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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in TCGA

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Exon skipping events with PSIs in GTEx

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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SNVs in the skipped exons with depth of coverage

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

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Related drugs with this gene

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Related diseases with this gene

Gene summary for PDE9A

check button Gene summary
Gene informationGene symbol

PDE9A

Gene ID

5152

Gene namephosphodiesterase 9A
SynonymsHSPDE9A2
Cytomap

21q22.3

Type of geneprotein-coding
Descriptionhigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9ACGMP-specific 3',5'-cyclic phosphodiesterase type 9phosphodiesterase PDE9A21
Modification date20180519
UniProtAcc

O76083

ContextPubMed: PDE9A [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
PDE9A

GO:0046068

cGMP metabolic process

9624146

PDE9A

GO:0046069

cGMP catabolic process

25799991


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Exon skipping events across known transcript of Ensembl for PDE9A from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Gene isoform structures and expression levels for PDE9A

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


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Exon skipping events with PSIs in TCGA for PDE9A

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_3602152144073922:44073993:44106301:44106372:44108026:4410810444106301:44106372ENSG00000160191.13ENST00000335512.4,ENST00000486902.1,ENST00000470987.1,ENST00000539837.1,ENST00000472401.1,ENST00000380328.2,ENST00000291539.6
exon_skip_3602162144073922:44073993:44106301:44106372:44119077:4411912144106301:44106372ENSG00000160191.13ENST00000468805.1,ENST00000328862.6,ENST00000398236.3
exon_skip_3602182144073922:44073993:44108026:44108104:44119077:4411912144108026:44108104ENSG00000160191.13ENST00000335440.6,ENST00000398225.3,ENST00000398234.3,ENST00000497805.1
exon_skip_3602262144073864:44073993:44119077:44119121:44151879:4415205944119077:44119121ENSG00000160191.13ENST00000398232.3
exon_skip_3602272144073922:44073993:44119077:44119121:44152179:4415223444119077:44119121ENSG00000160191.13ENST00000398224.3
exon_skip_3602292144073922:44073993:44119077:44119121:44153465:4415353644119077:44119121ENSG00000160191.13ENST00000349112.3,ENST00000495521.1
exon_skip_3602372144106306:44106372:44108026:44108104:44119077:4411912144108026:44108104ENSG00000160191.13ENST00000335512.4,ENST00000486902.1,ENST00000467162.1,ENST00000291539.6
exon_skip_3602432144108026:44108104:44117524:44117600:44119077:4411912144117524:44117600ENSG00000160191.13ENST00000470987.1,ENST00000472401.1,ENST00000380328.2
exon_skip_3602462144108026:44108104:44119077:44119121:44152179:4415223444119077:44119121ENSG00000160191.13ENST00000335512.4,ENST00000398234.3,ENST00000467162.1
exon_skip_3602472144108026:44108104:44119077:44119121:44153465:4415353644119077:44119121ENSG00000160191.13ENST00000335440.6
exon_skip_3602552144119077:44119121:44144665:44144744:44152179:4415223444144665:44144744ENSG00000160191.13ENST00000462571.1
exon_skip_3602592144119077:44119121:44151879:44152059:44152179:4415223444151879:44152059ENSG00000160191.13ENST00000398225.3,ENST00000398232.3,ENST00000328862.6,ENST00000291539.6
exon_skip_3602612144119077:44119121:44151879:44152059:44153465:4415353644151879:44152059ENSG00000160191.13ENST00000497805.1
exon_skip_3602632144119077:44119121:44152179:44152234:44153465:4415353644152179:44152234ENSG00000160191.13ENST00000335512.4,ENST00000470987.1,ENST00000398224.3,ENST00000398234.3,ENST00000467162.1,ENST00000460905.1,ENST00000398236.3
exon_skip_3602662144119077:44119121:44153465:44153536:44163885:4416397044153465:44153536ENSG00000160191.13ENST00000335440.6,ENST00000468805.1,ENST00000380328.2,ENST00000349112.3
exon_skip_3602682144151879:44152059:44152179:44152234:44153465:4415353644152179:44152234ENSG00000160191.13ENST00000490803.1,ENST00000398225.3,ENST00000398232.3,ENST00000495343.1,ENST00000328862.6,ENST00000291539.6
exon_skip_3602712144153467:44153536:44163885:44163970:44171225:4417130744163885:44163970ENSG00000160191.13ENST00000335512.4,ENST00000398227.3,ENST00000490803.1,ENST00000467403.1,ENST00000335440.6,ENST00000470987.1,ENST00000398229.3,ENST00000539837.1,ENST00000398225.3,ENST00000468805.1,ENST00000398224.3,ENST00000380328.2,ENST00000398234.3,ENST00000349112.3,ENS
exon_skip_3602732144163885:44163970:44171225:44171307:44174099:4417417444171225:44171307ENSG00000160191.13ENST00000335512.4,ENST00000398227.3,ENST00000490803.1,ENST00000467403.1,ENST00000335440.6,ENST00000470987.1,ENST00000398229.3,ENST00000539837.1,ENST00000398225.3,ENST00000468805.1,ENST00000398224.3,ENST00000380328.2,ENST00000398234.3,ENST00000349112.3,ENS
exon_skip_3602772144174099:44174174:44179108:44179195:44180437:4418054244179108:44179195ENSG00000160191.13ENST00000335512.4,ENST00000398227.3,ENST00000490803.1,ENST00000467403.1,ENST00000335440.6,ENST00000470987.1,ENST00000398229.3,ENST00000539837.1,ENST00000398225.3,ENST00000460989.1,ENST00000468805.1,ENST00000398224.3,ENST00000380328.2,ENST00000398234.3,ENS
exon_skip_3602822144185490:44185604:44188297:44188402:44189136:4418926544188297:44188402ENSG00000160191.13ENST00000335512.4,ENST00000398227.3,ENST00000490803.1,ENST00000467403.1,ENST00000335440.6,ENST00000470987.1,ENST00000398229.3,ENST00000539837.1,ENST00000398225.3,ENST00000460989.1,ENST00000468805.1,ENST00000398224.3,ENST00000380328.2,ENST00000398234.3,ENS
exon_skip_3602852144190812:44190908:44192548:44192630:44195389:4419561644192548:44192630ENSG00000160191.13ENST00000335512.4,ENST00000398227.3,ENST00000490803.1,ENST00000467403.1,ENST00000335440.6,ENST00000470987.1,ENST00000398229.3,ENST00000539837.1,ENST00000398225.3,ENST00000460989.1,ENST00000468805.1,ENST00000398224.3,ENST00000380328.2,ENST00000398234.3,ENS

check button PSI values of skipped exons in TCGA.
psi tcga

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Exon skipping events with PSIs in GTEx for PDE9A

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_3602152144073922:44073993:44106301:44106372:44108026:4410810444106301:44106372ENSG00000160191.13ENST00000472401.1,ENST00000335512.4,ENST00000539837.1,ENST00000470987.1,ENST00000291539.6,ENST00000486902.1,ENST00000380328.2
exon_skip_3602162144073922:44073993:44106301:44106372:44119077:4411912144106301:44106372ENSG00000160191.13ENST00000398236.3,ENST00000468805.1,ENST00000328862.6
exon_skip_3602182144073922:44073993:44108026:44108104:44119077:4411912144108026:44108104ENSG00000160191.13ENST00000398234.3,ENST00000335440.6,ENST00000398225.3,ENST00000497805.1
exon_skip_3602202144073922:44073993:44108026:44108104:44153465:4415353644108026:44108104ENSG00000160191.13ENST00000398229.3
exon_skip_3602262144073864:44073993:44119077:44119121:44151879:4415205944119077:44119121ENSG00000160191.13ENST00000398232.3
exon_skip_3602272144073922:44073993:44119077:44119121:44152179:4415223444119077:44119121ENSG00000160191.13ENST00000398224.3
exon_skip_3602292144073922:44073993:44119077:44119121:44153465:4415353644119077:44119121ENSG00000160191.13ENST00000495521.1,ENST00000349112.3
exon_skip_3602312144073864:44073993:44151879:44152059:44152179:4415223444151879:44152059ENSG00000160191.13ENST00000490803.1
exon_skip_3602332144073922:44073993:44152179:44152234:44153465:4415353644152179:44152234ENSG00000160191.13ENST00000467403.1
exon_skip_3602372144106306:44106372:44108026:44108104:44119077:4411912144108026:44108104ENSG00000160191.13ENST00000335512.4,ENST00000291539.6,ENST00000486902.1,ENST00000467162.1
exon_skip_3602432144108026:44108104:44117524:44117600:44119077:4411912144117524:44117600ENSG00000160191.13ENST00000472401.1,ENST00000470987.1,ENST00000380328.2
exon_skip_3602462144108026:44108104:44119077:44119121:44152179:4415223444119077:44119121ENSG00000160191.13ENST00000335512.4,ENST00000398234.3,ENST00000467162.1
exon_skip_3602472144108026:44108104:44119077:44119121:44153465:4415353644119077:44119121ENSG00000160191.13ENST00000335440.6
exon_skip_3602592144119077:44119121:44151879:44152059:44152179:4415223444151879:44152059ENSG00000160191.13ENST00000291539.6,ENST00000398232.3,ENST00000328862.6,ENST00000398225.3
exon_skip_3602612144119077:44119121:44151879:44152059:44153465:4415353644151879:44152059ENSG00000160191.13ENST00000497805.1
exon_skip_3602632144119077:44119121:44152179:44152234:44153465:4415353644152179:44152234ENSG00000160191.13ENST00000460905.1,ENST00000335512.4,ENST00000470987.1,ENST00000398234.3,ENST00000398236.3,ENST00000398224.3,ENST00000467162.1
exon_skip_3602662144119077:44119121:44153465:44153536:44163885:4416397044153465:44153536ENSG00000160191.13ENST00000380328.2,ENST00000468805.1,ENST00000335440.6,ENST00000349112.3
exon_skip_3602682144151879:44152059:44152179:44152234:44153465:4415353644152179:44152234ENSG00000160191.13ENST00000291539.6,ENST00000490803.1,ENST00000398232.3,ENST00000328862.6,ENST00000398225.3,ENST00000495343.1
exon_skip_3602712144153467:44153536:44163885:44163970:44171225:4417130744163885:44163970ENSG00000160191.13ENST00000460905.1,ENST00000335512.4,ENST00000539837.1,ENST00000470987.1,ENST00000291539.6,ENST00000490803.1,ENST00000380328.2,ENST00000398232.3,ENST00000462571.1,ENST00000398234.3,ENST00000398236.3,ENST00000468805.1,ENST00000328862.6,ENST00000335440.6,ENS
exon_skip_3602732144163885:44163970:44171225:44171307:44174099:4417417444171225:44171307ENSG00000160191.13ENST00000460905.1,ENST00000335512.4,ENST00000539837.1,ENST00000470987.1,ENST00000291539.6,ENST00000490803.1,ENST00000380328.2,ENST00000398232.3,ENST00000462571.1,ENST00000398234.3,ENST00000398236.3,ENST00000468805.1,ENST00000328862.6,ENST00000335440.6,ENS
exon_skip_3602772144174099:44174174:44179108:44179195:44180437:4418054244179108:44179195ENSG00000160191.13ENST00000335512.4,ENST00000539837.1,ENST00000470987.1,ENST00000291539.6,ENST00000490803.1,ENST00000380328.2,ENST00000495521.1,ENST00000398232.3,ENST00000462571.1,ENST00000398234.3,ENST00000398236.3,ENST00000468805.1,ENST00000328862.6,ENST00000335440.6,ENS
exon_skip_3602822144185490:44185604:44188297:44188402:44189136:4418926544188297:44188402ENSG00000160191.13ENST00000335512.4,ENST00000539837.1,ENST00000470987.1,ENST00000291539.6,ENST00000490803.1,ENST00000380328.2,ENST00000495521.1,ENST00000398232.3,ENST00000462571.1,ENST00000398234.3,ENST00000398236.3,ENST00000468805.1,ENST00000328862.6,ENST00000335440.6,ENS
exon_skip_3602852144190812:44190908:44192548:44192630:44195389:4419561644192548:44192630ENSG00000160191.13ENST00000335512.4,ENST00000539837.1,ENST00000470987.1,ENST00000291539.6,ENST00000490803.1,ENST00000380328.2,ENST00000495521.1,ENST00000398232.3,ENST00000462571.1,ENST00000398234.3,ENST00000398236.3,ENST00000468805.1,ENST00000328862.6,ENST00000335440.6,ENS

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for PDE9A

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000002915394410630144106372Frame-shift
ENST000002915394415217944152234Frame-shift
ENST000002915394416388544163970Frame-shift
ENST000002915394417122544171307Frame-shift
ENST000002915394419254844192630Frame-shift
ENST000002915394410802644108104In-frame
ENST000002915394415187944152059In-frame
ENST000002915394417910844179195In-frame
ENST000002915394418829744188402In-frame

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000002915394410630144106372Frame-shift
ENST000002915394415217944152234Frame-shift
ENST000002915394416388544163970Frame-shift
ENST000002915394417122544171307Frame-shift
ENST000002915394419254844192630Frame-shift
ENST000002915394410802644108104In-frame
ENST000002915394415187944152059In-frame
ENST000002915394417910844179195In-frame
ENST000002915394418829744188402In-frame

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Infer the effects of exon skipping event on protein functional features for PDE9A

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST00000291539207559344108026441081042012784772
ENST000002915392075593441518794415205932350287147
ENST0000029153920755934417910844179195871957270299
ENST000002915392075593441882974418840214171521452487

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST00000291539207559344108026441081042012784772
ENST000002915392075593441518794415205932350287147
ENST0000029153920755934417910844179195871957270299
ENST000002915392075593441882974418840214171521452487

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature


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SNVs in the skipped exons for PDE9A

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
LIHCTCGA-G3-A3CJ-01exon_skip_360216
exon_skip_360215
44106302441063724410636044106360Frame_Shift_DelC-p.T43fs
BRCATCGA-A8-A09K-01exon_skip_360226
exon_skip_360246
exon_skip_360247
exon_skip_360227
exon_skip_360229
44119078441191214411909944119099Frame_Shift_DelT-p.V81fs
LIHCTCGA-DD-A39Y-01exon_skip_360261
exon_skip_360259
44151880441520594415196644151966Frame_Shift_DelC-p.P117fs
LIHCTCGA-DD-A3A0-01exon_skip_360271
44163886441639704416394344163943Frame_Shift_DelG-p.R209fs
LIHCTCGA-G3-A3CJ-01exon_skip_360273
44171226441713074417123044171230Frame_Shift_DelA-p.N220fs
LIHCTCGA-DD-A1EG-01exon_skip_360282
44188298441884024418838244188382Frame_Shift_DelT-p.L481fs
BLCATCGA-GV-A3QI-01exon_skip_360218
exon_skip_360237
44108027441081044410808744108088Frame_Shift_Ins-Cp.M67fs
BLCATCGA-GV-A3QI-01exon_skip_360218
exon_skip_360237
44108027441081044410808744108088Frame_Shift_Ins-Cp.P68fs
COADTCGA-G4-6309-01exon_skip_360285
44192549441926304419259644192597Frame_Shift_Ins-AGp.S444fs
DLBCTCGA-G8-6324-01exon_skip_360226
exon_skip_360246
exon_skip_360247
exon_skip_360227
exon_skip_360229
44119078441191214411912044119120Nonsense_MutationCTp.R113X
SKCMTCGA-EE-A3AD-06exon_skip_360273
44171226441713074417128144171281Nonsense_MutationCTp.R237*
LIHCTCGA-DD-AAC8-01exon_skip_360285
44192549441926304419259744192597Nonsense_MutationATp.R579X
UCSTCGA-ND-A4WC-01exon_skip_360263
exon_skip_360268
44152180441522344415223644152236Splice_SiteTC.
BRCATCGA-BH-A0DZ-01exon_skip_360266
44153466441535364415346544153465Splice_SiteGAe7-1
HNSCTCGA-BA-6870-01exon_skip_360266
44153466441535364415346544153465Splice_SiteGAp.R166_splice

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description
PDE9A_44119077_44119121_44152179_44152234_44153465_44153536_TCGA-ND-A4WC-01Sample: TCGA-ND-A4WC-01
Cancer type: UCS
ESID: exon_skip_360268
Skipped exon start: 44152180
Skipped exon end: 44152234
Mutation start: 44152236
Mutation end: 44152236
Mutation type: Splice_Site
Reference seq: T
Mutation seq: C
AAchange: .
exon_skip_149665_UCS_TCGA-ND-A4WC-01.png
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exon_skip_299626_UCS_TCGA-ND-A4WC-01.png
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exon_skip_344918_UCS_TCGA-ND-A4WC-01.png
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exon_skip_360263_UCS_TCGA-ND-A4WC-01.png
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exon_skip_382353_UCS_TCGA-ND-A4WC-01.png
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exon_skip_385882_UCS_TCGA-ND-A4WC-01.png
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exon_skip_443509_UCS_TCGA-ND-A4WC-01.png
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exon_skip_45962_UCS_TCGA-ND-A4WC-01.png
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exon_skip_48320_UCS_TCGA-ND-A4WC-01.png
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exon_skip_484856_UCS_TCGA-ND-A4WC-01.png
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exon_skip_59444_UCS_TCGA-ND-A4WC-01.png
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PDE9A_44119077_44119121_44151879_44152059_44153465_44153536_TCGA-DD-A39Y-01Sample: TCGA-DD-A39Y-01
Cancer type: LIHC
ESID: exon_skip_360259
Skipped exon start: 44151880
Skipped exon end: 44152059
Mutation start: 44151966
Mutation end: 44151966
Mutation type: Frame_Shift_Del
Reference seq: C
Mutation seq: -
AAchange: p.P117fs
exon_skip_105023_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_101824_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_106032_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_106378_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_106523_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_106524_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_109527_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_109529_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_110000_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_11029_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_111893_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_111894_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_112042_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_112647_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_114045_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_114046_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_114565_LIHC_TCGA-DD-A39Y-01.png
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exon_skip_11916_LIHC_TCGA-DD-A39Y-01.png
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PDE9A_44119077_44119121_44151879_44152059_44152179_44152234_TCGA-DD-A39Y-01Sample: TCGA-DD-A39Y-01
Cancer type: LIHC
ESID: exon_skip_360259
Skipped exon start: 44151880
Skipped exon end: 44152059
Mutation start: 44151966
Mutation end: 44151966
Mutation type: Frame_Shift_Del
Reference seq: C
Mutation seq: -
AAchange: p.P117fs
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check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
OC316_OVARY44153466441535364415351744153517Frame_Shift_DelC-p.V183fs
OC314_OVARY44153466441535364415351744153517Frame_Shift_DelC-p.V183fs
LS411N_LARGE_INTESTINE44106302441063724410632144106321Missense_MutationGAp.C30Y
GP2D_LARGE_INTESTINE44106302441063724410634744106347Missense_MutationTCp.F39L
GP5D_LARGE_INTESTINE44106302441063724410634744106347Missense_MutationTCp.F39L
CCRFCEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE44151880441520594415190744151907Missense_MutationGAp.S97N
NCIH838_LUNG44151880441520594415195444151954Missense_MutationGTp.G113C
A2058_SKIN44151880441520594415196044151960Missense_MutationGAp.E115K
IM95_STOMACH44151880441520594415202144152021Missense_MutationCTp.P135L
TE15_OESOPHAGUS44151880441520594415202144152021Missense_MutationCTp.P135L
C84_LARGE_INTESTINE44151880441520594415202244152023Missense_MutationCCGAp.Q136K
SCLC22H_LUNG44151880441520594415202544152025Missense_MutationGTp.Q136H
SCLC21H_LUNG44151880441520594415202544152025Missense_MutationGTp.Q136H
CAL72_BONE44151880441520594415205144152051Missense_MutationTCp.I145T
NCIH1155_LUNG44153466441535364415352844153528Missense_MutationGAp.R187H
SW1353_BONE44163886441639704416389544163895Missense_MutationTCp.L193P
NCIH2110_LUNG44163886441639704416394344163943Missense_MutationGTp.R209M
SNUC5_LARGE_INTESTINE44179109441791954417911544179115Missense_MutationACp.S273R
MM383_SKIN44188298441884024418835144188351Missense_MutationGAp.M470I
SKMEL31_SKIN44192549441926304419259544192595Missense_MutationCTp.S578F
JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE44171226441713074417128144171281Nonsense_MutationCTp.R237*
HEC251_ENDOMETRIUM44188298441884024418829844188298Splice_SiteCAp.L453M

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for PDE9A

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PDE9A


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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for PDE9A


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RelatedDrugs for PDE9A

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PDE9A

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
PDE9AC0005586Bipolar Disorder1PSYGENET