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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for RPL37 |
 Gene summary |
| Gene information | Gene symbol | RPL37 | Gene ID | 6167 |
| Gene name | ribosomal protein L37 | |
| Synonyms | L37 | |
| Cytomap | 5p13.1 | |
| Type of gene | protein-coding | |
| Description | 60S ribosomal protein L3760S ribosomal protein L37aG1.16large ribosomal subunit protein eL37 | |
| Modification date | 20180523 | |
| UniProtAcc | P61927 | |
| Context | PubMed: RPL37 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for RPL37 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for RPL37 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for RPL37 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_441739 | 5 | 40827804:40828053:40831424:40831496:40832543:40832615 | 40831424:40831496 | ENSG00000145592.9 | ENST00000511787.1 |
| exon_skip_441756 | 5 | 40832559:40832675:40834282:40834367:40834572:40834655 | 40834282:40834367 | ENSG00000145592.9 | ENST00000504562.1,ENST00000274242.5 |
| exon_skip_441774 | 5 | 40834299:40834367:40834572:40834708:40835284:40835314 | 40834572:40834708 | ENSG00000145592.9 | ENST00000508493.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for RPL37 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_441739 | 5 | 40827804:40828053:40831424:40831496:40832543:40832615 | 40831424:40831496 | ENSG00000145592.9 | ENST00000511787.1 |
| exon_skip_441748 | 5 | 40832559:40832675:40834062:40834139:40834282:40834295 | 40834062:40834139 | ENSG00000145592.9 | ENST00000507642.1 |
| exon_skip_441756 | 5 | 40832559:40832675:40834282:40834367:40834572:40834655 | 40834282:40834367 | ENSG00000145592.9 | ENST00000274242.5,ENST00000504562.1 |
| exon_skip_441774 | 5 | 40834299:40834367:40834572:40834708:40835284:40835314 | 40834572:40834708 | ENSG00000145592.9 | ENST00000508493.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for RPL37 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000274242 | 40834282 | 40834367 | Frame-shift |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000274242 | 40834282 | 40834367 | Frame-shift |
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Infer the effects of exon skipping event on protein functional features for RPL37 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for RPL37 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| KIRC | TCGA-CJ-4636-01 | exon_skip_441774 | 40834573 | 40834708 | 40834595 | 40834596 | Frame_Shift_Ins | - | T | p.Y39_P40delinsX |
| LUAD | TCGA-86-8279-01 | exon_skip_441774 | 40834573 | 40834708 | 40834631 | 40834631 | Nonsense_Mutation | G | C | p.Y27* |
| HNSC | TCGA-CN-6013-01 | exon_skip_441774 | 40834573 | 40834708 | 40834692 | 40834692 | Nonsense_Mutation | G | T | p.S7* |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| SNU175_LARGE_INTESTINE | 40834283 | 40834367 | 40834312 | 40834312 | Missense_Mutation | C | A | p.R65S |
| HCT15_LARGE_INTESTINE | 40834283 | 40834367 | 40834337 | 40834337 | Missense_Mutation | T | G | p.N57T |
| OACM51_OESOPHAGUS | 40834573 | 40834708 | 40834590 | 40834590 | Missense_Mutation | G | A | p.A41V |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for RPL37 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for RPL37 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for RPL37 |
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RelatedDrugs for RPL37 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RPL37 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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