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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in TCGA

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Exon skipping events with PSIs in GTEx

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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SNVs in the skipped exons with depth of coverage

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

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Related drugs with this gene

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Related diseases with this gene

Gene summary for TP53BP1

check button Gene summary
Gene informationGene symbol

TP53BP1

Gene ID

7158

Gene nametumor protein p53 binding protein 1
Synonyms53BP1|TDRD30|TP53|p202|p53BP1
Cytomap

15q15.3

Type of geneprotein-coding
DescriptionTP53-binding protein 1p53-binding protein 1tumor protein 53-binding protein, 1tumor suppressor p53-binding protein 1
Modification date20180527
UniProtAcc

Q12888

ContextPubMed: TP53BP1 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
TP53BP1

GO:0006303

double-strand break repair via nonhomologous end joining

23333306|23760478|28241136

TP53BP1

GO:0006974

cellular response to DNA damage stimulus

17500065|28241136

TP53BP1

GO:0045830

positive regulation of isotype switching

23345425

TP53BP1

GO:0051260

protein homooligomerization

23345425

TP53BP1

GO:2000042

negative regulation of double-strand break repair via homologous recombination

23333306|23345425


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Exon skipping events across known transcript of Ensembl for TP53BP1 from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Gene isoform structures and expression levels for TP53BP1

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


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Exon skipping events with PSIs in TCGA for TP53BP1

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_1264881543699413:43699768:43700140:43700286:43701094:4370129443700140:43700286ENSG00000067369.9ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000382039.3,ENST00000476454.1,ENST00000411772.1
exon_skip_1264901543701844:43701939:43704869:43704965:43705316:4370548443704869:43704965ENSG00000067369.9ENST00000434595.1
exon_skip_1264911543701844:43701939:43705316:43705526:43707791:4370800743705316:43705526ENSG00000067369.9ENST00000450115.2
exon_skip_1264921543701844:43701939:43705316:43705532:43707791:4370800743705316:43705532ENSG00000067369.9ENST00000382044.4,ENST00000263801.3,ENST00000382039.3,ENST00000476454.1,ENST00000411772.1
exon_skip_1264941543705466:43705532:43706245:43706314:43707791:4370800743706245:43706314ENSG00000067369.9ENST00000434561.1
exon_skip_1264971543712815:43712933:43713222:43713372:43714052:4371432443713222:43713372ENSG00000067369.9ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000411772.1
exon_skip_1264991543720213:43720366:43724391:43724875:43730521:4373060543724391:43724875ENSG00000067369.9ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000382039.3,ENST00000411772.1
exon_skip_1265011543724846:43724875:43730521:43730614:43733723:4373378143730521:43730614ENSG00000067369.9ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000413546.1,ENST00000382039.3,ENST00000411772.1
exon_skip_1265021543730521:43730614:43733723:43733781:43738584:4373878843733723:43733781ENSG00000067369.9ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000413546.1,ENST00000382039.3,ENST00000411772.1
exon_skip_1265031543733723:43733781:43738584:43738788:43748089:4374822243738584:43738788ENSG00000067369.9ENST00000413546.1
exon_skip_1265061543738730:43738788:43738963:43739108:43739563:4373968343738963:43739108ENSG00000067369.9ENST00000605155.1
exon_skip_1265071543738730:43738788:43738963:43739112:43739563:4373968343738963:43739112ENSG00000067369.9ENST00000411772.1
exon_skip_1265091543738730:43738788:43739563:43739683:43748089:4374822243739563:43739683ENSG00000067369.9ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000382039.3
exon_skip_1265101543739563:43739683:43748089:43749416:43762055:4376226443748089:43749416ENSG00000067369.9ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000382039.3
exon_skip_1265111543762055:43762264:43766870:43766965:43767762:4376789243766870:43766965ENSG00000067369.9ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000413546.1,ENST00000382039.3
exon_skip_1265131543772056:43772215:43773092:43773220:43783866:4378395143773092:43773220ENSG00000067369.9ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000413546.1,ENST00000382039.3

check button PSI values of skipped exons in TCGA.
psi tcga

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Exon skipping events with PSIs in GTEx for TP53BP1

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_1264881543699413:43699768:43700140:43700286:43701094:4370129443700140:43700286ENSG00000067369.9ENST00000263801.3,ENST00000476454.1,ENST00000411772.1,ENST00000382039.3,ENST00000382044.4,ENST00000450115.2
exon_skip_1264901543701844:43701939:43704869:43704965:43705316:4370548443704869:43704965ENSG00000067369.9ENST00000434595.1
exon_skip_1264911543701844:43701939:43705316:43705526:43707791:4370800743705316:43705526ENSG00000067369.9ENST00000450115.2
exon_skip_1264921543701844:43701939:43705316:43705532:43707791:4370800743705316:43705532ENSG00000067369.9ENST00000263801.3,ENST00000476454.1,ENST00000411772.1,ENST00000382039.3,ENST00000382044.4
exon_skip_1264941543705466:43705532:43706245:43706314:43707791:4370800743706245:43706314ENSG00000067369.9ENST00000434561.1
exon_skip_1264971543712815:43712933:43713222:43713372:43714052:4371432443713222:43713372ENSG00000067369.9ENST00000263801.3,ENST00000411772.1,ENST00000382044.4,ENST00000450115.2,ENST00000572085.1
exon_skip_1264991543720213:43720366:43724391:43724875:43730521:4373060543724391:43724875ENSG00000067369.9ENST00000263801.3,ENST00000411772.1,ENST00000382039.3,ENST00000382044.4,ENST00000450115.2,ENST00000572085.1
exon_skip_1265011543724846:43724875:43730521:43730614:43733723:4373378143730521:43730614ENSG00000067369.9ENST00000263801.3,ENST00000411772.1,ENST00000382039.3,ENST00000382044.4,ENST00000450115.2,ENST00000572085.1,ENST00000413546.1
exon_skip_1265021543730521:43730614:43733723:43733781:43738584:4373878843733723:43733781ENSG00000067369.9ENST00000263801.3,ENST00000411772.1,ENST00000382039.3,ENST00000382044.4,ENST00000450115.2,ENST00000572085.1,ENST00000413546.1
exon_skip_1265031543733723:43733781:43738584:43738788:43748089:4374822243738584:43738788ENSG00000067369.9ENST00000413546.1
exon_skip_1265061543738730:43738788:43738963:43739108:43739563:4373968343738963:43739108ENSG00000067369.9ENST00000605155.1
exon_skip_1265071543738730:43738788:43738963:43739112:43739563:4373968343738963:43739112ENSG00000067369.9ENST00000411772.1
exon_skip_1265091543738730:43738788:43739563:43739683:43748089:4374822243739563:43739683ENSG00000067369.9ENST00000263801.3,ENST00000382039.3,ENST00000382044.4,ENST00000450115.2,ENST00000572085.1
exon_skip_1265101543739563:43739683:43748089:43749416:43762055:4376226443748089:43749416ENSG00000067369.9ENST00000263801.3,ENST00000382039.3,ENST00000382044.4,ENST00000450115.2,ENST00000572085.1
exon_skip_1265111543762055:43762264:43766870:43766965:43767762:4376789243766870:43766965ENSG00000067369.9ENST00000263801.3,ENST00000382039.3,ENST00000382044.4,ENST00000450115.2,ENST00000572085.1,ENST00000413546.1
exon_skip_1265131543772056:43772215:43773092:43773220:43783866:4378395143773092:43773220ENSG00000067369.9ENST00000263801.3,ENST00000382039.3,ENST00000382044.4,ENST00000450115.2,ENST00000572085.1,ENST00000413546.1

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for TP53BP1

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000002638014370014043700286Frame-shift
ENST000002638014372439143724875Frame-shift
ENST000002638014373372343733781Frame-shift
ENST000002638014374808943749416Frame-shift
ENST000002638014376687043766965Frame-shift
ENST000002638014377309243773220Frame-shift
ENST000002638014370531643705532In-frame
ENST000002638014371322243713372In-frame
ENST000002638014373052143730614In-frame
ENST000002638014373956343739683In-frame

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000002638014370014043700286Frame-shift
ENST000002638014372439143724875Frame-shift
ENST000002638014373372343733781Frame-shift
ENST000002638014374808943749416Frame-shift
ENST000002638014376687043766965Frame-shift
ENST000002638014377309243773220Frame-shift
ENST000002638014370531643705532In-frame
ENST000002638014371322243713372In-frame
ENST000002638014373052143730614In-frame
ENST000002638014373956343739683In-frame

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Infer the effects of exon skipping event on protein functional features for TP53BP1

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000026380163631972437395634373968329553074900940
ENST000002638016363197243730521437306143337342910281058
ENST000002638016363197243713222437133724339448813621411
ENST000002638016363197243705316437055325328554316911763

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000026380163631972437395634373968329553074900940
ENST000002638016363197243730521437306143337342910281058
ENST000002638016363197243713222437133724339448813621411
ENST000002638016363197243705316437055325328554316911763

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q1288890094011972ChainID=PRO_0000072643;Note=TP53-binding protein 1
Q12888900940930930Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:25218447,ECO:0000244|PubMed:25772364,ECO:0000244|PubMed:28112733;Dbxref=PMID:25218447,PMID:25772364,PMI
Q12888900940922922Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:20068231,PMID:23186163
Q128881028105811972ChainID=PRO_0000072643;Note=TP53-binding protein 1
Q128881028105810281028Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000269;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
Q128881028105810561056Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
Q128881362141111972ChainID=PRO_0000072643;Note=TP53-binding protein 1
Q128881362141113651365Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:28112733;Dbxref=PMID:28112733
Q128881362141113621362Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,ECO:0000244|PubMed:24275569;Dbxref=PMID:1
Q128881362141113681368Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
Q128881362141113721372Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
Q128881362141113961403MotifNote=GAR;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16294045;Dbxref=PMID:16294045
Q128881362141113961396MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). Loss of methylation%3B when associated with A-1398%3B A-1400%3B A-1401 and A-1403. R->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Db
Q128881362141113961396MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). R->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Dbxref=PMID:16294045,PMID:16294047
Q128881362141113981401MutagenesisNote=No effect on in class-switch recombination (CSR). RGRR->AGAA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23345425;Dbxref=PMID:23345425
Q128881362141113981398MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). Loss of methylation%3B when associated with A-1396%3B A-1400%3B A-1401 and A-1403. R->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Db
Q128881362141113981398MutagenesisNote=Reduced methylation by PRMT1 (in vitro). Strongly reduced methylation%3B when associated with K-1400. Strongly reduced methylation%3B when associated with K-1401. R->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:000
Q128881362141114001400MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). Loss of methylation%3B when associated with A-1396%3B A-1398%3B A-1401 and A-1403. R->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Db
Q128881362141114001400MutagenesisNote=Reduced methylation by PRMT1 (in vitro). Strongly reduced methylation%3B when associated with K-1398. Strongly reduced methylation%3B when associated with K-1401. R->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:000
Q128881362141114011401MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). Loss of methylation%3B when associated with A-1396%3B A-1398%3B A-1400 and A-1403. R->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Db
Q128881362141114011401MutagenesisNote=Reduced methylation by PRMT1 (in vitro). Strongly reduced methylation%3B when associated with K-1398. Strongly reduced methylation%3B when associated with K-1400. R->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:000
Q128881362141114031403MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). Loss of methylation%3B when associated with A-1396%3B A-1398%3B A-1400 and A-1401. R->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Db
Q128881362141114031403MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). R->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Dbxref=PMID:16294045,PMID:16294047
Q128881691176316921693Alternative sequenceID=VSP_055062;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.2
Q128881691176317321736Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1KZY
Q128881691176311972ChainID=PRO_0000072643;Note=TP53-binding protein 1
Q128881691176317601764Compositional biasNote=Poly-Glu
Q128881691176317241848DomainNote=BRCT 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00033
Q128881691176317151719HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1KZY
Q128881691176317411745HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1GZH
Q128881691176317011701Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:23186163
Q128881691176317591759Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
Q128881691176317261731TurnOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1KZY


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q1288890094011972ChainID=PRO_0000072643;Note=TP53-binding protein 1
Q12888900940930930Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:25218447,ECO:0000244|PubMed:25772364,ECO:0000244|PubMed:28112733;Dbxref=PMID:25218447,PMID:25772364,PMI
Q12888900940922922Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:20068231,PMID:23186163
Q128881028105811972ChainID=PRO_0000072643;Note=TP53-binding protein 1
Q128881028105810281028Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000269;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
Q128881028105810561056Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
Q128881362141111972ChainID=PRO_0000072643;Note=TP53-binding protein 1
Q128881362141113651365Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:28112733;Dbxref=PMID:28112733
Q128881362141113621362Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,ECO:0000244|PubMed:24275569;Dbxref=PMID:1
Q128881362141113681368Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
Q128881362141113721372Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
Q128881362141113961403MotifNote=GAR;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16294045;Dbxref=PMID:16294045
Q128881362141113961396MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). Loss of methylation%3B when associated with A-1398%3B A-1400%3B A-1401 and A-1403. R->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Db
Q128881362141113961396MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). R->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Dbxref=PMID:16294045,PMID:16294047
Q128881362141113981401MutagenesisNote=No effect on in class-switch recombination (CSR). RGRR->AGAA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23345425;Dbxref=PMID:23345425
Q128881362141113981398MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). Loss of methylation%3B when associated with A-1396%3B A-1400%3B A-1401 and A-1403. R->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Db
Q128881362141113981398MutagenesisNote=Reduced methylation by PRMT1 (in vitro). Strongly reduced methylation%3B when associated with K-1400. Strongly reduced methylation%3B when associated with K-1401. R->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:000
Q128881362141114001400MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). Loss of methylation%3B when associated with A-1396%3B A-1398%3B A-1401 and A-1403. R->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Db
Q128881362141114001400MutagenesisNote=Reduced methylation by PRMT1 (in vitro). Strongly reduced methylation%3B when associated with K-1398. Strongly reduced methylation%3B when associated with K-1401. R->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:000
Q128881362141114011401MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). Loss of methylation%3B when associated with A-1396%3B A-1398%3B A-1400 and A-1403. R->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Db
Q128881362141114011401MutagenesisNote=Reduced methylation by PRMT1 (in vitro). Strongly reduced methylation%3B when associated with K-1398. Strongly reduced methylation%3B when associated with K-1400. R->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:000
Q128881362141114031403MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). Loss of methylation%3B when associated with A-1396%3B A-1398%3B A-1400 and A-1401. R->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Db
Q128881362141114031403MutagenesisNote=No detectable effect on methylation by PRMT1 (in vitro). R->K;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16294045,ECO:0000269|PubMed:16294047;Dbxref=PMID:16294045,PMID:16294047
Q128881691176316921693Alternative sequenceID=VSP_055062;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.2
Q128881691176317321736Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1KZY
Q128881691176311972ChainID=PRO_0000072643;Note=TP53-binding protein 1
Q128881691176317601764Compositional biasNote=Poly-Glu
Q128881691176317241848DomainNote=BRCT 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00033
Q128881691176317151719HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1KZY
Q128881691176317411745HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1GZH
Q128881691176317011701Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:23186163
Q128881691176317591759Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
Q128881691176317261731TurnOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1KZY


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SNVs in the skipped exons for TP53BP1

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.
TP53BP1_ESCA_exon_skip_126510_psi_boxplot.png
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TP53BP1_LIHC_exon_skip_126510_psi_boxplot.png
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TP53BP1_SKCM_exon_skip_126510_psi_boxplot.png
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TP53BP1_STAD_exon_skip_126510_psi_boxplot.png
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check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
CESCTCGA-IR-A3LB-01exon_skip_126488
43700141437002864370021943700219Frame_Shift_DelG-p.L1890fs
HNSCTCGA-CV-A464-01exon_skip_126497
43713223437133724371334243713345Frame_Shift_DelCGTC-p.GT1371fs
LIHCTCGA-DD-A3A0-01exon_skip_126497
43713223437133724371334543713345Frame_Shift_DelC-p.G1371fs
LIHCTCGA-DD-A3A0-01exon_skip_126497
43713223437133724371336343713363Frame_Shift_DelT-p.K1365fs
STADTCGA-BR-7707-01exon_skip_126499
43724392437248754372441843724418Frame_Shift_DelC-p.D1217fs
KIRCTCGA-BP-5004-01exon_skip_126499
43724392437248754372466843724668Frame_Shift_DelC-p.K1134fs
KIRCTCGA-BP-5004-01exon_skip_126499
43724392437248754372466843724668Frame_Shift_DelC-p.Q1128fs
LUADTCGA-86-8669-01exon_skip_126501
43730522437306144373056643730582Frame_Shift_DelTTGCCTGGCTTCACAGA-p.ICEARQ1039fs
LIHCTCGA-DD-A39Y-01exon_skip_126502
43733724437337814373375743733757Frame_Shift_DelT-p.N1017fs
PRADTCGA-KK-A59V-01exon_skip_126502
43733724437337814373375743733757Frame_Shift_DelT-p.N1017fs
PRADTCGA-KK-A59V-01exon_skip_126502
43733724437337814373375743733757Frame_Shift_DelT-p.N1022fs
STADTCGA-CG-5721-01exon_skip_126502
43733724437337814373375743733757Frame_Shift_DelT-p.N1017fs
STADTCGA-CG-5721-01exon_skip_126502
43733724437337814373375743733757Frame_Shift_DelT-p.N1022fs
STADTCGA-HU-A4GN-01exon_skip_126502
43733724437337814373375743733757Frame_Shift_DelT-p.N1017fs
STADTCGA-HU-A4GN-01exon_skip_126502
43733724437337814373375743733757Frame_Shift_DelT-p.N1022fs
LIHCTCGA-DD-A39Y-01exon_skip_126509
43739564437396834373959543739595Frame_Shift_DelT-p.K930fs
STADTCGA-BR-4368-01exon_skip_126510
43748090437494164374829743748297Frame_Shift_DelG-p.Q832fs
STADTCGA-BR-4368-01exon_skip_126510
43748090437494164374829743748297Frame_Shift_DelG-p.Q837fs
STADTCGA-CG-5723-01exon_skip_126510
43748090437494164374830343748304Frame_Shift_DelAA-p.835_835del
STADTCGA-CG-5723-01exon_skip_126510
43748090437494164374830343748304Frame_Shift_DelAA-p.S830fs
STADTCGA-BR-4201-01exon_skip_126510
43748090437494164374842943748448Frame_Shift_DelCCCATGACTGGGAATCTGAG-p.S782fs
LIHCTCGA-DD-A3A0-01exon_skip_126510
43748090437494164374860843748608Frame_Shift_DelG-p.P728fs
LIHCTCGA-DD-A39Y-01exon_skip_126510
43748090437494164374866143748661Frame_Shift_DelT-p.K710fs
STADTCGA-BR-4280-01exon_skip_126510
43748090437494164374866143748661Frame_Shift_DelT-p.E711fs
STADTCGA-BR-4280-01exon_skip_126510
43748090437494164374866143748661Frame_Shift_DelT-p.E716fs
STADTCGA-HU-A4G8-01exon_skip_126510
43748090437494164374866143748661Frame_Shift_DelT-p.E711fs
STADTCGA-HU-A4G8-01exon_skip_126510
43748090437494164374866143748661Frame_Shift_DelT-p.E716fs
UCECTCGA-A5-A0GH-01exon_skip_126510
43748090437494164374926043749260Frame_Shift_DelC-p.D511fs
PRADTCGA-EJ-7786-01exon_skip_126510
43748090437494164374818543748186Frame_Shift_Ins-Tp.M869fs
COADTCGA-A6-5665-01exon_skip_126510
43748090437494164374866043748661Frame_Shift_Ins-Tp.E711fs
LIHCTCGA-BC-A112-01exon_skip_126510
43748090437494164374881643748817Frame_Shift_Ins-Cp.F659fs
CHOLTCGA-ZH-A8Y8-01exon_skip_126511
43766871437669654376690943766910Frame_Shift_Ins-Tp.I381fs
CHOLTCGA-ZH-A8Y8-01exon_skip_126511
43766871437669654376690943766910Frame_Shift_Ins-Tp.R376fs
UCECTCGA-AP-A051-01exon_skip_126503
43738585437387884373860943738609Nonsense_MutationCAp.E1006*
KIRCTCGA-B0-5096-01exon_skip_126510
43748090437494164374816143748161Nonsense_MutationGCp.S877*
KIRCTCGA-B0-5096-01exon_skip_126510
43748090437494164374816143748161Nonsense_MutationGCp.S882X
KIRCTCGA-CZ-5459-01exon_skip_126510
43748090437494164374819143748191Nonsense_MutationGTp.S872X
KIRPTCGA-P4-A5E8-01exon_skip_126510
43748090437494164374823743748237Nonsense_MutationGAp.Q852*
KIRPTCGA-P4-A5E8-01exon_skip_126510
43748090437494164374823743748237Nonsense_MutationGAp.Q852X
KIRPTCGA-P4-A5E8-01exon_skip_126510
43748090437494164374823743748237Nonsense_MutationGAp.Q857X
UCECTCGA-AP-A056-01exon_skip_126510
43748090437494164374858243748582Nonsense_MutationCAp.E742*
UCECTCGA-BG-A0M7-01exon_skip_126510
43748090437494164374864243748642Nonsense_MutationCAp.E717*
PRADTCGA-G9-6338-01exon_skip_126510
43748090437494164374875343748753Nonsense_MutationTAp.K680*
PRADTCGA-G9-6338-01exon_skip_126510
43748090437494164374875343748753Nonsense_MutationTAp.K685X
HNSCTCGA-CV-A463-01exon_skip_126510
43748090437494164374885543748855Nonsense_MutationCAp.E646*
SKCMTCGA-3N-A9WC-06exon_skip_126510
43748090437494164374886143748861Nonsense_MutationGAp.Q644*
SKCMTCGA-EE-A29H-06exon_skip_126510
43748090437494164374889143748891Nonsense_MutationGAp.R634*
SKCMTCGA-EE-A29H-06exon_skip_126510
43748090437494164374889143748891Nonsense_MutationGAp.R634X
ESCATCGA-L5-A8NM-01exon_skip_126510
43748090437494164374896943748969Nonsense_MutationCAp.E608*
ESCATCGA-L5-A8NM-01exon_skip_126510
43748090437494164374896943748969Nonsense_MutationCAp.E613*
ESCATCGA-L5-A8NM-01exon_skip_126510
43748090437494164374896943748969Nonsense_MutationCAp.E613X
UCECTCGA-D1-A103-01exon_skip_126513
43773093437732204377316543773165Nonsense_MutationCAp.E143*
GBMTCGA-06-0185-01exon_skip_126513
43773093437732204377322143773221Splice_SiteCGp.S119_splice

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description
TP53BP1_43739563_43739683_43748089_43749416_43762055_43762264_TCGA-L5-A8NM-01Sample: TCGA-L5-A8NM-01
Cancer type: ESCA
ESID: exon_skip_126510
Skipped exon start: 43748090
Skipped exon end: 43749416
Mutation start: 43748969
Mutation end: 43748969
Mutation type: Nonsense_Mutation
Reference seq: C
Mutation seq: A
AAchange: p.E613X
TP53BP1_43739563_43739683_43748089_43749416_43762055_43762264_TCGA-L5-A8NM-01Sample: TCGA-L5-A8NM-01
Cancer type: ESCA
ESID: exon_skip_126510
Skipped exon start: 43748090
Skipped exon end: 43749416
Mutation start: 43748969
Mutation end: 43748969
Mutation type: Nonsense_Mutation
Reference seq: C
Mutation seq: A
AAchange: p.E608*
TP53BP1_43739563_43739683_43748089_43749416_43762055_43762264_TCGA-L5-A8NM-01Sample: TCGA-L5-A8NM-01
Cancer type: ESCA
ESID: exon_skip_126510
Skipped exon start: 43748090
Skipped exon end: 43749416
Mutation start: 43748969
Mutation end: 43748969
Mutation type: Nonsense_Mutation
Reference seq: C
Mutation seq: A
AAchange: p.E613*
exon_skip_126510_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_145922_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_20931_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_290909_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_301129_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_308211_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_308974_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_310302_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_329666_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_330701_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_330704_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_356820_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_356824_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_370065_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_389081_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_421270_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_433436_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_461351_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_461353_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_464726_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_47552_ESCA_TCGA-L5-A8NM-01.png
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exon_skip_517614_ESCA_TCGA-L5-A8NM-01.png
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TP53BP1_43739563_43739683_43748089_43749416_43762055_43762264_TCGA-BR-4280-01Sample: TCGA-BR-4280-01
Cancer type: STAD
ESID: exon_skip_126510
Skipped exon start: 43748090
Skipped exon end: 43749416
Mutation start: 43748661
Mutation end: 43748661
Mutation type: Frame_Shift_Del
Reference seq: T
Mutation seq: -
AAchange: p.E716fs
TP53BP1_43739563_43739683_43748089_43749416_43762055_43762264_TCGA-BR-4280-01Sample: TCGA-BR-4280-01
Cancer type: STAD
ESID: exon_skip_126510
Skipped exon start: 43748090
Skipped exon end: 43749416
Mutation start: 43748661
Mutation end: 43748661
Mutation type: Frame_Shift_Del
Reference seq: T
Mutation seq: -
AAchange: p.E711fs
exon_skip_126510_STAD_TCGA-BR-4280-01.png
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exon_skip_363720_STAD_TCGA-BR-4280-01.png
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TP53BP1_43739563_43739683_43748089_43749416_43762055_43762264_TCGA-BR-4368-01Sample: TCGA-BR-4368-01
Cancer type: STAD
ESID: exon_skip_126510
Skipped exon start: 43748090
Skipped exon end: 43749416
Mutation start: 43748297
Mutation end: 43748297
Mutation type: Frame_Shift_Del
Reference seq: G
Mutation seq: -
AAchange: p.Q837fs
TP53BP1_43739563_43739683_43748089_43749416_43762055_43762264_TCGA-BR-4368-01Sample: TCGA-BR-4368-01
Cancer type: STAD
ESID: exon_skip_126510
Skipped exon start: 43748090
Skipped exon end: 43749416
Mutation start: 43748297
Mutation end: 43748297
Mutation type: Frame_Shift_Del
Reference seq: G
Mutation seq: -
AAchange: p.Q832fs
exon_skip_113437_STAD_TCGA-BR-4368-01.png
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exon_skip_121036_STAD_TCGA-BR-4368-01.png
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exon_skip_126510_STAD_TCGA-BR-4368-01.png
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exon_skip_309996_STAD_TCGA-BR-4368-01.png
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exon_skip_384879_STAD_TCGA-BR-4368-01.png
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exon_skip_425876_STAD_TCGA-BR-4368-01.png
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exon_skip_491897_STAD_TCGA-BR-4368-01.png
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check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
ES8_BONE43705317437055264370539043705390Frame_Shift_DelG-p.A1739fs
ES8_BONE43705317437055324370539043705390Frame_Shift_DelG-p.A1739fs
NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE43713223437133724371333243713333Frame_Shift_DelCA-p.CE1375fs
22RV1_PROSTATE43730522437306144373053643730536Frame_Shift_DelG-p.P1054fs
HEC59_ENDOMETRIUM43730522437306144373053643730536Frame_Shift_DelG-p.P1054fs
2313287_STOMACH43730522437306144373053643730536Frame_Shift_DelG-p.P1054fs
SKUT1_SOFT_TISSUE43730522437306144373053643730536Frame_Shift_DelG-p.P1054fs
DG75_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE43730522437306144373053643730536Frame_Shift_DelG-p.P1054fs
VMRCLCD_LUNG43738585437387884373865043738663Frame_Shift_DelAGACATAATTTATC-p.DKLCL983fs
LS411N_LARGE_INTESTINE43748090437494164374818643748186Frame_Shift_DelT-p.M869fs
C33A_CERVIX43748090437494164374866143748661Frame_Shift_DelT-p.K710fs
CMLT1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE43748090437494164374866143748661Frame_Shift_DelT-p.K710fs
DV90_LUNG43748090437494164374866143748661Frame_Shift_DelT-p.K710fs
SNU349_KIDNEY43748090437494164374866143748661Frame_Shift_DelT-p.K710fs
CW2_LARGE_INTESTINE43748090437494164374866143748661Frame_Shift_DelT-p.K710fs
CL34_LARGE_INTESTINE43748090437494164374940843749408Frame_Shift_DelA-p.F461fs
HEYA8_OVARY43713223437133724371334443713345Frame_Shift_Ins-Cp.T1372fs
HEY_OVARY43713223437133724371334443713345Frame_Shift_Ins-Cp.T1372fs
2313287_STOMACH43748090437494164374866043748661Frame_Shift_Ins-Tp.E711fs
SUDHL6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE43705317437055264370535043705350Missense_MutationCTp.D1753N
SUDHL6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE43705317437055324370535043705350Missense_MutationCTp.D1753N
BICR18_UPPER_AERODIGESTIVE_TRACT43705317437055264370535243705352Missense_MutationGAp.P1752L
BICR18_UPPER_AERODIGESTIVE_TRACT43705317437055324370535243705352Missense_MutationGAp.P1752L
HEC251_ENDOMETRIUM43705317437055264370537943705379Missense_MutationTCp.D1743G
HEC251_ENDOMETRIUM43705317437055324370537943705379Missense_MutationTCp.D1743G
HEC108_ENDOMETRIUM43705317437055264370543343705433Missense_MutationTCp.N1725S
HEC108_ENDOMETRIUM43705317437055324370543343705433Missense_MutationTCp.N1725S
2313287_STOMACH43705317437055264370552643705526Missense_MutationAGp.V1694A
2313287_STOMACH43705317437055324370552643705526Missense_MutationAGp.V1694A
SNU1040_LARGE_INTESTINE43713223437133724371326643713266Missense_MutationGAp.R1398C
HEYA8_OVARY43713223437133724371335443713354Missense_MutationACp.S1368R
HEY_OVARY43713223437133724371335443713354Missense_MutationACp.S1368R
BICR18_UPPER_AERODIGESTIVE_TRACT43713223437133724371335943713359Missense_MutationCTp.V1367I
CI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE43724392437248754372452043724520Missense_MutationATp.C1178S
COLO684_ENDOMETRIUM43724392437248754372465843724658Missense_MutationGAp.R1132W
COLO704_OVARY43724392437248754372465843724658Missense_MutationGAp.R1132W
WM1799_SKIN43724392437248754372485643724856Missense_MutationGTp.P1066T
HEC108_ENDOMETRIUM43724392437248754372487043724870Missense_MutationTCp.N1061S
SNU1040_LARGE_INTESTINE43730522437306144373055243730552Missense_MutationCTp.R1049Q
SNU81_LARGE_INTESTINE43738585437387884373862443738624Missense_MutationTCp.T996A
BT483_BREAST43738585437387884373862743738627Missense_MutationCGp.E995Q
MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE43739564437396834373957543739575Missense_MutationCTp.S937N
HCC38_BREAST43748090437494164374817443748174Missense_MutationTCp.K873E
HCC38_MATCHED_NORMAL_TISSUE43748090437494164374817443748174Missense_MutationTCp.K873E
HEC251_ENDOMETRIUM43748090437494164374836743748367Missense_MutationCAp.K808N
HEC59_ENDOMETRIUM43748090437494164374842543748425Missense_MutationTCp.D789G
SARC9371_BONE43748090437494164374844643748446Missense_MutationGAp.S782L
HEC251_ENDOMETRIUM43748090437494164374851543748515Missense_MutationAGp.V759A
HCC2998_LARGE_INTESTINE43748090437494164374866143748661Missense_MutationTGp.K710N
HEC6_ENDOMETRIUM43748090437494164374868443748684Missense_MutationGAp.L703F
HEC1_ENDOMETRIUM43748090437494164374876043748760Missense_MutationCAp.E677D
HEC1B_ENDOMETRIUM43748090437494164374876043748760Missense_MutationCAp.E677D
SNU201_CENTRAL_NERVOUS_SYSTEM43748090437494164374880443748804Missense_MutationCGp.E663Q
T3M10_LUNG43748090437494164374880943748809Missense_MutationCAp.G661V
HCC515_LUNG43748090437494164374899643748996Missense_MutationTCp.I599V
MDAMB361_BREAST43748090437494164374912143749121Missense_MutationGAp.S557F
SNU520_STOMACH43748090437494164374914343749143Missense_MutationGCp.P550A
NCIH1184_LUNG43748090437494164374915143749151Missense_MutationTCp.D547G
TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE43748090437494164374915843749158Missense_MutationTAp.I545F
SNU1040_LARGE_INTESTINE43748090437494164374924143749241Missense_MutationATp.L517H
TC71_BONE43748090437494164374924543749245Missense_MutationTAp.M516L
HEC59_ENDOMETRIUM43748090437494164374931743749317Missense_MutationTCp.T492A
SNU1040_LARGE_INTESTINE43748090437494164374935143749351Missense_MutationCTp.M480I
MDAMB453_BREAST43766871437669654376689243766892Missense_MutationTAp.T382S
JHUEM7_ENDOMETRIUM43766871437669654376692443766924Missense_MutationCTp.R371Q
SIMA_AUTONOMIC_GANGLIA43766871437669654376692443766924Missense_MutationCTp.R371Q
SUDHL1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE43773093437732204377311643773116Missense_MutationGAp.T154I
NCIH2286_LUNG43748090437494164374882243748822Nonsense_MutationCAp.E657*
HEC251_ENDOMETRIUM43748090437494164374882543748825Nonsense_MutationCAp.E656*

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for TP53BP1

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value
exon_skip_1264991543720213:43720366:43724391:43724875:43730521:4373060543724391:43724875ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000382039.3,ENST00000411772.1STADrs2602141chr15:43724646A/C1.02e-03
exon_skip_1264991543720213:43720366:43724391:43724875:43730521:4373060543724391:43724875ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000382039.3,ENST00000411772.1STADrs2602141chr15:43724646A/C1.54e-03
exon_skip_1265101543739563:43739683:43748089:43749416:43762055:4376226443748089:43749416ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000382039.3STADrs690367chr15:43748304C/T6.20e-04
exon_skip_1265101543739563:43739683:43748089:43749416:43762055:4376226443748089:43749416ENST00000572085.1,ENST00000450115.2,ENST00000382044.4,ENST00000263801.3,ENST00000382039.3STADrs690367chr15:43748304C/T9.64e-04

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for TP53BP1


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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for TP53BP1


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RelatedDrugs for TP53BP1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TP53BP1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource