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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in TCGA

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Exon skipping events with PSIs in GTEx

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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SNVs in the skipped exons with depth of coverage

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

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Related drugs with this gene

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Related diseases with this gene

Gene summary for ARHGEF40

check button Gene summary
Gene informationGene symbol

ARHGEF40

Gene ID

55701

Gene nameRho guanine nucleotide exchange factor 40
SynonymsSOLO
Cytomap

14q11.2

Type of geneprotein-coding
Descriptionrho guanine nucleotide exchange factor 40Rho guanine nucleotide exchange factor (GEF) 40protein SOLO
Modification date20180519
UniProtAcc

Q8TER5

ContextPubMed: ARHGEF40 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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Exon skipping events across known transcript of Ensembl for ARHGEF40 from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Gene isoform structures and expression levels for ARHGEF40

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


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Exon skipping events with PSIs in TCGA for ARHGEF40

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_1050391421538526:21538558:21541203:21541401:21542090:2154315021541203:21541401ENSG00000165801.5ENST00000556399.1,ENST00000298693.3,ENST00000555038.1,ENST00000553709.1
exon_skip_1050461421541203:21541401:21542090:21543150:21543490:2154365821542090:21543150ENSG00000165801.5ENST00000556399.1
exon_skip_1050471421541203:21541401:21542090:21543339:21543490:2154365821542090:21543339ENSG00000165801.5ENST00000298693.3,ENST00000555038.1,ENST00000298694.4,ENST00000553709.1
exon_skip_1050521421543490:21543658:21543781:21543924:21544518:2154461521543781:21543924ENSG00000165801.5ENST00000556399.1
exon_skip_1050541421543490:21543658:21543803:21543924:21544518:2154461521543803:21543924ENSG00000165801.5ENST00000298693.3,ENST00000298694.4,ENST00000553709.1
exon_skip_1050561421544721:21544802:21544932:21545049:21546335:2154636621544932:21545049ENSG00000165801.5ENST00000556399.1,ENST00000298693.3,ENST00000298694.4,ENST00000555232.1,ENST00000553709.1
exon_skip_1050581421546335:21546431:21546531:21546647:21547042:2154716921546531:21546647ENSG00000165801.5ENST00000556399.1,ENST00000298693.3,ENST00000298694.4,ENST00000553709.1
exon_skip_1050621421548818:21548941:21549031:21549175:21549667:2155027821549031:21549175ENSG00000165801.5ENST00000556399.1,ENST00000298693.3,ENST00000298694.4,ENST00000553709.1
exon_skip_1050651421550989:21551076:21551993:21552209:21552911:2155308221551993:21552209ENSG00000165801.5ENST00000554514.1,ENST00000556399.1,ENST00000298693.3,ENST00000298694.4,ENST00000555232.1,ENST00000553709.1
exon_skip_1050671421553847:21554025:21555159:21555264:21555478:2155562221555159:21555264ENSG00000165801.5ENST00000298694.4,ENST00000553709.1
exon_skip_1050691421553847:21554025:21555159:21555264:21556126:2155625721555159:21555264ENSG00000165801.5ENST00000556399.1,ENST00000298693.3
exon_skip_1050741421553847:21554025:21555159:21555622:21556126:2155625721555159:21555622ENSG00000165801.5ENST00000554514.1
exon_skip_1050781421555159:21555264:21555478:21555622:21556126:2155625721555478:21555622ENSG00000165801.5ENST00000298694.4,ENST00000553709.1

check button PSI values of skipped exons in TCGA.
psi tcga

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Exon skipping events with PSIs in GTEx for ARHGEF40

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_1050391421538526:21538558:21541203:21541401:21542090:2154315021541203:21541401ENSG00000165801.5ENST00000555038.1,ENST00000556399.1,ENST00000553709.1,ENST00000298693.3
exon_skip_1050461421541203:21541401:21542090:21543150:21543490:2154365821542090:21543150ENSG00000165801.5ENST00000556399.1
exon_skip_1050471421541203:21541401:21542090:21543339:21543490:2154365821542090:21543339ENSG00000165801.5ENST00000298694.4,ENST00000555038.1,ENST00000553709.1,ENST00000298693.3
exon_skip_1050521421543490:21543658:21543781:21543924:21544518:2154461521543781:21543924ENSG00000165801.5ENST00000556399.1
exon_skip_1050541421543490:21543658:21543803:21543924:21544518:2154461521543803:21543924ENSG00000165801.5ENST00000298694.4,ENST00000553709.1,ENST00000298693.3
exon_skip_1050561421544721:21544802:21544932:21545049:21546335:2154636621544932:21545049ENSG00000165801.5ENST00000298694.4,ENST00000556399.1,ENST00000553709.1,ENST00000555232.1,ENST00000298693.3
exon_skip_1050581421546335:21546431:21546531:21546647:21547042:2154716921546531:21546647ENSG00000165801.5ENST00000298694.4,ENST00000556399.1,ENST00000553709.1,ENST00000298693.3
exon_skip_1050621421548818:21548941:21549031:21549175:21549667:2155027821549031:21549175ENSG00000165801.5ENST00000298694.4,ENST00000556399.1,ENST00000553709.1,ENST00000298693.3
exon_skip_1050651421550989:21551076:21551993:21552209:21552911:2155308221551993:21552209ENSG00000165801.5ENST00000298694.4,ENST00000556399.1,ENST00000553709.1,ENST00000555232.1,ENST00000298693.3,ENST00000554514.1
exon_skip_1050671421553847:21554025:21555159:21555264:21555478:2155562221555159:21555264ENSG00000165801.5ENST00000298694.4,ENST00000553709.1
exon_skip_1050691421553847:21554025:21555159:21555264:21556126:2155625721555159:21555264ENSG00000165801.5ENST00000556399.1,ENST00000298693.3
exon_skip_1050741421553847:21554025:21555159:21555622:21556126:2155625721555159:21555622ENSG00000165801.5ENST00000554514.1
exon_skip_1050781421555159:21555264:21555478:21555622:21556126:2155625721555478:21555622ENSG00000165801.5ENST00000298694.4,ENST00000553709.1

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for ARHGEF40

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000002986942154209021543339Frame-shift
ENST000002986942154380321543924Frame-shift
ENST000002986942154653121546647Frame-shift
ENST000002986942154493221545049In-frame
ENST000002986942154903121549175In-frame
ENST000002986942155199321552209In-frame
ENST000002986942155515921555264In-frame
ENST000002986942155547821555622In-frame

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000002986942154209021543339Frame-shift
ENST000002986942154380321543924Frame-shift
ENST000002986942154653121546647Frame-shift
ENST000002986942154493221545049In-frame
ENST000002986942154903121549175In-frame
ENST000002986942155199321552209In-frame
ENST000002986942155515921555264In-frame
ENST000002986942155547821555622In-frame

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Infer the effects of exon skipping event on protein functional features for ARHGEF40

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000029869459361519215449322154504920452161639678
ENST0000029869459361519215490312154917526242767832880
ENST000002986945936151921551993215522093701391611911263
ENST000002986945936151921555159215552644266437013791414
ENST000002986945936151921555478215556224371451414141462

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000029869459361519215449322154504920452161639678
ENST0000029869459361519215490312154917526242767832880
ENST000002986945936151921551993215522093701391611911263
ENST000002986945936151921555159215552644266437013791414
ENST000002986945936151921555478215556224371451414141462

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q8TER56396781714Alternative sequenceID=VSP_030381;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q8TER563967811519ChainID=PRO_0000314822;Note=Rho guanine nucleotide exchange factor 40
Q8TER583288011519ChainID=PRO_0000314822;Note=Rho guanine nucleotide exchange factor 40
Q8TER5832880828871Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q8TER51191126311519ChainID=PRO_0000314822;Note=Rho guanine nucleotide exchange factor 40
Q8TER51191126310851253DomainNote=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Q8TER51379141411519ChainID=PRO_0000314822;Note=Rho guanine nucleotide exchange factor 40
Q8TER51414146214151519Alternative sequenceID=VSP_030382;Note=In isoform 3. AARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQISLAPETLDSSGDVSPGPRNSPSLQPPHPGSSTPTLASRGILGLSRQSHARALSDPTTPL->GEGQGAGGWPPGVKTLTMRIQRGGMVESQERHLVPKSVGLAGRPSVRLRVIPGSQEGFPTPAPHPPLPTLCSRPHPGLRGRVIL;Ontology_term=ECO:0000303;evid
Q8TER51414146214151462Alternative sequenceID=VSP_030383;Note=In isoform 4. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
Q8TER51414146211519ChainID=PRO_0000314822;Note=Rho guanine nucleotide exchange factor 40
Q8TER51414146214331433Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:24275569;Dbxref=PMID:24275569
Q8TER51414146214381438Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:24275569;Dbxref=PMID:24275569
Q8TER51414146214181418Natural variantID=VAR_060541;Note=T->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15489334;Dbxref=dbSNP:rs17855344,PMID:15489334


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q8TER56396781714Alternative sequenceID=VSP_030381;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
Q8TER563967811519ChainID=PRO_0000314822;Note=Rho guanine nucleotide exchange factor 40
Q8TER583288011519ChainID=PRO_0000314822;Note=Rho guanine nucleotide exchange factor 40
Q8TER5832880828871Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q8TER51191126311519ChainID=PRO_0000314822;Note=Rho guanine nucleotide exchange factor 40
Q8TER51191126310851253DomainNote=DH;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00062
Q8TER51379141411519ChainID=PRO_0000314822;Note=Rho guanine nucleotide exchange factor 40
Q8TER51414146214151519Alternative sequenceID=VSP_030382;Note=In isoform 3. AARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQISLAPETLDSSGDVSPGPRNSPSLQPPHPGSSTPTLASRGILGLSRQSHARALSDPTTPL->GEGQGAGGWPPGVKTLTMRIQRGGMVESQERHLVPKSVGLAGRPSVRLRVIPGSQEGFPTPAPHPPLPTLCSRPHPGLRGRVIL;Ontology_term=ECO:0000303;evid
Q8TER51414146214151462Alternative sequenceID=VSP_030383;Note=In isoform 4. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
Q8TER51414146211519ChainID=PRO_0000314822;Note=Rho guanine nucleotide exchange factor 40
Q8TER51414146214331433Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:24275569;Dbxref=PMID:24275569
Q8TER51414146214381438Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:24275569;Dbxref=PMID:24275569
Q8TER51414146214181418Natural variantID=VAR_060541;Note=T->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15489334;Dbxref=dbSNP:rs17855344,PMID:15489334


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SNVs in the skipped exons for ARHGEF40

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
LIHCTCGA-DD-A1EG-01exon_skip_105039
21541204215414012154127421541274Frame_Shift_DelC-p.A25fs
HNSCTCGA-F7-A624-01exon_skip_105058
21546532215466472154660421546604Frame_Shift_DelG-p.G736fs
LIHCTCGA-G3-A3CJ-01exon_skip_105058
21546532215466472154660421546604Frame_Shift_DelG-p.G736fs
STADTCGA-VQ-A8P2-01exon_skip_105058
21546532215466472154660421546604Frame_Shift_DelG-p.D734fs
STADTCGA-VQ-A8P2-01exon_skip_105058
21546532215466472154660421546604Frame_Shift_DelG-p.G736fs
LIHCTCGA-G3-A3CJ-01exon_skip_105065
21551994215522092155202821552028Frame_Shift_DelC-p.A1203fs
KIRCTCGA-A3-3316-01exon_skip_105058
21546532215466472154660321546604Frame_Shift_Ins-Gp.EG734fs
KIRCTCGA-A3-3320-01exon_skip_105058
21546532215466472154660321546604Frame_Shift_Ins-Gp.EG734fs
KIRCTCGA-A3-3363-01exon_skip_105058
21546532215466472154660321546604Frame_Shift_Ins-Gp.EG734fs
KIRCTCGA-A3-3374-01exon_skip_105058
21546532215466472154660321546604Frame_Shift_Ins-Gp.EG734fs
KIRCTCGA-A3-3383-01exon_skip_105058
21546532215466472154660321546604Frame_Shift_Ins-Gp.EG734fs
KIRCTCGA-AK-3465-01exon_skip_105058
21546532215466472154660321546604Frame_Shift_Ins-Gp.EG734fs
LUADTCGA-64-1678-01exon_skip_105058
21546532215466472154660321546604Frame_Shift_Ins-Gp.EG734fs
LUADTCGA-67-3770-01exon_skip_105058
21546532215466472154660321546604Frame_Shift_Ins-Gp.EG734fs
UCECTCGA-AP-A059-01exon_skip_105046
21542091215431502154242321542423Nonsense_MutationGAp.W178*
UCECTCGA-AP-A059-01exon_skip_105047
21542091215433392154242321542423Nonsense_MutationGAp.W178*
PRADTCGA-XK-AAIW-01exon_skip_105046
21542091215431502154303921543039Nonsense_MutationCTp.R384*
PRADTCGA-XK-AAIW-01exon_skip_105047
21542091215433392154303921543039Nonsense_MutationCTp.R384*
ACCTCGA-P6-A5OG-01exon_skip_105065
21551994215522092155214121552141Nonsense_MutationCTp.Q1241*
ACCTCGA-P6-A5OG-01exon_skip_105065
21551994215522092155214121552141Nonsense_MutationCTp.Q1241X

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21542091215433392154289521542895Frame_Shift_DelC-p.P337fs
JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21542091215431502154289521542895Frame_Shift_DelC-p.P337fs
MN60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21542091215433392154297821542978Frame_Shift_DelG-p.Q363fs
MN60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21542091215431502154297821542978Frame_Shift_DelG-p.Q363fs
RKO_LARGE_INTESTINE21546532215466472154660421546604Frame_Shift_DelG-p.G736fs
MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21546532215466472154660421546604Frame_Shift_DelG-p.G736fs
REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21546532215466472154660421546604Frame_Shift_DelG-p.G736fs
RERFLCKJ_LUNG21555160215556222155558021555582In_Frame_DelGAG-p.E1451del
RERFLCKJ_LUNG21555479215556222155558021555582In_Frame_DelGAG-p.E1451del
YH13_CENTRAL_NERVOUS_SYSTEM21541204215414012154124321541243Missense_MutationGAp.A15T
LNCAPCLONEFGC_PROSTATE21541204215414012154132821541328Missense_MutationAGp.D43G
SNU407_LARGE_INTESTINE21541204215414012154134521541345Missense_MutationCAp.L49M
LOXIMVI_SKIN21542091215433392154210421542104Missense_MutationGCp.G72A
LOXIMVI_SKIN21542091215431502154210421542104Missense_MutationGCp.G72A
RMUGS_OVARY21542091215433392154215421542154Missense_MutationGCp.V89L
RMUGS_OVARY21542091215431502154215421542154Missense_MutationGCp.V89L
FU97_STOMACH21542091215433392154228021542280Missense_MutationGAp.V131M
FU97_STOMACH21542091215431502154228021542280Missense_MutationGAp.V131M
NCIH1975_LUNG21542091215433392154230821542308Missense_MutationCTp.A140V
NCIH1975_LUNG21542091215431502154230821542308Missense_MutationCTp.A140V
LNCAPCLONEFGC_PROSTATE21542091215433392154231421542314Missense_MutationCTp.A142V
LNCAPCLONEFGC_PROSTATE21542091215431502154231421542314Missense_MutationCTp.A142V
HEC151_ENDOMETRIUM21542091215433392154245621542456Missense_MutationACp.K189N
HEC151_ENDOMETRIUM21542091215431502154245621542456Missense_MutationACp.K189N
HARA_LUNG21542091215433392154249721542497Missense_MutationCGp.P203R
HARA_LUNG21542091215431502154249721542497Missense_MutationCGp.P203R
SNU1040_LARGE_INTESTINE21542091215433392154263221542632Missense_MutationTCp.V248A
SNU1040_LARGE_INTESTINE21542091215431502154263221542632Missense_MutationTCp.V248A
HCC2450_LUNG21542091215433392154265421542654Missense_MutationCAp.S255R
HCC2450_LUNG21542091215431502154265421542654Missense_MutationCAp.S255R
KYSE270_OESOPHAGUS21542091215433392154269521542695Missense_MutationGCp.R269P
KYSE270_OESOPHAGUS21542091215431502154269521542695Missense_MutationGCp.R269P
RO82W1_THYROID21542091215433392154283521542835Missense_MutationCTp.P316S
RO82W1_THYROID21542091215431502154283521542835Missense_MutationCTp.P316S
RPMI8866_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21542091215433392154329821543298Missense_MutationGCp.G470A
NCIH2196_LUNG21542091215433392154332121543321Missense_MutationGAp.G478S
639V_URINARY_TRACT21542091215433392154333621543336Missense_MutationGAp.A483T
SUDHL6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21543782215439242154381621543816Missense_MutationATp.Q544L
SUDHL6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21543804215439242154381621543816Missense_MutationATp.Q544L
AN3CA_ENDOMETRIUM21543782215439242154384921543849Missense_MutationCTp.P555L
AN3CA_ENDOMETRIUM21543804215439242154384921543849Missense_MutationCTp.P555L
MCC13_SKIN21543782215439242154390221543902Missense_MutationCTp.H573Y
MCC13_SKIN21543804215439242154390221543902Missense_MutationCTp.H573Y
BICR18_UPPER_AERODIGESTIVE_TRACT21544933215450492154494221544942Missense_MutationGTp.V643L
DOV13_OVARY21544933215450492154495521544955Missense_MutationAGp.N647S
BICR18_UPPER_AERODIGESTIVE_TRACT21544933215450492154495621544956Missense_MutationTGp.N647K
SNU81_LARGE_INTESTINE21544933215450492154495721544957Missense_MutationGTp.D648Y
HCT15_LARGE_INTESTINE21546532215466472154659221546592Missense_MutationCGp.L731V
EN_ENDOMETRIUM21546532215466472154661121546611Missense_MutationCGp.A737G
MHHPREB1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21549032215491752154905521549055Missense_MutationGTp.E840D
SKMES1_LUNG21549032215491752154914421549144Missense_MutationGTp.R870L
PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21549032215491752154916221549162Missense_MutationGAp.R876H
TGBC11TKB_STOMACH21551994215522092155206621552066Missense_MutationCTp.R1216W
L82_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21551994215522092155212121552121Missense_MutationGAp.R1234Q
HCC1438_LUNG21551994215522092155212121552121Missense_MutationGTp.R1234L
HS746T_STOMACH21551994215522092155216521552165Missense_MutationCTp.R1249C
FTC133_THYROID21551994215522092155216921552169Missense_MutationGTp.G1250V
HCC2450_LUNG21551994215522092155217221552172Missense_MutationGCp.R1251T
TT2609C02_THYROID21551994215522092155219321552193Missense_MutationCTp.A1258V
FARAGE_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21555160215552642155520321555203Missense_MutationACp.K1394N
FARAGE_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21555160215556222155520321555203Missense_MutationACp.K1394N
PL18_PANCREAS21555160215552642155520421555204Missense_MutationCGp.P1395A
PL18_PANCREAS21555160215556222155520421555204Missense_MutationCGp.P1395A
JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21555160215552642155524721555247Missense_MutationCTp.A1409V
JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE21555160215556222155524721555247Missense_MutationCTp.A1409V
HEC1A_ENDOMETRIUM21542091215433392154328521543285Nonsense_MutationGTp.E466*
SNU349_KIDNEY21544933215450492154503421545034Nonsense_MutationGAp.W673*

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ARHGEF40

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ARHGEF40


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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ARHGEF40


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RelatedDrugs for ARHGEF40

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ARHGEF40

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource