENST00000370268 | 4322 | 689 | 152128242 | 152128440 | 1444 | 1641 | 469 | 534 |
| ENST00000370268 | 4322 | 689 | 152128242 | 152128440 | 1444 | 1641 | 469 | 534 |
| ENST00000370268 | 4322 | 689 | 152132382 | 152132493 | 1642 | 1752 | 535 | 571 |
| ENST00000370268 | 4322 | 689 | 152133990 | 152134071 | 1753 | 1833 | 572 | 598 |
| ENST00000370268 | 4322 | 689 | 152138986 | 152139085 | 2009 | 2107 | 657 | 690 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
Top |
SNVs in the skipped exons for ZNF185 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
 |
| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_512795 | 152097119 | 152097205 | 152097122 | 152097122 | Frame_Shift_Del | A | - | p.S277fs |
| HNSC | TCGA-BA-A6DA-01 | exon_skip_512812 exon_skip_512814 | 152106618 | 152106707 | 152106684 | 152106684 | Frame_Shift_Del | G | - | p.E427fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_512816 | 152113811 | 152114008 | 152113817 | 152113817 | Frame_Shift_Del | G | - | p.L437fs |
| UCEC | TCGA-B5-A0K2-01 | exon_skip_512819 | 152128243 | 152128440 | 152128422 | 152128423 | Frame_Shift_Del | GA | - | p.R561fs |
| UCEC | TCGA-B5-A0K2-01 | exon_skip_512819 | 152128243 | 152128440 | 152128422 | 152128423 | Frame_Shift_Del | GA | - | p.S531fs |
| UCEC | TCGA-B5-A0K2-01 | exon_skip_512821 | 152128243 | 152128481 | 152128422 | 152128423 | Frame_Shift_Del | GA | - | p.R561fs |
| UCEC | TCGA-B5-A0K2-01 | exon_skip_512821 | 152128243 | 152128481 | 152128422 | 152128423 | Frame_Shift_Del | GA | - | p.S531fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_512824 | 152132383 | 152132493 | 152132452 | 152132452 | Frame_Shift_Del | T | - | p.Y590fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_512830 | 152138987 | 152139085 | 152138994 | 152138994 | Frame_Shift_Del | T | - | p.I692fs |
| COAD | TCGA-G4-6299-01 | exon_skip_512790 exon_skip_512789 | 152090717 | 152090800 | 152090757 | 152090757 | Nonsense_Mutation | C | T | p.Q232X |
| LIHC | TCGA-G3-A3CG-01 | exon_skip_512816 | 152113811 | 152114008 | 152113989 | 152113989 | Nonsense_Mutation | C | T | p.R495X |
| KICH | TCGA-KL-8331-01 | exon_skip_512793 exon_skip_512792 | 152091264 | 152091353 | 152091354 | 152091354 | Splice_Site | G | T | . |
| KICH | TCGA-KL-8331-01 | exon_skip_512793 exon_skip_512792 | 152091264 | 152091353 | 152091354 | 152091354 | Splice_Site | G | T | p.S276_splice |
| OV | TCGA-24-1436-01 | exon_skip_512830 | 152138987 | 152139085 | 152138985 | 152138985 | Splice_Site | A | G | e22-2 |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| MCAS_OVARY | 152113811 | 152114008 | 152113846 | 152113846 | Frame_Shift_Del | C | - | p.T415fs |
| HCC2450_LUNG | 152090717 | 152090800 | 152090787 | 152090787 | Missense_Mutation | C | G | p.P242A |
| HEC59_ENDOMETRIUM | 152091264 | 152091353 | 152091334 | 152091334 | Missense_Mutation | G | A | p.A270T |
| SNU1040_LARGE_INTESTINE | 152097119 | 152097205 | 152097142 | 152097142 | Missense_Mutation | G | A | p.R284H |
| SUDHL16_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 152097119 | 152097205 | 152097142 | 152097142 | Missense_Mutation | G | A | p.R284H |
| BICR10_UPPER_AERODIGESTIVE_TRACT | 152097119 | 152097205 | 152097145 | 152097145 | Missense_Mutation | T | C | p.L285P |
| COV644_OVARY | 152097119 | 152097205 | 152097149 | 152097149 | Missense_Mutation | G | C | p.Q286H |
| SKUT1_SOFT_TISSUE | 152097119 | 152097205 | 152097175 | 152097175 | Missense_Mutation | G | A | p.R295H |
| CW2_LARGE_INTESTINE | 152101417 | 152101515 | 152101421 | 152101421 | Missense_Mutation | A | G | p.S342G |
| SW1116_LARGE_INTESTINE | 152106618 | 152106707 | 152106650 | 152106650 | Missense_Mutation | C | A | p.A384D |
| SISO_CERVIX | 152113811 | 152114008 | 152113854 | 152113854 | Missense_Mutation | G | A | p.G418R |
| GRST_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 152113811 | 152114008 | 152113854 | 152113854 | Missense_Mutation | G | A | p.G418R |
| HCT15_LARGE_INTESTINE | 152113811 | 152114008 | 152113909 | 152113909 | Missense_Mutation | C | A | p.A436D |
| MFE296_ENDOMETRIUM | 152128243 | 152128440 | 152128368 | 152128368 | Missense_Mutation | C | A | p.P511H |
| MFE296_ENDOMETRIUM | 152128243 | 152128481 | 152128368 | 152128368 | Missense_Mutation | C | A | p.P511H |
| SW962_VULVA | 152128243 | 152128440 | 152128400 | 152128400 | Missense_Mutation | G | A | p.G522R |
| SW962_VULVA | 152128243 | 152128481 | 152128400 | 152128400 | Missense_Mutation | G | A | p.G522R |
| COLO792_SKIN | 152128243 | 152128440 | 152128422 | 152128422 | Missense_Mutation | G | A | p.R529Q |
| COLO792_SKIN | 152128243 | 152128481 | 152128422 | 152128422 | Missense_Mutation | G | A | p.R529Q |
| KMS34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 152132383 | 152132493 | 152132471 | 152132471 | Missense_Mutation | G | A | p.E565K |
| NCIH1838_LUNG | 152138987 | 152139085 | 152139042 | 152139042 | Missense_Mutation | G | T | p.R676L |
| PECAPJ15_UPPER_AERODIGESTIVE_TRACT | 152138987 | 152139085 | 152139053 | 152139053 | Missense_Mutation | C | T | p.H680Y |
| GP5D_LARGE_INTESTINE | 152138987 | 152139085 | 152139059 | 152139059 | Missense_Mutation | G | A | p.G682R |
| SW13_ADRENAL_CORTEX | 152128243 | 152128440 | 152128404 | 152128405 | Nonsense_Mutation | CT | AA | p.S523* |
| SW13_ADRENAL_CORTEX | 152128243 | 152128481 | 152128404 | 152128405 | Nonsense_Mutation | CT | AA | p.S523* |
| COLO679_SKIN | 152088872 | 152088955 | 152088954 | 152088954 | Splice_Site | G | T | p.G205C |
Top |
Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ZNF185 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
Top |
Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZNF185 |
Top |
Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZNF185 |
Top |
RelatedDrugs for ZNF185 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ZNF185 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|