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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in TCGA

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Exon skipping events with PSIs in GTEx

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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SNVs in the skipped exons with depth of coverage

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

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Related drugs with this gene

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Related diseases with this gene

Gene summary for MMP2

check button Gene summary
Gene informationGene symbol

MMP2

Gene ID

4313

Gene namematrix metallopeptidase 2
SynonymsCLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1
Cytomap

16q12.2

Type of geneprotein-coding
Description72 kDa type IV collagenasecollagenase type IV-Amatrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)matrix metalloproteinase-2matrix metalloproteinase-IIneutrophil gelatinase
Modification date20180519
UniProtAcc

P08253

ContextPubMed: MMP2 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
MMP2

GO:0006508

proteolysis

15863497


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Exon skipping events across known transcript of Ensembl for MMP2 from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Gene isoform structures and expression levels for MMP2

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


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Exon skipping events with PSIs in TCGA for MMP2

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_1365621655517927:55518076:55519210:55519339:55519515:5551968855519210:55519339ENSG00000087245.8ENST00000437642.2,ENST00000570308.1,ENST00000564864.1,ENST00000219070.4,ENST00000543485.1
exon_skip_1365641655522574:55522628:55523562:55523736:55525712:5552586855523562:55523736ENSG00000087245.8ENST00000437642.2,ENST00000570308.1,ENST00000219070.4,ENST00000543485.1
exon_skip_1365671655522573:55522628:55525712:55525868:55527069:5552720555525712:55525868ENSG00000087245.8ENST00000570283.1
exon_skip_1365681655523562:55523736:55525712:55525868:55527069:5552720555525712:55525868ENSG00000087245.8ENST00000437642.2,ENST00000570308.1,ENST00000219070.4,ENST00000543485.1
exon_skip_1365711655532200:55532360:55536690:55536800:55539250:5553943755536690:55536800ENSG00000087245.8ENST00000437642.2,ENST00000570308.1,ENST00000219070.4,ENST00000543485.1

check button PSI values of skipped exons in TCGA.
psi tcga

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Exon skipping events with PSIs in GTEx for MMP2

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_1365621655517927:55518076:55519210:55519339:55519515:5551968855519210:55519339ENSG00000087245.8ENST00000570308.1,ENST00000219070.4,ENST00000564864.1,ENST00000543485.1,ENST00000437642.2
exon_skip_1365641655522574:55522628:55523562:55523736:55525712:5552586855523562:55523736ENSG00000087245.8ENST00000570308.1,ENST00000219070.4,ENST00000543485.1,ENST00000437642.2
exon_skip_1365671655522573:55522628:55525712:55525868:55527069:5552720555525712:55525868ENSG00000087245.8ENST00000570283.1
exon_skip_1365681655523562:55523736:55525712:55525868:55527069:5552720555525712:55525868ENSG00000087245.8ENST00000570308.1,ENST00000219070.4,ENST00000543485.1,ENST00000437642.2
exon_skip_1365711655532200:55532360:55536690:55536800:55539250:5553943755536690:55536800ENSG00000087245.8ENST00000570308.1,ENST00000219070.4,ENST00000543485.1,ENST00000437642.2

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for MMP2

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000002190705553669055536800Frame-shift
ENST000002190705551921055519339In-frame
ENST000002190705552356255523736In-frame
ENST000002190705552571255525868In-frame

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST000002190705553669055536800Frame-shift
ENST000002190705551921055519339In-frame
ENST000002190705552356255523736In-frame
ENST000002190705552571255525868In-frame

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Infer the effects of exon skipping event on protein functional features for MMP2

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000002190703758660555192105551933910391167176219
ENST000002190703758660555235625552373615161689335393
ENST000002190703758660555257125552586816901845393445

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000002190703758660555192105551933910391167176219
ENST000002190703758660555235625552373615161689335393
ENST000002190703758660555257125552586816901845393445

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
P08253176219179181Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219186189Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219192195Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219197199Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219205208Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219209211Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1HOV
P08253176219213216Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219110660ChainID=PRO_0000028715;Note=72 kDa type IV collagenase
P08253176219178178Metal bindingNote=Zinc 1;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219180180Metal bindingNote=Zinc 1;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219185185Metal bindingNote=Calcium 3;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219186186Metal bindingNote=Calcium 3%3B via carbonyl oxygen;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219193193Metal bindingNote=Zinc 1;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219200200Metal bindingNote=Calcium 2%3B via carbonyl oxygen;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219202202Metal bindingNote=Calcium 2%3B via carbonyl oxygen;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219204204Metal bindingNote=Calcium 2;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219206206Metal bindingNote=Zinc 1;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219208208Metal bindingNote=Calcium 3;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219209209Metal bindingNote=Calcium 1;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219211211Metal bindingNote=Calcium 3;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219210210Natural variantID=VAR_032424;Note=D->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11431697;Dbxref=PMID:11431697
P08253176219110221RegionNote=Collagenase-like 1
P08253176219200203TurnOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253335393338341Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1GXD
P08253335393351355Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393358362Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393369371Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393374379Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393387389Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393110660ChainID=PRO_0000028715;Note=72 kDa type IV collagenase
P08253335393349375Disulfide bondOntology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00479
P08253335393363390Disulfide bondOntology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00479
P08253335393344392DomainNote=Fibronectin type-II 3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00479
P08253335393381384HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393222396RegionNote=Collagen-binding
P08253335393342346TurnOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253393445404404Active siteOntology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU10095
P08253393445394396Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253393445422424Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253393445110660ChainID=PRO_0000028715;Note=72 kDa type IV collagenase
P08253393445445660ChainID=PRO_0000391626;Note=PEX
P08253393445397408HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253393445435445HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253393445403403Metal bindingNote=Zinc 2%3B catalytic;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253393445407407Metal bindingNote=Zinc 2%3B catalytic;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253393445413413Metal bindingNote=Zinc 2%3B catalytic;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253393445400400Natural variantID=VAR_054996;Note=In MONA. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16542393;Dbxref=PMID:16542393
P08253393445404404Natural variantID=VAR_032425;Note=In MONA. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15691365;Dbxref=dbSNP:rs121912955,PMID:15691365
P08253393445222396RegionNote=Collagen-binding
P08253393445397465RegionNote=Collagenase-like 2
P08253393445414660RegionNote=Required for inhibitor TIMP2 binding


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
P08253176219179181Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219186189Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219192195Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219197199Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219205208Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219209211Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1HOV
P08253176219213216Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253176219110660ChainID=PRO_0000028715;Note=72 kDa type IV collagenase
P08253176219178178Metal bindingNote=Zinc 1;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219180180Metal bindingNote=Zinc 1;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219185185Metal bindingNote=Calcium 3;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219186186Metal bindingNote=Calcium 3%3B via carbonyl oxygen;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219193193Metal bindingNote=Zinc 1;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219200200Metal bindingNote=Calcium 2%3B via carbonyl oxygen;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219202202Metal bindingNote=Calcium 2%3B via carbonyl oxygen;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219204204Metal bindingNote=Calcium 2;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219206206Metal bindingNote=Zinc 1;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219208208Metal bindingNote=Calcium 3;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219209209Metal bindingNote=Calcium 1;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219211211Metal bindingNote=Calcium 3;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253176219210210Natural variantID=VAR_032424;Note=D->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11431697;Dbxref=PMID:11431697
P08253176219110221RegionNote=Collagenase-like 1
P08253176219200203TurnOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253335393338341Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1GXD
P08253335393351355Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393358362Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393369371Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393374379Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393387389Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393110660ChainID=PRO_0000028715;Note=72 kDa type IV collagenase
P08253335393349375Disulfide bondOntology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00479
P08253335393363390Disulfide bondOntology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00479
P08253335393344392DomainNote=Fibronectin type-II 3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00479
P08253335393381384HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253335393222396RegionNote=Collagen-binding
P08253335393342346TurnOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1EAK
P08253393445404404Active siteOntology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU10095
P08253393445394396Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253393445422424Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253393445110660ChainID=PRO_0000028715;Note=72 kDa type IV collagenase
P08253393445445660ChainID=PRO_0000391626;Note=PEX
P08253393445397408HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253393445435445HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3AYU
P08253393445403403Metal bindingNote=Zinc 2%3B catalytic;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253393445407407Metal bindingNote=Zinc 2%3B catalytic;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253393445413413Metal bindingNote=Zinc 2%3B catalytic;Ontology_term=ECO:0000250;evidence=ECO:0000250
P08253393445400400Natural variantID=VAR_054996;Note=In MONA. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16542393;Dbxref=PMID:16542393
P08253393445404404Natural variantID=VAR_032425;Note=In MONA. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15691365;Dbxref=dbSNP:rs121912955,PMID:15691365
P08253393445222396RegionNote=Collagen-binding
P08253393445397465RegionNote=Collagenase-like 2
P08253393445414660RegionNote=Required for inhibitor TIMP2 binding


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SNVs in the skipped exons for MMP2

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
LIHCTCGA-DD-A1EG-01exon_skip_136562
55519211555193395551926855519268Frame_Shift_DelC-p.A196fs
COADTCGA-AZ-4615-01exon_skip_136564
55523563555237365552359655523596Frame_Shift_DelC-p.A347fs
SKCMTCGA-Z2-A8RT-06exon_skip_136562
55519211555193395551932055519320Nonsense_MutationGAp.W213*
LUADTCGA-05-4382-01exon_skip_136568
exon_skip_136567
55525713555258685552585955525859Nonsense_MutationGTp.E443*

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
JHUEM7_ENDOMETRIUM55519211555193395551921955519219Missense_MutationGAp.D180N
GP5D_LARGE_INTESTINE55519211555193395551921955519219Missense_MutationGAp.D180N
NCIH322_LUNG55519211555193395551924655519246Missense_MutationGAp.G189R
NCIH513_PLEURA55519211555193395551925555519255Missense_MutationGTp.A192S
SCLC22H_LUNG55519211555193395551928955519289Missense_MutationGAp.G203E
SCLC21H_LUNG55519211555193395551928955519289Missense_MutationGAp.G203E
127399_SOFT_TISSUE55523563555237365552358055523581Missense_MutationGGAAp.G342K
KARPAS45_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE55523563555237365552365955523659Missense_MutationGAp.R368H
NCIH716_LARGE_INTESTINE55523563555237365552369455523694Missense_MutationACp.N380H
SKMEL30_SKIN55523563555237365552370955523709Missense_MutationCTp.R385C
FARAGE_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE55523563555237365552371055523710Missense_MutationGAp.R385H
P30OHK_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE55523563555237365552371055523710Missense_MutationGAp.R385H
SISO_CERVIX55523563555237365552371055523710Missense_MutationGAp.R385H
SW1271_LUNG55525713555258685552574355525743Missense_MutationAGp.E404G
NCIH460_LUNG55525713555258685552575455525754Missense_MutationGAp.A408T
NCIH1355_LUNG55525713555258685552577555525775Missense_MutationCAp.Q415K
SNU1040_LARGE_INTESTINE55525713555258685552582655525826Missense_MutationCTp.R432C
OMC1_CERVIX55536691555368005553679955536799Splice_SiteCTp.G626G

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for MMP2

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value
exon_skip_1365641655522574:55522628:55523562:55523736:55525712:5552586855523562:55523736ENST00000437642.2,ENST00000570308.1,ENST00000219070.4,ENST00000543485.1HNSCrs243849chr16:55523705C/T1.60e-03
exon_skip_1365641655522574:55522628:55523562:55523736:55525712:5552586855523562:55523736ENST00000437642.2,ENST00000570308.1,ENST00000219070.4,ENST00000543485.1KIRCrs243849chr16:55523705C/T2.00e-03
exon_skip_1365641655522574:55522628:55523562:55523736:55525712:5552586855523562:55523736ENST00000437642.2,ENST00000570308.1,ENST00000219070.4,ENST00000543485.1LUSCrs243849chr16:55523705C/T1.71e-03

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MMP2


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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MMP2


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RelatedDrugs for MMP2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
P08253DB01197Captopril72 kDa type IV collagenasesmall moleculeapproved

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RelatedDiseases for MMP2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
MMP2C0027627Neoplasm Metastasis5CTD_human
MMP2C0027626Neoplasm Invasiveness4CTD_human
MMP2C0006663Calcinosis2CTD_human
MMP2C0009404Colorectal Neoplasms2CTD_human
MMP2C0023890Liver Cirrhosis2CTD_human
MMP2C0023893Liver Cirrhosis, Experimental2CTD_human
MMP2C0027051Myocardial Infarction2CTD_human
MMP2C0376634Craniofacial Abnormalities2CTD_human
MMP2C1458155Mammary Neoplasms2CTD_human
MMP2C1850155TORG-WINCHESTER SYNDROME2CTD_human;ORPHANET;UNIPROT
MMP2C0001973Alcoholic Intoxication, Chronic1PSYGENET
MMP2C0003493Aortic Diseases1CTD_human
MMP2C0003496Aortic Rupture1CTD_human
MMP2C0003873Rheumatoid Arthritis1CTD_human
MMP2C0005940Bone Diseases1CTD_human
MMP2C0005944Metabolic Bone Disorder1CTD_human
MMP2C0005967Bone neoplasms1CTD_human
MMP2C0011853Diabetes Mellitus, Experimental1CTD_human
MMP2C0011882Diabetic Neuropathies1CTD_human
MMP2C0017636Glioblastoma1CTD_human
MMP2C0020538Hypertensive disease1CTD_human
MMP2C0021368Inflammation1CTD_human
MMP2C0023283Leishmaniasis, Cutaneous1CTD_human
MMP2C0023891Liver Cirrhosis, Alcoholic1CTD_human
MMP2C0024143Lupus Nephritis1CTD_human
MMP2C0024689Mandibular Diseases1CTD_human
MMP2C0024796Marfan Syndrome1CTD_human
MMP2C0024950Maxillary Diseases1CTD_human
MMP2C0027439Nasopharyngeal Neoplasms1CTD_human
MMP2C0028433Nose Neoplasms1CTD_human
MMP2C0029172Oral Submucous Fibrosis1CTD_human
MMP2C0029445Bone necrosis1CTD_human
MMP2C0029463Osteosarcoma1CTD_human
MMP2C0034067Pulmonary Emphysema1CTD_human
MMP2C0034069Pulmonary Fibrosis1CTD_human
MMP2C0043094Weight Gain1CTD_human
MMP2C0085762Alcohol abuse1PSYGENET
MMP2C0162872Aortic Aneurysm, Thoracic1CTD_human
MMP2C1336708Testicular Germ Cell Tumor1CTD_human
MMP2C2239176Liver carcinoma1CTD_human
MMP2C2931822Nasopharyngeal carcinoma1CTD_human
MMP2C2936380Neointima1CTD_human
MMP2C2937358Cerebral Hemorrhage1CTD_human
MMP2C4277682Chemical and Drug Induced Liver Injury1CTD_human