ExonSkipDB Logo

Home

Download

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
leaf

Gene summary

leaf

Gene structures and expression levels

leaf

Exon skipping events with PSIs in TCGA

leaf

Exon skipping events with PSIs in GTEx

leaf

Open reading frame (ORF) annotation in the exon skipping event

leaf

Exon skipping events in the canonical protein sequence

leaf

SNVs in the skipped exons with depth of coverage

leaf

Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

leaf

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

leaf

Related drugs with this gene

leaf

Related diseases with this gene

Gene summary for PLXNB1

check button Gene summary
Gene informationGene symbol

PLXNB1

Gene ID

5364

Gene nameplexin B1
SynonymsPLEXIN-B1|PLXN5|SEP
Cytomap

3p21.31

Type of geneprotein-coding
Descriptionplexin-B1plexin 5semaphorin receptor SEP
Modification date20180523
UniProtAcc

O43157

ContextPubMed: PLXNB1 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
PLXNB1

GO:0007162

negative regulation of cell adhesion

15218527

PLXNB1

GO:0008360

regulation of cell shape

19843518

PLXNB1

GO:0051493

regulation of cytoskeleton organization

19843518

PLXNB1

GO:0071526

semaphorin-plexin signaling pathway

15218527|19843518


Top

Exon skipping events across known transcript of Ensembl for PLXNB1 from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

Top

Gene isoform structures and expression levels for PLXNB1

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


Top

Exon skipping events with PSIs in TCGA for PLXNB1

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_383448348445915:48445997:48447130:48447205:48448229:4844830548447130:48447205ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000448774.2,ENST00000456774.1,ENST00000358536.4
exon_skip_383457348447130:48447205:48448229:48448305:48448433:4844849848448229:48448305ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000448774.2,ENST00000456774.1,ENST00000358536.4
exon_skip_383461348448433:48448498:48450736:48450884:48450978:4845112748450736:48450884ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000448774.2,ENST00000483676.1,ENST00000456774.1,ENST00000358536.4
exon_skip_383464348450978:48451139:48451313:48451486:48451704:4845177448451313:48451486ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000448774.2,ENST00000456774.1,ENST00000478171.1,ENST00000358536.4
exon_skip_383470348451423:48451486:48451704:48451789:48451863:4845190248451704:48451789ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000470525.1,ENST00000485535.1,ENST00000448774.2,ENST00000456774.1,ENST00000358536.4
exon_skip_383477348451863:48451967:48452276:48452445:48453271:4845337648452276:48452445ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000448774.2,ENST00000456774.1,ENST00000358536.4
exon_skip_383480348453271:48453418:48453646:48453713:48453850:4845402948453646:48453713ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000448774.2,ENST00000456774.1,ENST00000358536.4
exon_skip_383496348454477:48454578:48455078:48455227:48455303:4845541548455078:48455227ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000448774.2,ENST00000456774.1,ENST00000358536.4
exon_skip_383505348456620:48456756:48456991:48457168:48457439:4845757648456991:48457168ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000464294.1,ENST00000449094.1,ENST00000456774.1,ENST00000358536.4
exon_skip_383507348457439:48457576:48457754:48457860:48459319:4845947148457754:48457860ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000449094.1,ENST00000456774.1,ENST00000358536.4
exon_skip_383510348459319:48459471:48459599:48459772:48459857:4845995148459599:48459772ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000449094.1,ENST00000456774.1,ENST00000358536.4
exon_skip_383513348459857:48459951:48460325:48460448:48460652:4846077548460325:48460448ENSG00000164050.8ENST00000462738.1,ENST00000296440.6,ENST00000358459.4,ENST00000449094.1,ENST00000456774.1,ENST00000358536.4
exon_skip_383515348460325:48460448:48460652:48460775:48460985:4846108348460652:48460775ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000449094.1,ENST00000456774.1,ENST00000358536.4
exon_skip_383517348460652:48460775:48460985:48461083:48462073:4846218248460985:48461083ENSG00000164050.8ENST00000449094.1
exon_skip_383519348460652:48460775:48460985:48461666:48462073:4846218248460985:48461666ENSG00000164050.8ENST00000296440.6,ENST00000358536.4
exon_skip_383529348461013:48461083:48461632:48461666:48462073:4846218248461632:48461666ENSG00000164050.8ENST00000358459.4,ENST00000456774.1
exon_skip_383534348462256:48462365:48462636:48462793:48463082:4846320948462636:48462793ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000449094.1,ENST00000456774.1,ENST00000358536.4
exon_skip_383538348463082:48463215:48463513:48463614:48463739:4846386848463513:48463614ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000449094.1,ENST00000456774.1,ENST00000358536.4
exon_skip_383545348463531:48463614:48463739:48463868:48464173:4846435648463739:48463868ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000449094.1,ENST00000456774.1,ENST00000358536.4
exon_skip_383549348463739:48463868:48464173:48464356:48464913:4846498348464173:48464356ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000449094.1,ENST00000456774.1,ENST00000358536.4
exon_skip_383553348464913:48466026:48466689:48466742:48470661:4847087248466689:48466742ENSG00000164050.8ENST00000358459.4,ENST00000358536.4

check button PSI values of skipped exons in TCGA.
psi tcga

Top

Exon skipping events with PSIs in GTEx for PLXNB1

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_383448348445915:48445997:48447130:48447205:48448229:4844830548447130:48447205ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000358536.4,ENST00000448774.2,ENST00000456774.1
exon_skip_383457348447130:48447205:48448229:48448305:48448433:4844849848448229:48448305ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000358536.4,ENST00000448774.2,ENST00000456774.1
exon_skip_383461348448433:48448498:48450736:48450884:48450978:4845112748450736:48450884ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000358536.4,ENST00000448774.2,ENST00000456774.1,ENST00000483676.1
exon_skip_383464348450978:48451139:48451313:48451486:48451704:4845177448451313:48451486ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000358536.4,ENST00000448774.2,ENST00000456774.1,ENST00000478171.1
exon_skip_383470348451423:48451486:48451704:48451789:48451863:4845190248451704:48451789ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000358536.4,ENST00000448774.2,ENST00000456774.1,ENST00000470525.1
exon_skip_383477348451863:48451967:48452276:48452445:48453271:4845337648452276:48452445ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000358536.4,ENST00000448774.2,ENST00000456774.1
exon_skip_383480348453271:48453418:48453646:48453713:48453850:4845402948453646:48453713ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000485535.1,ENST00000358536.4,ENST00000448774.2,ENST00000456774.1
exon_skip_383496348454477:48454578:48455078:48455227:48455303:4845541548455078:48455227ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000358536.4,ENST00000448774.2,ENST00000456774.1
exon_skip_383505348456620:48456756:48456991:48457168:48457439:4845757648456991:48457168ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000358536.4,ENST00000456774.1,ENST00000449094.1,ENST00000464294.1
exon_skip_383507348457439:48457576:48457754:48457860:48459319:4845947148457754:48457860ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000358536.4,ENST00000456774.1,ENST00000449094.1
exon_skip_383510348459319:48459471:48459599:48459772:48459857:4845995148459599:48459772ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000358536.4,ENST00000456774.1,ENST00000449094.1
exon_skip_383513348459857:48459951:48460325:48460448:48460652:4846077548460325:48460448ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000358536.4,ENST00000456774.1,ENST00000449094.1,ENST00000462738.1
exon_skip_383515348460325:48460448:48460652:48460775:48460985:4846108348460652:48460775ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000358536.4,ENST00000456774.1,ENST00000449094.1
exon_skip_383517348460652:48460775:48460985:48461083:48462073:4846218248460985:48461083ENSG00000164050.8ENST00000449094.1
exon_skip_383519348460652:48460775:48460985:48461666:48462073:4846218248460985:48461666ENSG00000164050.8ENST00000296440.6,ENST00000358536.4
exon_skip_383529348461013:48461083:48461632:48461666:48462073:4846218248461632:48461666ENSG00000164050.8ENST00000358459.4,ENST00000456774.1
exon_skip_383534348462256:48462365:48462636:48462793:48463082:4846320948462636:48462793ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000358536.4,ENST00000456774.1,ENST00000449094.1
exon_skip_383538348463082:48463215:48463513:48463614:48463739:4846386848463513:48463614ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000358536.4,ENST00000456774.1,ENST00000449094.1
exon_skip_383545348463531:48463614:48463739:48463868:48464173:4846435648463739:48463868ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000358536.4,ENST00000456774.1,ENST00000449094.1
exon_skip_383549348463739:48463868:48464173:48464356:48464913:4846498348464173:48464356ENSG00000164050.8ENST00000296440.6,ENST00000358459.4,ENST00000358536.4,ENST00000456774.1,ENST00000449094.1
exon_skip_383553348464913:48466026:48466689:48466742:48470661:4847087248466689:48466742ENSG00000164050.8ENST00000358459.4,ENST00000358536.4

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

Top

Open reading frame (ORF) annotation in the exon skipping event for PLXNB1

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000035853648466689484667423UTR-3UTR
ENST000002964404844822948448305Frame-shift
ENST000003585364844822948448305Frame-shift
ENST000002964404845073648450884Frame-shift
ENST000003585364845073648450884Frame-shift
ENST000002964404845131348451486Frame-shift
ENST000003585364845131348451486Frame-shift
ENST000002964404845170448451789Frame-shift
ENST000003585364845170448451789Frame-shift
ENST000002964404845227648452445Frame-shift
ENST000003585364845227648452445Frame-shift
ENST000002964404845364648453713Frame-shift
ENST000003585364845364648453713Frame-shift
ENST000002964404845507848455227Frame-shift
ENST000003585364845507848455227Frame-shift
ENST000002964404845775448457860Frame-shift
ENST000003585364845775448457860Frame-shift
ENST000002964404845959948459772Frame-shift
ENST000003585364845959948459772Frame-shift
ENST000002964404846263648462793Frame-shift
ENST000003585364846263648462793Frame-shift
ENST000002964404846351348463614Frame-shift
ENST000003585364846351348463614Frame-shift
ENST000002964404844713048447205In-frame
ENST000003585364844713048447205In-frame
ENST000002964404845699148457168In-frame
ENST000003585364845699148457168In-frame
ENST000002964404846032548460448In-frame
ENST000003585364846032548460448In-frame
ENST000002964404846065248460775In-frame
ENST000003585364846065248460775In-frame
ENST000002964404846098548461666In-frame
ENST000003585364846098548461666In-frame
ENST000002964404846373948463868In-frame
ENST000003585364846373948463868In-frame
ENST000002964404846417348464356In-frame
ENST000003585364846417348464356In-frame

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000035853648466689484667423UTR-3UTR
ENST000002964404844822948448305Frame-shift
ENST000003585364844822948448305Frame-shift
ENST000002964404845073648450884Frame-shift
ENST000003585364845073648450884Frame-shift
ENST000002964404845131348451486Frame-shift
ENST000003585364845131348451486Frame-shift
ENST000002964404845170448451789Frame-shift
ENST000003585364845170448451789Frame-shift
ENST000002964404845227648452445Frame-shift
ENST000003585364845227648452445Frame-shift
ENST000002964404845364648453713Frame-shift
ENST000003585364845364648453713Frame-shift
ENST000002964404845507848455227Frame-shift
ENST000003585364845507848455227Frame-shift
ENST000002964404845775448457860Frame-shift
ENST000003585364845775448457860Frame-shift
ENST000002964404845959948459772Frame-shift
ENST000003585364845959948459772Frame-shift
ENST000002964404846263648462793Frame-shift
ENST000003585364846263648462793Frame-shift
ENST000002964404846351348463614Frame-shift
ENST000003585364846351348463614Frame-shift
ENST000002964404844713048447205In-frame
ENST000003585364844713048447205In-frame
ENST000002964404845699148457168In-frame
ENST000003585364845699148457168In-frame
ENST000002964404846032548460448In-frame
ENST000003585364846032548460448In-frame
ENST000002964404846065248460775In-frame
ENST000003585364846065248460775In-frame
ENST000002964404846098548461666In-frame
ENST000003585364846098548461666In-frame
ENST000002964404846373948463868In-frame
ENST000003585364846373948463868In-frame
ENST000002964404846417348464356In-frame
ENST000003585364846417348464356In-frame

Top

Infer the effects of exon skipping event on protein functional features for PLXNB1

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000029644071602135484641734846435612111393369430
ENST0000035853673252135484641734846435613781560369430
ENST0000029644071602135484637394846386813941522430473
ENST0000035853673252135484637394846386815611689430473
ENST0000029644071602135484609854846166621322812676903
ENST0000035853673252135484609854846166622992979676903
ENST0000029644071602135484606524846077528132935903944
ENST0000035853673252135484606524846077529803102903944
ENST0000029644071602135484603254846044829363058944985
ENST0000035853673252135484603254846044831033225944985
ENST000002964407160213548456991484571683721389712061264
ENST000003585367325213548456991484571683888406412061264
ENST000002964407160213548447130484472056332640620762101
ENST000003585367325213548447130484472056499657320762101

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000029644071602135484641734846435612111393369430
ENST0000035853673252135484641734846435613781560369430
ENST0000029644071602135484637394846386813941522430473
ENST0000035853673252135484637394846386815611689430473
ENST0000029644071602135484609854846166621322812676903
ENST0000035853673252135484609854846166622992979676903
ENST0000029644071602135484606524846077528132935903944
ENST0000035853673252135484606524846077529803102903944
ENST0000029644071602135484603254846044829363058944985
ENST0000035853673252135484603254846044831033225944985
ENST000002964407160213548456991484571683721389712061264
ENST000003585367325213548456991484571683888406412061264
ENST000002964407160213548447130484472056332640620762101
ENST000003585367325213548447130484472056499657320762101

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
O43157369430380382Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430380382Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430385390Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430385390Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430392394Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430392394Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430397400Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430397400Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430405413Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430405413Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430416423Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430416423Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430426432Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430426432Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157369430202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157369430252377Disulfide bondOntology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O43157369430252377Disulfide bondOntology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O4315736943020479DomainNote=Sema;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O4315736943020479DomainNote=Sema;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O43157369430370374HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430370374HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430389389Natural variantID=VAR_050598;Note=R->W;Dbxref=dbSNP:rs34050056
O43157369430389389Natural variantID=VAR_050598;Note=R->W;Dbxref=dbSNP:rs34050056
O43157369430201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157369430201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157430473426432Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473426432Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473434436Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3OL2
O43157430473434436Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3OL2
O43157430473442448Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473442448Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473463469Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473463469Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157430473202135ChainID=PRO_0000024671;Note=Plexin-B1
O4315743047320479DomainNote=Sema;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O4315743047320479DomainNote=Sema;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O43157430473201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157430473201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157676903677729Alternative sequenceID=VSP_011513;Note=In isoform 3. SPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGAS->VMETQQSLRALPPPSSSRPASTTSMTPPGSGSWKRRPWGQAPAPVWRAFRAPR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157676903677729Alternative sequenceID=VSP_011513;Note=In isoform 3. SPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGAS->VMETQQSLRALPPPSSSRPASTTSMTPPGSGSWKRRPWGQAPAPVWRAFRAPR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157676903688870Alternative sequenceID=VSP_011514;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157676903688870Alternative sequenceID=VSP_011514;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O431576769037302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O431576769037302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157676903202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157676903202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157676903678829Compositional biasNote=Pro-rich
O43157676903678829Compositional biasNote=Pro-rich
O43157676903753753Natural variantID=VAR_050599;Note=S->L;Dbxref=dbSNP:rs35592743
O43157676903753753Natural variantID=VAR_050599;Note=S->L;Dbxref=dbSNP:rs35592743
O43157676903201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157676903201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O431579039447302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O431579039447302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157903944202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157903944202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157903944201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157903944201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O431579449857302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O431579449857302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157944985202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157944985202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157944985201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157944985201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157120612647302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157120612647302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O4315712061264202135ChainID=PRO_0000024671;Note=Plexin-B1
O4315712061264202135ChainID=PRO_0000024671;Note=Plexin-B1
O431571206126411621249DomainNote=IPT/TIG 2
O431571206126411621249DomainNote=IPT/TIG 2
O431571206126412521375DomainNote=IPT/TIG 3
O431571206126412521375DomainNote=IPT/TIG 3
O431571206126412531253GlycosylationNote=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16335952,ECO:0000269|PubMed:19159218,ECO:0000269|PubMed:19349973;Dbxref=PMID:16335952,PMID:19159218,PMID:19349973
O431571206126412531253GlycosylationNote=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16335952,ECO:0000269|PubMed:19159218,ECO:0000269|PubMed:19349973;Dbxref=PMID:16335952,PMID:19159218,PMID:19349973
O4315712061264201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O4315712061264201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157207621017302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157207621017302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O4315720762101202135ChainID=PRO_0000024671;Note=Plexin-B1
O4315720762101202135ChainID=PRO_0000024671;Note=Plexin-B1
O431572076210120642076HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210120642076HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210120842097HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210120842097HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210120992107HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210120992107HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210115122135Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O431572076210115122135Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
O43157369430380382Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430380382Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430385390Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430385390Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430392394Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430392394Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430397400Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430397400Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430405413Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430405413Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430416423Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430416423Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430426432Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430426432Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157369430202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157369430252377Disulfide bondOntology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O43157369430252377Disulfide bondOntology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O4315736943020479DomainNote=Sema;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O4315736943020479DomainNote=Sema;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O43157369430370374HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430370374HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157369430389389Natural variantID=VAR_050598;Note=R->W;Dbxref=dbSNP:rs34050056
O43157369430389389Natural variantID=VAR_050598;Note=R->W;Dbxref=dbSNP:rs34050056
O43157369430201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157369430201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157430473426432Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473426432Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473434436Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3OL2
O43157430473434436Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3OL2
O43157430473442448Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473442448Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473463469Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473463469Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5B4W
O43157430473202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157430473202135ChainID=PRO_0000024671;Note=Plexin-B1
O4315743047320479DomainNote=Sema;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O4315743047320479DomainNote=Sema;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00352
O43157430473201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157430473201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157676903677729Alternative sequenceID=VSP_011513;Note=In isoform 3. SPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGAS->VMETQQSLRALPPPSSSRPASTTSMTPPGSGSWKRRPWGQAPAPVWRAFRAPR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157676903677729Alternative sequenceID=VSP_011513;Note=In isoform 3. SPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTATASDISPGAS->VMETQQSLRALPPPSSSRPASTTSMTPPGSGSWKRRPWGQAPAPVWRAFRAPR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157676903688870Alternative sequenceID=VSP_011514;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157676903688870Alternative sequenceID=VSP_011514;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O431576769037302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O431576769037302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157676903202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157676903202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157676903678829Compositional biasNote=Pro-rich
O43157676903678829Compositional biasNote=Pro-rich
O43157676903753753Natural variantID=VAR_050599;Note=S->L;Dbxref=dbSNP:rs35592743
O43157676903753753Natural variantID=VAR_050599;Note=S->L;Dbxref=dbSNP:rs35592743
O43157676903201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157676903201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O431579039447302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O431579039447302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157903944202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157903944202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157903944201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157903944201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O431579449857302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O431579449857302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157944985202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157944985202135ChainID=PRO_0000024671;Note=Plexin-B1
O43157944985201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157944985201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157120612647302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157120612647302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O4315712061264202135ChainID=PRO_0000024671;Note=Plexin-B1
O4315712061264202135ChainID=PRO_0000024671;Note=Plexin-B1
O431571206126411621249DomainNote=IPT/TIG 2
O431571206126411621249DomainNote=IPT/TIG 2
O431571206126412521375DomainNote=IPT/TIG 3
O431571206126412521375DomainNote=IPT/TIG 3
O431571206126412531253GlycosylationNote=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16335952,ECO:0000269|PubMed:19159218,ECO:0000269|PubMed:19349973;Dbxref=PMID:16335952,PMID:19159218,PMID:19349973
O431571206126412531253GlycosylationNote=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16335952,ECO:0000269|PubMed:19159218,ECO:0000269|PubMed:19349973;Dbxref=PMID:16335952,PMID:19159218,PMID:19349973
O4315712061264201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O4315712061264201490Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O43157207621017302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O43157207621017302135Alternative sequenceID=VSP_011515;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10520995;Dbxref=PMID:10520995
O4315720762101202135ChainID=PRO_0000024671;Note=Plexin-B1
O4315720762101202135ChainID=PRO_0000024671;Note=Plexin-B1
O431572076210120642076HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210120642076HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210120842097HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210120842097HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210120992107HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210120992107HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3HM6
O431572076210115122135Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O431572076210115122135Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255


Top

SNVs in the skipped exons for PLXNB1

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
KIRCTCGA-B8-A54K-01exon_skip_383461
48450737484508844845084948450849Frame_Shift_DelT-p.N1992fs
LIHCTCGA-DD-A39Y-01exon_skip_383461
48450737484508844845084948450849Frame_Shift_DelT-p.N1992fs
LIHCTCGA-DD-A3A0-01exon_skip_383477
48452277484524454845230748452307Frame_Shift_DelG-p.Q1796fs
LIHCTCGA-DD-A1EG-01exon_skip_383477
48452277484524454845232348452323Frame_Shift_DelT-p.K1790fs
LIHCTCGA-DD-A3A0-01exon_skip_383507
48457755484578604845779548457795Frame_Shift_DelC-p.G1147fs
LIHCTCGA-DD-A3A0-01exon_skip_383507
48457755484578604845783248457832Frame_Shift_DelC-p.E1136fs
LIHCTCGA-DD-A1EG-0148459600484597724845968348459683Frame_Shift_DelC-p.E1047fs
LIHCTCGA-DD-A3A0-01exon_skip_383515
48460653484607754846074348460743Frame_Shift_DelG-p.P914fs
LIHCTCGA-DD-A1EG-01exon_skip_383515
48460653484607754846075748460757Frame_Shift_DelC-p.A910fs
LIHCTCGA-DD-A3A0-01exon_skip_383517
48460986484610834846107748461077Frame_Shift_DelC-p.G873fs
LIHCTCGA-DD-A3A0-01exon_skip_383519
48460986484616664846107748461077Frame_Shift_DelC-p.G873fs
SKCMTCGA-D9-A1JW-06exon_skip_383519
48460986484616664846113748461137Frame_Shift_DelT-p.D853fs
LIHCTCGA-DD-A1EG-01exon_skip_383519
48460986484616664846123648461236Frame_Shift_DelG-p.P820fs
LIHCTCGA-DD-A3A0-01exon_skip_383519
48460986484616664846129048461290Frame_Shift_DelG-p.P802fs
LIHCTCGA-DD-A1EG-01exon_skip_383519
48460986484616664846132348461323Frame_Shift_DelG-p.P791fs
LIHCTCGA-DD-A1EG-01exon_skip_383519
48460986484616664846149048461490Frame_Shift_DelG-p.P735fs
LIHCTCGA-DD-A3A0-01exon_skip_383519
48460986484616664846149048461490Frame_Shift_DelG-p.P735fs
LIHCTCGA-DD-A3A0-01exon_skip_383519
48460986484616664846151348461513Frame_Shift_DelC-p.A728fs
UCECTCGA-AP-A0LE-01exon_skip_383464
48451314484514864845145248451453Frame_Shift_Ins-Cp.G1880fs
UCECTCGA-B5-A0JR-01exon_skip_383519
48460986484616664846160048461601Frame_Shift_Ins-Gp.P698fs
SARCTCGA-IS-A3KA-01exon_skip_383534
48462637484627934846275548462756Frame_Shift_Ins-GGCCACAp.G565fs
SARCTCGA-IS-A3KA-01exon_skip_383534
48462637484627934846275548462756Frame_Shift_Ins-GGCCACAp.R564fs
BLCATCGA-2F-A9KT-01exon_skip_383534
48462637484627934846278348462783Nonsense_MutationGCp.S555*
STADTCGA-BR-8078-01exon_skip_383470
48451705484517894845170448451704Splice_SiteCT.
STADTCGA-BR-8078-01exon_skip_383470
48451705484517894845170448451704Splice_SiteCTp.R1869_splice

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
HEC151_ENDOMETRIUM48451314484514864845145348451453Frame_Shift_DelC-p.G1880fs
22RV1_PROSTATE48460986484610834846104248461042Frame_Shift_DelG-p.L885fs
22RV1_PROSTATE48460986484616664846104248461042Frame_Shift_DelG-p.L885fs
C33A_CERVIX48460986484616664846112248461122Frame_Shift_DelC-p.G858fs
HEC265_ENDOMETRIUM48451314484514864845145248451453Frame_Shift_Ins-Cp.G1880fs
MFE319_ENDOMETRIUM48460986484616664846112148461122Frame_Shift_Ins-Cp.G858fs
RL952_ENDOMETRIUM48447131484472054844718348447183Missense_MutationGAp.A2084V
MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48450737484508844845080448450804Missense_MutationGAp.A2007V
JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48451314484514864845136348451363Missense_MutationCTp.R1910H
SW962_VULVA48451314484514864845137648451376Missense_MutationCAp.G1906W
HEC265_ENDOMETRIUM48451314484514864845139048451390Missense_MutationCTp.G1901D
HCC1599_BREAST48451314484514864845142048451420Missense_MutationTAp.D1891V
SNU1040_LARGE_INTESTINE48451705484517894845172448451724Missense_MutationCAp.Q1862H
MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48452277484524454845232748452327Missense_MutationTAp.Y1789F
KP3_PANCREAS48452277484524454845239448452394Missense_MutationCTp.V1767M
P31FUJ_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48452277484524454845239448452394Missense_MutationCTp.V1767M
HCC1438_LUNG48452277484524454845239948452399Missense_MutationTAp.Q1765L
LNCAPCLONEFGC_PROSTATE48453647484537134845365848453658Missense_MutationTCp.T1697A
BICR18_UPPER_AERODIGESTIVE_TRACT48455079484552274845508448455084Missense_MutationCTp.M1510I
LOVO_LARGE_INTESTINE48455079484552274845510448455104Missense_MutationCAp.V1504F
C33A_CERVIX48455079484552274845520848455208Missense_MutationCTp.R1469H
SNU1_STOMACH48456992484571684845711548457115Missense_MutationGAp.T1224M
HEC108_ENDOMETRIUM48456992484571684845713948457139Missense_MutationCTp.R1216Q
MUGCHOR1_BONE48456992484571684845714048457140Missense_MutationGAp.R1216W
RF48_STOMACH48457755484578604845778648457786Missense_MutationCTp.R1150H
PACADD137_PANCREAS48459600484597724845966248459662Missense_MutationGAp.R1054W
CMLT1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48459600484597724845968048459680Missense_MutationGAp.R1048C
PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48460653484607754846069348460693Missense_MutationCTp.R931Q
CW2_LARGE_INTESTINE48460653484607754846072348460723Missense_MutationCTp.G921D
SNGM_ENDOMETRIUM48460986484610834846102448461024Missense_MutationGTp.L891I
SNGM_ENDOMETRIUM48460986484616664846102448461024Missense_MutationGTp.L891I
BICR18_UPPER_AERODIGESTIVE_TRACT48460986484610834846103248461032Missense_MutationGAp.P888L
BICR18_UPPER_AERODIGESTIVE_TRACT48460986484616664846103248461032Missense_MutationGAp.P888L
DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48460986484610834846103248461032Missense_MutationGAp.P888L
DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48460986484616664846103248461032Missense_MutationGAp.P888L
SNU1040_LARGE_INTESTINE48460986484610834846104848461048Missense_MutationCTp.A883T
SNU1040_LARGE_INTESTINE48460986484616664846104848461048Missense_MutationCTp.A883T
CAMA1_BREAST48460986484610834846107548461075Missense_MutationCGp.D874H
CAMA1_BREAST48460986484616664846107548461075Missense_MutationCGp.D874H
C33A_CERVIX48460986484616664846115548461155Missense_MutationCTp.G847D
LS411N_LARGE_INTESTINE48460986484616664846119848461198Missense_MutationCAp.G833C
NUGC2_STOMACH48460986484616664846128248461282Missense_MutationGAp.P805S
CMLT1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48460986484616664846131448461314Missense_MutationGAp.P794L
WM793_SKIN48460986484616664846137848461378Missense_MutationGAp.P773S
FARAGE_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48460986484616664846139348461393Missense_MutationGAp.P768S
COLO699_LUNG48460986484616664846160048461600Missense_MutationTGp.K699Q
D341MED_CENTRAL_NERVOUS_SYSTEM48460986484616664846160048461600Missense_MutationTGp.K699Q
HCC2108_LUNG48460986484616664846160048461600Missense_MutationTGp.K699Q
SEKI_SKIN48460986484616664846160048461600Missense_MutationTGp.K699Q
YAMATO_SOFT_TISSUE48460986484616664846160048461600Missense_MutationTGp.K699Q
CAL120_BREAST48460986484616664846160048461600Missense_MutationTCp.K699E
MESSA_SOFT_TISSUE48462637484627934846266448462664Missense_MutationCTp.E595K
OVK18_OVARY48463514484636144846355648463556Missense_MutationGAp.A493V
PECAPJ49_UPPER_AERODIGESTIVE_TRACT48463514484636144846361048463610Missense_MutationAGp.L475P
MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48464174484643564846422048464220Missense_MutationCAp.G415V
CA46_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48464174484643564846423048464230Missense_MutationTCp.M412V
SNUC1_LARGE_INTESTINE48464174484643564846429948464299Missense_MutationGAp.R389W
KU1919_URINARY_TRACT48464174484643564846433248464332Missense_MutationCAp.G378C
HEC50B_ENDOMETRIUM48464174484643564846433748464337Missense_MutationGAp.P376L
59M_OVARY48459600484597724845960148459601Splice_SiteGAp.S1074L
IGR1_SKIN48462637484627934846263848462638Splice_SiteGAp.A603A
NCIH2052_PLEURA48462637484627934846279248462792Splice_SiteACp.V552G
COLO678_LARGE_INTESTINE48462637484627934846279248462792Splice_SiteACp.V552G
HCT116_LARGE_INTESTINE48462637484627934846279248462792Splice_SiteACp.V552G

Top

Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for PLXNB1

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value

Top

Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PLXNB1


Top

Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PLXNB1


Top

RelatedDrugs for PLXNB1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for PLXNB1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource