ExonSkipDB: functional annotation of exon skipping event in human

Gene summary for NSFL1C

Gene summary

Gene information	Gene symbol	NSFL1C
	Gene ID	55968
	Gene name	NSFL1 cofactor
	Synonyms	P47\|UBX1\|UBXD10\|UBXN2C\|dJ776F14.1
	Cytomap	20p13
	Type of gene	protein-coding
	Description	NSFL1 cofactor p47NSFL1 (p97) cofactor (p47)SHP1 homologUBX domain-containing protein 2Cp97 cofactor p47
	Modification date	20180523
	UniProtAcc	Q9UNZ2
	Context	PubMed: NSFL1C [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

Top

Exon skipping events across known transcript of Ensembl for NSFL1C from UCSC genome browser

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Top

Gene isoform structures and expression levels for NSFL1C

Expression levels of gene isoforms across TCGA.

Expression levels of gene isoforms across GTEx.

Top

Exon skipping events with PSIs in TCGA for NSFL1C

Information of exkip skipping event in TCGA.

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_354314	20	1424379:1424556:1426310:1426475:1433137:1433275	1426310:1426475	ENSG00000088833.13	ENST00000350991.4,ENST00000461211.1,ENST00000381658.4,ENST00000216879.4,ENST00000476071.1,ENST00000353088.2,ENST00000555944.1
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENSG00000088833.13	ENST00000381653.5
exon_skip_354319	20	1426310:1426475:1433137:1433275:1433675:1433785	1433137:1433275	ENSG00000088833.13	ENST00000555568.1,ENST00000350991.4,ENST00000461211.1,ENST00000381658.4,ENST00000216879.4,ENST00000476071.1,ENST00000353088.2,ENST00000555944.1
exon_skip_354321	20	1433764:1433785:1434857:1434950:1435611:1435682	1434857:1434950	ENSG00000088833.13	ENST00000555568.1,ENST00000350991.4,ENST00000381653.5,ENST00000461211.1,ENST00000470376.1,ENST00000381658.4,ENST00000216879.4,ENST00000476071.1,ENST00000555944.1,ENST00000553571.1
exon_skip_354328	20	1435611:1435777:1436358:1436364:1438844:1438919	1436358:1436364	ENSG00000088833.13	ENST00000476071.1
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENSG00000088833.13	ENST00000489203.2
exon_skip_354334	20	1438844:1438919:1443979:1444086:1444973:1445071	1443979:1444086	ENSG00000088833.13	ENST00000470376.1
exon_skip_354335	20	1438844:1438919:1444973:1445071:1447364:1447467	1444973:1445071	ENSG00000088833.13	ENST00000350991.4,ENST00000381653.5,ENST00000487086.1,ENST00000216879.4,ENST00000476071.1,ENST00000353088.2,ENST00000489203.2

PSI values of skipped exons in TCGA.

Top

Exon skipping events with PSIs in GTEx for NSFL1C

Information of exkip skipping event in GTEx

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_354314	20	1424379:1424556:1426310:1426475:1433137:1433275	1426310:1426475	ENSG00000088833.13	ENST00000461211.1,ENST00000353088.2,ENST00000555944.1,ENST00000476071.1,ENST00000216879.4,ENST00000381658.4,ENST00000350991.4
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENSG00000088833.13	ENST00000381653.5
exon_skip_354319	20	1426310:1426475:1433137:1433275:1433675:1433785	1433137:1433275	ENSG00000088833.13	ENST00000461211.1,ENST00000353088.2,ENST00000555944.1,ENST00000476071.1,ENST00000216879.4,ENST00000381658.4,ENST00000350991.4,ENST00000555568.1
exon_skip_354321	20	1433764:1433785:1434857:1434950:1435611:1435682	1434857:1434950	ENSG00000088833.13	ENST00000461211.1,ENST00000555944.1,ENST00000476071.1,ENST00000216879.4,ENST00000381658.4,ENST00000350991.4,ENST00000381653.5,ENST00000555568.1,ENST00000470376.1,ENST00000553571.1
exon_skip_354328	20	1435611:1435777:1436358:1436364:1438844:1438919	1436358:1436364	ENSG00000088833.13	ENST00000476071.1
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENSG00000088833.13	ENST00000489203.2
exon_skip_354334	20	1438844:1438919:1443979:1444086:1444973:1445071	1443979:1444086	ENSG00000088833.13	ENST00000470376.1
exon_skip_354335	20	1438844:1438919:1444973:1445071:1447364:1447467	1444973:1445071	ENSG00000088833.13	ENST00000353088.2,ENST00000476071.1,ENST00000216879.4,ENST00000350991.4,ENST00000381653.5,ENST00000489203.2,ENST00000487086.1

PSI values of skipped exons in GTEx.

* Skipped exon sequences.

Top

Open reading frame (ORF) annotation in the exon skipping event for NSFL1C

Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000216879	1444973	1445071	Frame-shift
ENST00000216879	1426310	1426475	In-frame
ENST00000216879	1433137	1433275	In-frame
ENST00000216879	1434857	1434950	In-frame

Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000216879	1444973	1445071	Frame-shift
ENST00000216879	1426310	1426475	In-frame
ENST00000216879	1433137	1433275	In-frame
ENST00000216879	1434857	1434950	In-frame

Top

Infer the effects of exon skipping event on protein functional features for NSFL1C

Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.

Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000216879	3585	370	1434857	1434950	1313	1405	148	179
ENST00000216879	3585	370	1433137	1433275	1516	1653	216	261
ENST00000216879	3585	370	1426310	1426475	1654	1818	262	316

Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000216879	3585	370	1434857	1434950	1313	1405	148	179
ENST00000216879	3585	370	1433137	1433275	1516	1653	216	261
ENST00000216879	3585	370	1426310	1426475	1654	1818	262	316

Lost protein functional features of individual exon skipping events in TCGA.

UniProt acc.

Start of exon skipping (AA)

End of exon skipping (AA)

Protein feature start (AA)

Protein feature end (AA)

Category of protein feature

Description of feature

Lost protein functional features of individual exon skipping events in GTEx.

UniProt acc.

Start of exon skipping (AA)

End of exon skipping (AA)

Protein feature start (AA)

Protein feature end (AA)

Category of protein feature

Description of feature

Top

SNVs in the skipped exons for NSFL1C

- Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.

- Differential PSIs between mutated versus non-mutated samples.

NSFL1C_LUAD_exon_skip_354315_psi_boxplot.png
boxplot

- Non-synonymous mutations located in the skipped exons in TCGA.

Cancer type	Sample	ESID	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
LIHC	TCGA-DD-A1EG-01	exon_skip_354321	1434858	1434950	1434880	1434880	Frame_Shift_Del	T	-	p.K172fs
LIHC	TCGA-BC-A3KG-01	exon_skip_354335	1444974	1445071	1445003	1445003	Frame_Shift_Del	G	-	p.P58fs
LIHC	TCGA-DD-A1EG-01	exon_skip_354335	1444974	1445071	1445003	1445003	Frame_Shift_Del	G	-	p.P58fs
LIHC	TCGA-G3-A3CJ-01	exon_skip_354335	1444974	1445071	1445017	1445017	Frame_Shift_Del	A	-	p.S54fs
STAD	TCGA-CD-A487-01	exon_skip_354314	1426311	1426475	1426464	1426465	Frame_Shift_Ins	-	G	p.Q266fs
STAD	TCGA-CD-A487-01	exon_skip_354315	1426311	1426794	1426464	1426465	Frame_Shift_Ins	-	G	p.Q266fs
STAD	TCGA-CD-A487-01	exon_skip_354314	1426311	1426475	1426465	1426466	Frame_Shift_Ins	-	G	p.Q266fs
STAD	TCGA-CD-A487-01	exon_skip_354315	1426311	1426794	1426465	1426466	Frame_Shift_Ins	-	G	p.Q266fs
UCEC	TCGA-B5-A0JY-01	exon_skip_354314	1426311	1426475	1426309	1426309	Splice_Site	A	G	e8+2
UCEC	TCGA-B5-A0JY-01	exon_skip_354315	1426311	1426794	1426309	1426309	Splice_Site	A	G	e8+2
LUAD	TCGA-78-7155-01	exon_skip_354314	1426311	1426475	1426310	1426310	Splice_Site	C	A	p.R317_splice
LUAD	TCGA-78-7155-01	exon_skip_354315	1426311	1426794	1426310	1426310	Splice_Site	C	A	p.R317_splice

- Depth of coverage in the three exons composing exon skipping event

Depth of coverage in three exons	Mutation description
	Sample: TCGA-78-7155-01
	Cancer type: LUAD
	ESID: exon_skip_354315
	Skipped exon start: 1426311
	Skipped exon end: 1426794
	Mutation start: 1426310
	Mutation end: 1426310
	Mutation type: Splice_Site
	Reference seq: C
	Mutation seq: A
	AAchange: p.R317_splice
	Sample: TCGA-78-7155-01
	Cancer type: LUAD
	ESID: exon_skip_354314
	Skipped exon start: 1426311
	Skipped exon end: 1426475
	Mutation start: 1426310
	Mutation end: 1426310
	Mutation type: Splice_Site
	Reference seq: C
	Mutation seq: A
	AAchange: p.R317_splice
exon_skip_330019_LUAD_TCGA-78-7155-01.png
exon_skip_347552_LUAD_TCGA-78-7155-01.png
exon_skip_348786_LUAD_TCGA-78-7155-01.png
exon_skip_348789_LUAD_TCGA-78-7155-01.png
exon_skip_354315_LUAD_TCGA-78-7155-01.png
exon_skip_38477_LUAD_TCGA-78-7155-01.png
exon_skip_7325_LUAD_TCGA-78-7155-01.png
	Sample: TCGA-B5-A0JY-01
	Cancer type: UCEC
	ESID: exon_skip_354315
	Skipped exon start: 1426311
	Skipped exon end: 1426794
	Mutation start: 1426309
	Mutation end: 1426309
	Mutation type: Splice_Site
	Reference seq: A
	Mutation seq: G
	AAchange: e8+2
	Sample: TCGA-B5-A0JY-01
	Cancer type: UCEC
	ESID: exon_skip_354314
	Skipped exon start: 1426311
	Skipped exon end: 1426475
	Mutation start: 1426309
	Mutation end: 1426309
	Mutation type: Splice_Site
	Reference seq: A
	Mutation seq: G
	AAchange: e8+2
exon_skip_2333_UCEC_TCGA-B5-A0JY-01.png
exon_skip_354315_UCEC_TCGA-B5-A0JY-01.png
exon_skip_382353_UCEC_TCGA-B5-A0JY-01.png
exon_skip_467199_UCEC_TCGA-B5-A0JY-01.png
exon_skip_506729_UCEC_TCGA-B5-A0JY-01.png
exon_skip_517484_UCEC_TCGA-B5-A0JY-01.png
exon_skip_517493_UCEC_TCGA-B5-A0JY-01.png
exon_skip_57854_UCEC_TCGA-B5-A0JY-01.png
exon_skip_64094_UCEC_TCGA-B5-A0JY-01.png
	Sample: TCGA-CD-A487-01
	Cancer type: STAD
	ESID: exon_skip_354315
	Skipped exon start: 1426311
	Skipped exon end: 1426794
	Mutation start: 1426464
	Mutation end: 1426465
	Mutation type: Frame_Shift_Ins
	Reference seq: -
	Mutation seq: G
	AAchange: p.Q266fs
	Sample: TCGA-CD-A487-01
	Cancer type: STAD
	ESID: exon_skip_354314
	Skipped exon start: 1426311
	Skipped exon end: 1426475
	Mutation start: 1426464
	Mutation end: 1426465
	Mutation type: Frame_Shift_Ins
	Reference seq: -
	Mutation seq: G
	AAchange: p.Q266fs
	Sample: TCGA-CD-A487-01
	Cancer type: STAD
	ESID: exon_skip_354315
	Skipped exon start: 1426311
	Skipped exon end: 1426794
	Mutation start: 1426465
	Mutation end: 1426466
	Mutation type: Frame_Shift_Ins
	Reference seq: -
	Mutation seq: G
	AAchange: p.Q266fs
	Sample: TCGA-CD-A487-01
	Cancer type: STAD
	ESID: exon_skip_354314
	Skipped exon start: 1426311
	Skipped exon end: 1426475
	Mutation start: 1426465
	Mutation end: 1426466
	Mutation type: Frame_Shift_Ins
	Reference seq: -
	Mutation seq: G
	AAchange: p.Q266fs
exon_skip_354315_STAD_TCGA-CD-A487-01.png
exon_skip_482547_STAD_TCGA-CD-A487-01.png

- Non-synonymous mutations located in the skipped exons in CCLE.

Sample	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
ACCMESO1_PLEURA	1426311	1426794	1426403	1426403	Frame_Shift_Del	G	-	p.S286fs
ACCMESO1_PLEURA	1426311	1426475	1426403	1426403	Frame_Shift_Del	G	-	p.S286fs
LS180_LARGE_INTESTINE	1426311	1426794	1426465	1426465	Frame_Shift_Del	G	-	p.Q266fs
LS180_LARGE_INTESTINE	1426311	1426475	1426465	1426465	Frame_Shift_Del	G	-	p.Q266fs
COLO205_LARGE_INTESTINE	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
COLO205_LARGE_INTESTINE	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
DMS53_LUNG	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
DMS53_LUNG	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
HCT116_LARGE_INTESTINE	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
HCT116_LARGE_INTESTINE	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
HCT15_LARGE_INTESTINE	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
HCT15_LARGE_INTESTINE	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
LS1034_LARGE_INTESTINE	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
LS1034_LARGE_INTESTINE	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
LS123_LARGE_INTESTINE	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
LS123_LARGE_INTESTINE	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
LS513_LARGE_INTESTINE	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
LS513_LARGE_INTESTINE	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
NAMALWA_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
NAMALWA_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
NCIH1694_LUNG	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
NCIH1694_LUNG	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
NCIH2052_PLEURA	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
NCIH2052_PLEURA	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
SNUC2B_LARGE_INTESTINE	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
SNUC2B_LARGE_INTESTINE	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
SW1463_LARGE_INTESTINE	1426311	1426794	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
SW1463_LARGE_INTESTINE	1426311	1426475	1426318	1426319	Frame_Shift_Ins	-	G	p.S315fs
LNCAPCLONEFGC_PROSTATE	1426311	1426794	1426317	1426317	Missense_Mutation	C	A	p.S315I
LNCAPCLONEFGC_PROSTATE	1426311	1426475	1426317	1426317	Missense_Mutation	C	A	p.S315I
SW1271_LUNG	1426311	1426794	1426348	1426348	Missense_Mutation	C	G	p.G305R
SW1271_LUNG	1426311	1426475	1426348	1426348	Missense_Mutation	C	G	p.G305R
HCC2998_LARGE_INTESTINE	1426311	1426794	1426362	1426362	Missense_Mutation	A	C	p.I300S
HCC2998_LARGE_INTESTINE	1426311	1426475	1426362	1426362	Missense_Mutation	A	C	p.I300S
HCT15_LARGE_INTESTINE	1426311	1426794	1426377	1426377	Missense_Mutation	G	A	p.T295I
HCT15_LARGE_INTESTINE	1426311	1426475	1426377	1426377	Missense_Mutation	G	A	p.T295I
GP5D_LARGE_INTESTINE	1426311	1426794	1426378	1426378	Missense_Mutation	T	C	p.T295A
GP5D_LARGE_INTESTINE	1426311	1426475	1426378	1426378	Missense_Mutation	T	C	p.T295A
SKNDZ_AUTONOMIC_GANGLIA	1426311	1426794	1426449	1426449	Missense_Mutation	C	A	p.S271I
SKNDZ_AUTONOMIC_GANGLIA	1426311	1426475	1426449	1426449	Missense_Mutation	C	A	p.S271I
HS766T_PANCREAS	1426311	1426794	1426457	1426457	Missense_Mutation	C	G	p.L268F
HS766T_PANCREAS	1426311	1426475	1426457	1426457	Missense_Mutation	C	G	p.L268F
COLO205_LARGE_INTESTINE	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
COLO320_LARGE_INTESTINE	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
COLO678_LARGE_INTESTINE	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
COLO679_SKIN	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
DMS53_LUNG	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
HUH7_LIVER	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
LS1034_LARGE_INTESTINE	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
LS123_LARGE_INTESTINE	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
NCIH2052_PLEURA	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
NCIH2228_LUNG	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
NCIH378_LUNG	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
SW1463_LARGE_INTESTINE	1434858	1434950	1434869	1434869	Missense_Mutation	A	G	p.S176P
BCP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	1434858	1434950	1434905	1434905	Missense_Mutation	C	G	p.E164Q

Top

Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for NSFL1C

sQTL information located at the skipped exons.

Exon skip ID	Chromosome	Three exons	Skippped exon	ENST	Cancer type	SNP id	Location	DNA change (ref/var)	P-value
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	GBM	rs41308086	chr20:1436445	T/A	5.31e-06
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	CESC	rs41308086	chr20:1436445	T/A	5.59e-04
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	COAD	rs41308086	chr20:1436445	T/A	8.62e-14
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	BLCA	rs41308086	chr20:1436445	T/A	1.31e-12
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	BLCA	rs41308086	chr20:1436445	T/A	2.23e-03
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	ESCA	rs41308086	chr20:1436445	T/A	7.09e-07
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	HNSC	rs41308086	chr20:1436445	T/A	5.57e-12
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	HNSC	rs41308086	chr20:1436445	T/A	6.41e-08
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	BRCA	rs41308086	chr20:1436445	T/A	2.39e-31
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	BRCA	rs41308086	chr20:1436445	T/A	1.49e-10
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	KIRP	rs41308086	chr20:1436445	T/A	1.26e-08
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	LGG	rs41308086	chr20:1436445	T/A	2.16e-23
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	LGG	rs41308086	chr20:1436445	T/A	7.04e-09
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	LGG	rs41308086	chr20:1436445	T/A	2.06e-03
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	KIRC	rs41308086	chr20:1436445	T/A	1.58e-12
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	KIRC	rs41308086	chr20:1436445	T/A	4.14e-12
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	KIRC	rs41308086	chr20:1436445	T/A	5.99e-08
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	LUAD	rs41308086	chr20:1436445	T/A	7.68e-14
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	LUAD	rs41308086	chr20:1436445	T/A	1.44e-03
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	LUSC	rs41308086	chr20:1436445	T/A	7.10e-18
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	LUSC	rs41308086	chr20:1436445	T/A	1.36e-03
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	LUSC	rs41308086	chr20:1436445	T/A	2.62e-03
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	OV	rs41308086	chr20:1436445	T/A	4.04e-10
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	PCPG	rs41308086	chr20:1436445	T/A	7.24e-04
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	PAAD	rs41308086	chr20:1436445	T/A	5.51e-09
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	PAAD	rs41308086	chr20:1436445	T/A	4.12e-05
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	PRAD	rs41308086	chr20:1436445	T/A	8.62e-12
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	PRAD	rs41308086	chr20:1436445	T/A	1.58e-04
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	SARC	rs41308086	chr20:1436445	T/A	4.76e-07
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	THYM	rs41308086	chr20:1436445	T/A	5.09e-04
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	TGCT	rs41308086	chr20:1436445	T/A	3.73e-11
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	STAD	rs41308086	chr20:1436445	T/A	1.53e-06
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	STAD	rs41308086	chr20:1436445	T/A	6.44e-04
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	THCA	rs41308086	chr20:1436445	T/A	4.73e-14
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	THCA	rs41308086	chr20:1436445	T/A	1.86e-05
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	UCEC	rs41308086	chr20:1436445	T/A	1.62e-10
exon_skip_354329	20	1435611:1435777:1436358:1436515:1438844:1438919	1436358:1436515	ENST00000489203.2	UCEC	rs41308086	chr20:1436445	T/A	1.70e-05
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	GBM	rs2064645	chr20:1426685	C/T	2.89e-06
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	CESC	rs2064645	chr20:1426685	C/T	4.97e-04
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	COAD	rs2064645	chr20:1426685	C/T	1.66e-12
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	BLCA	rs2064645	chr20:1426685	C/T	1.05e-12
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	ESCA	rs2064645	chr20:1426685	C/T	1.60e-06
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	HNSC	rs2064645	chr20:1426685	C/T	2.32e-11
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	HNSC	rs2064645	chr20:1426685	C/T	2.99e-07
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	BRCA	rs2064645	chr20:1426685	C/T	1.94e-33
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	BRCA	rs2064645	chr20:1426685	C/T	7.67e-11
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	BRCA	rs9575	chr20:1426393	C/T	1.65e-09
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	KIRP	rs2064645	chr20:1426685	C/T	1.41e-08
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	KIRP	rs9575	chr20:1426393	C/T	5.32e-04
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	LGG	rs2064645	chr20:1426685	C/T	2.78e-23
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	LGG	rs2064645	chr20:1426685	C/T	1.53e-08
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	LGG	rs9575	chr20:1426393	C/T	2.98e-06
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	LGG	rs2064645	chr20:1426685	C/T	2.12e-03
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	KIRC	rs2064645	chr20:1426685	C/T	8.88e-13
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	KIRC	rs2064645	chr20:1426685	C/T	6.27e-12
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	KIRC	rs2064645	chr20:1426685	C/T	4.22e-08
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	KIRC	rs9575	chr20:1426393	C/T	2.92e-03
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	LUAD	rs2064645	chr20:1426685	C/T	4.29e-14
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	LUAD	rs9575	chr20:1426393	C/T	4.61e-05
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	LUAD	rs2064645	chr20:1426685	C/T	1.21e-03
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	MESO	rs2064645	chr20:1426685	C/T	1.90e-04
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	MESO	rs2064645	chr20:1426685	C/T	2.34e-04
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	LIHC	rs2064645	chr20:1426685	C/T	9.04e-04
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	LUSC	rs2064645	chr20:1426685	C/T	2.00e-17
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	LUSC	rs2064645	chr20:1426685	C/T	4.32e-04
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	LUSC	rs2064645	chr20:1426685	C/T	8.88e-04
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	OV	rs2064645	chr20:1426685	C/T	5.05e-10
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	PAAD	rs2064645	chr20:1426685	C/T	3.04e-09
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	PAAD	rs2064645	chr20:1426685	C/T	3.31e-05
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	PRAD	rs2064645	chr20:1426685	C/T	6.89e-12
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	PRAD	rs2064645	chr20:1426685	C/T	1.01e-04
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	SARC	rs2064645	chr20:1426685	C/T	2.42e-08
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	SARC	rs2064645	chr20:1426685	C/T	9.88e-04
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	SARC	rs2064645	chr20:1426685	C/T	1.03e-03
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	THYM	rs2064645	chr20:1426685	C/T	5.09e-04
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	TGCT	rs2064645	chr20:1426685	C/T	2.45e-11
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	STAD	rs2064645	chr20:1426685	C/T	1.18e-06
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	THCA	rs2064645	chr20:1426685	C/T	4.73e-14
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	THCA	rs2064645	chr20:1426685	C/T	1.86e-05
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	THCA	rs9575	chr20:1426393	C/T	1.84e-03
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	UCEC	rs2064645	chr20:1426685	C/T	3.41e-11
exon_skip_354315	20	1424379:1424556:1426310:1426794:1433137:1433275	1426310:1426794	ENST00000381653.5	UCEC	rs2064645	chr20:1426685	C/T	6.41e-05
exon_skip_354314	20	1424379:1424556:1426310:1426475:1433137:1433275	1426310:1426475	ENST00000350991.4,ENST00000461211.1,ENST00000381658.4,ENST00000216879.4,ENST00000476071.1,ENST00000353088.2,ENST00000555944.1	BRCA	rs9575	chr20:1426393	C/T	1.65e-09
exon_skip_354314	20	1424379:1424556:1426310:1426475:1433137:1433275	1426310:1426475	ENST00000350991.4,ENST00000461211.1,ENST00000381658.4,ENST00000216879.4,ENST00000476071.1,ENST00000353088.2,ENST00000555944.1	KIRP	rs9575	chr20:1426393	C/T	5.32e-04
exon_skip_354314	20	1424379:1424556:1426310:1426475:1433137:1433275	1426310:1426475	ENST00000350991.4,ENST00000461211.1,ENST00000381658.4,ENST00000216879.4,ENST00000476071.1,ENST00000353088.2,ENST00000555944.1	LGG	rs9575	chr20:1426393	C/T	2.98e-06
exon_skip_354314	20	1424379:1424556:1426310:1426475:1433137:1433275	1426310:1426475	ENST00000350991.4,ENST00000461211.1,ENST00000381658.4,ENST00000216879.4,ENST00000476071.1,ENST00000353088.2,ENST00000555944.1	KIRC	rs9575	chr20:1426393	C/T	2.92e-03
exon_skip_354314	20	1424379:1424556:1426310:1426475:1433137:1433275	1426310:1426475	ENST00000350991.4,ENST00000461211.1,ENST00000381658.4,ENST00000216879.4,ENST00000476071.1,ENST00000353088.2,ENST00000555944.1	LUAD	rs9575	chr20:1426393	C/T	4.61e-05
exon_skip_354314	20	1424379:1424556:1426310:1426475:1433137:1433275	1426310:1426475	ENST00000350991.4,ENST00000461211.1,ENST00000381658.4,ENST00000216879.4,ENST00000476071.1,ENST00000353088.2,ENST00000555944.1	THCA	rs9575	chr20:1426393	C/T	1.84e-03

Top

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for NSFL1C

Top

Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for NSFL1C

Top

RelatedDrugs for NSFL1C

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for NSFL1C

Diseases associated with this gene.
(DisGeNet 4.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	Gene structures and expression levels
	Exon skipping events with PSIs in TCGA
	Exon skipping events with PSIs in GTEx
	Open reading frame (ORF) annotation in the exon skipping event
	Exon skipping events in the canonical protein sequence
	SNVs in the skipped exons with depth of coverage
	Splicing Quantitative Trait Loci (sQTLs) in the skipped exons
	Splicing Quantitative Trait Methylation (sQTM) in the skipped exon
	Related drugs with this gene
	Related diseases with this gene

Home

Download

Statistics

Landscape

Help

Contact

Gene summary for NSFL1C

Exon skipping events across known transcript of Ensembl for NSFL1C from UCSC genome browser

Gene isoform structures and expression levels for NSFL1C

Exon skipping events with PSIs in TCGA for NSFL1C

Exon skipping events with PSIs in GTEx for NSFL1C

Open reading frame (ORF) annotation in the exon skipping event for NSFL1C

Infer the effects of exon skipping event on protein functional features for NSFL1C

SNVs in the skipped exons for NSFL1C

Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for NSFL1C

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for NSFL1C

Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for NSFL1C

RelatedDrugs for NSFL1C

RelatedDiseases for NSFL1C