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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for MUC6 |
 Gene summary |
| Gene information | Gene symbol | MUC6 | Gene ID | 4588 |
| Gene name | mucin 6, oligomeric mucus/gel-forming | |
| Synonyms | MUC-6 | |
| Cytomap | 11p15.5 | |
| Type of gene | protein-coding | |
| Description | mucin-6gastric mucin-6 | |
| Modification date | 20180329 | |
| UniProtAcc | Q6W4X9 | |
| Context | PubMed: MUC6 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for MUC6 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for MUC6 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for MUC6 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_67703 | 11 | 1013472:1013633:1013795:1013898:1015761:1015883 | 1013795:1013898 | ENSG00000184956.11 | ENST00000532016.1 |
| exon_skip_67706 | 11 | 1013472:1013633:1013898:1014001:1015761:1015883 | 1013898:1014001 | ENSG00000184956.11 | ENST00000421673.2 |
| exon_skip_67722 | 11 | 1013898:1014001:1015761:1018770:1019274:1019496 | 1015761:1018770 | ENSG00000184956.11 | ENST00000421673.2 |
| exon_skip_67734 | 11 | 1018035:1018770:1019274:1019496:1020089:1020257 | 1019274:1019496 | ENSG00000184956.11 | ENST00000421673.2 |
| exon_skip_67735 | 11 | 1029494:1029615:1030212:1030335:1030572:1030780 | 1030212:1030335 | ENSG00000184956.11 | ENST00000421673.2 |
| exon_skip_67736 | 11 | 1030212:1030335:1030572:1030780:1030946:1031056 | 1030572:1030780 | ENSG00000184956.11 | ENST00000421673.2 |
| exon_skip_67737 | 11 | 1030946:1031056:1031168:1031259:1031606:1031733 | 1031168:1031259 | ENSG00000184956.11 | ENST00000421673.2 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for MUC6 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_67703 | 11 | 1013472:1013633:1013795:1013898:1015761:1015883 | 1013795:1013898 | ENSG00000184956.11 | ENST00000532016.1 |
| exon_skip_67706 | 11 | 1013472:1013633:1013898:1014001:1015761:1015883 | 1013898:1014001 | ENSG00000184956.11 | ENST00000421673.2 |
| exon_skip_67722 | 11 | 1013898:1014001:1015761:1018770:1019274:1019496 | 1015761:1018770 | ENSG00000184956.11 | ENST00000421673.2 |
| exon_skip_67734 | 11 | 1018035:1018770:1019274:1019496:1020089:1020257 | 1019274:1019496 | ENSG00000184956.11 | ENST00000421673.2 |
| exon_skip_67736 | 11 | 1030212:1030335:1030572:1030780:1030946:1031056 | 1030572:1030780 | ENSG00000184956.11 | ENST00000421673.2 |
| exon_skip_67737 | 11 | 1030946:1031056:1031168:1031259:1031606:1031733 | 1031168:1031259 | ENSG00000184956.11 | ENST00000421673.2 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for MUC6 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
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Infer the effects of exon skipping event on protein functional features for MUC6 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for MUC6 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| BRCA | TCGA-BH-A0H3-01 | exon_skip_67722 | 1015762 | 1018770 | 1015877 | 1015880 | Frame_Shift_Del | AGGG | - | p.H2307fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_67722 | 1015762 | 1018770 | 1015913 | 1015913 | Frame_Shift_Del | G | - | p.P2296fs |
| STAD | TCGA-BR-4361-01 | exon_skip_67722 | 1015762 | 1018770 | 1015927 | 1015927 | Frame_Shift_Del | C | - | p.V2292fs |
| STAD | TCGA-VQ-A8DZ-01 | exon_skip_67722 | 1015762 | 1018770 | 1015942 | 1015943 | Frame_Shift_Del | AC | - | p.2287_2287del |
| STAD | TCGA-VQ-A8DZ-01 | exon_skip_67722 | 1015762 | 1018770 | 1015942 | 1015943 | Frame_Shift_Del | AC | - | p.VS2286fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_67722 | 1015762 | 1018770 | 1016161 | 1016161 | Frame_Shift_Del | G | - | p.H2214fs |
| ESCA | TCGA-ZR-A9CJ-01 | exon_skip_67722 | 1015762 | 1018770 | 1016221 | 1016224 | Frame_Shift_Del | CAGA | - | p.2193_2194del |
| ESCA | TCGA-ZR-A9CJ-01 | exon_skip_67722 | 1015762 | 1018770 | 1016221 | 1016224 | Frame_Shift_Del | CAGA | - | p.S2193fs |
| ESCA | TCGA-ZR-A9CJ-01 | exon_skip_67722 | 1015762 | 1018770 | 1016221 | 1016224 | Frame_Shift_Del | CAGA | - | p.SA2193fs |
| ESCA | TCGA-2H-A9GQ-01 | exon_skip_67722 | 1015762 | 1018770 | 1016373 | 1016376 | Frame_Shift_Del | GAAG | - | p.S2142fs |
| ESCA | TCGA-2H-A9GQ-01 | exon_skip_67722 | 1015762 | 1018770 | 1016373 | 1016376 | Frame_Shift_Del | GAAG | - | p.SS2142fs |
| STAD | TCGA-VQ-A94T-01 | exon_skip_67722 | 1015762 | 1018770 | 1016374 | 1016377 | Frame_Shift_Del | AAGA | - | p.2142_2143del |
| STAD | TCGA-VQ-A94T-01 | exon_skip_67722 | 1015762 | 1018770 | 1016374 | 1016377 | Frame_Shift_Del | AAGA | - | p.SS2142fs |
| UCEC | TCGA-D1-A102-01 | exon_skip_67722 | 1015762 | 1018770 | 1016483 | 1016483 | Frame_Shift_Del | A | - | p.P2106fs |
| STAD | TCGA-BR-8081-01 | exon_skip_67722 | 1015762 | 1018770 | 1016540 | 1016543 | Frame_Shift_Del | GAAG | - | p.2087_2088del |
| STAD | TCGA-BR-8081-01 | exon_skip_67722 | 1015762 | 1018770 | 1016540 | 1016543 | Frame_Shift_Del | GAAG | - | p.F2087fs |
| ESCA | TCGA-JY-A6FH-01 | exon_skip_67722 | 1015762 | 1018770 | 1016549 | 1016561 | Frame_Shift_Del | AGAGGCTGTAGCT | - | p.2081_2085del |
| ESCA | TCGA-JY-A6FH-01 | exon_skip_67722 | 1015762 | 1018770 | 1016549 | 1016561 | Frame_Shift_Del | AGAGGCTGTAGCT | - | p.TATAS2080fs |
| STAD | TCGA-VQ-A8DV-01 | exon_skip_67722 | 1015762 | 1018770 | 1016693 | 1016693 | Frame_Shift_Del | G | - | p.A2036fs |
| STAD | TCGA-VQ-A8DV-01 | exon_skip_67722 | 1015762 | 1018770 | 1016693 | 1016693 | Frame_Shift_Del | G | - | p.S2037fs |
| STAD | TCGA-D7-6519-01 | exon_skip_67722 | 1015762 | 1018770 | 1016732 | 1016733 | Frame_Shift_Del | TG | - | p.2023_2024del |
| STAD | TCGA-CD-A4MH-01 | exon_skip_67722 | 1015762 | 1018770 | 1016750 | 1016760 | Frame_Shift_Del | CACCAAGGAGG | - | p.T2014fs |
| STAD | TCGA-RD-A7BT-01 | exon_skip_67722 | 1015762 | 1018770 | 1016756 | 1016756 | Frame_Shift_Del | G | - | p.L2016fs |
| STAD | TCGA-FP-8211-01 | exon_skip_67722 | 1015762 | 1018770 | 1016973 | 1016974 | Frame_Shift_Del | GT | - | p.1943_1943del |
| STAD | TCGA-FP-8211-01 | exon_skip_67722 | 1015762 | 1018770 | 1016973 | 1016974 | Frame_Shift_Del | GT | - | p.T1943fs |
| STAD | TCGA-BR-A4PE-01 | exon_skip_67722 | 1015762 | 1018770 | 1017061 | 1017061 | Frame_Shift_Del | T | - | p.T1914fs |
| STAD | TCGA-HU-A4GX-01 | exon_skip_67722 | 1015762 | 1018770 | 1017323 | 1017324 | Frame_Shift_Del | AT | - | p.1826_1827del |
| UCEC | TCGA-A5-A0GW-01 | exon_skip_67722 | 1015762 | 1018770 | 1017620 | 1017620 | Frame_Shift_Del | T | - | p.T1727fs |
| UCEC | TCGA-A5-A0GH-01 | exon_skip_67722 | 1015762 | 1018770 | 1017721 | 1017721 | Frame_Shift_Del | G | - | p.L1694fs |
| STAD | TCGA-D7-6526-01 | exon_skip_67722 | 1015762 | 1018770 | 1017954 | 1017961 | Frame_Shift_Del | ACGTGAGT | - | p.T1614fs |
| STAD | TCGA-IN-7806-01 | exon_skip_67722 | 1015762 | 1018770 | 1018031 | 1018031 | Frame_Shift_Del | G | - | p.M1591X |
| STAD | TCGA-CD-8536-01 | exon_skip_67722 | 1015762 | 1018770 | 1018609 | 1018612 | Frame_Shift_Del | TGTA | - | p.1397_1398del |
| STAD | TCGA-CD-8536-01 | exon_skip_67722 | 1015762 | 1018770 | 1018609 | 1018612 | Frame_Shift_Del | TGTA | - | p.Y1397fs |
| STAD | TCGA-RD-A7BW-01 | exon_skip_67722 | 1015762 | 1018770 | 1018736 | 1018742 | Frame_Shift_Del | CGTTGTT | - | p.1354_1356del |
| STAD | TCGA-RD-A7BW-01 | exon_skip_67722 | 1015762 | 1018770 | 1018736 | 1018742 | Frame_Shift_Del | CGTTGTT | - | p.GTT1353fs |
| STAD | TCGA-HU-A4G2-01 | exon_skip_67734 | 1019275 | 1019496 | 1019329 | 1019329 | Frame_Shift_Del | G | - | p.R1326fs |
| BRCA | TCGA-BH-A0RX-01 | exon_skip_67734 | 1019275 | 1019496 | 1019367 | 1019368 | Frame_Shift_Del | GC | - | p.A1313fs |
| THCA | TCGA-KS-A4I5-01 | exon_skip_67736 | 1030573 | 1030780 | 1030583 | 1030583 | Frame_Shift_Del | G | - | p.P294fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_67736 | 1030573 | 1030780 | 1030678 | 1030678 | Frame_Shift_Del | G | - | p.Q263fs |
| STAD | TCGA-BR-6452-01 | exon_skip_67722 | 1015762 | 1018770 | 1016000 | 1016001 | Frame_Shift_Ins | - | TGAGA | p.Q2267fs |
| STAD | TCGA-BR-6452-01 | exon_skip_67722 | 1015762 | 1018770 | 1016001 | 1016002 | Frame_Shift_Ins | - | TGAGA | p.Q2267fs |
| UCEC | TCGA-A5-A0GW-01 | exon_skip_67722 | 1015762 | 1018770 | 1017617 | 1017618 | Frame_Shift_Ins | - | G | p.V1728fs |
| STAD | TCGA-R5-A7ZE-01 | exon_skip_67722 | 1015762 | 1018770 | 1018202 | 1018203 | Frame_Shift_Ins | - | T | p.H1533fs |
| STAD | TCGA-R5-A7ZE-01 | exon_skip_67722 | 1015762 | 1018770 | 1018202 | 1018203 | Frame_Shift_Ins | - | T | p.P1533fs |
| KICH | TCGA-KN-8429-01 | exon_skip_67722 | 1015762 | 1018770 | 1018550 | 1018551 | Frame_Shift_Ins | - | G | p.P1417fs |
| TGCT | TCGA-2G-AAFV-01 | exon_skip_67722 | 1015762 | 1018770 | 1018561 | 1018562 | Frame_Shift_Ins | - | C | p.S1414fs |
| ESCA | TCGA-L5-A4OR-01 | exon_skip_67722 | 1015762 | 1018770 | 1018731 | 1018732 | Frame_Shift_Ins | - | TGGCC | p.P1357fs |
| ESCA | TCGA-L5-A4OR-01 | exon_skip_67722 | 1015762 | 1018770 | 1018731 | 1018732 | Frame_Shift_Ins | - | TGGCC | p.T1357fs |
| KIRP | TCGA-GL-A4EM-01 | exon_skip_67734 | 1019275 | 1019496 | 1019461 | 1019462 | Frame_Shift_Ins | - | T | p.Q1281fs |
| HNSC | TCGA-CV-7427-01 | exon_skip_67722 | 1015762 | 1018770 | 1016425 | 1016425 | Nonsense_Mutation | G | A | p.Q2126* |
| LUSC | TCGA-34-2600-01 | exon_skip_67722 | 1015762 | 1018770 | 1017189 | 1017189 | Nonsense_Mutation | G | C | p.S1871* |
| HNSC | TCGA-CR-7402-01 | exon_skip_67722 | 1015762 | 1018770 | 1017714 | 1017714 | Nonsense_Mutation | G | T | p.S1696* |
| BRCA | TCGA-C8-A12X-01 | exon_skip_67722 | 1015762 | 1018770 | 1018368 | 1018368 | Nonsense_Mutation | G | T | p.S1478* |
| LIHC | TCGA-CC-A7IH-01 | exon_skip_67737 | 1031169 | 1031259 | 1031239 | 1031239 | Nonsense_Mutation | G | C | p.Y168* |
| LIHC | TCGA-CC-A7IH-01 | exon_skip_67737 | 1031169 | 1031259 | 1031239 | 1031239 | Nonsense_Mutation | G | C | p.Y168X |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| FLO1_OESOPHAGUS | 1015762 | 1018770 | 1018071 | 1018072 | Frame_Shift_Del | GA | - | p.S1577fs |
| NCIH1703_LUNG | 1013899 | 1014001 | 1013975 | 1013976 | Frame_Shift_Ins | - | T | p.E2356fs |
| CL34_LARGE_INTESTINE | 1015762 | 1018770 | 1018478 | 1018479 | Frame_Shift_Ins | - | GTCTGAGGGT | p.-1441fs |
| NCIH1703_LUNG | 1013899 | 1014001 | 1013906 | 1013906 | Missense_Mutation | C | T | p.A2379T |
| ISHIKAWAHERAKLIO02ER_ENDOMETRIUM | 1015762 | 1018770 | 1015843 | 1015843 | Missense_Mutation | T | C | p.T2320A |
| P30OHK_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1015852 | 1015852 | Missense_Mutation | G | A | p.R2317W |
| CTB1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1015879 | 1015879 | Missense_Mutation | G | A | p.P2308S |
| MELHO_SKIN | 1015762 | 1018770 | 1015896 | 1015896 | Missense_Mutation | T | A | p.N2302I |
| SNU324_PANCREAS | 1015762 | 1018770 | 1015906 | 1015906 | Missense_Mutation | G | T | p.P2299T |
| PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1015932 | 1015932 | Missense_Mutation | G | A | p.S2290L |
| KYAE1_OESOPHAGUS | 1015762 | 1018770 | 1016005 | 1016005 | Missense_Mutation | A | G | p.S2266P |
| HEC265_ENDOMETRIUM | 1015762 | 1018770 | 1016020 | 1016020 | Missense_Mutation | C | T | p.A2261T |
| WSUNHL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1016020 | 1016020 | Missense_Mutation | C | T | p.A2261T |
| HLFA_FIBROBLAST | 1015762 | 1018770 | 1016076 | 1016076 | Missense_Mutation | G | A | p.A2242V |
| NCIH2004RT_SOFT_TISSUE | 1015762 | 1018770 | 1016104 | 1016104 | Missense_Mutation | C | A | p.V2233L |
| C8166_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1016141 | 1016141 | Missense_Mutation | G | T | p.F2220L |
| NCIH23_LUNG | 1015762 | 1018770 | 1016175 | 1016175 | Missense_Mutation | C | T | p.R2209K |
| IHH4_THYROID | 1015762 | 1018770 | 1016226 | 1016226 | Missense_Mutation | A | T | p.V2192E |
| JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1016232 | 1016232 | Missense_Mutation | G | A | p.A2190V |
| BFTC909_KIDNEY | 1015762 | 1018770 | 1016299 | 1016299 | Missense_Mutation | C | T | p.A2168T |
| CW2_LARGE_INTESTINE | 1015762 | 1018770 | 1016305 | 1016305 | Missense_Mutation | C | T | p.V2166M |
| HS600T_FIBROBLAST | 1015762 | 1018770 | 1016373 | 1016373 | Missense_Mutation | G | A | p.S2143F |
| HEC59_ENDOMETRIUM | 1015762 | 1018770 | 1016383 | 1016383 | Missense_Mutation | T | C | p.T2140A |
| LNCAPCLONEFGC_PROSTATE | 1015762 | 1018770 | 1016491 | 1016491 | Missense_Mutation | A | G | p.S2104P |
| ROS50_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1016526 | 1016526 | Missense_Mutation | G | C | p.S2092C |
| NCIH446_LUNG | 1015762 | 1018770 | 1016590 | 1016590 | Missense_Mutation | T | A | p.T2071S |
| MOLT13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1016595 | 1016595 | Missense_Mutation | C | T | p.S2069N |
| HO1N1_UPPER_AERODIGESTIVE_TRACT | 1015762 | 1018770 | 1016598 | 1016598 | Missense_Mutation | G | C | p.T2068S |
| PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1016665 | 1016666 | Missense_Mutation | CG | TA | p.V2046I |
| EMCBAC2_LUNG | 1015762 | 1018770 | 1016947 | 1016947 | Missense_Mutation | C | A | p.A1952S |
| OV56_OVARY | 1015762 | 1018770 | 1017000 | 1017000 | Missense_Mutation | G | T | p.S1934Y |
| NCIH1755_LUNG | 1015762 | 1018770 | 1017099 | 1017099 | Missense_Mutation | C | G | p.G1901A |
| SBC3_LUNG | 1015762 | 1018770 | 1017100 | 1017100 | Missense_Mutation | C | T | p.G1901R |
| DL40_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1017103 | 1017103 | Missense_Mutation | T | C | p.S1900G |
| SNU81_LARGE_INTESTINE | 1015762 | 1018770 | 1017115 | 1017115 | Missense_Mutation | T | C | p.T1896A |
| HSC2_UPPER_AERODIGESTIVE_TRACT | 1015762 | 1018770 | 1017141 | 1017141 | Missense_Mutation | C | T | p.G1887E |
| CHLA258_BONE | 1015762 | 1018770 | 1017159 | 1017159 | Missense_Mutation | G | C | p.T1881S |
| KARPAS45_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1017163 | 1017163 | Missense_Mutation | G | A | p.P1880S |
| NCIH2373_PLEURA | 1015762 | 1018770 | 1017174 | 1017174 | Missense_Mutation | G | T | p.T1876N |
| C125PM_LARGE_INTESTINE | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| CASKI_CERVIX | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| ESO51_OESOPHAGUS | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| KARPAS384_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| MCC13_SKIN | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| MCC142_SKIN | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| MERO48A_LUNG | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| MERO95_LUNG | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| NCIH1915_LUNG | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| NCIH526_LUNG | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| NKL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| OACM51_OESOPHAGUS | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| PACADD119_PANCREAS | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| PACADD161_PANCREAS | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| SW756_CERVIX | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| UMUC14_URINARY_TRACT | 1015762 | 1018770 | 1017239 | 1017240 | Missense_Mutation | CG | TA | p.T1854I |
| VMRCLCD_LUNG | 1015762 | 1018770 | 1017267 | 1017267 | Missense_Mutation | G | A | p.T1845I |
| HSC39_STOMACH | 1015762 | 1018770 | 1017303 | 1017303 | Missense_Mutation | T | C | p.H1833R |
| CW2_LARGE_INTESTINE | 1015762 | 1018770 | 1017441 | 1017441 | Missense_Mutation | G | A | p.S1787L |
| ES6_BONE | 1015762 | 1018770 | 1017490 | 1017490 | Missense_Mutation | G | A | p.P1771S |
| HS746T_STOMACH | 1015762 | 1018770 | 1017561 | 1017561 | Missense_Mutation | G | T | p.T1747K |
| TGBC11TKB_STOMACH | 1015762 | 1018770 | 1017577 | 1017577 | Missense_Mutation | T | C | p.T1742A |
| UO31_KIDNEY | 1015762 | 1018770 | 1017771 | 1017771 | Missense_Mutation | C | A | p.G1677V |
| OCILY12_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1017801 | 1017801 | Missense_Mutation | G | T | p.T1667K |
| NCCSTCK140_STOMACH | 1015762 | 1018770 | 1017847 | 1017847 | Missense_Mutation | T | C | p.T1652A |
| KGN_OVARY | 1015762 | 1018770 | 1017847 | 1017847 | Missense_Mutation | T | C | p.T1652A |
| NCIH647_LUNG | 1015762 | 1018770 | 1017859 | 1017859 | Missense_Mutation | T | C | p.M1648V |
| KYSE140_OESOPHAGUS | 1015762 | 1018770 | 1017884 | 1017884 | Missense_Mutation | C | G | p.M1639I |
| HS834T_FIBROBLAST | 1015762 | 1018770 | 1018036 | 1018036 | Missense_Mutation | C | T | p.G1589S |
| C33A_CERVIX | 1015762 | 1018770 | 1018098 | 1018098 | Missense_Mutation | C | T | p.R1568K |
| HUNS1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1018198 | 1018198 | Missense_Mutation | G | A | p.P1535S |
| OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1018461 | 1018461 | Missense_Mutation | A | G | p.V1447A |
| KMRC1_KIDNEY | 1015762 | 1018770 | 1018461 | 1018461 | Missense_Mutation | A | G | p.V1447A |
| OVMIU_OVARY | 1015762 | 1018770 | 1018461 | 1018461 | Missense_Mutation | A | G | p.V1447A |
| NB5_AUTONOMIC_GANGLIA | 1015762 | 1018770 | 1018474 | 1018474 | Missense_Mutation | G | A | p.L1443F |
| SNU668_STOMACH | 1015762 | 1018770 | 1018492 | 1018492 | Missense_Mutation | A | G | p.S1437P |
| HCT15_LARGE_INTESTINE | 1015762 | 1018770 | 1018606 | 1018606 | Missense_Mutation | T | C | p.T1399A |
| SNU1040_LARGE_INTESTINE | 1015762 | 1018770 | 1018606 | 1018606 | Missense_Mutation | T | G | p.T1399P |
| DND41_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1015762 | 1018770 | 1018660 | 1018660 | Missense_Mutation | T | C | p.T1381A |
| EFO27_OVARY | 1015762 | 1018770 | 1018764 | 1018764 | Missense_Mutation | G | A | p.S1346L |
| MEWO_SKIN | 1019275 | 1019496 | 1019328 | 1019328 | Missense_Mutation | C | T | p.R1326Q |
| DU145_PROSTATE | 1019275 | 1019496 | 1019371 | 1019371 | Missense_Mutation | T | G | p.T1312P |
| FADU_UPPER_AERODIGESTIVE_TRACT | 1019275 | 1019496 | 1019371 | 1019371 | Missense_Mutation | T | G | p.T1312P |
| OCIM1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1019275 | 1019496 | 1019478 | 1019478 | Missense_Mutation | G | A | p.T1276M |
| RKO_LARGE_INTESTINE | 1030573 | 1030780 | 1030599 | 1030599 | Missense_Mutation | C | T | p.R289H |
| GP5D_LARGE_INTESTINE | 1030573 | 1030780 | 1030635 | 1030635 | Missense_Mutation | T | C | p.Y277C |
| IM95_STOMACH | 1030573 | 1030780 | 1030705 | 1030705 | Missense_Mutation | A | G | p.C254R |
| CAS1_CENTRAL_NERVOUS_SYSTEM | 1030573 | 1030780 | 1030776 | 1030776 | Missense_Mutation | C | T | p.R230Q |
| C125PM_LARGE_INTESTINE | 1031169 | 1031259 | 1031187 | 1031187 | Missense_Mutation | C | T | p.E186K |
| RKO_LARGE_INTESTINE | 1031169 | 1031259 | 1031190 | 1031190 | Missense_Mutation | T | C | p.N185D |
| C33A_CERVIX | 1015762 | 1018770 | 1015966 | 1015966 | Nonsense_Mutation | G | A | p.R2279* |
| SW756_CERVIX | 1015762 | 1018770 | 1016571 | 1016571 | Nonsense_Mutation | G | T | p.S2077* |
| NCIH747_LARGE_INTESTINE | 1015762 | 1018770 | 1016571 | 1016571 | Nonsense_Mutation | G | T | p.S2077* |
| TC138_BONE | 1015762 | 1018770 | 1018491 | 1018491 | Nonsense_Mutation | G | C | p.S1437* |
| PLCPRF5_LIVER | 1031169 | 1031259 | 1031224 | 1031224 | Nonsense_Mutation | G | T | p.C173* |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for MUC6 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MUC6 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MUC6 |
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RelatedDrugs for MUC6 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MUC6 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| MUC6 | C0038356 | Stomach Neoplasms | 1 | CTD_human |
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